Browsing NTNU Open by Author "Høydal, Morten Andre"
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Aerobic interval training partly reverse contractile dysfunction and impaired Ca2+ handling in atrial myocytes from rats with post infarction heart failure
Johnsen, Anne Berit; Høydal, Morten Andre; Røsbjørgen, Ragnhild; Stølen, Tomas; Wisløff, Ulrik (Journal article; Peer reviewed, 2013)Background: There is limited knowledge about atrial myocyte Ca2+ handling in the failing hearts. The aim of this study was to examine atrial myocyte contractile function and Ca2+ handling in rats with post-infarction heart ... -
Atrial Myocyte Function and Ca2+ Handling Is Associated with Inborn Aerobic Capacity
Johnsen, Anne Berit; Rolim, Natale Pinheiro Lage; Stølen, Tomas; Alves, Marcia; Sousa, Mirta; Slupphaug, Geir; Britton, Steven L; Koch, Lauren G; Smith, Godfrey L; Wisløff, Ulrik; Høydal, Morten Andre (Peer reviewed; Journal article, 2013-10-16)Background: Although high aerobic capacity is associated with effective cardiac function, the effect of aerobic capacity on atrial function, especially in terms of cellular mechanisms, is not known. We aimed to investigate ... -
Exploring the cardioprotective effects of miR-210 in doxorubicin-treated cardiomyocytes
Øiaas, Mikal Solstad (Master thesis, 2024)Bakgrunn: Doxorubicin (DOX) er et mye brukt kreftlegemiddel. På grunn av betydelig kardiotoksisitet må den kumulative dosen kontrolleres nøye. Studier har vist at mikroRNA-210 (miR-210) kan ha en beskyttende effekt på ... -
NF-κB Transcriptional Activity Indispensably Mediates Hypoxia–Reoxygenation Stress-Induced microRNA-210 Expression
Marwarha, Gurdeep Singh Atamjit; Slagsvold, Katrine Hordnes; Høydal, Morten Andre (Peer reviewed; Journal article, 2023)Ischemia–reperfusion (I-R) injury is a cardinal pathophysiological hallmark of ischemic heart disease (IHD). Despite significant advances in the understanding of what causes I-R injury and hypoxia–reoxygenation (H-R) stress, ...