Blar i NTNU Open på forfatter "Solligård, Erik"
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Incidence, recurring admissions and mortality of severe bacterial infections and sepsis over a 22-year period in the population-based HUNT study
Liyanarachi, Kristin Vardheim; Solligård, Erik; Mohus, Randi Marie; Åsvold, Bjørn Olav; Rogne, Tormod; Damås, Jan Kristian (Peer reviewed; Journal article, 2022)Purpose Severe bacterial infections are important causes of hospitalization and loss of health worldwide. In this study we aim to characterize the total burden, recurrence and severity of bacterial infections in the ... -
Insomnia symptoms and risk of bloodstream infections: prospective data from the prospective population-based Nord-Trøndelag Health Study (HUNT), Norway
Thorkildsen, Marianne Thorkildsen; Laugsand, Lars Erik; Nilsen, Tom Ivar Lund; Mohus, Randi Marie; Hovik, Lise; Rogne, Tormod; Solligård, Erik; Damås, Jan Kristian; Gustad, Lise Tuset (Journal article; Peer reviewed, 2022) -
Iron and sex matter in severe infections Epidemiological studies of bloodstream infections, sepsis and COVID-19
Mohus, Randi Marie (Doctoral theses at NTNU;2022:360, Doctoral thesis, 2022) -
Iron status and the risk of sepsis and severe COVID-19: a two-sample Mendelian randomization study
Mohus, Randi Marie; Flatby, Helene Marie; Liyanarachi, Kristin Vardheim; DeWan, Andrew T.; Solligård, Erik; Damås, Jan Kristian; Åsvold, Bjørn Olav; Gustad, Lise Tuset; Rogne, Tormod (Journal article; Peer reviewed, 2022) -
Long-term temporal trends in incidence rate and case fatality of sepsis and COVID-19-related sepsis in Norwegian hospitals, 2008-2021: a nationwide registry study
Skei, Nina Vibeche; Nilsen, Tom Ivar Lund; Knoop, Siri Tandberg; Prescott, Hallie; Lydersen, Stian; Mohus, Randi Marie; Brkic, Alen; Liyanarachi, Kristin Vardheim; Solligård, Erik; Damås, Jan Kristian; Gustad, Lise Tuset (Peer reviewed; Journal article, 2023)Objectives To estimate temporal trends in incidence rate (IR) and case fatality during a 14-year period from 2008 to 2021, and to assess possible shifts in these trends during the COVID-19 pandemic. Setting All Norwegian ... -
Mapping the human genetic architecture of COVID-19
Niemi, Mari E.K.; Karjalainen, Juha; Liao, Rachel G.; Neale, Benjamin M.; Daly, Mark; Ganna, Andrea; Pathak, Gita A.; Andrews, Shea J.; Kanai, Masahiro; Veerapen, Kumar; Fernandez-Cadenas, Israel; Schulte, Eva C.; Striano, Pasquale; Afset, Jan Egil; Solligård, Erik; Damås, Jan Kristian; Risnes, Kari; Bettini, Laura Rachele; Gustad, Lise Tuset; Holter, Jan Cato; Hov, Johannes Espolin Roksund; Karlsen, Tom Hemming; Folseraas, Trine; Holten, Aleksander Rygh; Dyrhol-Riise, Anne Ma; Tonby, Kristian; Lind, Andreas; Müller, Fredrik; Dudman, Susanne Gjeruldsen; Grimsrud, Marit Mæhle; Vadla, May Sissel; Myhre, Ronny; Kildal, Anders Benjamin; Hoff, Dag Arne Lihaug; Muller, Karl Erik; Heggelund, Lars; Bergan, Jonas; Skogen, Vegard (Journal article; Peer reviewed, 2021)The genetic make-up of an individual contributes to the susceptibility and response to viral infection. Although environmental, clinical and social factors have a role in the chance of exposure to SARS-CoV-2 and the severity ... -
Monitoring quality of care for peripheral intravenous catheters; feasibility and reliability of the peripheral intravenous catheters mini questionnaire (PIVC-miniQ)
Høvik, Lise Husby; Gjeilo, Kari Hanne; Lydersen, Stian; Rickard, Claire; Røtvold, Benedikte; Damås, Jan Kristian; Solligård, Erik; Gustad, Lise (Journal article; Peer reviewed, 2019)Background Peripheral intravenous catheters (PIVCs) account for a mean of 38% of catheter associated bloodstream infections (CABSI) with Staphylococcus aureus, which are preventable if deficiencies in best practice are ... -
Non-communicable diseases at a regional hospital in Nepal: Findings of a high burden of alcohol-related disease
Amundsen, Marie S.; Kirkeby, Tine Marita Gjervan; Giri, Samita; Koju, R; Krishna, SS; Ystgaard, Brynjulf; Solligård, Erik; Risnes, Kari (Peer reviewed; Journal article, 2016)Recent global burden of disease reports find that a major proportion of global deaths and disability worldwide can be attributed to alcohol use. Thus, it may be surprising that very few studies have reported on the burden ... -
Pediatric Patients in a Local Nepali Emergency Department: Presenting Complaints, Triage and Post-Discharge Mortality
Giri, Samita; Halvas-Svendsen, Tine; Rogne, Tormod; Shrestha, Sanu Krishna; Døllner, Henrik; Solligård, Erik; Risnes, Kari (Peer reviewed; Journal article, 2020)Background. In low-income countries, pediatric emergency care is largely underdeveloped although child mortality in emergency care is more than twice that of adults, and mortality after discharge is high. Aim. We aimed at ... -
Pharmacologic and Genetic Downregulation of Proprotein Convertase Subtilisin/Kexin Type 9 and Survival from Sepsis
Lawler, Patrick R.; Manvelian, Garen; Coppi, Alida; Damask, Amy; Cantor, Michael N.; Ferreira, Manuel A. R.; Paulding, Charles; Banerjee, Nilanjana; Li, Dadong; Jorgensen, Susan; Attre, Richa; Carey, David J.; Krebs, Kristine; Milani, Lili; Hveem, Kristian; Damås, Jan Kristian; Solligård, Erik; Stender, Stefan; Tybjærg-Hansen, Anne; Nordestgaard, Børge G.; Hernandez-Beeftink, Tamara; Rogne, Tormod; Flores Perez, Carlos Antonio; Villar, Jesús; Walley, Keith R.; Liu, Vincent X.; Fohner, Alison E.; Lotta, Luca A.; Kyratsous, Christos A.; Sleeman, Mark W.; Scemama, Michel; Delgizzi, Richard; Pordy, Robert; Horowitz, Julie E.; Baras, Aris; Martin, Greg S.; Steg, Philippe Gabriel; Schwartz, Gregory G.; Szarek, Michael; Goodman, Shaun G. (Peer reviewed; Journal article, 2023)OBJECTIVES: Treatments that prevent sepsis complications are needed. Circulating lipid and protein assemblies—lipoproteins play critical roles in clearing pathogens from the bloodstream. We investigated whether early ... -
Poor performance of quick-SOFA (qSOFA) score in predicting severe sepsis and mortality: a prospective study of patients admitted with infection to the emergency department
Askim, Åsa Susanne; Moser, Florentin; Gustad, Lise; Stene, Helga; Gundersen, Maren; Åsvold, Bjørn Olav; Dale, Jostein; Bjørnsen, Lars Petter Bache-Wiig; Damås, Jan Kristian; Solligård, Erik (Journal article; Peer reviewed, 2017)Background We aimed to evaluate the clinical usefulness of qSOFA as a risk stratification tool for patients admitted with infection compared to traditional SIRS criteria or our triage system; the Rapid Emergency Triage ... -
Presenting complaints and mortality in a cohort of 22 000 adult emergency patients at a local hospital in Nepal
Giri, Samita; Rogne, Tormod; Uleberg, Oddvar; Skovlund, Eva; Shrestha, Sanu Krishna; Koju, Rajendra; Damås, Jan Kristian; Solligård, Erik; Risnes, Kari R (Journal article; Peer reviewed, 2019)Background There is a need to develop sustainable emergency health care systems in low-resource settings, but data that analyses emergency health care needs in these settings are scarce. We aimed at assessing presenting ... -
Prior statin use and 90-day mortality in Gram-negative and Gram-positive bloodstream infection: a prospective observational study
Mehl, Arne; Harthug, Stig; Lydersen, Stian; Paulsen, Julie; Åsvold, Bjørn Olav; Solligård, Erik; Damås, Jan Kristian; Edna, Tom-Harald (Journal article; Peer reviewed, 2014)n several studies on patients with bloodstream infection (BSI), prior use of statins has been associated with improved survival. Gram-positive and Gram-negative bacteria alert the innate immune system in different ways. ... -
Risk and prognosis of bloodstream infections: The influence of obesity and lifestyle, genetic variation, and clinical factors present at the time of infection: The HUNT study and the Nord-Trøndelag Bacteremia registry
Paulsen, Julie (Doctoral theses at NTNU;2018:169, Doctoral thesis, 2018)Risiko og prognose ved blodbaneinfeksjoner: Effekt av fedme og livsstil, genetiske varianter og kliniske faktorer i forbindelse med infeksjon. HUNT-studien og Nord-Trøndelag bakteriemiregister Blodbaneinfeksjoner og sepsis ... -
Risk of lower respiratory tract infections: a genome-wide association study with Mendelian randomization analysis in three independent European populations
Flatby, Helene Marie; Rasheed, Humaira; Ravi, Anuradha; Thomas, Laurent; Liyanarachi, Kristin Vardheim; Afset, Jan Egil; DeWan, Andrew; Brumpton, Ben Michael; Hveem, Kristian; Åsvold, Bjørn Olav; Simonsen, Gunnar Skov; Furberg, Anne-Sofie; Damås, Jan Kristian; Solligård, Erik; Rogne, Tormod (Journal article; Peer reviewed, 2021)Objective: Lower respiratory tract infections (LRTIs) are a leading cause of morbidity and mortality worldwide. Few studies have previously investigated the genetic susceptibility and potential risk factors for LRTI. ... -
Risk of severe infections: The effect of modifiable risk factors and genetic variations
Flatby, Helene Marie (Doctoral theses at NTNU;2023:138, Doctoral thesis, 2023)Severe infections are common causes of hospitalization, morbidity, and mortality worldwide. It is important to improve our understanding of why some individuals are more susceptible to severe infections than others. ... -
Samstilling av sensordata, sykepleiedokumentasjon og virkeligheten for intensivpasienter: - Et observasjonsstudium.
Gundersen, Ørjan (Master thesis, 2018)Helsevesenet tar nå i bruk nye digitale systemer for automatisk lagring av sensordata og avansert rapportering av pasientdata. En utfordring er imidlertid mangelen på validering av slike data, det vil si i hvilken grad ... -
SARS-CoV-2 Nsp13 encodes for an HLA-E-stabilizing peptide that abrogates inhibition of NKG2A-expressing NK cells
Hammer, Quirin; Dunst, Josefine; Christ, Wanda; Picarazzi, Francesca; Wendorff, Mareike; Momayyezi, Pouria; Huhn, Oisín; Netskar, Herman Krogstad; Maleki, Kimia T.; García, Marina; Sekine, Takuya; Sohlberg, Ebba; Azzimato, Valerio; Aouadi, Myriam; Holten, Aleksander Rygh; Kildal, Anders Benjamin; Lind, Andreas; Dyrhol-Riise, Anne Ma; Hoff, Dag Arne Lihaug; Solligård, Erik; Holter, Jan Cato; Afset, Jan Egil; Damås, Jan Kristian; Hov, Johannes Espolin Roksund; Bergan, Jonas; Risnes, Kari; Muller, Karl Erik; Tonby, Kristian; Heggelund, Lars; Gustad, Lise Tuset; Grimsrud, Marit Mæhle; Vadla, May Sissel; Lenning, Ole Bernt; Myhre, Ronny; Haider, Sammra; Dudman, Susanne Gjeruldsen; Karlsen, Tom Hemming; Folseraas, Trine; Skogen, Vegard; Degenhardt, Frauke; Franke, Andre; Spallotta, Francesco; Mori, Mattia; Michaëlsson, Jakob; Björkström, Niklas K.; Rückert, Timo; Romagnani, Chiara; Horowitz, Amir; Klingström, Jonas; Ljunggren, Hans-Gustaf; Malmberg, Karl-Johan (Peer reviewed; Journal article, 2022)Natural killer (NK) cells are innate immune cells that contribute to host defense against virus infections. NK cells respond to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in vitro and are activated in ... -
Sepsis i akuttmottaket ved St. Olavs Hospital - En retrospektiv analyse av behandlingsforløp og håndtering av pasienter med sepsis
Gundersen, Maren; Stene, Helga (Master thesis, 2015)Bakgrunn: Sepsis er en vanlig problemstilling i sykehus verden over, og flere studier har vist at insidensen er økende. På grunn av framgang i diagnostikk og behandling har mortaliteten ved sepsis gått ned, men den er ... -
Staphylococcus aureus-endokarditt ved St.Olavs hospital 2013-2018: epidemiologi og perifere venekatetres rolle
Djuve, Mari Brekke (Master thesis, 2021)Bakgrunn Staphylococcus aureus-endokarditt er en alvorlig sykdom med høy mortalitet. Perifere venekatetre kan være en inngangsport for denne infeksjonen. På grunn av den høye forekomsten av perifere venekatetre i klinisk ...