Blar i NTNU Open på forfatter "Carlsen, Sven Magnus"
-
Incidence and Case Fatality of Aneurysmal Subarachnoid Hemorrhage Admitted to Hospital Between 2008 and 2014 in Norway
Øie, Lise Rystad; Solheim, Ole; Majewska, Paulina Luiza; Nordseth, Trond; Müller, Tomm Brostrup; Carlsen, Sven Magnus; Jensberg, Heidi; Salvesen, Øyvind; Gulati, Sasha (Peer reviewed; Journal article, 2020)Background To provide age- and sex-specific incidence and case fatality rates for non-traumatic aneurysmal subarachnoid hemorrhage (aSAH) in Norway. We also studied time trends in incidence and case fatality, as well as ... -
Intraperitoneal and subcutaneous glucagon delivery in anaesthetized pigs: effects on circulating glucagon and glucose levels
Åm, Marte Kierulf; Dirnena-Fusini, Ilze; Fougner, Anders Lyngvi; Carlsen, Sven Magnus; Christiansen, Sverre (Journal article; Peer reviewed, 2020)Glucagon is a pancreatic hormone and increases the blood glucose levels. It may be incorporated in a dual hormone artificial pancreas, a device to automatically and continuously control blood glucose levels of individuals ... -
The intraperitoneal artificial pancreas: glucose sensing and glucagon delivery
Åm, Marte Kierulf (Doctoral theses at NTNU;2020:267, Doctoral thesis, 2020)Norsk sammendrag Diabetes er en gruppe sykdommer som globalt rammer millioner av mennesker. Denne avhandlingen fokuserer på diabetes mellitus type 1 som kjennetegnes av ingen, eller veldig liten, produksjon av insulin. ... -
Intraperitoneal insulin administration - superior choice for an artificial pancreas?
Dirnena-Fusini, Ilze (Doctoral theses at NTNU;2021:334, Doctoral thesis, 2021)The main focus of this thesis is to explore the intraperitoneal (IP) cavity as the location for insulin administration. We hypothesized that IP insulin administration is more physiologic as it mimics endogenous insulin ... -
Intraperitoneal insulin administration in pigs: Effect on circulating insulin and glucose levels
Dirnena-Fusini, Ilze; Åm, Marte Kierulf; Fougner, Anders Lyngvi; Carlsen, Sven Magnus; Christiansen, Sverre Christian (Peer reviewed; Journal article, 2021)Introduction The effect of intraperitoneal insulin infusion has limited evidence in the literature. Therefore, the aim of the study was to investigate the pharmacokinetics and pharmacodynamics of different intraperitoneal ... -
Intraperitoneal, subcutaneous and intravenous glucagon delivery and subsequent glucose response in rats: A randomized controlled crossover trial
Dirnena-Fusini, Ilze; Åm, Marte Kierulf; Fougner, Anders Lyngvi; Carlsen, Sven Magnus; Christiansen, Sverre (Journal article; Peer reviewed, 2018)Objective Hypoglycemia is a frequent and potentially dangerous event among patients with diabetes mellitus type 1. Subcutaneous glucagon is an emergency treatment to counteract severe hypoglycemia. The effect of intraperitoneal ... -
Maternal PCOS status and metformin in pregnancy: Steroid hormones in 5–10 years old children from the PregMet randomized controlled study
Hanem, Liv Guro Engen; Salvesen, Øyvind; Madsen, Andre; Sagen, Jørn Vegard; Mellgren, Gunnar; Juliusson, Petur Benedikt; Carlsen, Sven Magnus; Vanky, Eszter; Ødegård, Rønnaug (Peer reviewed; Journal article, 2021)Objective Polycystic ovary syndrome (PCOS) is a common endocrine disorder, with potential effects on offspring both genetically and through altered intrauterine environment. Metformin, which ameliorate hormonal disturbances ... -
Metformin in Pregnancy Study (MiPS): protocol for a systematic review with individual patient data meta-analysis
Mousa, Aya; Løvvik, Tone Shetelig; Ijas, Hilkka; Carlsen, Sven Magnus; Morin-Papunen, Laure; Tertti, Kristiina; Rönnema, Tapani; Syngelaki, Argyro; Nicolaides, Kypros; Shehata, Hassan; Burden, Chirsty; Rowan, Janet; Norman, Jane E.; Dodd, Jodie M.; Hague, William; Vanky, Eszter; Teede, Helena J. (Peer reviewed; Journal article, 2020)Introduction: Gestational diabetes mellitus (GDM) is a common disorder of pregnancy and contributes to adverse pregnancy outcomes. Metformin is often used for the prevention and management of GDM; however, its use in ... -
No impact of gestational diabetes mellitus on pregnancy complications in women with PCOS, regardless of GDM criteria used
Fougner, Stine Lyngvi; Vanky, Eszter; Løvvik, Tone Shetelig; Carlsen, Sven Magnus (Journal article; Peer reviewed, 2021)Polycystic ovary syndrome (PCOS) is characterized by the presence of insulin resistance, and women with PCOS have high prevalence of gestational diabetes (GDM). Both conditions have been associated with increased risk for ... -
Open discectomy vs microdiscectomy for lumbar disc herniation - a protocol for a pragmatic comparative effectiveness study
Sørlie, Andreas; Gulati, Sasha; Giannadakis, Charalampis; Carlsen, Sven Magnus; Salvesen, Øyvind; Nygaard, Øystein Petter; Solberg, Tore (Journal article; Peer reviewed, 2016)Introduction: Since the introduction of lumbar microdiscectomy in the 1970’s, many studies have attempted to compare the effectiveness of this method with that of standard open discectomy with conflicting results. This ... -
Pharmacokinetics of Intraperitoneally Delivered Glucagon in Pigs: A Hypothesis of First Pass Metabolism
Teigen, Ingrid Anna; Åm, Marte Kierulf; Carlsen, Sven Magnus; Christiansen, Sverre Christian (Peer reviewed; Journal article, 2021)Background and Objective Artificial pancreases administering low-dose glucagon in addition to insulin have the scope to improve glucose control in patients with diabetes mellitus type 1. If such a device were to deliver ... -
Physiological effects of intraperitoneal versus subcutaneous insulin infusion in patients with diabetes mellitus type 1: A systematic review and meta-analysis
Dirnena-Fusini, Ilze; Åm, Marte Kierulf; Fougner, Anders Lyngvi; Carlsen, Sven Magnus; Christiansen, Sverre Christian (Peer reviewed; Journal article, 2021)The intraperitoneal route of administration accounts for less than 1% of insulin treatment regimes in patients with diabetes mellitus type 1 (DM1). Despite being used for decades, a systematic review of various physiological ... -
Risk Analysis for the Design of a Safe Artificial Pancreas Control System
Kölle, Konstanze; Fougner, Anders Lyngvi; Lundteigen, Mary Ann; Carlsen, Sven Magnus; Ellingsen, Reinold; Stavdahl, Øyvind (Journal article; Peer reviewed, 2018)Closed-loop glucose control has the potential to improve the glycemic control in patients with diabetes mellitus type 1. Such an artificial pancreas (AP) should keep the user safe despite all disturbances and faults. The ... -
Risk of intracranial hemorrhage (RICH) in users of oral antithrombotic drugs: Nationwide pharmacoepidemiological study
Gulati, Sasha; Solheim, Ole; Carlsen, Sven Magnus; Øie, Lise Rystad; Jensberg, Heidi; Gulati, Agnete Malm; Madsbu, Mattis Aleksander; Giannadakis, Charalampis; Jakola, Asgeir Store; Salvesen, Øyvind (Journal article; Peer reviewed, 2018)Background The risks of intracranial haemorrhage (ICH) associated with antithrombotic drugs outside clinical trials are gaining increased attention. The aim of this nationwide study was to investigate the risk of ICH ... -
Severe bradycardia and hypotension in anaesthetized pigs: Possible interaction between octreotide, xylazine, and atropine: A case series
Åm, Marte Kierulf; Teigen, Ingrid Anna; Carlsen, Sven Magnus; Christiansen, Sverre Christian (Peer reviewed; Journal article, 2023)Pigs are common animal models in diabetes research. Streptozotocin-induced destruction of pancreatic β-cells is used to induce diabetes in conscious pigs. However, in short-term non-recovery experiments, suppression of ... -
Surgery for herniated lumbar disc in private vs public hospitals: A pragmatic comparative effectiveness study
Madsbu, Mattis Aleksander; Salvesen, Øyvind; Carlsen, Sven Magnus; Westin, Steinar; Onarheim, Kristian; Nygaard, Øystein Petter; Solberg, Tore; Gulati, Sasha (Peer reviewed; Journal article, 2020)Background There is limited evidence on the comparative performance of private and public healthcare. Our aim was to compare outcomes following surgery for lumbar disc herniation (LDH) in private versus public hospitals. ... -
The Artificial Pancreas: A Dynamic Challenge
Stavdahl, Øyvind; Fougner, Anders Lyngvi; Kölle, Konstanze; Christiansen, Sverre Christian; Ellingsen, Reinold; Carlsen, Sven Magnus (Journal article; Peer reviewed, 2016)In patients with diabetes mellitus type 1, the pancreatic insulin production ceases, causing raise in blood glucose level (BGL) and potentially severe long-term complications. The “holy grail” of diabetes treatment is the ... -
THE ASSOCIATION BETWEEN CIRCULATING ANDROGEN HORMONES, MAXIMAL OXYGEN UPTAKE AND THE SYMPTOMS OF EATING DISORDERS AMONG FEMALE ATHLETES
Breivik, Torunn Haugen (Master thesis, 2013)Aim of the study: The aim was to analyse the possible associations between circulating androgen hormones, maximal oxygen uptake, and symptoms of eating disorders among female athletes. Method: In this cross-sectional study ... -
The Association between Circulating Androgen Levels, Body Composition, and Physical Performance in Female Soccer Players and Cross-Country Skiers
Bjørsnøs, Beate Vågen (Master thesis, 2012)Background: In recent research, links have been found between androgens and anabolic body composition. Some findings suggest that androgen hormones in female athletes are positively associated with both power and aerobic ... -
The Association between Physical Fitness, Body Composition and Bone Mineral Density among Female Athletes
Dregelid, Brit (Master thesis, 2013)Background: Research have suggested that endurance female athletes tend to have lower bone mineral density (BMD) than power and strength athletes, as a result of maintaining low body weight in addition to perform. This ...