Blar i NTNU Open på forfatter "Røe, Oluf Dimitri"
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JWA regulates TRAIL-induced apoptosis via MARCH8-mediated DR4 ubiquitination in cisplatin-resistant gastric cancer cells
Wang, Q; Chen, Q; Zhu, L; Chen, M; Xu, W; Panday, S; Wang, Z; Li, A; Røe, Oluf Dimitri; Chen, R; Wang, S; Zhang, R; Zhou, J (Journal article; Peer reviewed, 2017)Platinum chemotherapeutics are widely used to treat solid malignant tumors, including gastric cancer (GC). Drug resistance to platinum compounds may result in cancer relapse and decreased survival. The identification and ... -
JWA reverses cisplatin resistance via the CK2-XRCC1 pathway in human gastric cancer cells
Xu, W; Chen, Q; Wang, Q; Sun, Y; Wang, S; Li, A; Xu, S; Røe, Oluf Dimitri; Wang, R; Zhang, R.; Yang, L; Zhou, J. (Journal article; Peer reviewed, 2014)Gastric cancer is the third most common malignancy in China, with a median 5-year survival of only 20%. Cisplatin has been used in first-line cancer treatment for several types of cancer including gastric cancer. However, ... -
Major durable response of pembrolizumab in chemotherapy refractory small cell bladder cancer: A case report
Nguyen, Olav Toai Duc; Sundstrøm, Stein Harald; Westvik, Ganna Surzhykova; Røttereng, Ane Karoline Stræte; Melhus, Mona Røli; Bergseth, Cecilie; Hallem, Elisabeth Kvelstad; Røe, Oluf Dimitri (Peer reviewed; Journal article, 2020)Small cell carcinoma of the urinary bladder is a rare subtype (incidence of 1–9/1,000,000), characterized by an aggressive behavior with early metastasis and poor prognosis. Chemotherapy, radiation, and surgery are the ... -
Malignant Mesothelioma: Virus, Biomarkers and Genes- a Translational Approach
Røe, Oluf Dimitri (Doktoravhandlinger ved NTNU, 1503-8181; 2008:275, Doctoral thesis, 2008)Malignant mesothelioma is an asbestos-related, lethal treatment resistant tumour with increasing incidence worldwide. In four translational studies we have studied the pathogenesis of mesothelioma with regard to the SV40 ... -
Malignant Mesothelioma: Virus, Biomarkers and Genes- a Translational Approach
Røe, Oluf Dimitri (Doktoravhandlinger ved NTNU, 1503-8181; 2008:275, Doctoral thesis, 2008)Malignant mesothelioma is an asbestos-related, lethal treatment resistant tumour with increasing incidence worldwide. In four translational studies we have studied the pathogenesis of mesothelioma with regard to the SV40 ... -
Malignant pleural mesothelioma: History, controversy and future of a manmade epidemic
Røe, Oluf Dimitri; Stella, Giulia Maria (Journal article; Peer reviewed, 2015)Asbestos is the term for a family of naturally occurring minerals that have been used on a small scale since ancient times. Industrialisation demanded increased mining and refining in the 20th century, and in 1960, Wagner, ... -
MDM2 is a useful prognostic biomarker for resectable gastric cancer
Ye, Yang; Li, Xuan; Yang, Jiangjing; Miao, Shuhan; Wang, Shouyu; Chen, Yansu; Xia, Xiaowei; Wu, Xuming; Zhang, Jianbing; Zhou, Yan; He, Song; Tan, YongFei; Qiang, FuLin; Li, Gang; Røe, Oluf Dimitri; Zhou, Jianwei (Journal article; Peer reviewed, 2013)Expression of MDM2 protein appears to be increased in malignancy and correlated to prognosis of tumors, but its role in gastric cancer remains controversial. Our recent investigations indicated that JWA was a novel candidate ... -
Molecular Resistance Fingerprint of Pemetrexed and Platinum in a Long-Term Survivor of Mesothelioma
Røe, Oluf Dimitri; Szulkin, Adam; Anderssen, Endre; Flatberg, Arnar; Sandeck, Helmut; Amundsen, Tore; Erlandsen, Sten Even; Dobra, Katalin; Sundstrøm, Stein Harald (Journal article; Peer reviewed, 2012) -
A nomogram to predict survival probability of gastric cancer patients undergoing radical surgery and adjuvant chemotherapy
Ma, Ling; Chen, Guosheng; Wang, Deqiang; Zhang, Kai; Zhao, Fengjiao; Tang, Jie; Zhao, Jianyi; Røe, Oluf Dimitri; He, Shaohua; Liao, Dongcheng; Gu, Yanhong; Tao, Min; Shu, Yongqian; Li, Wei; Chen, Xiaofeng (Peer reviewed; Journal article, 2022)Gastric cancer (GC) is the third-leading cause of cancer mortality worldwide. The aim of this study was to develop a nomogram that estimates 1-year, 3-year, and 5-year survival probability of GC patients after D2 gastrectomy ... -
Non-occupational exposure to asbestos is the main cause of malignant mesothelioma in women in North Jutland, Denmark
Panou, Vasiliki; Vyberg, Mogens; Meristoudis, Christos; Hansen, Johnni; Bøgsted, Martin; Omland, Øyvind; Weinreich, Ulla Møller; Røe, Oluf Dimitri (Peer reviewed; Journal article, 2019)Objectives Diffuse malignant mesothelioma (MM) is mainly caused by asbestos inhalation. The malignancy is rare among women and studies of the prevalence and causative role of non-occupational asbestos exposure among women ... -
Pankreaskreft. Insidens, utredning, behandling og overlevelse ved Helse Nord-Trøndelag 2010-2021
Gaupset, Lise (Master thesis, 2023)Introduksjon: Pankreaskreft er blant de mest dødelige kreftsykdommene på verdensbasis, og flesteparten av pasientene har fjernmetastaser ved diagnosetidspunktet. Få er kandidater til kirurgisk reseksjon, som er eneste ... -
Prognostic role of microscopically positive margins for primary gastrointestinal stromal tumors: a systematic review and meta-analysis
Zhi, Xiaofei; Jiang, Baofei; Yu, Junbo; Røe, Oluf Dimitri; Qin, Jun; Ni, Qingfeng; Sun, Luning; Xu, Meirong; Zhu, Jianwei; Ma, Lilin (Peer reviewed; Journal article, 2016)The impact and management of microscopically positive margins in gastrointestinal stromal tumors (GISTs) remain unclear. The aim of this study is to estimate the prognostic value of surgical margins for disease-free survival ... -
‘Reduced’ HUNT model outperforms NLST and NELSON study criteria in predicting lung cancer in the Danish screening trial
Røe, Oluf Dimitri; Markaki, Maria; Tsamardinos, Ioannis; Lagani, Vincenzo; Nguyen, Olav Toai Duc; Pedersen, Jesper Holst; Saghir, Zaigham; Ashraf, Haseem (Journal article; Peer reviewed, 2019)Hypothesis We hypothesise that the validated HUNT Lung Cancer Risk Model would perform better than the NLST (USA) and the NELSON (Dutch‐Belgian) criteria in the Danish Lung Cancer Screening Trial (DLCST). Methods The ... -
Synergistic Role between p53 and JWA: Prognostic and Predictive Biomarkers in Gastric Cancer
Liu, Xin; Wang, Shouyu; Xia, Xiaowei; Chen, Yansu; Zhou, Yan; Wu, Xuming; Zhang, Jianbing; He, Song; Tan, YongFei; Qiang, FuLin; Røe, Oluf Dimitri; Li, Gang; Zhou, Jianwei (Journal article; Peer reviewed, 2012)Expression of p53 appears to be correlated to prognosis in patients with malignancy, but its role in gastric carcinoma has remained controversial. Recently we reported that JWA, an ADP-ribosylation-like factor 6 interacting ... -
The associations of sitting time and physical activity on total and site-specific cancer incidence: Results from the HUNT study, Norway
Rangul, Vegar; Sund, Erik Reidar; Mork, Paul Jarle; Røe, Oluf Dimitri; Bauman, Adrian (Journal article; Peer reviewed, 2018)Background Sedentary behavior is thought to pose different risks to those attributable to physical inactivity. However, few studies have examined the association between physical activity and sitting time with cancer ... -
The undifferentiated carcinoma that became a melanoma: Re-biopsy of a cancer of an unknown primary site: a case report.
Røe, Oluf Dimitri; Wahl, Sissel Gyrid Freim (Journal article; Peer reviewed, 2017)Background Cancer of unknown primary site is still a demanding condition as it is per definition metastatic, with heterogeneous biological behavior, and it is often resistant to therapy. Cancer of unknown primary site ... -
TXNL1-XRCC1 pathway regulates cisplatin-induced cell death and contributes to resistance in human gastric cancer
Xu, W; Wang, S; Chen, Q; Zhang, Y; Ni, P; Wu, X; Zhang, J; Qiang, F; Li, A; Røe, Oluf Dimitri; Xu, S; Wang, M; Zhang, R.; Zhou, J. (Journal article; Peer reviewed, 2014)Cisplatin is a cytotoxic platinum compound that triggers DNA crosslinking induced cell death, and is one of the reference drugs used in the treatment of several types of human cancers including gastric cancer. However, ... -
WT1 Promotes Cell Proliferation in Non-Small Cell Lung Cancer Cell Lines Through Up-Regulating Cyclin D1 and p-pRb In Vitro and In Vivo
Xu, CH; Wu, C; Xia, Y; Zhong, ZP; Liu, Xiang; Xu, Jing; Cui, Fei; Chen, Bin; Røe, Oluf Dimitri; Li, AH; Chen, YJ (Journal article; Peer reviewed, 2013)The Wilms’ tumor suppressor gene (WT1) has been identified as an oncogene in many malignant diseases such as leukaemia, breast cancer, mesothelioma and lung cancer. However, the role of WT1 in non-small-cell lung cancer ...