• Body mass index and incidence of lung cancer in the HUNT study: using observational and Mendelian randomization approaches 

      Jiang, Lin; Sun, Yi-Qian; Brumpton, Ben Michael; Langhammer, Arnulf; Chen, Yue; Mai, Xiao-Mei (Peer reviewed; Journal article, 2022)
      Background Traditional observational studies have shown an inverse association between body mass index (BMI) and lung cancer risk. Mendelian randomization (MR) analysis using genetic variants as instruments for BMI may ...
    • Bruk av skjermbaserte medier blant eldre under covid-19-pandemien : en HUNT studie 

      Eriksen, Siren; Rokstad, Anne Marie Mork; Selbæk, Geir; Björklöf, Guro Hanevold; Tveito, Marit; Bergh, Sverre; Langhammer, Arnulf; Næss, Marit; Ibsen, Tanja Louise (Peer reviewed; Journal article, 2022)
      Bakgrunn: Eldre er spesielt sårbare for alvorlig sykdom og død ved covid-19 og har blitt oppfordret til selvisolering under koronapandemien. Skjermbaserte medier og telefon har blitt fremhevet som viktige hjelpemidler for ...
    • Cancer patients' participation in population-based health surveys: Findings from the HUNT studies Cancer 

      Fosså, Sophie Dorothea; Dahl, Alv A; Langhammer, Arnulf; Weedon-Fekjær, Harald (Peer reviewed; Journal article, 2015)
      Background:The magnitude of participation bias due to non‑participation should be considered for cancer patients invited to population‑based surveys. We studied participation rates among persons with and without cancer in ...
    • Changes in lung function in European adults born between 1884 and 1996 and implications for the diagnosis of lung disease: a cross-sectional analysis of ten population-based studies 

      Allinson, James P; Afzal, Shoaib; Çolak, Yunus; Jarvis, Debbie; Backman, Helena; van den Berge, Maarten; Boezen, H Marike; Breyer, Marie-Kathrin; Breyer-Kohansal, Robab; Brusselle, Guy; Burghuber, Otto C; Faner, Rosa; Hartl, Sylvia; Lahousse, Lies; Langhammer, Arnulf; Lundbäck, Bo; Nwaru, Bright I; Rönmark, Eva; Vikjord, Sigrid Anna Aalberg; Vonk, Judith M; Wijnant, Sara R A; Lange, Peter; Nordestgaard, Børge G; Olvera, Nuria; Agusti, Alvar; Donaldson, Gavin C; Wedzicha, Jadwiga A; Vestbo, Jørgen; Vanfleteren, Lowie E G W (Peer reviewed; Journal article, 2022)
      Background During the past century, socioeconomic and scientific advances have resulted in changes in the health and physique of European populations. Accompanying improvements in lung function, if unrecognised, could ...
    • Circulating concentrations of biomarkers and metabolites related to Vitamin status, one-carbon and the kynurenine pathways in US, Nordic, Asian, and Australian populations 

      Midttun, Øivind; Theofylaktopoulou, Despoina; Mccann, Adrian; Fanidi, Anouar; Muller, David C.; Meyer, Klaus; Ulvik, Arve; Zheng, Wei; Shu, Xiao-Ou; Xiang, Yong-Bing; Prentice, Ross; Thomson, Cynthia A.; Pettinger, Mary; Giles, Graham G.; Hodge, Allison; Cai, Qiuyin; Blot, William J.; Wu, Jie; Johansson, Mikael; Hultdin, Johan; Grankvist, Kjell; Stevens, Victoria L.; McCullough, Marjorie L.; Weinstein, Stephanie J.; Albanes, Demetrius; Langhammer, Arnulf; Hveem, Kristian; Næss, Marit; Sesso, Howard D.; Gaziano, J. Michael; Buring, Julie E.; Lee, I-Min; Severi, Gianluca; Zhang, Xuehong; Han, Jiali; Stampfer, Meir J.; Smith-Warner, Stephanie A.; Zeleniuch-Jacquotte, Anne; Le Marchand, Loic; Yuan, Jian-Min; Butler, Lesley M.; Koh, Woon-Puay; Wang, Renwei; Gao, Yu-Tang; Ericson, Ulrika; Sonestedt, Emily; Ziegler, Regina G.; Freedman, Neal D.; Visvanathan, Kala; Jones, Miranda R.; Relton, Caroline; Brennan, Paul; Johansson, Mattias; Ueland, Per Magne (Journal article; Peer reviewed, 2017)
      Background: Circulating concentrations of biomarkers that are related to vitamin status vary by factors such as diet, fortification, and supplement use. Published biomarker concentrations have also been influenced by the ...
    • Circulating cotinine concentrations and lung cancer risk in the Lung Cancer Cohort Consortium (LC3) 

      Larose, Tricia L; Guida, Florence; Anouar, Fanidi; Langhammer, Arnulf; Hveem, Kristian; Stevens, Victoria L.; Jacobs, Eric J.; Smith-Warner, Stephanie A.; Giovannucci, Edward; Albanes, Demetrius; Weinstein, Stephanie J.; Freedman, Neal D.; Prentice, Ross; Pettinger, Mary; Thomson, Cynthia A.; Cai, Qiuyin; Wu, Jie; Blot, William J; Arslan, Alan A.; Zeleniuch-Jacquotte, Anne; Le Marchand, Loic; Wilkens, Lynne R.; Haiman, Christopher A.; Zhang, Xuehong; Stampfer, Meir J; Hodge, Allison M.; Giles, Graham G.; Severi, Gianluca; Johansson, Mikael; Grankvist, Kjell; Wang, Renwei; Yuan, Jian-Min; Gao, Yu-Tang; Koh, Woon-Puay; Shu, Xiao-Ou; Zheng, Wei; Xiang, Yong-Bing; Li, Honglan; Lan, Qing; Visvanathan, Kala; Hoffman Bolton, Judith; Ueland, Per Magne; Midttun, Øivind; Caporaso, Neil; Purdue, Mark; Sesso, Howard D.; Buring, Julie E.; Lee, I-Min; Gaziano, J. Michael; Manjer, Jonas; Brunnström, Hans; Brennan, Paul; Johansson, Mattias (Journal article; Peer reviewed, 2018)
      Background Self-reported smoking is the principal measure used to assess lung cancer risk in epidemiological studies. We evaluated if circulating cotinine—a nicotine metabolite and biomarker of recent tobacco exposure—provides ...
    • Circulating high sensitivity C reactive protein concentrations and risk of lung cancer: Nested case-control study within Lung Cancer Cohort Consortium 

      Muller, David C.; Larose, Tricia L; Hodge, Allison; Guida, Florence; Langhammer, Arnulf; Grankvist, Kjell; Meyer, Klaus; Cai, Qiuyin; Arslan, Alan A.; Zeleniuch-Jacquotte, Anne; Albanes, Demetrius; Giles, Graham G.; Sesso, Howard D.; Lee, I-Min; Gaziano, J. Michael; Yuan, Jian-Min; Hoffman Bolton, Judith; Buring, Julie E.; Visvanathan, Kala; Le Marchand, Loic; Purdue, Mark P.; Caporaso, Neil E.; Midttun, Øivind; Ueland, Per Magne; Prentice, Ross L.; Weinstein, Stephanie J.; Stevens, Victoria L.; Zheng, Wei; Blot, William J.; Shu, Xiao-Ou; Zhang, Xuehong; Xiang, Yong-Bing; Koh, Woon-Puay; Hveem, Kristian; Thomson, Cynthia A.; Pettinger, Mary; Engström, Gunnar; Brunnström, Hans; Milne, Roger L.; Stampfer, Meir J.; Han, Jiali; Johansson, Mikael; Brennan, Paul; Severi, Gianluca; Johansson, Mattias (Journal article; Peer reviewed, 2019)
      Objectives: Inflammation may play an important role in lung cancer pathogenesis. Previous studies have suggested an association between C-reactive protein (CRP) as a marker of inflammation, and risk of lung cancer, but ...
    • Circulating markers of cellular immune activation in pre-diagnostic blood sample and lung cancer risk in the Lung Cancer Cohort Consortium (LC3) 

      Huang, Joyce Yongxu; Larose, Tricia L; Luu, Hung N; Wang, Renwei; Fanidi, Anouar; Alcala, Karine; Stevens, Victoria L.; Weinstein, Stephanie J.; Albanes, Demetrius; Caporaso, Neil E.; Purdue, Mark P.; Ziegler, Regina G.; Freedman, Neal D.; Lan, Qing; Prentice, Ross L.; Pettinger, Mary; Thomson, Cynthia A.; Cai, Qiuyin; Wu, Jie; Blot, William J.; Shu, Xiao-Ou; Zheng, Wei; Arslan, Alan A.; Zeleniuch-Jacquotte, Anne; Le Marchand, Loïc; Wilkens, Lynn R; Haiman, Christopher A.; Zhang, Xuehong; Stampfer, Meir J.; Han, Jiali; Giles, Graham G.; Hodge, Allison M.; Severi, Gianluca; Johansson, Mikael; Grankvist, Kjell; Langhammer, Arnulf; Hveem, Kristian; Xiang, Yong-Bing; Li, Hong-Lan; Gao, Yu-Tang; Visvanathan, Kala; Ueland, Per Magne; Midttun, Øivind; Ulvik, Arve; Buring, Julie E.; Lee, I-Min; Sesso, Howard D.; Gaziano, J. Michael; Manjer, Jonas; Relton, Caroline; Koh, Woon-Puay; Brennan, Paul; Johansson, Mattias; Yuan, Jian-Min (Journal article; Peer reviewed, 2019)
      Cell‐mediated immune suppression may play an important role in lung carcinogenesis. We investigated the associations for circulating levels of tryptophan, kynurenine, kynurenine:tryptophan ratio (KTR), quinolinic acid (QA) ...
    • Cod liver oil intake and incidence of asthma in Norwegian adults-the HUNT study 

      Mai, Xiao-Mei; Langhammer, Arnulf; Chen, Yue; Camargo, Carlos Arthuro (Journal article; Peer reviewed, 2013)
      Background Cod liver oil is an important source of vitamin D, but also contains other fat-soluble components such as vitamin A. Before 1999, the cod liver oil formula in Norway contained a high concentration of vitamin A ...
    • Cohort Profile Update: The HUNT Study, Norway 

      Åsvold, Bjørn Olav; Langhammer, Arnulf; Rehn, Tommy Aune; Kjelvik, Grete; Grøntvedt, Trond Viggo; Sørgjerd, Elin Pettersen; Fenstad, Jørn; Heggland, Jon; Holmen, Oddgeir; Stuifbergen, Maria C; Vikjord, Sigrid Anna Aalberg; Brumpton, Ben Michael; Skjellegrind, Håvard; Thingstad, Pernille; Sund, Erik; Selbæk, Geir; Mork, Paul Jarle; Rangul, Vegar; Hveem, Kristian; Næss, Marit; Krokstad, Steinar (Peer reviewed; Journal article, 2022)
    • Cohort Profile Update: The Young-HUNT Study, Norway 

      Rangul, Vegar; Holmen, Turid Lingaas; Langhammer, Arnulf; Ingul, Jo Magne; Pape, Kristine; Fenstad, Jørn Søberg; Kvaløy, Kirsti (Peer reviewed; Journal article, 2024)
      The Young-HUNT Study is the adolescent part of the Trøndelag Health Study (The HUNT Study), a population-based health study inviting all inhabitants, aged 13 years and above, of primarily the northern part of Trøndelag ...
    • The combined effect of exposures to vapours, gases, dusts, fumes and tobacco smoke on current asthma 

      Hisinger-Mölkänen, Hanna; Kankaanranta, Hannu; Haahtela, Tari; Sovijärvi, Anssi; Tuomisto, Leena; Andersén, Heidi; Lindqvist, Ari; Backman, Helena; Langhammer, Arnulf; Rönmark, Eva; Ilmarinen, Pinja; Pallasaho, Paula; Piirilä, Päivi (Peer reviewed; Journal article, 2022)
      Smoking, exposure to environmental tobacco smoke (ETS) and occupational exposure to vapours, gases, dusts or fumes (VGDF) increase asthma symptoms. The impact of combined exposure is less well established. We aimed to ...
    • Comparison of pre‐ and post‐bronchodilator lung function as predictors of mortality: The HUNT Study 

      Bhatta, Laxmi; Leivseth, Linda; Carslake, David; Langhammer, Arnulf; Mai, Xiao-Mei; Chen, Yue; Henriksen, Anne Hildur; Brumpton, Ben Michael (Peer reviewed; Journal article, 2019)
      Background and objective Post‐bronchodilator (BD) lung function is recommended for the diagnosis of chronic obstructive pulmonary disease (COPD). However, often only pre‐BD lung function is used in clinical practice or ...
    • Cross-Sectional and Prospective Cohort Study of Serum 25-Hydroxyvitamin D Level and Obesity in Adults 

      Mai, Xiao-Mei; Chen, Yue; Camargo, Carlos Arthuro; Langhammer, Arnulf (Journal article; Peer reviewed, 2012)
      Experimental studies suggest that vitamin D modulates the activity of adipocytes. The authors examined baseline serum 25-hydroxyvitamin D (25(OH)D) level in relation to prevalent and cumulative incident obesity in Norway. ...
    • A cross-sectional study of inflammatory markers as determinants of circulating kynurenines in the Lung Cancer Cohort Consortium 

      Midttun, Øivind; Ulvik, Arve; Meyer, Klaus; Zahed, Hana; Giles, Graham G.; Manjer, Jonas; Sandsveden, Malte; Langhammer, Arnulf; Sørgjerd, Elin Pettersen; Behndig, Annelie F.; Johansson, Mikael; Freedman, Neal D.; Huang, Wen-Yi; Chen, Chu; Prentice, Ross; Stevens, Victoria L.; Wang, Ying; Le Marchand, Loïc; Weinstein, Stephanie J.; Cai, Qiuyin; Arslan, Alan A.; Chen, Yu; Shu, Xiao-Ou; Zheng, Wei; Yuan, Jian-Min; Koh, Woon-Puay; Visvanathan, Kala; Sesso, Howard D.; Zhang, Xuehong; Gaziano, J. Michael; Fanidi, Anouar; Robbins, Hilary A.; Brennan, Paul; Johansson, Mattias; Ueland, Per Magne (Peer reviewed; Journal article, 2023)
      Circulating concentrations of metabolites (collectively called kynurenines) in the kynurenine pathway of tryptophan metabolism increase during inflammation, particularly in response to interferon-gamma (IFN-γ). Neopterin ...
    • Diagnostic labelling and implications for health, a population-based study 

      Jørgensen, Pål (Doctoral theses at NTNU;2018:8, Doctoral thesis, 2018)
      NORSK POPULÆRVITENSKAPELIG SAMMENDRAG Helsemessige konsekvenser av kjennskap til egen diagnose – en populasjonsbasert studie Epidemien av «ikke-smittsomme sykdommer» og livsstilssykdommer blir gjerne sett på som den ...
    • Does treatment with bisphosphonates protect against fractures in real life? The HUNT study, Norway 

      Hoff, Mari; Skovlund, Eva; Meyer, Haakon E; Langhammer, Arnulf; Søgaard, Anne-Johanne; Syversen, Unni; Holvik, Kristin; Abrahamsen, Bo; Schei, Berit (Peer reviewed; Journal article, 2021)
      Summary Bisphosphonates reduce fractures in randomized controlled trials (RCT); however, there is less information from real life. In our population including 14,990 women and 13,239 men, use of bisphosphonates reduced ...
    • Effekt av livsstilsfaktorer som røyking, kaffe- og tekonsum på beinmineraltetthet (BMD) i en prospektiv studie 

      Oskal, Kristin Bekkelund (Master thesis, 2013)
      Målsetting: Å beskrive effekten av røyking og konsum av koffeinholdige drikker som kaffe og te på beinmineraltetthet (BMD) i hofter og korsrygg hos kvinner  og menn 50-79 år. Materiale og metode: ...
    • Epidemiology of 40 blood biomarkers of one-carbon metabolism, vitamin status, inflammation, and renal and endothelial function among cancer-free older adults 

      Zahed, Hana; Johansson, Mattias; Ueland, Per Magne; Midttun, Øivind; Milne, Roger L.; Giles, Graham G.; Manjer, Jonas; Sandsveden, Malte; Langhammer, Arnulf; Sørgjerd, Elin Pettersen; Grankvist, Kjell; Johansson, Mikael; Freedman, Neal D.; Huang, Wen-Yi; Chen, Chu; Prentice, Ross; Stevens, Victoria L.; Wang, Ying; Le Marchand, Loic; Wilkens, Lynne R.; Weinstein, Stephanie J.; Albanes, Demetrius; Cai, Qiuyin; Blot, William J.; Arslan, Alan A.; Zeleniuch-Jacquotte, Anne; Shu, Xiao-Ou; Zheng, Wei; Yuan, Jian-Min; Koh, Woon-Puay; Visvanathan, Kala; Sesso, Howard D.; Zhang, Xuehong; Gaziano, J. Michael; Fanidi, Anouar; Muller, David; Brennan, Paul; Guida, Florence; Robbins, Hilary A. (Peer reviewed; Journal article, 2021)
      Imbalances of blood biomarkers are associated with disease, and biomarkers may also vary non-pathologically across population groups. We described variation in concentrations of biomarkers of one-carbon metabolism, vitamin ...