Browsing NTNU Open by Author "Liu, Tengzhi"
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Copper-64 radiopharmaceuticals for theranostics of hypoxic tumors
Liu, Tengzhi (Doctoral theses at NTNU;2023:318, Doctoral thesis, 2023)English summary Tumor hypoxia (oxygen deficiency) is a poor indicator in cancer as it associates with disease progression, recurrence, metastasis, and treatment resistance. Hypoxia occurs in most solid tumors, however, ... -
Development of an automated production process of [<sup>64</sup>Cu][Cu (ATSM)] for positron emission tomography imaging and theranostic applications
Liu, Tengzhi; Redalen, Kathrine; Karlsen, Morten (Peer reviewed; Journal article, 2022)Cyclotron-produced copper-64 radioisotope tracers offer the possibility to perform both diagnostic investigation by positron emission tomography (PET) and radiotherapy by a theranostic approach with bifunctional chelators. ... -
Functionalization of Silica Aerogels and AlPO-5 with Molybdenum, Rhenium - A Study on Metal Introduction Methods
Liu, Tengzhi (Master thesis, 2018)In the present work possible routes for the introduction of Mo and Re into silica aerogels and aluminophosphate AlPO-5 have been investigated. Parameter studies on the influence of synthesis conditions including metal ... -
Hypoxia imaging and theranostic potential of [64Cu][Cu(ATSM)] and ionic Cu(II) salts: a review of current evidence and discussion of the retention mechanisms
Liu, Tengzhi; Karlsen, Morten; Karlberg, Anna Maria; Redalen, Kathrine (Peer reviewed; Journal article, 2020)Background Tumor hypoxia (low tissue oxygenation) is an adverse condition of the solid tumor environment, associated with malignant progression, radiotherapy resistance, and poor prognosis. One method to detect tumor ... -
Preclinical studies of Cu-64 radiopharmaceuticals for theranostics of hypoxic tumors
Dahle, Maria Aanesland (Master thesis, 2021)Abstract will be available on 2024-08-26