Blar i NTNU Open på forfatter "Zwart, John-Anker"
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Parental migraine in relation to migraine in offspring: Family linkage analyses from the HUNT Study
Børte, Sigrid; Zwart, John-Anker; Stensland, Synne; Hagen, Knut; Winsvold, Bendik K S (Journal article; Peer reviewed, 2019)Background Migraine is known to run in families. While some clinical studies have indicated that migraine is disproportionally transmitted through the maternal line, this has not been examined in a population-based ... -
Physical activity as a predictor for chronic musculoskeletal complaints: Results from the Nord-Trøndelag Heath Study
Holthe, H; Werpen, Hanne; Zwart, John-Anker; Hagen, Knut (Journal article; Peer reviewed, 2008-12-01)Background: Physical inactivity is associated with several diseases, but studies evaluating the association between chronic musculoskeletal complaints (MSCs) and physical exercise have shown conflicting results. The aim ... -
Physical activity level at work and risk of chronic low back pain: A follow-up in the Nord-Trøndelag Health Study
Heuch, Ingrid; Heuch, Ivar; Hagen, Knut; Zwart, John-Anker (Journal article; Peer reviewed, 2017)Background: Physical activity in leisure time seems to reduce the risk of low back pain, but it is not known whether occupational activity, as recorded in a representative working population, produces a higher or lower ... -
Prognostic Factors for Persistent Leg-Pain in Patients Hospitalized with Acute Sciatica
Fjeld, Olaf Randall; Grotle, Margreth; Siewers, Vibeke; Pedersen, Linda Margareth; Nilsen, Kristian Bernhard; Zwart, John-Anker (Journal article; Peer reviewed, 2017)Study Design. Prospective cohort study. Objective. To identify potential prognostic factors for persistent leg-pain at 12 months among patients hospitalized with acute severe sciatica. Summary of Background Data. The ... -
Psychophysical or spinal reflex measures when assessing conditioned pain modulation?
Lie, Marie; Petriu, Elena; Matre, Dagfinn; Hansson, Per; Andersen, Ole Kæseler; Zwart, John-Anker; Nilsen, Kristian Bernhard (Journal article; Peer reviewed, 2019)Background Assessing conditioning pain modulation (CPM) with spinal reflex measures may produce more objective and stable CPM effects than using psychophysical measures. The aim of the study was to compare the CPM effect ... -
Remission of chronic headache: An 11-year follow-up study. Data from the Nord-Trøndelag Health Surveys 1995–1997 and 2006–2008
Hagen, Knut; Kristoffersen, Espen Saxhaug; Winsvold, Bendik K S; Stovner, Lars Jacob; Zwart, John-Anker (Journal article; Peer reviewed, 2018)Objectives To estimate remission rates of chronic headache and predictors of remission. Methods In this longitudinal population-based cohort study, we used validated headache questionnaire data from the second (1995–1997, ... -
Shared genetic risk between migraine and coronary artery disease: A genome-wide analysis of common variants
Winsvold, Bendik K S; Bettella, Francesco; Witoelar, A; Anttila, Verneri; Gormley, Padhraig; Kurth, Tobias; Terwindt, Gisela M; Freilinger, Tobias; Frei, Oleksandr; Shadrin, Alexey A.; Wang, Yunpeng; Dale, Anders; Van Den Maagdenberg, Arn M.J.M.; Chasman, Daniel I; Nyholt, Dale R; Palotie, Aarno; Andreassen, Ole Andreas; Zwart, John-Anker (Journal article; Peer reviewed, 2017)Migraine is a recurrent pain condition traditionally viewed as a neurovascular disorder, but little is known of its vascular basis. In epidemiological studies migraine is associated with an increased risk of cardiovascular ... -
The association between diabetes mellitus, glucose, and chronic musculoskeletal complaints. Results from the Nord-Trondelag Health Study
Hoff, Ole Martin; Midthjell, Kristian; Zwart, John-Anker; Hagen, Knut (Journal article; Peer reviewed, 2008)Background: The relationship between diabetes mellitus (DM) and chronic musculoskeletal complaints (MSCs) is unclear. The aim of this study was to investigate the association between DM, non-fasting glucose and chronic ... -
The causal role of smoking on the risk of headache. A Mendelian randomization analysis in the HUNT Study
Johnsen, Marianne Bakke; Winsvold, Bendik K S; Børte, Sigrid; Vie, Gunnhild Åberge; Pedersen, Linda Margareth; Storheim, Kjersti; Skorpen, Frank; Hagen, Knut; Bjørngaard, Johan Håkon; Åsvold, Bjørn Olav; Zwart, John-Anker (Journal article; Peer reviewed, 2018)Background and purpose Headache has been associated with various lifestyle and psychosocial factors, one of which is smoking. The aim of the present study was to investigate whether the association between smoking intensity ... -
The causal role of smoking on the risk of hip or knee replacement due to primary osteoarthritis: a Mendelian randomisation analysis of the HUNT study
Johnsen, Marianne Bakke; Vie, Gunnhild Åberge; Winsvold, Bendik K S; Bjørngaard, Johan Håkon; Åsvold, Bjørn Olav; Gabrielsen, Maiken Elvestad; Pedersen, Linda Margareth; Hellevik, Alf Inge; Langhammer, Arnulf; Furnes, Ove; Flugsrud, Gunnar B; Skorpen, Frank; Romundstad, Pål Richard; Storheim, Kjersti; Nordsletten, Lars; Zwart, John-Anker (Journal article; Peer reviewed, 2017)Objective Smoking has been associated with a reduced risk of hip and knee osteoarthritis (OA) and subsequent joint replacement. The aim of the present study was to assess whether the observed association is likely to be ... -
The impact of headache and chronic musculoskeletal complaints on the risk of insomnia: longitudinal data from the Nord-Trondelag health study
Ødegård, Siv Steinsmo; Sand, Trond; Engstrøm, Morten; Zwart, John-Anker; Hagen, Knut (Journal article; Peer reviewed, 2013)Background A strong relationship between insomnia and painful disorders has been found, but it is still unclear whether chronic pain leads to insomnia. There is a need of large-scale prospective studies to evaluate if ... -
The mediating effect of body mass index on the relationship between smoking and hip or knee replacement due to primary osteoarthritis. A population-based cohort study (the HUNT study).
Johnsen, Marianne Bakke; Hellevik, Alf Inge; Småstuen, Milada C; Langhammer, Arnulf; Furnes, Ove; Flugsrud, Gunnar B; Nordsletten, Lars; Zwart, John-Anker; Storheim, Kjersti (Journal article; Peer reviewed, 2017)To investigate the total effect of smoking on total hip or knee replacement (THR/TKR) due to primary osteoarthritis (OA) and to quantify the indirect effect of smoking through body mass index (BMI). Participants from the ... -
The relationship between headache and religious attendance (the Nord-Trøndelag health study-HUNT)
Tronvik, Erling; Sørensen, Torgeir; Linde, Mattias; Bendtsen, Lars; Artto, Ville; Laurell, Katarina; Kallela, Mikko; Zwart, John-Anker; Hagen, Knut (Journal article; Peer reviewed, 2014)Background Religious belief can be used as a pain coping strategy. Our purpose was to evaluate the relationship between headache and religious activity using prospective data from a large population-based study. Meth ... -
The relationship of anxiety, depression and behavioral problems with recurrent headache in late adolescence - a Young-HUNT follow-up study
Blaauw, Brit Andenes; Dyb, Grete; Hagen, Knut; Holmen, Turid Lingaas; Linde, Mattias; Wentzel-Larsen, Tore; Zwart, John-Anker (Journal article; Peer reviewed, 2015)Background The comorbidity of headache and psychiatric symptoms is a well-recognized clinical phenomenon, but there are only limited data regarding the temporal relationship between headache and symptoms of anxiety and ... -
Time trends of major headache diagnoses and predictive factors. Data from three Nord-Trøndelag health surveys
Hagen, Knut; Stovner, Lars Jacob; Zwart, John-Anker (Journal article; Peer reviewed, 2020)Aims The primary aim of this study was to investigate time trends of major headache diagnoses using cross-sectional data from two population-based health surveys. In addition, we aimed to perform a longitudinal assessment ... -
Urinary albumin excretion as a marker of endothelial dysfunction in migraine sufferers: the HUNT study, Norway
Jacobsen, Line Melå; Winsvold, Bendik Kristoffer Slagsvold; Romundstad, Solfrid; Pripp, Are Hugo; Holmen, Jostein; Zwart, John-Anker (Journal article; Peer reviewed, 2013)Objective: To investigate urine albumin leakage as a marker of endothelial dysfunction in migraine patients. Design: A population-based health study. Participants: 303 patients with migraine, 1009 patients with ... -
Variation in serum PCSK9 (proprotein convertase subtilisin/kexin type 9), cardiovascular disease risk, and an investigation of potential unanticipated effects of PCSK9 inhibition
Brumpton, Ben Michael; Fritsche, Lars; Zheng, Jie; Nielsen, Jonas Bille; Mannila, Maria Nastase; Surakka, Ida; Rasheed, Humaira; Vie, Gunnhild Åberge; Graham, Sarah E.; Gabrielsen, Maiken Elvestad; Laugsand, Lars Erik; Aukrust, Pål; Vatten, Lars Johan; Damås, Jan Kristian; Ueland, Thor; Janszky, Imre; Zwart, John-Anker; van't Hooft, Ferdinand M.; Seidah, Nabil Georges; Hveem, Kristian; Willer, Cristen; Smith, George Davey; Åsvold, Bjørn Olav (Peer reviewed; Journal article, 2019)PCSK9 (proprotein convertase subtilisin/kexin type 9) inhibitors reduce serum LDL (low-density lipoprotein) cholesterol (LDL-C) by increasing uptake in the liver. Although some long-term trials have evaluated their safety, ...