Blar i NTNU Open på forfatter "Greven, Johannes"
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Liquid Biopsy in Organ Damage: small extracellular vesicle chip-based assessment of polytrauma
Wang, Bingduo; Wöhler, Aliona; Greven, Johannes; Salzmann, Rebekka J. S.; Keller, Cindy M.; Tertel, Tobias; Zhao, Qun; Mert, Ümit; Horst, Klemens; Lupu, Ludmila; Huber-Lang, Markus; van Griensven, Martijn; Mollnes, Tom Erik; Schaaf, Sebastian; Schwab, Robert; Strassburg, Christian P.; Schmidt-Wolf, Ingo G. H.; Giebel, Bernd; Hildebrand, Frank; Lukacs-Kornek, Veronika; Willms, Arnulf G.; Kornek, Miroslaw T. (Journal article; Peer reviewed, 2023)Background Despite major advances in medicine, blood-borne biomarkers are urgently needed to support decision-making, including polytrauma. Here, we assessed serum-derived extracellular vesicles (EVs) as potential markers ... -
Simultaneous C5 and CD14 inhibition limits inflammation and organ dysfunction in pig polytrauma
Lupu, Ludmila; Horst, Klemens; Greven, Johannes; Mert, Ümit; Ludviksen, Judith K; Pettersen, Kristin; Lau, Corinna; Li, Yang; Palmer, Annette; Qin, Kang; Zhang, Xing; Mayer, Benjamin; van Griensven, Martijn; Huber-Lang, Markus; Hildebrand, Frank; Mollnes, Tom Eirik (Peer reviewed; Journal article, 2022)Dysfunctional complement activation and Toll-like receptor signaling immediately after trauma are associated with development of trauma-induced coagulopathy and multiple organ dysfunction syndrome. We assessed the efficacy ...