• Prostate-specific membrane antigen PET/MRI for prostate cancer: technical advancements, image interpretation, and clinical management 

      Abrahamsen, Bendik Skarre (Doctoral theses at NTNU;2024:97, Doctoral thesis, 2024)
      Prostate cancer is the most commonly diagnosed cancer in men. In the Norwegian population, it is expected that as many as one in nine men will develop prostate cancer by the age of 75. Through early detection and effective ...
    • Pseudo-T2 mapping for normalization of T2-weighted prostate MRI 

      Sørland, Kaia Ingerdatter; Sunoqrot, Mohammed R. S.; Sandsmark, Elise; Langørgen, Sverre; Bertilsson, Helena; Trimble, Christopher George; Lin, Gigin; Selnæs, Kirsten Margrete; Goa, Pål Erik; Bathen, Tone Frost; Elschot, Mattijs (Peer reviewed; Journal article, 2022)
      Objective Signal intensity normalization is necessary to reduce heterogeneity in T2-weighted (T2W) magnetic resonance imaging (MRI) for quantitative analysis of multicenter data. AutoRef is an automated dual-reference ...
    • A Quality Control System for Automated Prostate Segmentation on T2-Weighted MRI 

      Sunoqrot, Mohammed R. S.; Selnæs, Kirsten Margrete; Sandsmark, Elise; Nketiah, Gabriel Addio; Zavala-Romero, Olmo; Stoyanova, Radka; Bathen, Tone Frost; Elschot, Mattijs (Journal article; Peer reviewed, 2020)
      Computer-aided detection and diagnosis (CAD) systems have the potential to improve robustness and efficiency compared to traditional radiological reading of magnetic resonance imaging (MRI). Fully automated segmentation ...
    • Quantitative prostate cancer MRI: status, challenges and opportunities 

      Sørland, Kaia Ingerdatter (Doctoral theses at NTNU;2024:77, Doctoral thesis, 2024)
      Prostate cancer was in 2020 the most frequently diagnosed cancer in men in over half of the world’s countries, and the leading cause of cancer death among men in 48 countries. Medical imaging is one of the main pillars of ...
    • Reducing prostate biopsies and magnetic resonance imaging with prostate cancer risk stratification 

      Davik, Petter; Remmers, Sebastiaan; Elschot, Mattijs; Roobol, Monique J; Bathen, Tone Frost; Bertilsson, Helena (Journal article; Peer reviewed, 2022)
    • Relative Enhanced Diffusivity in Prostate Cancer: Protocol Optimization and Diagnostic Potential 

      Billdal, Daniel Chen; While, Peter Thomas; Selnæs, Kirsten Margrete; Sunoqrot, Mohammed; Langørgen, Sverre; Bertilsson, Helena; Bathen, Tone Frost; Elschot, Mattijs (Journal article; Peer reviewed, 2019)
      Background Relative enhanced diffusivity (RED) is a potential biomarker for indirectly measuring perfusion in tissue using diffusion‐weighted magnetic resonance imaging (MRI) with 3 b values. Purpose To optimize the RED ...
    • The Reproducibility of Deep Learning-Based Segmentation of the Prostate Gland and Zones on T2-Weighted MR Images 

      Sunoqrot, Mohammed R. S.; Selnæs, Kirsten Margrete; Sandsmark, Elise; Langørgen, Sverre; Bertilsson, Helena; Bathen, Tone Frost; Elschot, Mattijs (Peer reviewed; Journal article, 2021)
      Volume of interest segmentation is an essential step in computer-aided detection and diagnosis (CAD) systems. Deep learning (DL)-based methods provide good performance for prostate segmentation, but little is known about ...
    • Simultaneous 18F-fluciclovine Positron Emission Tomography and Magnetic Resonance Spectroscopic Imaging of Prostate Cancer 

      Esmaeili, Morteza; Tayari, Nassim; Scheenen, Tom WJ; Elschot, Mattijs; Sandsmark, Elise; Bertilsson, Helena; Heerschap, Arend; Selnæs, Kirsten Margrete; Bathen, Tone Frost (Journal article; Peer reviewed, 2018)
      Purpose: To investigate the associations of metabolite levels derived from magnetic resonance spectroscopic imaging (MRSI) and 18F-fluciclovine positron emission tomography (PET) with prostate tissue characteristics. Methods: ...
    • The Effect of Including Bone in DIXON-based Attenuation Correction for 18F-fluciclovine PET/MRI of Prostate Cancer 

      Elschot, Mattijs; Selnæs, Kirsten Margrete; Johansen, Håkon; Krüger-Stokke, Brage; Bertilsson, Helena; Bathen, Tone Frost (Journal article; Peer reviewed, 2018)
      The objective of this study was to evaluate the effect of including bone in DIXON-based attenuation correction for 18F-fluciclovine Positron Emission Tomography (PET) / Magnetic Resonance Imaging (MRI) of primary and ...
    • TLR3 expression by maternal and fetal cells at the maternal-fetal interface in normal and preeclamptic pregnancies 

      Gierman, Lobke; Silva, Gabriela; Pervaiz, Zahra; Rakner, Johanne Johnsen; Mundal, Siv Boon; Thaning, Astrid J.; Nervik, Ingunn; Elschot, Mattijs; Mathew, Seema; Thomsen, Liv Cecilie Vestrheim; Bjørge, Line; Iversen, Ann-Charlotte (Peer reviewed; Journal article, 2020)
      Inflammation and oxidative stress at the maternal‐fetal interface characterize the placental dysfunction that underlies the pregnancy disorder preeclampsia. Specialized fetal trophoblasts directly interact with leukocytes ...
    • Tumor Targeting by αvβ3-Integrin-Specific Lipid Nanoparticles Occurs via Phagocyte Hitchhiking 

      Sofias, Alexandros Marios; Toner, Yohana C.; Meerwaldt, Anu E.; van Leent, Mandy M. T.; Soultanidis, Georgios; Elschot, Mattijs; Gonai, Haruki; Grendstad, Kristin; Flobak, Åsmund; Neckmann, Ulrike; Wolowczyk, Camilla; Fisher, Elizabeth L.; Reiner, Thomas; Davies, Catharina de Lange; Bjørkøy, Geir; Teunissen, Abraham J. P.; Ochando, Jordi; Pérez-Medina, Carlos; Mulder, Willem J. M.; Hak, Sjoerd (Journal article; Peer reviewed, 2020)
      Although the first nanomedicine was clinically approved more than two decades ago, nanoparticles’ (NP) in vivo behavior is complex and the immune system’s role in their application remains elusive. At present, only ...
    • Utility of T2-weighted MRI texture analysis in assessment of peripheral zone prostate cancer aggressiveness: a single-arm, multicenter study 

      Nketiah, Gabriel Addio; Elschot, Mattijs; Scheenen, Tom W.J.; Maas, Marnix C.; Bathen, Tone Frost; Selnæs, Kirsten Margrete (Peer reviewed; Journal article, 2021)
      T2-weighted (T2W) MRI provides high spatial resolution and tissue-specific contrast, but it is predominantly used for qualitative evaluation of prostate anatomy and anomalies. This retrospective multicenter study evaluated ...
    • Vision transformers as a support for prostate cancer detection 

      Zelenčík, Michal (Master thesis, 2023)
      Dette arbeidet undersøker muligheten for å bruke Vision Transformers for å detektere prostatakreft og segmentere kreft i MR bilder. Vi har laget en tilpasset arkitektur som ga bedre resultater enn toppmoderne modeller ...