Blar i NTNU Open på forfatter "Ness-Jensen, Eivind"
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The development and validation of a high-capacity serological assay for celiac disease
Klaasen, Rolf; Warren, David; Iversen, Rasmus; Bolstad, Nils; Andersen, Ina Lervåg; Mjønes, Patricia; Rønne, Elin; Lundin, Knut; Sollid, Ludvig Magne; Ness-Jensen, Eivind (Peer reviewed; Journal article, 2022)Background The aim of the present study was to develop and clinically validate a high-throughput assay for serum IgA and IgG antibodies against transglutaminase-2 (TG2) and to determine appropriate assay cut-offs for ... -
Development and validation of a risk prediction model for esophageal squamous cell carcinoma using cohort studies
Wang, Qiaoli; Ness-Jensen, Eivind; Santoni, Giola; Xie, Shaohua; Lagergren, Jesper (Peer reviewed; Journal article, 2021)INTRODUCTION: Esophageal squamous cell carcinoma (ESCC) carries a poor prognosis, but earlier tumor detection would improve survival. We aimed to develop and externally validate a risk prediction model based on exposure ... -
Effects of Obesity Surgery on Overall and Disease-Specific Mortality in a 5-Country Population-Based Study
Kauppila, Joonas H.; Tao, Wenjing; Santoni, Giola; von Euler-Chelpin, My; Lynge, Elsebeth; Tryggvadóttir, Laufey; Ness-Jensen, Eivind; Romundstad, Pål Richard; Pukkala, Eero; Lagergren, Jesper (Journal article; Peer reviewed, 2019)Background & Aims Bariatric surgery might reduce overall mortality from obesity. We investigated whether the survival times of patients who have had bariatric surgery are similar to those of the general population and are ... -
Endoscopic findings in patients with coeliac disease
Bostrøm, Stine; Uthaug, Lindis (Master thesis, 2023)Sammendrag Bakgrunn Cøliaki er en kronisk immunmediert tynntarmsykdom som forekommer hos genetisk disponerte individer ved eksponering for gluten. Cøliaki har en global prevalens mellom 0,6-1%. Cøliaki påvirker hovedsakelig ... -
Endoscopic findings in patients with coeliac disease
Bostrøm, Stine; Uthaug, Lindis (Master thesis, 2023)Sammendrag Bakgrunn Cøliaki er en kronisk immunmediert tynntarmsykdom som forekommer hos genetisk disponerte individer ved eksponering for gluten. Cøliaki har en global prevalens mellom 0,6-1%. Cøliaki påvirker hovedsakelig ... -
Endoscopy for Gastroesophageal Reflux Disease and Survival in Esophageal Adenocarcinoma
Holmberg, Dag; Ness-Jensen, Eivind; Mattsson, Fredrik; Lagergren, Jesper (Peer reviewed; Journal article, 2019)Gastroesophageal reflux disease (GERD) is a risk factor of esophageal adenocarcinoma (EAC) and the most common indication for upper gastrointestinal endoscopy. Yet, whether GERD or endoscopy practice influence survival in ... -
Epidemiology and prevention of oesophageal adenocarcinoma
Ness-Jensen, Eivind (Peer reviewed; Journal article, 2022)Oesophageal adenocarcinoma (OAC) develops from columnar metaplasia of the distal oesophagus, Barrett’s oesophagus (BO), secondary to chronic gastro-oesophageal reflux disease (GORD). In the present review, the stepwise ... -
Epidemiology of gastro-oesophageal reflux A prospective population-based cohort study: The HUNT study
Ness-Jensen, Eivind (Doktoravhandlinger ved NTNU, 1503-8181; 2014:69, Doctoral thesis, 2014)Introduction Heartburn and acid regurgitation are the characteristic gastro-oesophageal reflux symptoms (GORS). GORS are associated with reduced quality of life and increased risk of oesophageal adenocarcinoma. GORS are ... -
Gastroesophageal Reflux and Sleep Disturbances: A Bidirectional Association in a Population-Based Cohort Study, the HUNT Study
Lindam, Anna; Ness-Jensen, Eivind; Jansson, Catarina; Nordenstedt, Helena; Åkersted, Torbjørn; Hveem, Kristian; Lagergren, Jesper (Journal article; Peer reviewed, 2016)Study Objectives: To investigate the potentially bidirectional association between gastroesophageal reflux symptoms (GERS) and sleep disturbances/ insomnia disorders. Methods: We assessed the incidence of new-onset of ... -
Genome-wide analysis of 53,400 people with irritable bowel syndrome highlights shared genetic pathways with mood and anxiety disorders
Eijsbouts, Chris; Skogholt, Anne Heidi; Ness-Jensen, Eivind; Hveem, Kristian (Peer reviewed; Journal article, 2021)Irritable bowel syndrome (IBS) results from disordered brain–gut interactions. Identifying susceptibility genes could highlight the underlying pathophysiological mechanisms. We designed a digestive health questionnaire for ... -
Genome-wide analysis of 944 133 individuals provides insights into the etiology of haemorrhoidal disease
Zheng, Thenghao; Skogholt, Anne Heidi; Gabrielsen, Maiken Elvestad; Hveem, Kristian; Thomas, Laurent; Ness-Jensen, Eivind (Peer reviewed; Journal article, 2021)Objective Haemorrhoidal disease (HEM) affects a large and silently suffering fraction of the population but its aetiology, including suspected genetic predisposition, is poorly understood. We report the first genome-wide ... -
Genome-wide association study and meta-analysis in Northern European populations replicate multiple colorectal cancer risk loci
Tanskanen, Tomas; Van Den Berg, Linda; Välimäki, Niko; Aavikko, Mervi; Ness-Jensen, Eivind; Hveem, Kristian; Wettergren, Yvonne; Lindskog, Elinor Bexe; Tönisson, Neeme; Metspalu, Andres; Silander, Kaisa; Orlando, Giulia; Law, Philip J.; Tuupanen, Sari; Gylfe, Alexandra E.; Hänninen, Ulrika A.; Cajuso, Tatiana; Kondelin, Johanna; Sarin, Antti-Pekka; Pukkala, Eero; Jousilahti, Pekka; Salomaa, Veikko; Ripatti, Samuli; Palotie, Aarno; Järvinen, Heikki; Renkonen-Sinisalo, Laura; Lepistö, Anna; Böhm, Jan; Mecklin, Jukka-Pekka; Al-Tassan, Nada A.; Palles, Claire; Martin, Lynn; Barclay, Ella; Tenesa, Albert; Farrington, Susan M.; Timofeeva, Maria N.; Meyer, Brian F; Wakil, Salma M.; Campbell, Harry; Smith, Christopher G.; Idziaszczyk, Shelley; Maughan, Tim S.; Kaplan, Richard; Kerr, Rachel; Kerr, David; Buchanan, Daniel D.; Win, Aung K.; Hopper, John; Jenkins, Mark A.; Newcomb, Polly A.; Gallinger, Steve; Conti, David; Schumacher, Fredrick R.; Casey, Graham; Cheadle, Jeremy P.; Dunlop, Malcolm G.; Tomlinson, Ian P; Houlston, Richard S.; Palin, Kimmo; Aaltonen, Lauri (Journal article; Peer reviewed, 2018)Genome-wide association studies have been successful in elucidating the genetic basis of colorectal cancer (CRC), but there remains unexplained variability in genetic risk. To identify new risk variants and to confirm ... -
Helicobacter pylori in relation to asthma and allergy modified by abdominal obesity: The HUNT study in Norway
Ness-Jensen, Eivind; Langhammer, Arnulf; Hveem, Kristian; Lu, Yunxia (Journal article; Peer reviewed, 2019)Objective It is unknown whether the decreasing prevalence of H. pylori infections is associated with the increase in obesity and asthma and allergy. In this study, we assessed if obesity plays an intermediate role between ... -
Hospital Volume of Antireflux Surgery in Relation to Endoscopic and Surgical Re-interventions
Markar, Sheraz; Santoni, Giola; Maret-Ouda, John; Artama, Miia; Färkkilä, Martti; Lynge, Elsebeth; Pukkala, Eero; Ness-Jensen, Eivind; von Euler-Chelpin, My; Lagergren, Jesper (Journal article; Peer reviewed, 2020)Objective: To test the hypothesis that higher hospital volume decreases endoscopic and surgical re-intervention rates after antireflux surgery. Background: Antireflux surgery for gastro-esophageal reflux disease is ... -
Hypergastrinemia and mortality in gastric adenocarcinoma: a population-based cohort study, the HUNT study
Ness-Jensen, Eivind; Bringeland, Erling Audun; Mjønes, Patricia; Lagergren, Jesper; Grønbech, Jon Erik; Waldum, Helge; Fossmark, Reidar (Peer reviewed; Journal article, 2022)Purpose: Hypergastrinemia increases the risk of developing proximal gastric adenocarcinoma. However, it is unclear if hypergastrinemia affects the survival in patients with gastric adenocarcinoma. This study aimed to examine ... -
Hypergastrinemia is associated with an increased risk of gastric adenocarcinoma with proximal location: A prospective population-based nested case-control study
Ness-Jensen, Eivind; Bringeland, Erling Audun; Mattsson, Fredrik; Mjønes, Patricia; Lagergren, Jesper; Grønbech, Jon Erik; Waldum, Helge; Fossmark, Reidar (Peer reviewed; Journal article, 2020)The incidence of proximal gastric adenocarcinoma is increasing among younger adults. Rodent models have shown that hypergastrinemia causes carcinogenesis in the proximal stomach. The aim of our study was therefore to assess ... -
Incidence and mortality in upper gastrointestinal cancer after negative endoscopy for gastroesophageal reflux disease
Holmberg, Dag; Santoni, Giola; von Euler-Chelpin, My; Färkkilä, Martti; Kauppila, Joonas; Maret-Ouda, John; Ness-Jensen, Eivind; Lagergren, Jesper (Peer reviewed; Journal article, 2021)Background and Aims Gastroesophageal reflux disease (GERD) is associated with an increased risk of cancer of the upper gastrointestinal tract. This study aimed to assess whether and to what extent a negative upper endoscopy ... -
Intramural gastrisk abscess
Bergersen, Silje; Holden, Hans Martin; Brenna, Øystein; Ness-Jensen, Eivind (Peer reviewed; Journal article, 2022) -
Is empiric proton pump inhibition in patients with symptoms of extraesophageal gastroesophageal reflux justified?
Fossmark, Reidar; Ness-Jensen, Eivind; Sørdal, Øystein Finset (Peer reviewed; Journal article, 2023)Background The prevalence of gastroesophageal reflux disease (GERD) has had a marked increase in Western countries with a paralleling interest in extraesophageal (EE) manifestations of GERD, including laryngopharyngeal ... -
Is empiric proton pump inhibition in patients with symptoms of extraesophageal gastroesophageal reflux justified?
Fossmark, Reidar; Ness-Jensen, Eivind; Sørdal, Øystein Finset (Peer reviewed; Journal article, 2023)Background The prevalence of gastroesophageal reflux disease (GERD) has had a marked increase in Western countries with a paralleling interest in extraesophageal (EE) manifestations of GERD, including laryngopharyngeal ...