Blar i NTNU Open på forfatter "Kaasa, Stein"

Viser treff 41-60 av 101

    • Health care providers underestimate symptom intensities of cancer patients: A multicenter European study 

      Laugsand, Eivor Alette; Sprangers, Mirjam A. G.; Bjordal, Kristin; Skorpen, Frank; Kaasa, Stein; Klepstad, Pål (Journal article; Peer reviewed, 2010)
      Background: Many patients with advanced cancer depend upon health care providers for symptom assessment. The extent of agreement between patient and provider symptom assessments and the association of agreement with ...

    • Health-related quality of life in patients with advanced melanoma treated with ipilimumab: prognostic implications and changes during treatment 

      Aamdal, Elin; Skovlund, Eva; Jacobsen, Kari Dolven; Straume, Oddbjørn; Kersten, Christian; Herlofsen, Oluf; Karlsen, Jarle; Hussain, Israr; Amundsen, Anita; Dalhaug, Astrid; Nyakas, Marta Sølvi; Hagene, Kirsten Thorin; Holmsen, Kjersti; Aamdal, Steinar; Kaasa, Stein; Guren, Tormod Kyrre; Kyte, Jon A (Peer reviewed; Journal article, 2022)
      Background We have previously reported that the safety and efficacy of ipilimumab in real-world patients with metastatic melanoma were comparable to clinical trials. Few studies have explored health-related quality of ...

    • Identification of genetic polymorphisms modulating nausea and vomiting in two series of opioid-treated cancer patients 

      Colombo, Francesca; Pintarelli, Giulia; Galvan, Antonella; Noci, Sara; Corli, Oscar; Skorpen, Frank; Klepstad, Pål; Kaasa, Stein; Pigni, Alessandra; Brunelli, Cinzia; Roberto, Anna; Piazza, Rocco; Pirola, Alessandra; Gambacorti-Passerini, Carlo; Caraceni, Augusto Tomasso Giovanni (Peer reviewed; Journal article, 2020)
      Nausea and vomiting are often associated with opioid analgesia in cancer patients; however, only a subset of patients develop such side effects. Here, we tested the hypothesis that the occurrence of nausea and vomiting is ...

    • Image-Guided Radiotherapy for Prostate Cancer and Side Effects after Treatment 

      Tøndel, Hanne (Doctoral theses at NTNU;2019:62, Doctoral thesis, 2019)
      Norsk sammendrag Prostatakreft er den vanligste kreftsykdommen blant norske menn med nesten 5000 nye tilfeller diagnostisert i 2016. Prognosen ved lokalisert sykdom er god og samlet 5-års overlevelse er nå godt over 90%. ...

    • Implementing a Standardized Care Pathway Integrating Oncology, Palliative Care and Community Care in a Rural Region of Mid-Norway 

      Brenne, Anne-Tove; Løhre, Erik T; Knudsen, Anne Kari; Thronæs, Morten; Lund, Jo-Åsmund; Kongshaug, Nina; Neverdal, Marte Nilssen; Rystad, Kristina Edvardsen; Johansen, Marianne Haug; Braseth, Tone Inga; Kaasa, Stein (Peer reviewed; Journal article, 2021)
      Introduction To improve quality across levels of care, we developed a standardized care pathway (SCP) integrating palliative and oncology services for hospitalized and home-dwelling palliative cancer patients in a rural ...

    • Inflammatory Markers and Radiotherapy Response in Patients With Painful Bone Metastases 

      Habberstad, Ragnhild H; Aass, Nina Kathrine; Mollnes, Tom Eirik; Damås, Jan Kristian; Brunelli, Cinzia; Rossi, Romina; Garcia-Alonso, Elena; Kaasa, Stein; Klepstad, Pål (Peer reviewed; Journal article, 2022)
      Context Inflammation is proposed to influence tumor response in radiotherapy (RT). Clinical studies to investigate the relationship between inflammatory markers and RT response is warranted to understand the variable RT ...

    • Informing cancer patients 

      Berger, Ola (Doctoral theses at NTNU;2017:129, Doctoral thesis, 2017)
      Norsk sammendrag: Målsetningen med ph.d.-prosjektet var å undersøke pasientinformasjon i kreftbehandling og kreftforskning. Vi tror at resultatene kan brukes i videre arbeid med å forbedre rutiner for pasientinformasjon ...

    • Innate immune signalling genetics of pain, cognitive dysfunction and sickness symptoms in cancer pain patients treated with transdermal fentanyl 

      Barratt, Daniel T.; Klepstad, Pål; Dale, Ola; Kaasa, Stein; Somogyi, Andrew A. (Peer reviewed; Journal article, 2015)
      Common adverse symptoms of cancer and chemotherapy are a major health burden; chief among these is pain, with opioids including transdermal fentanyl the mainstay of treatment. Innate immune activation has been implicated ...

    • Integraton between oncology and palliatve care: A plan for the next decade? 

      Kaasa, Stein; Knudsen, Anne Kari; Lundeby, Tonje; Loge, Jon Håvard (Journal article; Peer reviewed, 2017)
      With the groundbreaking works of the three Milan professors, i.e. Bonadonna, Veronesi, and Ventafridda, in the 1980’s as the starting point, this article aims to shed light on the potential benefits of a closer and more ...

    • Ipilimumab in a real-world population: A prospective Phase IV trial with long-term follow-up 

      Aamdal, Elin; Jacobsen, Kari Dolven; Straume, Oddbjørn; Kersten, Christian; Herlofsen, Oluf; Karlsen, Jarle; Hussain, Israr; Amundsen, Anita; Dalhaug, Astrid; Nyakas, Marta Sølvi; Schuster, Cornelia; Hagene, Kirsten Thorin; Holmsen, Kjersti; Russnes, Hege Elisabeth Giercksky; Skovlund, Eva; Kaasa, Stein; Aamdal, Steinar; Kyte, Jon A.; Guren, Tormod Kyrre (Peer reviewed; Journal article, 2021)
      Ipilimumab was the first treatment that improved survival in advanced melanoma. Efficacy and toxicity in a real-world setting may differ from clinical trials, due to more liberal eligibility criteria and less intensive ...

    • Is it possible to detect an improvement in cancer pain management? A comparison of two Norwegian cross-sectional studies conducted 5 years apart. 

      Thronæs, Morten; Raj, Sunil; Brunelli, Cinzia; Almberg, Sigrun Saur; Vagnildhaug, Ola Magne; Bruheim, Susanna; Helgheim, Birgit; Kaasa, Stein; Knudsen, Anne Kari (Journal article; Peer reviewed, 2016)
      Purpose: Cancer pain (CP) management is challenging. In recent years, efforts were undertaken to achieve better CP management, e.g. clinical research, new treatment modalities, development of guidelines, education, and ...

    • Is there a genetic cause of appetite loss? - An explorative study in 1853 cancer patients 

      Solheim, Tora Skeidsvoll; Fayers, Peter; Fladvad, Torill; Tan, Ben; Skorpen, Frank; Fearon, Kenneth C.; Baracos, Vickie; Klepstad, Pål; Strasser, Florian; Kaasa, Stein (Journal article; Peer reviewed, 2012)
      Background Appetite loss has a major impact on cancer patients. It is exceedingly prevalent, is a prognostic indicator and is associated with inferior quality of life. Cachexia is a multi‐factorial syndrome defined by a ...

    • Longitudinal Associations between Exercise and Pain in the General Population - The HUNT Pain Study 

      Landmark, Tormod; Romundstad, Pål Richard; Borchgrevink, Petter Chr.; Kaasa, Stein; Dale, Ola (Journal article; Peer reviewed, 2013)
      Background: Population-based studies have reported conflicting findings on the relationship between physical activity and pain, and most studies reporting a relationship are cross sectional. Temporal relationships are ...

    • Measurement of health-related quality of life during chemotherapy -the importance of timing 

      Kristensen, Are Korsnes; Solheim, Tora Skeidsvoll; Amundsen, Tore; Hjelde, Harald Harris; Kaasa, Stein; Sørhaug, Sveinung; Grønberg, Bjørn Henning (Journal article; Peer reviewed, 2017)
      Background: Side effects of chemotherapy may occur at different time-points in the treatment cycle, and the exact assessment time relative to chemotherapy may affect HRQoL scores. The current study examined the variation ...

    • Mild to Moderate Cognitive Impairment Does Not Affect the Ability to Self-Report Important Symptoms in Patients With Cancer: A Prospective Longitudinal Multinational Study (EPCCS) 

      Ekström, Magnus P.; Palmqvist, Sebastian; Currow, David C.; Sjøgren, Per; Kurita, Geana Paula; Jakobsen, Gunnhild; Kaasa, Stein; Hjermstad, Marianne Jensen (Peer reviewed; Journal article, 2020)
      Context Patients with advanced cancer commonly suffer from both distressing symptoms and cognitive impairment, but the effect of cognitive impairment on the reliability and validity of symptom self-report is unknown. ...

    • New genetic signatures associated with cancer cachexia as defined by low skeletal muscle index and weight loss. 

      Johns, Neil; Stretch, C; Tan, BH; Solheim, Tora Skeidsvoll; Sørhaug, Sveinung; Stephens, NA; Gioulbasanis, Ioannis; Skipworth, RJ; Deans, DA; Vigano, Antonio A.L.; Ross, JA; Bathe, OF; Tremblay, ML; Kaasa, Stein; Strasser, Florian; Gagnon, B; Baracos, VE; Damaraju, S; Fearon, KC (Peer reviewed; Journal article, 2017)
      Background Cachexia affects the majority with advanced cancer. Based on current demographic and clinical factors, it is not possible to predict who will develop cachexia or not. Such variation may, in part, be due to ...

    • Norwegian reference values for the Short-Form Health Survey 36: development over time 

      Jacobsen, Ellisiv Lærum; Bye, Asta; Aass, Nina Kathrine; Fosså, Sophie Dorothea; Grotmol, Kjersti Støen; Kaasa, Stein; Loge, Jon Håvard; Moum, Torbjørn Åge; Hjermstad, Marianne Jensen (Journal article; Peer reviewed, 2017)
      Purpose Reference values for patient-reported outcome measures are useful for interpretation of results from clinical trials. The study aims were to collect Norwegian SF-36 reference values and compare with data from 1996 ...

    • Overall survival after initial radiotherapy for brain metastases; a population based study of 2140 patients with non-small cell lung cancer 

      Karlsson, Astrid Telhaug; Hjermstad, Marianne Jensen; Omdahl, Therese; Aass, Nina Kathrine; Skovlund, Eva; Hellebust, Taran Paulsen; Johansen, Safora; Kaasa, Stein; Yri, Olav Erich (Peer reviewed; Journal article, 2021)
      Background Brain metastases (BM) occur in about 30% of all patients with non-small cell lung cancer (NSCLC). BM treatment guidelines recommend more frequent use of stereotactic radiotherapy (SRT). Overall, studies report ...

    • P-selectin genotype is associated with the development of cancer cachexia 

      Tan, Benjamin HL; Fladvad, Torill; Braun, TP; Vigano, Antonio A.L.; Strasser, Florian; Deans, DAC; Skipworth, R.J.; Skeidsvoll, Tora Lång; Damaraju, S; Ross, JA; Kaasa, Stein; Marks, DL; Baracos, Vickie; Skorpen, Frank; Fearon, Kenneth C. (Journal article; Peer reviewed, 2012)
      The variable predisposition to cachexia may, in part, be due to the interaction of host genotype. We analyzed 129 single nucleotide polymorphisms (SNPs) in 80 genes for association with cachexia based on degree of weight ...

    • Pain Intensity Factors Changing Breakthrough Pain Prevalence in Patients with Advanced Cancer: A Secondary Analysis of a Cross-Sectional Observational International Study 

      Løhre, Erik Torbjørn; Hjermstad, Marianne Jensen; Brunelli, Cinzia; Knudsen, Anne Kari; Kaasa, Stein; Klepstad, Pål (Journal article; Peer reviewed, 2018)
      Introduction Different definitions of breakthrough pain (BTP) influence the observed BTP prevalence. This study examined BTP prevalence variability due to use of different cutoffs for controlled background pain, different ...