Blar i NTNU Open på forfatter "Bergh, Sverre"
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Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk
Jansen, Iris E.; Savage, Jeanne E.; Watanabe, Kyoko; Bryois, Julien; Williams, Dylan M.; Steinberg, Stacy; Sealock, Julia; Karlsson, Ida K.; Hägg, Sara; Athanasiu, Lavinia; Voyle, Nicola; Proitsi, Petroula; Witoelar, Aree; Stringer, Sven; Aarsland, Dag; Almdahl, Ina Selseth; Andersen, Fred; Bergh, Sverre; Bettella, Francesco; Björnsson, Sigurbjörn; Brækhus, Anne; Bråthen, Geir; de Leeuw, Christiaan A.; Desikan, Rahul S.; Djurovic, Srdjan; Dumitrescu, Logan; Fladby, Tormod; Hohman, Timothy J.; Jónsson, Pálmi V.; Kiddle, Steven J; Rongve, Arvid; Saltvedt, Ingvild; Sando, Sigrid Botne; Selbæk, Geir; Shoai, Maryam; Skene, Nathan G.; Snædal, Jón G.; Stordal, Eystein; Ulstein, Ingun; Wang, Yunpeng; White, Linda Rosemary; Hardy, John; Hjerling-Leffler, Jens; Sullivan, Patrick; van der Flier, Wiesje M.; Dobson, Richard; Davis, Lea K; Stefánsson, Hreinn; Stefánsson, Kári; Pedersen, Nancy L; Ripke, Stephan; Andreassen, Ole Andreas; Posthuma, Danielle (Journal article; Peer reviewed, 2019)Alzheimer’s disease (AD) is highly heritable and recent studies have identified over 20 disease-associated genomic loci. Yet these only explain a small proportion of the genetic variance, indicating that undiscovered loci ... -
Geriatric assessment with management for older patients with cancer receiving radiotherapy. Protocol of a Norwegian cluster-randomised controlled pilot study
Røyset, Inga Marie; Saltvedt, Ingvild; Rostoft, Siri; Grønberg, Bjørn Henning; Kirkevold, Øyvind; Oldervoll, Line Merethe; Bye, Asta; Saltyte Benth, Jurate; Bergh, Sverre; Melby, Line; Halsteinli, Vidar; Døhl, Øystein; Røsstad, Tove Garåsen; Eriksen, Guro Falk; Sollid, May Ingvild Volungholen; Rolfson, Darryl; Jordhøy, Marit Slaaen (Journal article; Peer reviewed, 2021)About 50% of patients with cancer are expected to need radiotherapy (RT), and the majority of these are older. To improve outcomes for older patients with cancer, geriatric assessment (GA) with management (GAM) is highly ... -
Insomnia and risk of dementia in a large population-based study with 11-year follow-up: The HUNT study
Selbæk-Tungevåg, Selma; Selbæk, Geir; Strand, Bjørn Heine; Myrstad, Christian; Livingston, Gill; Lydersen, Stian; Bergh, Sverre; Ernstsen, Linda (Peer reviewed; Journal article, 2023)Despite evidence suggesting that insomnia is associated with the risk of dementia and cognitive dysfunction, studies have shown mixed results. Dementia has a long prodromal phase, and studies with long follow-up are required ... -
Meta-analysis of Alzheimer’s disease on 9,751 samples from Norway and IGAP study identifies four risk loci
Witoelar, Aree; Rongve, Arvid; Almdahl, Ina Selseth; Ulstein, Ingun; Engvig, Andreas; White, Linda Rosemary; Selbæk, Geir; Stordal, Eystein; Andersen, Fredrik; Brækhus, Anne; Saltvedt, Ingvild; Engedal, Knut; Hughes, Timothy; Bergh, Sverre; Bråthen, Geir; Bogdanovic, Nenad; Bettella, Francesco; Wang, Yunpeng; Athanasiu, Lavinia; Bahrami, Shahram; Le Hellard, Stephanie; Giddaluru, Sudheer; Dale, Anders M; Sando, Sigrid Botne; Steinberg, Stacy; Stefansson, Hreinn; Snaedal, Jon; Desikan, Rahul S; Stefansson, Kari; Aarsland, Dag; Djurovic, Srdjan; Fladby, Tormod; Andreassen, Ole Andreas (Journal article; Peer reviewed, 2018)A large fraction of genetic risk factors for Alzheimer’s Disease (AD) is still not identified, limiting the understanding of AD pathology and study of therapeutic targets. We conducted a genome-wide association study (GWAS) ... -
Midlife Physical Activity, Psychological Distress, and Dementia Risk: The HUNT Study
Zotcheva, Ekaterina; Bergh, Sverre; Selbæk, Geir; Krokstad, Steinar; Håberg, Asta; Strand, Bjørn Heine; Ernstsen, Linda (Journal article; Peer reviewed, 2018)Background: Physical activity (PA) is associated with a decreased dementia risk, whereas psychological distress (distress) is linked to an increased dementia risk. Objective: We investigated independent and joint ... -
Mobility and cognition at admission to the nursing home – a cross-sectional study
Sverdrup, Karen; Bergh, Sverre; Selbæk, Geir; Røen, Irene Mari; Kirkevold, Øyvind; Tangen, Gro Gujord (Journal article; Peer reviewed, 2018)Background Earlier studies show that the main reasons for admission to long-term nursing home care are cognitive impairment and functional impairments of activities of daily life. However, descriptive evidence of mobility ... -
Modifiable factors affecting older patients' quality of life and physical function during cancer treatment
Kirkhus, Lene; Harneshaug, Magnus; Saltyte Benth, Jurate; Grønberg, Bjørn Henning; Rostoft, Siri; Bergh, Sverre; Hjermstad, Marianne Jensen; Selbæk, Geir; Wyller, Torgeir Bruun; Kirkevold, Øyvind; Borza, Tom; Saltvedt, Ingvild; Jordhøy, Marit Slaaen (Journal article; Peer reviewed, 2019)Background Maintaining physical function and quality of life (QoL) are prioritized outcomes among older adults. We aimed to identify potentially modifiable factors affecting older patients' physical function and QoL ... -
Neuropsychiatric Symptoms in Persons with Dementia before and after Admission to Nursing Homes
Mukilvannan, Gardinija; Skånøy, Berit Sofie Jonassen (Master thesis, 2022)Målsetting: Målsettingen med denne studien var å beskrive nevropsykiatriske symptomer (NPS) hos personer med demens før og i løpet av den første måneden etter ankomst til sykehjem. Videre ønsket vi å undersøke faktorer ... -
Neuropsychiatric Symptoms in Persons with Dementia before and after Admission to Nursing Homes
Skånøy, Berit Sofie Jonassen; Mukilvannan, Gardinija (Master thesis, 2022)Målsetting: Målsettingen med denne studien var å beskrive nevropsykiatriske symptomer (NPS) hos personer med demens før og i løpet av den første måneden etter ankomst til sykehjem. Videre ønsket vi å undersøke faktorer ... -
Pain and quality of life in nursing home residents with dementia after admission – a longitudinal study
Helvik, Anne-Sofie; Bergh, Sverre; Saltyte Benth, Jurate; Borza, Tom; Husebø, Bettina Elisabeth Franziska; Tevik, Kjerstin Elisabeth (Peer reviewed; Journal article, 2023)Background Pain in nursing home (NH) residents with dementia is commonly reported and may affect Quality of Life (QoL) negatively. Few longitudinal studies have explored how pain and QoL develop in NH residents with ... -
Pain and quality of life in nursing home residents with dementia after admission – a longitudinal study
Helvik, Anne-Sofie; Bergh, Sverre; Saltyte Benth, Jurate; Borza, Tom; Husebø, Bettina Elisabeth Franziska; Tevik, Kjerstin Elisabeth (Peer reviewed; Journal article, 2023)Pain in nursing home (NH) residents with dementia is commonly reported and may affect Quality of Life (QoL) negatively. Few longitudinal studies have explored how pain and QoL develop in NH residents with dementia starting ... -
Pain in nursing home residents with dementia and its association to quality of life
Helvik, Anne-Sofie; Bergh, Sverre; Šaltytė Benth, Jūratė; Selbæk, Geir; Husebø, Bettina Elisabeth Franziska; Tevik, Kjerstin Elisabeth (Peer reviewed; Journal article, 2021)Abstract Objectives We aimed to describe pain, use of analgesics and quality of life (QoL) in people with dementia admitted to a Norwegian nursing home (NH), and to explore if and how pain was associated with their QoL ... -
Physical performance across the cognitive spectrum and between dementia subtypes in a population-based sample of older adults: The HUNT study
Sverdrup, Karen; Selbæk, Geir; Bergh, Sverre; Strand, Bjørn Heine; Thingstad, Pernille; Skjellegrind, Håvard; Skjerve, Kjerstin Næss; Tangen, Gro Gujord (Journal article; Peer reviewed, 2021)Background: Literature on physical performance in older adults across the cognitive spectrum remains inconclusive, and knowledge on differences between dementia subtypes is lacking. We aim to identify distinct physical-performance ... -
Predictors for Nursing Home Admission and Death among Community-Dwelling People 70 Years and Older Who Receive Domiciliary Care
Wergeland, Jon Normann; Selbæk, Geir; Bergh, Sverre; Söderhamn, Ulrika; Kirkevold, Øyvind (Journal article; Peer reviewed, 2015)Aim: The aim of this study was to analyze which variables predicted nursing home admission (NHA) and death. Methods: 1,001 recipients of domiciliary care were assessed three times in a 3-year period. Through bivariate and ... -
Prevalence and persistent prescription of analgesic drugs in persons admitted with dementia to a nursing home - A longitudinal study
Helvik, Anne-Sofie; Bergh, Sverre; Kabukcuoglu, Kamile; Saltyte Benth, Jurate; Lichtwarck, Bjørn; Husebø, Bettina Elisabeth Franziska; Tevik, Kjerstin Elisabeth (Peer reviewed; Journal article, 2022)The overall aim was to explore the prevalence and persistent regular prescription of opioids and paracetamol among nursing home (NH) residents with dementia at admission and over time. A total of 996 residents with dementia, ... -
Prevalence and persistent use of analgesic drugs in older adults receiving domiciliary care at baseline - a longitudinal study
Tevik, Kjerstin Elisabeth; Saltyte Benth, Jurate; Aarøen, Marte Kristensen; Lornstad, Marie Turmo; Bergh, Sverre; Helvik, Anne-Sofie (Peer reviewed; Journal article, 2021)Aims To describe the prevalence and persistence of analgesic drug use (opioids and antipyretics [ie, paracetamol and acetylsalicylic acid]) in participants (≥70 years) with and without dementia receiving domiciliary care ... -
Prevalence and persistent use of psychotropic drugs in older adults receiving domiciliary care at baseline
Lornstad, Marie Turmo; Aarøen, Marte; Bergh, Sverre; Saltyte Benth, Jurate; Helvik, Anne-Sofie (Journal article; Peer reviewed, 2019)Background Little is known about the use of psychotropic drugs in older adults receiving domiciliary care. The first aim was to describe the prevalence and persistency of use of psychotropic drugs in older adults (≥ 70 years) ... -
The Reliability and Validity of the Norwegian Version of the Quality of Life in Late-Stage Dementia Scale
Røen, Irene Mari; Selbæk, Geir; Kirkevold, Øyvind; Engedal, Knut; Lerdal, Anners; Bergh, Sverre (Journal article, 2015)Aim: To translate the Quality of Life in Late-Stage Dementia (QUALID) Scale into Norwegian, and to evaluate the test-retest reliability and validity of the scale. Method: QUALID was translated according to standardised ... -
Resource Use and Disease Course in dementia - Nursing Home (REDIC-NH), a longitudinal cohort study; design and patient characteristics at admission to Norwegian nursing homes
Røen, Irene Mari; Selbæk, Geir; Kirkevold, Øyvind; Engedal, Knut; Testad, Ingelin; Bergh, Sverre (Journal article; Peer reviewed, 2017)Background Earlier studies of nursing home patients show a high prevalence of dementia, neuropsychiatric symptoms (NPS), pain, and dependency in activities of daily living. The REDIC-NH cohort was set up to study the disease ... -
Safety and efficacy of plasma transfusion from exercise - trained donors in patients with early Alzheimer’s disease: protocol for the ExPlas study
Tari, Atefe R; Berg, Helene Haugen; Videm, Vibeke; Bråthen, Geir; White, Linda Rosemary; Røsbjørgen, Ragnhild; Scheffler, Katja; Dalen, Håvard; Holte, Espen; Håberg, Asta Kristine; Selbæk, Geir; Lydersen, Stian; Duezel, Emrah; Bergh, Sverre; Logan-halvorsrud, Kjell Rune; Sando, Sigrid Botne; Wisløff, Ulrik (Peer reviewed; Journal article, 2022)Introduction Given that exercise training reduces the risk of developing Alzheimer’s disease (AD), induces changes in the blood composition and has widespread systemic benefits, it is reasonable to hypothesise that exercised ...