Blar i NTNU Open på forfatter "Bye, Anja"
-
Genome-Wide Association Study Identifies New Genetic Determinants of Cardiorespiratory Fitness: The Trøndelag Health Study
Klevjer, Marie; Nordeidet, Ada Nilsen; Hansen, Ailin Falkmo; Madssen, Erik; Wisløff, Ulrik; Brumpton, Ben Michael; Bye, Anja (Peer reviewed; Journal article, 2022)Purpose Low cardiorespiratory fitness (CRF) is a major risk factor for cardiovascular disease (CVD) and a stronger predictor of CVD morbidity and mortality than established risk factors. The genetic component of CRF, ... -
Identification of new circulating biomarkers for risk prediction of lipid-rich coronary plaques and myocardial infarction
Sæther, Julie Caroline (Doctoral theses at NTNU;2023:433, Doctoral thesis, 2023)English summary Cardiovascular disease (CVD) is a major health burden and the leading cause of death worldwide, and myocardial infarction (MI) accounts for most CVD-related deaths. Risk prediction models are important ... -
Identification of novel genetic variants associated with cardiorespiratory fitness
Bye, Anja; Klevjer, Marie; Ryeng, Einar; Silva, Gustavo Jose Justo; Moreira, Jose Bianco Nascimento; Stensvold, Dorthe; Wisløff, Ulrik (Peer reviewed; Journal article, 2020)Introduction Low maximal oxygen uptake (VO2max) is a strong and independent risk factor for all-cause and cardiovascular disease (CVD) mortality. For other CVD risk factors, numerous genetic association studies have been ... -
Insight into the relationship between resting heart rate and atrial fibrillation: a Mendelian randomization study
Klevjer, Marie; Rasheed, Humaira; Romundstad, Pål Richard; Madssen, Erik; Brumpton, Ben Michael; Bye, Anja (Peer reviewed; Journal article, 2023)Aims A low resting heart rate (RHR) implies a more efficient heart function and a lower risk of cardiovascular disease. However, observational studies have reported a U-shaped association between RHR and atrial fibrillation ... -
Lipoprotein subfraction profiling in the search of new risk markers for myocardial infarction: The HUNT study
Sperstad, Sigri Bakken; Sæther, Julie Caroline; Klevjer, Marie; Giskeødegård, Guro F.; Bathen, Tone Frost; Røsbjørgen, Ragnhild; Dalen, Håvard; Bye, Anja (Peer reviewed; Journal article, 2023)Background Traditional biomarkers used to measure risk of myocardial infarction (MI) only explain a modest proportion of the incidence. Lipoprotein subfractions have the potential to improve risk prediction of MI. Aim We ... -
Physiological changes following 8 weeks of moderate exercise in older men.
Shahab, Ali Mohammed (Master thesis, 2013)Min masteroppgave går ut på å undersøke hvorvidt moderat trening påvirker DNA-metylering) i skjelettmuskulaturen hos eldre menn. Vi håper at dette kan gi oss mer kunnskap om hvordan trening påvirker muskulaturen til eldre, ... -
Powerful extreme phenotype sampling designs and score tests for genetic association studies
Bjørnland, Thea; Bye, Anja; Ryeng, Einar; Wisløff, Ulrik; Langaas, Mette (Journal article; Peer reviewed, 2018)We consider cross‐sectional genetic association studies (common and rare variants) where non‐genetic information is available or feasible to obtain for N individuals, but where it is infeasible to genotype all N individuals. ... -
Prognostic value of circulating microRNA-210 levels in patients with moderate to severe aortic stenosis
Røsjø, Helge; Dahl, Mai Britt; Bye, Anja; Andreassen, Johanna; Jørgensen, Marit; Wisløff, Ulrik; Christensen, Geir Arve; Edvardsen, Thor; Omland, Torbjørn (Journal article; Peer reviewed, 2014)Background: Circulating micro-RNAs have been proposed as a novel class of cardiovascular (CV) biomarkers, but whether they meet analytical requirements and provide additional information to establish risk indices have ... -
Risk Prediction of Cardiovascular Disease with Statistical Learning Methods
Wiig-Fisketjøn, Atle (Master thesis, 2021)I denne oppgaven ser vi på potensialet for bruk av metoder fra statistisk læring til å beregne risikoen for hjerte- og karsykdommer, ved å ta i bruk data fra Helseundersøkelsen i Trøndelag, HUNT. Hovedmålet med oppgaven ... -
Serum Levels of Choline-Containing Compounds Are Associated with Aerobic Fitness Level: The HUNT-Study
Bye, Anja; Vettukattil, Riyas M; Aspenes, Stian Thoresen; Giskeødegård, Guro F.; Gribbestad, Ingrid S; Wisløff, Ulrik; Bathen, Tone Frost (Journal article; Peer reviewed, 2012)Background: Cardiovascular disease (CVD) is a leading cause of death worldwide, and the number of people at risk is continuously growing. New methods for early risk prediction are therefore needed to actuate prevention ... -
Sex-specific and polygenic effects underlying resting heart rate and associated risk of cardiovascular disease
Nordeidet, Ada Nilsen; Klevjer, Marie; Øvretveit, Karsten; Madssen, Erik; Wisløff, Ulrik; Brumpton, Ben Michael; Bye, Anja (Journal article; Peer reviewed, 2024)Aims: Resting heart rate (RHR) is associated with cardiovascular disease (CVD) and mortality. This study aimed to identify genetic loci associated with RHR, develop a genome-wide polygenic risk score (PRS) for RHR, and ... -
Small LDL subfractions are associated with coronary atherosclerosis despite no differences in conventional lipids
Sæther, Julie Caroline; Klevjer, Marie; Giskeødegård, Guro F.; Bathen, Tone Frost; Gigante, Bruna; Gjære, Sigrid; Myhra, Marthe; Vesterbekkmo, Elisabeth Kleivhaug; Wiseth, Rune; Madssen, Erik; Bye, Anja (Journal article; Peer reviewed, 2023) -
Small LDL subfractions are associated with coronary atherosclerosis despite nodifferences in conventional lipids
Sæther, Julie Caroline; Klevjer, Marie; Giskeødegård, Guro F.; Bathen, Tone Frost; Gigante, Bruna; Gjære, Sigrid; Myhra, Marthe; Vesterbekkmo, Elisabeth Kleivhaug; Wiseth, Rune; Madssen, Erik; Bye, Anja (Peer reviewed; Journal article, 2022)Lipoprotein subfractions currently represent a new source of cardiovascular disease (CVD) risk markers that may provide more information than conventional lipid measures. We aimed to investigate whether lipoprotein ... -
Statistical Analysis of Interaction Effects Between Environmental and Genetic Factors
Erfjord, Lisa (Master thesis, 2021)I denne oppgaven analyseres interaksjonseffekten mellom genetiske faktorer og fysisk aktivitet når det kommer til risiko for å utvikle hjerte- og karsykdommer. Dette inkluderer å lage datasett, bli kjent med teorien fra ... -
The Effect of High Intensity Interval Training on Inflammatory Status and Cardiovascular Risk Factors in Females with Rheumatic Diseases
Sandstad, Janne (Master thesis, 2012)Abstract BACKGROUND: Arthritis and other rheumatic conditions are a growing health problem, in terms of prevalence, disability and cost. Rheumatism is classified as chronic, systemic, and autoimmune diseases. Major symptoms ... -
The Effect of High-intensity Interval Training on Maximal Aerobic Capacity, DNA Methylation and Gene Expression in Healthy Elderly Men
Andenæs, Kine (Master thesis, 2013)Physical activity is generally beneficial to maintain good health and prevent diseases. Development of some diseases may include epigenetic changes. Epigenetic changes involve alterations to the genome without changing the ... -
The impact of high intensity interval training on disease activity and patient disease perception in patients with psoriatic arthritis: a randomized controlled trial
Thomsen, Ruth Stoklund; Nilsen, Tom Ivar Lund; Haugeberg, Glenn; Bye, Anja; Kavanaugh, Arthur; Hoff, Mari (Journal article; Peer reviewed, 2018)Objective The aim of this study was to evaluate the impact of high intensity interval training (HIIT) on disease activity and patient disease perception in patients with psoriatic arthritis (PsA), and evaluating if a ... -
The therapeutic potential of high intensity interval training among women with lipedema
Sæther, Johanne (Master thesis, 2023)Bakgrunn Lipødem er en tilstand karakterisert med en symmetrisk sykelig fettansamling. Tilstanden er assosiert og forverres i kombinasjon med fedme. Smerte er en av de vanligste utfordringene og fører til nedsatt ...