Browsing NTNU Open by Title

Now showing items 38243-38262 of 100424

    • Gene Mutation Prediction System for Prostate Cancer 

      Thoresen Kristian Bjørn (Master thesis, 2021)
      This report explores how a gene mutation prediction system can be applied in the field of prostate cancer with a focus on creating such a system through experiments. Genes determines how a cell develops so knowing the ...

    • Gene Network Inference and Biochemical Assessment Delineates GPCR Pathways and CREB Targets in Small Intestinal Neuroendocrine Neoplasia 

      Drozdov, Ignat; Svejda, Bernhard; Gustafsson, Björn; Mane, S; Pfragner, Roswitha; Kidd, Mark; Modlin, Irvin M (Journal article; Peer reviewed, 2011)
      Small intestinal (SI) neuroendocrine tumors (NET) are increasing in incidence, however little is known about their biology. High throughput techniques such as inference of gene regulatory networks from microarray experiments ...

    • Gene Ontology annotation of sequence-specific DNA binding transcription factors: setting the stage for a large-scale curation effort 

      Tripathi, Sushil; Christie, K R; Balakrishnan, Ravin; Huntley, R; Hill, D P; Thommesen, Liv; Blake, J A; Kuiper, Martin; Lægreid, Astrid (Journal article; Peer reviewed, 2013)
      Transcription factors control which information in a genome becomes transcribed to produce RNAs that function in the biological systems of cells and organisms. Reliable and comprehensive information about transcription ...

    • Gene Ontology annotation of sequence-specific DNA binding transcription factors: setting the stage for a large-scale curation effort 

      Tripathi, Sushil; Christie, KR; Balakrishnan, Ravin; Huntley, R; Hill, DP; Thommesen, Liv; Blake, JA; Kuiper, Martin; Lægreid, Astrid (Journal article; Peer reviewed, 2013)
      Transcription factors control which information in a genome becomes transcribed to produce RNAs that function in the biological systems of cells and organisms. Reliable and comprehensive information about transcription ...

    • The Gene Ontology resource: enriching a GOld mine 

      Carbon, Seth J.; Douglass, Eric; Good, Benjamin M; Unni, Deepak R; Harris, Nomi L.; Mungall, Christopher J.; Basu, Siddartha; Chisholm, Rex L.; Dodson, Robert J.; Hartline, Eric; Fey, Petra; Thomas, Paul D.; Albou, Laurent-Philippe; Ebert, Dustin; Kesling, Michael J; Mi, Huaiyu; Muruganujan, Anushya; Huang, Xiaosong; Mushayahama, Tremayne; LaBonte, Sandra A.; Siegele, Deborah A.; Antonazzo, Giulia; Attrill, Helen; Brown, Nick H.; Garapati, Phani; Marygold, Steven J.; Trovisco, Vitor; dos Santos, Gil; Falls, Kathleen; Tabone, Christopher; Zhou, Pinglei; Goodman, Joshua L.; Strelets, Victor B.; Thurmond, Jim; Garmiri, Penelope; Ishtiaq, Rizwan; Rodríguez-López, Milagros; Acencio, Marcio Luis; Kuiper, Martin; Lægreid, Astrid; Logie, Colin; Lovering, Ruth C.; Kramarz, Barbara; Saverimuttu, Shirin C.C.; Pinheiro, Sandra M.; Gunn, Heather; Su, Renzhi; Thurlow, Katherine E.; Chibucos, Marcus; Giglio, Michelle; Nadendla, Suvarna; Munro, James; Jackson, Rebecca; Duesbury, Margaret J.; del-Toro, Noemi; Meldal, Birgit H.M.; Paneerselvam, Kalpana; Perfetto, Livia; Porras, Pablo; Orchard, Sandra; Shrivastava, Anjali (Peer reviewed; Journal article, 2021)
      The Gene Ontology Consortium (GOC) provides the most comprehensive resource currently available for computable knowledge regarding the functions of genes and gene products. Here, we report the advances of the consortium ...

    • Gene regulation in three dimensions 

      Wittek, Kristian Thoresen (Master thesis, 2016)
      Gene regulation has traditionally mainly been viewed as a 1D and possibly 2D process. In the 1D view the genome is seen as a linear string of nucleotides, where one or more transcription factors (TFs) bind to transcription ...

    • Gene regulation knowledge commons: community action takes care of DNA binding transcription factors 

      Tripathi, Sushil; Vercruysse, Steven; Chawla, Konika; Christie, Karen R.; Blake, Judith A; Huntley, Rachael P.; Orchard, Sandra; Hermjakob, Henning; Thommesen, Liv; Lægreid, Astrid; Kuiper, Martin (Journal article; Peer reviewed, 2016)
      A large gap remains between the amount of knowledge in scientific literature and the fraction that gets curated into standardized databases, despite many curation initiatives. Yet the availability of comprehensive knowledge ...

    • Gene regulation knowledge commons: community action takes care of DNA binding transcription factors 

      Tripathi, Sushil; Vercruysse, Steven; Chawla, Konika; Christie, Karen R.; Blake, Judith A; Huntley, Rachael P.; Orchard, Sandra; Hermjakob, Henning; Thommesen, Liv; Lægreid, Astrid; Kuiper, Martin (Journal article; Peer reviewed, 2016)
      A large gap remains between the amount of knowledge in scientific literature and the fraction that gets curated into standardized databases, despite many curation initiatives. Yet the availability of comprehensive knowledge ...

    • The gene regulation knowledge commons: the action area of GREEKC 

      Kuiper, Martin; Bonello, Joseph; Fernández-Breis, Jesualdo Tomás; Bucher, Philipp; Futschik, Matthias E; Gaudet, Pascale; Kulakovskiy, Ivan V.; Licata, Luana; Logie, Colin; Lovering, Ruth C.; Makeev, Vsevolod J; Orchard, Sandra; Panni, Simona; Perfetto, Livia; Sant, David; Schulz, Stefan M.; Vercruysse, Steven; Zerbino, Daniel; Lægreid, Astrid (Peer reviewed; Journal article, 2022)
      As computational modeling becomes more essential to analyze and understand biological regulatory mechanisms, governance of the many databases and knowledge bases that support this domain is crucial to guarantee reliability ...

    • Gene regulation of carbon fixation, storage, and utilization in the diatom phaeodactylum tricornutum acclimated to light/dark cycles 

      Chauton, Matilde Skogen; Winge, Per; Brembu, Tore; Vadstein, Olav; Bones, Atle M. (Journal article; Peer reviewed, 2013)
      The regulation of carbon metabolism in the diatom Phaeodactylum tricornutum at the cell, metabolite, and gene expression levels in exponential fed-batch cultures is reported. Transcriptional profiles and cell chemistry ...

    • Gene signatures ESC, MYC and ERG-fusion are early markers of a potentially dangerous subtype of prostate cancer 

      Rye, Morten Beck; Bertilsson, Helena; Drabløs, Finn; Angelsen, Anders; Bathen, Tone Frost; Tessem, May-Britt (Journal article; Peer reviewed, 2014)
      Background Good prognostic tools for predicting disease progression in early stage prostate cancer (PCa) are still missing. Detection of molecular subtypes, for instance by using microarray gene technology, can give new ...

    • Gene Therapy: Chitosan Based Nanoparticles for siRNA Delivery in Human Cells 

      Klemetsaune, Liv Kvistad (Master thesis, 2009)

    • Genealogical, Clinical and Biochemical Studies in LRRK2 - associated Parkinson’s Disease 

      Johansen, Krisztina Kunszt (Doktoravhandlinger ved NTNU, 1503-8181; 2010:223, Doctoral thesis, 2010)
      Bakgrunn og målsetting Parkinson’s sykdom (PS) er den nest hyppigste nevrodegenerative sykdom og rammer 1-2% av befolkningen over 65 års alder og kjennetegnes hovedsakelig av tremor, bradykinesi og rigiditet. Diagnosen ...

    • Genekspresjonsanalyse av hsp70, cyp1a, p38 og nrf2 hos atlantisk laks ved eksponering for kobber in vivo og in vitro 

      Klokk, Otilie Elena; Saman, Intira (Bachelor thesis, 2023)
      Genekspresjon av ulike målgener i kommersiell atlantisk laks kan gi en indikasjon på fiskens helse og velferd. I denne studien blir det sett på stressrespons fra atlantisk laks in vivo, og in vitro. Økt kunnskap om hvordan ...

    • Genekspresjonsanalyse av muc5, muc18 og il4/13a fra gjellevev i atlantisk laks ved bruk av RT-qPCR – før, under og tre uker etter brønnbåttransport 

      Jakaviciute, Rugile; Møen, Johanna; Schioldborg, Amanda; Tvedt, Charlotte Hop (Bachelor thesis, 2022)
      Genekspresjon av muciner og interleukiner i kommersiell atlantisk laks kan gi en indikasjon på fiskens helse og velferd. I denne studien blir det sett på fiskens fysiologiske respons på transport fra settefiskanlegg på ...

    • General and abdominal obesity and incident asthma in adults: the HUNT study 

      Brumpton, Ben Michael; Langhammer, Arnulf; Romundstad, Pål Richard; Chen, Yue; Mai, Xiao-Mei (Journal article; Peer reviewed, 2013)
      Measures of body mass index (BMI) and waist circumference define general obesity and abdominal obesity respectively. While high BMI has been established as a risk factor for asthma in adults, waist circumference has seldom ...

    • General and alcohol-related social media use and mental health: A large-sample longitudinal study 

      Erevik, Eilin K.; Pallesen, Ståle; Vedaa, Øystein; Andreassen, Cecilie Schou; Dhir, Amandeep; Torsheim, Torbjørn (Peer reviewed; Journal article, 2020)
      The current study aimed to investigate if general and alcohol-related social media use predicts symptoms of depression and anxiety. Students in Bergen, Norway, participated in a Web-based survey during fall 2015 (T1) and ...

    • A General and Effective Method for Wall and Protrusion Separation from Facade Point Clouds 

      Cai, Shangshu; Zhang, Shuhang; Zhang, Wuming; Fan, Hongchao; Shao, Jie; Yan, Guangjian; Yu, Sisi; Li, Aiguang; Zhou, Guoqing (Peer reviewed; Journal article, 2023)
      As a critical prerequisite for semantic facade reconstruction, accurately separating wall and protrusion points from facade point clouds is required. The performance of traditional separation methods is severely limited ...

    • General body injury after sexual assault 

      Enerhaug, Hanna; Vigdel, Lena (Master thesis, 2022)
      Bakgrunn: Kvinner som har opplevd seksuelle overgrep kan søke hjelp hos et overgrepsmottak. Overgrepsmottaket tilbyr medisinsk hjelp, rettsmedisinsk undersøkelse og psykososial støtte. Som en del av den rettsmedisinske ...

    • General body injury after sexual assault 

      Enerhaug, Hanna; Vigdel, Lena (Master thesis, 2022)
      Bakgrunn: Kvinner som har opplevd seksuelle overgrep kan søke hjelp hos et overgrepsmottak. Overgrepsmottaket tilbyr medisinsk hjelp, rettsmedisinsk undersøkelse og psykososial støtte. Som en del av den rettsmedisinske ...