Blar i NTNU Open på forfatter "Lindgren, Mikael"
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Kinetic effects in singlet oxygen mediated oxidations by immobilized photosensitizers on silica
Lancel, Maxime; Lindgren, Mikael; Monnereau, Cyrille; Amara, Zacharias (Peer reviewed; Journal article, 2023) -
Localization of Novel Chlorin Photosensitizers and Commercial Stains in the AY-27 Cell Model Using Advanced Fluorescence Microscopy
Bergvoll, Johannes Kjeldsen (Master thesis, 2021)Gjennom et samarbeid mellom Linköping Universitet og Norges Tekniske og Naturvitenskapelige Universitet, har flere nye kloriner for bruk i fotodynamisk terapi blitt syntetisert. To av disse klorinene, KA20-11H og KA20-11H-proto ... -
Luminescent Eu3+-doped NaLa(WO4)(MoO4) and Ba2CaMoO6 prepared by the modified Pechini method
Sletnes, Malin; Skjærvø, Susanne Linn; Lindgren, Mikael; Grande, Tor; Einarsrud, Mari-Ann (Journal article; Peer reviewed, 2016)Modified Pechini synthesis routes were developed for synthesis of the novel red phosphor materials NaLa(WO4)(MoO4):Eu3+ and Ba2CaMoO6:Eu3+. Phase pure NaLa(WO4)(MoO4):Eu3+ was obtained at calcination temperatures ≥600 °C ... -
Nanoscale Structure and Spectroscopic Probing of Aβ1-40 Fibril Bundle Formation
Psonka-Antonczyk, Katarzyna Maria; Hammarström, Per; Johansson, Leif B. G.; Lindgren, Mikael; Stokke, Bjørn Torger; Nilsson, K. Peter R.; Nyström, Sofie (Peer reviewed; Journal article, 2016)Amyloid plaques composed of fibrillar Amyloid-β (Aβ) are hallmarks of Alzheimer's disease. However, Aβ fibrils are morphologically heterogeneous. Conformation sensitive luminescent conjugated oligothiophenes (LCOs) are ... -
Nanoscopic and Photonic Ultrastructural Characterization of Two Distinct Insulin Amyloid States
Psonka-Antonczyk, Katarzyna Maria; Duboisset, Julien; Stokke, Bjørn Torger; Zako, Tamotsu; Kobayashi, Takahiro; Maeda, Mizuo; Nyström, Sofie; Mason, Jeffrey; Hammarström, Per; Nilsson, K. Peter R.; Lindgren, Mikael (Journal article; Peer reviewed, 2012)Two different conformational isoforms or amyloid strains of insulin with different cytotoxic capacity have been described previously. Herein these filamentous and fibrillar amyloid states of insulin were investigated using ... -
Octoxy capped Si nanoparticles synthesized by homogeneous reduction of SiCl4 with crown ether alkalide
Sletnes, Malin; Jerome, Maria; Grande, Tor; Lindgren, Mikael; Einarsrud, Mari-Ann (Journal article; Peer reviewed, 2014)Blue-green luminescent octoxy capped Si nanoparticles were synthesized via homogeneous reduction of SiCl4 with the crown ether alkalide K+(15-crown-5)2K− in tetrahydrofuran. The Si nanoparticles were characterized with ... -
Photodynamic Therapy with Novel Glycosylated Chlorin Complexes on Bladder Cancer Cells from Rat (AY-27) and Human (T-24)
Hageberg, Ingvild Uri (Master thesis, 2021)Formålet med dette masterprosjektet var å utforske fotodynamiske, fotofysiske og fotokjemiske egenskaper til noen nye glykosylerte kloriner. Dette prosjektet er en del av et pågående samarbeid mellom Institutt for fysikk, ... -
Photosensitizing effects of Al(III) Phthalocyanine Chloride Disulfonic Acid (AlPcS2a) – in vitro studies on AY-27 and T-24 cells
Rutledal, Carina Franing (Master thesis, 2021)Fotodynamisk terapi (PDT) er en behandlingsmetode som benytter et fotosensibiliserende stoff (PS) som induserer celledød ved aktivering av lys. Fotokjemisk internalisering (PCI) er en ny teknologi som bygger videre på de ... -
Photosensitizing Effects of Novel Glycosylated Chlorin Complexes on the AY-27 Cancer Cell Model
Vindstad, Benedikte Emilie (Master thesis, 2020)Målet for dette prosjektet var å finne potensialet til KA20-familien av glykosylerte kloriner som fotosensibiliserende forbindelser i fotodynamisk terapi (PDT) av kreftsykdom. Kreft er en av verdens ledende dødsårsaker. ... -
Screening of a New Class of Fluorescent Probes for Diagnosis of Amyloid Deposits
Konsmo, Audun (Master thesis, 2018)The purpose of this project has been to determine photo-physical properties of new and untested fluorescent probes. The probes have a 2,1,3-benzothiadiazole (BTD) ring structure and are derivatives of the previously explored ... -
Solid solubility of rare earth elements (Nd, Eu, Tb) in In2−xSnxO3 – effect on electrical conductivity and optical properties
Sunde, Tor Olav Løveng; Lindgren, Mikael; Mason, TO; Einarsrud, Mari-Ann; Grande, Tor (Journal article; Peer reviewed, 2014-05-07)Wide band-gap semiconductors doped with luminescent rare earth elements (REEs) have attracted recent interest due to their unique optical properties. Here we report on the synthesis of the transparent conducting oxides ... -
Some Fluorescent Ligands for Studying Amyloid Uptake in Human Cell Models
Sundnes, Marikken Lærum (Master thesis, 2023)Det er økende forekomst av patologier kjennetegnet av amyloidose, der proteiner feilfoldes til giftige, uløselige aggregater kjent som amyloider. Et slikt misfoldende protein er transportproteinet Transthyretin (TTR), som ... -
Spectral correlation analysis of Amyloid beta plaque inhomogeneity from double staining experiments
Ellingsen, Pål Gunnar; Nyström, Sofie; Reitan, Nina Kristine; Lindgren, Mikael (Journal article; Peer reviewed, 2013)A spectral correlation algorithm for the analysis of hyperspectral fluorescence images is proposed by Ellingsen et al. [J. Biomed. Opt. 18, 020501 (2013)]. Here, it is applied to the analysis of double-stained Aβ amyloid ... -
Spectroscopic characterization and performance of novel triplet state enhanced molecules for optical power limiting
Hopen, Didrik Kvanvik (Master thesis, 2018)Finding molecules with good optical power limiting (OPL) performance is of greatimportance for the use in OPL filters made for protecting against harmful lasers used inan expanding set of technologies. In this ... -
Spectroscopic Diversity of Fluorescent Amyloid Ligand Interactions with Native Transthyretin
Leira, Petter (Master thesis, 2020)Proteinet Transthyretin (TTR) er et transportprotein knyttet til en rekke sykdommer kalt amyloidose. Amyloidose er karakterisert ved at avleiringer av proteiner danner skadelige amyloidfibriller som er svært stabile og ... -
Synthesis and characterization of novel fluoro-glycosylated porphyrins that can be utilized as theranostic agents
Arja, Katriann; Elgland, Mathias; Appelquist, Hanna; Konradsson, Peter; Lindgren, Mikael; Nilsson, K. Peter R. (Journal article; Peer reviewed, 2018)Small molecules with modalities for a variety of imaging techniques as well as therapeutic activity are essential, as such molecules render opportunities to simultaneously conduct diagnosis and targeted therapy, so called ... -
Synthesis and in vitro evaluation of a novel thienopyrimidine with phototoxicity towards rat glioma F98 cells
Gederaas, Odrun Arna; Sørensen, Andreas S.; Lindgren, Mikael; Melø, Thor Bernt; Altin, Dag; Flatby, Ellen M. Samdahl; Høgset, Anders; Hoff, Bård Helge (Peer reviewed; Journal article, 2022)Glioblastoma multiforme is one of the most aggressive cancer forms in humans, and has low recovery rates after surgery, ionizing radiation and chemotherapy. Therefore, there is a high interest in the development of new ... -
Tau Protein Binding Modes in Alzheimer’s Disease for Cationic Luminescent Ligands
Todarwal, Yogesh; Gustafsson, Camilla; Thi Minh, Nghia Nguyen; Ertzgaard, Ingrid; Klingstedt, Thérese; Ghetti, Bernardino; Vidal, Ruben; König, Carolin; Lindgren, Mikael; Nilsson, K. Peter R.; Linares, Mathieu; Norman, Patrick (Journal article; Peer reviewed, 2021)The bi-thiophene-vinylene-benzothiazole (bTVBT4) ligand developed for Alzheimer’s disease (AD)-specific detection of amyloid tau has been studied by a combination of several theoretical methods and experimental spectroscopies. ... -
trans-Stilbenoids with Extended Fluorescence Lifetimes for the Characterization of Amyloid Fibrils
Zhang, Jun; Sandberg, Alexander; Wu, Xiongyu; Nyström, Sofie; Lindgren, Mikael; Konradsson, Peter; Hammarström, Per (Journal article; Peer reviewed, 2017)It was previously reported that two naphthyl-based trans-stilbene probes, (E)-4-(2-(naphthalen-1-yl)vinyl)benzene-1,2-diol (1) and (E)-4-(2-(naphthalen-2-yl)vinyl)benzene-1,2-diol (3), can bind to both native transthyretin ... -
Tyrosine Side-Chain Functionalities at Distinct Positions Determine the Chirooptical Properties and Supramolecular Structures of Pentameric Oligothiophenes
Bäck, Marcus; Selegård, Robert; Todarwal, Yogesh; Nyström, Sofie; Norman, Patrick; Linares, Mathieu; Hammarström, Per; Lindgren, Mikael; Nilsson, K. Peter R. (Peer reviewed; Journal article, 2020)Control over the photophysical properties and molecular organization of π-conjugated oligothiophenes is essential to their use in organic electronics. Herein we synthesized and characterized a variety of anionic pentameric ...