• Factors associated with internalizing or somatic symptoms in a cross-sectional study of school children in grades 1-10 

      Løhre, Audhild; Lydersen, Stian; Vatten, Lars Johan (Journal article; Peer reviewed, 2010)
      Background: School related factors that may contribute to children’s subjective health have not been extensively studied. We assessed whether factors assumed to promote health and factors assumed to have adverse effects were ...
    • FGD5 amplification in breast cancer patients is associated with tumor proliferation and a poorer prognosis 

      Valla, Marit; Engstrøm, Monica J; Ytterhus, Borgny; Hansen, Åse Kristin Skain; Akslen, Lars A.; Vatten, Lars Johan; Opdahl, Signe; Bofin, Anna M. (Journal article; Peer reviewed, 2017)
      Purpose Proliferation is a hallmark of cancer. Using a combined genomic approach, FGD5 amplification has been identified as a driver of proliferation in Luminal breast cancer. We aimed to describe FGD5 copy number change ...
    • Genome-wide association study identifies multiple risk loci for renal cell carcinoma 

      Scelo, Ghislaine; Purdue, Mark P.; Brown, Kevin M.; Johansson, Mattias; Wang, Zhaoming; Eckel-Passow, Jeanette E.; Ye, Yuanqing; Hofmann, Jonathan N.; Choi, Jiyeon; Foll, Matthieu; Gaborieau, Valerie; Machiela, Mitchell J.; Colli, Leandro M.; Li, Peng; Sampson, Joshua N.; Abedi-Ardekani, Behnoush; Besse, Celine; Blanche, Helene; Boland, Anne; Burdette, Laurie; Chabrier, Amelie; Durand, Geoffroy; Le Calvez-Kelm, Florence; Prokhortchouk, Egor; Robinot, Nivonirina; Skryabin, Konstantin G.; Wozniak, Magdalena B.; Yeager, Meredith; Basta-Jovanovic, Gordana; Dzamic, Zoran; Foretova, Lenka; Holcatova, Ivana; Janout, Vladimir; Mates, Dana; Mukeriya, Anush; Rascu, Stefan; Zaridze, David; Bencko, Vladimir; Cybulski, Cezary; Fabianova, Eleonora; Jinga, Viorel; Lissowska, Jolanta; Lubinski, Jan; Navratilova, Marie; Rudnai, Peter; Szeszenia-Dabrowska, Neonila; Benhamou, Simone; Cancel-Tassin, Geraldine; Cussenot, Olivier; Baglietto, Laura; Boeing, Heiner; Khaw, Kay-Tee; Weiderpass, Elisabete; Ljungberg, Börje; Sitaram, Raviprakash T.; Bruinsma, Fiona; Jordan, Susan J.; Severi, Gianluca; Winship, Ingrid; Hveem, Kristian; Vatten, Lars Johan; Fletcher, Tony; Koppova, Kvetoslava; Larsson, Susanna C.; Wolk, Alicja; Banks, Rosamonde E.; Selby, Peter J.; Easton, Douglas F.; Pharoah, Paul; Andreotti, Gabriella; Freeman, Laura E Beane; Koutros, Stella; Albanes, Demetrius; Männistö, Satu; Weinstein, Stephanie; Clark, Peter E.; Edwards, Todd L.; Lipworth, Loren; Gapstur, Susan M.; Stevens, Victoria L.; Carol, Hallie; Freedman, Matthew L.; Pomerantz, Mark M.; Cho, Eunyoung; Kraft, Peter; Preston, Mark A.; Wilson, Kathryn M.; Gaziano, J. Michael; Sesso, Howard D.; Black, Amanda; Freedman, Neal D.; Huang, Wen-Yi; Anema, John G.; Kahnoski, Richard J.; Lane, Brian R.; Noyes, Sabrina L.; Petillo, David; Teh, Bin Tean; Peters, Ulrike; White, Emily; Anderson, Garnet L.; Johnson, Lisa; Luo, Juhua; Buring, Julie; Lee, I-Min; Chow, Wong-Ho; Moore, Lee E.; Wood, Christopher; Eisen, Timothy; Henrion, Marc; Larkin, James; Barman, Poulami; Leibovich, Bradley C.; Choueiri, Toni K.; Lathrop, G. Mark; Rothman, Nathaniel; Deleuze, Jean-Francois; McKay, James D.; Parker, Alexander S.; Wu, Xifeng; Houlston, Richard S.; Brennan, Paul; Chanock, Stephen J. (Journal article; Peer reviewed, 2017)
      Previous genome-wide association studies (GWAS) have identified six risk loci for renal cell carcinoma (RCC). We conducted a meta-analysis of two new scans of 5,198 cases and 7,331 controls together with four existing ...
    • High volumes of recent surgical admissions, time to surgery, and 60-day mortality 

      Nilsen, Sara Marie; Asheim, Andreas; Carlsen, Fredrik; Anthun, Kjartan Sarheim; Johnsen, Lars Gunnar; Vatten, Lars Johan; Bjørngaard, Johan Håkon (Peer reviewed; Journal article, 2021)
      Few studies have investigated potential consequences of strained surgical resources. The aim of this cohort study was to assess whether a high proportion of concurrent acute surgical admissions, tying up hospital surgical ...
    • High ward occupancy, bedspacing, and 60 day mortality for patients with myocardial infarction, stroke, and heart failure 

      Asheim, Andreas; Nilsen, Sara Marie; Aam, Stina; Anthun, Kjartan Sarheim; Carlsen, Fredrik; Janszky, Imre; Vatten, Lars Johan; Bjørngaard, Johan Håkon (Journal article; Peer reviewed, 2022)
      Abstract Aims To study the consequences of crowded wards among patients with cardiovascular disease. Methods and results This is a cohort study among 201 801 patients with 258 807 admissions who were acutely admitted for ...
    • Hormone therapy use and mammographic density in postmenopausal Norwegian women 

      Couto, Elisabeth; Qureshi, Samera Azeem; Hofvind, Solveig; Hilsen, Marit; Aase, Hildegunn Siv; Skaane, Per; Vatten, Lars Johan; Ursin, Giske (Journal article; Peer reviewed, 2012)
    • Hospitals' Discharge Tendency and Risk of Death - An Analysis of 60,000 Norwegian Hip Fracture Patients 

      Nilsen, Sara Marie; Bjørngaard, Johan Håkon; Carlsen, Fredrik; Anthun, Kjartan Sarheim; Johnsen, Lars Gunnar; Vatten, Lars Johan; Asheim, Andreas (Peer reviewed; Journal article, 2020)
      Purpose: A reduction in the length of hospital stay may threaten patient safety. This study aimed to estimate the effect of organizational pressure to discharge on 60-day mortality among hip fracture patients. Patients ...
    • How do busy hospital circumstances affect mortality and readmission within 60 days: A cohort study of 680 000 acute admissions in Norway 

      Nilsen, Sara Marie; Asheim, Andreas; Carlsen, Fredrik; Anthun, Kjartan Sarheim; Vatten, Lars Johan; Aam, Stina; Davies, Neil Martin; Bjørngaard, Johan Håkon (Peer reviewed; Journal article, 2022)
      Objective To study mortality and readmissions for older patients admitted during more and less busy hospital circumstances. Design Cohort study where we identified patients that were admitted to the same hospital, ...
    • Hypertension and the risk of endometrial cancer: A systematic review and meta-analysis of case-control and cohort studies 

      Aune, Dagfinn; Sen, Abhijit; Vatten, Lars Johan (Journal article; Peer reviewed, 2017)
      A history of hypertension has been associated with increased risk of endometrial cancer in several studies, but the results have not been consistent. We conducted a systematic review and meta-analysis of case-control and ...
    • Hypertension in Pregnancy and Offspring Cardiovascular Risk in Young Adulthood: Prospective and Sibling Studies in the HUNT Study (Nord-Trøndelag Health Study) in Norway 

      Alsnes, Ingvild Vatten; Vatten, Lars Johan; Fraser, Abigail; Bjørngaard, Johan Håkon; Rich-Edwards, Janet Wilson; Romundstad, Pål Richard; Åsvold, Bjørn Olav (Journal article; Peer reviewed, 2017)
      Women with hypertensive disorders in pregnancy are at increased lifetime risk for cardiovascular disease. We examined the offspring’s cardiovascular risk profile in young adulthood and their siblings’ cardiovascular risk ...
    • Impact of MDM2 promoter SNP55 (rs2870820) on risk of endometrial and ovarian cancer 

      Helwa, Reham; Gansmo, Liv Beathe; Bjørnslett, Merete Pauline; Halle, Mari Kyllesø; Werner, Henrica Maria Johanna; Romundstad, Pål Richard; Hveem, Kristian; Vatten, Lars Johan; Dørum, Anne; Lønning, Per Eystein; Knappskog, Stian (Journal article; Peer reviewed, 2021)
      Background While large GWAS analyses have not found convincing associations between MDM2 promoter SNP55 and gynaecological cancers, SNP55 is in linkage disequilibrium with two other functional SNPs in the same promoter, ...
    • Impact of the APOBEC3A/B deletion polymorphism on risk of ovarian cancer 

      Gansmo, Liv Beathe; Sofiyeva, Nigar; Bjørnslett, Merete Pauline; Romundstad, Pål Richard; Hveem, Kristian; Vatten, Lars Johan; Dørum, Anne; Lønning, Per Eystein; Knappskog, Stian (Journal article; Peer reviewed, 2021)
      A germline 29.5-kb deletion variant removes the 3’ end of the APOBEC3A gene and a large part of APOBEC3B, creating a hybrid gene that has been linked to increased APOBEC3 activity and DNA damage in human cancers. We genotyped ...
    • Influence of common genetic variation on lung cancer risk: meta-analysis of 14 900 cases and 29 485 controls 

      Timofeeva, M N; Hung, R J; Rafnar, T; Christiani, D C; Field, J K; Bickeboller, H; Risch, A; McKay, J D; Wang, Y; Dai, J; Gaborieau, V; McLaughlin, J; Brenner, D; Narod, S A; Caporaso, NE.; Albanes, D; Thun, M; Eisen, T; Wichmann, H E; Rosenberger, A; Han, Y; Chen, W; Zhu, D; Spitz, M; Wu, X; Pande, M; Zhao, Y; Zaridze, D; Szeszenia-Dabrowska, N; Lissowska, J; Rudnai, P; Fabianova, E; Mates, D; Bencko, V; Foretova, L; Janout, V; Krokan, Hans Einar; Gabrielsen, Maiken Elvestad; Skorpen, Frank; Vatten, Lars Johan; Njølstad, Inger; Chen, C; Goodman, G; Lathrop, M; Benhamou, S; Vooder, T; Valk, K; Nelis, M; Metspalu, Andres; Raji, O; Chen, Y; Gosney, J; Liloglou, T; Muley, T; Dienemann, H; Thorleifsson, G; Shen, H.; Stefansson, Kari; Brennan, Paul; Amos, C I; Houlston, Richard; Landi, M T (Journal article; Peer reviewed, 2012)
    • Influence of MDM2 SNP309 and SNP285 status on the risk of cancer in the breast, prostate, lung and colon 

      Gansmo, Liv Beathe; Knappskog, Stian; Romundstad, Pål Richard; Hveem, Kristian; Vatten, Lars Johan; Lønning, Per Eystein (Journal article; Peer reviewed, 2015)
      MDM2 is a key regulator of the p53 tumor suppressor protein and is overexpressed in many human cancers. Two single nucleotide polymorphisms (SNPs) located in the MDM2 intronic promoter (P2) have been found to exert biological ...
    • Insomnia and Endothelial Function - The HUNT 3 Fitness Study 

      Strand, Linn B.; Laugsand, Lars E.; Skaug, Eli-Anne; Ellingsen, Øyvind; Madssen, Erik; Wisløff, Ulrik; Vatten, Lars Johan; Janszky, Imre (Journal article; Peer reviewed, 2012)
      Background: Insomnia is associated with increased risk of coronary heart disease (CHD), but the underlying mechanisms are not understood. To our knowledge, no previous studies have examined insomnia in relation to endothelial ...
    • Interpreting Breast Cancer Mortality Trends Related to Introduction of Mammography Screening: A Simulation Study 

      Heggland, Torunn; Vatten, Lars Johan; Opdahl, Signe; Weedon-Fekjær, Harald (Peer reviewed; Journal article, 2022)
      Background. Several studies have evaluated the effect of mammography screening on breast cancer mortality based on overall breast cancer mortality trends, with varied conclusions. The statistical power of such trend analyses ...
    • Invasive lobular breast cancer: The prognostic impact of histopathological grade, E-cadherin and molecular subtypes 

      Engstrøm, Monica J; Opdahl, Signe; Vatten, Lars Johan; Haugen, Olav Anton; Bofin, Anna M. (Peer reviewed; Journal article, 2015)
      Aims The aim of this study was to compare breast cancer specific survival (BCSS) for invasive lobular carcinoma (ILC) and invasive ductal carcinoma (IDC) and, further, to evaluate critically the prognostic value of ...
    • Life Course Trajectories of Cardiovascular Risk Factors in Women With and Without Hypertensive Disorders in First Pregnancy: The HUNT Study in Norway 

      Haug, Eirin; Horn, Julie; Markovitz, Amanda Rose; Fraser, Abigail; Vatten, Lars Johan; Macdonald-Wallis, Corrie; Tilling, Kate; Romundstad, Pål Richard; Rich-Edwards, Janet Wilson; Åsvold, Bjørn Olav (Journal article; Peer reviewed, 2018)
      Background: Women with hypertensive pregnancy disorders have adverse levels of cardiovascular risk factors. It is unclear how this adverse risk factor profile evolves during adult life. We compared life course trajectories ...
    • Life course trajectories of Maternal Cardiovascular Risk Factors according to Offspring Birthweight: The HUNT Study 

      Horn, Julie; Haug, Eirin Beate; Markovitz, Amanda R; Fraser, Abigail; Vatten, Lars Johan; Romundstad, Pål Richard; Rich-Edwards, Janet W.; Åsvold, Bjørn Olav (Peer reviewed; Journal article, 2020)
      Women with small or large for gestational age offspring are at increased risk of cardiovascular disease later in life. How their cardiovascular risk factors develop across the life course is incompletely known. We linked ...
    • Light-moderate alcohol consumption and left ventricular function among healthy, middle-aged adults: the HUNT study 

      Gemes, Katalin; Janszky, Imre; Strand, Linn B; László, Krisztina D.; Ahnve, Staffan; Vatten, Lars Johan; Dalen, Håvard; Mukamal, Kenneth J (Journal article; Peer reviewed, 2018)
      Objectives To investigate the association between alcohol consumption and left ventricular (LV) function in a population with low average alcohol intake. Design, setting and participants A total of 1296 healthy participants, ...