Browsing NTNU Open by Author "Strand, Berit Løkensgard"
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Chemically modified alginates and chitosans Lateral and terminal functionalization by reductive amination
Dalheim, Marianne Øksnes (Doctoral theses at NTNU;2016:274, Doctoral thesis, 2016)ENGLISH: Polysaccharides with added functions and/or modified properties are of increasing interest in preparing new materials suitable for both industrial applications and more advanced applications within biomedical ... -
Coating of alginate capsules
Hadjialirezaei, Soosan (Master thesis, 2013)Alginate is a popular candidate for encapsulation of cells due to the formation of gels with divalent ions under physiological conditions. Stable alginate gels can be formed by the selection of alginates with a high content ... -
Composite Hydrogels of Alginate and Cellulose Nanofibrils - A study of mechanical properties
Pedersen, Ina Sander (Master thesis, 2018)The main focus of this thesis was to attain more information about how alginate - CNF composite hydrogels are affected by each of the two polysaccharides, in order to gain additional knowledge which could be used to ... -
Composite PACA Nanoparticle-Alginate Microspheres for Sustained Drug Delivery - Characterization, Optimization, In Vitro Drug Release and Cytotoxicity Studies
Einen, Caroline; Benjakul, Sopisa (Master thesis, 2018) -
Culture of hESC-derived pancreatic progenitors in alginate-based scaffold
Formo, Kjetil Ødegård; Cho, Candy H-H; Vallier, Ludovic; Strand, Berit Løkensgard (Journal article; Peer reviewed, 2015)The effect of alginate-based scaffolds with added basement membrane proteins on the in vitro development of hESC-derived pancreatic progenitors was investigated. Cell clusters were encapsulated in scaffolds containing the ... -
Current and Future Perspectives on Alginate Encapsulated Pancreatic Islet
Strand, Berit Løkensgard; Coron, Abba Elizabeth; Skjåk-Bræk, Gudmund (Journal article; Peer reviewed, 2017)Transplantation of pancreatic islets in immune protective capsules holds the promise as a functional cure for type 1 diabetes, also about 40 years after the first proof of principal study. The concept is simple in using ... -
Degradation of Calcium Gels of Alginate and Periodate Oxidised Alginate
Marinho Carvalho Bjørge, Isabel (Master thesis, 2016)The extracellular matrix (ECM) functions as a structural scaffold for cells and controls cellular function through cell-matrix interactions. These interactions are required by most cells in order to maintain viable and ... -
Development of a perfused 3D cell culture system using alginate microbeads
Bergendahl, Kristin Gjulem (Master thesis, 2022)Abstract will be available on 2025-05-31 -
Disulfide-crosslinked alginate hydrogels functionalized with bioactive peptides for cell cultivation
Rian, Elise Helene Skattem (Master thesis, 2021)Hydrogeler av alginat er biokompatible og har lav immunologisk profil, noe som gjør dem attraktive for cellekultivering. På tross av disse ønskede egenskapene, vil alginat i seg selv ikke støtte viktige cellulære funksjoner ... -
Efficient functionalization of alginate biomaterials
Dalheim, Marianne Øksnes; Vanacker, Julie; Najmi, Maryam A.; Aachmann, Finn Lillelund; Strand, Berit Løkensgard; Christensen, Bjørn E. (Journal article; Peer reviewed, 2016)Peptide coupled alginates obtained by chemical functionalization of alginates are commonly used as scaffold materials for cells in regenerative medicine and tissue engineering. We here present an alternative to the commonly ... -
Efficient Grafting of Cyclodextrin to Alginate and Performance of the Hydrogel for Release of Model Drug
Omtvedt, Line Aanerud; Dalheim, Marianne Øksnes; Nielsen, Thorbjørn T.; Larsen, Kim; Strand, Berit Løkensgard; Aachmann, Finn Lillelund (Journal article; Peer reviewed, 2019)Controlling the rate of release of molecules from a hydrogel is of high interest for various drug delivery systems and medical devices. A strategy to alter the release profiles of soluble and poorly soluble active ingredients ... -
Encapsulation boosts islet-cell signature in differentiating human induced pluripotent stem cells via integrin signalling
Legøy, Thomas Aga; Vethe, Heidrun; Abadpour, Shadab; Strand, Berit Løkensgard; Scholz, Hanne; Paulo, Joao A.; Ræder, Helge; Ghila, Luiza; Chera, Simona (Peer reviewed; Journal article, 2020)Cell replacement therapies hold great therapeutic potential. Nevertheless, our knowledge of the mechanisms governing the developmental processes is limited, impeding the quality of differentiation protocols. Generating ... -
Establishing robust 2D cultures of killer whale primary cells: an optimization study
Hoven, Sigrid Setsaas (Master thesis, 2023)Norske spekkhoggere (Orcinus orca) er som følge av deres trofiske nivå og føde blant de mest kontaminerte marine pattedyrene i verden. Akkumulering av persistente organiske forbindelser (POPs) kan føre til forstyrrelser ... -
Evaluation of modified alginates for encapsulation of hPSC-derived Hepatocyte-like cells
Kringstad, Vera Idadatter (Master thesis, 2020)Intraperitoneal transplantasjon av alginatinnkapslede humane hepatocytter er en lovende metode for å assistere ved akutt leversvikt, som et alternativ til invasiv levertransplantasjon. Å bruke hepatocyttlignende celler ... -
Evaluation og hPSCs-derived Hepatocyte-like cells in native and modified alginates
Mathisen, Anna Nora Sandborg (Master thesis, 2020)Dette arbeidet studerer det terapeutiske potensialet til hepatocytt-liknende celler (HLC-er) generert fra humane pluripotente stamceller ved en ny metode kalt "forward programming" (FoP). Knappheten av tilgjengelige levere ... -
Explorations of in vitro models for new understanding of the host-material response
Kjærnsmo, Fredrikke (Master thesis, 2020)Celleinnkapslingteknologi benytter biomaterialer for transplantasjon av celler og viser potensiale som et terapeutisk alternativ til behandling av diabetes type 1. Fagfeltet har kommet langt i utviklingen av kapsler for ... -
Formation of Hydroxyapatite via Transformation of Amorphous Calcium Phosphate in the Presence of Alginate Additives
Ucar, Seniz; Bjørnøy, Sindre Hove; Bassett, David; Strand, Berit Løkensgard; Sikorski, Pawel; Andreassen, Jens-Petter (Journal article; Peer reviewed, 2019)Hydroxyapatite (HA) is the primary mineral of vertebral tooth and bone tissue; thus, it is often incorporated into synthetic composite materials designed for hard tissue engineering applications. Understanding the formation ... -
Functionalization of alginate gels using G-block end-modification
Scott, Sara (Master thesis, 2019)Alginat er lineære co-polymerer bestående av (1-4)-linket beta-D-mannuronsyre (M) og dets C5 epimer alpha-L-guluronsyre (G). Monomerene kan eksistere som homopolymeriske blokker (Mblokker eller G-blokker) eller som ... -
Gel Beads of Alginate from Laminaria Hyperborea Leaf - Stability related to size and polymer distribution
Coron, Abba Elizabeth (Master thesis, 2015)Alginate microbeads have through many years of research shown great potential as an immunoisolation system for the entrapment of insulin-producing cells. However, one of the main challenges in the use of alginate gels as ... -
Gelling kinetics and in situ mineralization of alginate hydrogels: A correlative spatiotemporal characterization toolbox.
Åslund, Andreas; Bassett, David; Ucar, Seniz; Sikorski, Pawel; Andreassen, Jens-Petter; Mandaric, Stefan; Bjørnøy, Sindre Hove; Strand, Berit Løkensgard (Journal article; Peer reviewed, 2016)Due to their large water content and structural similarities to the extracellular matrix, hydrogels are an attractive class of material in the tissue engineering field. Polymers capable of ionotropic gelation are of special ...