CASCADE 2.0 analysis using pint, bioLQM and MaBoSS

import ginsim
import biolqm
import maboss
import pypint
from pypint import Goal
from colomoto_jupyter import tabulate
import pandas as pd
import sys
import itertools

This notebook has been executed using the docker image colomoto/colomoto-docker:2022-07-01

Generic model CASCADE 2.0

#Load your model
generic_model = ginsim.load("/tmp/colomoto49z40uzm_20180116_generic_in-silico-model.zginml")
generic_lqm = ginsim.to_biolqm(generic_model)

BioLQM perturbation all the nodes against each other

For discovery of the suitable combination that have synergy effect by calculating the growth

perturbations = [" SRC%0"," CSK%0"," CHUK%0"," RAC_f%0"," DUSP1%0"," TGFBR2%0"," ILR_f%0"," SYK%0"," IRAK1%0"," SHC1%0"," JAK_f%0"," CBPp300_c%0"," SKP2%0"," TP53%0"," SMAD7%0"," SMAD6%0"," DKK_f%0"," FOXO_f%0"," TCF7_f%0"," DKK_g%0"," MYC%0"," CCND1%0"," EGR1%0"," MMP_f%0"," PTEN_g%0"," RTPK_f%0"," CTNNB1%0","LEF1%0","SFRP1%0","FZD_f%0"," CASP8%0"," REL_f%0"," NFKB_f%0"," DVL_f%0"," LRP_f%0"," BTRC%0"," CK1_f%0"," AXIN1%0"," mTORC2_c%0"," PDPK1%0"," MEK_f%0"," CYCS%0"," CASP9%0"," GSK3_f%0"," IRS1%0"," MDM2%0"," AKT_f%0"," BCL2%0"," RAF_f%0"," mTORC1_c%0"," RHEB%0"," RTPK_g%0"," PTEN%0"," CASP3%0"," PIK3CA%0"," CREBBP%0"," PTPN11%0"," KRAS%0"," MAP2K4%0"," MAP2K7%0"," MAPK14%0"," JNK_f%0"," MAP2K3%0"," ERK_f%0"," LIF%0"," PPP1CA%0"," GAB_f%0"," SOS1%0"," PRKCA%0"," VAV1%0"," PLCG1%0"," PRKCD%0"," RSK_f%0"," S6K_f%0"," PLK1%0"," ILK%0"," SOCS1%0"," DUSP6%0"," STAT3%0"," LIMK2%0"," EP300%0"," STAT1%0"," IKBKB%0"," SRF%0"," PIAS1%0"," TRAF6%0"," SOCS1_g%0"," ISGF3_c%0"," STAT2%0"," CFLAR%0"," SMAD2%0"," MDM2_g%0"," BAX%0"," PRKACA%0"," TGFB1%0"," MAP3K8%0"," TSC_f%0"," SMAD4%0"," BAD%0"," MAP3K5%0"," AKT1S1%0"," SKI%0"," SMAD3%0"," MAPKAPK2%0"," DUSP1_g%0"," MSK_f%0"," GRAP2%0"," TAB_f%0"," ATF2%0"," SMAD5%0"," SMAD1%0"," FOS%0"," JUN%0"," MAP3K7%0"," NLK%0"," SMAD7_g%0"," SMAD6_g%0"," AP1_c%0"," ACVR1%0"," PTPN6%0"," CDC42%0"," GRB2%0"," TGFBR1%0"," SMURF1%0"," SMURF2%0"," RHOA%0"," BMPR2%0"," PARD6A%0"," DAAM1%0"," SFRP1_g%0"," PPM1A%0"," CFL_f%0"," PAK1%0"," MAP3K11%0"," MAP3K4%0"," LIMK1%0"," ROCK1%0"," ITCH%0"," ARHGAP24%0"," TIAM1%0"," RND3%0"," MAPK8IP3%0"," MXD1%0"," PIP3%0"]

single perturbation for all the nodes

to compare the growth between the single and double perturbation to find the synergiesed combination

'''Define dictionaries to store attractors for each perturbation'''
fixpointlist = {}

'''trapspacelist is used for perturbations where no stable state is found
    to find eventual cyclic attractors.'''
trapspacelist = {}

for p in perturbations:
    fixpoints = biolqm.fixpoints(biolqm.perturbation(generic_lqm, p))
    if(fixpoints):
        fixpointlist[p] = fixpoints
    else:
        '''No stable state found, so we look for cycles'''
        trapspace = biolqm.trapspace(biolqm.perturbation(generic_lqm, p))
        trapspacelist[p] = trapspace

#see attractors in tabulated tables for each perturbation
for k, v in fixpointlist.items():
    print(k)
    sys.displayhook(tabulate(v))
    print()
    
for k, v in trapspacelist.items():
    print(k)
    sys.displayhook(tabulate(v))
    print()

 SRC%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 CSK%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	0	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 CHUK%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 RAC_f%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 DUSP1%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	1	0	1	0	1	1	1	1	0	1	0	0	0	0	0	1	2	1	1	0	1	0	1	0	0	1	1	1	0	1	1	1	0	0	0	1	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	1	0	1	0	1	1	1	1	0	0	0	0	1	1	1	1	1	0	0	1	0	0	0	1	0	0	0	0	1	1	1	0	0	1	0	0	1	0	1	1	0	0	0	1	1	1	1	0	1	1	1	0	0	1	0	0	1	1	0	0	0	0	1	1	0	0	0	1	0	0	0	1	1	0	1	1	1	0	0	0	1	1	1	1	0	1	1	1	0

 TGFBR2%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 ILR_f%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 SYK%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 IRAK1%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 SHC1%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 JAK_f%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 CBPp300_c%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 SKP2%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 TP53%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 SMAD7%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 SMAD6%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 DKK_f%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 FOXO_f%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	1	0	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 TCF7_f%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 DKK_g%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 MYC%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 CCND1%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	0	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	0	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 EGR1%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	0	1	0	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 MMP_f%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	0	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 PTEN_g%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	0	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 RTPK_f%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 CTNNB1%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

LEF1%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

SFRP1%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	0	1	1	1	1	1	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	1	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

FZD_f%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 CASP8%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	1	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	0	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	0	1	1	0	1	0	0	0	1	0	1	0	1	0	0	0	0	0	0	0	0	0	0	0	1	1	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	1	1	1	1	0	0	0	1	0	0	1	0

 REL_f%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	0	0	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	0	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 NFKB_f%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	0	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	0	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 DVL_f%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 LRP_f%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	0	0	1	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 BTRC%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 CK1_f%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 AXIN1%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 mTORC2_c%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	0	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 PDPK1%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 MEK_f%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 CYCS%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 CASP9%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 GSK3_f%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 IRS1%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	0	0	0	0	0	0	0	1	0	0	0	0	1	3	1	1	1	0	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 MDM2%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	1	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	1	1	0	1	0	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	1	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 AKT_f%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 BCL2%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 RAF_f%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 mTORC1_c%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 RHEB%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	0	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 RTPK_g%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	0	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 PTEN%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	0	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	0	1	0	0	0	1	1	0	1	0	1	1	1	0

 CASP3%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	1	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	0	1	1	0	1	0	0	0	1	0	1	0	1	0	0	0	0	0	0	0	0	0	0	0	1	1	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	1	1	1	1	0	0	0	1	0	0	1	0

 PIK3CA%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	0	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	0	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 CREBBP%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 PTPN11%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 KRAS%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 MAP2K4%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 MAP2K7%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	0	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 JNK_f%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 ERK_f%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 LIF%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 PPP1CA%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 GAB_f%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 SOS1%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 PRKCA%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 VAV1%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 PLCG1%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 PRKCD%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	0	0	0	1	0	0	0	1	1	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 RSK_f%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 S6K_f%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 PLK1%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 ILK%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 SOCS1%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 DUSP6%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 STAT3%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	0	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	0	1	0	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	0	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 LIMK2%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 EP300%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 STAT1%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 IKBKB%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 SRF%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	0	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 PIAS1%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	0	0	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	1	0	1	0	0	1	0	1	0	0	1	0	0	0	0	0	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 TRAF6%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 SOCS1_g%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 ISGF3_c%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 STAT2%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 CFLAR%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 SMAD2%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 MDM2_g%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	0	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 BAX%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 PRKACA%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	0	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	0	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 TGFB1%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 MAP3K8%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 TSC_f%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 SMAD4%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 BAD%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	1	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	0	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 AKT1S1%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	1	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	1	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	0	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 SKI%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	1	1	1	1	0	0	1	1	1	0	0	0	1	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 SMAD3%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 DUSP1_g%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	0	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 MSK_f%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	0	0	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	0	0	1	0	0	0	0	1	1	1	1	0	1	1	0	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 GRAP2%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 TAB_f%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 ATF2%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 SMAD5%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 SMAD1%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 FOS%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	0	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 JUN%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 MAP3K7%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 NLK%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 SMAD7_g%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 SMAD6_g%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 AP1_c%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 ACVR1%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 PTPN6%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 CDC42%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 GRB2%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 TGFBR1%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 SMURF1%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 SMURF2%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	0	1	0	0	0	0	0	0	0	0	0	1	0	0	2	0	0	0	0	1	0	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	1	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	1	0	0	0	0	0	1	0	0	1	0	0	0	0	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	0	0	0	0	0	1	0	0	0	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0
1	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 RHOA%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 BMPR2%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 PARD6A%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 DAAM1%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 SFRP1_g%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	0	1	1	1	1	1	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	1	0	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 PPM1A%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	0	1	0	0	0	1	1	0	1	0	1	1	1	0

 CFL_f%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	0	0	0	0	1	1	0	1	0	1	1	1	0

 PAK1%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 MAP3K11%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 MAP3K4%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 LIMK1%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	0	0	0	0	0	1	0	1	0	1	1	1	0

 ROCK1%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	1	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	1	0	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	1	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	1	1	1	1	0	0	0	1	0	0	1	0

 ITCH%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 ARHGAP24%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	1	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	1	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	1	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	1	1	1	1	1	0	0	0	1	1	1	0

 TIAM1%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 RND3%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	0	1	1	0

 MAPK8IP3%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	0	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	0	1	0

 MXD1%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	2	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	1	1	1	1	1	0	0	0	0	1	1	1	1	1	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	1	0	1	1	0	0	0	1	1	0	1	0	1	1	0	0

 PIP3%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 MAPK14%0

	SRC	CSK	CHUK	RAC_f	Prosurvival_b1	Prosurvival_b2	Prosurvival_b3	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f_b1	FOXO_f_b2	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival_b1	Antisurvival_b2	Antisurvival_b3	Antisurvival_b4	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	1	1	0	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	0	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	0	254	254	1	254	0	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254

 MAP2K3%0

	SRC	CSK	CHUK	RAC_f	Prosurvival_b1	Prosurvival_b2	Prosurvival_b3	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f_b1	FOXO_f_b2	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival_b1	Antisurvival_b2	Antisurvival_b3	Antisurvival_b4	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	0	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254

 MAP3K5%0

	SRC	CSK	CHUK	RAC_f	Prosurvival_b1	Prosurvival_b2	Prosurvival_b3	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f_b1	FOXO_f_b2	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival_b1	Antisurvival_b2	Antisurvival_b3	Antisurvival_b4	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	0	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254

 MAPKAPK2%0

	SRC	CSK	CHUK	RAC_f	Prosurvival_b1	Prosurvival_b2	Prosurvival_b3	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f_b1	FOXO_f_b2	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival_b1	Antisurvival_b2	Antisurvival_b3	Antisurvival_b4	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	0	0	1	0	0	0	0	0	0	0	0	254	0	0	0	1	1	0	0	0	1	1	1	1	0	0	0	1	0	1	0	0	0	1	0	0	0	1	0	0	254	254	0	1	254	0	0	0	0	1	1	1	1	0	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	0	0	1	0	1	0	0	1	0	1	0	0	1	0	0	0	0	254	254	1	0	0	0	0	1	1	1	1	0	0	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

Double perturbation all the nodes against each other

# Perform double perturbations - All against all
all_pairwise = itertools.permutations(perturbations, 2)
all_pairwise_list = list(all_pairwise)
all_pairwise_list = str(all_pairwise_list).replace(',', ' ')
all_pairwise_list

"[(' SRC%0'  ' CSK%0')  (' SRC%0'  ' CHUK%0')  (' SRC%0'  ' RAC_f%0')  (' SRC%0'  ' DUSP1%0')  (' SRC%0'  ' TGFBR2%0')  (' SRC%0'  ' ILR_f%0')  (' SRC%0'  ' SYK%0')  (' SRC%0'  ' IRAK1%0')  (' SRC%0'  ' SHC1%0')  (' SRC%0'  ' JAK_f%0')  (' SRC%0'  ' CBPp300_c%0')  (' SRC%0'  ' SKP2%0')  (' SRC%0'  ' TP53%0')  (' SRC%0'  ' SMAD7%0')  (' SRC%0'  ' SMAD6%0')  (' SRC%0'  ' DKK_f%0')  (' SRC%0'  ' FOXO_f%0')  (' SRC%0'  ' TCF7_f%0')  (' SRC%0'  ' DKK_g%0')  (' SRC%0'  ' MYC%0')  (' SRC%0'  ' CCND1%0')  (' SRC%0'  ' EGR1%0')  (' SRC%0'  ' MMP_f%0')  (' SRC%0'  ' PTEN_g%0')  (' SRC%0'  ' RTPK_f%0')  (' SRC%0'  ' CTNNB1%0')  (' SRC%0'  'LEF1%0')  (' SRC%0'  'SFRP1%0')  (' SRC%0'  'FZD_f%0')  (' SRC%0'  ' CASP8%0')  (' SRC%0'  ' REL_f%0')  (' SRC%0'  ' NFKB_f%0')  (' SRC%0'  ' DVL_f%0')  (' SRC%0'  ' LRP_f%0')  (' SRC%0'  ' BTRC%0')  (' SRC%0'  ' CK1_f%0')  (' SRC%0'  ' AXIN1%0')  (' SRC%0'  ' mTORC2_c%0')  (' SRC%0'  ' PDPK1%0')  (' SRC%0'  ' MEK_f%0')  (' SRC%0'  ' CYCS%0')  (' SRC%0'  ' CASP9%0')  (' SRC%0'  ' GSK3_f%0')  (' SRC%0'  ' IRS1%0')  (' SRC%0'  ' MDM2%0')  (' SRC%0'  ' AKT_f%0')  (' SRC%0'  ' BCL2%0')  (' SRC%0'  ' RAF_f%0')  (' SRC%0'  ' mTORC1_c%0')  (' SRC%0'  ' RHEB%0')  (' SRC%0'  ' RTPK_g%0')  (' SRC%0'  ' PTEN%0')  (' SRC%0'  ' CASP3%0')  (' SRC%0'  ' PIK3CA%0')  (' SRC%0'  ' CREBBP%0')  (' SRC%0'  ' PTPN11%0')  (' SRC%0'  ' KRAS%0')  (' SRC%0'  ' MAP2K4%0')  (' SRC%0'  ' MAP2K7%0')  (' SRC%0'  ' MAPK14%0')  (' SRC%0'  ' JNK_f%0')  (' SRC%0'  ' MAP2K3%0')  (' SRC%0'  ' ERK_f%0')  (' SRC%0'  ' LIF%0')  (' SRC%0'  ' PPP1CA%0')  (' SRC%0'  ' GAB_f%0')  (' SRC%0'  ' SOS1%0')  (' SRC%0'  ' PRKCA%0')  (' SRC%0'  ' VAV1%0')  (' SRC%0'  ' PLCG1%0')  (' SRC%0'  ' PRKCD%0')  (' SRC%0'  ' RSK_f%0')  (' SRC%0'  ' S6K_f%0')  (' SRC%0'  ' PLK1%0')  (' SRC%0'  ' ILK%0')  (' SRC%0'  ' SOCS1%0')  (' SRC%0'  ' DUSP6%0')  (' SRC%0'  ' STAT3%0')  (' SRC%0'  ' LIMK2%0')  (' SRC%0'  ' EP300%0')  (' SRC%0'  ' STAT1%0')  (' SRC%0'  ' IKBKB%0')  (' SRC%0'  ' SRF%0')  (' SRC%0'  ' PIAS1%0')  (' SRC%0'  ' TRAF6%0')  (' SRC%0'  ' SOCS1_g%0')  (' SRC%0'  ' ISGF3_c%0')  (' SRC%0'  ' STAT2%0')  (' SRC%0'  ' CFLAR%0')  (' SRC%0'  ' SMAD2%0')  (' SRC%0'  ' MDM2_g%0')  (' SRC%0'  ' BAX%0')  (' SRC%0'  ' PRKACA%0')  (' SRC%0'  ' TGFB1%0')  (' SRC%0'  ' MAP3K8%0')  (' SRC%0'  ' TSC_f%0')  (' SRC%0'  ' SMAD4%0')  (' SRC%0'  ' BAD%0')  (' SRC%0'  ' MAP3K5%0')  (' SRC%0'  ' AKT1S1%0')  (' SRC%0'  ' SKI%0')  (' SRC%0'  ' SMAD3%0')  (' SRC%0'  ' MAPKAPK2%0')  (' SRC%0'  ' DUSP1_g%0')  (' SRC%0'  ' MSK_f%0')  (' SRC%0'  ' GRAP2%0')  (' SRC%0'  ' TAB_f%0')  (' SRC%0'  ' ATF2%0')  (' SRC%0'  ' SMAD5%0')  (' SRC%0'  ' SMAD1%0')  (' SRC%0'  ' FOS%0')  (' SRC%0'  ' JUN%0')  (' SRC%0'  ' MAP3K7%0')  (' SRC%0'  ' NLK%0')  (' SRC%0'  ' SMAD7_g%0')  (' SRC%0'  ' SMAD6_g%0')  (' SRC%0'  ' AP1_c%0')  (' SRC%0'  ' ACVR1%0')  (' SRC%0'  ' PTPN6%0')  (' SRC%0'  ' CDC42%0')  (' SRC%0'  ' GRB2%0')  (' SRC%0'  ' TGFBR1%0')  (' SRC%0'  ' SMURF1%0')  (' SRC%0'  ' SMURF2%0')  (' SRC%0'  ' RHOA%0')  (' SRC%0'  ' BMPR2%0')  (' SRC%0'  ' PARD6A%0')  (' SRC%0'  ' DAAM1%0')  (' SRC%0'  ' SFRP1_g%0')  (' SRC%0'  ' PPM1A%0')  (' SRC%0'  ' CFL_f%0')  (' SRC%0'  ' PAK1%0')  (' SRC%0'  ' MAP3K11%0')  (' SRC%0'  ' MAP3K4%0')  (' SRC%0'  ' LIMK1%0')  (' SRC%0'  ' ROCK1%0')  (' SRC%0'  ' ITCH%0')  (' SRC%0'  ' ARHGAP24%0')  (' SRC%0'  ' TIAM1%0')  (' SRC%0'  ' RND3%0')  (' SRC%0'  ' MAPK8IP3%0')  (' SRC%0'  ' MXD1%0')  (' SRC%0'  ' PIP3%0')  (' CSK%0'  ' SRC%0')  (' CSK%0'  ' CHUK%0')  (' CSK%0'  ' RAC_f%0')  (' CSK%0'  ' DUSP1%0')  (' CSK%0'  ' TGFBR2%0')  (' CSK%0'  ' ILR_f%0')  (' CSK%0'  ' SYK%0')  (' CSK%0'  ' IRAK1%0')  (' CSK%0'  ' SHC1%0')  (' CSK%0'  ' JAK_f%0')  (' CSK%0'  ' CBPp300_c%0')  (' CSK%0'  ' SKP2%0')  (' CSK%0'  ' TP53%0')  (' CSK%0'  ' SMAD7%0')  (' CSK%0'  ' SMAD6%0')  (' CSK%0'  ' DKK_f%0')  (' CSK%0'  ' FOXO_f%0')  (' CSK%0'  ' TCF7_f%0')  (' CSK%0'  ' DKK_g%0')  (' CSK%0'  ' MYC%0')  (' CSK%0'  ' CCND1%0')  (' CSK%0'  ' EGR1%0')  (' CSK%0'  ' MMP_f%0')  (' CSK%0'  ' PTEN_g%0')  (' CSK%0'  ' RTPK_f%0')  (' CSK%0'  ' CTNNB1%0')  (' CSK%0'  'LEF1%0')  (' CSK%0'  'SFRP1%0')  (' CSK%0'  'FZD_f%0')  (' CSK%0'  ' CASP8%0')  (' CSK%0'  ' REL_f%0')  (' CSK%0'  ' NFKB_f%0')  (' CSK%0'  ' DVL_f%0')  (' CSK%0'  ' LRP_f%0')  (' CSK%0'  ' BTRC%0')  (' CSK%0'  ' CK1_f%0')  (' CSK%0'  ' AXIN1%0')  (' CSK%0'  ' mTORC2_c%0')  (' CSK%0'  ' PDPK1%0')  (' CSK%0'  ' MEK_f%0')  (' CSK%0'  ' CYCS%0')  (' CSK%0'  ' CASP9%0')  (' CSK%0'  ' GSK3_f%0')  (' CSK%0'  ' IRS1%0')  (' CSK%0'  ' MDM2%0')  (' CSK%0'  ' AKT_f%0')  (' CSK%0'  ' BCL2%0')  (' CSK%0'  ' RAF_f%0')  (' CSK%0'  ' mTORC1_c%0')  (' CSK%0'  ' RHEB%0')  (' CSK%0'  ' RTPK_g%0')  (' CSK%0'  ' PTEN%0')  (' CSK%0'  ' CASP3%0')  (' CSK%0'  ' PIK3CA%0')  (' CSK%0'  ' CREBBP%0')  (' CSK%0'  ' PTPN11%0')  (' CSK%0'  ' KRAS%0')  (' CSK%0'  ' MAP2K4%0')  (' CSK%0'  ' MAP2K7%0')  (' CSK%0'  ' MAPK14%0')  (' CSK%0'  ' JNK_f%0')  (' CSK%0'  ' MAP2K3%0')  (' CSK%0'  ' ERK_f%0')  (' CSK%0'  ' LIF%0')  (' CSK%0'  ' PPP1CA%0')  (' CSK%0'  ' GAB_f%0')  (' CSK%0'  ' SOS1%0')  (' CSK%0'  ' PRKCA%0')  (' CSK%0'  ' VAV1%0')  (' CSK%0'  ' PLCG1%0')  (' CSK%0'  ' PRKCD%0')  (' CSK%0'  ' RSK_f%0')  (' CSK%0'  ' S6K_f%0')  (' CSK%0'  ' PLK1%0')  (' CSK%0'  ' ILK%0')  (' CSK%0'  ' SOCS1%0')  (' CSK%0'  ' DUSP6%0')  (' CSK%0'  ' STAT3%0')  (' CSK%0'  ' LIMK2%0')  (' CSK%0'  ' EP300%0')  (' CSK%0'  ' STAT1%0')  (' CSK%0'  ' IKBKB%0')  (' CSK%0'  ' SRF%0')  (' CSK%0'  ' PIAS1%0')  (' CSK%0'  ' TRAF6%0')  (' CSK%0'  ' SOCS1_g%0')  (' CSK%0'  ' ISGF3_c%0')  (' CSK%0'  ' STAT2%0')  (' CSK%0'  ' CFLAR%0')  (' CSK%0'  ' SMAD2%0')  (' CSK%0'  ' MDM2_g%0')  (' CSK%0'  ' BAX%0')  (' CSK%0'  ' PRKACA%0')  (' CSK%0'  ' TGFB1%0')  (' CSK%0'  ' MAP3K8%0')  (' CSK%0'  ' TSC_f%0')  (' CSK%0'  ' SMAD4%0')  (' CSK%0'  ' BAD%0')  (' CSK%0'  ' MAP3K5%0')  (' CSK%0'  ' AKT1S1%0')  (' CSK%0'  ' SKI%0')  (' CSK%0'  ' SMAD3%0')  (' CSK%0'  ' MAPKAPK2%0')  (' CSK%0'  ' DUSP1_g%0')  (' CSK%0'  ' MSK_f%0')  (' CSK%0'  ' GRAP2%0')  (' CSK%0'  ' TAB_f%0')  (' CSK%0'  ' ATF2%0')  (' CSK%0'  ' SMAD5%0')  (' CSK%0'  ' SMAD1%0')  (' CSK%0'  ' FOS%0')  (' CSK%0'  ' JUN%0')  (' CSK%0'  ' MAP3K7%0')  (' CSK%0'  ' NLK%0')  (' CSK%0'  ' SMAD7_g%0')  (' CSK%0'  ' SMAD6_g%0')  (' CSK%0'  ' AP1_c%0')  (' CSK%0'  ' ACVR1%0')  (' CSK%0'  ' PTPN6%0')  (' CSK%0'  ' CDC42%0')  (' CSK%0'  ' GRB2%0')  (' CSK%0'  ' TGFBR1%0')  (' CSK%0'  ' SMURF1%0')  (' CSK%0'  ' SMURF2%0')  (' CSK%0'  ' RHOA%0')  (' CSK%0'  ' BMPR2%0')  (' CSK%0'  ' PARD6A%0')  (' CSK%0'  ' DAAM1%0')  (' CSK%0'  ' SFRP1_g%0')  (' CSK%0'  ' PPM1A%0')  (' CSK%0'  ' CFL_f%0')  (' CSK%0'  ' PAK1%0')  (' CSK%0'  ' MAP3K11%0')  (' CSK%0'  ' MAP3K4%0')  (' CSK%0'  ' LIMK1%0')  (' CSK%0'  ' ROCK1%0')  (' CSK%0'  ' ITCH%0')  (' CSK%0'  ' ARHGAP24%0')  (' CSK%0'  ' TIAM1%0')  (' CSK%0'  ' RND3%0')  (' CSK%0'  ' MAPK8IP3%0')  (' CSK%0'  ' MXD1%0')  (' CSK%0'  ' PIP3%0')  (' CHUK%0'  ' SRC%0')  (' CHUK%0'  ' CSK%0')  (' CHUK%0'  ' RAC_f%0')  (' CHUK%0'  ' DUSP1%0')  (' CHUK%0'  ' TGFBR2%0')  (' CHUK%0'  ' ILR_f%0')  (' CHUK%0'  ' SYK%0')  (' CHUK%0'  ' IRAK1%0')  (' CHUK%0'  ' SHC1%0')  (' CHUK%0'  ' JAK_f%0')  (' CHUK%0'  ' CBPp300_c%0')  (' CHUK%0'  ' SKP2%0')  (' CHUK%0'  ' TP53%0')  (' CHUK%0'  ' SMAD7%0')  (' CHUK%0'  ' SMAD6%0')  (' CHUK%0'  ' DKK_f%0')  (' CHUK%0'  ' FOXO_f%0')  (' CHUK%0'  ' TCF7_f%0')  (' CHUK%0'  ' DKK_g%0')  (' CHUK%0'  ' MYC%0')  (' CHUK%0'  ' CCND1%0')  (' CHUK%0'  ' EGR1%0')  (' CHUK%0'  ' MMP_f%0')  (' CHUK%0'  ' PTEN_g%0')  (' CHUK%0'  ' RTPK_f%0')  (' CHUK%0'  ' CTNNB1%0')  (' CHUK%0'  'LEF1%0')  (' CHUK%0'  'SFRP1%0')  (' CHUK%0'  'FZD_f%0')  (' CHUK%0'  ' CASP8%0')  (' CHUK%0'  ' REL_f%0')  (' CHUK%0'  ' NFKB_f%0')  (' CHUK%0'  ' DVL_f%0')  (' CHUK%0'  ' LRP_f%0')  (' CHUK%0'  ' BTRC%0')  (' CHUK%0'  ' CK1_f%0')  (' CHUK%0'  ' AXIN1%0')  (' CHUK%0'  ' mTORC2_c%0')  (' CHUK%0'  ' PDPK1%0')  (' CHUK%0'  ' MEK_f%0')  (' CHUK%0'  ' CYCS%0')  (' CHUK%0'  ' CASP9%0')  (' CHUK%0'  ' GSK3_f%0')  (' CHUK%0'  ' IRS1%0')  (' CHUK%0'  ' MDM2%0')  (' CHUK%0'  ' AKT_f%0')  (' CHUK%0'  ' BCL2%0')  (' CHUK%0'  ' RAF_f%0')  (' CHUK%0'  ' mTORC1_c%0')  (' CHUK%0'  ' RHEB%0')  (' CHUK%0'  ' RTPK_g%0')  (' CHUK%0'  ' PTEN%0')  (' CHUK%0'  ' CASP3%0')  (' CHUK%0'  ' PIK3CA%0')  (' CHUK%0'  ' CREBBP%0')  (' CHUK%0'  ' PTPN11%0')  (' CHUK%0'  ' KRAS%0')  (' CHUK%0'  ' MAP2K4%0')  (' CHUK%0'  ' MAP2K7%0')  (' CHUK%0'  ' MAPK14%0')  (' CHUK%0'  ' JNK_f%0')  (' CHUK%0'  ' MAP2K3%0')  (' CHUK%0'  ' ERK_f%0')  (' CHUK%0'  ' LIF%0')  (' CHUK%0'  ' PPP1CA%0')  (' CHUK%0'  ' GAB_f%0')  (' CHUK%0'  ' SOS1%0')  (' CHUK%0'  ' PRKCA%0')  (' CHUK%0'  ' VAV1%0')  (' CHUK%0'  ' PLCG1%0')  (' CHUK%0'  ' PRKCD%0')  (' CHUK%0'  ' RSK_f%0')  (' CHUK%0'  ' S6K_f%0')  (' CHUK%0'  ' PLK1%0')  (' CHUK%0'  ' ILK%0')  (' CHUK%0'  ' SOCS1%0')  (' CHUK%0'  ' DUSP6%0')  (' CHUK%0'  ' STAT3%0')  (' CHUK%0'  ' LIMK2%0')  (' CHUK%0'  ' EP300%0')  (' CHUK%0'  ' STAT1%0')  (' CHUK%0'  ' IKBKB%0')  (' CHUK%0'  ' SRF%0')  (' CHUK%0'  ' PIAS1%0')  (' CHUK%0'  ' TRAF6%0')  (' CHUK%0'  ' SOCS1_g%0')  (' CHUK%0'  ' ISGF3_c%0')  (' CHUK%0'  ' STAT2%0')  (' CHUK%0'  ' CFLAR%0')  (' CHUK%0'  ' SMAD2%0')  (' CHUK%0'  ' MDM2_g%0')  (' CHUK%0'  ' BAX%0')  (' CHUK%0'  ' PRKACA%0')  (' CHUK%0'  ' TGFB1%0')  (' CHUK%0'  ' MAP3K8%0')  (' CHUK%0'  ' TSC_f%0')  (' CHUK%0'  ' SMAD4%0')  (' CHUK%0'  ' BAD%0')  (' CHUK%0'  ' MAP3K5%0')  (' CHUK%0'  ' AKT1S1%0')  (' CHUK%0'  ' SKI%0')  (' CHUK%0'  ' SMAD3%0')  (' CHUK%0'  ' MAPKAPK2%0')  (' CHUK%0'  ' DUSP1_g%0')  (' CHUK%0'  ' MSK_f%0')  (' CHUK%0'  ' GRAP2%0')  (' CHUK%0'  ' TAB_f%0')  (' CHUK%0'  ' ATF2%0')  (' CHUK%0'  ' SMAD5%0')  (' CHUK%0'  ' SMAD1%0')  (' CHUK%0'  ' FOS%0')  (' CHUK%0'  ' JUN%0')  (' CHUK%0'  ' MAP3K7%0')  (' CHUK%0'  ' NLK%0')  (' CHUK%0'  ' SMAD7_g%0')  (' CHUK%0'  ' SMAD6_g%0')  (' CHUK%0'  ' AP1_c%0')  (' CHUK%0'  ' ACVR1%0')  (' CHUK%0'  ' PTPN6%0')  (' CHUK%0'  ' CDC42%0')  (' CHUK%0'  ' GRB2%0')  (' CHUK%0'  ' TGFBR1%0')  (' CHUK%0'  ' SMURF1%0')  (' CHUK%0'  ' SMURF2%0')  (' CHUK%0'  ' RHOA%0')  (' CHUK%0'  ' BMPR2%0')  (' CHUK%0'  ' PARD6A%0')  (' CHUK%0'  ' DAAM1%0')  (' CHUK%0'  ' SFRP1_g%0')  (' CHUK%0'  ' PPM1A%0')  (' CHUK%0'  ' CFL_f%0')  (' CHUK%0'  ' PAK1%0')  (' CHUK%0'  ' MAP3K11%0')  (' CHUK%0'  ' MAP3K4%0')  (' CHUK%0'  ' LIMK1%0')  (' CHUK%0'  ' ROCK1%0')  (' CHUK%0'  ' ITCH%0')  (' CHUK%0'  ' ARHGAP24%0')  (' CHUK%0'  ' TIAM1%0')  (' CHUK%0'  ' RND3%0')  (' CHUK%0'  ' MAPK8IP3%0')  (' CHUK%0'  ' MXD1%0')  (' CHUK%0'  ' PIP3%0')  (' RAC_f%0'  ' SRC%0')  (' RAC_f%0'  ' CSK%0')  (' RAC_f%0'  ' CHUK%0')  (' RAC_f%0'  ' DUSP1%0')  (' RAC_f%0'  ' TGFBR2%0')  (' RAC_f%0'  ' ILR_f%0')  (' RAC_f%0'  ' SYK%0')  (' RAC_f%0'  ' IRAK1%0')  (' RAC_f%0'  ' SHC1%0')  (' RAC_f%0'  ' JAK_f%0')  (' RAC_f%0'  ' CBPp300_c%0')  (' RAC_f%0'  ' SKP2%0')  (' RAC_f%0'  ' TP53%0')  (' RAC_f%0'  ' SMAD7%0')  (' RAC_f%0'  ' SMAD6%0')  (' RAC_f%0'  ' DKK_f%0')  (' RAC_f%0'  ' FOXO_f%0')  (' RAC_f%0'  ' TCF7_f%0')  (' RAC_f%0'  ' DKK_g%0')  (' RAC_f%0'  ' MYC%0')  (' RAC_f%0'  ' CCND1%0')  (' RAC_f%0'  ' EGR1%0')  (' RAC_f%0'  ' MMP_f%0')  (' RAC_f%0'  ' PTEN_g%0')  (' RAC_f%0'  ' RTPK_f%0')  (' RAC_f%0'  ' CTNNB1%0')  (' RAC_f%0'  'LEF1%0')  (' RAC_f%0'  'SFRP1%0')  (' RAC_f%0'  'FZD_f%0')  (' RAC_f%0'  ' CASP8%0')  (' RAC_f%0'  ' REL_f%0')  (' RAC_f%0'  ' NFKB_f%0')  (' RAC_f%0'  ' DVL_f%0')  (' RAC_f%0'  ' LRP_f%0')  (' RAC_f%0'  ' BTRC%0')  (' RAC_f%0'  ' CK1_f%0')  (' RAC_f%0'  ' AXIN1%0')  (' RAC_f%0'  ' mTORC2_c%0')  (' RAC_f%0'  ' PDPK1%0')  (' RAC_f%0'  ' MEK_f%0')  (' RAC_f%0'  ' CYCS%0')  (' RAC_f%0'  ' CASP9%0')  (' RAC_f%0'  ' GSK3_f%0')  (' RAC_f%0'  ' IRS1%0')  (' RAC_f%0'  ' MDM2%0')  (' RAC_f%0'  ' AKT_f%0')  (' RAC_f%0'  ' BCL2%0')  (' RAC_f%0'  ' RAF_f%0')  (' RAC_f%0'  ' mTORC1_c%0')  (' RAC_f%0'  ' RHEB%0')  (' RAC_f%0'  ' RTPK_g%0')  (' RAC_f%0'  ' PTEN%0')  (' RAC_f%0'  ' CASP3%0')  (' RAC_f%0'  ' PIK3CA%0')  (' RAC_f%0'  ' CREBBP%0')  (' RAC_f%0'  ' PTPN11%0')  (' RAC_f%0'  ' KRAS%0')  (' RAC_f%0'  ' MAP2K4%0')  (' RAC_f%0'  ' MAP2K7%0')  (' RAC_f%0'  ' MAPK14%0')  (' RAC_f%0'  ' JNK_f%0')  (' RAC_f%0'  ' MAP2K3%0')  (' RAC_f%0'  ' ERK_f%0')  (' RAC_f%0'  ' LIF%0')  (' RAC_f%0'  ' PPP1CA%0')  (' RAC_f%0'  ' GAB_f%0')  (' RAC_f%0'  ' SOS1%0')  (' RAC_f%0'  ' PRKCA%0')  (' RAC_f%0'  ' VAV1%0')  (' RAC_f%0'  ' PLCG1%0')  (' RAC_f%0'  ' PRKCD%0')  (' RAC_f%0'  ' RSK_f%0')  (' RAC_f%0'  ' S6K_f%0')  (' RAC_f%0'  ' PLK1%0')  (' RAC_f%0'  ' ILK%0')  (' RAC_f%0'  ' SOCS1%0')  (' RAC_f%0'  ' DUSP6%0')  (' RAC_f%0'  ' STAT3%0')  (' RAC_f%0'  ' LIMK2%0')  (' RAC_f%0'  ' EP300%0')  (' RAC_f%0'  ' STAT1%0')  (' RAC_f%0'  ' IKBKB%0')  (' RAC_f%0'  ' SRF%0')  (' RAC_f%0'  ' PIAS1%0')  (' RAC_f%0'  ' TRAF6%0')  (' RAC_f%0'  ' SOCS1_g%0')  (' RAC_f%0'  ' ISGF3_c%0')  (' RAC_f%0'  ' STAT2%0')  (' RAC_f%0'  ' CFLAR%0')  (' RAC_f%0'  ' SMAD2%0')  (' RAC_f%0'  ' MDM2_g%0')  (' RAC_f%0'  ' BAX%0')  (' RAC_f%0'  ' PRKACA%0')  (' RAC_f%0'  ' TGFB1%0')  (' RAC_f%0'  ' MAP3K8%0')  (' RAC_f%0'  ' TSC_f%0')  (' RAC_f%0'  ' SMAD4%0')  (' RAC_f%0'  ' BAD%0')  (' RAC_f%0'  ' MAP3K5%0')  (' RAC_f%0'  ' AKT1S1%0')  (' RAC_f%0'  ' SKI%0')  (' RAC_f%0'  ' SMAD3%0')  (' RAC_f%0'  ' MAPKAPK2%0')  (' RAC_f%0'  ' DUSP1_g%0')  (' RAC_f%0'  ' MSK_f%0')  (' RAC_f%0'  ' GRAP2%0')  (' RAC_f%0'  ' TAB_f%0')  (' RAC_f%0'  ' ATF2%0')  (' RAC_f%0'  ' SMAD5%0')  (' RAC_f%0'  ' SMAD1%0')  (' RAC_f%0'  ' FOS%0')  (' RAC_f%0'  ' JUN%0')  (' RAC_f%0'  ' MAP3K7%0')  (' RAC_f%0'  ' NLK%0')  (' RAC_f%0'  ' SMAD7_g%0')  (' RAC_f%0'  ' SMAD6_g%0')  (' RAC_f%0'  ' AP1_c%0')  (' RAC_f%0'  ' ACVR1%0')  (' RAC_f%0'  ' PTPN6%0')  (' RAC_f%0'  ' CDC42%0')  (' RAC_f%0'  ' GRB2%0')  (' RAC_f%0'  ' TGFBR1%0')  (' RAC_f%0'  ' SMURF1%0')  (' RAC_f%0'  ' SMURF2%0')  (' RAC_f%0'  ' RHOA%0')  (' RAC_f%0'  ' BMPR2%0')  (' RAC_f%0'  ' PARD6A%0')  (' RAC_f%0'  ' DAAM1%0')  (' RAC_f%0'  ' SFRP1_g%0')  (' RAC_f%0'  ' PPM1A%0')  (' RAC_f%0'  ' CFL_f%0')  (' RAC_f%0'  ' PAK1%0')  (' RAC_f%0'  ' MAP3K11%0')  (' RAC_f%0'  ' MAP3K4%0')  (' RAC_f%0'  ' LIMK1%0')  (' RAC_f%0'  ' ROCK1%0')  (' RAC_f%0'  ' ITCH%0')  (' RAC_f%0'  ' ARHGAP24%0')  (' RAC_f%0'  ' TIAM1%0')  (' RAC_f%0'  ' RND3%0')  (' RAC_f%0'  ' MAPK8IP3%0')  (' RAC_f%0'  ' MXD1%0')  (' RAC_f%0'  ' PIP3%0')  (' DUSP1%0'  ' SRC%0')  (' DUSP1%0'  ' CSK%0')  (' DUSP1%0'  ' CHUK%0')  (' DUSP1%0'  ' RAC_f%0')  (' DUSP1%0'  ' TGFBR2%0')  (' DUSP1%0'  ' ILR_f%0')  (' DUSP1%0'  ' SYK%0')  (' DUSP1%0'  ' IRAK1%0')  (' DUSP1%0'  ' SHC1%0')  (' DUSP1%0'  ' JAK_f%0')  (' DUSP1%0'  ' CBPp300_c%0')  (' DUSP1%0'  ' SKP2%0')  (' DUSP1%0'  ' TP53%0')  (' DUSP1%0'  ' SMAD7%0')  (' DUSP1%0'  ' SMAD6%0')  (' DUSP1%0'  ' DKK_f%0')  (' DUSP1%0'  ' FOXO_f%0')  (' DUSP1%0'  ' TCF7_f%0')  (' DUSP1%0'  ' DKK_g%0')  (' DUSP1%0'  ' MYC%0')  (' DUSP1%0'  ' CCND1%0')  (' DUSP1%0'  ' EGR1%0')  (' DUSP1%0'  ' MMP_f%0')  (' DUSP1%0'  ' PTEN_g%0')  (' DUSP1%0'  ' RTPK_f%0')  (' DUSP1%0'  ' CTNNB1%0')  (' DUSP1%0'  'LEF1%0')  (' DUSP1%0'  'SFRP1%0')  (' DUSP1%0'  'FZD_f%0')  (' DUSP1%0'  ' CASP8%0')  (' DUSP1%0'  ' REL_f%0')  (' DUSP1%0'  ' NFKB_f%0')  (' DUSP1%0'  ' DVL_f%0')  (' DUSP1%0'  ' LRP_f%0')  (' DUSP1%0'  ' BTRC%0')  (' DUSP1%0'  ' CK1_f%0')  (' DUSP1%0'  ' AXIN1%0')  (' DUSP1%0'  ' mTORC2_c%0')  (' DUSP1%0'  ' PDPK1%0')  (' DUSP1%0'  ' MEK_f%0')  (' DUSP1%0'  ' CYCS%0')  (' DUSP1%0'  ' CASP9%0')  (' DUSP1%0'  ' GSK3_f%0')  (' DUSP1%0'  ' IRS1%0')  (' DUSP1%0'  ' MDM2%0')  (' DUSP1%0'  ' AKT_f%0')  (' DUSP1%0'  ' BCL2%0')  (' DUSP1%0'  ' RAF_f%0')  (' DUSP1%0'  ' mTORC1_c%0')  (' DUSP1%0'  ' RHEB%0')  (' DUSP1%0'  ' RTPK_g%0')  (' DUSP1%0'  ' PTEN%0')  (' DUSP1%0'  ' CASP3%0')  (' DUSP1%0'  ' PIK3CA%0')  (' DUSP1%0'  ' CREBBP%0')  (' DUSP1%0'  ' PTPN11%0')  (' DUSP1%0'  ' KRAS%0')  (' DUSP1%0'  ' MAP2K4%0')  (' DUSP1%0'  ' MAP2K7%0')  (' DUSP1%0'  ' MAPK14%0')  (' DUSP1%0'  ' JNK_f%0')  (' DUSP1%0'  ' MAP2K3%0')  (' DUSP1%0'  ' ERK_f%0')  (' DUSP1%0'  ' LIF%0')  (' DUSP1%0'  ' PPP1CA%0')  (' DUSP1%0'  ' GAB_f%0')  (' DUSP1%0'  ' SOS1%0')  (' DUSP1%0'  ' PRKCA%0')  (' DUSP1%0'  ' VAV1%0')  (' DUSP1%0'  ' PLCG1%0')  (' DUSP1%0'  ' PRKCD%0')  (' DUSP1%0'  ' RSK_f%0')  (' DUSP1%0'  ' S6K_f%0')  (' DUSP1%0'  ' PLK1%0')  (' DUSP1%0'  ' ILK%0')  (' DUSP1%0'  ' SOCS1%0')  (' DUSP1%0'  ' DUSP6%0')  (' DUSP1%0'  ' STAT3%0')  (' DUSP1%0'  ' LIMK2%0')  (' DUSP1%0'  ' EP300%0')  (' DUSP1%0'  ' STAT1%0')  (' DUSP1%0'  ' IKBKB%0')  (' DUSP1%0'  ' SRF%0')  (' DUSP1%0'  ' PIAS1%0')  (' DUSP1%0'  ' TRAF6%0')  (' DUSP1%0'  ' SOCS1_g%0')  (' DUSP1%0'  ' ISGF3_c%0')  (' DUSP1%0'  ' STAT2%0')  (' DUSP1%0'  ' CFLAR%0')  (' DUSP1%0'  ' SMAD2%0')  (' DUSP1%0'  ' MDM2_g%0')  (' DUSP1%0'  ' BAX%0')  (' DUSP1%0'  ' PRKACA%0')  (' DUSP1%0'  ' TGFB1%0')  (' DUSP1%0'  ' MAP3K8%0')  (' DUSP1%0'  ' TSC_f%0')  (' DUSP1%0'  ' SMAD4%0')  (' DUSP1%0'  ' BAD%0')  (' DUSP1%0'  ' MAP3K5%0')  (' DUSP1%0'  ' AKT1S1%0')  (' DUSP1%0'  ' SKI%0')  (' DUSP1%0'  ' SMAD3%0')  (' DUSP1%0'  ' MAPKAPK2%0')  (' DUSP1%0'  ' DUSP1_g%0')  (' DUSP1%0'  ' MSK_f%0')  (' DUSP1%0'  ' GRAP2%0')  (' DUSP1%0'  ' TAB_f%0')  (' DUSP1%0'  ' ATF2%0')  (' DUSP1%0'  ' SMAD5%0')  (' DUSP1%0'  ' SMAD1%0')  (' DUSP1%0'  ' FOS%0')  (' DUSP1%0'  ' JUN%0')  (' DUSP1%0'  ' MAP3K7%0')  (' DUSP1%0'  ' NLK%0')  (' DUSP1%0'  ' SMAD7_g%0')  (' DUSP1%0'  ' SMAD6_g%0')  (' DUSP1%0'  ' AP1_c%0')  (' DUSP1%0'  ' ACVR1%0')  (' DUSP1%0'  ' PTPN6%0')  (' DUSP1%0'  ' CDC42%0')  (' DUSP1%0'  ' GRB2%0')  (' DUSP1%0'  ' TGFBR1%0')  (' DUSP1%0'  ' SMURF1%0')  (' DUSP1%0'  ' SMURF2%0')  (' DUSP1%0'  ' RHOA%0')  (' DUSP1%0'  ' BMPR2%0')  (' DUSP1%0'  ' PARD6A%0')  (' DUSP1%0'  ' DAAM1%0')  (' DUSP1%0'  ' SFRP1_g%0')  (' DUSP1%0'  ' PPM1A%0')  (' DUSP1%0'  ' CFL_f%0')  (' DUSP1%0'  ' PAK1%0')  (' DUSP1%0'  ' MAP3K11%0')  (' DUSP1%0'  ' MAP3K4%0')  (' DUSP1%0'  ' LIMK1%0')  (' DUSP1%0'  ' ROCK1%0')  (' DUSP1%0'  ' ITCH%0')  (' DUSP1%0'  ' ARHGAP24%0')  (' DUSP1%0'  ' TIAM1%0')  (' DUSP1%0'  ' RND3%0')  (' DUSP1%0'  ' MAPK8IP3%0')  (' DUSP1%0'  ' MXD1%0')  (' DUSP1%0'  ' PIP3%0')  (' TGFBR2%0'  ' SRC%0')  (' TGFBR2%0'  ' CSK%0')  (' TGFBR2%0'  ' CHUK%0')  (' TGFBR2%0'  ' RAC_f%0')  (' TGFBR2%0'  ' DUSP1%0')  (' TGFBR2%0'  ' ILR_f%0')  (' TGFBR2%0'  ' SYK%0')  (' TGFBR2%0'  ' IRAK1%0')  (' TGFBR2%0'  ' SHC1%0')  (' TGFBR2%0'  ' JAK_f%0')  (' TGFBR2%0'  ' CBPp300_c%0')  (' TGFBR2%0'  ' SKP2%0')  (' TGFBR2%0'  ' TP53%0')  (' TGFBR2%0'  ' SMAD7%0')  (' TGFBR2%0'  ' SMAD6%0')  (' TGFBR2%0'  ' DKK_f%0')  (' TGFBR2%0'  ' FOXO_f%0')  (' TGFBR2%0'  ' TCF7_f%0')  (' TGFBR2%0'  ' DKK_g%0')  (' TGFBR2%0'  ' MYC%0')  (' TGFBR2%0'  ' CCND1%0')  (' TGFBR2%0'  ' EGR1%0')  (' TGFBR2%0'  ' MMP_f%0')  (' TGFBR2%0'  ' PTEN_g%0')  (' TGFBR2%0'  ' RTPK_f%0')  (' TGFBR2%0'  ' CTNNB1%0')  (' TGFBR2%0'  'LEF1%0')  (' TGFBR2%0'  'SFRP1%0')  (' TGFBR2%0'  'FZD_f%0')  (' TGFBR2%0'  ' CASP8%0')  (' TGFBR2%0'  ' REL_f%0')  (' TGFBR2%0'  ' NFKB_f%0')  (' TGFBR2%0'  ' DVL_f%0')  (' TGFBR2%0'  ' LRP_f%0')  (' TGFBR2%0'  ' BTRC%0')  (' TGFBR2%0'  ' CK1_f%0')  (' TGFBR2%0'  ' AXIN1%0')  (' TGFBR2%0'  ' mTORC2_c%0')  (' TGFBR2%0'  ' PDPK1%0')  (' TGFBR2%0'  ' MEK_f%0')  (' TGFBR2%0'  ' CYCS%0')  (' TGFBR2%0'  ' CASP9%0')  (' TGFBR2%0'  ' GSK3_f%0')  (' TGFBR2%0'  ' IRS1%0')  (' TGFBR2%0'  ' MDM2%0')  (' TGFBR2%0'  ' AKT_f%0')  (' TGFBR2%0'  ' BCL2%0')  (' TGFBR2%0'  ' RAF_f%0')  (' TGFBR2%0'  ' mTORC1_c%0')  (' TGFBR2%0'  ' RHEB%0')  (' TGFBR2%0'  ' RTPK_g%0')  (' TGFBR2%0'  ' PTEN%0')  (' TGFBR2%0'  ' CASP3%0')  (' TGFBR2%0'  ' PIK3CA%0')  (' TGFBR2%0'  ' CREBBP%0')  (' TGFBR2%0'  ' PTPN11%0')  (' TGFBR2%0'  ' KRAS%0')  (' TGFBR2%0'  ' MAP2K4%0')  (' TGFBR2%0'  ' MAP2K7%0')  (' TGFBR2%0'  ' MAPK14%0')  (' TGFBR2%0'  ' JNK_f%0')  (' TGFBR2%0'  ' MAP2K3%0')  (' TGFBR2%0'  ' ERK_f%0')  (' TGFBR2%0'  ' LIF%0')  (' TGFBR2%0'  ' PPP1CA%0')  (' TGFBR2%0'  ' GAB_f%0')  (' TGFBR2%0'  ' SOS1%0')  (' TGFBR2%0'  ' PRKCA%0')  (' TGFBR2%0'  ' VAV1%0')  (' TGFBR2%0'  ' PLCG1%0')  (' TGFBR2%0'  ' PRKCD%0')  (' TGFBR2%0'  ' RSK_f%0')  (' TGFBR2%0'  ' S6K_f%0')  (' TGFBR2%0'  ' PLK1%0')  (' TGFBR2%0'  ' ILK%0')  (' TGFBR2%0'  ' SOCS1%0')  (' TGFBR2%0'  ' DUSP6%0')  (' TGFBR2%0'  ' STAT3%0')  (' TGFBR2%0'  ' LIMK2%0')  (' TGFBR2%0'  ' EP300%0')  (' TGFBR2%0'  ' STAT1%0')  (' TGFBR2%0'  ' IKBKB%0')  (' TGFBR2%0'  ' SRF%0')  (' TGFBR2%0'  ' PIAS1%0')  (' TGFBR2%0'  ' TRAF6%0')  (' TGFBR2%0'  ' SOCS1_g%0')  (' TGFBR2%0'  ' ISGF3_c%0')  (' TGFBR2%0'  ' STAT2%0')  (' TGFBR2%0'  ' CFLAR%0')  (' TGFBR2%0'  ' SMAD2%0')  (' TGFBR2%0'  ' MDM2_g%0')  (' TGFBR2%0'  ' BAX%0')  (' TGFBR2%0'  ' PRKACA%0')  (' TGFBR2%0'  ' TGFB1%0')  (' TGFBR2%0'  ' MAP3K8%0')  (' TGFBR2%0'  ' TSC_f%0')  (' TGFBR2%0'  ' SMAD4%0')  (' TGFBR2%0'  ' BAD%0')  (' TGFBR2%0'  ' MAP3K5%0')  (' TGFBR2%0'  ' AKT1S1%0')  (' TGFBR2%0'  ' SKI%0')  (' TGFBR2%0'  ' SMAD3%0')  (' TGFBR2%0'  ' MAPKAPK2%0')  (' TGFBR2%0'  ' DUSP1_g%0')  (' TGFBR2%0'  ' MSK_f%0')  (' TGFBR2%0'  ' GRAP2%0')  (' TGFBR2%0'  ' TAB_f%0')  (' TGFBR2%0'  ' ATF2%0')  (' TGFBR2%0'  ' SMAD5%0')  (' TGFBR2%0'  ' SMAD1%0')  (' TGFBR2%0'  ' FOS%0')  (' TGFBR2%0'  ' JUN%0')  (' TGFBR2%0'  ' MAP3K7%0')  (' TGFBR2%0'  ' NLK%0')  (' TGFBR2%0'  ' SMAD7_g%0')  (' TGFBR2%0'  ' SMAD6_g%0')  (' TGFBR2%0'  ' AP1_c%0')  (' TGFBR2%0'  ' ACVR1%0')  (' TGFBR2%0'  ' PTPN6%0')  (' TGFBR2%0'  ' CDC42%0')  (' TGFBR2%0'  ' GRB2%0')  (' TGFBR2%0'  ' TGFBR1%0')  (' TGFBR2%0'  ' SMURF1%0')  (' TGFBR2%0'  ' SMURF2%0')  (' TGFBR2%0'  ' RHOA%0')  (' TGFBR2%0'  ' BMPR2%0')  (' TGFBR2%0'  ' PARD6A%0')  (' TGFBR2%0'  ' DAAM1%0')  (' TGFBR2%0'  ' SFRP1_g%0')  (' TGFBR2%0'  ' PPM1A%0')  (' TGFBR2%0'  ' CFL_f%0')  (' TGFBR2%0'  ' PAK1%0')  (' TGFBR2%0'  ' MAP3K11%0')  (' TGFBR2%0'  ' MAP3K4%0')  (' TGFBR2%0'  ' LIMK1%0')  (' TGFBR2%0'  ' ROCK1%0')  (' TGFBR2%0'  ' ITCH%0')  (' TGFBR2%0'  ' ARHGAP24%0')  (' TGFBR2%0'  ' TIAM1%0')  (' TGFBR2%0'  ' RND3%0')  (' TGFBR2%0'  ' MAPK8IP3%0')  (' TGFBR2%0'  ' MXD1%0')  (' TGFBR2%0'  ' PIP3%0')  (' ILR_f%0'  ' SRC%0')  (' ILR_f%0'  ' CSK%0')  (' ILR_f%0'  ' CHUK%0')  (' ILR_f%0'  ' RAC_f%0')  (' ILR_f%0'  ' DUSP1%0')  (' ILR_f%0'  ' TGFBR2%0')  (' ILR_f%0'  ' SYK%0')  (' ILR_f%0'  ' IRAK1%0')  (' ILR_f%0'  ' SHC1%0')  (' ILR_f%0'  ' JAK_f%0')  (' ILR_f%0'  ' CBPp300_c%0')  (' ILR_f%0'  ' SKP2%0')  (' ILR_f%0'  ' TP53%0')  (' ILR_f%0'  ' SMAD7%0')  (' ILR_f%0'  ' SMAD6%0')  (' ILR_f%0'  ' DKK_f%0')  (' ILR_f%0'  ' FOXO_f%0')  (' ILR_f%0'  ' TCF7_f%0')  (' ILR_f%0'  ' DKK_g%0')  (' ILR_f%0'  ' MYC%0')  (' ILR_f%0'  ' CCND1%0')  (' ILR_f%0'  ' EGR1%0')  (' ILR_f%0'  ' MMP_f%0')  (' ILR_f%0'  ' PTEN_g%0')  (' ILR_f%0'  ' RTPK_f%0')  (' ILR_f%0'  ' CTNNB1%0')  (' ILR_f%0'  'LEF1%0')  (' ILR_f%0'  'SFRP1%0')  (' ILR_f%0'  'FZD_f%0')  (' ILR_f%0'  ' CASP8%0')  (' ILR_f%0'  ' REL_f%0')  (' ILR_f%0'  ' NFKB_f%0')  (' ILR_f%0'  ' DVL_f%0')  (' ILR_f%0'  ' LRP_f%0')  (' ILR_f%0'  ' BTRC%0')  (' ILR_f%0'  ' CK1_f%0')  (' ILR_f%0'  ' AXIN1%0')  (' ILR_f%0'  ' mTORC2_c%0')  (' ILR_f%0'  ' PDPK1%0')  (' ILR_f%0'  ' MEK_f%0')  (' ILR_f%0'  ' CYCS%0')  (' ILR_f%0'  ' CASP9%0')  (' ILR_f%0'  ' GSK3_f%0')  (' ILR_f%0'  ' IRS1%0')  (' ILR_f%0'  ' MDM2%0')  (' ILR_f%0'  ' AKT_f%0')  (' ILR_f%0'  ' BCL2%0')  (' ILR_f%0'  ' RAF_f%0')  (' ILR_f%0'  ' mTORC1_c%0')  (' ILR_f%0'  ' RHEB%0')  (' ILR_f%0'  ' RTPK_g%0')  (' ILR_f%0'  ' PTEN%0')  (' ILR_f%0'  ' CASP3%0')  (' ILR_f%0'  ' PIK3CA%0')  (' ILR_f%0'  ' CREBBP%0')  (' ILR_f%0'  ' PTPN11%0')  (' ILR_f%0'  ' KRAS%0')  (' ILR_f%0'  ' MAP2K4%0')  (' ILR_f%0'  ' MAP2K7%0')  (' ILR_f%0'  ' MAPK14%0')  (' ILR_f%0'  ' JNK_f%0')  (' ILR_f%0'  ' MAP2K3%0')  (' ILR_f%0'  ' ERK_f%0')  (' ILR_f%0'  ' LIF%0')  (' ILR_f%0'  ' PPP1CA%0')  (' ILR_f%0'  ' GAB_f%0')  (' ILR_f%0'  ' SOS1%0')  (' ILR_f%0'  ' PRKCA%0')  (' ILR_f%0'  ' VAV1%0')  (' ILR_f%0'  ' PLCG1%0')  (' ILR_f%0'  ' PRKCD%0')  (' ILR_f%0'  ' RSK_f%0')  (' ILR_f%0'  ' S6K_f%0')  (' ILR_f%0'  ' PLK1%0')  (' ILR_f%0'  ' ILK%0')  (' ILR_f%0'  ' SOCS1%0')  (' ILR_f%0'  ' DUSP6%0')  (' ILR_f%0'  ' STAT3%0')  (' ILR_f%0'  ' LIMK2%0')  (' ILR_f%0'  ' EP300%0')  (' ILR_f%0'  ' STAT1%0')  (' ILR_f%0'  ' IKBKB%0')  (' ILR_f%0'  ' SRF%0')  (' ILR_f%0'  ' PIAS1%0')  (' ILR_f%0'  ' TRAF6%0')  (' ILR_f%0'  ' SOCS1_g%0')  (' ILR_f%0'  ' ISGF3_c%0')  (' ILR_f%0'  ' STAT2%0')  (' ILR_f%0'  ' CFLAR%0')  (' ILR_f%0'  ' SMAD2%0')  (' ILR_f%0'  ' MDM2_g%0')  (' ILR_f%0'  ' BAX%0')  (' ILR_f%0'  ' PRKACA%0')  (' ILR_f%0'  ' TGFB1%0')  (' ILR_f%0'  ' MAP3K8%0')  (' ILR_f%0'  ' TSC_f%0')  (' ILR_f%0'  ' SMAD4%0')  (' ILR_f%0'  ' BAD%0')  (' ILR_f%0'  ' MAP3K5%0')  (' ILR_f%0'  ' AKT1S1%0')  (' ILR_f%0'  ' SKI%0')  (' ILR_f%0'  ' SMAD3%0')  (' ILR_f%0'  ' MAPKAPK2%0')  (' ILR_f%0'  ' DUSP1_g%0')  (' ILR_f%0'  ' MSK_f%0')  (' ILR_f%0'  ' GRAP2%0')  (' ILR_f%0'  ' TAB_f%0')  (' ILR_f%0'  ' ATF2%0')  (' ILR_f%0'  ' SMAD5%0')  (' ILR_f%0'  ' SMAD1%0')  (' ILR_f%0'  ' FOS%0')  (' ILR_f%0'  ' JUN%0')  (' ILR_f%0'  ' MAP3K7%0')  (' ILR_f%0'  ' NLK%0')  (' ILR_f%0'  ' SMAD7_g%0')  (' ILR_f%0'  ' SMAD6_g%0')  (' ILR_f%0'  ' AP1_c%0')  (' ILR_f%0'  ' ACVR1%0')  (' ILR_f%0'  ' PTPN6%0')  (' ILR_f%0'  ' CDC42%0')  (' ILR_f%0'  ' GRB2%0')  (' ILR_f%0'  ' TGFBR1%0')  (' ILR_f%0'  ' SMURF1%0')  (' ILR_f%0'  ' SMURF2%0')  (' ILR_f%0'  ' RHOA%0')  (' ILR_f%0'  ' BMPR2%0')  (' ILR_f%0'  ' PARD6A%0')  (' ILR_f%0'  ' DAAM1%0')  (' ILR_f%0'  ' SFRP1_g%0')  (' ILR_f%0'  ' PPM1A%0')  (' ILR_f%0'  ' CFL_f%0')  (' ILR_f%0'  ' PAK1%0')  (' ILR_f%0'  ' MAP3K11%0')  (' ILR_f%0'  ' MAP3K4%0')  (' ILR_f%0'  ' LIMK1%0')  (' ILR_f%0'  ' ROCK1%0')  (' ILR_f%0'  ' ITCH%0')  (' ILR_f%0'  ' ARHGAP24%0')  (' ILR_f%0'  ' TIAM1%0')  (' ILR_f%0'  ' RND3%0')  (' ILR_f%0'  ' MAPK8IP3%0')  (' ILR_f%0'  ' MXD1%0')  (' ILR_f%0'  ' PIP3%0')  (' SYK%0'  ' SRC%0')  (' SYK%0'  ' CSK%0')  (' SYK%0'  ' CHUK%0')  (' SYK%0'  ' RAC_f%0')  (' SYK%0'  ' DUSP1%0')  (' SYK%0'  ' TGFBR2%0')  (' SYK%0'  ' ILR_f%0')  (' SYK%0'  ' IRAK1%0')  (' SYK%0'  ' SHC1%0')  (' SYK%0'  ' JAK_f%0')  (' SYK%0'  ' CBPp300_c%0')  (' SYK%0'  ' SKP2%0')  (' SYK%0'  ' TP53%0')  (' SYK%0'  ' SMAD7%0')  (' SYK%0'  ' SMAD6%0')  (' SYK%0'  ' DKK_f%0')  (' SYK%0'  ' FOXO_f%0')  (' SYK%0'  ' TCF7_f%0')  (' SYK%0'  ' DKK_g%0')  (' SYK%0'  ' MYC%0')  (' SYK%0'  ' CCND1%0')  (' SYK%0'  ' EGR1%0')  (' SYK%0'  ' MMP_f%0')  (' SYK%0'  ' PTEN_g%0')  (' SYK%0'  ' RTPK_f%0')  (' SYK%0'  ' CTNNB1%0')  (' SYK%0'  'LEF1%0')  (' SYK%0'  'SFRP1%0')  (' SYK%0'  'FZD_f%0')  (' SYK%0'  ' CASP8%0')  (' SYK%0'  ' REL_f%0')  (' SYK%0'  ' NFKB_f%0')  (' SYK%0'  ' DVL_f%0')  (' SYK%0'  ' LRP_f%0')  (' SYK%0'  ' BTRC%0')  (' SYK%0'  ' CK1_f%0')  (' SYK%0'  ' AXIN1%0')  (' SYK%0'  ' mTORC2_c%0')  (' SYK%0'  ' PDPK1%0')  (' SYK%0'  ' MEK_f%0')  (' SYK%0'  ' CYCS%0')  (' SYK%0'  ' CASP9%0')  (' SYK%0'  ' GSK3_f%0')  (' SYK%0'  ' IRS1%0')  (' SYK%0'  ' MDM2%0')  (' SYK%0'  ' AKT_f%0')  (' SYK%0'  ' BCL2%0')  (' SYK%0'  ' RAF_f%0')  (' SYK%0'  ' mTORC1_c%0')  (' SYK%0'  ' RHEB%0')  (' SYK%0'  ' RTPK_g%0')  (' SYK%0'  ' PTEN%0')  (' SYK%0'  ' CASP3%0')  (' SYK%0'  ' PIK3CA%0')  (' SYK%0'  ' CREBBP%0')  (' SYK%0'  ' PTPN11%0')  (' SYK%0'  ' KRAS%0')  (' SYK%0'  ' MAP2K4%0')  (' SYK%0'  ' MAP2K7%0')  (' SYK%0'  ' MAPK14%0')  (' SYK%0'  ' JNK_f%0')  (' SYK%0'  ' MAP2K3%0')  (' SYK%0'  ' ERK_f%0')  (' SYK%0'  ' LIF%0')  (' SYK%0'  ' PPP1CA%0')  (' SYK%0'  ' GAB_f%0')  (' SYK%0'  ' SOS1%0')  (' SYK%0'  ' PRKCA%0')  (' SYK%0'  ' VAV1%0')  (' SYK%0'  ' PLCG1%0')  (' SYK%0'  ' PRKCD%0')  (' SYK%0'  ' RSK_f%0')  (' SYK%0'  ' S6K_f%0')  (' SYK%0'  ' PLK1%0')  (' SYK%0'  ' ILK%0')  (' SYK%0'  ' SOCS1%0')  (' SYK%0'  ' DUSP6%0')  (' SYK%0'  ' STAT3%0')  (' SYK%0'  ' LIMK2%0')  (' SYK%0'  ' EP300%0')  (' SYK%0'  ' STAT1%0')  (' SYK%0'  ' IKBKB%0')  (' SYK%0'  ' SRF%0')  (' SYK%0'  ' PIAS1%0')  (' SYK%0'  ' TRAF6%0')  (' SYK%0'  ' SOCS1_g%0')  (' SYK%0'  ' ISGF3_c%0')  (' SYK%0'  ' STAT2%0')  (' SYK%0'  ' CFLAR%0')  (' SYK%0'  ' SMAD2%0')  (' SYK%0'  ' MDM2_g%0')  (' SYK%0'  ' BAX%0')  (' SYK%0'  ' PRKACA%0')  (' SYK%0'  ' TGFB1%0')  (' SYK%0'  ' MAP3K8%0')  (' SYK%0'  ' TSC_f%0')  (' SYK%0'  ' SMAD4%0')  (' SYK%0'  ' BAD%0')  (' SYK%0'  ' MAP3K5%0')  (' SYK%0'  ' AKT1S1%0')  (' SYK%0'  ' SKI%0')  (' SYK%0'  ' SMAD3%0')  (' SYK%0'  ' MAPKAPK2%0')  (' SYK%0'  ' DUSP1_g%0')  (' SYK%0'  ' MSK_f%0')  (' SYK%0'  ' GRAP2%0')  (' SYK%0'  ' TAB_f%0')  (' SYK%0'  ' ATF2%0')  (' SYK%0'  ' SMAD5%0')  (' SYK%0'  ' SMAD1%0')  (' SYK%0'  ' FOS%0')  (' SYK%0'  ' JUN%0')  (' SYK%0'  ' MAP3K7%0')  (' SYK%0'  ' NLK%0')  (' SYK%0'  ' SMAD7_g%0')  (' SYK%0'  ' SMAD6_g%0')  (' SYK%0'  ' AP1_c%0')  (' SYK%0'  ' ACVR1%0')  (' SYK%0'  ' PTPN6%0')  (' SYK%0'  ' CDC42%0')  (' SYK%0'  ' GRB2%0')  (' SYK%0'  ' TGFBR1%0')  (' SYK%0'  ' SMURF1%0')  (' SYK%0'  ' SMURF2%0')  (' SYK%0'  ' RHOA%0')  (' SYK%0'  ' BMPR2%0')  (' SYK%0'  ' PARD6A%0')  (' SYK%0'  ' DAAM1%0')  (' SYK%0'  ' SFRP1_g%0')  (' SYK%0'  ' PPM1A%0')  (' SYK%0'  ' CFL_f%0')  (' SYK%0'  ' PAK1%0')  (' SYK%0'  ' MAP3K11%0')  (' SYK%0'  ' MAP3K4%0')  (' SYK%0'  ' LIMK1%0')  (' SYK%0'  ' ROCK1%0')  (' SYK%0'  ' ITCH%0')  (' SYK%0'  ' ARHGAP24%0')  (' SYK%0'  ' TIAM1%0')  (' SYK%0'  ' RND3%0')  (' SYK%0'  ' MAPK8IP3%0')  (' SYK%0'  ' MXD1%0')  (' SYK%0'  ' PIP3%0')  (' IRAK1%0'  ' SRC%0')  (' IRAK1%0'  ' CSK%0')  (' IRAK1%0'  ' CHUK%0')  (' IRAK1%0'  ' RAC_f%0')  (' IRAK1%0'  ' DUSP1%0')  (' IRAK1%0'  ' TGFBR2%0')  (' IRAK1%0'  ' ILR_f%0')  (' IRAK1%0'  ' SYK%0')  (' IRAK1%0'  ' SHC1%0')  (' IRAK1%0'  ' JAK_f%0')  (' IRAK1%0'  ' CBPp300_c%0')  (' IRAK1%0'  ' SKP2%0')  (' IRAK1%0'  ' TP53%0')  (' IRAK1%0'  ' SMAD7%0')  (' IRAK1%0'  ' SMAD6%0')  (' IRAK1%0'  ' DKK_f%0')  (' IRAK1%0'  ' FOXO_f%0')  (' IRAK1%0'  ' TCF7_f%0')  (' IRAK1%0'  ' DKK_g%0')  (' IRAK1%0'  ' MYC%0')  (' IRAK1%0'  ' CCND1%0')  (' IRAK1%0'  ' EGR1%0')  (' IRAK1%0'  ' MMP_f%0')  (' IRAK1%0'  ' PTEN_g%0')  (' IRAK1%0'  ' RTPK_f%0')  (' IRAK1%0'  ' CTNNB1%0')  (' IRAK1%0'  'LEF1%0')  (' IRAK1%0'  'SFRP1%0')  (' IRAK1%0'  'FZD_f%0')  (' IRAK1%0'  ' CASP8%0')  (' IRAK1%0'  ' REL_f%0')  (' IRAK1%0'  ' NFKB_f%0')  (' IRAK1%0'  ' DVL_f%0')  (' IRAK1%0'  ' LRP_f%0')  (' IRAK1%0'  ' BTRC%0')  (' IRAK1%0'  ' CK1_f%0')  (' IRAK1%0'  ' AXIN1%0')  (' IRAK1%0'  ' mTORC2_c%0')  (' IRAK1%0'  ' PDPK1%0')  (' IRAK1%0'  ' MEK_f%0')  (' IRAK1%0'  ' CYCS%0')  (' IRAK1%0'  ' CASP9%0')  (' IRAK1%0'  ' GSK3_f%0')  (' IRAK1%0'  ' IRS1%0')  (' IRAK1%0'  ' MDM2%0')  (' IRAK1%0'  ' AKT_f%0')  (' IRAK1%0'  ' BCL2%0')  (' IRAK1%0'  ' RAF_f%0')  (' IRAK1%0'  ' mTORC1_c%0')  (' IRAK1%0'  ' RHEB%0')  (' IRAK1%0'  ' RTPK_g%0')  (' IRAK1%0'  ' PTEN%0')  (' IRAK1%0'  ' CASP3%0')  (' IRAK1%0'  ' PIK3CA%0')  (' IRAK1%0'  ' CREBBP%0')  (' IRAK1%0'  ' PTPN11%0')  (' IRAK1%0'  ' KRAS%0')  (' IRAK1%0'  ' MAP2K4%0')  (' IRAK1%0'  ' MAP2K7%0')  (' IRAK1%0'  ' MAPK14%0')  (' IRAK1%0'  ' JNK_f%0')  (' IRAK1%0'  ' MAP2K3%0')  (' IRAK1%0'  ' ERK_f%0')  (' IRAK1%0'  ' LIF%0')  (' IRAK1%0'  ' PPP1CA%0')  (' IRAK1%0'  ' GAB_f%0')  (' IRAK1%0'  ' SOS1%0')  (' IRAK1%0'  ' PRKCA%0')  (' IRAK1%0'  ' VAV1%0')  (' IRAK1%0'  ' PLCG1%0')  (' IRAK1%0'  ' PRKCD%0')  (' IRAK1%0'  ' RSK_f%0')  (' IRAK1%0'  ' S6K_f%0')  (' IRAK1%0'  ' PLK1%0')  (' IRAK1%0'  ' ILK%0')  (' IRAK1%0'  ' SOCS1%0')  (' IRAK1%0'  ' DUSP6%0')  (' IRAK1%0'  ' STAT3%0')  (' IRAK1%0'  ' LIMK2%0')  (' IRAK1%0'  ' EP300%0')  (' IRAK1%0'  ' STAT1%0')  (' IRAK1%0'  ' IKBKB%0')  (' IRAK1%0'  ' SRF%0')  (' IRAK1%0'  ' PIAS1%0')  (' IRAK1%0'  ' TRAF6%0')  (' IRAK1%0'  ' SOCS1_g%0')  (' IRAK1%0'  ' ISGF3_c%0')  (' IRAK1%0'  ' STAT2%0')  (' IRAK1%0'  ' CFLAR%0')  (' IRAK1%0'  ' SMAD2%0')  (' IRAK1%0'  ' MDM2_g%0')  (' IRAK1%0'  ' BAX%0')  (' IRAK1%0'  ' PRKACA%0')  (' IRAK1%0'  ' TGFB1%0')  (' IRAK1%0'  ' MAP3K8%0')  (' IRAK1%0'  ' TSC_f%0')  (' IRAK1%0'  ' SMAD4%0')  (' IRAK1%0'  ' BAD%0')  (' IRAK1%0'  ' MAP3K5%0')  (' IRAK1%0'  ' AKT1S1%0')  (' IRAK1%0'  ' SKI%0')  (' IRAK1%0'  ' SMAD3%0')  (' IRAK1%0'  ' MAPKAPK2%0')  (' IRAK1%0'  ' DUSP1_g%0')  (' IRAK1%0'  ' MSK_f%0')  (' IRAK1%0'  ' GRAP2%0')  (' IRAK1%0'  ' TAB_f%0')  (' IRAK1%0'  ' ATF2%0')  (' IRAK1%0'  ' SMAD5%0')  (' IRAK1%0'  ' SMAD1%0')  (' IRAK1%0'  ' FOS%0')  (' IRAK1%0'  ' JUN%0')  (' IRAK1%0'  ' MAP3K7%0')  (' IRAK1%0'  ' NLK%0')  (' IRAK1%0'  ' SMAD7_g%0')  (' IRAK1%0'  ' SMAD6_g%0')  (' IRAK1%0'  ' AP1_c%0')  (' IRAK1%0'  ' ACVR1%0')  (' IRAK1%0'  ' PTPN6%0')  (' IRAK1%0'  ' CDC42%0')  (' IRAK1%0'  ' GRB2%0')  (' IRAK1%0'  ' TGFBR1%0')  (' IRAK1%0'  ' SMURF1%0')  (' IRAK1%0'  ' SMURF2%0')  (' IRAK1%0'  ' RHOA%0')  (' IRAK1%0'  ' BMPR2%0')  (' IRAK1%0'  ' PARD6A%0')  (' IRAK1%0'  ' DAAM1%0')  (' IRAK1%0'  ' SFRP1_g%0')  (' IRAK1%0'  ' PPM1A%0')  (' IRAK1%0'  ' CFL_f%0')  (' IRAK1%0'  ' PAK1%0')  (' IRAK1%0'  ' MAP3K11%0')  (' IRAK1%0'  ' MAP3K4%0')  (' IRAK1%0'  ' LIMK1%0')  (' IRAK1%0'  ' ROCK1%0')  (' IRAK1%0'  ' ITCH%0')  (' IRAK1%0'  ' ARHGAP24%0')  (' IRAK1%0'  ' TIAM1%0')  (' IRAK1%0'  ' RND3%0')  (' IRAK1%0'  ' MAPK8IP3%0')  (' IRAK1%0'  ' MXD1%0')  (' IRAK1%0'  ' PIP3%0')  (' SHC1%0'  ' SRC%0')  (' SHC1%0'  ' CSK%0')  (' SHC1%0'  ' CHUK%0')  (' SHC1%0'  ' RAC_f%0')  (' SHC1%0'  ' DUSP1%0')  (' SHC1%0'  ' TGFBR2%0')  (' SHC1%0'  ' ILR_f%0')  (' SHC1%0'  ' SYK%0')  (' SHC1%0'  ' IRAK1%0')  (' SHC1%0'  ' JAK_f%0')  (' SHC1%0'  ' CBPp300_c%0')  (' SHC1%0'  ' SKP2%0')  (' SHC1%0'  ' TP53%0')  (' SHC1%0'  ' SMAD7%0')  (' SHC1%0'  ' SMAD6%0')  (' SHC1%0'  ' DKK_f%0')  (' SHC1%0'  ' FOXO_f%0')  (' SHC1%0'  ' TCF7_f%0')  (' SHC1%0'  ' DKK_g%0')  (' SHC1%0'  ' MYC%0')  (' SHC1%0'  ' CCND1%0')  (' SHC1%0'  ' EGR1%0')  (' SHC1%0'  ' MMP_f%0')  (' SHC1%0'  ' PTEN_g%0')  (' SHC1%0'  ' RTPK_f%0')  (' SHC1%0'  ' CTNNB1%0')  (' SHC1%0'  'LEF1%0')  (' SHC1%0'  'SFRP1%0')  (' SHC1%0'  'FZD_f%0')  (' SHC1%0'  ' CASP8%0')  (' SHC1%0'  ' REL_f%0')  (' SHC1%0'  ' NFKB_f%0')  (' SHC1%0'  ' DVL_f%0')  (' SHC1%0'  ' LRP_f%0')  (' SHC1%0'  ' BTRC%0')  (' SHC1%0'  ' CK1_f%0')  (' SHC1%0'  ' AXIN1%0')  (' SHC1%0'  ' mTORC2_c%0')  (' SHC1%0'  ' PDPK1%0')  (' SHC1%0'  ' MEK_f%0')  (' SHC1%0'  ' CYCS%0')  (' SHC1%0'  ' CASP9%0')  (' SHC1%0'  ' GSK3_f%0')  (' SHC1%0'  ' IRS1%0')  (' SHC1%0'  ' MDM2%0')  (' SHC1%0'  ' AKT_f%0')  (' SHC1%0'  ' BCL2%0')  (' SHC1%0'  ' RAF_f%0')  (' SHC1%0'  ' mTORC1_c%0')  (' SHC1%0'  ' RHEB%0')  (' SHC1%0'  ' RTPK_g%0')  (' SHC1%0'  ' PTEN%0')  (' SHC1%0'  ' CASP3%0')  (' SHC1%0'  ' PIK3CA%0')  (' SHC1%0'  ' CREBBP%0')  (' SHC1%0'  ' PTPN11%0')  (' SHC1%0'  ' KRAS%0')  (' SHC1%0'  ' MAP2K4%0')  (' SHC1%0'  ' MAP2K7%0')  (' SHC1%0'  ' MAPK14%0')  (' SHC1%0'  ' JNK_f%0')  (' SHC1%0'  ' MAP2K3%0')  (' SHC1%0'  ' ERK_f%0')  (' SHC1%0'  ' LIF%0')  (' SHC1%0'  ' PPP1CA%0')  (' SHC1%0'  ' GAB_f%0')  (' SHC1%0'  ' SOS1%0')  (' SHC1%0'  ' PRKCA%0')  (' SHC1%0'  ' VAV1%0')  (' SHC1%0'  ' PLCG1%0')  (' SHC1%0'  ' PRKCD%0')  (' SHC1%0'  ' RSK_f%0')  (' SHC1%0'  ' S6K_f%0')  (' SHC1%0'  ' PLK1%0')  (' SHC1%0'  ' ILK%0')  (' SHC1%0'  ' SOCS1%0')  (' SHC1%0'  ' DUSP6%0')  (' SHC1%0'  ' STAT3%0')  (' SHC1%0'  ' LIMK2%0')  (' SHC1%0'  ' EP300%0')  (' SHC1%0'  ' STAT1%0')  (' SHC1%0'  ' IKBKB%0')  (' SHC1%0'  ' SRF%0')  (' SHC1%0'  ' PIAS1%0')  (' SHC1%0'  ' TRAF6%0')  (' SHC1%0'  ' SOCS1_g%0')  (' SHC1%0'  ' ISGF3_c%0')  (' SHC1%0'  ' STAT2%0')  (' SHC1%0'  ' CFLAR%0')  (' SHC1%0'  ' SMAD2%0')  (' SHC1%0'  ' MDM2_g%0')  (' SHC1%0'  ' BAX%0')  (' SHC1%0'  ' PRKACA%0')  (' SHC1%0'  ' TGFB1%0')  (' SHC1%0'  ' MAP3K8%0')  (' SHC1%0'  ' TSC_f%0')  (' SHC1%0'  ' SMAD4%0')  (' SHC1%0'  ' BAD%0')  (' SHC1%0'  ' MAP3K5%0')  (' SHC1%0'  ' AKT1S1%0')  (' SHC1%0'  ' SKI%0')  (' SHC1%0'  ' SMAD3%0')  (' SHC1%0'  ' MAPKAPK2%0')  (' SHC1%0'  ' DUSP1_g%0')  (' SHC1%0'  ' MSK_f%0')  (' SHC1%0'  ' GRAP2%0')  (' SHC1%0'  ' TAB_f%0')  (' SHC1%0'  ' ATF2%0')  (' SHC1%0'  ' SMAD5%0')  (' SHC1%0'  ' SMAD1%0')  (' SHC1%0'  ' FOS%0')  (' SHC1%0'  ' JUN%0')  (' SHC1%0'  ' MAP3K7%0')  (' SHC1%0'  ' NLK%0')  (' SHC1%0'  ' SMAD7_g%0')  (' SHC1%0'  ' SMAD6_g%0')  (' SHC1%0'  ' AP1_c%0')  (' SHC1%0'  ' ACVR1%0')  (' SHC1%0'  ' PTPN6%0')  (' SHC1%0'  ' CDC42%0')  (' SHC1%0'  ' GRB2%0')  (' SHC1%0'  ' TGFBR1%0')  (' SHC1%0'  ' SMURF1%0')  (' SHC1%0'  ' SMURF2%0')  (' SHC1%0'  ' RHOA%0')  (' SHC1%0'  ' BMPR2%0')  (' SHC1%0'  ' PARD6A%0')  (' SHC1%0'  ' DAAM1%0')  (' SHC1%0'  ' SFRP1_g%0')  (' SHC1%0'  ' PPM1A%0')  (' SHC1%0'  ' CFL_f%0')  (' SHC1%0'  ' PAK1%0')  (' SHC1%0'  ' MAP3K11%0')  (' SHC1%0'  ' MAP3K4%0')  (' SHC1%0'  ' LIMK1%0')  (' SHC1%0'  ' ROCK1%0')  (' SHC1%0'  ' ITCH%0')  (' SHC1%0'  ' ARHGAP24%0')  (' SHC1%0'  ' TIAM1%0')  (' SHC1%0'  ' RND3%0')  (' SHC1%0'  ' MAPK8IP3%0')  (' SHC1%0'  ' MXD1%0')  (' SHC1%0'  ' PIP3%0')  (' JAK_f%0'  ' SRC%0')  (' JAK_f%0'  ' CSK%0')  (' JAK_f%0'  ' CHUK%0')  (' JAK_f%0'  ' RAC_f%0')  (' JAK_f%0'  ' DUSP1%0')  (' JAK_f%0'  ' TGFBR2%0')  (' JAK_f%0'  ' ILR_f%0')  (' JAK_f%0'  ' SYK%0')  (' JAK_f%0'  ' IRAK1%0')  (' JAK_f%0'  ' SHC1%0')  (' JAK_f%0'  ' CBPp300_c%0')  (' JAK_f%0'  ' SKP2%0')  (' JAK_f%0'  ' TP53%0')  (' JAK_f%0'  ' SMAD7%0')  (' JAK_f%0'  ' SMAD6%0')  (' JAK_f%0'  ' DKK_f%0')  (' JAK_f%0'  ' FOXO_f%0')  (' JAK_f%0'  ' TCF7_f%0')  (' JAK_f%0'  ' DKK_g%0')  (' JAK_f%0'  ' MYC%0')  (' JAK_f%0'  ' CCND1%0')  (' JAK_f%0'  ' EGR1%0')  (' JAK_f%0'  ' MMP_f%0')  (' JAK_f%0'  ' PTEN_g%0')  (' JAK_f%0'  ' RTPK_f%0')  (' JAK_f%0'  ' CTNNB1%0')  (' JAK_f%0'  'LEF1%0')  (' JAK_f%0'  'SFRP1%0')  (' JAK_f%0'  'FZD_f%0')  (' JAK_f%0'  ' CASP8%0')  (' JAK_f%0'  ' REL_f%0')  (' JAK_f%0'  ' NFKB_f%0')  (' JAK_f%0'  ' DVL_f%0')  (' JAK_f%0'  ' LRP_f%0')  (' JAK_f%0'  ' BTRC%0')  (' JAK_f%0'  ' CK1_f%0')  (' JAK_f%0'  ' AXIN1%0')  (' JAK_f%0'  ' mTORC2_c%0')  (' JAK_f%0'  ' PDPK1%0')  (' JAK_f%0'  ' MEK_f%0')  (' JAK_f%0'  ' CYCS%0')  (' JAK_f%0'  ' CASP9%0')  (' JAK_f%0'  ' GSK3_f%0')  (' JAK_f%0'  ' IRS1%0')  (' JAK_f%0'  ' MDM2%0')  (' JAK_f%0'  ' AKT_f%0')  (' JAK_f%0'  ' BCL2%0')  (' JAK_f%0'  ' RAF_f%0')  (' JAK_f%0'  ' mTORC1_c%0')  (' JAK_f%0'  ' RHEB%0')  (' JAK_f%0'  ' RTPK_g%0')  (' JAK_f%0'  ' PTEN%0')  (' JAK_f%0'  ' CASP3%0')  (' JAK_f%0'  ' PIK3CA%0')  (' JAK_f%0'  ' CREBBP%0')  (' JAK_f%0'  ' PTPN11%0')  (' JAK_f%0'  ' KRAS%0')  (' JAK_f%0'  ' MAP2K4%0')  (' JAK_f%0'  ' MAP2K7%0')  (' JAK_f%0'  ' MAPK14%0')  (' JAK_f%0'  ' JNK_f%0')  (' JAK_f%0'  ' MAP2K3%0')  (' JAK_f%0'  ' ERK_f%0')  (' JAK_f%0'  ' LIF%0')  (' JAK_f%0'  ' PPP1CA%0')  (' JAK_f%0'  ' GAB_f%0')  (' JAK_f%0'  ' SOS1%0')  (' JAK_f%0'  ' PRKCA%0')  (' JAK_f%0'  ' VAV1%0')  (' JAK_f%0'  ' PLCG1%0')  (' JAK_f%0'  ' PRKCD%0')  (' JAK_f%0'  ' RSK_f%0')  (' JAK_f%0'  ' S6K_f%0')  (' JAK_f%0'  ' PLK1%0')  (' JAK_f%0'  ' ILK%0')  (' JAK_f%0'  ' SOCS1%0')  (' JAK_f%0'  ' DUSP6%0')  (' JAK_f%0'  ' STAT3%0')  (' JAK_f%0'  ' LIMK2%0')  (' JAK_f%0'  ' EP300%0')  (' JAK_f%0'  ' STAT1%0')  (' JAK_f%0'  ' IKBKB%0')  (' JAK_f%0'  ' SRF%0')  (' JAK_f%0'  ' PIAS1%0')  (' JAK_f%0'  ' TRAF6%0')  (' JAK_f%0'  ' SOCS1_g%0')  (' JAK_f%0'  ' ISGF3_c%0')  (' JAK_f%0'  ' STAT2%0')  (' JAK_f%0'  ' CFLAR%0')  (' JAK_f%0'  ' SMAD2%0')  (' JAK_f%0'  ' MDM2_g%0')  (' JAK_f%0'  ' BAX%0')  (' JAK_f%0'  ' PRKACA%0')  (' JAK_f%0'  ' TGFB1%0')  (' JAK_f%0'  ' MAP3K8%0')  (' JAK_f%0'  ' TSC_f%0')  (' JAK_f%0'  ' SMAD4%0')  (' JAK_f%0'  ' BAD%0')  (' JAK_f%0'  ' MAP3K5%0')  (' JAK_f%0'  ' AKT1S1%0')  (' JAK_f%0'  ' SKI%0')  (' JAK_f%0'  ' SMAD3%0')  (' JAK_f%0'  ' MAPKAPK2%0')  (' JAK_f%0'  ' DUSP1_g%0')  (' JAK_f%0'  ' MSK_f%0')  (' JAK_f%0'  ' GRAP2%0')  (' JAK_f%0'  ' TAB_f%0')  (' JAK_f%0'  ' ATF2%0')  (' JAK_f%0'  ' SMAD5%0')  (' JAK_f%0'  ' SMAD1%0')  (' JAK_f%0'  ' FOS%0')  (' JAK_f%0'  ' JUN%0')  (' JAK_f%0'  ' MAP3K7%0')  (' JAK_f%0'  ' NLK%0')  (' JAK_f%0'  ' SMAD7_g%0')  (' JAK_f%0'  ' SMAD6_g%0')  (' JAK_f%0'  ' AP1_c%0')  (' JAK_f%0'  ' ACVR1%0')  (' JAK_f%0'  ' PTPN6%0')  (' JAK_f%0'  ' CDC42%0')  (' JAK_f%0'  ' GRB2%0')  (' JAK_f%0'  ' TGFBR1%0')  (' JAK_f%0'  ' SMURF1%0')  (' JAK_f%0'  ' SMURF2%0')  (' JAK_f%0'  ' RHOA%0')  (' JAK_f%0'  ' BMPR2%0')  (' JAK_f%0'  ' PARD6A%0')  (' JAK_f%0'  ' DAAM1%0')  (' JAK_f%0'  ' SFRP1_g%0')  (' JAK_f%0'  ' PPM1A%0')  (' JAK_f%0'  ' CFL_f%0')  (' JAK_f%0'  ' PAK1%0')  (' JAK_f%0'  ' MAP3K11%0')  (' JAK_f%0'  ' MAP3K4%0')  (' JAK_f%0'  ' LIMK1%0')  (' JAK_f%0'  ' ROCK1%0')  (' JAK_f%0'  ' ITCH%0')  (' JAK_f%0'  ' ARHGAP24%0')  (' JAK_f%0'  ' TIAM1%0')  (' JAK_f%0'  ' RND3%0')  (' JAK_f%0'  ' MAPK8IP3%0')  (' JAK_f%0'  ' MXD1%0')  (' JAK_f%0'  ' PIP3%0')  (' CBPp300_c%0'  ' SRC%0')  (' CBPp300_c%0'  ' CSK%0')  (' CBPp300_c%0'  ' CHUK%0')  (' CBPp300_c%0'  ' RAC_f%0')  (' CBPp300_c%0'  ' DUSP1%0')  (' CBPp300_c%0'  ' TGFBR2%0')  (' CBPp300_c%0'  ' ILR_f%0')  (' CBPp300_c%0'  ' SYK%0')  (' CBPp300_c%0'  ' IRAK1%0')  (' CBPp300_c%0'  ' SHC1%0')  (' CBPp300_c%0'  ' JAK_f%0')  (' CBPp300_c%0'  ' SKP2%0')  (' CBPp300_c%0'  ' TP53%0')  (' CBPp300_c%0'  ' SMAD7%0')  (' CBPp300_c%0'  ' SMAD6%0')  (' CBPp300_c%0'  ' DKK_f%0')  (' CBPp300_c%0'  ' FOXO_f%0')  (' CBPp300_c%0'  ' TCF7_f%0')  (' CBPp300_c%0'  ' DKK_g%0')  (' CBPp300_c%0'  ' MYC%0')  (' CBPp300_c%0'  ' CCND1%0')  (' CBPp300_c%0'  ' EGR1%0')  (' CBPp300_c%0'  ' MMP_f%0')  (' CBPp300_c%0'  ' PTEN_g%0')  (' CBPp300_c%0'  ' RTPK_f%0')  (' CBPp300_c%0'  ' CTNNB1%0')  (' CBPp300_c%0'  'LEF1%0')  (' CBPp300_c%0'  'SFRP1%0')  (' CBPp300_c%0'  'FZD_f%0')  (' CBPp300_c%0'  ' CASP8%0')  (' CBPp300_c%0'  ' REL_f%0')  (' CBPp300_c%0'  ' NFKB_f%0')  (' CBPp300_c%0'  ' DVL_f%0')  (' CBPp300_c%0'  ' LRP_f%0')  (' CBPp300_c%0'  ' BTRC%0')  (' CBPp300_c%0'  ' CK1_f%0')  (' CBPp300_c%0'  ' AXIN1%0')  (' CBPp300_c%0'  ' mTORC2_c%0')  (' CBPp300_c%0'  ' PDPK1%0')  (' CBPp300_c%0'  ' MEK_f%0')  (' CBPp300_c%0'  ' CYCS%0')  (' CBPp300_c%0'  ' CASP9%0')  (' CBPp300_c%0'  ' GSK3_f%0')  (' CBPp300_c%0'  ' IRS1%0')  (' CBPp300_c%0'  ' MDM2%0')  (' CBPp300_c%0'  ' AKT_f%0')  (' CBPp300_c%0'  ' BCL2%0')  (' CBPp300_c%0'  ' RAF_f%0')  (' CBPp300_c%0'  ' mTORC1_c%0')  (' CBPp300_c%0'  ' RHEB%0')  (' CBPp300_c%0'  ' RTPK_g%0')  (' CBPp300_c%0'  ' PTEN%0')  (' CBPp300_c%0'  ' CASP3%0')  (' CBPp300_c%0'  ' PIK3CA%0')  (' CBPp300_c%0'  ' CREBBP%0')  (' CBPp300_c%0'  ' PTPN11%0')  (' CBPp300_c%0'  ' KRAS%0')  (' CBPp300_c%0'  ' MAP2K4%0')  (' CBPp300_c%0'  ' MAP2K7%0')  (' CBPp300_c%0'  ' MAPK14%0')  (' CBPp300_c%0'  ' JNK_f%0')  (' CBPp300_c%0'  ' MAP2K3%0')  (' CBPp300_c%0'  ' ERK_f%0')  (' CBPp300_c%0'  ' LIF%0')  (' CBPp300_c%0'  ' PPP1CA%0')  (' CBPp300_c%0'  ' GAB_f%0')  (' CBPp300_c%0'  ' SOS1%0')  (' CBPp300_c%0'  ' PRKCA%0')  (' CBPp300_c%0'  ' VAV1%0')  (' CBPp300_c%0'  ' PLCG1%0')  (' CBPp300_c%0'  ' PRKCD%0')  (' CBPp300_c%0'  ' RSK_f%0')  (' CBPp300_c%0'  ' S6K_f%0')  (' CBPp300_c%0'  ' PLK1%0')  (' CBPp300_c%0'  ' ILK%0')  (' CBPp300_c%0'  ' SOCS1%0')  (' CBPp300_c%0'  ' DUSP6%0')  (' CBPp300_c%0'  ' STAT3%0')  (' CBPp300_c%0'  ' LIMK2%0')  (' CBPp300_c%0'  ' EP300%0')  (' CBPp300_c%0'  ' STAT1%0')  (' CBPp300_c%0'  ' IKBKB%0')  (' CBPp300_c%0'  ' SRF%0')  (' CBPp300_c%0'  ' PIAS1%0')  (' CBPp300_c%0'  ' TRAF6%0')  (' CBPp300_c%0'  ' SOCS1_g%0')  (' CBPp300_c%0'  ' ISGF3_c%0')  (' CBPp300_c%0'  ' STAT2%0')  (' CBPp300_c%0'  ' CFLAR%0')  (' CBPp300_c%0'  ' SMAD2%0')  (' CBPp300_c%0'  ' MDM2_g%0')  (' CBPp300_c%0'  ' BAX%0')  (' CBPp300_c%0'  ' PRKACA%0')  (' CBPp300_c%0'  ' TGFB1%0')  (' CBPp300_c%0'  ' MAP3K8%0')  (' CBPp300_c%0'  ' TSC_f%0')  (' CBPp300_c%0'  ' SMAD4%0')  (' CBPp300_c%0'  ' BAD%0')  (' CBPp300_c%0'  ' MAP3K5%0')  (' CBPp300_c%0'  ' AKT1S1%0')  (' CBPp300_c%0'  ' SKI%0')  (' CBPp300_c%0'  ' SMAD3%0')  (' CBPp300_c%0'  ' MAPKAPK2%0')  (' CBPp300_c%0'  ' DUSP1_g%0')  (' CBPp300_c%0'  ' MSK_f%0')  (' CBPp300_c%0'  ' GRAP2%0')  (' CBPp300_c%0'  ' TAB_f%0')  (' CBPp300_c%0'  ' ATF2%0')  (' CBPp300_c%0'  ' SMAD5%0')  (' CBPp300_c%0'  ' SMAD1%0')  (' CBPp300_c%0'  ' FOS%0')  (' CBPp300_c%0'  ' JUN%0')  (' CBPp300_c%0'  ' MAP3K7%0')  (' CBPp300_c%0'  ' NLK%0')  (' CBPp300_c%0'  ' SMAD7_g%0')  (' CBPp300_c%0'  ' SMAD6_g%0')  (' CBPp300_c%0'  ' AP1_c%0')  (' CBPp300_c%0'  ' ACVR1%0')  (' CBPp300_c%0'  ' PTPN6%0')  (' CBPp300_c%0'  ' CDC42%0')  (' CBPp300_c%0'  ' GRB2%0')  (' CBPp300_c%0'  ' TGFBR1%0')  (' CBPp300_c%0'  ' SMURF1%0')  (' CBPp300_c%0'  ' SMURF2%0')  (' CBPp300_c%0'  ' RHOA%0')  (' CBPp300_c%0'  ' BMPR2%0')  (' CBPp300_c%0'  ' PARD6A%0')  (' CBPp300_c%0'  ' DAAM1%0')  (' CBPp300_c%0'  ' SFRP1_g%0')  (' CBPp300_c%0'  ' PPM1A%0')  (' CBPp300_c%0'  ' CFL_f%0')  (' CBPp300_c%0'  ' PAK1%0')  (' CBPp300_c%0'  ' MAP3K11%0')  (' CBPp300_c%0'  ' MAP3K4%0')  (' CBPp300_c%0'  ' LIMK1%0')  (' CBPp300_c%0'  ' ROCK1%0')  (' CBPp300_c%0'  ' ITCH%0')  (' CBPp300_c%0'  ' ARHGAP24%0')  (' CBPp300_c%0'  ' TIAM1%0')  (' CBPp300_c%0'  ' RND3%0')  (' CBPp300_c%0'  ' MAPK8IP3%0')  (' CBPp300_c%0'  ' MXD1%0')  (' CBPp300_c%0'  ' PIP3%0')  (' SKP2%0'  ' SRC%0')  (' SKP2%0'  ' CSK%0')  (' SKP2%0'  ' CHUK%0')  (' SKP2%0'  ' RAC_f%0')  (' SKP2%0'  ' DUSP1%0')  (' SKP2%0'  ' TGFBR2%0')  (' SKP2%0'  ' ILR_f%0')  (' SKP2%0'  ' SYK%0')  (' SKP2%0'  ' IRAK1%0')  (' SKP2%0'  ' SHC1%0')  (' SKP2%0'  ' JAK_f%0')  (' SKP2%0'  ' CBPp300_c%0')  (' SKP2%0'  ' TP53%0')  (' SKP2%0'  ' SMAD7%0')  (' SKP2%0'  ' SMAD6%0')  (' SKP2%0'  ' DKK_f%0')  (' SKP2%0'  ' FOXO_f%0')  (' SKP2%0'  ' TCF7_f%0')  (' SKP2%0'  ' DKK_g%0')  (' SKP2%0'  ' MYC%0')  (' SKP2%0'  ' CCND1%0')  (' SKP2%0'  ' EGR1%0')  (' SKP2%0'  ' MMP_f%0')  (' SKP2%0'  ' PTEN_g%0')  (' SKP2%0'  ' RTPK_f%0')  (' SKP2%0'  ' CTNNB1%0')  (' SKP2%0'  'LEF1%0')  (' SKP2%0'  'SFRP1%0')  (' SKP2%0'  'FZD_f%0')  (' SKP2%0'  ' CASP8%0')  (' SKP2%0'  ' REL_f%0')  (' SKP2%0'  ' NFKB_f%0')  (' SKP2%0'  ' DVL_f%0')  (' SKP2%0'  ' LRP_f%0')  (' SKP2%0'  ' BTRC%0')  (' SKP2%0'  ' CK1_f%0')  (' SKP2%0'  ' AXIN1%0')  (' SKP2%0'  ' mTORC2_c%0')  (' SKP2%0'  ' PDPK1%0')  (' SKP2%0'  ' MEK_f%0')  (' SKP2%0'  ' CYCS%0')  (' SKP2%0'  ' CASP9%0')  (' SKP2%0'  ' GSK3_f%0')  (' SKP2%0'  ' IRS1%0')  (' SKP2%0'  ' MDM2%0')  (' SKP2%0'  ' AKT_f%0')  (' SKP2%0'  ' BCL2%0')  (' SKP2%0'  ' RAF_f%0')  (' SKP2%0'  ' mTORC1_c%0')  (' SKP2%0'  ' RHEB%0')  (' SKP2%0'  ' RTPK_g%0')  (' SKP2%0'  ' PTEN%0')  (' SKP2%0'  ' CASP3%0')  (' SKP2%0'  ' PIK3CA%0')  (' SKP2%0'  ' CREBBP%0')  (' SKP2%0'  ' PTPN11%0')  (' SKP2%0'  ' KRAS%0')  (' SKP2%0'  ' MAP2K4%0')  (' SKP2%0'  ' MAP2K7%0')  (' SKP2%0'  ' MAPK14%0')  (' SKP2%0'  ' JNK_f%0')  (' SKP2%0'  ' MAP2K3%0')  (' SKP2%0'  ' ERK_f%0')  (' SKP2%0'  ' LIF%0')  (' SKP2%0'  ' PPP1CA%0')  (' SKP2%0'  ' GAB_f%0')  (' SKP2%0'  ' SOS1%0')  (' SKP2%0'  ' PRKCA%0')  (' SKP2%0'  ' VAV1%0')  (' SKP2%0'  ' PLCG1%0')  (' SKP2%0'  ' PRKCD%0')  (' SKP2%0'  ' RSK_f%0')  (' SKP2%0'  ' S6K_f%0')  (' SKP2%0'  ' PLK1%0')  (' SKP2%0'  ' ILK%0')  (' SKP2%0'  ' SOCS1%0')  (' SKP2%0'  ' DUSP6%0')  (' SKP2%0'  ' STAT3%0')  (' SKP2%0'  ' LIMK2%0')  (' SKP2%0'  ' EP300%0')  (' SKP2%0'  ' STAT1%0')  (' SKP2%0'  ' IKBKB%0')  (' SKP2%0'  ' SRF%0')  (' SKP2%0'  ' PIAS1%0')  (' SKP2%0'  ' TRAF6%0')  (' SKP2%0'  ' SOCS1_g%0')  (' SKP2%0'  ' ISGF3_c%0')  (' SKP2%0'  ' STAT2%0')  (' SKP2%0'  ' CFLAR%0')  (' SKP2%0'  ' SMAD2%0')  (' SKP2%0'  ' MDM2_g%0')  (' SKP2%0'  ' BAX%0')  (' SKP2%0'  ' PRKACA%0')  (' SKP2%0'  ' TGFB1%0')  (' SKP2%0'  ' MAP3K8%0')  (' SKP2%0'  ' TSC_f%0')  (' SKP2%0'  ' SMAD4%0')  (' SKP2%0'  ' BAD%0')  (' SKP2%0'  ' MAP3K5%0')  (' SKP2%0'  ' AKT1S1%0')  (' SKP2%0'  ' SKI%0')  (' SKP2%0'  ' SMAD3%0')  (' SKP2%0'  ' MAPKAPK2%0')  (' SKP2%0'  ' DUSP1_g%0')  (' SKP2%0'  ' MSK_f%0')  (' SKP2%0'  ' GRAP2%0')  (' SKP2%0'  ' TAB_f%0')  (' SKP2%0'  ' ATF2%0')  (' SKP2%0'  ' SMAD5%0')  (' SKP2%0'  ' SMAD1%0')  (' SKP2%0'  ' FOS%0')  (' SKP2%0'  ' JUN%0')  (' SKP2%0'  ' MAP3K7%0')  (' SKP2%0'  ' NLK%0')  (' SKP2%0'  ' SMAD7_g%0')  (' SKP2%0'  ' SMAD6_g%0')  (' SKP2%0'  ' AP1_c%0')  (' SKP2%0'  ' ACVR1%0')  (' SKP2%0'  ' PTPN6%0')  (' SKP2%0'  ' CDC42%0')  (' SKP2%0'  ' GRB2%0')  (' SKP2%0'  ' TGFBR1%0')  (' SKP2%0'  ' SMURF1%0')  (' SKP2%0'  ' SMURF2%0')  (' SKP2%0'  ' RHOA%0')  (' SKP2%0'  ' BMPR2%0')  (' SKP2%0'  ' PARD6A%0')  (' SKP2%0'  ' DAAM1%0')  (' SKP2%0'  ' SFRP1_g%0')  (' SKP2%0'  ' PPM1A%0')  (' SKP2%0'  ' CFL_f%0')  (' SKP2%0'  ' PAK1%0')  (' SKP2%0'  ' MAP3K11%0')  (' SKP2%0'  ' MAP3K4%0')  (' SKP2%0'  ' LIMK1%0')  (' SKP2%0'  ' ROCK1%0')  (' SKP2%0'  ' ITCH%0')  (' SKP2%0'  ' ARHGAP24%0')  (' SKP2%0'  ' TIAM1%0')  (' SKP2%0'  ' RND3%0')  (' SKP2%0'  ' MAPK8IP3%0')  (' SKP2%0'  ' MXD1%0')  (' SKP2%0'  ' PIP3%0')  (' TP53%0'  ' SRC%0')  (' TP53%0'  ' CSK%0')  (' TP53%0'  ' CHUK%0')  (' TP53%0'  ' RAC_f%0')  (' TP53%0'  ' DUSP1%0')  (' TP53%0'  ' TGFBR2%0')  (' TP53%0'  ' ILR_f%0')  (' TP53%0'  ' SYK%0')  (' TP53%0'  ' IRAK1%0')  (' TP53%0'  ' SHC1%0')  (' TP53%0'  ' JAK_f%0')  (' TP53%0'  ' CBPp300_c%0')  (' TP53%0'  ' SKP2%0')  (' TP53%0'  ' SMAD7%0')  (' TP53%0'  ' SMAD6%0')  (' TP53%0'  ' DKK_f%0')  (' TP53%0'  ' FOXO_f%0')  (' TP53%0'  ' TCF7_f%0')  (' TP53%0'  ' DKK_g%0')  (' TP53%0'  ' MYC%0')  (' TP53%0'  ' CCND1%0')  (' TP53%0'  ' EGR1%0')  (' TP53%0'  ' MMP_f%0')  (' TP53%0'  ' PTEN_g%0')  (' TP53%0'  ' RTPK_f%0')  (' TP53%0'  ' CTNNB1%0')  (' TP53%0'  'LEF1%0')  (' TP53%0'  'SFRP1%0')  (' TP53%0'  'FZD_f%0')  (' TP53%0'  ' CASP8%0')  (' TP53%0'  ' REL_f%0')  (' TP53%0'  ' NFKB_f%0')  (' TP53%0'  ' DVL_f%0')  (' TP53%0'  ' LRP_f%0')  (' TP53%0'  ' BTRC%0')  (' TP53%0'  ' CK1_f%0')  (' TP53%0'  ' AXIN1%0')  (' TP53%0'  ' mTORC2_c%0')  (' TP53%0'  ' PDPK1%0')  (' TP53%0'  ' MEK_f%0')  (' TP53%0'  ' CYCS%0')  (' TP53%0'  ' CASP9%0')  (' TP53%0'  ' GSK3_f%0')  (' TP53%0'  ' IRS1%0')  (' TP53%0'  ' MDM2%0')  (' TP53%0'  ' AKT_f%0')  (' TP53%0'  ' BCL2%0')  (' TP53%0'  ' RAF_f%0')  (' TP53%0'  ' mTORC1_c%0')  (' TP53%0'  ' RHEB%0')  (' TP53%0'  ' RTPK_g%0')  (' TP53%0'  ' PTEN%0')  (' TP53%0'  ' CASP3%0')  (' TP53%0'  ' PIK3CA%0')  (' TP53%0'  ' CREBBP%0')  (' TP53%0'  ' PTPN11%0')  (' TP53%0'  ' KRAS%0')  (' TP53%0'  ' MAP2K4%0')  (' TP53%0'  ' MAP2K7%0')  (' TP53%0'  ' MAPK14%0')  (' TP53%0'  ' JNK_f%0')  (' TP53%0'  ' MAP2K3%0')  (' TP53%0'  ' ERK_f%0')  (' TP53%0'  ' LIF%0')  (' TP53%0'  ' PPP1CA%0')  (' TP53%0'  ' GAB_f%0')  (' TP53%0'  ' SOS1%0')  (' TP53%0'  ' PRKCA%0')  (' TP53%0'  ' VAV1%0')  (' TP53%0'  ' PLCG1%0')  (' TP53%0'  ' PRKCD%0')  (' TP53%0'  ' RSK_f%0')  (' TP53%0'  ' S6K_f%0')  (' TP53%0'  ' PLK1%0')  (' TP53%0'  ' ILK%0')  (' TP53%0'  ' SOCS1%0')  (' TP53%0'  ' DUSP6%0')  (' TP53%0'  ' STAT3%0')  (' TP53%0'  ' LIMK2%0')  (' TP53%0'  ' EP300%0')  (' TP53%0'  ' STAT1%0')  (' TP53%0'  ' IKBKB%0')  (' TP53%0'  ' SRF%0')  (' TP53%0'  ' PIAS1%0')  (' TP53%0'  ' TRAF6%0')  (' TP53%0'  ' SOCS1_g%0')  (' TP53%0'  ' ISGF3_c%0')  (' TP53%0'  ' STAT2%0')  (' TP53%0'  ' CFLAR%0')  (' TP53%0'  ' SMAD2%0')  (' TP53%0'  ' MDM2_g%0')  (' TP53%0'  ' BAX%0')  (' TP53%0'  ' PRKACA%0')  (' TP53%0'  ' TGFB1%0')  (' TP53%0'  ' MAP3K8%0')  (' TP53%0'  ' TSC_f%0')  (' TP53%0'  ' SMAD4%0')  (' TP53%0'  ' BAD%0')  (' TP53%0'  ' MAP3K5%0')  (' TP53%0'  ' AKT1S1%0')  (' TP53%0'  ' SKI%0')  (' TP53%0'  ' SMAD3%0')  (' TP53%0'  ' MAPKAPK2%0')  (' TP53%0'  ' DUSP1_g%0')  (' TP53%0'  ' MSK_f%0')  (' TP53%0'  ' GRAP2%0')  (' TP53%0'  ' TAB_f%0')  (' TP53%0'  ' ATF2%0')  (' TP53%0'  ' SMAD5%0')  (' TP53%0'  ' SMAD1%0')  (' TP53%0'  ' FOS%0')  (' TP53%0'  ' JUN%0')  (' TP53%0'  ' MAP3K7%0')  (' TP53%0'  ' NLK%0')  (' TP53%0'  ' SMAD7_g%0')  (' TP53%0'  ' SMAD6_g%0')  (' TP53%0'  ' AP1_c%0')  (' TP53%0'  ' ACVR1%0')  (' TP53%0'  ' PTPN6%0')  (' TP53%0'  ' CDC42%0')  (' TP53%0'  ' GRB2%0')  (' TP53%0'  ' TGFBR1%0')  (' TP53%0'  ' SMURF1%0')  (' TP53%0'  ' SMURF2%0')  (' TP53%0'  ' RHOA%0')  (' TP53%0'  ' BMPR2%0')  (' TP53%0'  ' PARD6A%0')  (' TP53%0'  ' DAAM1%0')  (' TP53%0'  ' SFRP1_g%0')  (' TP53%0'  ' PPM1A%0')  (' TP53%0'  ' CFL_f%0')  (' TP53%0'  ' PAK1%0')  (' TP53%0'  ' MAP3K11%0')  (' TP53%0'  ' MAP3K4%0')  (' TP53%0'  ' LIMK1%0')  (' TP53%0'  ' ROCK1%0')  (' TP53%0'  ' ITCH%0')  (' TP53%0'  ' ARHGAP24%0')  (' TP53%0'  ' TIAM1%0')  (' TP53%0'  ' RND3%0')  (' TP53%0'  ' MAPK8IP3%0')  (' TP53%0'  ' MXD1%0')  (' TP53%0'  ' PIP3%0')  (' SMAD7%0'  ' SRC%0')  (' SMAD7%0'  ' CSK%0')  (' SMAD7%0'  ' CHUK%0')  (' SMAD7%0'  ' RAC_f%0')  (' SMAD7%0'  ' DUSP1%0')  (' SMAD7%0'  ' TGFBR2%0')  (' SMAD7%0'  ' ILR_f%0')  (' SMAD7%0'  ' SYK%0')  (' SMAD7%0'  ' IRAK1%0')  (' SMAD7%0'  ' SHC1%0')  (' SMAD7%0'  ' JAK_f%0')  (' SMAD7%0'  ' CBPp300_c%0')  (' SMAD7%0'  ' SKP2%0')  (' SMAD7%0'  ' TP53%0')  (' SMAD7%0'  ' SMAD6%0')  (' SMAD7%0'  ' DKK_f%0')  (' SMAD7%0'  ' FOXO_f%0')  (' SMAD7%0'  ' TCF7_f%0')  (' SMAD7%0'  ' DKK_g%0')  (' SMAD7%0'  ' MYC%0')  (' SMAD7%0'  ' CCND1%0')  (' SMAD7%0'  ' EGR1%0')  (' SMAD7%0'  ' MMP_f%0')  (' SMAD7%0'  ' PTEN_g%0')  (' SMAD7%0'  ' RTPK_f%0')  (' SMAD7%0'  ' CTNNB1%0')  (' SMAD7%0'  'LEF1%0')  (' SMAD7%0'  'SFRP1%0')  (' SMAD7%0'  'FZD_f%0')  (' SMAD7%0'  ' CASP8%0')  (' SMAD7%0'  ' REL_f%0')  (' SMAD7%0'  ' NFKB_f%0')  (' SMAD7%0'  ' DVL_f%0')  (' SMAD7%0'  ' LRP_f%0')  (' SMAD7%0'  ' BTRC%0')  (' SMAD7%0'  ' CK1_f%0')  (' SMAD7%0'  ' AXIN1%0')  (' SMAD7%0'  ' mTORC2_c%0')  (' SMAD7%0'  ' PDPK1%0')  (' SMAD7%0'  ' MEK_f%0')  (' SMAD7%0'  ' CYCS%0')  (' SMAD7%0'  ' CASP9%0')  (' SMAD7%0'  ' GSK3_f%0')  (' SMAD7%0'  ' IRS1%0')  (' SMAD7%0'  ' MDM2%0')  (' SMAD7%0'  ' AKT_f%0')  (' SMAD7%0'  ' BCL2%0')  (' SMAD7%0'  ' RAF_f%0')  (' SMAD7%0'  ' mTORC1_c%0')  (' SMAD7%0'  ' RHEB%0')  (' SMAD7%0'  ' RTPK_g%0')  (' SMAD7%0'  ' PTEN%0')  (' SMAD7%0'  ' CASP3%0')  (' SMAD7%0'  ' PIK3CA%0')  (' SMAD7%0'  ' CREBBP%0')  (' SMAD7%0'  ' PTPN11%0')  (' SMAD7%0'  ' KRAS%0')  (' SMAD7%0'  ' MAP2K4%0')  (' SMAD7%0'  ' MAP2K7%0')  (' SMAD7%0'  ' MAPK14%0')  (' SMAD7%0'  ' JNK_f%0')  (' SMAD7%0'  ' MAP2K3%0')  (' SMAD7%0'  ' ERK_f%0')  (' SMAD7%0'  ' LIF%0')  (' SMAD7%0'  ' PPP1CA%0')  (' SMAD7%0'  ' GAB_f%0')  (' SMAD7%0'  ' SOS1%0')  (' SMAD7%0'  ' PRKCA%0')  (' SMAD7%0'  ' VAV1%0')  (' SMAD7%0'  ' PLCG1%0')  (' SMAD7%0'  ' PRKCD%0')  (' SMAD7%0'  ' RSK_f%0')  (' SMAD7%0'  ' S6K_f%0')  (' SMAD7%0'  ' PLK1%0')  (' SMAD7%0'  ' ILK%0')  (' SMAD7%0'  ' SOCS1%0')  (' SMAD7%0'  ' DUSP6%0')  (' SMAD7%0'  ' STAT3%0')  (' SMAD7%0'  ' LIMK2%0')  (' SMAD7%0'  ' EP300%0')  (' SMAD7%0'  ' STAT1%0')  (' SMAD7%0'  ' IKBKB%0')  (' SMAD7%0'  ' SRF%0')  (' SMAD7%0'  ' PIAS1%0')  (' SMAD7%0'  ' TRAF6%0')  (' SMAD7%0'  ' SOCS1_g%0')  (' SMAD7%0'  ' ISGF3_c%0')  (' SMAD7%0'  ' STAT2%0')  (' SMAD7%0'  ' CFLAR%0')  (' SMAD7%0'  ' SMAD2%0')  (' SMAD7%0'  ' MDM2_g%0')  (' SMAD7%0'  ' BAX%0')  (' SMAD7%0'  ' PRKACA%0')  (' SMAD7%0'  ' TGFB1%0')  (' SMAD7%0'  ' MAP3K8%0')  (' SMAD7%0'  ' TSC_f%0')  (' SMAD7%0'  ' SMAD4%0')  (' SMAD7%0'  ' BAD%0')  (' SMAD7%0'  ' MAP3K5%0')  (' SMAD7%0'  ' AKT1S1%0')  (' SMAD7%0'  ' SKI%0')  (' SMAD7%0'  ' SMAD3%0')  (' SMAD7%0'  ' MAPKAPK2%0')  (' SMAD7%0'  ' DUSP1_g%0')  (' SMAD7%0'  ' MSK_f%0')  (' SMAD7%0'  ' GRAP2%0')  (' SMAD7%0'  ' TAB_f%0')  (' SMAD7%0'  ' ATF2%0')  (' SMAD7%0'  ' SMAD5%0')  (' SMAD7%0'  ' SMAD1%0')  (' SMAD7%0'  ' FOS%0')  (' SMAD7%0'  ' JUN%0')  (' SMAD7%0'  ' MAP3K7%0')  (' SMAD7%0'  ' NLK%0')  (' SMAD7%0'  ' SMAD7_g%0')  (' SMAD7%0'  ' SMAD6_g%0')  (' SMAD7%0'  ' AP1_c%0')  (' SMAD7%0'  ' ACVR1%0')  (' SMAD7%0'  ' PTPN6%0')  (' SMAD7%0'  ' CDC42%0')  (' SMAD7%0'  ' GRB2%0')  (' SMAD7%0'  ' TGFBR1%0')  (' SMAD7%0'  ' SMURF1%0')  (' SMAD7%0'  ' SMURF2%0')  (' SMAD7%0'  ' RHOA%0')  (' SMAD7%0'  ' BMPR2%0')  (' SMAD7%0'  ' PARD6A%0')  (' SMAD7%0'  ' DAAM1%0')  (' SMAD7%0'  ' SFRP1_g%0')  (' SMAD7%0'  ' PPM1A%0')  (' SMAD7%0'  ' CFL_f%0')  (' SMAD7%0'  ' PAK1%0')  (' SMAD7%0'  ' MAP3K11%0')  (' SMAD7%0'  ' MAP3K4%0')  (' SMAD7%0'  ' LIMK1%0')  (' SMAD7%0'  ' ROCK1%0')  (' SMAD7%0'  ' ITCH%0')  (' SMAD7%0'  ' ARHGAP24%0')  (' SMAD7%0'  ' TIAM1%0')  (' SMAD7%0'  ' RND3%0')  (' SMAD7%0'  ' MAPK8IP3%0')  (' SMAD7%0'  ' MXD1%0')  (' SMAD7%0'  ' PIP3%0')  (' SMAD6%0'  ' SRC%0')  (' SMAD6%0'  ' CSK%0')  (' SMAD6%0'  ' CHUK%0')  (' SMAD6%0'  ' RAC_f%0')  (' SMAD6%0'  ' DUSP1%0')  (' SMAD6%0'  ' TGFBR2%0')  (' SMAD6%0'  ' ILR_f%0')  (' SMAD6%0'  ' SYK%0')  (' SMAD6%0'  ' IRAK1%0')  (' SMAD6%0'  ' SHC1%0')  (' SMAD6%0'  ' JAK_f%0')  (' SMAD6%0'  ' CBPp300_c%0')  (' SMAD6%0'  ' SKP2%0')  (' SMAD6%0'  ' TP53%0')  (' SMAD6%0'  ' SMAD7%0')  (' SMAD6%0'  ' DKK_f%0')  (' SMAD6%0'  ' FOXO_f%0')  (' SMAD6%0'  ' TCF7_f%0')  (' SMAD6%0'  ' DKK_g%0')  (' SMAD6%0'  ' MYC%0')  (' SMAD6%0'  ' CCND1%0')  (' SMAD6%0'  ' EGR1%0')  (' SMAD6%0'  ' MMP_f%0')  (' SMAD6%0'  ' PTEN_g%0')  (' SMAD6%0'  ' RTPK_f%0')  (' SMAD6%0'  ' CTNNB1%0')  (' SMAD6%0'  'LEF1%0')  (' SMAD6%0'  'SFRP1%0')  (' SMAD6%0'  'FZD_f%0')  (' SMAD6%0'  ' CASP8%0')  (' SMAD6%0'  ' REL_f%0')  (' SMAD6%0'  ' NFKB_f%0')  (' SMAD6%0'  ' DVL_f%0')  (' SMAD6%0'  ' LRP_f%0')  (' SMAD6%0'  ' BTRC%0')  (' SMAD6%0'  ' CK1_f%0')  (' SMAD6%0'  ' AXIN1%0')  (' SMAD6%0'  ' mTORC2_c%0')  (' SMAD6%0'  ' PDPK1%0')  (' SMAD6%0'  ' MEK_f%0')  (' SMAD6%0'  ' CYCS%0')  (' SMAD6%0'  ' CASP9%0')  (' SMAD6%0'  ' GSK3_f%0')  (' SMAD6%0'  ' IRS1%0')  (' SMAD6%0'  ' MDM2%0')  (' SMAD6%0'  ' AKT_f%0')  (' SMAD6%0'  ' BCL2%0')  (' SMAD6%0'  ' RAF_f%0')  (' SMAD6%0'  ' mTORC1_c%0')  (' SMAD6%0'  ' RHEB%0')  (' SMAD6%0'  ' RTPK_g%0')  (' SMAD6%0'  ' PTEN%0')  (' SMAD6%0'  ' CASP3%0')  (' SMAD6%0'  ' PIK3CA%0')  (' SMAD6%0'  ' CREBBP%0')  (' SMAD6%0'  ' PTPN11%0')  (' SMAD6%0'  ' KRAS%0')  (' SMAD6%0'  ' MAP2K4%0')  (' SMAD6%0'  ' MAP2K7%0')  (' SMAD6%0'  ' MAPK14%0')  (' SMAD6%0'  ' JNK_f%0')  (' SMAD6%0'  ' MAP2K3%0')  (' SMAD6%0'  ' ERK_f%0')  (' SMAD6%0'  ' LIF%0')  (' SMAD6%0'  ' PPP1CA%0')  (' SMAD6%0'  ' GAB_f%0')  (' SMAD6%0'  ' SOS1%0')  (' SMAD6%0'  ' PRKCA%0')  (' SMAD6%0'  ' VAV1%0')  (' SMAD6%0'  ' PLCG1%0')  (' SMAD6%0'  ' PRKCD%0')  (' SMAD6%0'  ' RSK_f%0')  (' SMAD6%0'  ' S6K_f%0')  (' SMAD6%0'  ' PLK1%0')  (' SMAD6%0'  ' ILK%0')  (' SMAD6%0'  ' SOCS1%0')  (' SMAD6%0'  ' DUSP6%0')  (' SMAD6%0'  ' STAT3%0')  (' SMAD6%0'  ' LIMK2%0')  (' SMAD6%0'  ' EP300%0')  (' SMAD6%0'  ' STAT1%0')  (' SMAD6%0'  ' IKBKB%0')  (' SMAD6%0'  ' SRF%0')  (' SMAD6%0'  ' PIAS1%0')  (' SMAD6%0'  ' TRAF6%0')  (' SMAD6%0'  ' SOCS1_g%0')  (' SMAD6%0'  ' ISGF3_c%0')  (' SMAD6%0'  ' STAT2%0')  (' SMAD6%0'  ' CFLAR%0')  (' SMAD6%0'  ' SMAD2%0')  (' SMAD6%0'  ' MDM2_g%0')  (' SMAD6%0'  ' BAX%0')  (' SMAD6%0'  ' PRKACA%0')  (' SMAD6%0'  ' TGFB1%0')  (' SMAD6%0'  ' MAP3K8%0')  (' SMAD6%0'  ' TSC_f%0')  (' SMAD6%0'  ' SMAD4%0')  (' SMAD6%0'  ' BAD%0')  (' SMAD6%0'  ' MAP3K5%0')  (' SMAD6%0'  ' AKT1S1%0')  (' SMAD6%0'  ' SKI%0')  (' SMAD6%0'  ' SMAD3%0')  (' SMAD6%0'  ' MAPKAPK2%0')  (' SMAD6%0'  ' DUSP1_g%0')  (' SMAD6%0'  ' MSK_f%0')  (' SMAD6%0'  ' GRAP2%0')  (' SMAD6%0'  ' TAB_f%0')  (' SMAD6%0'  ' ATF2%0')  (' SMAD6%0'  ' SMAD5%0')  (' SMAD6%0'  ' SMAD1%0')  (' SMAD6%0'  ' FOS%0')  (' SMAD6%0'  ' JUN%0')  (' SMAD6%0'  ' MAP3K7%0')  (' SMAD6%0'  ' NLK%0')  (' SMAD6%0'  ' SMAD7_g%0')  (' SMAD6%0'  ' SMAD6_g%0')  (' SMAD6%0'  ' AP1_c%0')  (' SMAD6%0'  ' ACVR1%0')  (' SMAD6%0'  ' PTPN6%0')  (' SMAD6%0'  ' CDC42%0')  (' SMAD6%0'  ' GRB2%0')  (' SMAD6%0'  ' TGFBR1%0')  (' SMAD6%0'  ' SMURF1%0')  (' SMAD6%0'  ' SMURF2%0')  (' SMAD6%0'  ' RHOA%0')  (' SMAD6%0'  ' BMPR2%0')  (' SMAD6%0'  ' PARD6A%0')  (' SMAD6%0'  ' DAAM1%0')  (' SMAD6%0'  ' SFRP1_g%0')  (' SMAD6%0'  ' PPM1A%0')  (' SMAD6%0'  ' CFL_f%0')  (' SMAD6%0'  ' PAK1%0')  (' SMAD6%0'  ' MAP3K11%0')  (' SMAD6%0'  ' MAP3K4%0')  (' SMAD6%0'  ' LIMK1%0')  (' SMAD6%0'  ' ROCK1%0')  (' SMAD6%0'  ' ITCH%0')  (' SMAD6%0'  ' ARHGAP24%0')  (' SMAD6%0'  ' TIAM1%0')  (' SMAD6%0'  ' RND3%0')  (' SMAD6%0'  ' MAPK8IP3%0')  (' SMAD6%0'  ' MXD1%0')  (' SMAD6%0'  ' PIP3%0')  (' DKK_f%0'  ' SRC%0')  (' DKK_f%0'  ' CSK%0')  (' DKK_f%0'  ' CHUK%0')  (' DKK_f%0'  ' RAC_f%0')  (' DKK_f%0'  ' DUSP1%0')  (' DKK_f%0'  ' TGFBR2%0')  (' DKK_f%0'  ' ILR_f%0')  (' DKK_f%0'  ' SYK%0')  (' DKK_f%0'  ' IRAK1%0')  (' DKK_f%0'  ' SHC1%0')  (' DKK_f%0'  ' JAK_f%0')  (' DKK_f%0'  ' CBPp300_c%0')  (' DKK_f%0'  ' SKP2%0')  (' DKK_f%0'  ' TP53%0')  (' DKK_f%0'  ' SMAD7%0')  (' DKK_f%0'  ' SMAD6%0')  (' DKK_f%0'  ' FOXO_f%0')  (' DKK_f%0'  ' TCF7_f%0')  (' DKK_f%0'  ' DKK_g%0')  (' DKK_f%0'  ' MYC%0')  (' DKK_f%0'  ' CCND1%0')  (' DKK_f%0'  ' EGR1%0')  (' DKK_f%0'  ' MMP_f%0')  (' DKK_f%0'  ' PTEN_g%0')  (' DKK_f%0'  ' RTPK_f%0')  (' DKK_f%0'  ' CTNNB1%0')  (' DKK_f%0'  'LEF1%0')  (' DKK_f%0'  'SFRP1%0')  (' DKK_f%0'  'FZD_f%0')  (' DKK_f%0'  ' CASP8%0')  (' DKK_f%0'  ' REL_f%0')  (' DKK_f%0'  ' NFKB_f%0')  (' DKK_f%0'  ' DVL_f%0')  (' DKK_f%0'  ' LRP_f%0')  (' DKK_f%0'  ' BTRC%0')  (' DKK_f%0'  ' CK1_f%0')  (' DKK_f%0'  ' AXIN1%0')  (' DKK_f%0'  ' mTORC2_c%0')  (' DKK_f%0'  ' PDPK1%0')  (' DKK_f%0'  ' MEK_f%0')  (' DKK_f%0'  ' CYCS%0')  (' DKK_f%0'  ' CASP9%0')  (' DKK_f%0'  ' GSK3_f%0')  (' DKK_f%0'  ' IRS1%0')  (' DKK_f%0'  ' MDM2%0')  (' DKK_f%0'  ' AKT_f%0')  (' DKK_f%0'  ' BCL2%0')  (' DKK_f%0'  ' RAF_f%0')  (' DKK_f%0'  ' mTORC1_c%0')  (' DKK_f%0'  ' RHEB%0')  (' DKK_f%0'  ' RTPK_g%0')  (' DKK_f%0'  ' PTEN%0')  (' DKK_f%0'  ' CASP3%0')  (' DKK_f%0'  ' PIK3CA%0')  (' DKK_f%0'  ' CREBBP%0')  (' DKK_f%0'  ' PTPN11%0')  (' DKK_f%0'  ' KRAS%0')  (' DKK_f%0'  ' MAP2K4%0')  (' DKK_f%0'  ' MAP2K7%0')  (' DKK_f%0'  ' MAPK14%0')  (' DKK_f%0'  ' JNK_f%0')  (' DKK_f%0'  ' MAP2K3%0')  (' DKK_f%0'  ' ERK_f%0')  (' DKK_f%0'  ' LIF%0')  (' DKK_f%0'  ' PPP1CA%0')  (' DKK_f%0'  ' GAB_f%0')  (' DKK_f%0'  ' SOS1%0')  (' DKK_f%0'  ' PRKCA%0')  (' DKK_f%0'  ' VAV1%0')  (' DKK_f%0'  ' PLCG1%0')  (' DKK_f%0'  ' PRKCD%0')  (' DKK_f%0'  ' RSK_f%0')  (' DKK_f%0'  ' S6K_f%0')  (' DKK_f%0'  ' PLK1%0')  (' DKK_f%0'  ' ILK%0')  (' DKK_f%0'  ' SOCS1%0')  (' DKK_f%0'  ' DUSP6%0')  (' DKK_f%0'  ' STAT3%0')  (' DKK_f%0'  ' LIMK2%0')  (' DKK_f%0'  ' EP300%0')  (' DKK_f%0'  ' STAT1%0')  (' DKK_f%0'  ' IKBKB%0')  (' DKK_f%0'  ' SRF%0')  (' DKK_f%0'  ' PIAS1%0')  (' DKK_f%0'  ' TRAF6%0')  (' DKK_f%0'  ' SOCS1_g%0')  (' DKK_f%0'  ' ISGF3_c%0')  (' DKK_f%0'  ' STAT2%0')  (' DKK_f%0'  ' CFLAR%0')  (' DKK_f%0'  ' SMAD2%0')  (' DKK_f%0'  ' MDM2_g%0')  (' DKK_f%0'  ' BAX%0')  (' DKK_f%0'  ' PRKACA%0')  (' DKK_f%0'  ' TGFB1%0')  (' DKK_f%0'  ' MAP3K8%0')  (' DKK_f%0'  ' TSC_f%0')  (' DKK_f%0'  ' SMAD4%0')  (' DKK_f%0'  ' BAD%0')  (' DKK_f%0'  ' MAP3K5%0')  (' DKK_f%0'  ' AKT1S1%0')  (' DKK_f%0'  ' SKI%0')  (' DKK_f%0'  ' SMAD3%0')  (' DKK_f%0'  ' MAPKAPK2%0')  (' DKK_f%0'  ' DUSP1_g%0')  (' DKK_f%0'  ' MSK_f%0')  (' DKK_f%0'  ' GRAP2%0')  (' DKK_f%0'  ' TAB_f%0')  (' DKK_f%0'  ' ATF2%0')  (' DKK_f%0'  ' SMAD5%0')  (' DKK_f%0'  ' SMAD1%0')  (' DKK_f%0'  ' FOS%0')  (' DKK_f%0'  ' JUN%0')  (' DKK_f%0'  ' MAP3K7%0')  (' DKK_f%0'  ' NLK%0')  (' DKK_f%0'  ' SMAD7_g%0')  (' DKK_f%0'  ' SMAD6_g%0')  (' DKK_f%0'  ' AP1_c%0')  (' DKK_f%0'  ' ACVR1%0')  (' DKK_f%0'  ' PTPN6%0')  (' DKK_f%0'  ' CDC42%0')  (' DKK_f%0'  ' GRB2%0')  (' DKK_f%0'  ' TGFBR1%0')  (' DKK_f%0'  ' SMURF1%0')  (' DKK_f%0'  ' SMURF2%0')  (' DKK_f%0'  ' RHOA%0')  (' DKK_f%0'  ' BMPR2%0')  (' DKK_f%0'  ' PARD6A%0')  (' DKK_f%0'  ' DAAM1%0')  (' DKK_f%0'  ' SFRP1_g%0')  (' DKK_f%0'  ' PPM1A%0')  (' DKK_f%0'  ' CFL_f%0')  (' DKK_f%0'  ' PAK1%0')  (' DKK_f%0'  ' MAP3K11%0')  (' DKK_f%0'  ' MAP3K4%0')  (' DKK_f%0'  ' LIMK1%0')  (' DKK_f%0'  ' ROCK1%0')  (' DKK_f%0'  ' ITCH%0')  (' DKK_f%0'  ' ARHGAP24%0')  (' DKK_f%0'  ' TIAM1%0')  (' DKK_f%0'  ' RND3%0')  (' DKK_f%0'  ' MAPK8IP3%0')  (' DKK_f%0'  ' MXD1%0')  (' DKK_f%0'  ' PIP3%0')  (' FOXO_f%0'  ' SRC%0')  (' FOXO_f%0'  ' CSK%0')  (' FOXO_f%0'  ' CHUK%0')  (' FOXO_f%0'  ' RAC_f%0')  (' FOXO_f%0'  ' DUSP1%0')  (' FOXO_f%0'  ' TGFBR2%0')  (' FOXO_f%0'  ' ILR_f%0')  (' FOXO_f%0'  ' SYK%0')  (' FOXO_f%0'  ' IRAK1%0')  (' FOXO_f%0'  ' SHC1%0')  (' FOXO_f%0'  ' JAK_f%0')  (' FOXO_f%0'  ' CBPp300_c%0')  (' FOXO_f%0'  ' SKP2%0')  (' FOXO_f%0'  ' TP53%0')  (' FOXO_f%0'  ' SMAD7%0')  (' FOXO_f%0'  ' SMAD6%0')  (' FOXO_f%0'  ' DKK_f%0')  (' FOXO_f%0'  ' TCF7_f%0')  (' FOXO_f%0'  ' DKK_g%0')  (' FOXO_f%0'  ' MYC%0')  (' FOXO_f%0'  ' CCND1%0')  (' FOXO_f%0'  ' EGR1%0')  (' FOXO_f%0'  ' MMP_f%0')  (' FOXO_f%0'  ' PTEN_g%0')  (' FOXO_f%0'  ' RTPK_f%0')  (' FOXO_f%0'  ' CTNNB1%0')  (' FOXO_f%0'  'LEF1%0')  (' FOXO_f%0'  'SFRP1%0')  (' FOXO_f%0'  'FZD_f%0')  (' FOXO_f%0'  ' CASP8%0')  (' FOXO_f%0'  ' REL_f%0')  (' FOXO_f%0'  ' NFKB_f%0')  (' FOXO_f%0'  ' DVL_f%0')  (' FOXO_f%0'  ' LRP_f%0')  (' FOXO_f%0'  ' BTRC%0')  (' FOXO_f%0'  ' CK1_f%0')  (' FOXO_f%0'  ' AXIN1%0')  (' FOXO_f%0'  ' mTORC2_c%0')  (' FOXO_f%0'  ' PDPK1%0')  (' FOXO_f%0'  ' MEK_f%0')  (' FOXO_f%0'  ' CYCS%0')  (' FOXO_f%0'  ' CASP9%0')  (' FOXO_f%0'  ' GSK3_f%0')  (' FOXO_f%0'  ' IRS1%0')  (' FOXO_f%0'  ' MDM2%0')  (' FOXO_f%0'  ' AKT_f%0')  (' FOXO_f%0'  ' BCL2%0')  (' FOXO_f%0'  ' RAF_f%0')  (' FOXO_f%0'  ' mTORC1_c%0')  (' FOXO_f%0'  ' RHEB%0')  (' FOXO_f%0'  ' RTPK_g%0')  (' FOXO_f%0'  ' PTEN%0')  (' FOXO_f%0'  ' CASP3%0')  (' FOXO_f%0'  ' PIK3CA%0')  (' FOXO_f%0'  ' CREBBP%0')  (' FOXO_f%0'  ' PTPN11%0')  (' FOXO_f%0'  ' KRAS%0')  (' FOXO_f%0'  ' MAP2K4%0')  (' FOXO_f%0'  ' MAP2K7%0')  (' FOXO_f%0'  ' MAPK14%0')  (' FOXO_f%0'  ' JNK_f%0')  (' FOXO_f%0'  ' MAP2K3%0')  (' FOXO_f%0'  ' ERK_f%0')  (' FOXO_f%0'  ' LIF%0')  (' FOXO_f%0'  ' PPP1CA%0')  (' FOXO_f%0'  ' GAB_f%0')  (' FOXO_f%0'  ' SOS1%0')  (' FOXO_f%0'  ' PRKCA%0')  (' FOXO_f%0'  ' VAV1%0')  (' FOXO_f%0'  ' PLCG1%0')  (' FOXO_f%0'  ' PRKCD%0')  (' FOXO_f%0'  ' RSK_f%0')  (' FOXO_f%0'  ' S6K_f%0')  (' FOXO_f%0'  ' PLK1%0')  (' FOXO_f%0'  ' ILK%0')  (' FOXO_f%0'  ' SOCS1%0')  (' FOXO_f%0'  ' DUSP6%0')  (' FOXO_f%0'  ' STAT3%0')  (' FOXO_f%0'  ' LIMK2%0')  (' FOXO_f%0'  ' EP300%0')  (' FOXO_f%0'  ' STAT1%0')  (' FOXO_f%0'  ' IKBKB%0')  (' FOXO_f%0'  ' SRF%0')  (' FOXO_f%0'  ' PIAS1%0')  (' FOXO_f%0'  ' TRAF6%0')  (' FOXO_f%0'  ' SOCS1_g%0')  (' FOXO_f%0'  ' ISGF3_c%0')  (' FOXO_f%0'  ' STAT2%0')  (' FOXO_f%0'  ' CFLAR%0')  (' FOXO_f%0'  ' SMAD2%0')  (' FOXO_f%0'  ' MDM2_g%0')  (' FOXO_f%0'  ' BAX%0')  (' FOXO_f%0'  ' PRKACA%0')  (' FOXO_f%0'  ' TGFB1%0')  (' FOXO_f%0'  ' MAP3K8%0')  (' FOXO_f%0'  ' TSC_f%0')  (' FOXO_f%0'  ' SMAD4%0')  (' FOXO_f%0'  ' BAD%0')  (' FOXO_f%0'  ' MAP3K5%0')  (' FOXO_f%0'  ' AKT1S1%0')  (' FOXO_f%0'  ' SKI%0')  (' FOXO_f%0'  ' SMAD3%0')  (' FOXO_f%0'  ' MAPKAPK2%0')  (' FOXO_f%0'  ' DUSP1_g%0')  (' FOXO_f%0'  ' MSK_f%0')  (' FOXO_f%0'  ' GRAP2%0')  (' FOXO_f%0'  ' TAB_f%0')  (' FOXO_f%0'  ' ATF2%0')  (' FOXO_f%0'  ' SMAD5%0')  (' FOXO_f%0'  ' SMAD1%0')  (' FOXO_f%0'  ' FOS%0')  (' FOXO_f%0'  ' JUN%0')  (' FOXO_f%0'  ' MAP3K7%0')  (' FOXO_f%0'  ' NLK%0')  (' FOXO_f%0'  ' SMAD7_g%0')  (' FOXO_f%0'  ' SMAD6_g%0')  (' FOXO_f%0'  ' AP1_c%0')  (' FOXO_f%0'  ' ACVR1%0')  (' FOXO_f%0'  ' PTPN6%0')  (' FOXO_f%0'  ' CDC42%0')  (' FOXO_f%0'  ' GRB2%0')  (' FOXO_f%0'  ' TGFBR1%0')  (' FOXO_f%0'  ' SMURF1%0')  (' FOXO_f%0'  ' SMURF2%0')  (' FOXO_f%0'  ' RHOA%0')  (' FOXO_f%0'  ' BMPR2%0')  (' FOXO_f%0'  ' PARD6A%0')  (' FOXO_f%0'  ' DAAM1%0')  (' FOXO_f%0'  ' SFRP1_g%0')  (' FOXO_f%0'  ' PPM1A%0')  (' FOXO_f%0'  ' CFL_f%0')  (' FOXO_f%0'  ' PAK1%0')  (' FOXO_f%0'  ' MAP3K11%0')  (' FOXO_f%0'  ' MAP3K4%0')  (' FOXO_f%0'  ' LIMK1%0')  (' FOXO_f%0'  ' ROCK1%0')  (' FOXO_f%0'  ' ITCH%0')  (' FOXO_f%0'  ' ARHGAP24%0')  (' FOXO_f%0'  ' TIAM1%0')  (' FOXO_f%0'  ' RND3%0')  (' FOXO_f%0'  ' MAPK8IP3%0')  (' FOXO_f%0'  ' MXD1%0')  (' FOXO_f%0'  ' PIP3%0')  (' TCF7_f%0'  ' SRC%0')  (' TCF7_f%0'  ' CSK%0')  (' TCF7_f%0'  ' CHUK%0')  (' TCF7_f%0'  ' RAC_f%0')  (' TCF7_f%0'  ' DUSP1%0')  (' TCF7_f%0'  ' TGFBR2%0')  (' TCF7_f%0'  ' ILR_f%0')  (' TCF7_f%0'  ' SYK%0')  (' TCF7_f%0'  ' IRAK1%0')  (' TCF7_f%0'  ' SHC1%0')  (' TCF7_f%0'  ' JAK_f%0')  (' TCF7_f%0'  ' CBPp300_c%0')  (' TCF7_f%0'  ' SKP2%0')  (' TCF7_f%0'  ' TP53%0')  (' TCF7_f%0'  ' SMAD7%0')  (' TCF7_f%0'  ' SMAD6%0')  (' TCF7_f%0'  ' DKK_f%0')  (' TCF7_f%0'  ' FOXO_f%0')  (' TCF7_f%0'  ' DKK_g%0')  (' TCF7_f%0'  ' MYC%0')  (' TCF7_f%0'  ' CCND1%0')  (' TCF7_f%0'  ' EGR1%0')  (' TCF7_f%0'  ' MMP_f%0')  (' TCF7_f%0'  ' PTEN_g%0')  (' TCF7_f%0'  ' RTPK_f%0')  (' TCF7_f%0'  ' CTNNB1%0')  (' TCF7_f%0'  'LEF1%0')  (' TCF7_f%0'  'SFRP1%0')  (' TCF7_f%0'  'FZD_f%0')  (' TCF7_f%0'  ' CASP8%0')  (' TCF7_f%0'  ' REL_f%0')  (' TCF7_f%0'  ' NFKB_f%0')  (' TCF7_f%0'  ' DVL_f%0')  (' TCF7_f%0'  ' LRP_f%0')  (' TCF7_f%0'  ' BTRC%0')  (' TCF7_f%0'  ' CK1_f%0')  (' TCF7_f%0'  ' AXIN1%0')  (' TCF7_f%0'  ' mTORC2_c%0')  (' TCF7_f%0'  ' PDPK1%0')  (' TCF7_f%0'  ' MEK_f%0')  (' TCF7_f%0'  ' CYCS%0')  (' TCF7_f%0'  ' CASP9%0')  (' TCF7_f%0'  ' GSK3_f%0')  (' TCF7_f%0'  ' IRS1%0')  (' TCF7_f%0'  ' MDM2%0')  (' TCF7_f%0'  ' AKT_f%0')  (' TCF7_f%0'  ' BCL2%0')  (' TCF7_f%0'  ' RAF_f%0')  (' TCF7_f%0'  ' mTORC1_c%0')  (' TCF7_f%0'  ' RHEB%0')  (' TCF7_f%0'  ' RTPK_g%0')  (' TCF7_f%0'  ' PTEN%0')  (' TCF7_f%0'  ' CASP3%0')  (' TCF7_f%0'  ' PIK3CA%0')  (' TCF7_f%0'  ' CREBBP%0')  (' TCF7_f%0'  ' PTPN11%0')  (' TCF7_f%0'  ' KRAS%0')  (' TCF7_f%0'  ' MAP2K4%0')  (' TCF7_f%0'  ' MAP2K7%0')  (' TCF7_f%0'  ' MAPK14%0')  (' TCF7_f%0'  ' JNK_f%0')  (' TCF7_f%0'  ' MAP2K3%0')  (' TCF7_f%0'  ' ERK_f%0')  (' TCF7_f%0'  ' LIF%0')  (' TCF7_f%0'  ' PPP1CA%0')  (' TCF7_f%0'  ' GAB_f%0')  (' TCF7_f%0'  ' SOS1%0')  (' TCF7_f%0'  ' PRKCA%0')  (' TCF7_f%0'  ' VAV1%0')  (' TCF7_f%0'  ' PLCG1%0')  (' TCF7_f%0'  ' PRKCD%0')  (' TCF7_f%0'  ' RSK_f%0')  (' TCF7_f%0'  ' S6K_f%0')  (' TCF7_f%0'  ' PLK1%0')  (' TCF7_f%0'  ' ILK%0')  (' TCF7_f%0'  ' SOCS1%0')  (' TCF7_f%0'  ' DUSP6%0')  (' TCF7_f%0'  ' STAT3%0')  (' TCF7_f%0'  ' LIMK2%0')  (' TCF7_f%0'  ' EP300%0')  (' TCF7_f%0'  ' STAT1%0')  (' TCF7_f%0'  ' IKBKB%0')  (' TCF7_f%0'  ' SRF%0')  (' TCF7_f%0'  ' PIAS1%0')  (' TCF7_f%0'  ' TRAF6%0')  (' TCF7_f%0'  ' SOCS1_g%0')  (' TCF7_f%0'  ' ISGF3_c%0')  (' TCF7_f%0'  ' STAT2%0')  (' TCF7_f%0'  ' CFLAR%0')  (' TCF7_f%0'  ' SMAD2%0')  (' TCF7_f%0'  ' MDM2_g%0')  (' TCF7_f%0'  ' BAX%0')  (' TCF7_f%0'  ' PRKACA%0')  (' TCF7_f%0'  ' TGFB1%0')  (' TCF7_f%0'  ' MAP3K8%0')  (' TCF7_f%0'  ' TSC_f%0')  (' TCF7_f%0'  ' SMAD4%0')  (' TCF7_f%0'  ' BAD%0')  (' TCF7_f%0'  ' MAP3K5%0')  (' TCF7_f%0'  ' AKT1S1%0')  (' TCF7_f%0'  ' SKI%0')  (' TCF7_f%0'  ' SMAD3%0')  (' TCF7_f%0'  ' MAPKAPK2%0')  (' TCF7_f%0'  ' DUSP1_g%0')  (' TCF7_f%0'  ' MSK_f%0')  (' TCF7_f%0'  ' GRAP2%0')  (' TCF7_f%0'  ' TAB_f%0')  (' TCF7_f%0'  ' ATF2%0')  (' TCF7_f%0'  ' SMAD5%0')  (' TCF7_f%0'  ' SMAD1%0')  (' TCF7_f%0'  ' FOS%0')  (' TCF7_f%0'  ' JUN%0')  (' TCF7_f%0'  ' MAP3K7%0')  (' TCF7_f%0'  ' NLK%0')  (' TCF7_f%0'  ' SMAD7_g%0')  (' TCF7_f%0'  ' SMAD6_g%0')  (' TCF7_f%0'  ' AP1_c%0')  (' TCF7_f%0'  ' ACVR1%0')  (' TCF7_f%0'  ' PTPN6%0')  (' TCF7_f%0'  ' CDC42%0')  (' TCF7_f%0'  ' GRB2%0')  (' TCF7_f%0'  ' TGFBR1%0')  (' TCF7_f%0'  ' SMURF1%0')  (' TCF7_f%0'  ' SMURF2%0')  (' TCF7_f%0'  ' RHOA%0')  (' TCF7_f%0'  ' BMPR2%0')  (' TCF7_f%0'  ' PARD6A%0')  (' TCF7_f%0'  ' DAAM1%0')  (' TCF7_f%0'  ' SFRP1_g%0')  (' TCF7_f%0'  ' PPM1A%0')  (' TCF7_f%0'  ' CFL_f%0')  (' TCF7_f%0'  ' PAK1%0')  (' TCF7_f%0'  ' MAP3K11%0')  (' TCF7_f%0'  ' MAP3K4%0')  (' TCF7_f%0'  ' LIMK1%0')  (' TCF7_f%0'  ' ROCK1%0')  (' TCF7_f%0'  ' ITCH%0')  (' TCF7_f%0'  ' ARHGAP24%0')  (' TCF7_f%0'  ' TIAM1%0')  (' TCF7_f%0'  ' RND3%0')  (' TCF7_f%0'  ' MAPK8IP3%0')  (' TCF7_f%0'  ' MXD1%0')  (' TCF7_f%0'  ' PIP3%0')  (' DKK_g%0'  ' SRC%0')  (' DKK_g%0'  ' CSK%0')  (' DKK_g%0'  ' CHUK%0')  (' DKK_g%0'  ' RAC_f%0')  (' DKK_g%0'  ' DUSP1%0')  (' DKK_g%0'  ' TGFBR2%0')  (' DKK_g%0'  ' ILR_f%0')  (' DKK_g%0'  ' SYK%0')  (' DKK_g%0'  ' IRAK1%0')  (' DKK_g%0'  ' SHC1%0')  (' DKK_g%0'  ' JAK_f%0')  (' DKK_g%0'  ' CBPp300_c%0')  (' DKK_g%0'  ' SKP2%0')  (' DKK_g%0'  ' TP53%0')  (' DKK_g%0'  ' SMAD7%0')  (' DKK_g%0'  ' SMAD6%0')  (' DKK_g%0'  ' DKK_f%0')  (' DKK_g%0'  ' FOXO_f%0')  (' DKK_g%0'  ' TCF7_f%0')  (' DKK_g%0'  ' MYC%0')  (' DKK_g%0'  ' CCND1%0')  (' DKK_g%0'  ' EGR1%0')  (' DKK_g%0'  ' MMP_f%0')  (' DKK_g%0'  ' PTEN_g%0')  (' DKK_g%0'  ' RTPK_f%0')  (' DKK_g%0'  ' CTNNB1%0')  (' DKK_g%0'  'LEF1%0')  (' DKK_g%0'  'SFRP1%0')  (' DKK_g%0'  'FZD_f%0')  (' DKK_g%0'  ' CASP8%0')  (' DKK_g%0'  ' REL_f%0')  (' DKK_g%0'  ' NFKB_f%0')  (' DKK_g%0'  ' DVL_f%0')  (' DKK_g%0'  ' LRP_f%0')  (' DKK_g%0'  ' BTRC%0')  (' DKK_g%0'  ' CK1_f%0')  (' DKK_g%0'  ' AXIN1%0')  (' DKK_g%0'  ' mTORC2_c%0')  (' DKK_g%0'  ' PDPK1%0')  (' DKK_g%0'  ' MEK_f%0')  (' DKK_g%0'  ' CYCS%0')  (' DKK_g%0'  ' CASP9%0')  (' DKK_g%0'  ' GSK3_f%0')  (' DKK_g%0'  ' IRS1%0')  (' DKK_g%0'  ' MDM2%0')  (' DKK_g%0'  ' AKT_f%0')  (' DKK_g%0'  ' BCL2%0')  (' DKK_g%0'  ' RAF_f%0')  (' DKK_g%0'  ' mTORC1_c%0')  (' DKK_g%0'  ' RHEB%0')  (' DKK_g%0'  ' RTPK_g%0')  (' DKK_g%0'  ' PTEN%0')  (' DKK_g%0'  ' CASP3%0')  (' DKK_g%0'  ' PIK3CA%0')  (' DKK_g%0'  ' CREBBP%0')  (' DKK_g%0'  ' PTPN11%0')  (' DKK_g%0'  ' KRAS%0')  (' DKK_g%0'  ' MAP2K4%0')  (' DKK_g%0'  ' MAP2K7%0')  (' DKK_g%0'  ' MAPK14%0')  (' DKK_g%0'  ' JNK_f%0')  (' DKK_g%0'  ' MAP2K3%0')  (' DKK_g%0'  ' ERK_f%0')  (' DKK_g%0'  ' LIF%0')  (' DKK_g%0'  ' PPP1CA%0')  (' DKK_g%0'  ' GAB_f%0')  (' DKK_g%0'  ' SOS1%0')  (' DKK_g%0'  ' PRKCA%0')  (' DKK_g%0'  ' VAV1%0')  (' DKK_g%0'  ' PLCG1%0')  (' DKK_g%0'  ' PRKCD%0')  (' DKK_g%0'  ' RSK_f%0')  (' DKK_g%0'  ' S6K_f%0')  (' DKK_g%0'  ' PLK1%0')  (' DKK_g%0'  ' ILK%0')  (' DKK_g%0'  ' SOCS1%0')  (' DKK_g%0'  ' DUSP6%0')  (' DKK_g%0'  ' STAT3%0')  (' DKK_g%0'  ' LIMK2%0')  (' DKK_g%0'  ' EP300%0')  (' DKK_g%0'  ' STAT1%0')  (' DKK_g%0'  ' IKBKB%0')  (' DKK_g%0'  ' SRF%0')  (' DKK_g%0'  ' PIAS1%0')  (' DKK_g%0'  ' TRAF6%0')  (' DKK_g%0'  ' SOCS1_g%0')  (' DKK_g%0'  ' ISGF3_c%0')  (' DKK_g%0'  ' STAT2%0')  (' DKK_g%0'  ' CFLAR%0')  (' DKK_g%0'  ' SMAD2%0')  (' DKK_g%0'  ' MDM2_g%0')  (' DKK_g%0'  ' BAX%0')  (' DKK_g%0'  ' PRKACA%0')  (' DKK_g%0'  ' TGFB1%0')  (' DKK_g%0'  ' MAP3K8%0')  (' DKK_g%0'  ' TSC_f%0')  (' DKK_g%0'  ' SMAD4%0')  (' DKK_g%0'  ' BAD%0')  (' DKK_g%0'  ' MAP3K5%0')  (' DKK_g%0'  ' AKT1S1%0')  (' DKK_g%0'  ' SKI%0')  (' DKK_g%0'  ' SMAD3%0')  (' DKK_g%0'  ' MAPKAPK2%0')  (' DKK_g%0'  ' DUSP1_g%0')  (' DKK_g%0'  ' MSK_f%0')  (' DKK_g%0'  ' GRAP2%0')  (' DKK_g%0'  ' TAB_f%0')  (' DKK_g%0'  ' ATF2%0')  (' DKK_g%0'  ' SMAD5%0')  (' DKK_g%0'  ' SMAD1%0')  (' DKK_g%0'  ' FOS%0')  (' DKK_g%0'  ' JUN%0')  (' DKK_g%0'  ' MAP3K7%0')  (' DKK_g%0'  ' NLK%0')  (' DKK_g%0'  ' SMAD7_g%0')  (' DKK_g%0'  ' SMAD6_g%0')  (' DKK_g%0'  ' AP1_c%0')  (' DKK_g%0'  ' ACVR1%0')  (' DKK_g%0'  ' PTPN6%0')  (' DKK_g%0'  ' CDC42%0')  (' DKK_g%0'  ' GRB2%0')  (' DKK_g%0'  ' TGFBR1%0')  (' DKK_g%0'  ' SMURF1%0')  (' DKK_g%0'  ' SMURF2%0')  (' DKK_g%0'  ' RHOA%0')  (' DKK_g%0'  ' BMPR2%0')  (' DKK_g%0'  ' PARD6A%0')  (' DKK_g%0'  ' DAAM1%0')  (' DKK_g%0'  ' SFRP1_g%0')  (' DKK_g%0'  ' PPM1A%0')  (' DKK_g%0'  ' CFL_f%0')  (' DKK_g%0'  ' PAK1%0')  (' DKK_g%0'  ' MAP3K11%0')  (' DKK_g%0'  ' MAP3K4%0')  (' DKK_g%0'  ' LIMK1%0')  (' DKK_g%0'  ' ROCK1%0')  (' DKK_g%0'  ' ITCH%0')  (' DKK_g%0'  ' ARHGAP24%0')  (' DKK_g%0'  ' TIAM1%0')  (' DKK_g%0'  ' RND3%0')  (' DKK_g%0'  ' MAPK8IP3%0')  (' DKK_g%0'  ' MXD1%0')  (' DKK_g%0'  ' PIP3%0')  (' MYC%0'  ' SRC%0')  (' MYC%0'  ' CSK%0')  (' MYC%0'  ' CHUK%0')  (' MYC%0'  ' RAC_f%0')  (' MYC%0'  ' DUSP1%0')  (' MYC%0'  ' TGFBR2%0')  (' MYC%0'  ' ILR_f%0')  (' MYC%0'  ' SYK%0')  (' MYC%0'  ' IRAK1%0')  (' MYC%0'  ' SHC1%0')  (' MYC%0'  ' JAK_f%0')  (' MYC%0'  ' CBPp300_c%0')  (' MYC%0'  ' SKP2%0')  (' MYC%0'  ' TP53%0')  (' MYC%0'  ' SMAD7%0')  (' MYC%0'  ' SMAD6%0')  (' MYC%0'  ' DKK_f%0')  (' MYC%0'  ' FOXO_f%0')  (' MYC%0'  ' TCF7_f%0')  (' MYC%0'  ' DKK_g%0')  (' MYC%0'  ' CCND1%0')  (' MYC%0'  ' EGR1%0')  (' MYC%0'  ' MMP_f%0')  (' MYC%0'  ' PTEN_g%0')  (' MYC%0'  ' RTPK_f%0')  (' MYC%0'  ' CTNNB1%0')  (' MYC%0'  'LEF1%0')  (' MYC%0'  'SFRP1%0')  (' MYC%0'  'FZD_f%0')  (' MYC%0'  ' CASP8%0')  (' MYC%0'  ' REL_f%0')  (' MYC%0'  ' NFKB_f%0')  (' MYC%0'  ' DVL_f%0')  (' MYC%0'  ' LRP_f%0')  (' MYC%0'  ' BTRC%0')  (' MYC%0'  ' CK1_f%0')  (' MYC%0'  ' AXIN1%0')  (' MYC%0'  ' mTORC2_c%0')  (' MYC%0'  ' PDPK1%0')  (' MYC%0'  ' MEK_f%0')  (' MYC%0'  ' CYCS%0')  (' MYC%0'  ' CASP9%0')  (' MYC%0'  ' GSK3_f%0')  (' MYC%0'  ' IRS1%0')  (' MYC%0'  ' MDM2%0')  (' MYC%0'  ' AKT_f%0')  (' MYC%0'  ' BCL2%0')  (' MYC%0'  ' RAF_f%0')  (' MYC%0'  ' mTORC1_c%0')  (' MYC%0'  ' RHEB%0')  (' MYC%0'  ' RTPK_g%0')  (' MYC%0'  ' PTEN%0')  (' MYC%0'  ' CASP3%0')  (' MYC%0'  ' PIK3CA%0')  (' MYC%0'  ' CREBBP%0')  (' MYC%0'  ' PTPN11%0')  (' MYC%0'  ' KRAS%0')  (' MYC%0'  ' MAP2K4%0')  (' MYC%0'  ' MAP2K7%0')  (' MYC%0'  ' MAPK14%0')  (' MYC%0'  ' JNK_f%0')  (' MYC%0'  ' MAP2K3%0')  (' MYC%0'  ' ERK_f%0')  (' MYC%0'  ' LIF%0')  (' MYC%0'  ' PPP1CA%0')  (' MYC%0'  ' GAB_f%0')  (' MYC%0'  ' SOS1%0')  (' MYC%0'  ' PRKCA%0')  (' MYC%0'  ' VAV1%0')  (' MYC%0'  ' PLCG1%0')  (' MYC%0'  ' PRKCD%0')  (' MYC%0'  ' RSK_f%0')  (' MYC%0'  ' S6K_f%0')  (' MYC%0'  ' PLK1%0')  (' MYC%0'  ' ILK%0')  (' MYC%0'  ' SOCS1%0')  (' MYC%0'  ' DUSP6%0')  (' MYC%0'  ' STAT3%0')  (' MYC%0'  ' LIMK2%0')  (' MYC%0'  ' EP300%0')  (' MYC%0'  ' STAT1%0')  (' MYC%0'  ' IKBKB%0')  (' MYC%0'  ' SRF%0')  (' MYC%0'  ' PIAS1%0')  (' MYC%0'  ' TRAF6%0')  (' MYC%0'  ' SOCS1_g%0')  (' MYC%0'  ' ISGF3_c%0')  (' MYC%0'  ' STAT2%0')  (' MYC%0'  ' CFLAR%0')  (' MYC%0'  ' SMAD2%0')  (' MYC%0'  ' MDM2_g%0')  (' MYC%0'  ' BAX%0')  (' MYC%0'  ' PRKACA%0')  (' MYC%0'  ' TGFB1%0')  (' MYC%0'  ' MAP3K8%0')  (' MYC%0'  ' TSC_f%0')  (' MYC%0'  ' SMAD4%0')  (' MYC%0'  ' BAD%0')  (' MYC%0'  ' MAP3K5%0')  (' MYC%0'  ' AKT1S1%0')  (' MYC%0'  ' SKI%0')  (' MYC%0'  ' SMAD3%0')  (' MYC%0'  ' MAPKAPK2%0')  (' MYC%0'  ' DUSP1_g%0')  (' MYC%0'  ' MSK_f%0')  (' MYC%0'  ' GRAP2%0')  (' MYC%0'  ' TAB_f%0')  (' MYC%0'  ' ATF2%0')  (' MYC%0'  ' SMAD5%0')  (' MYC%0'  ' SMAD1%0')  (' MYC%0'  ' FOS%0')  (' MYC%0'  ' JUN%0')  (' MYC%0'  ' MAP3K7%0')  (' MYC%0'  ' NLK%0')  (' MYC%0'  ' SMAD7_g%0')  (' MYC%0'  ' SMAD6_g%0')  (' MYC%0'  ' AP1_c%0')  (' MYC%0'  ' ACVR1%0')  (' MYC%0'  ' PTPN6%0')  (' MYC%0'  ' CDC42%0')  (' MYC%0'  ' GRB2%0')  (' MYC%0'  ' TGFBR1%0')  (' MYC%0'  ' SMURF1%0')  (' MYC%0'  ' SMURF2%0')  (' MYC%0'  ' RHOA%0')  (' MYC%0'  ' BMPR2%0')  (' MYC%0'  ' PARD6A%0')  (' MYC%0'  ' DAAM1%0')  (' MYC%0'  ' SFRP1_g%0')  (' MYC%0'  ' PPM1A%0')  (' MYC%0'  ' CFL_f%0')  (' MYC%0'  ' PAK1%0')  (' MYC%0'  ' MAP3K11%0')  (' MYC%0'  ' MAP3K4%0')  (' MYC%0'  ' LIMK1%0')  (' MYC%0'  ' ROCK1%0')  (' MYC%0'  ' ITCH%0')  (' MYC%0'  ' ARHGAP24%0')  (' MYC%0'  ' TIAM1%0')  (' MYC%0'  ' RND3%0')  (' MYC%0'  ' MAPK8IP3%0')  (' MYC%0'  ' MXD1%0')  (' MYC%0'  ' PIP3%0')  (' CCND1%0'  ' SRC%0')  (' CCND1%0'  ' CSK%0')  (' CCND1%0'  ' CHUK%0')  (' CCND1%0'  ' RAC_f%0')  (' CCND1%0'  ' DUSP1%0')  (' CCND1%0'  ' TGFBR2%0')  (' CCND1%0'  ' ILR_f%0')  (' CCND1%0'  ' SYK%0')  (' CCND1%0'  ' IRAK1%0')  (' CCND1%0'  ' SHC1%0')  (' CCND1%0'  ' JAK_f%0')  (' CCND1%0'  ' CBPp300_c%0')  (' CCND1%0'  ' SKP2%0')  (' CCND1%0'  ' TP53%0')  (' CCND1%0'  ' SMAD7%0')  (' CCND1%0'  ' SMAD6%0')  (' CCND1%0'  ' DKK_f%0')  (' CCND1%0'  ' FOXO_f%0')  (' CCND1%0'  ' TCF7_f%0')  (' CCND1%0'  ' DKK_g%0')  (' CCND1%0'  ' MYC%0')  (' CCND1%0'  ' EGR1%0')  (' CCND1%0'  ' MMP_f%0')  (' CCND1%0'  ' PTEN_g%0')  (' CCND1%0'  ' RTPK_f%0')  (' CCND1%0'  ' CTNNB1%0')  (' CCND1%0'  'LEF1%0')  (' CCND1%0'  'SFRP1%0')  (' CCND1%0'  'FZD_f%0')  (' CCND1%0'  ' CASP8%0')  (' CCND1%0'  ' REL_f%0')  (' CCND1%0'  ' NFKB_f%0')  (' CCND1%0'  ' DVL_f%0')  (' CCND1%0'  ' LRP_f%0')  (' CCND1%0'  ' BTRC%0')  (' CCND1%0'  ' CK1_f%0')  (' CCND1%0'  ' AXIN1%0')  (' CCND1%0'  ' mTORC2_c%0')  (' CCND1%0'  ' PDPK1%0')  (' CCND1%0'  ' MEK_f%0')  (' CCND1%0'  ' CYCS%0')  (' CCND1%0'  ' CASP9%0')  (' CCND1%0'  ' GSK3_f%0')  (' CCND1%0'  ' IRS1%0')  (' CCND1%0'  ' MDM2%0')  (' CCND1%0'  ' AKT_f%0')  (' CCND1%0'  ' BCL2%0')  (' CCND1%0'  ' RAF_f%0')  (' CCND1%0'  ' mTORC1_c%0')  (' CCND1%0'  ' RHEB%0')  (' CCND1%0'  ' RTPK_g%0')  (' CCND1%0'  ' PTEN%0')  (' CCND1%0'  ' CASP3%0')  (' CCND1%0'  ' PIK3CA%0')  (' CCND1%0'  ' CREBBP%0')  (' CCND1%0'  ' PTPN11%0')  (' CCND1%0'  ' KRAS%0')  (' CCND1%0'  ' MAP2K4%0')  (' CCND1%0'  ' MAP2K7%0')  (' CCND1%0'  ' MAPK14%0')  (' CCND1%0'  ' JNK_f%0')  (' CCND1%0'  ' MAP2K3%0')  (' CCND1%0'  ' ERK_f%0')  (' CCND1%0'  ' LIF%0')  (' CCND1%0'  ' PPP1CA%0')  (' CCND1%0'  ' GAB_f%0')  (' CCND1%0'  ' SOS1%0')  (' CCND1%0'  ' PRKCA%0')  (' CCND1%0'  ' VAV1%0')  (' CCND1%0'  ' PLCG1%0')  (' CCND1%0'  ' PRKCD%0')  (' CCND1%0'  ' RSK_f%0')  (' CCND1%0'  ' S6K_f%0')  (' CCND1%0'  ' PLK1%0')  (' CCND1%0'  ' ILK%0')  (' CCND1%0'  ' SOCS1%0')  (' CCND1%0'  ' DUSP6%0')  (' CCND1%0'  ' STAT3%0')  (' CCND1%0'  ' LIMK2%0')  (' CCND1%0'  ' EP300%0')  (' CCND1%0'  ' STAT1%0')  (' CCND1%0'  ' IKBKB%0')  (' CCND1%0'  ' SRF%0')  (' CCND1%0'  ' PIAS1%0')  (' CCND1%0'  ' TRAF6%0')  (' CCND1%0'  ' SOCS1_g%0')  (' CCND1%0'  ' ISGF3_c%0')  (' CCND1%0'  ' STAT2%0')  (' CCND1%0'  ' CFLAR%0')  (' CCND1%0'  ' SMAD2%0')  (' CCND1%0'  ' MDM2_g%0')  (' CCND1%0'  ' BAX%0')  (' CCND1%0'  ' PRKACA%0')  (' CCND1%0'  ' TGFB1%0')  (' CCND1%0'  ' MAP3K8%0')  (' CCND1%0'  ' TSC_f%0')  (' CCND1%0'  ' SMAD4%0')  (' CCND1%0'  ' BAD%0')  (' CCND1%0'  ' MAP3K5%0')  (' CCND1%0'  ' AKT1S1%0')  (' CCND1%0'  ' SKI%0')  (' CCND1%0'  ' SMAD3%0')  (' CCND1%0'  ' MAPKAPK2%0')  (' CCND1%0'  ' DUSP1_g%0')  (' CCND1%0'  ' MSK_f%0')  (' CCND1%0'  ' GRAP2%0')  (' CCND1%0'  ' TAB_f%0')  (' CCND1%0'  ' ATF2%0')  (' CCND1%0'  ' SMAD5%0')  (' CCND1%0'  ' SMAD1%0')  (' CCND1%0'  ' FOS%0')  (' CCND1%0'  ' JUN%0')  (' CCND1%0'  ' MAP3K7%0')  (' CCND1%0'  ' NLK%0')  (' CCND1%0'  ' SMAD7_g%0')  (' CCND1%0'  ' SMAD6_g%0')  (' CCND1%0'  ' AP1_c%0')  (' CCND1%0'  ' ACVR1%0')  (' CCND1%0'  ' PTPN6%0')  (' CCND1%0'  ' CDC42%0')  (' CCND1%0'  ' GRB2%0')  (' CCND1%0'  ' TGFBR1%0')  (' CCND1%0'  ' SMURF1%0')  (' CCND1%0'  ' SMURF2%0')  (' CCND1%0'  ' RHOA%0')  (' CCND1%0'  ' BMPR2%0')  (' CCND1%0'  ' PARD6A%0')  (' CCND1%0'  ' DAAM1%0')  (' CCND1%0'  ' SFRP1_g%0')  (' CCND1%0'  ' PPM1A%0')  (' CCND1%0'  ' CFL_f%0')  (' CCND1%0'  ' PAK1%0')  (' CCND1%0'  ' MAP3K11%0')  (' CCND1%0'  ' MAP3K4%0')  (' CCND1%0'  ' LIMK1%0')  (' CCND1%0'  ' ROCK1%0')  (' CCND1%0'  ' ITCH%0')  (' CCND1%0'  ' ARHGAP24%0')  (' CCND1%0'  ' TIAM1%0')  (' CCND1%0'  ' RND3%0')  (' CCND1%0'  ' MAPK8IP3%0')  (' CCND1%0'  ' MXD1%0')  (' CCND1%0'  ' PIP3%0')  (' EGR1%0'  ' SRC%0')  (' EGR1%0'  ' CSK%0')  (' EGR1%0'  ' CHUK%0')  (' EGR1%0'  ' RAC_f%0')  (' EGR1%0'  ' DUSP1%0')  (' EGR1%0'  ' TGFBR2%0')  (' EGR1%0'  ' ILR_f%0')  (' EGR1%0'  ' SYK%0')  (' EGR1%0'  ' IRAK1%0')  (' EGR1%0'  ' SHC1%0')  (' EGR1%0'  ' JAK_f%0')  (' EGR1%0'  ' CBPp300_c%0')  (' EGR1%0'  ' SKP2%0')  (' EGR1%0'  ' TP53%0')  (' EGR1%0'  ' SMAD7%0')  (' EGR1%0'  ' SMAD6%0')  (' EGR1%0'  ' DKK_f%0')  (' EGR1%0'  ' FOXO_f%0')  (' EGR1%0'  ' TCF7_f%0')  (' EGR1%0'  ' DKK_g%0')  (' EGR1%0'  ' MYC%0')  (' EGR1%0'  ' CCND1%0')  (' EGR1%0'  ' MMP_f%0')  (' EGR1%0'  ' PTEN_g%0')  (' EGR1%0'  ' RTPK_f%0')  (' EGR1%0'  ' CTNNB1%0')  (' EGR1%0'  'LEF1%0')  (' EGR1%0'  'SFRP1%0')  (' EGR1%0'  'FZD_f%0')  (' EGR1%0'  ' CASP8%0')  (' EGR1%0'  ' REL_f%0')  (' EGR1%0'  ' NFKB_f%0')  (' EGR1%0'  ' DVL_f%0')  (' EGR1%0'  ' LRP_f%0')  (' EGR1%0'  ' BTRC%0')  (' EGR1%0'  ' CK1_f%0')  (' EGR1%0'  ' AXIN1%0')  (' EGR1%0'  ' mTORC2_c%0')  (' EGR1%0'  ' PDPK1%0')  (' EGR1%0'  ' MEK_f%0')  (' EGR1%0'  ' CYCS%0')  (' EGR1%0'  ' CASP9%0')  (' EGR1%0'  ' GSK3_f%0')  (' EGR1%0'  ' IRS1%0')  (' EGR1%0'  ' MDM2%0')  (' EGR1%0'  ' AKT_f%0')  (' EGR1%0'  ' BCL2%0')  (' EGR1%0'  ' RAF_f%0')  (' EGR1%0'  ' mTORC1_c%0')  (' EGR1%0'  ' RHEB%0')  (' EGR1%0'  ' RTPK_g%0')  (' EGR1%0'  ' PTEN%0')  (' EGR1%0'  ' CASP3%0')  (' EGR1%0'  ' PIK3CA%0')  (' EGR1%0'  ' CREBBP%0')  (' EGR1%0'  ' PTPN11%0')  (' EGR1%0'  ' KRAS%0')  (' EGR1%0'  ' MAP2K4%0')  (' EGR1%0'  ' MAP2K7%0')  (' EGR1%0'  ' MAPK14%0')  (' EGR1%0'  ' JNK_f%0')  (' EGR1%0'  ' MAP2K3%0')  (' EGR1%0'  ' ERK_f%0')  (' EGR1%0'  ' LIF%0')  (' EGR1%0'  ' PPP1CA%0')  (' EGR1%0'  ' GAB_f%0')  (' EGR1%0'  ' SOS1%0')  (' EGR1%0'  ' PRKCA%0')  (' EGR1%0'  ' VAV1%0')  (' EGR1%0'  ' PLCG1%0')  (' EGR1%0'  ' PRKCD%0')  (' EGR1%0'  ' RSK_f%0')  (' EGR1%0'  ' S6K_f%0')  (' EGR1%0'  ' PLK1%0')  (' EGR1%0'  ' ILK%0')  (' EGR1%0'  ' SOCS1%0')  (' EGR1%0'  ' DUSP6%0')  (' EGR1%0'  ' STAT3%0')  (' EGR1%0'  ' LIMK2%0')  (' EGR1%0'  ' EP300%0')  (' EGR1%0'  ' STAT1%0')  (' EGR1%0'  ' IKBKB%0')  (' EGR1%0'  ' SRF%0')  (' EGR1%0'  ' PIAS1%0')  (' EGR1%0'  ' TRAF6%0')  (' EGR1%0'  ' SOCS1_g%0')  (' EGR1%0'  ' ISGF3_c%0')  (' EGR1%0'  ' STAT2%0')  (' EGR1%0'  ' CFLAR%0')  (' EGR1%0'  ' SMAD2%0')  (' EGR1%0'  ' MDM2_g%0')  (' EGR1%0'  ' BAX%0')  (' EGR1%0'  ' PRKACA%0')  (' EGR1%0'  ' TGFB1%0')  (' EGR1%0'  ' MAP3K8%0')  (' EGR1%0'  ' TSC_f%0')  (' EGR1%0'  ' SMAD4%0')  (' EGR1%0'  ' BAD%0')  (' EGR1%0'  ' MAP3K5%0')  (' EGR1%0'  ' AKT1S1%0')  (' EGR1%0'  ' SKI%0')  (' EGR1%0'  ' SMAD3%0')  (' EGR1%0'  ' MAPKAPK2%0')  (' EGR1%0'  ' DUSP1_g%0')  (' EGR1%0'  ' MSK_f%0')  (' EGR1%0'  ' GRAP2%0')  (' EGR1%0'  ' TAB_f%0')  (' EGR1%0'  ' ATF2%0')  (' EGR1%0'  ' SMAD5%0')  (' EGR1%0'  ' SMAD1%0')  (' EGR1%0'  ' FOS%0')  (' EGR1%0'  ' JUN%0')  (' EGR1%0'  ' MAP3K7%0')  (' EGR1%0'  ' NLK%0')  (' EGR1%0'  ' SMAD7_g%0')  (' EGR1%0'  ' SMAD6_g%0')  (' EGR1%0'  ' AP1_c%0')  (' EGR1%0'  ' ACVR1%0')  (' EGR1%0'  ' PTPN6%0')  (' EGR1%0'  ' CDC42%0')  (' EGR1%0'  ' GRB2%0')  (' EGR1%0'  ' TGFBR1%0')  (' EGR1%0'  ' SMURF1%0')  (' EGR1%0'  ' SMURF2%0')  (' EGR1%0'  ' RHOA%0')  (' EGR1%0'  ' BMPR2%0')  (' EGR1%0'  ' PARD6A%0')  (' EGR1%0'  ' DAAM1%0')  (' EGR1%0'  ' SFRP1_g%0')  (' EGR1%0'  ' PPM1A%0')  (' EGR1%0'  ' CFL_f%0')  (' EGR1%0'  ' PAK1%0')  (' EGR1%0'  ' MAP3K11%0')  (' EGR1%0'  ' MAP3K4%0')  (' EGR1%0'  ' LIMK1%0')  (' EGR1%0'  ' ROCK1%0')  (' EGR1%0'  ' ITCH%0')  (' EGR1%0'  ' ARHGAP24%0')  (' EGR1%0'  ' TIAM1%0')  (' EGR1%0'  ' RND3%0')  (' EGR1%0'  ' MAPK8IP3%0')  (' EGR1%0'  ' MXD1%0')  (' EGR1%0'  ' PIP3%0')  (' MMP_f%0'  ' SRC%0')  (' MMP_f%0'  ' CSK%0')  (' MMP_f%0'  ' CHUK%0')  (' MMP_f%0'  ' RAC_f%0')  (' MMP_f%0'  ' DUSP1%0')  (' MMP_f%0'  ' TGFBR2%0')  (' MMP_f%0'  ' ILR_f%0')  (' MMP_f%0'  ' SYK%0')  (' MMP_f%0'  ' IRAK1%0')  (' MMP_f%0'  ' SHC1%0')  (' MMP_f%0'  ' JAK_f%0')  (' MMP_f%0'  ' CBPp300_c%0')  (' MMP_f%0'  ' SKP2%0')  (' MMP_f%0'  ' TP53%0')  (' MMP_f%0'  ' SMAD7%0')  (' MMP_f%0'  ' SMAD6%0')  (' MMP_f%0'  ' DKK_f%0')  (' MMP_f%0'  ' FOXO_f%0')  (' MMP_f%0'  ' TCF7_f%0')  (' MMP_f%0'  ' DKK_g%0')  (' MMP_f%0'  ' MYC%0')  (' MMP_f%0'  ' CCND1%0')  (' MMP_f%0'  ' EGR1%0')  (' MMP_f%0'  ' PTEN_g%0')  (' MMP_f%0'  ' RTPK_f%0')  (' MMP_f%0'  ' CTNNB1%0')  (' MMP_f%0'  'LEF1%0')  (' MMP_f%0'  'SFRP1%0')  (' MMP_f%0'  'FZD_f%0')  (' MMP_f%0'  ' CASP8%0')  (' MMP_f%0'  ' REL_f%0')  (' MMP_f%0'  ' NFKB_f%0')  (' MMP_f%0'  ' DVL_f%0')  (' MMP_f%0'  ' LRP_f%0')  (' MMP_f%0'  ' BTRC%0')  (' MMP_f%0'  ' CK1_f%0')  (' MMP_f%0'  ' AXIN1%0')  (' MMP_f%0'  ' mTORC2_c%0')  (' MMP_f%0'  ' PDPK1%0')  (' MMP_f%0'  ' MEK_f%0')  (' MMP_f%0'  ' CYCS%0')  (' MMP_f%0'  ' CASP9%0')  (' MMP_f%0'  ' GSK3_f%0')  (' MMP_f%0'  ' IRS1%0')  (' MMP_f%0'  ' MDM2%0')  (' MMP_f%0'  ' AKT_f%0')  (' MMP_f%0'  ' BCL2%0')  (' MMP_f%0'  ' RAF_f%0')  (' MMP_f%0'  ' mTORC1_c%0')  (' MMP_f%0'  ' RHEB%0')  (' MMP_f%0'  ' RTPK_g%0')  (' MMP_f%0'  ' PTEN%0')  (' MMP_f%0'  ' CASP3%0')  (' MMP_f%0'  ' PIK3CA%0')  (' MMP_f%0'  ' CREBBP%0')  (' MMP_f%0'  ' PTPN11%0')  (' MMP_f%0'  ' KRAS%0')  (' MMP_f%0'  ' MAP2K4%0')  (' MMP_f%0'  ' MAP2K7%0')  (' MMP_f%0'  ' MAPK14%0')  (' MMP_f%0'  ' JNK_f%0')  (' MMP_f%0'  ' MAP2K3%0')  (' MMP_f%0'  ' ERK_f%0')  (' MMP_f%0'  ' LIF%0')  (' MMP_f%0'  ' PPP1CA%0')  (' MMP_f%0'  ' GAB_f%0')  (' MMP_f%0'  ' SOS1%0')  (' MMP_f%0'  ' PRKCA%0')  (' MMP_f%0'  ' VAV1%0')  (' MMP_f%0'  ' PLCG1%0')  (' MMP_f%0'  ' PRKCD%0')  (' MMP_f%0'  ' RSK_f%0')  (' MMP_f%0'  ' S6K_f%0')  (' MMP_f%0'  ' PLK1%0')  (' MMP_f%0'  ' ILK%0')  (' MMP_f%0'  ' SOCS1%0')  (' MMP_f%0'  ' DUSP6%0')  (' MMP_f%0'  ' STAT3%0')  (' MMP_f%0'  ' LIMK2%0')  (' MMP_f%0'  ' EP300%0')  (' MMP_f%0'  ' STAT1%0')  (' MMP_f%0'  ' IKBKB%0')  (' MMP_f%0'  ' SRF%0')  (' MMP_f%0'  ' PIAS1%0')  (' MMP_f%0'  ' TRAF6%0')  (' MMP_f%0'  ' SOCS1_g%0')  (' MMP_f%0'  ' ISGF3_c%0')  (' MMP_f%0'  ' STAT2%0')  (' MMP_f%0'  ' CFLAR%0')  (' MMP_f%0'  ' SMAD2%0')  (' MMP_f%0'  ' MDM2_g%0')  (' MMP_f%0'  ' BAX%0')  (' MMP_f%0'  ' PRKACA%0')  (' MMP_f%0'  ' TGFB1%0')  (' MMP_f%0'  ' MAP3K8%0')  (' MMP_f%0'  ' TSC_f%0')  (' MMP_f%0'  ' SMAD4%0')  (' MMP_f%0'  ' BAD%0')  (' MMP_f%0'  ' MAP3K5%0')  (' MMP_f%0'  ' AKT1S1%0')  (' MMP_f%0'  ' SKI%0')  (' MMP_f%0'  ' SMAD3%0')  (' MMP_f%0'  ' MAPKAPK2%0')  (' MMP_f%0'  ' DUSP1_g%0')  (' MMP_f%0'  ' MSK_f%0')  (' MMP_f%0'  ' GRAP2%0')  (' MMP_f%0'  ' TAB_f%0')  (' MMP_f%0'  ' ATF2%0')  (' MMP_f%0'  ' SMAD5%0')  (' MMP_f%0'  ' SMAD1%0')  (' MMP_f%0'  ' FOS%0')  (' MMP_f%0'  ' JUN%0')  (' MMP_f%0'  ' MAP3K7%0')  (' MMP_f%0'  ' NLK%0')  (' MMP_f%0'  ' SMAD7_g%0')  (' MMP_f%0'  ' SMAD6_g%0')  (' MMP_f%0'  ' AP1_c%0')  (' MMP_f%0'  ' ACVR1%0')  (' MMP_f%0'  ' PTPN6%0')  (' MMP_f%0'  ' CDC42%0')  (' MMP_f%0'  ' GRB2%0')  (' MMP_f%0'  ' TGFBR1%0')  (' MMP_f%0'  ' SMURF1%0')  (' MMP_f%0'  ' SMURF2%0')  (' MMP_f%0'  ' RHOA%0')  (' MMP_f%0'  ' BMPR2%0')  (' MMP_f%0'  ' PARD6A%0')  (' MMP_f%0'  ' DAAM1%0')  (' MMP_f%0'  ' SFRP1_g%0')  (' MMP_f%0'  ' PPM1A%0')  (' MMP_f%0'  ' CFL_f%0')  (' MMP_f%0'  ' PAK1%0')  (' MMP_f%0'  ' MAP3K11%0')  (' MMP_f%0'  ' MAP3K4%0')  (' MMP_f%0'  ' LIMK1%0')  (' MMP_f%0'  ' ROCK1%0')  (' MMP_f%0'  ' ITCH%0')  (' MMP_f%0'  ' ARHGAP24%0')  (' MMP_f%0'  ' TIAM1%0')  (' MMP_f%0'  ' RND3%0')  (' MMP_f%0'  ' MAPK8IP3%0')  (' MMP_f%0'  ' MXD1%0')  (' MMP_f%0'  ' PIP3%0')  (' PTEN_g%0'  ' SRC%0')  (' PTEN_g%0'  ' CSK%0')  (' PTEN_g%0'  ' CHUK%0')  (' PTEN_g%0'  ' RAC_f%0')  (' PTEN_g%0'  ' DUSP1%0')  (' PTEN_g%0'  ' TGFBR2%0')  (' PTEN_g%0'  ' ILR_f%0')  (' PTEN_g%0'  ' SYK%0')  (' PTEN_g%0'  ' IRAK1%0')  (' PTEN_g%0'  ' SHC1%0')  (' PTEN_g%0'  ' JAK_f%0')  (' PTEN_g%0'  ' CBPp300_c%0')  (' PTEN_g%0'  ' SKP2%0')  (' PTEN_g%0'  ' TP53%0')  (' PTEN_g%0'  ' SMAD7%0')  (' PTEN_g%0'  ' SMAD6%0')  (' PTEN_g%0'  ' DKK_f%0')  (' PTEN_g%0'  ' FOXO_f%0')  (' PTEN_g%0'  ' TCF7_f%0')  (' PTEN_g%0'  ' DKK_g%0')  (' PTEN_g%0'  ' MYC%0')  (' PTEN_g%0'  ' CCND1%0')  (' PTEN_g%0'  ' EGR1%0')  (' PTEN_g%0'  ' MMP_f%0')  (' PTEN_g%0'  ' RTPK_f%0')  (' PTEN_g%0'  ' CTNNB1%0')  (' PTEN_g%0'  'LEF1%0')  (' PTEN_g%0'  'SFRP1%0')  (' PTEN_g%0'  'FZD_f%0')  (' PTEN_g%0'  ' CASP8%0')  (' PTEN_g%0'  ' REL_f%0')  (' PTEN_g%0'  ' NFKB_f%0')  (' PTEN_g%0'  ' DVL_f%0')  (' PTEN_g%0'  ' LRP_f%0')  (' PTEN_g%0'  ' BTRC%0')  (' PTEN_g%0'  ' CK1_f%0')  (' PTEN_g%0'  ' AXIN1%0')  (' PTEN_g%0'  ' mTORC2_c%0')  (' PTEN_g%0'  ' PDPK1%0')  (' PTEN_g%0'  ' MEK_f%0')  (' PTEN_g%0'  ' CYCS%0')  (' PTEN_g%0'  ' CASP9%0')  (' PTEN_g%0'  ' GSK3_f%0')  (' PTEN_g%0'  ' IRS1%0')  (' PTEN_g%0'  ' MDM2%0')  (' PTEN_g%0'  ' AKT_f%0')  (' PTEN_g%0'  ' BCL2%0')  (' PTEN_g%0'  ' RAF_f%0')  (' PTEN_g%0'  ' mTORC1_c%0')  (' PTEN_g%0'  ' RHEB%0')  (' PTEN_g%0'  ' RTPK_g%0')  (' PTEN_g%0'  ' PTEN%0')  (' PTEN_g%0'  ' CASP3%0')  (' PTEN_g%0'  ' PIK3CA%0')  (' PTEN_g%0'  ' CREBBP%0')  (' PTEN_g%0'  ' PTPN11%0')  (' PTEN_g%0'  ' KRAS%0')  (' PTEN_g%0'  ' MAP2K4%0')  (' PTEN_g%0'  ' MAP2K7%0')  (' PTEN_g%0'  ' MAPK14%0')  (' PTEN_g%0'  ' JNK_f%0')  (' PTEN_g%0'  ' MAP2K3%0')  (' PTEN_g%0'  ' ERK_f%0')  (' PTEN_g%0'  ' LIF%0')  (' PTEN_g%0'  ' PPP1CA%0')  (' PTEN_g%0'  ' GAB_f%0')  (' PTEN_g%0'  ' SOS1%0')  (' PTEN_g%0'  ' PRKCA%0')  (' PTEN_g%0'  ' VAV1%0')  (' PTEN_g%0'  ' PLCG1%0')  (' PTEN_g%0'  ' PRKCD%0')  (' PTEN_g%0'  ' RSK_f%0')  (' PTEN_g%0'  ' S6K_f%0')  (' PTEN_g%0'  ' PLK1%0')  (' PTEN_g%0'  ' ILK%0')  (' PTEN_g%0'  ' SOCS1%0')  (' PTEN_g%0'  ' DUSP6%0')  (' PTEN_g%0'  ' STAT3%0')  (' PTEN_g%0'  ' LIMK2%0')  (' PTEN_g%0'  ' EP300%0')  (' PTEN_g%0'  ' STAT1%0')  (' PTEN_g%0'  ' IKBKB%0')  (' PTEN_g%0'  ' SRF%0')  (' PTEN_g%0'  ' PIAS1%0')  (' PTEN_g%0'  ' TRAF6%0')  (' PTEN_g%0'  ' SOCS1_g%0')  (' PTEN_g%0'  ' ISGF3_c%0')  (' PTEN_g%0'  ' STAT2%0')  (' PTEN_g%0'  ' CFLAR%0')  (' PTEN_g%0'  ' SMAD2%0')  (' PTEN_g%0'  ' MDM2_g%0')  (' PTEN_g%0'  ' BAX%0')  (' PTEN_g%0'  ' PRKACA%0')  (' PTEN_g%0'  ' TGFB1%0')  (' PTEN_g%0'  ' MAP3K8%0')  (' PTEN_g%0'  ' TSC_f%0')  (' PTEN_g%0'  ' SMAD4%0')  (' PTEN_g%0'  ' BAD%0')  (' PTEN_g%0'  ' MAP3K5%0')  (' PTEN_g%0'  ' AKT1S1%0')  (' PTEN_g%0'  ' SKI%0')  (' PTEN_g%0'  ' SMAD3%0')  (' PTEN_g%0'  ' MAPKAPK2%0')  (' PTEN_g%0'  ' DUSP1_g%0')  (' PTEN_g%0'  ' MSK_f%0')  (' PTEN_g%0'  ' GRAP2%0')  (' PTEN_g%0'  ' TAB_f%0')  (' PTEN_g%0'  ' ATF2%0')  (' PTEN_g%0'  ' SMAD5%0')  (' PTEN_g%0'  ' SMAD1%0')  (' PTEN_g%0'  ' FOS%0')  (' PTEN_g%0'  ' JUN%0')  (' PTEN_g%0'  ' MAP3K7%0')  (' PTEN_g%0'  ' NLK%0')  (' PTEN_g%0'  ' SMAD7_g%0')  (' PTEN_g%0'  ' SMAD6_g%0')  (' PTEN_g%0'  ' AP1_c%0')  (' PTEN_g%0'  ' ACVR1%0')  (' PTEN_g%0'  ' PTPN6%0')  (' PTEN_g%0'  ' CDC42%0')  (' PTEN_g%0'  ' GRB2%0')  (' PTEN_g%0'  ' TGFBR1%0')  (' PTEN_g%0'  ' SMURF1%0')  (' PTEN_g%0'  ' SMURF2%0')  (' PTEN_g%0'  ' RHOA%0')  (' PTEN_g%0'  ' BMPR2%0')  (' PTEN_g%0'  ' PARD6A%0')  (' PTEN_g%0'  ' DAAM1%0')  (' PTEN_g%0'  ' SFRP1_g%0')  (' PTEN_g%0'  ' PPM1A%0')  (' PTEN_g%0'  ' CFL_f%0')  (' PTEN_g%0'  ' PAK1%0')  (' PTEN_g%0'  ' MAP3K11%0')  (' PTEN_g%0'  ' MAP3K4%0')  (' PTEN_g%0'  ' LIMK1%0')  (' PTEN_g%0'  ' ROCK1%0')  (' PTEN_g%0'  ' ITCH%0')  (' PTEN_g%0'  ' ARHGAP24%0')  (' PTEN_g%0'  ' TIAM1%0')  (' PTEN_g%0'  ' RND3%0')  (' PTEN_g%0'  ' MAPK8IP3%0')  (' PTEN_g%0'  ' MXD1%0')  (' PTEN_g%0'  ' PIP3%0')  (' RTPK_f%0'  ' SRC%0')  (' RTPK_f%0'  ' CSK%0')  (' RTPK_f%0'  ' CHUK%0')  (' RTPK_f%0'  ' RAC_f%0')  (' RTPK_f%0'  ' DUSP1%0')  (' RTPK_f%0'  ' TGFBR2%0')  (' RTPK_f%0'  ' ILR_f%0')  (' RTPK_f%0'  ' SYK%0')  (' RTPK_f%0'  ' IRAK1%0')  (' RTPK_f%0'  ' SHC1%0')  (' RTPK_f%0'  ' JAK_f%0')  (' RTPK_f%0'  ' CBPp300_c%0')  (' RTPK_f%0'  ' SKP2%0')  (' RTPK_f%0'  ' TP53%0')  (' RTPK_f%0'  ' SMAD7%0')  (' RTPK_f%0'  ' SMAD6%0')  (' RTPK_f%0'  ' DKK_f%0')  (' RTPK_f%0'  ' FOXO_f%0')  (' RTPK_f%0'  ' TCF7_f%0')  (' RTPK_f%0'  ' DKK_g%0')  (' RTPK_f%0'  ' MYC%0')  (' RTPK_f%0'  ' CCND1%0')  (' RTPK_f%0'  ' EGR1%0')  (' RTPK_f%0'  ' MMP_f%0')  (' RTPK_f%0'  ' PTEN_g%0')  (' RTPK_f%0'  ' CTNNB1%0')  (' RTPK_f%0'  'LEF1%0')  (' RTPK_f%0'  'SFRP1%0')  (' RTPK_f%0'  'FZD_f%0')  (' RTPK_f%0'  ' CASP8%0')  (' RTPK_f%0'  ' REL_f%0')  (' RTPK_f%0'  ' NFKB_f%0')  (' RTPK_f%0'  ' DVL_f%0')  (' RTPK_f%0'  ' LRP_f%0')  (' RTPK_f%0'  ' BTRC%0')  (' RTPK_f%0'  ' CK1_f%0')  (' RTPK_f%0'  ' AXIN1%0')  (' RTPK_f%0'  ' mTORC2_c%0')  (' RTPK_f%0'  ' PDPK1%0')  (' RTPK_f%0'  ' MEK_f%0')  (' RTPK_f%0'  ' CYCS%0')  (' RTPK_f%0'  ' CASP9%0')  (' RTPK_f%0'  ' GSK3_f%0')  (' RTPK_f%0'  ' IRS1%0')  (' RTPK_f%0'  ' MDM2%0')  (' RTPK_f%0'  ' AKT_f%0')  (' RTPK_f%0'  ' BCL2%0')  (' RTPK_f%0'  ' RAF_f%0')  (' RTPK_f%0'  ' mTORC1_c%0')  (' RTPK_f%0'  ' RHEB%0')  (' RTPK_f%0'  ' RTPK_g%0')  (' RTPK_f%0'  ' PTEN%0')  (' RTPK_f%0'  ' CASP3%0')  (' RTPK_f%0'  ' PIK3CA%0')  (' RTPK_f%0'  ' CREBBP%0')  (' RTPK_f%0'  ' PTPN11%0')  (' RTPK_f%0'  ' KRAS%0')  (' RTPK_f%0'  ' MAP2K4%0')  (' RTPK_f%0'  ' MAP2K7%0')  (' RTPK_f%0'  ' MAPK14%0')  (' RTPK_f%0'  ' JNK_f%0')  (' RTPK_f%0'  ' MAP2K3%0')  (' RTPK_f%0'  ' ERK_f%0')  (' RTPK_f%0'  ' LIF%0')  (' RTPK_f%0'  ' PPP1CA%0')  (' RTPK_f%0'  ' GAB_f%0')  (' RTPK_f%0'  ' SOS1%0')  (' RTPK_f%0'  ' PRKCA%0')  (' RTPK_f%0'  ' VAV1%0')  (' RTPK_f%0'  ' PLCG1%0')  (' RTPK_f%0'  ' PRKCD%0')  (' RTPK_f%0'  ' RSK_f%0')  (' RTPK_f%0'  ' S6K_f%0')  (' RTPK_f%0'  ' PLK1%0')  (' RTPK_f%0'  ' ILK%0')  (' RTPK_f%0'  ' SOCS1%0')  (' RTPK_f%0'  ' DUSP6%0')  (' RTPK_f%0'  ' STAT3%0')  (' RTPK_f%0'  ' LIMK2%0')  (' RTPK_f%0'  ' EP300%0')  (' RTPK_f%0'  ' STAT1%0')  (' RTPK_f%0'  ' IKBKB%0')  (' RTPK_f%0'  ' SRF%0')  (' RTPK_f%0'  ' PIAS1%0')  (' RTPK_f%0'  ' TRAF6%0')  (' RTPK_f%0'  ' SOCS1_g%0')  (' RTPK_f%0'  ' ISGF3_c%0')  (' RTPK_f%0'  ' STAT2%0')  (' RTPK_f%0'  ' CFLAR%0')  (' RTPK_f%0'  ' SMAD2%0')  (' RTPK_f%0'  ' MDM2_g%0')  (' RTPK_f%0'  ' BAX%0')  (' RTPK_f%0'  ' PRKACA%0')  (' RTPK_f%0'  ' TGFB1%0')  (' RTPK_f%0'  ' MAP3K8%0')  (' RTPK_f%0'  ' TSC_f%0')  (' RTPK_f%0'  ' SMAD4%0')  (' RTPK_f%0'  ' BAD%0')  (' RTPK_f%0'  ' MAP3K5%0')  (' RTPK_f%0'  ' AKT1S1%0')  (' RTPK_f%0'  ' SKI%0')  (' RTPK_f%0'  ' SMAD3%0')  (' RTPK_f%0'  ' MAPKAPK2%0')  (' RTPK_f%0'  ' DUSP1_g%0')  (' RTPK_f%0'  ' MSK_f%0')  (' RTPK_f%0'  ' GRAP2%0')  (' RTPK_f%0'  ' TAB_f%0')  (' RTPK_f%0'  ' ATF2%0')  (' RTPK_f%0'  ' SMAD5%0')  (' RTPK_f%0'  ' SMAD1%0')  (' RTPK_f%0'  ' FOS%0')  (' RTPK_f%0'  ' JUN%0')  (' RTPK_f%0'  ' MAP3K7%0')  (' RTPK_f%0'  ' NLK%0')  (' RTPK_f%0'  ' SMAD7_g%0')  (' RTPK_f%0'  ' SMAD6_g%0')  (' RTPK_f%0'  ' AP1_c%0')  (' RTPK_f%0'  ' ACVR1%0')  (' RTPK_f%0'  ' PTPN6%0')  (' RTPK_f%0'  ' CDC42%0')  (' RTPK_f%0'  ' GRB2%0')  (' RTPK_f%0'  ' TGFBR1%0')  (' RTPK_f%0'  ' SMURF1%0')  (' RTPK_f%0'  ' SMURF2%0')  (' RTPK_f%0'  ' RHOA%0')  (' RTPK_f%0'  ' BMPR2%0')  (' RTPK_f%0'  ' PARD6A%0')  (' RTPK_f%0'  ' DAAM1%0')  (' RTPK_f%0'  ' SFRP1_g%0')  (' RTPK_f%0'  ' PPM1A%0')  (' RTPK_f%0'  ' CFL_f%0')  (' RTPK_f%0'  ' PAK1%0')  (' RTPK_f%0'  ' MAP3K11%0')  (' RTPK_f%0'  ' MAP3K4%0')  (' RTPK_f%0'  ' LIMK1%0')  (' RTPK_f%0'  ' ROCK1%0')  (' RTPK_f%0'  ' ITCH%0')  (' RTPK_f%0'  ' ARHGAP24%0')  (' RTPK_f%0'  ' TIAM1%0')  (' RTPK_f%0'  ' RND3%0')  (' RTPK_f%0'  ' MAPK8IP3%0')  (' RTPK_f%0'  ' MXD1%0')  (' RTPK_f%0'  ' PIP3%0')  (' CTNNB1%0'  ' SRC%0')  (' CTNNB1%0'  ' CSK%0')  (' CTNNB1%0'  ' CHUK%0')  (' CTNNB1%0'  ' RAC_f%0')  (' CTNNB1%0'  ' DUSP1%0')  (' CTNNB1%0'  ' TGFBR2%0')  (' CTNNB1%0'  ' ILR_f%0')  (' CTNNB1%0'  ' SYK%0')  (' CTNNB1%0'  ' IRAK1%0')  (' CTNNB1%0'  ' SHC1%0')  (' CTNNB1%0'  ' JAK_f%0')  (' CTNNB1%0'  ' CBPp300_c%0')  (' CTNNB1%0'  ' SKP2%0')  (' CTNNB1%0'  ' TP53%0')  (' CTNNB1%0'  ' SMAD7%0')  (' CTNNB1%0'  ' SMAD6%0')  (' CTNNB1%0'  ' DKK_f%0')  (' CTNNB1%0'  ' FOXO_f%0')  (' CTNNB1%0'  ' TCF7_f%0')  (' CTNNB1%0'  ' DKK_g%0')  (' CTNNB1%0'  ' MYC%0')  (' CTNNB1%0'  ' CCND1%0')  (' CTNNB1%0'  ' EGR1%0')  (' CTNNB1%0'  ' MMP_f%0')  (' CTNNB1%0'  ' PTEN_g%0')  (' CTNNB1%0'  ' RTPK_f%0')  (' CTNNB1%0'  'LEF1%0')  (' CTNNB1%0'  'SFRP1%0')  (' CTNNB1%0'  'FZD_f%0')  (' CTNNB1%0'  ' CASP8%0')  (' CTNNB1%0'  ' REL_f%0')  (' CTNNB1%0'  ' NFKB_f%0')  (' CTNNB1%0'  ' DVL_f%0')  (' CTNNB1%0'  ' LRP_f%0')  (' CTNNB1%0'  ' BTRC%0')  (' CTNNB1%0'  ' CK1_f%0')  (' CTNNB1%0'  ' AXIN1%0')  (' CTNNB1%0'  ' mTORC2_c%0')  (' CTNNB1%0'  ' PDPK1%0')  (' CTNNB1%0'  ' MEK_f%0')  (' CTNNB1%0'  ' CYCS%0')  (' CTNNB1%0'  ' CASP9%0')  (' CTNNB1%0'  ' GSK3_f%0')  (' CTNNB1%0'  ' IRS1%0')  (' CTNNB1%0'  ' MDM2%0')  (' CTNNB1%0'  ' AKT_f%0')  (' CTNNB1%0'  ' BCL2%0')  (' CTNNB1%0'  ' RAF_f%0')  (' CTNNB1%0'  ' mTORC1_c%0')  (' CTNNB1%0'  ' RHEB%0')  (' CTNNB1%0'  ' RTPK_g%0')  (' CTNNB1%0'  ' PTEN%0')  (' CTNNB1%0'  ' CASP3%0')  (' CTNNB1%0'  ' PIK3CA%0')  (' CTNNB1%0'  ' CREBBP%0')  (' CTNNB1%0'  ' PTPN11%0')  (' CTNNB1%0'  ' KRAS%0')  (' CTNNB1%0'  ' MAP2K4%0')  (' CTNNB1%0'  ' MAP2K7%0')  (' CTNNB1%0'  ' MAPK14%0')  (' CTNNB1%0'  ' JNK_f%0')  (' CTNNB1%0'  ' MAP2K3%0')  (' CTNNB1%0'  ' ERK_f%0')  (' CTNNB1%0'  ' LIF%0')  (' CTNNB1%0'  ' PPP1CA%0')  (' CTNNB1%0'  ' GAB_f%0')  (' CTNNB1%0'  ' SOS1%0')  (' CTNNB1%0'  ' PRKCA%0')  (' CTNNB1%0'  ' VAV1%0')  (' CTNNB1%0'  ' PLCG1%0')  (' CTNNB1%0'  ' PRKCD%0')  (' CTNNB1%0'  ' RSK_f%0')  (' CTNNB1%0'  ' S6K_f%0')  (' CTNNB1%0'  ' PLK1%0')  (' CTNNB1%0'  ' ILK%0')  (' CTNNB1%0'  ' SOCS1%0')  (' CTNNB1%0'  ' DUSP6%0')  (' CTNNB1%0'  ' STAT3%0')  (' CTNNB1%0'  ' LIMK2%0')  (' CTNNB1%0'  ' EP300%0')  (' CTNNB1%0'  ' STAT1%0')  (' CTNNB1%0'  ' IKBKB%0')  (' CTNNB1%0'  ' SRF%0')  (' CTNNB1%0'  ' PIAS1%0')  (' CTNNB1%0'  ' TRAF6%0')  (' CTNNB1%0'  ' SOCS1_g%0')  (' CTNNB1%0'  ' ISGF3_c%0')  (' CTNNB1%0'  ' STAT2%0')  (' CTNNB1%0'  ' CFLAR%0')  (' CTNNB1%0'  ' SMAD2%0')  (' CTNNB1%0'  ' MDM2_g%0')  (' CTNNB1%0'  ' BAX%0')  (' CTNNB1%0'  ' PRKACA%0')  (' CTNNB1%0'  ' TGFB1%0')  (' CTNNB1%0'  ' MAP3K8%0')  (' CTNNB1%0'  ' TSC_f%0')  (' CTNNB1%0'  ' SMAD4%0')  (' CTNNB1%0'  ' BAD%0')  (' CTNNB1%0'  ' MAP3K5%0')  (' CTNNB1%0'  ' AKT1S1%0')  (' CTNNB1%0'  ' SKI%0')  (' CTNNB1%0'  ' SMAD3%0')  (' CTNNB1%0'  ' MAPKAPK2%0')  (' CTNNB1%0'  ' DUSP1_g%0')  (' CTNNB1%0'  ' MSK_f%0')  (' CTNNB1%0'  ' GRAP2%0')  (' CTNNB1%0'  ' TAB_f%0')  (' CTNNB1%0'  ' ATF2%0')  (' CTNNB1%0'  ' SMAD5%0')  (' CTNNB1%0'  ' SMAD1%0')  (' CTNNB1%0'  ' FOS%0')  (' CTNNB1%0'  ' JUN%0')  (' CTNNB1%0'  ' MAP3K7%0')  (' CTNNB1%0'  ' NLK%0')  (' CTNNB1%0'  ' SMAD7_g%0')  (' CTNNB1%0'  ' SMAD6_g%0')  (' CTNNB1%0'  ' AP1_c%0')  (' CTNNB1%0'  ' ACVR1%0')  (' CTNNB1%0'  ' PTPN6%0')  (' CTNNB1%0'  ' CDC42%0')  (' CTNNB1%0'  ' GRB2%0')  (' CTNNB1%0'  ' TGFBR1%0')  (' CTNNB1%0'  ' SMURF1%0')  (' CTNNB1%0'  ' SMURF2%0')  (' CTNNB1%0'  ' RHOA%0')  (' CTNNB1%0'  ' BMPR2%0')  (' CTNNB1%0'  ' PARD6A%0')  (' CTNNB1%0'  ' DAAM1%0')  (' CTNNB1%0'  ' SFRP1_g%0')  (' CTNNB1%0'  ' PPM1A%0')  (' CTNNB1%0'  ' CFL_f%0')  (' CTNNB1%0'  ' PAK1%0')  (' CTNNB1%0'  ' MAP3K11%0')  (' CTNNB1%0'  ' MAP3K4%0')  (' CTNNB1%0'  ' LIMK1%0')  (' CTNNB1%0'  ' ROCK1%0')  (' CTNNB1%0'  ' ITCH%0')  (' CTNNB1%0'  ' ARHGAP24%0')  (' CTNNB1%0'  ' TIAM1%0')  (' CTNNB1%0'  ' RND3%0')  (' CTNNB1%0'  ' MAPK8IP3%0')  (' CTNNB1%0'  ' MXD1%0')  (' CTNNB1%0'  ' PIP3%0')  ('LEF1%0'  ' SRC%0')  ('LEF1%0'  ' CSK%0')  ('LEF1%0'  ' CHUK%0')  ('LEF1%0'  ' RAC_f%0')  ('LEF1%0'  ' DUSP1%0')  ('LEF1%0'  ' TGFBR2%0')  ('LEF1%0'  ' ILR_f%0')  ('LEF1%0'  ' SYK%0')  ('LEF1%0'  ' IRAK1%0')  ('LEF1%0'  ' SHC1%0')  ('LEF1%0'  ' JAK_f%0')  ('LEF1%0'  ' CBPp300_c%0')  ('LEF1%0'  ' SKP2%0')  ('LEF1%0'  ' TP53%0')  ('LEF1%0'  ' SMAD7%0')  ('LEF1%0'  ' SMAD6%0')  ('LEF1%0'  ' DKK_f%0')  ('LEF1%0'  ' FOXO_f%0')  ('LEF1%0'  ' TCF7_f%0')  ('LEF1%0'  ' DKK_g%0')  ('LEF1%0'  ' MYC%0')  ('LEF1%0'  ' CCND1%0')  ('LEF1%0'  ' EGR1%0')  ('LEF1%0'  ' MMP_f%0')  ('LEF1%0'  ' PTEN_g%0')  ('LEF1%0'  ' RTPK_f%0')  ('LEF1%0'  ' CTNNB1%0')  ('LEF1%0'  'SFRP1%0')  ('LEF1%0'  'FZD_f%0')  ('LEF1%0'  ' CASP8%0')  ('LEF1%0'  ' REL_f%0')  ('LEF1%0'  ' NFKB_f%0')  ('LEF1%0'  ' DVL_f%0')  ('LEF1%0'  ' LRP_f%0')  ('LEF1%0'  ' BTRC%0')  ('LEF1%0'  ' CK1_f%0')  ('LEF1%0'  ' AXIN1%0')  ('LEF1%0'  ' mTORC2_c%0')  ('LEF1%0'  ' PDPK1%0')  ('LEF1%0'  ' MEK_f%0')  ('LEF1%0'  ' CYCS%0')  ('LEF1%0'  ' CASP9%0')  ('LEF1%0'  ' GSK3_f%0')  ('LEF1%0'  ' IRS1%0')  ('LEF1%0'  ' MDM2%0')  ('LEF1%0'  ' AKT_f%0')  ('LEF1%0'  ' BCL2%0')  ('LEF1%0'  ' RAF_f%0')  ('LEF1%0'  ' mTORC1_c%0')  ('LEF1%0'  ' RHEB%0')  ('LEF1%0'  ' RTPK_g%0')  ('LEF1%0'  ' PTEN%0')  ('LEF1%0'  ' CASP3%0')  ('LEF1%0'  ' PIK3CA%0')  ('LEF1%0'  ' CREBBP%0')  ('LEF1%0'  ' PTPN11%0')  ('LEF1%0'  ' KRAS%0')  ('LEF1%0'  ' MAP2K4%0')  ('LEF1%0'  ' MAP2K7%0')  ('LEF1%0'  ' MAPK14%0')  ('LEF1%0'  ' JNK_f%0')  ('LEF1%0'  ' MAP2K3%0')  ('LEF1%0'  ' ERK_f%0')  ('LEF1%0'  ' LIF%0')  ('LEF1%0'  ' PPP1CA%0')  ('LEF1%0'  ' GAB_f%0')  ('LEF1%0'  ' SOS1%0')  ('LEF1%0'  ' PRKCA%0')  ('LEF1%0'  ' VAV1%0')  ('LEF1%0'  ' PLCG1%0')  ('LEF1%0'  ' PRKCD%0')  ('LEF1%0'  ' RSK_f%0')  ('LEF1%0'  ' S6K_f%0')  ('LEF1%0'  ' PLK1%0')  ('LEF1%0'  ' ILK%0')  ('LEF1%0'  ' SOCS1%0')  ('LEF1%0'  ' DUSP6%0')  ('LEF1%0'  ' STAT3%0')  ('LEF1%0'  ' LIMK2%0')  ('LEF1%0'  ' EP300%0')  ('LEF1%0'  ' STAT1%0')  ('LEF1%0'  ' IKBKB%0')  ('LEF1%0'  ' SRF%0')  ('LEF1%0'  ' PIAS1%0')  ('LEF1%0'  ' TRAF6%0')  ('LEF1%0'  ' SOCS1_g%0')  ('LEF1%0'  ' ISGF3_c%0')  ('LEF1%0'  ' STAT2%0')  ('LEF1%0'  ' CFLAR%0')  ('LEF1%0'  ' SMAD2%0')  ('LEF1%0'  ' MDM2_g%0')  ('LEF1%0'  ' BAX%0')  ('LEF1%0'  ' PRKACA%0')  ('LEF1%0'  ' TGFB1%0')  ('LEF1%0'  ' MAP3K8%0')  ('LEF1%0'  ' TSC_f%0')  ('LEF1%0'  ' SMAD4%0')  ('LEF1%0'  ' BAD%0')  ('LEF1%0'  ' MAP3K5%0')  ('LEF1%0'  ' AKT1S1%0')  ('LEF1%0'  ' SKI%0')  ('LEF1%0'  ' SMAD3%0')  ('LEF1%0'  ' MAPKAPK2%0')  ('LEF1%0'  ' DUSP1_g%0')  ('LEF1%0'  ' MSK_f%0')  ('LEF1%0'  ' GRAP2%0')  ('LEF1%0'  ' TAB_f%0')  ('LEF1%0'  ' ATF2%0')  ('LEF1%0'  ' SMAD5%0')  ('LEF1%0'  ' SMAD1%0')  ('LEF1%0'  ' FOS%0')  ('LEF1%0'  ' JUN%0')  ('LEF1%0'  ' MAP3K7%0')  ('LEF1%0'  ' NLK%0')  ('LEF1%0'  ' SMAD7_g%0')  ('LEF1%0'  ' SMAD6_g%0')  ('LEF1%0'  ' AP1_c%0')  ('LEF1%0'  ' ACVR1%0')  ('LEF1%0'  ' PTPN6%0')  ('LEF1%0'  ' CDC42%0')  ('LEF1%0'  ' GRB2%0')  ('LEF1%0'  ' TGFBR1%0')  ('LEF1%0'  ' SMURF1%0')  ('LEF1%0'  ' SMURF2%0')  ('LEF1%0'  ' RHOA%0')  ('LEF1%0'  ' BMPR2%0')  ('LEF1%0'  ' PARD6A%0')  ('LEF1%0'  ' DAAM1%0')  ('LEF1%0'  ' SFRP1_g%0')  ('LEF1%0'  ' PPM1A%0')  ('LEF1%0'  ' CFL_f%0')  ('LEF1%0'  ' PAK1%0')  ('LEF1%0'  ' MAP3K11%0')  ('LEF1%0'  ' MAP3K4%0')  ('LEF1%0'  ' LIMK1%0')  ('LEF1%0'  ' ROCK1%0')  ('LEF1%0'  ' ITCH%0')  ('LEF1%0'  ' ARHGAP24%0')  ('LEF1%0'  ' TIAM1%0')  ('LEF1%0'  ' RND3%0')  ('LEF1%0'  ' MAPK8IP3%0')  ('LEF1%0'  ' MXD1%0')  ('LEF1%0'  ' PIP3%0')  ('SFRP1%0'  ' SRC%0')  ('SFRP1%0'  ' CSK%0')  ('SFRP1%0'  ' CHUK%0')  ('SFRP1%0'  ' RAC_f%0')  ('SFRP1%0'  ' DUSP1%0')  ('SFRP1%0'  ' TGFBR2%0')  ('SFRP1%0'  ' ILR_f%0')  ('SFRP1%0'  ' SYK%0')  ('SFRP1%0'  ' IRAK1%0')  ('SFRP1%0'  ' SHC1%0')  ('SFRP1%0'  ' JAK_f%0')  ('SFRP1%0'  ' CBPp300_c%0')  ('SFRP1%0'  ' SKP2%0')  ('SFRP1%0'  ' TP53%0')  ('SFRP1%0'  ' SMAD7%0')  ('SFRP1%0'  ' SMAD6%0')  ('SFRP1%0'  ' DKK_f%0')  ('SFRP1%0'  ' FOXO_f%0')  ('SFRP1%0'  ' TCF7_f%0')  ('SFRP1%0'  ' DKK_g%0')  ('SFRP1%0'  ' MYC%0')  ('SFRP1%0'  ' CCND1%0')  ('SFRP1%0'  ' EGR1%0')  ('SFRP1%0'  ' MMP_f%0')  ('SFRP1%0'  ' PTEN_g%0')  ('SFRP1%0'  ' RTPK_f%0')  ('SFRP1%0'  ' CTNNB1%0')  ('SFRP1%0'  'LEF1%0')  ('SFRP1%0'  'FZD_f%0')  ('SFRP1%0'  ' CASP8%0')  ('SFRP1%0'  ' REL_f%0')  ('SFRP1%0'  ' NFKB_f%0')  ('SFRP1%0'  ' DVL_f%0')  ('SFRP1%0'  ' LRP_f%0')  ('SFRP1%0'  ' BTRC%0')  ('SFRP1%0'  ' CK1_f%0')  ('SFRP1%0'  ' AXIN1%0')  ('SFRP1%0'  ' mTORC2_c%0')  ('SFRP1%0'  ' PDPK1%0')  ('SFRP1%0'  ' MEK_f%0')  ('SFRP1%0'  ' CYCS%0')  ('SFRP1%0'  ' CASP9%0')  ('SFRP1%0'  ' GSK3_f%0')  ('SFRP1%0'  ' IRS1%0')  ('SFRP1%0'  ' MDM2%0')  ('SFRP1%0'  ' AKT_f%0')  ('SFRP1%0'  ' BCL2%0')  ('SFRP1%0'  ' RAF_f%0')  ('SFRP1%0'  ' mTORC1_c%0')  ('SFRP1%0'  ' RHEB%0')  ('SFRP1%0'  ' RTPK_g%0')  ('SFRP1%0'  ' PTEN%0')  ('SFRP1%0'  ' CASP3%0')  ('SFRP1%0'  ' PIK3CA%0')  ('SFRP1%0'  ' CREBBP%0')  ('SFRP1%0'  ' PTPN11%0')  ('SFRP1%0'  ' KRAS%0')  ('SFRP1%0'  ' MAP2K4%0')  ('SFRP1%0'  ' MAP2K7%0')  ('SFRP1%0'  ' MAPK14%0')  ('SFRP1%0'  ' JNK_f%0')  ('SFRP1%0'  ' MAP2K3%0')  ('SFRP1%0'  ' ERK_f%0')  ('SFRP1%0'  ' LIF%0')  ('SFRP1%0'  ' PPP1CA%0')  ('SFRP1%0'  ' GAB_f%0')  ('SFRP1%0'  ' SOS1%0')  ('SFRP1%0'  ' PRKCA%0')  ('SFRP1%0'  ' VAV1%0')  ('SFRP1%0'  ' PLCG1%0')  ('SFRP1%0'  ' PRKCD%0')  ('SFRP1%0'  ' RSK_f%0')  ('SFRP1%0'  ' S6K_f%0')  ('SFRP1%0'  ' PLK1%0')  ('SFRP1%0'  ' ILK%0')  ('SFRP1%0'  ' SOCS1%0')  ('SFRP1%0'  ' DUSP6%0')  ('SFRP1%0'  ' STAT3%0')  ('SFRP1%0'  ' LIMK2%0')  ('SFRP1%0'  ' EP300%0')  ('SFRP1%0'  ' STAT1%0')  ('SFRP1%0'  ' IKBKB%0')  ('SFRP1%0'  ' SRF%0')  ('SFRP1%0'  ' PIAS1%0')  ('SFRP1%0'  ' TRAF6%0')  ('SFRP1%0'  ' SOCS1_g%0')  ('SFRP1%0'  ' ISGF3_c%0')  ('SFRP1%0'  ' STAT2%0')  ('SFRP1%0'  ' CFLAR%0')  ('SFRP1%0'  ' SMAD2%0')  ('SFRP1%0'  ' MDM2_g%0')  ('SFRP1%0'  ' BAX%0')  ('SFRP1%0'  ' PRKACA%0')  ('SFRP1%0'  ' TGFB1%0')  ('SFRP1%0'  ' MAP3K8%0')  ('SFRP1%0'  ' TSC_f%0')  ('SFRP1%0'  ' SMAD4%0')  ('SFRP1%0'  ' BAD%0')  ('SFRP1%0'  ' MAP3K5%0')  ('SFRP1%0'  ' AKT1S1%0')  ('SFRP1%0'  ' SKI%0')  ('SFRP1%0'  ' SMAD3%0')  ('SFRP1%0'  ' MAPKAPK2%0')  ('SFRP1%0'  ' DUSP1_g%0')  ('SFRP1%0'  ' MSK_f%0')  ('SFRP1%0'  ' GRAP2%0')  ('SFRP1%0'  ' TAB_f%0')  ('SFRP1%0'  ' ATF2%0')  ('SFRP1%0'  ' SMAD5%0')  ('SFRP1%0'  ' SMAD1%0')  ('SFRP1%0'  ' FOS%0')  ('SFRP1%0'  ' JUN%0')  ('SFRP1%0'  ' MAP3K7%0')  ('SFRP1%0'  ' NLK%0')  ('SFRP1%0'  ' SMAD7_g%0')  ('SFRP1%0'  ' SMAD6_g%0')  ('SFRP1%0'  ' AP1_c%0')  ('SFRP1%0'  ' ACVR1%0')  ('SFRP1%0'  ' PTPN6%0')  ('SFRP1%0'  ' CDC42%0')  ('SFRP1%0'  ' GRB2%0')  ('SFRP1%0'  ' TGFBR1%0')  ('SFRP1%0'  ' SMURF1%0')  ('SFRP1%0'  ' SMURF2%0')  ('SFRP1%0'  ' RHOA%0')  ('SFRP1%0'  ' BMPR2%0')  ('SFRP1%0'  ' PARD6A%0')  ('SFRP1%0'  ' DAAM1%0')  ('SFRP1%0'  ' SFRP1_g%0')  ('SFRP1%0'  ' PPM1A%0')  ('SFRP1%0'  ' CFL_f%0')  ('SFRP1%0'  ' PAK1%0')  ('SFRP1%0'  ' MAP3K11%0')  ('SFRP1%0'  ' MAP3K4%0')  ('SFRP1%0'  ' LIMK1%0')  ('SFRP1%0'  ' ROCK1%0')  ('SFRP1%0'  ' ITCH%0')  ('SFRP1%0'  ' ARHGAP24%0')  ('SFRP1%0'  ' TIAM1%0')  ('SFRP1%0'  ' RND3%0')  ('SFRP1%0'  ' MAPK8IP3%0')  ('SFRP1%0'  ' MXD1%0')  ('SFRP1%0'  ' PIP3%0')  ('FZD_f%0'  ' SRC%0')  ('FZD_f%0'  ' CSK%0')  ('FZD_f%0'  ' CHUK%0')  ('FZD_f%0'  ' RAC_f%0')  ('FZD_f%0'  ' DUSP1%0')  ('FZD_f%0'  ' TGFBR2%0')  ('FZD_f%0'  ' ILR_f%0')  ('FZD_f%0'  ' SYK%0')  ('FZD_f%0'  ' IRAK1%0')  ('FZD_f%0'  ' SHC1%0')  ('FZD_f%0'  ' JAK_f%0')  ('FZD_f%0'  ' CBPp300_c%0')  ('FZD_f%0'  ' SKP2%0')  ('FZD_f%0'  ' TP53%0')  ('FZD_f%0'  ' SMAD7%0')  ('FZD_f%0'  ' SMAD6%0')  ('FZD_f%0'  ' DKK_f%0')  ('FZD_f%0'  ' FOXO_f%0')  ('FZD_f%0'  ' TCF7_f%0')  ('FZD_f%0'  ' DKK_g%0')  ('FZD_f%0'  ' MYC%0')  ('FZD_f%0'  ' CCND1%0')  ('FZD_f%0'  ' EGR1%0')  ('FZD_f%0'  ' MMP_f%0')  ('FZD_f%0'  ' PTEN_g%0')  ('FZD_f%0'  ' RTPK_f%0')  ('FZD_f%0'  ' CTNNB1%0')  ('FZD_f%0'  'LEF1%0')  ('FZD_f%0'  'SFRP1%0')  ('FZD_f%0'  ' CASP8%0')  ('FZD_f%0'  ' REL_f%0')  ('FZD_f%0'  ' NFKB_f%0')  ('FZD_f%0'  ' DVL_f%0')  ('FZD_f%0'  ' LRP_f%0')  ('FZD_f%0'  ' BTRC%0')  ('FZD_f%0'  ' CK1_f%0')  ('FZD_f%0'  ' AXIN1%0')  ('FZD_f%0'  ' mTORC2_c%0')  ('FZD_f%0'  ' PDPK1%0')  ('FZD_f%0'  ' MEK_f%0')  ('FZD_f%0'  ' CYCS%0')  ('FZD_f%0'  ' CASP9%0')  ('FZD_f%0'  ' GSK3_f%0')  ('FZD_f%0'  ' IRS1%0')  ('FZD_f%0'  ' MDM2%0')  ('FZD_f%0'  ' AKT_f%0')  ('FZD_f%0'  ' BCL2%0')  ('FZD_f%0'  ' RAF_f%0')  ('FZD_f%0'  ' mTORC1_c%0')  ('FZD_f%0'  ' RHEB%0')  ('FZD_f%0'  ' RTPK_g%0')  ('FZD_f%0'  ' PTEN%0')  ('FZD_f%0'  ' CASP3%0')  ('FZD_f%0'  ' PIK3CA%0')  ('FZD_f%0'  ' CREBBP%0')  ('FZD_f%0'  ' PTPN11%0')  ('FZD_f%0'  ' KRAS%0')  ('FZD_f%0'  ' MAP2K4%0')  ('FZD_f%0'  ' MAP2K7%0')  ('FZD_f%0'  ' MAPK14%0')  ('FZD_f%0'  ' JNK_f%0')  ('FZD_f%0'  ' MAP2K3%0')  ('FZD_f%0'  ' ERK_f%0')  ('FZD_f%0'  ' LIF%0')  ('FZD_f%0'  ' PPP1CA%0')  ('FZD_f%0'  ' GAB_f%0')  ('FZD_f%0'  ' SOS1%0')  ('FZD_f%0'  ' PRKCA%0')  ('FZD_f%0'  ' VAV1%0')  ('FZD_f%0'  ' PLCG1%0')  ('FZD_f%0'  ' PRKCD%0')  ('FZD_f%0'  ' RSK_f%0')  ('FZD_f%0'  ' S6K_f%0')  ('FZD_f%0'  ' PLK1%0')  ('FZD_f%0'  ' ILK%0')  ('FZD_f%0'  ' SOCS1%0')  ('FZD_f%0'  ' DUSP6%0')  ('FZD_f%0'  ' STAT3%0')  ('FZD_f%0'  ' LIMK2%0')  ('FZD_f%0'  ' EP300%0')  ('FZD_f%0'  ' STAT1%0')  ('FZD_f%0'  ' IKBKB%0')  ('FZD_f%0'  ' SRF%0')  ('FZD_f%0'  ' PIAS1%0')  ('FZD_f%0'  ' TRAF6%0')  ('FZD_f%0'  ' SOCS1_g%0')  ('FZD_f%0'  ' ISGF3_c%0')  ('FZD_f%0'  ' STAT2%0')  ('FZD_f%0'  ' CFLAR%0')  ('FZD_f%0'  ' SMAD2%0')  ('FZD_f%0'  ' MDM2_g%0')  ('FZD_f%0'  ' BAX%0')  ('FZD_f%0'  ' PRKACA%0')  ('FZD_f%0'  ' TGFB1%0')  ('FZD_f%0'  ' MAP3K8%0')  ('FZD_f%0'  ' TSC_f%0')  ('FZD_f%0'  ' SMAD4%0')  ('FZD_f%0'  ' BAD%0')  ('FZD_f%0'  ' MAP3K5%0')  ('FZD_f%0'  ' AKT1S1%0')  ('FZD_f%0'  ' SKI%0')  ('FZD_f%0'  ' SMAD3%0')  ('FZD_f%0'  ' MAPKAPK2%0')  ('FZD_f%0'  ' DUSP1_g%0')  ('FZD_f%0'  ' MSK_f%0')  ('FZD_f%0'  ' GRAP2%0')  ('FZD_f%0'  ' TAB_f%0')  ('FZD_f%0'  ' ATF2%0')  ('FZD_f%0'  ' SMAD5%0')  ('FZD_f%0'  ' SMAD1%0')  ('FZD_f%0'  ' FOS%0')  ('FZD_f%0'  ' JUN%0')  ('FZD_f%0'  ' MAP3K7%0')  ('FZD_f%0'  ' NLK%0')  ('FZD_f%0'  ' SMAD7_g%0')  ('FZD_f%0'  ' SMAD6_g%0')  ('FZD_f%0'  ' AP1_c%0')  ('FZD_f%0'  ' ACVR1%0')  ('FZD_f%0'  ' PTPN6%0')  ('FZD_f%0'  ' CDC42%0')  ('FZD_f%0'  ' GRB2%0')  ('FZD_f%0'  ' TGFBR1%0')  ('FZD_f%0'  ' SMURF1%0')  ('FZD_f%0'  ' SMURF2%0')  ('FZD_f%0'  ' RHOA%0')  ('FZD_f%0'  ' BMPR2%0')  ('FZD_f%0'  ' PARD6A%0')  ('FZD_f%0'  ' DAAM1%0')  ('FZD_f%0'  ' SFRP1_g%0')  ('FZD_f%0'  ' PPM1A%0')  ('FZD_f%0'  ' CFL_f%0')  ('FZD_f%0'  ' PAK1%0')  ('FZD_f%0'  ' MAP3K11%0')  ('FZD_f%0'  ' MAP3K4%0')  ('FZD_f%0'  ' LIMK1%0')  ('FZD_f%0'  ' ROCK1%0')  ('FZD_f%0'  ' ITCH%0')  ('FZD_f%0'  ' ARHGAP24%0')  ('FZD_f%0'  ' TIAM1%0')  ('FZD_f%0'  ' RND3%0')  ('FZD_f%0'  ' MAPK8IP3%0')  ('FZD_f%0'  ' MXD1%0')  ('FZD_f%0'  ' PIP3%0')  (' CASP8%0'  ' SRC%0')  (' CASP8%0'  ' CSK%0')  (' CASP8%0'  ' CHUK%0')  (' CASP8%0'  ' RAC_f%0')  (' CASP8%0'  ' DUSP1%0')  (' CASP8%0'  ' TGFBR2%0')  (' CASP8%0'  ' ILR_f%0')  (' CASP8%0'  ' SYK%0')  (' CASP8%0'  ' IRAK1%0')  (' CASP8%0'  ' SHC1%0')  (' CASP8%0'  ' JAK_f%0')  (' CASP8%0'  ' CBPp300_c%0')  (' CASP8%0'  ' SKP2%0')  (' CASP8%0'  ' TP53%0')  (' CASP8%0'  ' SMAD7%0')  (' CASP8%0'  ' SMAD6%0')  (' CASP8%0'  ' DKK_f%0')  (' CASP8%0'  ' FOXO_f%0')  (' CASP8%0'  ' TCF7_f%0')  (' CASP8%0'  ' DKK_g%0')  (' CASP8%0'  ' MYC%0')  (' CASP8%0'  ' CCND1%0')  (' CASP8%0'  ' EGR1%0')  (' CASP8%0'  ' MMP_f%0')  (' CASP8%0'  ' PTEN_g%0')  (' CASP8%0'  ' RTPK_f%0')  (' CASP8%0'  ' CTNNB1%0')  (' CASP8%0'  'LEF1%0')  (' CASP8%0'  'SFRP1%0')  (' CASP8%0'  'FZD_f%0')  (' CASP8%0'  ' REL_f%0')  (' CASP8%0'  ' NFKB_f%0')  (' CASP8%0'  ' DVL_f%0')  (' CASP8%0'  ' LRP_f%0')  (' CASP8%0'  ' BTRC%0')  (' CASP8%0'  ' CK1_f%0')  (' CASP8%0'  ' AXIN1%0')  (' CASP8%0'  ' mTORC2_c%0')  (' CASP8%0'  ' PDPK1%0')  (' CASP8%0'  ' MEK_f%0')  (' CASP8%0'  ' CYCS%0')  (' CASP8%0'  ' CASP9%0')  (' CASP8%0'  ' GSK3_f%0')  (' CASP8%0'  ' IRS1%0')  (' CASP8%0'  ' MDM2%0')  (' CASP8%0'  ' AKT_f%0')  (' CASP8%0'  ' BCL2%0')  (' CASP8%0'  ' RAF_f%0')  (' CASP8%0'  ' mTORC1_c%0')  (' CASP8%0'  ' RHEB%0')  (' CASP8%0'  ' RTPK_g%0')  (' CASP8%0'  ' PTEN%0')  (' CASP8%0'  ' CASP3%0')  (' CASP8%0'  ' PIK3CA%0')  (' CASP8%0'  ' CREBBP%0')  (' CASP8%0'  ' PTPN11%0')  (' CASP8%0'  ' KRAS%0')  (' CASP8%0'  ' MAP2K4%0')  (' CASP8%0'  ' MAP2K7%0')  (' CASP8%0'  ' MAPK14%0')  (' CASP8%0'  ' JNK_f%0')  (' CASP8%0'  ' MAP2K3%0')  (' CASP8%0'  ' ERK_f%0')  (' CASP8%0'  ' LIF%0')  (' CASP8%0'  ' PPP1CA%0')  (' CASP8%0'  ' GAB_f%0')  (' CASP8%0'  ' SOS1%0')  (' CASP8%0'  ' PRKCA%0')  (' CASP8%0'  ' VAV1%0')  (' CASP8%0'  ' PLCG1%0')  (' CASP8%0'  ' PRKCD%0')  (' CASP8%0'  ' RSK_f%0')  (' CASP8%0'  ' S6K_f%0')  (' CASP8%0'  ' PLK1%0')  (' CASP8%0'  ' ILK%0')  (' CASP8%0'  ' SOCS1%0')  (' CASP8%0'  ' DUSP6%0')  (' CASP8%0'  ' STAT3%0')  (' CASP8%0'  ' LIMK2%0')  (' CASP8%0'  ' EP300%0')  (' CASP8%0'  ' STAT1%0')  (' CASP8%0'  ' IKBKB%0')  (' CASP8%0'  ' SRF%0')  (' CASP8%0'  ' PIAS1%0')  (' CASP8%0'  ' TRAF6%0')  (' CASP8%0'  ' SOCS1_g%0')  (' CASP8%0'  ' ISGF3_c%0')  (' CASP8%0'  ' STAT2%0')  (' CASP8%0'  ' CFLAR%0')  (' CASP8%0'  ' SMAD2%0')  (' CASP8%0'  ' MDM2_g%0')  (' CASP8%0'  ' BAX%0')  (' CASP8%0'  ' PRKACA%0')  (' CASP8%0'  ' TGFB1%0')  (' CASP8%0'  ' MAP3K8%0')  (' CASP8%0'  ' TSC_f%0')  (' CASP8%0'  ' SMAD4%0')  (' CASP8%0'  ' BAD%0')  (' CASP8%0'  ' MAP3K5%0')  (' CASP8%0'  ' AKT1S1%0')  (' CASP8%0'  ' SKI%0')  (' CASP8%0'  ' SMAD3%0')  (' CASP8%0'  ' MAPKAPK2%0')  (' CASP8%0'  ' DUSP1_g%0')  (' CASP8%0'  ' MSK_f%0')  (' CASP8%0'  ' GRAP2%0')  (' CASP8%0'  ' TAB_f%0')  (' CASP8%0'  ' ATF2%0')  (' CASP8%0'  ' SMAD5%0')  (' CASP8%0'  ' SMAD1%0')  (' CASP8%0'  ' FOS%0')  (' CASP8%0'  ' JUN%0')  (' CASP8%0'  ' MAP3K7%0')  (' CASP8%0'  ' NLK%0')  (' CASP8%0'  ' SMAD7_g%0')  (' CASP8%0'  ' SMAD6_g%0')  (' CASP8%0'  ' AP1_c%0')  (' CASP8%0'  ' ACVR1%0')  (' CASP8%0'  ' PTPN6%0')  (' CASP8%0'  ' CDC42%0')  (' CASP8%0'  ' GRB2%0')  (' CASP8%0'  ' TGFBR1%0')  (' CASP8%0'  ' SMURF1%0')  (' CASP8%0'  ' SMURF2%0')  (' CASP8%0'  ' RHOA%0')  (' CASP8%0'  ' BMPR2%0')  (' CASP8%0'  ' PARD6A%0')  (' CASP8%0'  ' DAAM1%0')  (' CASP8%0'  ' SFRP1_g%0')  (' CASP8%0'  ' PPM1A%0')  (' CASP8%0'  ' CFL_f%0')  (' CASP8%0'  ' PAK1%0')  (' CASP8%0'  ' MAP3K11%0')  (' CASP8%0'  ' MAP3K4%0')  (' CASP8%0'  ' LIMK1%0')  (' CASP8%0'  ' ROCK1%0')  (' CASP8%0'  ' ITCH%0')  (' CASP8%0'  ' ARHGAP24%0')  (' CASP8%0'  ' TIAM1%0')  (' CASP8%0'  ' RND3%0')  (' CASP8%0'  ' MAPK8IP3%0')  (' CASP8%0'  ' MXD1%0')  (' CASP8%0'  ' PIP3%0')  (' REL_f%0'  ' SRC%0')  (' REL_f%0'  ' CSK%0')  (' REL_f%0'  ' CHUK%0')  (' REL_f%0'  ' RAC_f%0')  (' REL_f%0'  ' DUSP1%0')  (' REL_f%0'  ' TGFBR2%0')  (' REL_f%0'  ' ILR_f%0')  (' REL_f%0'  ' SYK%0')  (' REL_f%0'  ' IRAK1%0')  (' REL_f%0'  ' SHC1%0')  (' REL_f%0'  ' JAK_f%0')  (' REL_f%0'  ' CBPp300_c%0')  (' REL_f%0'  ' SKP2%0')  (' REL_f%0'  ' TP53%0')  (' REL_f%0'  ' SMAD7%0')  (' REL_f%0'  ' SMAD6%0')  (' REL_f%0'  ' DKK_f%0')  (' REL_f%0'  ' FOXO_f%0')  (' REL_f%0'  ' TCF7_f%0')  (' REL_f%0'  ' DKK_g%0')  (' REL_f%0'  ' MYC%0')  (' REL_f%0'  ' CCND1%0')  (' REL_f%0'  ' EGR1%0')  (' REL_f%0'  ' MMP_f%0')  (' REL_f%0'  ' PTEN_g%0')  (' REL_f%0'  ' RTPK_f%0')  (' REL_f%0'  ' CTNNB1%0')  (' REL_f%0'  'LEF1%0')  (' REL_f%0'  'SFRP1%0')  (' REL_f%0'  'FZD_f%0')  (' REL_f%0'  ' CASP8%0')  (' REL_f%0'  ' NFKB_f%0')  (' REL_f%0'  ' DVL_f%0')  (' REL_f%0'  ' LRP_f%0')  (' REL_f%0'  ' BTRC%0')  (' REL_f%0'  ' CK1_f%0')  (' REL_f%0'  ' AXIN1%0')  (' REL_f%0'  ' mTORC2_c%0')  (' REL_f%0'  ' PDPK1%0')  (' REL_f%0'  ' MEK_f%0')  (' REL_f%0'  ' CYCS%0')  (' REL_f%0'  ' CASP9%0')  (' REL_f%0'  ' GSK3_f%0')  (' REL_f%0'  ' IRS1%0')  (' REL_f%0'  ' MDM2%0')  (' REL_f%0'  ' AKT_f%0')  (' REL_f%0'  ' BCL2%0')  (' REL_f%0'  ' RAF_f%0')  (' REL_f%0'  ' mTORC1_c%0')  (' REL_f%0'  ' RHEB%0')  (' REL_f%0'  ' RTPK_g%0')  (' REL_f%0'  ' PTEN%0')  (' REL_f%0'  ' CASP3%0')  (' REL_f%0'  ' PIK3CA%0')  (' REL_f%0'  ' CREBBP%0')  (' REL_f%0'  ' PTPN11%0')  (' REL_f%0'  ' KRAS%0')  (' REL_f%0'  ' MAP2K4%0')  (' REL_f%0'  ' MAP2K7%0')  (' REL_f%0'  ' MAPK14%0')  (' REL_f%0'  ' JNK_f%0')  (' REL_f%0'  ' MAP2K3%0')  (' REL_f%0'  ' ERK_f%0')  (' REL_f%0'  ' LIF%0')  (' REL_f%0'  ' PPP1CA%0')  (' REL_f%0'  ' GAB_f%0')  (' REL_f%0'  ' SOS1%0')  (' REL_f%0'  ' PRKCA%0')  (' REL_f%0'  ' VAV1%0')  (' REL_f%0'  ' PLCG1%0')  (' REL_f%0'  ' PRKCD%0')  (' REL_f%0'  ' RSK_f%0')  (' REL_f%0'  ' S6K_f%0')  (' REL_f%0'  ' PLK1%0')  (' REL_f%0'  ' ILK%0')  (' REL_f%0'  ' SOCS1%0')  (' REL_f%0'  ' DUSP6%0')  (' REL_f%0'  ' STAT3%0')  (' REL_f%0'  ' LIMK2%0')  (' REL_f%0'  ' EP300%0')  (' REL_f%0'  ' STAT1%0')  (' REL_f%0'  ' IKBKB%0')  (' REL_f%0'  ' SRF%0')  (' REL_f%0'  ' PIAS1%0')  (' REL_f%0'  ' TRAF6%0')  (' REL_f%0'  ' SOCS1_g%0')  (' REL_f%0'  ' ISGF3_c%0')  (' REL_f%0'  ' STAT2%0')  (' REL_f%0'  ' CFLAR%0')  (' REL_f%0'  ' SMAD2%0')  (' REL_f%0'  ' MDM2_g%0')  (' REL_f%0'  ' BAX%0')  (' REL_f%0'  ' PRKACA%0')  (' REL_f%0'  ' TGFB1%0')  (' REL_f%0'  ' MAP3K8%0')  (' REL_f%0'  ' TSC_f%0')  (' REL_f%0'  ' SMAD4%0')  (' REL_f%0'  ' BAD%0')  (' REL_f%0'  ' MAP3K5%0')  (' REL_f%0'  ' AKT1S1%0')  (' REL_f%0'  ' SKI%0')  (' REL_f%0'  ' SMAD3%0')  (' REL_f%0'  ' MAPKAPK2%0')  (' REL_f%0'  ' DUSP1_g%0')  (' REL_f%0'  ' MSK_f%0')  (' REL_f%0'  ' GRAP2%0')  (' REL_f%0'  ' TAB_f%0')  (' REL_f%0'  ' ATF2%0')  (' REL_f%0'  ' SMAD5%0')  (' REL_f%0'  ' SMAD1%0')  (' REL_f%0'  ' FOS%0')  (' REL_f%0'  ' JUN%0')  (' REL_f%0'  ' MAP3K7%0')  (' REL_f%0'  ' NLK%0')  (' REL_f%0'  ' SMAD7_g%0')  (' REL_f%0'  ' SMAD6_g%0')  (' REL_f%0'  ' AP1_c%0')  (' REL_f%0'  ' ACVR1%0')  (' REL_f%0'  ' PTPN6%0')  (' REL_f%0'  ' CDC42%0')  (' REL_f%0'  ' GRB2%0')  (' REL_f%0'  ' TGFBR1%0')  (' REL_f%0'  ' SMURF1%0')  (' REL_f%0'  ' SMURF2%0')  (' REL_f%0'  ' RHOA%0')  (' REL_f%0'  ' BMPR2%0')  (' REL_f%0'  ' PARD6A%0')  (' REL_f%0'  ' DAAM1%0')  (' REL_f%0'  ' SFRP1_g%0')  (' REL_f%0'  ' PPM1A%0')  (' REL_f%0'  ' CFL_f%0')  (' REL_f%0'  ' PAK1%0')  (' REL_f%0'  ' MAP3K11%0')  (' REL_f%0'  ' MAP3K4%0')  (' REL_f%0'  ' LIMK1%0')  (' REL_f%0'  ' ROCK1%0')  (' REL_f%0'  ' ITCH%0')  (' REL_f%0'  ' ARHGAP24%0')  (' REL_f%0'  ' TIAM1%0')  (' REL_f%0'  ' RND3%0')  (' REL_f%0'  ' MAPK8IP3%0')  (' REL_f%0'  ' MXD1%0')  (' REL_f%0'  ' PIP3%0')  (' NFKB_f%0'  ' SRC%0')  (' NFKB_f%0'  ' CSK%0')  (' NFKB_f%0'  ' CHUK%0')  (' NFKB_f%0'  ' RAC_f%0')  (' NFKB_f%0'  ' DUSP1%0')  (' NFKB_f%0'  ' TGFBR2%0')  (' NFKB_f%0'  ' ILR_f%0')  (' NFKB_f%0'  ' SYK%0')  (' NFKB_f%0'  ' IRAK1%0')  (' NFKB_f%0'  ' SHC1%0')  (' NFKB_f%0'  ' JAK_f%0')  (' NFKB_f%0'  ' CBPp300_c%0')  (' NFKB_f%0'  ' SKP2%0')  (' NFKB_f%0'  ' TP53%0')  (' NFKB_f%0'  ' SMAD7%0')  (' NFKB_f%0'  ' SMAD6%0')  (' NFKB_f%0'  ' DKK_f%0')  (' NFKB_f%0'  ' FOXO_f%0')  (' NFKB_f%0'  ' TCF7_f%0')  (' NFKB_f%0'  ' DKK_g%0')  (' NFKB_f%0'  ' MYC%0')  (' NFKB_f%0'  ' CCND1%0')  (' NFKB_f%0'  ' EGR1%0')  (' NFKB_f%0'  ' MMP_f%0')  (' NFKB_f%0'  ' PTEN_g%0')  (' NFKB_f%0'  ' RTPK_f%0')  (' NFKB_f%0'  ' CTNNB1%0')  (' NFKB_f%0'  'LEF1%0')  (' NFKB_f%0'  'SFRP1%0')  (' NFKB_f%0'  'FZD_f%0')  (' NFKB_f%0'  ' CASP8%0')  (' NFKB_f%0'  ' REL_f%0')  (' NFKB_f%0'  ' DVL_f%0')  (' NFKB_f%0'  ' LRP_f%0')  (' NFKB_f%0'  ' BTRC%0')  (' NFKB_f%0'  ' CK1_f%0')  (' NFKB_f%0'  ' AXIN1%0')  (' NFKB_f%0'  ' mTORC2_c%0')  (' NFKB_f%0'  ' PDPK1%0')  (' NFKB_f%0'  ' MEK_f%0')  (' NFKB_f%0'  ' CYCS%0')  (' NFKB_f%0'  ' CASP9%0')  (' NFKB_f%0'  ' GSK3_f%0')  (' NFKB_f%0'  ' IRS1%0')  (' NFKB_f%0'  ' MDM2%0')  (' NFKB_f%0'  ' AKT_f%0')  (' NFKB_f%0'  ' BCL2%0')  (' NFKB_f%0'  ' RAF_f%0')  (' NFKB_f%0'  ' mTORC1_c%0')  (' NFKB_f%0'  ' RHEB%0')  (' NFKB_f%0'  ' RTPK_g%0')  (' NFKB_f%0'  ' PTEN%0')  (' NFKB_f%0'  ' CASP3%0')  (' NFKB_f%0'  ' PIK3CA%0')  (' NFKB_f%0'  ' CREBBP%0')  (' NFKB_f%0'  ' PTPN11%0')  (' NFKB_f%0'  ' KRAS%0')  (' NFKB_f%0'  ' MAP2K4%0')  (' NFKB_f%0'  ' MAP2K7%0')  (' NFKB_f%0'  ' MAPK14%0')  (' NFKB_f%0'  ' JNK_f%0')  (' NFKB_f%0'  ' MAP2K3%0')  (' NFKB_f%0'  ' ERK_f%0')  (' NFKB_f%0'  ' LIF%0')  (' NFKB_f%0'  ' PPP1CA%0')  (' NFKB_f%0'  ' GAB_f%0')  (' NFKB_f%0'  ' SOS1%0')  (' NFKB_f%0'  ' PRKCA%0')  (' NFKB_f%0'  ' VAV1%0')  (' NFKB_f%0'  ' PLCG1%0')  (' NFKB_f%0'  ' PRKCD%0')  (' NFKB_f%0'  ' RSK_f%0')  (' NFKB_f%0'  ' S6K_f%0')  (' NFKB_f%0'  ' PLK1%0')  (' NFKB_f%0'  ' ILK%0')  (' NFKB_f%0'  ' SOCS1%0')  (' NFKB_f%0'  ' DUSP6%0')  (' NFKB_f%0'  ' STAT3%0')  (' NFKB_f%0'  ' LIMK2%0')  (' NFKB_f%0'  ' EP300%0')  (' NFKB_f%0'  ' STAT1%0')  (' NFKB_f%0'  ' IKBKB%0')  (' NFKB_f%0'  ' SRF%0')  (' NFKB_f%0'  ' PIAS1%0')  (' NFKB_f%0'  ' TRAF6%0')  (' NFKB_f%0'  ' SOCS1_g%0')  (' NFKB_f%0'  ' ISGF3_c%0')  (' NFKB_f%0'  ' STAT2%0')  (' NFKB_f%0'  ' CFLAR%0')  (' NFKB_f%0'  ' SMAD2%0')  (' NFKB_f%0'  ' MDM2_g%0')  (' NFKB_f%0'  ' BAX%0')  (' NFKB_f%0'  ' PRKACA%0')  (' NFKB_f%0'  ' TGFB1%0')  (' NFKB_f%0'  ' MAP3K8%0')  (' NFKB_f%0'  ' TSC_f%0')  (' NFKB_f%0'  ' SMAD4%0')  (' NFKB_f%0'  ' BAD%0')  (' NFKB_f%0'  ' MAP3K5%0')  (' NFKB_f%0'  ' AKT1S1%0')  (' NFKB_f%0'  ' SKI%0')  (' NFKB_f%0'  ' SMAD3%0')  (' NFKB_f%0'  ' MAPKAPK2%0')  (' NFKB_f%0'  ' DUSP1_g%0')  (' NFKB_f%0'  ' MSK_f%0')  (' NFKB_f%0'  ' GRAP2%0')  (' NFKB_f%0'  ' TAB_f%0')  (' NFKB_f%0'  ' ATF2%0')  (' NFKB_f%0'  ' SMAD5%0')  (' NFKB_f%0'  ' SMAD1%0')  (' NFKB_f%0'  ' FOS%0')  (' NFKB_f%0'  ' JUN%0')  (' NFKB_f%0'  ' MAP3K7%0')  (' NFKB_f%0'  ' NLK%0')  (' NFKB_f%0'  ' SMAD7_g%0')  (' NFKB_f%0'  ' SMAD6_g%0')  (' NFKB_f%0'  ' AP1_c%0')  (' NFKB_f%0'  ' ACVR1%0')  (' NFKB_f%0'  ' PTPN6%0')  (' NFKB_f%0'  ' CDC42%0')  (' NFKB_f%0'  ' GRB2%0')  (' NFKB_f%0'  ' TGFBR1%0')  (' NFKB_f%0'  ' SMURF1%0')  (' NFKB_f%0'  ' SMURF2%0')  (' NFKB_f%0'  ' RHOA%0')  (' NFKB_f%0'  ' BMPR2%0')  (' NFKB_f%0'  ' PARD6A%0')  (' NFKB_f%0'  ' DAAM1%0')  (' NFKB_f%0'  ' SFRP1_g%0')  (' NFKB_f%0'  ' PPM1A%0')  (' NFKB_f%0'  ' CFL_f%0')  (' NFKB_f%0'  ' PAK1%0')  (' NFKB_f%0'  ' MAP3K11%0')  (' NFKB_f%0'  ' MAP3K4%0')  (' NFKB_f%0'  ' LIMK1%0')  (' NFKB_f%0'  ' ROCK1%0')  (' NFKB_f%0'  ' ITCH%0')  (' NFKB_f%0'  ' ARHGAP24%0')  (' NFKB_f%0'  ' TIAM1%0')  (' NFKB_f%0'  ' RND3%0')  (' NFKB_f%0'  ' MAPK8IP3%0')  (' NFKB_f%0'  ' MXD1%0')  (' NFKB_f%0'  ' PIP3%0')  (' DVL_f%0'  ' SRC%0')  (' DVL_f%0'  ' CSK%0')  (' DVL_f%0'  ' CHUK%0')  (' DVL_f%0'  ' RAC_f%0')  (' DVL_f%0'  ' DUSP1%0')  (' DVL_f%0'  ' TGFBR2%0')  (' DVL_f%0'  ' ILR_f%0')  (' DVL_f%0'  ' SYK%0')  (' DVL_f%0'  ' IRAK1%0')  (' DVL_f%0'  ' SHC1%0')  (' DVL_f%0'  ' JAK_f%0')  (' DVL_f%0'  ' CBPp300_c%0')  (' DVL_f%0'  ' SKP2%0')  (' DVL_f%0'  ' TP53%0')  (' DVL_f%0'  ' SMAD7%0')  (' DVL_f%0'  ' SMAD6%0')  (' DVL_f%0'  ' DKK_f%0')  (' DVL_f%0'  ' FOXO_f%0')  (' DVL_f%0'  ' TCF7_f%0')  (' DVL_f%0'  ' DKK_g%0')  (' DVL_f%0'  ' MYC%0')  (' DVL_f%0'  ' CCND1%0')  (' DVL_f%0'  ' EGR1%0')  (' DVL_f%0'  ' MMP_f%0')  (' DVL_f%0'  ' PTEN_g%0')  (' DVL_f%0'  ' RTPK_f%0')  (' DVL_f%0'  ' CTNNB1%0')  (' DVL_f%0'  'LEF1%0')  (' DVL_f%0'  'SFRP1%0')  (' DVL_f%0'  'FZD_f%0')  (' DVL_f%0'  ' CASP8%0')  (' DVL_f%0'  ' REL_f%0')  (' DVL_f%0'  ' NFKB_f%0')  (' DVL_f%0'  ' LRP_f%0')  (' DVL_f%0'  ' BTRC%0')  (' DVL_f%0'  ' CK1_f%0')  (' DVL_f%0'  ' AXIN1%0')  (' DVL_f%0'  ' mTORC2_c%0')  (' DVL_f%0'  ' PDPK1%0')  (' DVL_f%0'  ' MEK_f%0')  (' DVL_f%0'  ' CYCS%0')  (' DVL_f%0'  ' CASP9%0')  (' DVL_f%0'  ' GSK3_f%0')  (' DVL_f%0'  ' IRS1%0')  (' DVL_f%0'  ' MDM2%0')  (' DVL_f%0'  ' AKT_f%0')  (' DVL_f%0'  ' BCL2%0')  (' DVL_f%0'  ' RAF_f%0')  (' DVL_f%0'  ' mTORC1_c%0')  (' DVL_f%0'  ' RHEB%0')  (' DVL_f%0'  ' RTPK_g%0')  (' DVL_f%0'  ' PTEN%0')  (' DVL_f%0'  ' CASP3%0')  (' DVL_f%0'  ' PIK3CA%0')  (' DVL_f%0'  ' CREBBP%0')  (' DVL_f%0'  ' PTPN11%0')  (' DVL_f%0'  ' KRAS%0')  (' DVL_f%0'  ' MAP2K4%0')  (' DVL_f%0'  ' MAP2K7%0')  (' DVL_f%0'  ' MAPK14%0')  (' DVL_f%0'  ' JNK_f%0')  (' DVL_f%0'  ' MAP2K3%0')  (' DVL_f%0'  ' ERK_f%0')  (' DVL_f%0'  ' LIF%0')  (' DVL_f%0'  ' PPP1CA%0')  (' DVL_f%0'  ' GAB_f%0')  (' DVL_f%0'  ' SOS1%0')  (' DVL_f%0'  ' PRKCA%0')  (' DVL_f%0'  ' VAV1%0')  (' DVL_f%0'  ' PLCG1%0')  (' DVL_f%0'  ' PRKCD%0')  (' DVL_f%0'  ' RSK_f%0')  (' DVL_f%0'  ' S6K_f%0')  (' DVL_f%0'  ' PLK1%0')  (' DVL_f%0'  ' ILK%0')  (' DVL_f%0'  ' SOCS1%0')  (' DVL_f%0'  ' DUSP6%0')  (' DVL_f%0'  ' STAT3%0')  (' DVL_f%0'  ' LIMK2%0')  (' DVL_f%0'  ' EP300%0')  (' DVL_f%0'  ' STAT1%0')  (' DVL_f%0'  ' IKBKB%0')  (' DVL_f%0'  ' SRF%0')  (' DVL_f%0'  ' PIAS1%0')  (' DVL_f%0'  ' TRAF6%0')  (' DVL_f%0'  ' SOCS1_g%0')  (' DVL_f%0'  ' ISGF3_c%0')  (' DVL_f%0'  ' STAT2%0')  (' DVL_f%0'  ' CFLAR%0')  (' DVL_f%0'  ' SMAD2%0')  (' DVL_f%0'  ' MDM2_g%0')  (' DVL_f%0'  ' BAX%0')  (' DVL_f%0'  ' PRKACA%0')  (' DVL_f%0'  ' TGFB1%0')  (' DVL_f%0'  ' MAP3K8%0')  (' DVL_f%0'  ' TSC_f%0')  (' DVL_f%0'  ' SMAD4%0')  (' DVL_f%0'  ' BAD%0')  (' DVL_f%0'  ' MAP3K5%0')  (' DVL_f%0'  ' AKT1S1%0')  (' DVL_f%0'  ' SKI%0')  (' DVL_f%0'  ' SMAD3%0')  (' DVL_f%0'  ' MAPKAPK2%0')  (' DVL_f%0'  ' DUSP1_g%0')  (' DVL_f%0'  ' MSK_f%0')  (' DVL_f%0'  ' GRAP2%0')  (' DVL_f%0'  ' TAB_f%0')  (' DVL_f%0'  ' ATF2%0')  (' DVL_f%0'  ' SMAD5%0')  (' DVL_f%0'  ' SMAD1%0')  (' DVL_f%0'  ' FOS%0')  (' DVL_f%0'  ' JUN%0')  (' DVL_f%0'  ' MAP3K7%0')  (' DVL_f%0'  ' NLK%0')  (' DVL_f%0'  ' SMAD7_g%0')  (' DVL_f%0'  ' SMAD6_g%0')  (' DVL_f%0'  ' AP1_c%0')  (' DVL_f%0'  ' ACVR1%0')  (' DVL_f%0'  ' PTPN6%0')  (' DVL_f%0'  ' CDC42%0')  (' DVL_f%0'  ' GRB2%0')  (' DVL_f%0'  ' TGFBR1%0')  (' DVL_f%0'  ' SMURF1%0')  (' DVL_f%0'  ' SMURF2%0')  (' DVL_f%0'  ' RHOA%0')  (' DVL_f%0'  ' BMPR2%0')  (' DVL_f%0'  ' PARD6A%0')  (' DVL_f%0'  ' DAAM1%0')  (' DVL_f%0'  ' SFRP1_g%0')  (' DVL_f%0'  ' PPM1A%0')  (' DVL_f%0'  ' CFL_f%0')  (' DVL_f%0'  ' PAK1%0')  (' DVL_f%0'  ' MAP3K11%0')  (' DVL_f%0'  ' MAP3K4%0')  (' DVL_f%0'  ' LIMK1%0')  (' DVL_f%0'  ' ROCK1%0')  (' DVL_f%0'  ' ITCH%0')  (' DVL_f%0'  ' ARHGAP24%0')  (' DVL_f%0'  ' TIAM1%0')  (' DVL_f%0'  ' RND3%0')  (' DVL_f%0'  ' MAPK8IP3%0')  (' DVL_f%0'  ' MXD1%0')  (' DVL_f%0'  ' PIP3%0')  (' LRP_f%0'  ' SRC%0')  (' LRP_f%0'  ' CSK%0')  (' LRP_f%0'  ' CHUK%0')  (' LRP_f%0'  ' RAC_f%0')  (' LRP_f%0'  ' DUSP1%0')  (' LRP_f%0'  ' TGFBR2%0')  (' LRP_f%0'  ' ILR_f%0')  (' LRP_f%0'  ' SYK%0')  (' LRP_f%0'  ' IRAK1%0')  (' LRP_f%0'  ' SHC1%0')  (' LRP_f%0'  ' JAK_f%0')  (' LRP_f%0'  ' CBPp300_c%0')  (' LRP_f%0'  ' SKP2%0')  (' LRP_f%0'  ' TP53%0')  (' LRP_f%0'  ' SMAD7%0')  (' LRP_f%0'  ' SMAD6%0')  (' LRP_f%0'  ' DKK_f%0')  (' LRP_f%0'  ' FOXO_f%0')  (' LRP_f%0'  ' TCF7_f%0')  (' LRP_f%0'  ' DKK_g%0')  (' LRP_f%0'  ' MYC%0')  (' LRP_f%0'  ' CCND1%0')  (' LRP_f%0'  ' EGR1%0')  (' LRP_f%0'  ' MMP_f%0')  (' LRP_f%0'  ' PTEN_g%0')  (' LRP_f%0'  ' RTPK_f%0')  (' LRP_f%0'  ' CTNNB1%0')  (' LRP_f%0'  'LEF1%0')  (' LRP_f%0'  'SFRP1%0')  (' LRP_f%0'  'FZD_f%0')  (' LRP_f%0'  ' CASP8%0')  (' LRP_f%0'  ' REL_f%0')  (' LRP_f%0'  ' NFKB_f%0')  (' LRP_f%0'  ' DVL_f%0')  (' LRP_f%0'  ' BTRC%0')  (' LRP_f%0'  ' CK1_f%0')  (' LRP_f%0'  ' AXIN1%0')  (' LRP_f%0'  ' mTORC2_c%0')  (' LRP_f%0'  ' PDPK1%0')  (' LRP_f%0'  ' MEK_f%0')  (' LRP_f%0'  ' CYCS%0')  (' LRP_f%0'  ' CASP9%0')  (' LRP_f%0'  ' GSK3_f%0')  (' LRP_f%0'  ' IRS1%0')  (' LRP_f%0'  ' MDM2%0')  (' LRP_f%0'  ' AKT_f%0')  (' LRP_f%0'  ' BCL2%0')  (' LRP_f%0'  ' RAF_f%0')  (' LRP_f%0'  ' mTORC1_c%0')  (' LRP_f%0'  ' RHEB%0')  (' LRP_f%0'  ' RTPK_g%0')  (' LRP_f%0'  ' PTEN%0')  (' LRP_f%0'  ' CASP3%0')  (' LRP_f%0'  ' PIK3CA%0')  (' LRP_f%0'  ' CREBBP%0')  (' LRP_f%0'  ' PTPN11%0')  (' LRP_f%0'  ' KRAS%0')  (' LRP_f%0'  ' MAP2K4%0')  (' LRP_f%0'  ' MAP2K7%0')  (' LRP_f%0'  ' MAPK14%0')  (' LRP_f%0'  ' JNK_f%0')  (' LRP_f%0'  ' MAP2K3%0')  (' LRP_f%0'  ' ERK_f%0')  (' LRP_f%0'  ' LIF%0')  (' LRP_f%0'  ' PPP1CA%0')  (' LRP_f%0'  ' GAB_f%0')  (' LRP_f%0'  ' SOS1%0')  (' LRP_f%0'  ' PRKCA%0')  (' LRP_f%0'  ' VAV1%0')  (' LRP_f%0'  ' PLCG1%0')  (' LRP_f%0'  ' PRKCD%0')  (' LRP_f%0'  ' RSK_f%0')  (' LRP_f%0'  ' S6K_f%0')  (' LRP_f%0'  ' PLK1%0')  (' LRP_f%0'  ' ILK%0')  (' LRP_f%0'  ' SOCS1%0')  (' LRP_f%0'  ' DUSP6%0')  (' LRP_f%0'  ' STAT3%0')  (' LRP_f%0'  ' LIMK2%0')  (' LRP_f%0'  ' EP300%0')  (' LRP_f%0'  ' STAT1%0')  (' LRP_f%0'  ' IKBKB%0')  (' LRP_f%0'  ' SRF%0')  (' LRP_f%0'  ' PIAS1%0')  (' LRP_f%0'  ' TRAF6%0')  (' LRP_f%0'  ' SOCS1_g%0')  (' LRP_f%0'  ' ISGF3_c%0')  (' LRP_f%0'  ' STAT2%0')  (' LRP_f%0'  ' CFLAR%0')  (' LRP_f%0'  ' SMAD2%0')  (' LRP_f%0'  ' MDM2_g%0')  (' LRP_f%0'  ' BAX%0')  (' LRP_f%0'  ' PRKACA%0')  (' LRP_f%0'  ' TGFB1%0')  (' LRP_f%0'  ' MAP3K8%0')  (' LRP_f%0'  ' TSC_f%0')  (' LRP_f%0'  ' SMAD4%0')  (' LRP_f%0'  ' BAD%0')  (' LRP_f%0'  ' MAP3K5%0')  (' LRP_f%0'  ' AKT1S1%0')  (' LRP_f%0'  ' SKI%0')  (' LRP_f%0'  ' SMAD3%0')  (' LRP_f%0'  ' MAPKAPK2%0')  (' LRP_f%0'  ' DUSP1_g%0')  (' LRP_f%0'  ' MSK_f%0')  (' LRP_f%0'  ' GRAP2%0')  (' LRP_f%0'  ' TAB_f%0')  (' LRP_f%0'  ' ATF2%0')  (' LRP_f%0'  ' SMAD5%0')  (' LRP_f%0'  ' SMAD1%0')  (' LRP_f%0'  ' FOS%0')  (' LRP_f%0'  ' JUN%0')  (' LRP_f%0'  ' MAP3K7%0')  (' LRP_f%0'  ' NLK%0')  (' LRP_f%0'  ' SMAD7_g%0')  (' LRP_f%0'  ' SMAD6_g%0')  (' LRP_f%0'  ' AP1_c%0')  (' LRP_f%0'  ' ACVR1%0')  (' LRP_f%0'  ' PTPN6%0')  (' LRP_f%0'  ' CDC42%0')  (' LRP_f%0'  ' GRB2%0')  (' LRP_f%0'  ' TGFBR1%0')  (' LRP_f%0'  ' SMURF1%0')  (' LRP_f%0'  ' SMURF2%0')  (' LRP_f%0'  ' RHOA%0')  (' LRP_f%0'  ' BMPR2%0')  (' LRP_f%0'  ' PARD6A%0')  (' LRP_f%0'  ' DAAM1%0')  (' LRP_f%0'  ' SFRP1_g%0')  (' LRP_f%0'  ' PPM1A%0')  (' LRP_f%0'  ' CFL_f%0')  (' LRP_f%0'  ' PAK1%0')  (' LRP_f%0'  ' MAP3K11%0')  (' LRP_f%0'  ' MAP3K4%0')  (' LRP_f%0'  ' LIMK1%0')  (' LRP_f%0'  ' ROCK1%0')  (' LRP_f%0'  ' ITCH%0')  (' LRP_f%0'  ' ARHGAP24%0')  (' LRP_f%0'  ' TIAM1%0')  (' LRP_f%0'  ' RND3%0')  (' LRP_f%0'  ' MAPK8IP3%0')  (' LRP_f%0'  ' MXD1%0')  (' LRP_f%0'  ' PIP3%0')  (' BTRC%0'  ' SRC%0')  (' BTRC%0'  ' CSK%0')  (' BTRC%0'  ' CHUK%0')  (' BTRC%0'  ' RAC_f%0')  (' BTRC%0'  ' DUSP1%0')  (' BTRC%0'  ' TGFBR2%0')  (' BTRC%0'  ' ILR_f%0')  (' BTRC%0'  ' SYK%0')  (' BTRC%0'  ' IRAK1%0')  (' BTRC%0'  ' SHC1%0')  (' BTRC%0'  ' JAK_f%0')  (' BTRC%0'  ' CBPp300_c%0')  (' BTRC%0'  ' SKP2%0')  (' BTRC%0'  ' TP53%0')  (' BTRC%0'  ' SMAD7%0')  (' BTRC%0'  ' SMAD6%0')  (' BTRC%0'  ' DKK_f%0')  (' BTRC%0'  ' FOXO_f%0')  (' BTRC%0'  ' TCF7_f%0')  (' BTRC%0'  ' DKK_g%0')  (' BTRC%0'  ' MYC%0')  (' BTRC%0'  ' CCND1%0')  (' BTRC%0'  ' EGR1%0')  (' BTRC%0'  ' MMP_f%0')  (' BTRC%0'  ' PTEN_g%0')  (' BTRC%0'  ' RTPK_f%0')  (' BTRC%0'  ' CTNNB1%0')  (' BTRC%0'  'LEF1%0')  (' BTRC%0'  'SFRP1%0')  (' BTRC%0'  'FZD_f%0')  (' BTRC%0'  ' CASP8%0')  (' BTRC%0'  ' REL_f%0')  (' BTRC%0'  ' NFKB_f%0')  (' BTRC%0'  ' DVL_f%0')  (' BTRC%0'  ' LRP_f%0')  (' BTRC%0'  ' CK1_f%0')  (' BTRC%0'  ' AXIN1%0')  (' BTRC%0'  ' mTORC2_c%0')  (' BTRC%0'  ' PDPK1%0')  (' BTRC%0'  ' MEK_f%0')  (' BTRC%0'  ' CYCS%0')  (' BTRC%0'  ' CASP9%0')  (' BTRC%0'  ' GSK3_f%0')  (' BTRC%0'  ' IRS1%0')  (' BTRC%0'  ' MDM2%0')  (' BTRC%0'  ' AKT_f%0')  (' BTRC%0'  ' BCL2%0')  (' BTRC%0'  ' RAF_f%0')  (' BTRC%0'  ' mTORC1_c%0')  (' BTRC%0'  ' RHEB%0')  (' BTRC%0'  ' RTPK_g%0')  (' BTRC%0'  ' PTEN%0')  (' BTRC%0'  ' CASP3%0')  (' BTRC%0'  ' PIK3CA%0')  (' BTRC%0'  ' CREBBP%0')  (' BTRC%0'  ' PTPN11%0')  (' BTRC%0'  ' KRAS%0')  (' BTRC%0'  ' MAP2K4%0')  (' BTRC%0'  ' MAP2K7%0')  (' BTRC%0'  ' MAPK14%0')  (' BTRC%0'  ' JNK_f%0')  (' BTRC%0'  ' MAP2K3%0')  (' BTRC%0'  ' ERK_f%0')  (' BTRC%0'  ' LIF%0')  (' BTRC%0'  ' PPP1CA%0')  (' BTRC%0'  ' GAB_f%0')  (' BTRC%0'  ' SOS1%0')  (' BTRC%0'  ' PRKCA%0')  (' BTRC%0'  ' VAV1%0')  (' BTRC%0'  ' PLCG1%0')  (' BTRC%0'  ' PRKCD%0')  (' BTRC%0'  ' RSK_f%0')  (' BTRC%0'  ' S6K_f%0')  (' BTRC%0'  ' PLK1%0')  (' BTRC%0'  ' ILK%0')  (' BTRC%0'  ' SOCS1%0')  (' BTRC%0'  ' DUSP6%0')  (' BTRC%0'  ' STAT3%0')  (' BTRC%0'  ' LIMK2%0')  (' BTRC%0'  ' EP300%0')  (' BTRC%0'  ' STAT1%0')  (' BTRC%0'  ' IKBKB%0')  (' BTRC%0'  ' SRF%0')  (' BTRC%0'  ' PIAS1%0')  (' BTRC%0'  ' TRAF6%0')  (' BTRC%0'  ' SOCS1_g%0')  (' BTRC%0'  ' ISGF3_c%0')  (' BTRC%0'  ' STAT2%0')  (' BTRC%0'  ' CFLAR%0')  (' BTRC%0'  ' SMAD2%0')  (' BTRC%0'  ' MDM2_g%0')  (' BTRC%0'  ' BAX%0')  (' BTRC%0'  ' PRKACA%0')  (' BTRC%0'  ' TGFB1%0')  (' BTRC%0'  ' MAP3K8%0')  (' BTRC%0'  ' TSC_f%0')  (' BTRC%0'  ' SMAD4%0')  (' BTRC%0'  ' BAD%0')  (' BTRC%0'  ' MAP3K5%0')  (' BTRC%0'  ' AKT1S1%0')  (' BTRC%0'  ' SKI%0')  (' BTRC%0'  ' SMAD3%0')  (' BTRC%0'  ' MAPKAPK2%0')  (' BTRC%0'  ' DUSP1_g%0')  (' BTRC%0'  ' MSK_f%0')  (' BTRC%0'  ' GRAP2%0')  (' BTRC%0'  ' TAB_f%0')  (' BTRC%0'  ' ATF2%0')  (' BTRC%0'  ' SMAD5%0')  (' BTRC%0'  ' SMAD1%0')  (' BTRC%0'  ' FOS%0')  (' BTRC%0'  ' JUN%0')  (' BTRC%0'  ' MAP3K7%0')  (' BTRC%0'  ' NLK%0')  (' BTRC%0'  ' SMAD7_g%0')  (' BTRC%0'  ' SMAD6_g%0')  (' BTRC%0'  ' AP1_c%0')  (' BTRC%0'  ' ACVR1%0')  (' BTRC%0'  ' PTPN6%0')  (' BTRC%0'  ' CDC42%0')  (' BTRC%0'  ' GRB2%0')  (' BTRC%0'  ' TGFBR1%0')  (' BTRC%0'  ' SMURF1%0')  (' BTRC%0'  ' SMURF2%0')  (' BTRC%0'  ' RHOA%0')  (' BTRC%0'  ' BMPR2%0')  (' BTRC%0'  ' PARD6A%0')  (' BTRC%0'  ' DAAM1%0')  (' BTRC%0'  ' SFRP1_g%0')  (' BTRC%0'  ' PPM1A%0')  (' BTRC%0'  ' CFL_f%0')  (' BTRC%0'  ' PAK1%0')  (' BTRC%0'  ' MAP3K11%0')  (' BTRC%0'  ' MAP3K4%0')  (' BTRC%0'  ' LIMK1%0')  (' BTRC%0'  ' ROCK1%0')  (' BTRC%0'  ' ITCH%0')  (' BTRC%0'  ' ARHGAP24%0')  (' BTRC%0'  ' TIAM1%0')  (' BTRC%0'  ' RND3%0')  (' BTRC%0'  ' MAPK8IP3%0')  (' BTRC%0'  ' MXD1%0')  (' BTRC%0'  ' PIP3%0')  (' CK1_f%0'  ' SRC%0')  (' CK1_f%0'  ' CSK%0')  (' CK1_f%0'  ' CHUK%0')  (' CK1_f%0'  ' RAC_f%0')  (' CK1_f%0'  ' DUSP1%0')  (' CK1_f%0'  ' TGFBR2%0')  (' CK1_f%0'  ' ILR_f%0')  (' CK1_f%0'  ' SYK%0')  (' CK1_f%0'  ' IRAK1%0')  (' CK1_f%0'  ' SHC1%0')  (' CK1_f%0'  ' JAK_f%0')  (' CK1_f%0'  ' CBPp300_c%0')  (' CK1_f%0'  ' SKP2%0')  (' CK1_f%0'  ' TP53%0')  (' CK1_f%0'  ' SMAD7%0')  (' CK1_f%0'  ' SMAD6%0')  (' CK1_f%0'  ' DKK_f%0')  (' CK1_f%0'  ' FOXO_f%0')  (' CK1_f%0'  ' TCF7_f%0')  (' CK1_f%0'  ' DKK_g%0')  (' CK1_f%0'  ' MYC%0')  (' CK1_f%0'  ' CCND1%0')  (' CK1_f%0'  ' EGR1%0')  (' CK1_f%0'  ' MMP_f%0')  (' CK1_f%0'  ' PTEN_g%0')  (' CK1_f%0'  ' RTPK_f%0')  (' CK1_f%0'  ' CTNNB1%0')  (' CK1_f%0'  'LEF1%0')  (' CK1_f%0'  'SFRP1%0')  (' CK1_f%0'  'FZD_f%0')  (' CK1_f%0'  ' CASP8%0')  (' CK1_f%0'  ' REL_f%0')  (' CK1_f%0'  ' NFKB_f%0')  (' CK1_f%0'  ' DVL_f%0')  (' CK1_f%0'  ' LRP_f%0')  (' CK1_f%0'  ' BTRC%0')  (' CK1_f%0'  ' AXIN1%0')  (' CK1_f%0'  ' mTORC2_c%0')  (' CK1_f%0'  ' PDPK1%0')  (' CK1_f%0'  ' MEK_f%0')  (' CK1_f%0'  ' CYCS%0')  (' CK1_f%0'  ' CASP9%0')  (' CK1_f%0'  ' GSK3_f%0')  (' CK1_f%0'  ' IRS1%0')  (' CK1_f%0'  ' MDM2%0')  (' CK1_f%0'  ' AKT_f%0')  (' CK1_f%0'  ' BCL2%0')  (' CK1_f%0'  ' RAF_f%0')  (' CK1_f%0'  ' mTORC1_c%0')  (' CK1_f%0'  ' RHEB%0')  (' CK1_f%0'  ' RTPK_g%0')  (' CK1_f%0'  ' PTEN%0')  (' CK1_f%0'  ' CASP3%0')  (' CK1_f%0'  ' PIK3CA%0')  (' CK1_f%0'  ' CREBBP%0')  (' CK1_f%0'  ' PTPN11%0')  (' CK1_f%0'  ' KRAS%0')  (' CK1_f%0'  ' MAP2K4%0')  (' CK1_f%0'  ' MAP2K7%0')  (' CK1_f%0'  ' MAPK14%0')  (' CK1_f%0'  ' JNK_f%0')  (' CK1_f%0'  ' MAP2K3%0')  (' CK1_f%0'  ' ERK_f%0')  (' CK1_f%0'  ' LIF%0')  (' CK1_f%0'  ' PPP1CA%0')  (' CK1_f%0'  ' GAB_f%0')  (' CK1_f%0'  ' SOS1%0')  (' CK1_f%0'  ' PRKCA%0')  (' CK1_f%0'  ' VAV1%0')  (' CK1_f%0'  ' PLCG1%0')  (' CK1_f%0'  ' PRKCD%0')  (' CK1_f%0'  ' RSK_f%0')  (' CK1_f%0'  ' S6K_f%0')  (' CK1_f%0'  ' PLK1%0')  (' CK1_f%0'  ' ILK%0')  (' CK1_f%0'  ' SOCS1%0')  (' CK1_f%0'  ' DUSP6%0')  (' CK1_f%0'  ' STAT3%0')  (' CK1_f%0'  ' LIMK2%0')  (' CK1_f%0'  ' EP300%0')  (' CK1_f%0'  ' STAT1%0')  (' CK1_f%0'  ' IKBKB%0')  (' CK1_f%0'  ' SRF%0')  (' CK1_f%0'  ' PIAS1%0')  (' CK1_f%0'  ' TRAF6%0')  (' CK1_f%0'  ' SOCS1_g%0')  (' CK1_f%0'  ' ISGF3_c%0')  (' CK1_f%0'  ' STAT2%0')  (' CK1_f%0'  ' CFLAR%0')  (' CK1_f%0'  ' SMAD2%0')  (' CK1_f%0'  ' MDM2_g%0')  (' CK1_f%0'  ' BAX%0')  (' CK1_f%0'  ' PRKACA%0')  (' CK1_f%0'  ' TGFB1%0')  (' CK1_f%0'  ' MAP3K8%0')  (' CK1_f%0'  ' TSC_f%0')  (' CK1_f%0'  ' SMAD4%0')  (' CK1_f%0'  ' BAD%0')  (' CK1_f%0'  ' MAP3K5%0')  (' CK1_f%0'  ' AKT1S1%0')  (' CK1_f%0'  ' SKI%0')  (' CK1_f%0'  ' SMAD3%0')  (' CK1_f%0'  ' MAPKAPK2%0')  (' CK1_f%0'  ' DUSP1_g%0')  (' CK1_f%0'  ' MSK_f%0')  (' CK1_f%0'  ' GRAP2%0')  (' CK1_f%0'  ' TAB_f%0')  (' CK1_f%0'  ' ATF2%0')  (' CK1_f%0'  ' SMAD5%0')  (' CK1_f%0'  ' SMAD1%0')  (' CK1_f%0'  ' FOS%0')  (' CK1_f%0'  ' JUN%0')  (' CK1_f%0'  ' MAP3K7%0')  (' CK1_f%0'  ' NLK%0')  (' CK1_f%0'  ' SMAD7_g%0')  (' CK1_f%0'  ' SMAD6_g%0')  (' CK1_f%0'  ' AP1_c%0')  (' CK1_f%0'  ' ACVR1%0')  (' CK1_f%0'  ' PTPN6%0')  (' CK1_f%0'  ' CDC42%0')  (' CK1_f%0'  ' GRB2%0')  (' CK1_f%0'  ' TGFBR1%0')  (' CK1_f%0'  ' SMURF1%0')  (' CK1_f%0'  ' SMURF2%0')  (' CK1_f%0'  ' RHOA%0')  (' CK1_f%0'  ' BMPR2%0')  (' CK1_f%0'  ' PARD6A%0')  (' CK1_f%0'  ' DAAM1%0')  (' CK1_f%0'  ' SFRP1_g%0')  (' CK1_f%0'  ' PPM1A%0')  (' CK1_f%0'  ' CFL_f%0')  (' CK1_f%0'  ' PAK1%0')  (' CK1_f%0'  ' MAP3K11%0')  (' CK1_f%0'  ' MAP3K4%0')  (' CK1_f%0'  ' LIMK1%0')  (' CK1_f%0'  ' ROCK1%0')  (' CK1_f%0'  ' ITCH%0')  (' CK1_f%0'  ' ARHGAP24%0')  (' CK1_f%0'  ' TIAM1%0')  (' CK1_f%0'  ' RND3%0')  (' CK1_f%0'  ' MAPK8IP3%0')  (' CK1_f%0'  ' MXD1%0')  (' CK1_f%0'  ' PIP3%0')  (' AXIN1%0'  ' SRC%0')  (' AXIN1%0'  ' CSK%0')  (' AXIN1%0'  ' CHUK%0')  (' AXIN1%0'  ' RAC_f%0')  (' AXIN1%0'  ' DUSP1%0')  (' AXIN1%0'  ' TGFBR2%0')  (' AXIN1%0'  ' ILR_f%0')  (' AXIN1%0'  ' SYK%0')  (' AXIN1%0'  ' IRAK1%0')  (' AXIN1%0'  ' SHC1%0')  (' AXIN1%0'  ' JAK_f%0')  (' AXIN1%0'  ' CBPp300_c%0')  (' AXIN1%0'  ' SKP2%0')  (' AXIN1%0'  ' TP53%0')  (' AXIN1%0'  ' SMAD7%0')  (' AXIN1%0'  ' SMAD6%0')  (' AXIN1%0'  ' DKK_f%0')  (' AXIN1%0'  ' FOXO_f%0')  (' AXIN1%0'  ' TCF7_f%0')  (' AXIN1%0'  ' DKK_g%0')  (' AXIN1%0'  ' MYC%0')  (' AXIN1%0'  ' CCND1%0')  (' AXIN1%0'  ' EGR1%0')  (' AXIN1%0'  ' MMP_f%0')  (' AXIN1%0'  ' PTEN_g%0')  (' AXIN1%0'  ' RTPK_f%0')  (' AXIN1%0'  ' CTNNB1%0')  (' AXIN1%0'  'LEF1%0')  (' AXIN1%0'  'SFRP1%0')  (' AXIN1%0'  'FZD_f%0')  (' AXIN1%0'  ' CASP8%0')  (' AXIN1%0'  ' REL_f%0')  (' AXIN1%0'  ' NFKB_f%0')  (' AXIN1%0'  ' DVL_f%0')  (' AXIN1%0'  ' LRP_f%0')  (' AXIN1%0'  ' BTRC%0')  (' AXIN1%0'  ' CK1_f%0')  (' AXIN1%0'  ' mTORC2_c%0')  (' AXIN1%0'  ' PDPK1%0')  (' AXIN1%0'  ' MEK_f%0')  (' AXIN1%0'  ' CYCS%0')  (' AXIN1%0'  ' CASP9%0')  (' AXIN1%0'  ' GSK3_f%0')  (' AXIN1%0'  ' IRS1%0')  (' AXIN1%0'  ' MDM2%0')  (' AXIN1%0'  ' AKT_f%0')  (' AXIN1%0'  ' BCL2%0')  (' AXIN1%0'  ' RAF_f%0')  (' AXIN1%0'  ' mTORC1_c%0')  (' AXIN1%0'  ' RHEB%0')  (' AXIN1%0'  ' RTPK_g%0')  (' AXIN1%0'  ' PTEN%0')  (' AXIN1%0'  ' CASP3%0')  (' AXIN1%0'  ' PIK3CA%0')  (' AXIN1%0'  ' CREBBP%0')  (' AXIN1%0'  ' PTPN11%0')  (' AXIN1%0'  ' KRAS%0')  (' AXIN1%0'  ' MAP2K4%0')  (' AXIN1%0'  ' MAP2K7%0')  (' AXIN1%0'  ' MAPK14%0')  (' AXIN1%0'  ' JNK_f%0')  (' AXIN1%0'  ' MAP2K3%0')  (' AXIN1%0'  ' ERK_f%0')  (' AXIN1%0'  ' LIF%0')  (' AXIN1%0'  ' PPP1CA%0')  (' AXIN1%0'  ' GAB_f%0')  (' AXIN1%0'  ' SOS1%0')  (' AXIN1%0'  ' PRKCA%0')  (' AXIN1%0'  ' VAV1%0')  (' AXIN1%0'  ' PLCG1%0')  (' AXIN1%0'  ' PRKCD%0')  (' AXIN1%0'  ' RSK_f%0')  (' AXIN1%0'  ' S6K_f%0')  (' AXIN1%0'  ' PLK1%0')  (' AXIN1%0'  ' ILK%0')  (' AXIN1%0'  ' SOCS1%0')  (' AXIN1%0'  ' DUSP6%0')  (' AXIN1%0'  ' STAT3%0')  (' AXIN1%0'  ' LIMK2%0')  (' AXIN1%0'  ' EP300%0')  (' AXIN1%0'  ' STAT1%0')  (' AXIN1%0'  ' IKBKB%0')  (' AXIN1%0'  ' SRF%0')  (' AXIN1%0'  ' PIAS1%0')  (' AXIN1%0'  ' TRAF6%0')  (' AXIN1%0'  ' SOCS1_g%0')  (' AXIN1%0'  ' ISGF3_c%0')  (' AXIN1%0'  ' STAT2%0')  (' AXIN1%0'  ' CFLAR%0')  (' AXIN1%0'  ' SMAD2%0')  (' AXIN1%0'  ' MDM2_g%0')  (' AXIN1%0'  ' BAX%0')  (' AXIN1%0'  ' PRKACA%0')  (' AXIN1%0'  ' TGFB1%0')  (' AXIN1%0'  ' MAP3K8%0')  (' AXIN1%0'  ' TSC_f%0')  (' AXIN1%0'  ' SMAD4%0')  (' AXIN1%0'  ' BAD%0')  (' AXIN1%0'  ' MAP3K5%0')  (' AXIN1%0'  ' AKT1S1%0')  (' AXIN1%0'  ' SKI%0')  (' AXIN1%0'  ' SMAD3%0')  (' AXIN1%0'  ' MAPKAPK2%0')  (' AXIN1%0'  ' DUSP1_g%0')  (' AXIN1%0'  ' MSK_f%0')  (' AXIN1%0'  ' GRAP2%0')  (' AXIN1%0'  ' TAB_f%0')  (' AXIN1%0'  ' ATF2%0')  (' AXIN1%0'  ' SMAD5%0')  (' AXIN1%0'  ' SMAD1%0')  (' AXIN1%0'  ' FOS%0')  (' AXIN1%0'  ' JUN%0')  (' AXIN1%0'  ' MAP3K7%0')  (' AXIN1%0'  ' NLK%0')  (' AXIN1%0'  ' SMAD7_g%0')  (' AXIN1%0'  ' SMAD6_g%0')  (' AXIN1%0'  ' AP1_c%0')  (' AXIN1%0'  ' ACVR1%0')  (' AXIN1%0'  ' PTPN6%0')  (' AXIN1%0'  ' CDC42%0')  (' AXIN1%0'  ' GRB2%0')  (' AXIN1%0'  ' TGFBR1%0')  (' AXIN1%0'  ' SMURF1%0')  (' AXIN1%0'  ' SMURF2%0')  (' AXIN1%0'  ' RHOA%0')  (' AXIN1%0'  ' BMPR2%0')  (' AXIN1%0'  ' PARD6A%0')  (' AXIN1%0'  ' DAAM1%0')  (' AXIN1%0'  ' SFRP1_g%0')  (' AXIN1%0'  ' PPM1A%0')  (' AXIN1%0'  ' CFL_f%0')  (' AXIN1%0'  ' PAK1%0')  (' AXIN1%0'  ' MAP3K11%0')  (' AXIN1%0'  ' MAP3K4%0')  (' AXIN1%0'  ' LIMK1%0')  (' AXIN1%0'  ' ROCK1%0')  (' AXIN1%0'  ' ITCH%0')  (' AXIN1%0'  ' ARHGAP24%0')  (' AXIN1%0'  ' TIAM1%0')  (' AXIN1%0'  ' RND3%0')  (' AXIN1%0'  ' MAPK8IP3%0')  (' AXIN1%0'  ' MXD1%0')  (' AXIN1%0'  ' PIP3%0')  (' mTORC2_c%0'  ' SRC%0')  (' mTORC2_c%0'  ' CSK%0')  (' mTORC2_c%0'  ' CHUK%0')  (' mTORC2_c%0'  ' RAC_f%0')  (' mTORC2_c%0'  ' DUSP1%0')  (' mTORC2_c%0'  ' TGFBR2%0')  (' mTORC2_c%0'  ' ILR_f%0')  (' mTORC2_c%0'  ' SYK%0')  (' mTORC2_c%0'  ' IRAK1%0')  (' mTORC2_c%0'  ' SHC1%0')  (' mTORC2_c%0'  ' JAK_f%0')  (' mTORC2_c%0'  ' CBPp300_c%0')  (' mTORC2_c%0'  ' SKP2%0')  (' mTORC2_c%0'  ' TP53%0')  (' mTORC2_c%0'  ' SMAD7%0')  (' mTORC2_c%0'  ' SMAD6%0')  (' mTORC2_c%0'  ' DKK_f%0')  (' mTORC2_c%0'  ' FOXO_f%0')  (' mTORC2_c%0'  ' TCF7_f%0')  (' mTORC2_c%0'  ' DKK_g%0')  (' mTORC2_c%0'  ' MYC%0')  (' mTORC2_c%0'  ' CCND1%0')  (' mTORC2_c%0'  ' EGR1%0')  (' mTORC2_c%0'  ' MMP_f%0')  (' mTORC2_c%0'  ' PTEN_g%0')  (' mTORC2_c%0'  ' RTPK_f%0')  (' mTORC2_c%0'  ' CTNNB1%0')  (' mTORC2_c%0'  'LEF1%0')  (' mTORC2_c%0'  'SFRP1%0')  (' mTORC2_c%0'  'FZD_f%0')  (' mTORC2_c%0'  ' CASP8%0')  (' mTORC2_c%0'  ' REL_f%0')  (' mTORC2_c%0'  ' NFKB_f%0')  (' mTORC2_c%0'  ' DVL_f%0')  (' mTORC2_c%0'  ' LRP_f%0')  (' mTORC2_c%0'  ' BTRC%0')  (' mTORC2_c%0'  ' CK1_f%0')  (' mTORC2_c%0'  ' AXIN1%0')  (' mTORC2_c%0'  ' PDPK1%0')  (' mTORC2_c%0'  ' MEK_f%0')  (' mTORC2_c%0'  ' CYCS%0')  (' mTORC2_c%0'  ' CASP9%0')  (' mTORC2_c%0'  ' GSK3_f%0')  (' mTORC2_c%0'  ' IRS1%0')  (' mTORC2_c%0'  ' MDM2%0')  (' mTORC2_c%0'  ' AKT_f%0')  (' mTORC2_c%0'  ' BCL2%0')  (' mTORC2_c%0'  ' RAF_f%0')  (' mTORC2_c%0'  ' mTORC1_c%0')  (' mTORC2_c%0'  ' RHEB%0')  (' mTORC2_c%0'  ' RTPK_g%0')  (' mTORC2_c%0'  ' PTEN%0')  (' mTORC2_c%0'  ' CASP3%0')  (' mTORC2_c%0'  ' PIK3CA%0')  (' mTORC2_c%0'  ' CREBBP%0')  (' mTORC2_c%0'  ' PTPN11%0')  (' mTORC2_c%0'  ' KRAS%0')  (' mTORC2_c%0'  ' MAP2K4%0')  (' mTORC2_c%0'  ' MAP2K7%0')  (' mTORC2_c%0'  ' MAPK14%0')  (' mTORC2_c%0'  ' JNK_f%0')  (' mTORC2_c%0'  ' MAP2K3%0')  (' mTORC2_c%0'  ' ERK_f%0')  (' mTORC2_c%0'  ' LIF%0')  (' mTORC2_c%0'  ' PPP1CA%0')  (' mTORC2_c%0'  ' GAB_f%0')  (' mTORC2_c%0'  ' SOS1%0')  (' mTORC2_c%0'  ' PRKCA%0')  (' mTORC2_c%0'  ' VAV1%0')  (' mTORC2_c%0'  ' PLCG1%0')  (' mTORC2_c%0'  ' PRKCD%0')  (' mTORC2_c%0'  ' RSK_f%0')  (' mTORC2_c%0'  ' S6K_f%0')  (' mTORC2_c%0'  ' PLK1%0')  (' mTORC2_c%0'  ' ILK%0')  (' mTORC2_c%0'  ' SOCS1%0')  (' mTORC2_c%0'  ' DUSP6%0')  (' mTORC2_c%0'  ' STAT3%0')  (' mTORC2_c%0'  ' LIMK2%0')  (' mTORC2_c%0'  ' EP300%0')  (' mTORC2_c%0'  ' STAT1%0')  (' mTORC2_c%0'  ' IKBKB%0')  (' mTORC2_c%0'  ' SRF%0')  (' mTORC2_c%0'  ' PIAS1%0')  (' mTORC2_c%0'  ' TRAF6%0')  (' mTORC2_c%0'  ' SOCS1_g%0')  (' mTORC2_c%0'  ' ISGF3_c%0')  (' mTORC2_c%0'  ' STAT2%0')  (' mTORC2_c%0'  ' CFLAR%0')  (' mTORC2_c%0'  ' SMAD2%0')  (' mTORC2_c%0'  ' MDM2_g%0')  (' mTORC2_c%0'  ' BAX%0')  (' mTORC2_c%0'  ' PRKACA%0')  (' mTORC2_c%0'  ' TGFB1%0')  (' mTORC2_c%0'  ' MAP3K8%0')  (' mTORC2_c%0'  ' TSC_f%0')  (' mTORC2_c%0'  ' SMAD4%0')  (' mTORC2_c%0'  ' BAD%0')  (' mTORC2_c%0'  ' MAP3K5%0')  (' mTORC2_c%0'  ' AKT1S1%0')  (' mTORC2_c%0'  ' SKI%0')  (' mTORC2_c%0'  ' SMAD3%0')  (' mTORC2_c%0'  ' MAPKAPK2%0')  (' mTORC2_c%0'  ' DUSP1_g%0')  (' mTORC2_c%0'  ' MSK_f%0')  (' mTORC2_c%0'  ' GRAP2%0')  (' mTORC2_c%0'  ' TAB_f%0')  (' mTORC2_c%0'  ' ATF2%0')  (' mTORC2_c%0'  ' SMAD5%0')  (' mTORC2_c%0'  ' SMAD1%0')  (' mTORC2_c%0'  ' FOS%0')  (' mTORC2_c%0'  ' JUN%0')  (' mTORC2_c%0'  ' MAP3K7%0')  (' mTORC2_c%0'  ' NLK%0')  (' mTORC2_c%0'  ' SMAD7_g%0')  (' mTORC2_c%0'  ' SMAD6_g%0')  (' mTORC2_c%0'  ' AP1_c%0')  (' mTORC2_c%0'  ' ACVR1%0')  (' mTORC2_c%0'  ' PTPN6%0')  (' mTORC2_c%0'  ' CDC42%0')  (' mTORC2_c%0'  ' GRB2%0')  (' mTORC2_c%0'  ' TGFBR1%0')  (' mTORC2_c%0'  ' SMURF1%0')  (' mTORC2_c%0'  ' SMURF2%0')  (' mTORC2_c%0'  ' RHOA%0')  (' mTORC2_c%0'  ' BMPR2%0')  (' mTORC2_c%0'  ' PARD6A%0')  (' mTORC2_c%0'  ' DAAM1%0')  (' mTORC2_c%0'  ' SFRP1_g%0')  (' mTORC2_c%0'  ' PPM1A%0')  (' mTORC2_c%0'  ' CFL_f%0')  (' mTORC2_c%0'  ' PAK1%0')  (' mTORC2_c%0'  ' MAP3K11%0')  (' mTORC2_c%0'  ' MAP3K4%0')  (' mTORC2_c%0'  ' LIMK1%0')  (' mTORC2_c%0'  ' ROCK1%0')  (' mTORC2_c%0'  ' ITCH%0')  (' mTORC2_c%0'  ' ARHGAP24%0')  (' mTORC2_c%0'  ' TIAM1%0')  (' mTORC2_c%0'  ' RND3%0')  (' mTORC2_c%0'  ' MAPK8IP3%0')  (' mTORC2_c%0'  ' MXD1%0')  (' mTORC2_c%0'  ' PIP3%0')  (' PDPK1%0'  ' SRC%0')  (' PDPK1%0'  ' CSK%0')  (' PDPK1%0'  ' CHUK%0')  (' PDPK1%0'  ' RAC_f%0')  (' PDPK1%0'  ' DUSP1%0')  (' PDPK1%0'  ' TGFBR2%0')  (' PDPK1%0'  ' ILR_f%0')  (' PDPK1%0'  ' SYK%0')  (' PDPK1%0'  ' IRAK1%0')  (' PDPK1%0'  ' SHC1%0')  (' PDPK1%0'  ' JAK_f%0')  (' PDPK1%0'  ' CBPp300_c%0')  (' PDPK1%0'  ' SKP2%0')  (' PDPK1%0'  ' TP53%0')  (' PDPK1%0'  ' SMAD7%0')  (' PDPK1%0'  ' SMAD6%0')  (' PDPK1%0'  ' DKK_f%0')  (' PDPK1%0'  ' FOXO_f%0')  (' PDPK1%0'  ' TCF7_f%0')  (' PDPK1%0'  ' DKK_g%0')  (' PDPK1%0'  ' MYC%0')  (' PDPK1%0'  ' CCND1%0')  (' PDPK1%0'  ' EGR1%0')  (' PDPK1%0'  ' MMP_f%0')  (' PDPK1%0'  ' PTEN_g%0')  (' PDPK1%0'  ' RTPK_f%0')  (' PDPK1%0'  ' CTNNB1%0')  (' PDPK1%0'  'LEF1%0')  (' PDPK1%0'  'SFRP1%0')  (' PDPK1%0'  'FZD_f%0')  (' PDPK1%0'  ' CASP8%0')  (' PDPK1%0'  ' REL_f%0')  (' PDPK1%0'  ' NFKB_f%0')  (' PDPK1%0'  ' DVL_f%0')  (' PDPK1%0'  ' LRP_f%0')  (' PDPK1%0'  ' BTRC%0')  (' PDPK1%0'  ' CK1_f%0')  (' PDPK1%0'  ' AXIN1%0')  (' PDPK1%0'  ' mTORC2_c%0')  (' PDPK1%0'  ' MEK_f%0')  (' PDPK1%0'  ' CYCS%0')  (' PDPK1%0'  ' CASP9%0')  (' PDPK1%0'  ' GSK3_f%0')  (' PDPK1%0'  ' IRS1%0')  (' PDPK1%0'  ' MDM2%0')  (' PDPK1%0'  ' AKT_f%0')  (' PDPK1%0'  ' BCL2%0')  (' PDPK1%0'  ' RAF_f%0')  (' PDPK1%0'  ' mTORC1_c%0')  (' PDPK1%0'  ' RHEB%0')  (' PDPK1%0'  ' RTPK_g%0')  (' PDPK1%0'  ' PTEN%0')  (' PDPK1%0'  ' CASP3%0')  (' PDPK1%0'  ' PIK3CA%0')  (' PDPK1%0'  ' CREBBP%0')  (' PDPK1%0'  ' PTPN11%0')  (' PDPK1%0'  ' KRAS%0')  (' PDPK1%0'  ' MAP2K4%0')  (' PDPK1%0'  ' MAP2K7%0')  (' PDPK1%0'  ' MAPK14%0')  (' PDPK1%0'  ' JNK_f%0')  (' PDPK1%0'  ' MAP2K3%0')  (' PDPK1%0'  ' ERK_f%0')  (' PDPK1%0'  ' LIF%0')  (' PDPK1%0'  ' PPP1CA%0')  (' PDPK1%0'  ' GAB_f%0')  (' PDPK1%0'  ' SOS1%0')  (' PDPK1%0'  ' PRKCA%0')  (' PDPK1%0'  ' VAV1%0')  (' PDPK1%0'  ' PLCG1%0')  (' PDPK1%0'  ' PRKCD%0')  (' PDPK1%0'  ' RSK_f%0')  (' PDPK1%0'  ' S6K_f%0')  (' PDPK1%0'  ' PLK1%0')  (' PDPK1%0'  ' ILK%0')  (' PDPK1%0'  ' SOCS1%0')  (' PDPK1%0'  ' DUSP6%0')  (' PDPK1%0'  ' STAT3%0')  (' PDPK1%0'  ' LIMK2%0')  (' PDPK1%0'  ' EP300%0')  (' PDPK1%0'  ' STAT1%0')  (' PDPK1%0'  ' IKBKB%0')  (' PDPK1%0'  ' SRF%0')  (' PDPK1%0'  ' PIAS1%0')  (' PDPK1%0'  ' TRAF6%0')  (' PDPK1%0'  ' SOCS1_g%0')  (' PDPK1%0'  ' ISGF3_c%0')  (' PDPK1%0'  ' STAT2%0')  (' PDPK1%0'  ' CFLAR%0')  (' PDPK1%0'  ' SMAD2%0')  (' PDPK1%0'  ' MDM2_g%0')  (' PDPK1%0'  ' BAX%0')  (' PDPK1%0'  ' PRKACA%0')  (' PDPK1%0'  ' TGFB1%0')  (' PDPK1%0'  ' MAP3K8%0')  (' PDPK1%0'  ' TSC_f%0')  (' PDPK1%0'  ' SMAD4%0')  (' PDPK1%0'  ' BAD%0')  (' PDPK1%0'  ' MAP3K5%0')  (' PDPK1%0'  ' AKT1S1%0')  (' PDPK1%0'  ' SKI%0')  (' PDPK1%0'  ' SMAD3%0')  (' PDPK1%0'  ' MAPKAPK2%0')  (' PDPK1%0'  ' DUSP1_g%0')  (' PDPK1%0'  ' MSK_f%0')  (' PDPK1%0'  ' GRAP2%0')  (' PDPK1%0'  ' TAB_f%0')  (' PDPK1%0'  ' ATF2%0')  (' PDPK1%0'  ' SMAD5%0')  (' PDPK1%0'  ' SMAD1%0')  (' PDPK1%0'  ' FOS%0')  (' PDPK1%0'  ' JUN%0')  (' PDPK1%0'  ' MAP3K7%0')  (' PDPK1%0'  ' NLK%0')  (' PDPK1%0'  ' SMAD7_g%0')  (' PDPK1%0'  ' SMAD6_g%0')  (' PDPK1%0'  ' AP1_c%0')  (' PDPK1%0'  ' ACVR1%0')  (' PDPK1%0'  ' PTPN6%0')  (' PDPK1%0'  ' CDC42%0')  (' PDPK1%0'  ' GRB2%0')  (' PDPK1%0'  ' TGFBR1%0')  (' PDPK1%0'  ' SMURF1%0')  (' PDPK1%0'  ' SMURF2%0')  (' PDPK1%0'  ' RHOA%0')  (' PDPK1%0'  ' BMPR2%0')  (' PDPK1%0'  ' PARD6A%0')  (' PDPK1%0'  ' DAAM1%0')  (' PDPK1%0'  ' SFRP1_g%0')  (' PDPK1%0'  ' PPM1A%0')  (' PDPK1%0'  ' CFL_f%0')  (' PDPK1%0'  ' PAK1%0')  (' PDPK1%0'  ' MAP3K11%0')  (' PDPK1%0'  ' MAP3K4%0')  (' PDPK1%0'  ' LIMK1%0')  (' PDPK1%0'  ' ROCK1%0')  (' PDPK1%0'  ' ITCH%0')  (' PDPK1%0'  ' ARHGAP24%0')  (' PDPK1%0'  ' TIAM1%0')  (' PDPK1%0'  ' RND3%0')  (' PDPK1%0'  ' MAPK8IP3%0')  (' PDPK1%0'  ' MXD1%0')  (' PDPK1%0'  ' PIP3%0')  (' MEK_f%0'  ' SRC%0')  (' MEK_f%0'  ' CSK%0')  (' MEK_f%0'  ' CHUK%0')  (' MEK_f%0'  ' RAC_f%0')  (' MEK_f%0'  ' DUSP1%0')  (' MEK_f%0'  ' TGFBR2%0')  (' MEK_f%0'  ' ILR_f%0')  (' MEK_f%0'  ' SYK%0')  (' MEK_f%0'  ' IRAK1%0')  (' MEK_f%0'  ' SHC1%0')  (' MEK_f%0'  ' JAK_f%0')  (' MEK_f%0'  ' CBPp300_c%0')  (' MEK_f%0'  ' SKP2%0')  (' MEK_f%0'  ' TP53%0')  (' MEK_f%0'  ' SMAD7%0')  (' MEK_f%0'  ' SMAD6%0')  (' MEK_f%0'  ' DKK_f%0')  (' MEK_f%0'  ' FOXO_f%0')  (' MEK_f%0'  ' TCF7_f%0')  (' MEK_f%0'  ' DKK_g%0')  (' MEK_f%0'  ' MYC%0')  (' MEK_f%0'  ' CCND1%0')  (' MEK_f%0'  ' EGR1%0')  (' MEK_f%0'  ' MMP_f%0')  (' MEK_f%0'  ' PTEN_g%0')  (' MEK_f%0'  ' RTPK_f%0')  (' MEK_f%0'  ' CTNNB1%0')  (' MEK_f%0'  'LEF1%0')  (' MEK_f%0'  'SFRP1%0')  (' MEK_f%0'  'FZD_f%0')  (' MEK_f%0'  ' CASP8%0')  (' MEK_f%0'  ' REL_f%0')  (' MEK_f%0'  ' NFKB_f%0')  (' MEK_f%0'  ' DVL_f%0')  (' MEK_f%0'  ' LRP_f%0')  (' MEK_f%0'  ' BTRC%0')  (' MEK_f%0'  ' CK1_f%0')  (' MEK_f%0'  ' AXIN1%0')  (' MEK_f%0'  ' mTORC2_c%0')  (' MEK_f%0'  ' PDPK1%0')  (' MEK_f%0'  ' CYCS%0')  (' MEK_f%0'  ' CASP9%0')  (' MEK_f%0'  ' GSK3_f%0')  (' MEK_f%0'  ' IRS1%0')  (' MEK_f%0'  ' MDM2%0')  (' MEK_f%0'  ' AKT_f%0')  (' MEK_f%0'  ' BCL2%0')  (' MEK_f%0'  ' RAF_f%0')  (' MEK_f%0'  ' mTORC1_c%0')  (' MEK_f%0'  ' RHEB%0')  (' MEK_f%0'  ' RTPK_g%0')  (' MEK_f%0'  ' PTEN%0')  (' MEK_f%0'  ' CASP3%0')  (' MEK_f%0'  ' PIK3CA%0')  (' MEK_f%0'  ' CREBBP%0')  (' MEK_f%0'  ' PTPN11%0')  (' MEK_f%0'  ' KRAS%0')  (' MEK_f%0'  ' MAP2K4%0')  (' MEK_f%0'  ' MAP2K7%0')  (' MEK_f%0'  ' MAPK14%0')  (' MEK_f%0'  ' JNK_f%0')  (' MEK_f%0'  ' MAP2K3%0')  (' MEK_f%0'  ' ERK_f%0')  (' MEK_f%0'  ' LIF%0')  (' MEK_f%0'  ' PPP1CA%0')  (' MEK_f%0'  ' GAB_f%0')  (' MEK_f%0'  ' SOS1%0')  (' MEK_f%0'  ' PRKCA%0')  (' MEK_f%0'  ' VAV1%0')  (' MEK_f%0'  ' PLCG1%0')  (' MEK_f%0'  ' PRKCD%0')  (' MEK_f%0'  ' RSK_f%0')  (' MEK_f%0'  ' S6K_f%0')  (' MEK_f%0'  ' PLK1%0')  (' MEK_f%0'  ' ILK%0')  (' MEK_f%0'  ' SOCS1%0')  (' MEK_f%0'  ' DUSP6%0')  (' MEK_f%0'  ' STAT3%0')  (' MEK_f%0'  ' LIMK2%0')  (' MEK_f%0'  ' EP300%0')  (' MEK_f%0'  ' STAT1%0')  (' MEK_f%0'  ' IKBKB%0')  (' MEK_f%0'  ' SRF%0')  (' MEK_f%0'  ' PIAS1%0')  (' MEK_f%0'  ' TRAF6%0')  (' MEK_f%0'  ' SOCS1_g%0')  (' MEK_f%0'  ' ISGF3_c%0')  (' MEK_f%0'  ' STAT2%0')  (' MEK_f%0'  ' CFLAR%0')  (' MEK_f%0'  ' SMAD2%0')  (' MEK_f%0'  ' MDM2_g%0')  (' MEK_f%0'  ' BAX%0')  (' MEK_f%0'  ' PRKACA%0')  (' MEK_f%0'  ' TGFB1%0')  (' MEK_f%0'  ' MAP3K8%0')  (' MEK_f%0'  ' TSC_f%0')  (' MEK_f%0'  ' SMAD4%0')  (' MEK_f%0'  ' BAD%0')  (' MEK_f%0'  ' MAP3K5%0')  (' MEK_f%0'  ' AKT1S1%0')  (' MEK_f%0'  ' SKI%0')  (' MEK_f%0'  ' SMAD3%0')  (' MEK_f%0'  ' MAPKAPK2%0')  (' MEK_f%0'  ' DUSP1_g%0')  (' MEK_f%0'  ' MSK_f%0')  (' MEK_f%0'  ' GRAP2%0')  (' MEK_f%0'  ' TAB_f%0')  (' MEK_f%0'  ' ATF2%0')  (' MEK_f%0'  ' SMAD5%0')  (' MEK_f%0'  ' SMAD1%0')  (' MEK_f%0'  ' FOS%0')  (' MEK_f%0'  ' JUN%0')  (' MEK_f%0'  ' MAP3K7%0')  (' MEK_f%0'  ' NLK%0')  (' MEK_f%0'  ' SMAD7_g%0')  (' MEK_f%0'  ' SMAD6_g%0')  (' MEK_f%0'  ' AP1_c%0')  (' MEK_f%0'  ' ACVR1%0')  (' MEK_f%0'  ' PTPN6%0')  (' MEK_f%0'  ' CDC42%0')  (' MEK_f%0'  ' GRB2%0')  (' MEK_f%0'  ' TGFBR1%0')  (' MEK_f%0'  ' SMURF1%0')  (' MEK_f%0'  ' SMURF2%0')  (' MEK_f%0'  ' RHOA%0')  (' MEK_f%0'  ' BMPR2%0')  (' MEK_f%0'  ' PARD6A%0')  (' MEK_f%0'  ' DAAM1%0')  (' MEK_f%0'  ' SFRP1_g%0')  (' MEK_f%0'  ' PPM1A%0')  (' MEK_f%0'  ' CFL_f%0')  (' MEK_f%0'  ' PAK1%0')  (' MEK_f%0'  ' MAP3K11%0')  (' MEK_f%0'  ' MAP3K4%0')  (' MEK_f%0'  ' LIMK1%0')  (' MEK_f%0'  ' ROCK1%0')  (' MEK_f%0'  ' ITCH%0')  (' MEK_f%0'  ' ARHGAP24%0')  (' MEK_f%0'  ' TIAM1%0')  (' MEK_f%0'  ' RND3%0')  (' MEK_f%0'  ' MAPK8IP3%0')  (' MEK_f%0'  ' MXD1%0')  (' MEK_f%0'  ' PIP3%0')  (' CYCS%0'  ' SRC%0')  (' CYCS%0'  ' CSK%0')  (' CYCS%0'  ' CHUK%0')  (' CYCS%0'  ' RAC_f%0')  (' CYCS%0'  ' DUSP1%0')  (' CYCS%0'  ' TGFBR2%0')  (' CYCS%0'  ' ILR_f%0')  (' CYCS%0'  ' SYK%0')  (' CYCS%0'  ' IRAK1%0')  (' CYCS%0'  ' SHC1%0')  (' CYCS%0'  ' JAK_f%0')  (' CYCS%0'  ' CBPp300_c%0')  (' CYCS%0'  ' SKP2%0')  (' CYCS%0'  ' TP53%0')  (' CYCS%0'  ' SMAD7%0')  (' CYCS%0'  ' SMAD6%0')  (' CYCS%0'  ' DKK_f%0')  (' CYCS%0'  ' FOXO_f%0')  (' CYCS%0'  ' TCF7_f%0')  (' CYCS%0'  ' DKK_g%0')  (' CYCS%0'  ' MYC%0')  (' CYCS%0'  ' CCND1%0')  (' CYCS%0'  ' EGR1%0')  (' CYCS%0'  ' MMP_f%0')  (' CYCS%0'  ' PTEN_g%0')  (' CYCS%0'  ' RTPK_f%0')  (' CYCS%0'  ' CTNNB1%0')  (' CYCS%0'  'LEF1%0')  (' CYCS%0'  'SFRP1%0')  (' CYCS%0'  'FZD_f%0')  (' CYCS%0'  ' CASP8%0')  (' CYCS%0'  ' REL_f%0')  (' CYCS%0'  ' NFKB_f%0')  (' CYCS%0'  ' DVL_f%0')  (' CYCS%0'  ' LRP_f%0')  (' CYCS%0'  ' BTRC%0')  (' CYCS%0'  ' CK1_f%0')  (' CYCS%0'  ' AXIN1%0')  (' CYCS%0'  ' mTORC2_c%0')  (' CYCS%0'  ' PDPK1%0')  (' CYCS%0'  ' MEK_f%0')  (' CYCS%0'  ' CASP9%0')  (' CYCS%0'  ' GSK3_f%0')  (' CYCS%0'  ' IRS1%0')  (' CYCS%0'  ' MDM2%0')  (' CYCS%0'  ' AKT_f%0')  (' CYCS%0'  ' BCL2%0')  (' CYCS%0'  ' RAF_f%0')  (' CYCS%0'  ' mTORC1_c%0')  (' CYCS%0'  ' RHEB%0')  (' CYCS%0'  ' RTPK_g%0')  (' CYCS%0'  ' PTEN%0')  (' CYCS%0'  ' CASP3%0')  (' CYCS%0'  ' PIK3CA%0')  (' CYCS%0'  ' CREBBP%0')  (' CYCS%0'  ' PTPN11%0')  (' CYCS%0'  ' KRAS%0')  (' CYCS%0'  ' MAP2K4%0')  (' CYCS%0'  ' MAP2K7%0')  (' CYCS%0'  ' MAPK14%0')  (' CYCS%0'  ' JNK_f%0')  (' CYCS%0'  ' MAP2K3%0')  (' CYCS%0'  ' ERK_f%0')  (' CYCS%0'  ' LIF%0')  (' CYCS%0'  ' PPP1CA%0')  (' CYCS%0'  ' GAB_f%0')  (' CYCS%0'  ' SOS1%0')  (' CYCS%0'  ' PRKCA%0')  (' CYCS%0'  ' VAV1%0')  (' CYCS%0'  ' PLCG1%0')  (' CYCS%0'  ' PRKCD%0')  (' CYCS%0'  ' RSK_f%0')  (' CYCS%0'  ' S6K_f%0')  (' CYCS%0'  ' PLK1%0')  (' CYCS%0'  ' ILK%0')  (' CYCS%0'  ' SOCS1%0')  (' CYCS%0'  ' DUSP6%0')  (' CYCS%0'  ' STAT3%0')  (' CYCS%0'  ' LIMK2%0')  (' CYCS%0'  ' EP300%0')  (' CYCS%0'  ' STAT1%0')  (' CYCS%0'  ' IKBKB%0')  (' CYCS%0'  ' SRF%0')  (' CYCS%0'  ' PIAS1%0')  (' CYCS%0'  ' TRAF6%0')  (' CYCS%0'  ' SOCS1_g%0')  (' CYCS%0'  ' ISGF3_c%0')  (' CYCS%0'  ' STAT2%0')  (' CYCS%0'  ' CFLAR%0')  (' CYCS%0'  ' SMAD2%0')  (' CYCS%0'  ' MDM2_g%0')  (' CYCS%0'  ' BAX%0')  (' CYCS%0'  ' PRKACA%0')  (' CYCS%0'  ' TGFB1%0')  (' CYCS%0'  ' MAP3K8%0')  (' CYCS%0'  ' TSC_f%0')  (' CYCS%0'  ' SMAD4%0')  (' CYCS%0'  ' BAD%0')  (' CYCS%0'  ' MAP3K5%0')  (' CYCS%0'  ' AKT1S1%0')  (' CYCS%0'  ' SKI%0')  (' CYCS%0'  ' SMAD3%0')  (' CYCS%0'  ' MAPKAPK2%0')  (' CYCS%0'  ' DUSP1_g%0')  (' CYCS%0'  ' MSK_f%0')  (' CYCS%0'  ' GRAP2%0')  (' CYCS%0'  ' TAB_f%0')  (' CYCS%0'  ' ATF2%0')  (' CYCS%0'  ' SMAD5%0')  (' CYCS%0'  ' SMAD1%0')  (' CYCS%0'  ' FOS%0')  (' CYCS%0'  ' JUN%0')  (' CYCS%0'  ' MAP3K7%0')  (' CYCS%0'  ' NLK%0')  (' CYCS%0'  ' SMAD7_g%0')  (' CYCS%0'  ' SMAD6_g%0')  (' CYCS%0'  ' AP1_c%0')  (' CYCS%0'  ' ACVR1%0')  (' CYCS%0'  ' PTPN6%0')  (' CYCS%0'  ' CDC42%0')  (' CYCS%0'  ' GRB2%0')  (' CYCS%0'  ' TGFBR1%0')  (' CYCS%0'  ' SMURF1%0')  (' CYCS%0'  ' SMURF2%0')  (' CYCS%0'  ' RHOA%0')  (' CYCS%0'  ' BMPR2%0')  (' CYCS%0'  ' PARD6A%0')  (' CYCS%0'  ' DAAM1%0')  (' CYCS%0'  ' SFRP1_g%0')  (' CYCS%0'  ' PPM1A%0')  (' CYCS%0'  ' CFL_f%0')  (' CYCS%0'  ' PAK1%0')  (' CYCS%0'  ' MAP3K11%0')  (' CYCS%0'  ' MAP3K4%0')  (' CYCS%0'  ' LIMK1%0')  (' CYCS%0'  ' ROCK1%0')  (' CYCS%0'  ' ITCH%0')  (' CYCS%0'  ' ARHGAP24%0')  (' CYCS%0'  ' TIAM1%0')  (' CYCS%0'  ' RND3%0')  (' CYCS%0'  ' MAPK8IP3%0')  (' CYCS%0'  ' MXD1%0')  (' CYCS%0'  ' PIP3%0')  (' CASP9%0'  ' SRC%0')  (' CASP9%0'  ' CSK%0')  (' CASP9%0'  ' CHUK%0')  (' CASP9%0'  ' RAC_f%0')  (' CASP9%0'  ' DUSP1%0')  (' CASP9%0'  ' TGFBR2%0')  (' CASP9%0'  ' ILR_f%0')  (' CASP9%0'  ' SYK%0')  (' CASP9%0'  ' IRAK1%0')  (' CASP9%0'  ' SHC1%0')  (' CASP9%0'  ' JAK_f%0')  (' CASP9%0'  ' CBPp300_c%0')  (' CASP9%0'  ' SKP2%0')  (' CASP9%0'  ' TP53%0')  (' CASP9%0'  ' SMAD7%0')  (' CASP9%0'  ' SMAD6%0')  (' CASP9%0'  ' DKK_f%0')  (' CASP9%0'  ' FOXO_f%0')  (' CASP9%0'  ' TCF7_f%0')  (' CASP9%0'  ' DKK_g%0')  (' CASP9%0'  ' MYC%0')  (' CASP9%0'  ' CCND1%0')  (' CASP9%0'  ' EGR1%0')  (' CASP9%0'  ' MMP_f%0')  (' CASP9%0'  ' PTEN_g%0')  (' CASP9%0'  ' RTPK_f%0')  (' CASP9%0'  ' CTNNB1%0')  (' CASP9%0'  'LEF1%0')  (' CASP9%0'  'SFRP1%0')  (' CASP9%0'  'FZD_f%0')  (' CASP9%0'  ' CASP8%0')  (' CASP9%0'  ' REL_f%0')  (' CASP9%0'  ' NFKB_f%0')  (' CASP9%0'  ' DVL_f%0')  (' CASP9%0'  ' LRP_f%0')  (' CASP9%0'  ' BTRC%0')  (' CASP9%0'  ' CK1_f%0')  (' CASP9%0'  ' AXIN1%0')  (' CASP9%0'  ' mTORC2_c%0')  (' CASP9%0'  ' PDPK1%0')  (' CASP9%0'  ' MEK_f%0')  (' CASP9%0'  ' CYCS%0')  (' CASP9%0'  ' GSK3_f%0')  (' CASP9%0'  ' IRS1%0')  (' CASP9%0'  ' MDM2%0')  (' CASP9%0'  ' AKT_f%0')  (' CASP9%0'  ' BCL2%0')  (' CASP9%0'  ' RAF_f%0')  (' CASP9%0'  ' mTORC1_c%0')  (' CASP9%0'  ' RHEB%0')  (' CASP9%0'  ' RTPK_g%0')  (' CASP9%0'  ' PTEN%0')  (' CASP9%0'  ' CASP3%0')  (' CASP9%0'  ' PIK3CA%0')  (' CASP9%0'  ' CREBBP%0')  (' CASP9%0'  ' PTPN11%0')  (' CASP9%0'  ' KRAS%0')  (' CASP9%0'  ' MAP2K4%0')  (' CASP9%0'  ' MAP2K7%0')  (' CASP9%0'  ' MAPK14%0')  (' CASP9%0'  ' JNK_f%0')  (' CASP9%0'  ' MAP2K3%0')  (' CASP9%0'  ' ERK_f%0')  (' CASP9%0'  ' LIF%0')  (' CASP9%0'  ' PPP1CA%0')  (' CASP9%0'  ' GAB_f%0')  (' CASP9%0'  ' SOS1%0')  (' CASP9%0'  ' PRKCA%0')  (' CASP9%0'  ' VAV1%0')  (' CASP9%0'  ' PLCG1%0')  (' CASP9%0'  ' PRKCD%0')  (' CASP9%0'  ' RSK_f%0')  (' CASP9%0'  ' S6K_f%0')  (' CASP9%0'  ' PLK1%0')  (' CASP9%0'  ' ILK%0')  (' CASP9%0'  ' SOCS1%0')  (' CASP9%0'  ' DUSP6%0')  (' CASP9%0'  ' STAT3%0')  (' CASP9%0'  ' LIMK2%0')  (' CASP9%0'  ' EP300%0')  (' CASP9%0'  ' STAT1%0')  (' CASP9%0'  ' IKBKB%0')  (' CASP9%0'  ' SRF%0')  (' CASP9%0'  ' PIAS1%0')  (' CASP9%0'  ' TRAF6%0')  (' CASP9%0'  ' SOCS1_g%0')  (' CASP9%0'  ' ISGF3_c%0')  (' CASP9%0'  ' STAT2%0')  (' CASP9%0'  ' CFLAR%0')  (' CASP9%0'  ' SMAD2%0')  (' CASP9%0'  ' MDM2_g%0')  (' CASP9%0'  ' BAX%0')  (' CASP9%0'  ' PRKACA%0')  (' CASP9%0'  ' TGFB1%0')  (' CASP9%0'  ' MAP3K8%0')  (' CASP9%0'  ' TSC_f%0')  (' CASP9%0'  ' SMAD4%0')  (' CASP9%0'  ' BAD%0')  (' CASP9%0'  ' MAP3K5%0')  (' CASP9%0'  ' AKT1S1%0')  (' CASP9%0'  ' SKI%0')  (' CASP9%0'  ' SMAD3%0')  (' CASP9%0'  ' MAPKAPK2%0')  (' CASP9%0'  ' DUSP1_g%0')  (' CASP9%0'  ' MSK_f%0')  (' CASP9%0'  ' GRAP2%0')  (' CASP9%0'  ' TAB_f%0')  (' CASP9%0'  ' ATF2%0')  (' CASP9%0'  ' SMAD5%0')  (' CASP9%0'  ' SMAD1%0')  (' CASP9%0'  ' FOS%0')  (' CASP9%0'  ' JUN%0')  (' CASP9%0'  ' MAP3K7%0')  (' CASP9%0'  ' NLK%0')  (' CASP9%0'  ' SMAD7_g%0')  (' CASP9%0'  ' SMAD6_g%0')  (' CASP9%0'  ' AP1_c%0')  (' CASP9%0'  ' ACVR1%0')  (' CASP9%0'  ' PTPN6%0')  (' CASP9%0'  ' CDC42%0')  (' CASP9%0'  ' GRB2%0')  (' CASP9%0'  ' TGFBR1%0')  (' CASP9%0'  ' SMURF1%0')  (' CASP9%0'  ' SMURF2%0')  (' CASP9%0'  ' RHOA%0')  (' CASP9%0'  ' BMPR2%0')  (' CASP9%0'  ' PARD6A%0')  (' CASP9%0'  ' DAAM1%0')  (' CASP9%0'  ' SFRP1_g%0')  (' CASP9%0'  ' PPM1A%0')  (' CASP9%0'  ' CFL_f%0')  (' CASP9%0'  ' PAK1%0')  (' CASP9%0'  ' MAP3K11%0')  (' CASP9%0'  ' MAP3K4%0')  (' CASP9%0'  ' LIMK1%0')  (' CASP9%0'  ' ROCK1%0')  (' CASP9%0'  ' ITCH%0')  (' CASP9%0'  ' ARHGAP24%0')  (' CASP9%0'  ' TIAM1%0')  (' CASP9%0'  ' RND3%0')  (' CASP9%0'  ' MAPK8IP3%0')  (' CASP9%0'  ' MXD1%0')  (' CASP9%0'  ' PIP3%0')  (' GSK3_f%0'  ' SRC%0')  (' GSK3_f%0'  ' CSK%0')  (' GSK3_f%0'  ' CHUK%0')  (' GSK3_f%0'  ' RAC_f%0')  (' GSK3_f%0'  ' DUSP1%0')  (' GSK3_f%0'  ' TGFBR2%0')  (' GSK3_f%0'  ' ILR_f%0')  (' GSK3_f%0'  ' SYK%0')  (' GSK3_f%0'  ' IRAK1%0')  (' GSK3_f%0'  ' SHC1%0')  (' GSK3_f%0'  ' JAK_f%0')  (' GSK3_f%0'  ' CBPp300_c%0')  (' GSK3_f%0'  ' SKP2%0')  (' GSK3_f%0'  ' TP53%0')  (' GSK3_f%0'  ' SMAD7%0')  (' GSK3_f%0'  ' SMAD6%0')  (' GSK3_f%0'  ' DKK_f%0')  (' GSK3_f%0'  ' FOXO_f%0')  (' GSK3_f%0'  ' TCF7_f%0')  (' GSK3_f%0'  ' DKK_g%0')  (' GSK3_f%0'  ' MYC%0')  (' GSK3_f%0'  ' CCND1%0')  (' GSK3_f%0'  ' EGR1%0')  (' GSK3_f%0'  ' MMP_f%0')  (' GSK3_f%0'  ' PTEN_g%0')  (' GSK3_f%0'  ' RTPK_f%0')  (' GSK3_f%0'  ' CTNNB1%0')  (' GSK3_f%0'  'LEF1%0')  (' GSK3_f%0'  'SFRP1%0')  (' GSK3_f%0'  'FZD_f%0')  (' GSK3_f%0'  ' CASP8%0')  (' GSK3_f%0'  ' REL_f%0')  (' GSK3_f%0'  ' NFKB_f%0')  (' GSK3_f%0'  ' DVL_f%0')  (' GSK3_f%0'  ' LRP_f%0')  (' GSK3_f%0'  ' BTRC%0')  (' GSK3_f%0'  ' CK1_f%0')  (' GSK3_f%0'  ' AXIN1%0')  (' GSK3_f%0'  ' mTORC2_c%0')  (' GSK3_f%0'  ' PDPK1%0')  (' GSK3_f%0'  ' MEK_f%0')  (' GSK3_f%0'  ' CYCS%0')  (' GSK3_f%0'  ' CASP9%0')  (' GSK3_f%0'  ' IRS1%0')  (' GSK3_f%0'  ' MDM2%0')  (' GSK3_f%0'  ' AKT_f%0')  (' GSK3_f%0'  ' BCL2%0')  (' GSK3_f%0'  ' RAF_f%0')  (' GSK3_f%0'  ' mTORC1_c%0')  (' GSK3_f%0'  ' RHEB%0')  (' GSK3_f%0'  ' RTPK_g%0')  (' GSK3_f%0'  ' PTEN%0')  (' GSK3_f%0'  ' CASP3%0')  (' GSK3_f%0'  ' PIK3CA%0')  (' GSK3_f%0'  ' CREBBP%0')  (' GSK3_f%0'  ' PTPN11%0')  (' GSK3_f%0'  ' KRAS%0')  (' GSK3_f%0'  ' MAP2K4%0')  (' GSK3_f%0'  ' MAP2K7%0')  (' GSK3_f%0'  ' MAPK14%0')  (' GSK3_f%0'  ' JNK_f%0')  (' GSK3_f%0'  ' MAP2K3%0')  (' GSK3_f%0'  ' ERK_f%0')  (' GSK3_f%0'  ' LIF%0')  (' GSK3_f%0'  ' PPP1CA%0')  (' GSK3_f%0'  ' GAB_f%0')  (' GSK3_f%0'  ' SOS1%0')  (' GSK3_f%0'  ' PRKCA%0')  (' GSK3_f%0'  ' VAV1%0')  (' GSK3_f%0'  ' PLCG1%0')  (' GSK3_f%0'  ' PRKCD%0')  (' GSK3_f%0'  ' RSK_f%0')  (' GSK3_f%0'  ' S6K_f%0')  (' GSK3_f%0'  ' PLK1%0')  (' GSK3_f%0'  ' ILK%0')  (' GSK3_f%0'  ' SOCS1%0')  (' GSK3_f%0'  ' DUSP6%0')  (' GSK3_f%0'  ' STAT3%0')  (' GSK3_f%0'  ' LIMK2%0')  (' GSK3_f%0'  ' EP300%0')  (' GSK3_f%0'  ' STAT1%0')  (' GSK3_f%0'  ' IKBKB%0')  (' GSK3_f%0'  ' SRF%0')  (' GSK3_f%0'  ' PIAS1%0')  (' GSK3_f%0'  ' TRAF6%0')  (' GSK3_f%0'  ' SOCS1_g%0')  (' GSK3_f%0'  ' ISGF3_c%0')  (' GSK3_f%0'  ' STAT2%0')  (' GSK3_f%0'  ' CFLAR%0')  (' GSK3_f%0'  ' SMAD2%0')  (' GSK3_f%0'  ' MDM2_g%0')  (' GSK3_f%0'  ' BAX%0')  (' GSK3_f%0'  ' PRKACA%0')  (' GSK3_f%0'  ' TGFB1%0')  (' GSK3_f%0'  ' MAP3K8%0')  (' GSK3_f%0'  ' TSC_f%0')  (' GSK3_f%0'  ' SMAD4%0')  (' GSK3_f%0'  ' BAD%0')  (' GSK3_f%0'  ' MAP3K5%0')  (' GSK3_f%0'  ' AKT1S1%0')  (' GSK3_f%0'  ' SKI%0')  (' GSK3_f%0'  ' SMAD3%0')  (' GSK3_f%0'  ' MAPKAPK2%0')  (' GSK3_f%0'  ' DUSP1_g%0')  (' GSK3_f%0'  ' MSK_f%0')  (' GSK3_f%0'  ' GRAP2%0')  (' GSK3_f%0'  ' TAB_f%0')  (' GSK3_f%0'  ' ATF2%0')  (' GSK3_f%0'  ' SMAD5%0')  (' GSK3_f%0'  ' SMAD1%0')  (' GSK3_f%0'  ' FOS%0')  (' GSK3_f%0'  ' JUN%0')  (' GSK3_f%0'  ' MAP3K7%0')  (' GSK3_f%0'  ' NLK%0')  (' GSK3_f%0'  ' SMAD7_g%0')  (' GSK3_f%0'  ' SMAD6_g%0')  (' GSK3_f%0'  ' AP1_c%0')  (' GSK3_f%0'  ' ACVR1%0')  (' GSK3_f%0'  ' PTPN6%0')  (' GSK3_f%0'  ' CDC42%0')  (' GSK3_f%0'  ' GRB2%0')  (' GSK3_f%0'  ' TGFBR1%0')  (' GSK3_f%0'  ' SMURF1%0')  (' GSK3_f%0'  ' SMURF2%0')  (' GSK3_f%0'  ' RHOA%0')  (' GSK3_f%0'  ' BMPR2%0')  (' GSK3_f%0'  ' PARD6A%0')  (' GSK3_f%0'  ' DAAM1%0')  (' GSK3_f%0'  ' SFRP1_g%0')  (' GSK3_f%0'  ' PPM1A%0')  (' GSK3_f%0'  ' CFL_f%0')  (' GSK3_f%0'  ' PAK1%0')  (' GSK3_f%0'  ' MAP3K11%0')  (' GSK3_f%0'  ' MAP3K4%0')  (' GSK3_f%0'  ' LIMK1%0')  (' GSK3_f%0'  ' ROCK1%0')  (' GSK3_f%0'  ' ITCH%0')  (' GSK3_f%0'  ' ARHGAP24%0')  (' GSK3_f%0'  ' TIAM1%0')  (' GSK3_f%0'  ' RND3%0')  (' GSK3_f%0'  ' MAPK8IP3%0')  (' GSK3_f%0'  ' MXD1%0')  (' GSK3_f%0'  ' PIP3%0')  (' IRS1%0'  ' SRC%0')  (' IRS1%0'  ' CSK%0')  (' IRS1%0'  ' CHUK%0')  (' IRS1%0'  ' RAC_f%0')  (' IRS1%0'  ' DUSP1%0')  (' IRS1%0'  ' TGFBR2%0')  (' IRS1%0'  ' ILR_f%0')  (' IRS1%0'  ' SYK%0')  (' IRS1%0'  ' IRAK1%0')  (' IRS1%0'  ' SHC1%0')  (' IRS1%0'  ' JAK_f%0')  (' IRS1%0'  ' CBPp300_c%0')  (' IRS1%0'  ' SKP2%0')  (' IRS1%0'  ' TP53%0')  (' IRS1%0'  ' SMAD7%0')  (' IRS1%0'  ' SMAD6%0')  (' IRS1%0'  ' DKK_f%0')  (' IRS1%0'  ' FOXO_f%0')  (' IRS1%0'  ' TCF7_f%0')  (' IRS1%0'  ' DKK_g%0')  (' IRS1%0'  ' MYC%0')  (' IRS1%0'  ' CCND1%0')  (' IRS1%0'  ' EGR1%0')  (' IRS1%0'  ' MMP_f%0')  (' IRS1%0'  ' PTEN_g%0')  (' IRS1%0'  ' RTPK_f%0')  (' IRS1%0'  ' CTNNB1%0')  (' IRS1%0'  'LEF1%0')  (' IRS1%0'  'SFRP1%0')  (' IRS1%0'  'FZD_f%0')  (' IRS1%0'  ' CASP8%0')  (' IRS1%0'  ' REL_f%0')  (' IRS1%0'  ' NFKB_f%0')  (' IRS1%0'  ' DVL_f%0')  (' IRS1%0'  ' LRP_f%0')  (' IRS1%0'  ' BTRC%0')  (' IRS1%0'  ' CK1_f%0')  (' IRS1%0'  ' AXIN1%0')  (' IRS1%0'  ' mTORC2_c%0')  (' IRS1%0'  ' PDPK1%0')  (' IRS1%0'  ' MEK_f%0')  (' IRS1%0'  ' CYCS%0')  (' IRS1%0'  ' CASP9%0')  (' IRS1%0'  ' GSK3_f%0')  (' IRS1%0'  ' MDM2%0')  (' IRS1%0'  ' AKT_f%0')  (' IRS1%0'  ' BCL2%0')  (' IRS1%0'  ' RAF_f%0')  (' IRS1%0'  ' mTORC1_c%0')  (' IRS1%0'  ' RHEB%0')  (' IRS1%0'  ' RTPK_g%0')  (' IRS1%0'  ' PTEN%0')  (' IRS1%0'  ' CASP3%0')  (' IRS1%0'  ' PIK3CA%0')  (' IRS1%0'  ' CREBBP%0')  (' IRS1%0'  ' PTPN11%0')  (' IRS1%0'  ' KRAS%0')  (' IRS1%0'  ' MAP2K4%0')  (' IRS1%0'  ' MAP2K7%0')  (' IRS1%0'  ' MAPK14%0')  (' IRS1%0'  ' JNK_f%0')  (' IRS1%0'  ' MAP2K3%0')  (' IRS1%0'  ' ERK_f%0')  (' IRS1%0'  ' LIF%0')  (' IRS1%0'  ' PPP1CA%0')  (' IRS1%0'  ' GAB_f%0')  (' IRS1%0'  ' SOS1%0')  (' IRS1%0'  ' PRKCA%0')  (' IRS1%0'  ' VAV1%0')  (' IRS1%0'  ' PLCG1%0')  (' IRS1%0'  ' PRKCD%0')  (' IRS1%0'  ' RSK_f%0')  (' IRS1%0'  ' S6K_f%0')  (' IRS1%0'  ' PLK1%0')  (' IRS1%0'  ' ILK%0')  (' IRS1%0'  ' SOCS1%0')  (' IRS1%0'  ' DUSP6%0')  (' IRS1%0'  ' STAT3%0')  (' IRS1%0'  ' LIMK2%0')  (' IRS1%0'  ' EP300%0')  (' IRS1%0'  ' STAT1%0')  (' IRS1%0'  ' IKBKB%0')  (' IRS1%0'  ' SRF%0')  (' IRS1%0'  ' PIAS1%0')  (' IRS1%0'  ' TRAF6%0')  (' IRS1%0'  ' SOCS1_g%0')  (' IRS1%0'  ' ISGF3_c%0')  (' IRS1%0'  ' STAT2%0')  (' IRS1%0'  ' CFLAR%0')  (' IRS1%0'  ' SMAD2%0')  (' IRS1%0'  ' MDM2_g%0')  (' IRS1%0'  ' BAX%0')  (' IRS1%0'  ' PRKACA%0')  (' IRS1%0'  ' TGFB1%0')  (' IRS1%0'  ' MAP3K8%0')  (' IRS1%0'  ' TSC_f%0')  (' IRS1%0'  ' SMAD4%0')  (' IRS1%0'  ' BAD%0')  (' IRS1%0'  ' MAP3K5%0')  (' IRS1%0'  ' AKT1S1%0')  (' IRS1%0'  ' SKI%0')  (' IRS1%0'  ' SMAD3%0')  (' IRS1%0'  ' MAPKAPK2%0')  (' IRS1%0'  ' DUSP1_g%0')  (' IRS1%0'  ' MSK_f%0')  (' IRS1%0'  ' GRAP2%0')  (' IRS1%0'  ' TAB_f%0')  (' IRS1%0'  ' ATF2%0')  (' IRS1%0'  ' SMAD5%0')  (' IRS1%0'  ' SMAD1%0')  (' IRS1%0'  ' FOS%0')  (' IRS1%0'  ' JUN%0')  (' IRS1%0'  ' MAP3K7%0')  (' IRS1%0'  ' NLK%0')  (' IRS1%0'  ' SMAD7_g%0')  (' IRS1%0'  ' SMAD6_g%0')  (' IRS1%0'  ' AP1_c%0')  (' IRS1%0'  ' ACVR1%0')  (' IRS1%0'  ' PTPN6%0')  (' IRS1%0'  ' CDC42%0')  (' IRS1%0'  ' GRB2%0')  (' IRS1%0'  ' TGFBR1%0')  (' IRS1%0'  ' SMURF1%0')  (' IRS1%0'  ' SMURF2%0')  (' IRS1%0'  ' RHOA%0')  (' IRS1%0'  ' BMPR2%0')  (' IRS1%0'  ' PARD6A%0')  (' IRS1%0'  ' DAAM1%0')  (' IRS1%0'  ' SFRP1_g%0')  (' IRS1%0'  ' PPM1A%0')  (' IRS1%0'  ' CFL_f%0')  (' IRS1%0'  ' PAK1%0')  (' IRS1%0'  ' MAP3K11%0')  (' IRS1%0'  ' MAP3K4%0')  (' IRS1%0'  ' LIMK1%0')  (' IRS1%0'  ' ROCK1%0')  (' IRS1%0'  ' ITCH%0')  (' IRS1%0'  ' ARHGAP24%0')  (' IRS1%0'  ' TIAM1%0')  (' IRS1%0'  ' RND3%0')  (' IRS1%0'  ' MAPK8IP3%0')  (' IRS1%0'  ' MXD1%0')  (' IRS1%0'  ' PIP3%0')  (' MDM2%0'  ' SRC%0')  (' MDM2%0'  ' CSK%0')  (' MDM2%0'  ' CHUK%0')  (' MDM2%0'  ' RAC_f%0')  (' MDM2%0'  ' DUSP1%0')  (' MDM2%0'  ' TGFBR2%0')  (' MDM2%0'  ' ILR_f%0')  (' MDM2%0'  ' SYK%0')  (' MDM2%0'  ' IRAK1%0')  (' MDM2%0'  ' SHC1%0')  (' MDM2%0'  ' JAK_f%0')  (' MDM2%0'  ' CBPp300_c%0')  (' MDM2%0'  ' SKP2%0')  (' MDM2%0'  ' TP53%0')  (' MDM2%0'  ' SMAD7%0')  (' MDM2%0'  ' SMAD6%0')  (' MDM2%0'  ' DKK_f%0')  (' MDM2%0'  ' FOXO_f%0')  (' MDM2%0'  ' TCF7_f%0')  (' MDM2%0'  ' DKK_g%0')  (' MDM2%0'  ' MYC%0')  (' MDM2%0'  ' CCND1%0')  (' MDM2%0'  ' EGR1%0')  (' MDM2%0'  ' MMP_f%0')  (' MDM2%0'  ' PTEN_g%0')  (' MDM2%0'  ' RTPK_f%0')  (' MDM2%0'  ' CTNNB1%0')  (' MDM2%0'  'LEF1%0')  (' MDM2%0'  'SFRP1%0')  (' MDM2%0'  'FZD_f%0')  (' MDM2%0'  ' CASP8%0')  (' MDM2%0'  ' REL_f%0')  (' MDM2%0'  ' NFKB_f%0')  (' MDM2%0'  ' DVL_f%0')  (' MDM2%0'  ' LRP_f%0')  (' MDM2%0'  ' BTRC%0')  (' MDM2%0'  ' CK1_f%0')  (' MDM2%0'  ' AXIN1%0')  (' MDM2%0'  ' mTORC2_c%0')  (' MDM2%0'  ' PDPK1%0')  (' MDM2%0'  ' MEK_f%0')  (' MDM2%0'  ' CYCS%0')  (' MDM2%0'  ' CASP9%0')  (' MDM2%0'  ' GSK3_f%0')  (' MDM2%0'  ' IRS1%0')  (' MDM2%0'  ' AKT_f%0')  (' MDM2%0'  ' BCL2%0')  (' MDM2%0'  ' RAF_f%0')  (' MDM2%0'  ' mTORC1_c%0')  (' MDM2%0'  ' RHEB%0')  (' MDM2%0'  ' RTPK_g%0')  (' MDM2%0'  ' PTEN%0')  (' MDM2%0'  ' CASP3%0')  (' MDM2%0'  ' PIK3CA%0')  (' MDM2%0'  ' CREBBP%0')  (' MDM2%0'  ' PTPN11%0')  (' MDM2%0'  ' KRAS%0')  (' MDM2%0'  ' MAP2K4%0')  (' MDM2%0'  ' MAP2K7%0')  (' MDM2%0'  ' MAPK14%0')  (' MDM2%0'  ' JNK_f%0')  (' MDM2%0'  ' MAP2K3%0')  (' MDM2%0'  ' ERK_f%0')  (' MDM2%0'  ' LIF%0')  (' MDM2%0'  ' PPP1CA%0')  (' MDM2%0'  ' GAB_f%0')  (' MDM2%0'  ' SOS1%0')  (' MDM2%0'  ' PRKCA%0')  (' MDM2%0'  ' VAV1%0')  (' MDM2%0'  ' PLCG1%0')  (' MDM2%0'  ' PRKCD%0')  (' MDM2%0'  ' RSK_f%0')  (' MDM2%0'  ' S6K_f%0')  (' MDM2%0'  ' PLK1%0')  (' MDM2%0'  ' ILK%0')  (' MDM2%0'  ' SOCS1%0')  (' MDM2%0'  ' DUSP6%0')  (' MDM2%0'  ' STAT3%0')  (' MDM2%0'  ' LIMK2%0')  (' MDM2%0'  ' EP300%0')  (' MDM2%0'  ' STAT1%0')  (' MDM2%0'  ' IKBKB%0')  (' MDM2%0'  ' SRF%0')  (' MDM2%0'  ' PIAS1%0')  (' MDM2%0'  ' TRAF6%0')  (' MDM2%0'  ' SOCS1_g%0')  (' MDM2%0'  ' ISGF3_c%0')  (' MDM2%0'  ' STAT2%0')  (' MDM2%0'  ' CFLAR%0')  (' MDM2%0'  ' SMAD2%0')  (' MDM2%0'  ' MDM2_g%0')  (' MDM2%0'  ' BAX%0')  (' MDM2%0'  ' PRKACA%0')  (' MDM2%0'  ' TGFB1%0')  (' MDM2%0'  ' MAP3K8%0')  (' MDM2%0'  ' TSC_f%0')  (' MDM2%0'  ' SMAD4%0')  (' MDM2%0'  ' BAD%0')  (' MDM2%0'  ' MAP3K5%0')  (' MDM2%0'  ' AKT1S1%0')  (' MDM2%0'  ' SKI%0')  (' MDM2%0'  ' SMAD3%0')  (' MDM2%0'  ' MAPKAPK2%0')  (' MDM2%0'  ' DUSP1_g%0')  (' MDM2%0'  ' MSK_f%0')  (' MDM2%0'  ' GRAP2%0')  (' MDM2%0'  ' TAB_f%0')  (' MDM2%0'  ' ATF2%0')  (' MDM2%0'  ' SMAD5%0')  (' MDM2%0'  ' SMAD1%0')  (' MDM2%0'  ' FOS%0')  (' MDM2%0'  ' JUN%0')  (' MDM2%0'  ' MAP3K7%0')  (' MDM2%0'  ' NLK%0')  (' MDM2%0'  ' SMAD7_g%0')  (' MDM2%0'  ' SMAD6_g%0')  (' MDM2%0'  ' AP1_c%0')  (' MDM2%0'  ' ACVR1%0')  (' MDM2%0'  ' PTPN6%0')  (' MDM2%0'  ' CDC42%0')  (' MDM2%0'  ' GRB2%0')  (' MDM2%0'  ' TGFBR1%0')  (' MDM2%0'  ' SMURF1%0')  (' MDM2%0'  ' SMURF2%0')  (' MDM2%0'  ' RHOA%0')  (' MDM2%0'  ' BMPR2%0')  (' MDM2%0'  ' PARD6A%0')  (' MDM2%0'  ' DAAM1%0')  (' MDM2%0'  ' SFRP1_g%0')  (' MDM2%0'  ' PPM1A%0')  (' MDM2%0'  ' CFL_f%0')  (' MDM2%0'  ' PAK1%0')  (' MDM2%0'  ' MAP3K11%0')  (' MDM2%0'  ' MAP3K4%0')  (' MDM2%0'  ' LIMK1%0')  (' MDM2%0'  ' ROCK1%0')  (' MDM2%0'  ' ITCH%0')  (' MDM2%0'  ' ARHGAP24%0')  (' MDM2%0'  ' TIAM1%0')  (' MDM2%0'  ' RND3%0')  (' MDM2%0'  ' MAPK8IP3%0')  (' MDM2%0'  ' MXD1%0')  (' MDM2%0'  ' PIP3%0')  (' AKT_f%0'  ' SRC%0')  (' AKT_f%0'  ' CSK%0')  (' AKT_f%0'  ' CHUK%0')  (' AKT_f%0'  ' RAC_f%0')  (' AKT_f%0'  ' DUSP1%0')  (' AKT_f%0'  ' TGFBR2%0')  (' AKT_f%0'  ' ILR_f%0')  (' AKT_f%0'  ' SYK%0')  (' AKT_f%0'  ' IRAK1%0')  (' AKT_f%0'  ' SHC1%0')  (' AKT_f%0'  ' JAK_f%0')  (' AKT_f%0'  ' CBPp300_c%0')  (' AKT_f%0'  ' SKP2%0')  (' AKT_f%0'  ' TP53%0')  (' AKT_f%0'  ' SMAD7%0')  (' AKT_f%0'  ' SMAD6%0')  (' AKT_f%0'  ' DKK_f%0')  (' AKT_f%0'  ' FOXO_f%0')  (' AKT_f%0'  ' TCF7_f%0')  (' AKT_f%0'  ' DKK_g%0')  (' AKT_f%0'  ' MYC%0')  (' AKT_f%0'  ' CCND1%0')  (' AKT_f%0'  ' EGR1%0')  (' AKT_f%0'  ' MMP_f%0')  (' AKT_f%0'  ' PTEN_g%0')  (' AKT_f%0'  ' RTPK_f%0')  (' AKT_f%0'  ' CTNNB1%0')  (' AKT_f%0'  'LEF1%0')  (' AKT_f%0'  'SFRP1%0')  (' AKT_f%0'  'FZD_f%0')  (' AKT_f%0'  ' CASP8%0')  (' AKT_f%0'  ' REL_f%0')  (' AKT_f%0'  ' NFKB_f%0')  (' AKT_f%0'  ' DVL_f%0')  (' AKT_f%0'  ' LRP_f%0')  (' AKT_f%0'  ' BTRC%0')  (' AKT_f%0'  ' CK1_f%0')  (' AKT_f%0'  ' AXIN1%0')  (' AKT_f%0'  ' mTORC2_c%0')  (' AKT_f%0'  ' PDPK1%0')  (' AKT_f%0'  ' MEK_f%0')  (' AKT_f%0'  ' CYCS%0')  (' AKT_f%0'  ' CASP9%0')  (' AKT_f%0'  ' GSK3_f%0')  (' AKT_f%0'  ' IRS1%0')  (' AKT_f%0'  ' MDM2%0')  (' AKT_f%0'  ' BCL2%0')  (' AKT_f%0'  ' RAF_f%0')  (' AKT_f%0'  ' mTORC1_c%0')  (' AKT_f%0'  ' RHEB%0')  (' AKT_f%0'  ' RTPK_g%0')  (' AKT_f%0'  ' PTEN%0')  (' AKT_f%0'  ' CASP3%0')  (' AKT_f%0'  ' PIK3CA%0')  (' AKT_f%0'  ' CREBBP%0')  (' AKT_f%0'  ' PTPN11%0')  (' AKT_f%0'  ' KRAS%0')  (' AKT_f%0'  ' MAP2K4%0')  (' AKT_f%0'  ' MAP2K7%0')  (' AKT_f%0'  ' MAPK14%0')  (' AKT_f%0'  ' JNK_f%0')  (' AKT_f%0'  ' MAP2K3%0')  (' AKT_f%0'  ' ERK_f%0')  (' AKT_f%0'  ' LIF%0')  (' AKT_f%0'  ' PPP1CA%0')  (' AKT_f%0'  ' GAB_f%0')  (' AKT_f%0'  ' SOS1%0')  (' AKT_f%0'  ' PRKCA%0')  (' AKT_f%0'  ' VAV1%0')  (' AKT_f%0'  ' PLCG1%0')  (' AKT_f%0'  ' PRKCD%0')  (' AKT_f%0'  ' RSK_f%0')  (' AKT_f%0'  ' S6K_f%0')  (' AKT_f%0'  ' PLK1%0')  (' AKT_f%0'  ' ILK%0')  (' AKT_f%0'  ' SOCS1%0')  (' AKT_f%0'  ' DUSP6%0')  (' AKT_f%0'  ' STAT3%0')  (' AKT_f%0'  ' LIMK2%0')  (' AKT_f%0'  ' EP300%0')  (' AKT_f%0'  ' STAT1%0')  (' AKT_f%0'  ' IKBKB%0')  (' AKT_f%0'  ' SRF%0')  (' AKT_f%0'  ' PIAS1%0')  (' AKT_f%0'  ' TRAF6%0')  (' AKT_f%0'  ' SOCS1_g%0')  (' AKT_f%0'  ' ISGF3_c%0')  (' AKT_f%0'  ' STAT2%0')  (' AKT_f%0'  ' CFLAR%0')  (' AKT_f%0'  ' SMAD2%0')  (' AKT_f%0'  ' MDM2_g%0')  (' AKT_f%0'  ' BAX%0')  (' AKT_f%0'  ' PRKACA%0')  (' AKT_f%0'  ' TGFB1%0')  (' AKT_f%0'  ' MAP3K8%0')  (' AKT_f%0'  ' TSC_f%0')  (' AKT_f%0'  ' SMAD4%0')  (' AKT_f%0'  ' BAD%0')  (' AKT_f%0'  ' MAP3K5%0')  (' AKT_f%0'  ' AKT1S1%0')  (' AKT_f%0'  ' SKI%0')  (' AKT_f%0'  ' SMAD3%0')  (' AKT_f%0'  ' MAPKAPK2%0')  (' AKT_f%0'  ' DUSP1_g%0')  (' AKT_f%0'  ' MSK_f%0')  (' AKT_f%0'  ' GRAP2%0')  (' AKT_f%0'  ' TAB_f%0')  (' AKT_f%0'  ' ATF2%0')  (' AKT_f%0'  ' SMAD5%0')  (' AKT_f%0'  ' SMAD1%0')  (' AKT_f%0'  ' FOS%0')  (' AKT_f%0'  ' JUN%0')  (' AKT_f%0'  ' MAP3K7%0')  (' AKT_f%0'  ' NLK%0')  (' AKT_f%0'  ' SMAD7_g%0')  (' AKT_f%0'  ' SMAD6_g%0')  (' AKT_f%0'  ' AP1_c%0')  (' AKT_f%0'  ' ACVR1%0')  (' AKT_f%0'  ' PTPN6%0')  (' AKT_f%0'  ' CDC42%0')  (' AKT_f%0'  ' GRB2%0')  (' AKT_f%0'  ' TGFBR1%0')  (' AKT_f%0'  ' SMURF1%0')  (' AKT_f%0'  ' SMURF2%0')  (' AKT_f%0'  ' RHOA%0')  (' AKT_f%0'  ' BMPR2%0')  (' AKT_f%0'  ' PARD6A%0')  (' AKT_f%0'  ' DAAM1%0')  (' AKT_f%0'  ' SFRP1_g%0')  (' AKT_f%0'  ' PPM1A%0')  (' AKT_f%0'  ' CFL_f%0')  (' AKT_f%0'  ' PAK1%0')  (' AKT_f%0'  ' MAP3K11%0')  (' AKT_f%0'  ' MAP3K4%0')  (' AKT_f%0'  ' LIMK1%0')  (' AKT_f%0'  ' ROCK1%0')  (' AKT_f%0'  ' ITCH%0')  (' AKT_f%0'  ' ARHGAP24%0')  (' AKT_f%0'  ' TIAM1%0')  (' AKT_f%0'  ' RND3%0')  (' AKT_f%0'  ' MAPK8IP3%0')  (' AKT_f%0'  ' MXD1%0')  (' AKT_f%0'  ' PIP3%0')  (' BCL2%0'  ' SRC%0')  (' BCL2%0'  ' CSK%0')  (' BCL2%0'  ' CHUK%0')  (' BCL2%0'  ' RAC_f%0')  (' BCL2%0'  ' DUSP1%0')  (' BCL2%0'  ' TGFBR2%0')  (' BCL2%0'  ' ILR_f%0')  (' BCL2%0'  ' SYK%0')  (' BCL2%0'  ' IRAK1%0')  (' BCL2%0'  ' SHC1%0')  (' BCL2%0'  ' JAK_f%0')  (' BCL2%0'  ' CBPp300_c%0')  (' BCL2%0'  ' SKP2%0')  (' BCL2%0'  ' TP53%0')  (' BCL2%0'  ' SMAD7%0')  (' BCL2%0'  ' SMAD6%0')  (' BCL2%0'  ' DKK_f%0')  (' BCL2%0'  ' FOXO_f%0')  (' BCL2%0'  ' TCF7_f%0')  (' BCL2%0'  ' DKK_g%0')  (' BCL2%0'  ' MYC%0')  (' BCL2%0'  ' CCND1%0')  (' BCL2%0'  ' EGR1%0')  (' BCL2%0'  ' MMP_f%0')  (' BCL2%0'  ' PTEN_g%0')  (' BCL2%0'  ' RTPK_f%0')  (' BCL2%0'  ' CTNNB1%0')  (' BCL2%0'  'LEF1%0')  (' BCL2%0'  'SFRP1%0')  (' BCL2%0'  'FZD_f%0')  (' BCL2%0'  ' CASP8%0')  (' BCL2%0'  ' REL_f%0')  (' BCL2%0'  ' NFKB_f%0')  (' BCL2%0'  ' DVL_f%0')  (' BCL2%0'  ' LRP_f%0')  (' BCL2%0'  ' BTRC%0')  (' BCL2%0'  ' CK1_f%0')  (' BCL2%0'  ' AXIN1%0')  (' BCL2%0'  ' mTORC2_c%0')  (' BCL2%0'  ' PDPK1%0')  (' BCL2%0'  ' MEK_f%0')  (' BCL2%0'  ' CYCS%0')  (' BCL2%0'  ' CASP9%0')  (' BCL2%0'  ' GSK3_f%0')  (' BCL2%0'  ' IRS1%0')  (' BCL2%0'  ' MDM2%0')  (' BCL2%0'  ' AKT_f%0')  (' BCL2%0'  ' RAF_f%0')  (' BCL2%0'  ' mTORC1_c%0')  (' BCL2%0'  ' RHEB%0')  (' BCL2%0'  ' RTPK_g%0')  (' BCL2%0'  ' PTEN%0')  (' BCL2%0'  ' CASP3%0')  (' BCL2%0'  ' PIK3CA%0')  (' BCL2%0'  ' CREBBP%0')  (' BCL2%0'  ' PTPN11%0')  (' BCL2%0'  ' KRAS%0')  (' BCL2%0'  ' MAP2K4%0')  (' BCL2%0'  ' MAP2K7%0')  (' BCL2%0'  ' MAPK14%0')  (' BCL2%0'  ' JNK_f%0')  (' BCL2%0'  ' MAP2K3%0')  (' BCL2%0'  ' ERK_f%0')  (' BCL2%0'  ' LIF%0')  (' BCL2%0'  ' PPP1CA%0')  (' BCL2%0'  ' GAB_f%0')  (' BCL2%0'  ' SOS1%0')  (' BCL2%0'  ' PRKCA%0')  (' BCL2%0'  ' VAV1%0')  (' BCL2%0'  ' PLCG1%0')  (' BCL2%0'  ' PRKCD%0')  (' BCL2%0'  ' RSK_f%0')  (' BCL2%0'  ' S6K_f%0')  (' BCL2%0'  ' PLK1%0')  (' BCL2%0'  ' ILK%0')  (' BCL2%0'  ' SOCS1%0')  (' BCL2%0'  ' DUSP6%0')  (' BCL2%0'  ' STAT3%0')  (' BCL2%0'  ' LIMK2%0')  (' BCL2%0'  ' EP300%0')  (' BCL2%0'  ' STAT1%0')  (' BCL2%0'  ' IKBKB%0')  (' BCL2%0'  ' SRF%0')  (' BCL2%0'  ' PIAS1%0')  (' BCL2%0'  ' TRAF6%0')  (' BCL2%0'  ' SOCS1_g%0')  (' BCL2%0'  ' ISGF3_c%0')  (' BCL2%0'  ' STAT2%0')  (' BCL2%0'  ' CFLAR%0')  (' BCL2%0'  ' SMAD2%0')  (' BCL2%0'  ' MDM2_g%0')  (' BCL2%0'  ' BAX%0')  (' BCL2%0'  ' PRKACA%0')  (' BCL2%0'  ' TGFB1%0')  (' BCL2%0'  ' MAP3K8%0')  (' BCL2%0'  ' TSC_f%0')  (' BCL2%0'  ' SMAD4%0')  (' BCL2%0'  ' BAD%0')  (' BCL2%0'  ' MAP3K5%0')  (' BCL2%0'  ' AKT1S1%0')  (' BCL2%0'  ' SKI%0')  (' BCL2%0'  ' SMAD3%0')  (' BCL2%0'  ' MAPKAPK2%0')  (' BCL2%0'  ' DUSP1_g%0')  (' BCL2%0'  ' MSK_f%0')  (' BCL2%0'  ' GRAP2%0')  (' BCL2%0'  ' TAB_f%0')  (' BCL2%0'  ' ATF2%0')  (' BCL2%0'  ' SMAD5%0')  (' BCL2%0'  ' SMAD1%0')  (' BCL2%0'  ' FOS%0')  (' BCL2%0'  ' JUN%0')  (' BCL2%0'  ' MAP3K7%0')  (' BCL2%0'  ' NLK%0')  (' BCL2%0'  ' SMAD7_g%0')  (' BCL2%0'  ' SMAD6_g%0')  (' BCL2%0'  ' AP1_c%0')  (' BCL2%0'  ' ACVR1%0')  (' BCL2%0'  ' PTPN6%0')  (' BCL2%0'  ' CDC42%0')  (' BCL2%0'  ' GRB2%0')  (' BCL2%0'  ' TGFBR1%0')  (' BCL2%0'  ' SMURF1%0')  (' BCL2%0'  ' SMURF2%0')  (' BCL2%0'  ' RHOA%0')  (' BCL2%0'  ' BMPR2%0')  (' BCL2%0'  ' PARD6A%0')  (' BCL2%0'  ' DAAM1%0')  (' BCL2%0'  ' SFRP1_g%0')  (' BCL2%0'  ' PPM1A%0')  (' BCL2%0'  ' CFL_f%0')  (' BCL2%0'  ' PAK1%0')  (' BCL2%0'  ' MAP3K11%0')  (' BCL2%0'  ' MAP3K4%0')  (' BCL2%0'  ' LIMK1%0')  (' BCL2%0'  ' ROCK1%0')  (' BCL2%0'  ' ITCH%0')  (' BCL2%0'  ' ARHGAP24%0')  (' BCL2%0'  ' TIAM1%0')  (' BCL2%0'  ' RND3%0')  (' BCL2%0'  ' MAPK8IP3%0')  (' BCL2%0'  ' MXD1%0')  (' BCL2%0'  ' PIP3%0')  (' RAF_f%0'  ' SRC%0')  (' RAF_f%0'  ' CSK%0')  (' RAF_f%0'  ' CHUK%0')  (' RAF_f%0'  ' RAC_f%0')  (' RAF_f%0'  ' DUSP1%0')  (' RAF_f%0'  ' TGFBR2%0')  (' RAF_f%0'  ' ILR_f%0')  (' RAF_f%0'  ' SYK%0')  (' RAF_f%0'  ' IRAK1%0')  (' RAF_f%0'  ' SHC1%0')  (' RAF_f%0'  ' JAK_f%0')  (' RAF_f%0'  ' CBPp300_c%0')  (' RAF_f%0'  ' SKP2%0')  (' RAF_f%0'  ' TP53%0')  (' RAF_f%0'  ' SMAD7%0')  (' RAF_f%0'  ' SMAD6%0')  (' RAF_f%0'  ' DKK_f%0')  (' RAF_f%0'  ' FOXO_f%0')  (' RAF_f%0'  ' TCF7_f%0')  (' RAF_f%0'  ' DKK_g%0')  (' RAF_f%0'  ' MYC%0')  (' RAF_f%0'  ' CCND1%0')  (' RAF_f%0'  ' EGR1%0')  (' RAF_f%0'  ' MMP_f%0')  (' RAF_f%0'  ' PTEN_g%0')  (' RAF_f%0'  ' RTPK_f%0')  (' RAF_f%0'  ' CTNNB1%0')  (' RAF_f%0'  'LEF1%0')  (' RAF_f%0'  'SFRP1%0')  (' RAF_f%0'  'FZD_f%0')  (' RAF_f%0'  ' CASP8%0')  (' RAF_f%0'  ' REL_f%0')  (' RAF_f%0'  ' NFKB_f%0')  (' RAF_f%0'  ' DVL_f%0')  (' RAF_f%0'  ' LRP_f%0')  (' RAF_f%0'  ' BTRC%0')  (' RAF_f%0'  ' CK1_f%0')  (' RAF_f%0'  ' AXIN1%0')  (' RAF_f%0'  ' mTORC2_c%0')  (' RAF_f%0'  ' PDPK1%0')  (' RAF_f%0'  ' MEK_f%0')  (' RAF_f%0'  ' CYCS%0')  (' RAF_f%0'  ' CASP9%0')  (' RAF_f%0'  ' GSK3_f%0')  (' RAF_f%0'  ' IRS1%0')  (' RAF_f%0'  ' MDM2%0')  (' RAF_f%0'  ' AKT_f%0')  (' RAF_f%0'  ' BCL2%0')  (' RAF_f%0'  ' mTORC1_c%0')  (' RAF_f%0'  ' RHEB%0')  (' RAF_f%0'  ' RTPK_g%0')  (' RAF_f%0'  ' PTEN%0')  (' RAF_f%0'  ' CASP3%0')  (' RAF_f%0'  ' PIK3CA%0')  (' RAF_f%0'  ' CREBBP%0')  (' RAF_f%0'  ' PTPN11%0')  (' RAF_f%0'  ' KRAS%0')  (' RAF_f%0'  ' MAP2K4%0')  (' RAF_f%0'  ' MAP2K7%0')  (' RAF_f%0'  ' MAPK14%0')  (' RAF_f%0'  ' JNK_f%0')  (' RAF_f%0'  ' MAP2K3%0')  (' RAF_f%0'  ' ERK_f%0')  (' RAF_f%0'  ' LIF%0')  (' RAF_f%0'  ' PPP1CA%0')  (' RAF_f%0'  ' GAB_f%0')  (' RAF_f%0'  ' SOS1%0')  (' RAF_f%0'  ' PRKCA%0')  (' RAF_f%0'  ' VAV1%0')  (' RAF_f%0'  ' PLCG1%0')  (' RAF_f%0'  ' PRKCD%0')  (' RAF_f%0'  ' RSK_f%0')  (' RAF_f%0'  ' S6K_f%0')  (' RAF_f%0'  ' PLK1%0')  (' RAF_f%0'  ' ILK%0')  (' RAF_f%0'  ' SOCS1%0')  (' RAF_f%0'  ' DUSP6%0')  (' RAF_f%0'  ' STAT3%0')  (' RAF_f%0'  ' LIMK2%0')  (' RAF_f%0'  ' EP300%0')  (' RAF_f%0'  ' STAT1%0')  (' RAF_f%0'  ' IKBKB%0')  (' RAF_f%0'  ' SRF%0')  (' RAF_f%0'  ' PIAS1%0')  (' RAF_f%0'  ' TRAF6%0')  (' RAF_f%0'  ' SOCS1_g%0')  (' RAF_f%0'  ' ISGF3_c%0')  (' RAF_f%0'  ' STAT2%0')  (' RAF_f%0'  ' CFLAR%0')  (' RAF_f%0'  ' SMAD2%0')  (' RAF_f%0'  ' MDM2_g%0')  (' RAF_f%0'  ' BAX%0')  (' RAF_f%0'  ' PRKACA%0')  (' RAF_f%0'  ' TGFB1%0')  (' RAF_f%0'  ' MAP3K8%0')  (' RAF_f%0'  ' TSC_f%0')  (' RAF_f%0'  ' SMAD4%0')  (' RAF_f%0'  ' BAD%0')  (' RAF_f%0'  ' MAP3K5%0')  (' RAF_f%0'  ' AKT1S1%0')  (' RAF_f%0'  ' SKI%0')  (' RAF_f%0'  ' SMAD3%0')  (' RAF_f%0'  ' MAPKAPK2%0')  (' RAF_f%0'  ' DUSP1_g%0')  (' RAF_f%0'  ' MSK_f%0')  (' RAF_f%0'  ' GRAP2%0')  (' RAF_f%0'  ' TAB_f%0')  (' RAF_f%0'  ' ATF2%0')  (' RAF_f%0'  ' SMAD5%0')  (' RAF_f%0'  ' SMAD1%0')  (' RAF_f%0'  ' FOS%0')  (' RAF_f%0'  ' JUN%0')  (' RAF_f%0'  ' MAP3K7%0')  (' RAF_f%0'  ' NLK%0')  (' RAF_f%0'  ' SMAD7_g%0')  (' RAF_f%0'  ' SMAD6_g%0')  (' RAF_f%0'  ' AP1_c%0')  (' RAF_f%0'  ' ACVR1%0')  (' RAF_f%0'  ' PTPN6%0')  (' RAF_f%0'  ' CDC42%0')  (' RAF_f%0'  ' GRB2%0')  (' RAF_f%0'  ' TGFBR1%0')  (' RAF_f%0'  ' SMURF1%0')  (' RAF_f%0'  ' SMURF2%0')  (' RAF_f%0'  ' RHOA%0')  (' RAF_f%0'  ' BMPR2%0')  (' RAF_f%0'  ' PARD6A%0')  (' RAF_f%0'  ' DAAM1%0')  (' RAF_f%0'  ' SFRP1_g%0')  (' RAF_f%0'  ' PPM1A%0')  (' RAF_f%0'  ' CFL_f%0')  (' RAF_f%0'  ' PAK1%0')  (' RAF_f%0'  ' MAP3K11%0')  (' RAF_f%0'  ' MAP3K4%0')  (' RAF_f%0'  ' LIMK1%0')  (' RAF_f%0'  ' ROCK1%0')  (' RAF_f%0'  ' ITCH%0')  (' RAF_f%0'  ' ARHGAP24%0')  (' RAF_f%0'  ' TIAM1%0')  (' RAF_f%0'  ' RND3%0')  (' RAF_f%0'  ' MAPK8IP3%0')  (' RAF_f%0'  ' MXD1%0')  (' RAF_f%0'  ' PIP3%0')  (' mTORC1_c%0'  ' SRC%0')  (' mTORC1_c%0'  ' CSK%0')  (' mTORC1_c%0'  ' CHUK%0')  (' mTORC1_c%0'  ' RAC_f%0')  (' mTORC1_c%0'  ' DUSP1%0')  (' mTORC1_c%0'  ' TGFBR2%0')  (' mTORC1_c%0'  ' ILR_f%0')  (' mTORC1_c%0'  ' SYK%0')  (' mTORC1_c%0'  ' IRAK1%0')  (' mTORC1_c%0'  ' SHC1%0')  (' mTORC1_c%0'  ' JAK_f%0')  (' mTORC1_c%0'  ' CBPp300_c%0')  (' mTORC1_c%0'  ' SKP2%0')  (' mTORC1_c%0'  ' TP53%0')  (' mTORC1_c%0'  ' SMAD7%0')  (' mTORC1_c%0'  ' SMAD6%0')  (' mTORC1_c%0'  ' DKK_f%0')  (' mTORC1_c%0'  ' FOXO_f%0')  (' mTORC1_c%0'  ' TCF7_f%0')  (' mTORC1_c%0'  ' DKK_g%0')  (' mTORC1_c%0'  ' MYC%0')  (' mTORC1_c%0'  ' CCND1%0')  (' mTORC1_c%0'  ' EGR1%0')  (' mTORC1_c%0'  ' MMP_f%0')  (' mTORC1_c%0'  ' PTEN_g%0')  (' mTORC1_c%0'  ' RTPK_f%0')  (' mTORC1_c%0'  ' CTNNB1%0')  (' mTORC1_c%0'  'LEF1%0')  (' mTORC1_c%0'  'SFRP1%0')  (' mTORC1_c%0'  'FZD_f%0')  (' mTORC1_c%0'  ' CASP8%0')  (' mTORC1_c%0'  ' REL_f%0')  (' mTORC1_c%0'  ' NFKB_f%0')  (' mTORC1_c%0'  ' DVL_f%0')  (' mTORC1_c%0'  ' LRP_f%0')  (' mTORC1_c%0'  ' BTRC%0')  (' mTORC1_c%0'  ' CK1_f%0')  (' mTORC1_c%0'  ' AXIN1%0')  (' mTORC1_c%0'  ' mTORC2_c%0')  (' mTORC1_c%0'  ' PDPK1%0')  (' mTORC1_c%0'  ' MEK_f%0')  (' mTORC1_c%0'  ' CYCS%0')  (' mTORC1_c%0'  ' CASP9%0')  (' mTORC1_c%0'  ' GSK3_f%0')  (' mTORC1_c%0'  ' IRS1%0')  (' mTORC1_c%0'  ' MDM2%0')  (' mTORC1_c%0'  ' AKT_f%0')  (' mTORC1_c%0'  ' BCL2%0')  (' mTORC1_c%0'  ' RAF_f%0')  (' mTORC1_c%0'  ' RHEB%0')  (' mTORC1_c%0'  ' RTPK_g%0')  (' mTORC1_c%0'  ' PTEN%0')  (' mTORC1_c%0'  ' CASP3%0')  (' mTORC1_c%0'  ' PIK3CA%0')  (' mTORC1_c%0'  ' CREBBP%0')  (' mTORC1_c%0'  ' PTPN11%0')  (' mTORC1_c%0'  ' KRAS%0')  (' mTORC1_c%0'  ' MAP2K4%0')  (' mTORC1_c%0'  ' MAP2K7%0')  (' mTORC1_c%0'  ' MAPK14%0')  (' mTORC1_c%0'  ' JNK_f%0')  (' mTORC1_c%0'  ' MAP2K3%0')  (' mTORC1_c%0'  ' ERK_f%0')  (' mTORC1_c%0'  ' LIF%0')  (' mTORC1_c%0'  ' PPP1CA%0')  (' mTORC1_c%0'  ' GAB_f%0')  (' mTORC1_c%0'  ' SOS1%0')  (' mTORC1_c%0'  ' PRKCA%0')  (' mTORC1_c%0'  ' VAV1%0')  (' mTORC1_c%0'  ' PLCG1%0')  (' mTORC1_c%0'  ' PRKCD%0')  (' mTORC1_c%0'  ' RSK_f%0')  (' mTORC1_c%0'  ' S6K_f%0')  (' mTORC1_c%0'  ' PLK1%0')  (' mTORC1_c%0'  ' ILK%0')  (' mTORC1_c%0'  ' SOCS1%0')  (' mTORC1_c%0'  ' DUSP6%0')  (' mTORC1_c%0'  ' STAT3%0')  (' mTORC1_c%0'  ' LIMK2%0')  (' mTORC1_c%0'  ' EP300%0')  (' mTORC1_c%0'  ' STAT1%0')  (' mTORC1_c%0'  ' IKBKB%0')  (' mTORC1_c%0'  ' SRF%0')  (' mTORC1_c%0'  ' PIAS1%0')  (' mTORC1_c%0'  ' TRAF6%0')  (' mTORC1_c%0'  ' SOCS1_g%0')  (' mTORC1_c%0'  ' ISGF3_c%0')  (' mTORC1_c%0'  ' STAT2%0')  (' mTORC1_c%0'  ' CFLAR%0')  (' mTORC1_c%0'  ' SMAD2%0')  (' mTORC1_c%0'  ' MDM2_g%0')  (' mTORC1_c%0'  ' BAX%0')  (' mTORC1_c%0'  ' PRKACA%0')  (' mTORC1_c%0'  ' TGFB1%0')  (' mTORC1_c%0'  ' MAP3K8%0')  (' mTORC1_c%0'  ' TSC_f%0')  (' mTORC1_c%0'  ' SMAD4%0')  (' mTORC1_c%0'  ' BAD%0')  (' mTORC1_c%0'  ' MAP3K5%0')  (' mTORC1_c%0'  ' AKT1S1%0')  (' mTORC1_c%0'  ' SKI%0')  (' mTORC1_c%0'  ' SMAD3%0')  (' mTORC1_c%0'  ' MAPKAPK2%0')  (' mTORC1_c%0'  ' DUSP1_g%0')  (' mTORC1_c%0'  ' MSK_f%0')  (' mTORC1_c%0'  ' GRAP2%0')  (' mTORC1_c%0'  ' TAB_f%0')  (' mTORC1_c%0'  ' ATF2%0')  (' mTORC1_c%0'  ' SMAD5%0')  (' mTORC1_c%0'  ' SMAD1%0')  (' mTORC1_c%0'  ' FOS%0')  (' mTORC1_c%0'  ' JUN%0')  (' mTORC1_c%0'  ' MAP3K7%0')  (' mTORC1_c%0'  ' NLK%0')  (' mTORC1_c%0'  ' SMAD7_g%0')  (' mTORC1_c%0'  ' SMAD6_g%0')  (' mTORC1_c%0'  ' AP1_c%0')  (' mTORC1_c%0'  ' ACVR1%0')  (' mTORC1_c%0'  ' PTPN6%0')  (' mTORC1_c%0'  ' CDC42%0')  (' mTORC1_c%0'  ' GRB2%0')  (' mTORC1_c%0'  ' TGFBR1%0')  (' mTORC1_c%0'  ' SMURF1%0')  (' mTORC1_c%0'  ' SMURF2%0')  (' mTORC1_c%0'  ' RHOA%0')  (' mTORC1_c%0'  ' BMPR2%0')  (' mTORC1_c%0'  ' PARD6A%0')  (' mTORC1_c%0'  ' DAAM1%0')  (' mTORC1_c%0'  ' SFRP1_g%0')  (' mTORC1_c%0'  ' PPM1A%0')  (' mTORC1_c%0'  ' CFL_f%0')  (' mTORC1_c%0'  ' PAK1%0')  (' mTORC1_c%0'  ' MAP3K11%0')  (' mTORC1_c%0'  ' MAP3K4%0')  (' mTORC1_c%0'  ' LIMK1%0')  (' mTORC1_c%0'  ' ROCK1%0')  (' mTORC1_c%0'  ' ITCH%0')  (' mTORC1_c%0'  ' ARHGAP24%0')  (' mTORC1_c%0'  ' TIAM1%0')  (' mTORC1_c%0'  ' RND3%0')  (' mTORC1_c%0'  ' MAPK8IP3%0')  (' mTORC1_c%0'  ' MXD1%0')  (' mTORC1_c%0'  ' PIP3%0')  (' RHEB%0'  ' SRC%0')  (' RHEB%0'  ' CSK%0')  (' RHEB%0'  ' CHUK%0')  (' RHEB%0'  ' RAC_f%0')  (' RHEB%0'  ' DUSP1%0')  (' RHEB%0'  ' TGFBR2%0')  (' RHEB%0'  ' ILR_f%0')  (' RHEB%0'  ' SYK%0')  (' RHEB%0'  ' IRAK1%0')  (' RHEB%0'  ' SHC1%0')  (' RHEB%0'  ' JAK_f%0')  (' RHEB%0'  ' CBPp300_c%0')  (' RHEB%0'  ' SKP2%0')  (' RHEB%0'  ' TP53%0')  (' RHEB%0'  ' SMAD7%0')  (' RHEB%0'  ' SMAD6%0')  (' RHEB%0'  ' DKK_f%0')  (' RHEB%0'  ' FOXO_f%0')  (' RHEB%0'  ' TCF7_f%0')  (' RHEB%0'  ' DKK_g%0')  (' RHEB%0'  ' MYC%0')  (' RHEB%0'  ' CCND1%0')  (' RHEB%0'  ' EGR1%0')  (' RHEB%0'  ' MMP_f%0')  (' RHEB%0'  ' PTEN_g%0')  (' RHEB%0'  ' RTPK_f%0')  (' RHEB%0'  ' CTNNB1%0')  (' RHEB%0'  'LEF1%0')  (' RHEB%0'  'SFRP1%0')  (' RHEB%0'  'FZD_f%0')  (' RHEB%0'  ' CASP8%0')  (' RHEB%0'  ' REL_f%0')  (' RHEB%0'  ' NFKB_f%0')  (' RHEB%0'  ' DVL_f%0')  (' RHEB%0'  ' LRP_f%0')  (' RHEB%0'  ' BTRC%0')  (' RHEB%0'  ' CK1_f%0')  (' RHEB%0'  ' AXIN1%0')  (' RHEB%0'  ' mTORC2_c%0')  (' RHEB%0'  ' PDPK1%0')  (' RHEB%0'  ' MEK_f%0')  (' RHEB%0'  ' CYCS%0')  (' RHEB%0'  ' CASP9%0')  (' RHEB%0'  ' GSK3_f%0')  (' RHEB%0'  ' IRS1%0')  (' RHEB%0'  ' MDM2%0')  (' RHEB%0'  ' AKT_f%0')  (' RHEB%0'  ' BCL2%0')  (' RHEB%0'  ' RAF_f%0')  (' RHEB%0'  ' mTORC1_c%0')  (' RHEB%0'  ' RTPK_g%0')  (' RHEB%0'  ' PTEN%0')  (' RHEB%0'  ' CASP3%0')  (' RHEB%0'  ' PIK3CA%0')  (' RHEB%0'  ' CREBBP%0')  (' RHEB%0'  ' PTPN11%0')  (' RHEB%0'  ' KRAS%0')  (' RHEB%0'  ' MAP2K4%0')  (' RHEB%0'  ' MAP2K7%0')  (' RHEB%0'  ' MAPK14%0')  (' RHEB%0'  ' JNK_f%0')  (' RHEB%0'  ' MAP2K3%0')  (' RHEB%0'  ' ERK_f%0')  (' RHEB%0'  ' LIF%0')  (' RHEB%0'  ' PPP1CA%0')  (' RHEB%0'  ' GAB_f%0')  (' RHEB%0'  ' SOS1%0')  (' RHEB%0'  ' PRKCA%0')  (' RHEB%0'  ' VAV1%0')  (' RHEB%0'  ' PLCG1%0')  (' RHEB%0'  ' PRKCD%0')  (' RHEB%0'  ' RSK_f%0')  (' RHEB%0'  ' S6K_f%0')  (' RHEB%0'  ' PLK1%0')  (' RHEB%0'  ' ILK%0')  (' RHEB%0'  ' SOCS1%0')  (' RHEB%0'  ' DUSP6%0')  (' RHEB%0'  ' STAT3%0')  (' RHEB%0'  ' LIMK2%0')  (' RHEB%0'  ' EP300%0')  (' RHEB%0'  ' STAT1%0')  (' RHEB%0'  ' IKBKB%0')  (' RHEB%0'  ' SRF%0')  (' RHEB%0'  ' PIAS1%0')  (' RHEB%0'  ' TRAF6%0')  (' RHEB%0'  ' SOCS1_g%0')  (' RHEB%0'  ' ISGF3_c%0')  (' RHEB%0'  ' STAT2%0')  (' RHEB%0'  ' CFLAR%0')  (' RHEB%0'  ' SMAD2%0')  (' RHEB%0'  ' MDM2_g%0')  (' RHEB%0'  ' BAX%0')  (' RHEB%0'  ' PRKACA%0')  (' RHEB%0'  ' TGFB1%0')  (' RHEB%0'  ' MAP3K8%0')  (' RHEB%0'  ' TSC_f%0')  (' RHEB%0'  ' SMAD4%0')  (' RHEB%0'  ' BAD%0')  (' RHEB%0'  ' MAP3K5%0')  (' RHEB%0'  ' AKT1S1%0')  (' RHEB%0'  ' SKI%0')  (' RHEB%0'  ' SMAD3%0')  (' RHEB%0'  ' MAPKAPK2%0')  (' RHEB%0'  ' DUSP1_g%0')  (' RHEB%0'  ' MSK_f%0')  (' RHEB%0'  ' GRAP2%0')  (' RHEB%0'  ' TAB_f%0')  (' RHEB%0'  ' ATF2%0')  (' RHEB%0'  ' SMAD5%0')  (' RHEB%0'  ' SMAD1%0')  (' RHEB%0'  ' FOS%0')  (' RHEB%0'  ' JUN%0')  (' RHEB%0'  ' MAP3K7%0')  (' RHEB%0'  ' NLK%0')  (' RHEB%0'  ' SMAD7_g%0')  (' RHEB%0'  ' SMAD6_g%0')  (' RHEB%0'  ' AP1_c%0')  (' RHEB%0'  ' ACVR1%0')  (' RHEB%0'  ' PTPN6%0')  (' RHEB%0'  ' CDC42%0')  (' RHEB%0'  ' GRB2%0')  (' RHEB%0'  ' TGFBR1%0')  (' RHEB%0'  ' SMURF1%0')  (' RHEB%0'  ' SMURF2%0')  (' RHEB%0'  ' RHOA%0')  (' RHEB%0'  ' BMPR2%0')  (' RHEB%0'  ' PARD6A%0')  (' RHEB%0'  ' DAAM1%0')  (' RHEB%0'  ' SFRP1_g%0')  (' RHEB%0'  ' PPM1A%0')  (' RHEB%0'  ' CFL_f%0')  (' RHEB%0'  ' PAK1%0')  (' RHEB%0'  ' MAP3K11%0')  (' RHEB%0'  ' MAP3K4%0')  (' RHEB%0'  ' LIMK1%0')  (' RHEB%0'  ' ROCK1%0')  (' RHEB%0'  ' ITCH%0')  (' RHEB%0'  ' ARHGAP24%0')  (' RHEB%0'  ' TIAM1%0')  (' RHEB%0'  ' RND3%0')  (' RHEB%0'  ' MAPK8IP3%0')  (' RHEB%0'  ' MXD1%0')  (' RHEB%0'  ' PIP3%0')  (' RTPK_g%0'  ' SRC%0')  (' RTPK_g%0'  ' CSK%0')  (' RTPK_g%0'  ' CHUK%0')  (' RTPK_g%0'  ' RAC_f%0')  (' RTPK_g%0'  ' DUSP1%0')  (' RTPK_g%0'  ' TGFBR2%0')  (' RTPK_g%0'  ' ILR_f%0')  (' RTPK_g%0'  ' SYK%0')  (' RTPK_g%0'  ' IRAK1%0')  (' RTPK_g%0'  ' SHC1%0')  (' RTPK_g%0'  ' JAK_f%0')  (' RTPK_g%0'  ' CBPp300_c%0')  (' RTPK_g%0'  ' SKP2%0')  (' RTPK_g%0'  ' TP53%0')  (' RTPK_g%0'  ' SMAD7%0')  (' RTPK_g%0'  ' SMAD6%0')  (' RTPK_g%0'  ' DKK_f%0')  (' RTPK_g%0'  ' FOXO_f%0')  (' RTPK_g%0'  ' TCF7_f%0')  (' RTPK_g%0'  ' DKK_g%0')  (' RTPK_g%0'  ' MYC%0')  (' RTPK_g%0'  ' CCND1%0')  (' RTPK_g%0'  ' EGR1%0')  (' RTPK_g%0'  ' MMP_f%0')  (' RTPK_g%0'  ' PTEN_g%0')  (' RTPK_g%0'  ' RTPK_f%0')  (' RTPK_g%0'  ' CTNNB1%0')  (' RTPK_g%0'  'LEF1%0')  (' RTPK_g%0'  'SFRP1%0')  (' RTPK_g%0'  'FZD_f%0')  (' RTPK_g%0'  ' CASP8%0')  (' RTPK_g%0'  ' REL_f%0')  (' RTPK_g%0'  ' NFKB_f%0')  (' RTPK_g%0'  ' DVL_f%0')  (' RTPK_g%0'  ' LRP_f%0')  (' RTPK_g%0'  ' BTRC%0')  (' RTPK_g%0'  ' CK1_f%0')  (' RTPK_g%0'  ' AXIN1%0')  (' RTPK_g%0'  ' mTORC2_c%0')  (' RTPK_g%0'  ' PDPK1%0')  (' RTPK_g%0'  ' MEK_f%0')  (' RTPK_g%0'  ' CYCS%0')  (' RTPK_g%0'  ' CASP9%0')  (' RTPK_g%0'  ' GSK3_f%0')  (' RTPK_g%0'  ' IRS1%0')  (' RTPK_g%0'  ' MDM2%0')  (' RTPK_g%0'  ' AKT_f%0')  (' RTPK_g%0'  ' BCL2%0')  (' RTPK_g%0'  ' RAF_f%0')  (' RTPK_g%0'  ' mTORC1_c%0')  (' RTPK_g%0'  ' RHEB%0')  (' RTPK_g%0'  ' PTEN%0')  (' RTPK_g%0'  ' CASP3%0')  (' RTPK_g%0'  ' PIK3CA%0')  (' RTPK_g%0'  ' CREBBP%0')  (' RTPK_g%0'  ' PTPN11%0')  (' RTPK_g%0'  ' KRAS%0')  (' RTPK_g%0'  ' MAP2K4%0')  (' RTPK_g%0'  ' MAP2K7%0')  (' RTPK_g%0'  ' MAPK14%0')  (' RTPK_g%0'  ' JNK_f%0')  (' RTPK_g%0'  ' MAP2K3%0')  (' RTPK_g%0'  ' ERK_f%0')  (' RTPK_g%0'  ' LIF%0')  (' RTPK_g%0'  ' PPP1CA%0')  (' RTPK_g%0'  ' GAB_f%0')  (' RTPK_g%0'  ' SOS1%0')  (' RTPK_g%0'  ' PRKCA%0')  (' RTPK_g%0'  ' VAV1%0')  (' RTPK_g%0'  ' PLCG1%0')  (' RTPK_g%0'  ' PRKCD%0')  (' RTPK_g%0'  ' RSK_f%0')  (' RTPK_g%0'  ' S6K_f%0')  (' RTPK_g%0'  ' PLK1%0')  (' RTPK_g%0'  ' ILK%0')  (' RTPK_g%0'  ' SOCS1%0')  (' RTPK_g%0'  ' DUSP6%0')  (' RTPK_g%0'  ' STAT3%0')  (' RTPK_g%0'  ' LIMK2%0')  (' RTPK_g%0'  ' EP300%0')  (' RTPK_g%0'  ' STAT1%0')  (' RTPK_g%0'  ' IKBKB%0')  (' RTPK_g%0'  ' SRF%0')  (' RTPK_g%0'  ' PIAS1%0')  (' RTPK_g%0'  ' TRAF6%0')  (' RTPK_g%0'  ' SOCS1_g%0')  (' RTPK_g%0'  ' ISGF3_c%0')  (' RTPK_g%0'  ' STAT2%0')  (' RTPK_g%0'  ' CFLAR%0')  (' RTPK_g%0'  ' SMAD2%0')  (' RTPK_g%0'  ' MDM2_g%0')  (' RTPK_g%0'  ' BAX%0')  (' RTPK_g%0'  ' PRKACA%0')  (' RTPK_g%0'  ' TGFB1%0')  (' RTPK_g%0'  ' MAP3K8%0')  (' RTPK_g%0'  ' TSC_f%0')  (' RTPK_g%0'  ' SMAD4%0')  (' RTPK_g%0'  ' BAD%0')  (' RTPK_g%0'  ' MAP3K5%0')  (' RTPK_g%0'  ' AKT1S1%0')  (' RTPK_g%0'  ' SKI%0')  (' RTPK_g%0'  ' SMAD3%0')  (' RTPK_g%0'  ' MAPKAPK2%0')  (' RTPK_g%0'  ' DUSP1_g%0')  (' RTPK_g%0'  ' MSK_f%0')  (' RTPK_g%0'  ' GRAP2%0')  (' RTPK_g%0'  ' TAB_f%0')  (' RTPK_g%0'  ' ATF2%0')  (' RTPK_g%0'  ' SMAD5%0')  (' RTPK_g%0'  ' SMAD1%0')  (' RTPK_g%0'  ' FOS%0')  (' RTPK_g%0'  ' JUN%0')  (' RTPK_g%0'  ' MAP3K7%0')  (' RTPK_g%0'  ' NLK%0')  (' RTPK_g%0'  ' SMAD7_g%0')  (' RTPK_g%0'  ' SMAD6_g%0')  (' RTPK_g%0'  ' AP1_c%0')  (' RTPK_g%0'  ' ACVR1%0')  (' RTPK_g%0'  ' PTPN6%0')  (' RTPK_g%0'  ' CDC42%0')  (' RTPK_g%0'  ' GRB2%0')  (' RTPK_g%0'  ' TGFBR1%0')  (' RTPK_g%0'  ' SMURF1%0')  (' RTPK_g%0'  ' SMURF2%0')  (' RTPK_g%0'  ' RHOA%0')  (' RTPK_g%0'  ' BMPR2%0')  (' RTPK_g%0'  ' PARD6A%0')  (' RTPK_g%0'  ' DAAM1%0')  (' RTPK_g%0'  ' SFRP1_g%0')  (' RTPK_g%0'  ' PPM1A%0')  (' RTPK_g%0'  ' CFL_f%0')  (' RTPK_g%0'  ' PAK1%0')  (' RTPK_g%0'  ' MAP3K11%0')  (' RTPK_g%0'  ' MAP3K4%0')  (' RTPK_g%0'  ' LIMK1%0')  (' RTPK_g%0'  ' ROCK1%0')  (' RTPK_g%0'  ' ITCH%0')  (' RTPK_g%0'  ' ARHGAP24%0')  (' RTPK_g%0'  ' TIAM1%0')  (' RTPK_g%0'  ' RND3%0')  (' RTPK_g%0'  ' MAPK8IP3%0')  (' RTPK_g%0'  ' MXD1%0')  (' RTPK_g%0'  ' PIP3%0')  (' PTEN%0'  ' SRC%0')  (' PTEN%0'  ' CSK%0')  (' PTEN%0'  ' CHUK%0')  (' PTEN%0'  ' RAC_f%0')  (' PTEN%0'  ' DUSP1%0')  (' PTEN%0'  ' TGFBR2%0')  (' PTEN%0'  ' ILR_f%0')  (' PTEN%0'  ' SYK%0')  (' PTEN%0'  ' IRAK1%0')  (' PTEN%0'  ' SHC1%0')  (' PTEN%0'  ' JAK_f%0')  (' PTEN%0'  ' CBPp300_c%0')  (' PTEN%0'  ' SKP2%0')  (' PTEN%0'  ' TP53%0')  (' PTEN%0'  ' SMAD7%0')  (' PTEN%0'  ' SMAD6%0')  (' PTEN%0'  ' DKK_f%0')  (' PTEN%0'  ' FOXO_f%0')  (' PTEN%0'  ' TCF7_f%0')  (' PTEN%0'  ' DKK_g%0')  (' PTEN%0'  ' MYC%0')  (' PTEN%0'  ' CCND1%0')  (' PTEN%0'  ' EGR1%0')  (' PTEN%0'  ' MMP_f%0')  (' PTEN%0'  ' PTEN_g%0')  (' PTEN%0'  ' RTPK_f%0')  (' PTEN%0'  ' CTNNB1%0')  (' PTEN%0'  'LEF1%0')  (' PTEN%0'  'SFRP1%0')  (' PTEN%0'  'FZD_f%0')  (' PTEN%0'  ' CASP8%0')  (' PTEN%0'  ' REL_f%0')  (' PTEN%0'  ' NFKB_f%0')  (' PTEN%0'  ' DVL_f%0')  (' PTEN%0'  ' LRP_f%0')  (' PTEN%0'  ' BTRC%0')  (' PTEN%0'  ' CK1_f%0')  (' PTEN%0'  ' AXIN1%0')  (' PTEN%0'  ' mTORC2_c%0')  (' PTEN%0'  ' PDPK1%0')  (' PTEN%0'  ' MEK_f%0')  (' PTEN%0'  ' CYCS%0')  (' PTEN%0'  ' CASP9%0')  (' PTEN%0'  ' GSK3_f%0')  (' PTEN%0'  ' IRS1%0')  (' PTEN%0'  ' MDM2%0')  (' PTEN%0'  ' AKT_f%0')  (' PTEN%0'  ' BCL2%0')  (' PTEN%0'  ' RAF_f%0')  (' PTEN%0'  ' mTORC1_c%0')  (' PTEN%0'  ' RHEB%0')  (' PTEN%0'  ' RTPK_g%0')  (' PTEN%0'  ' CASP3%0')  (' PTEN%0'  ' PIK3CA%0')  (' PTEN%0'  ' CREBBP%0')  (' PTEN%0'  ' PTPN11%0')  (' PTEN%0'  ' KRAS%0')  (' PTEN%0'  ' MAP2K4%0')  (' PTEN%0'  ' MAP2K7%0')  (' PTEN%0'  ' MAPK14%0')  (' PTEN%0'  ' JNK_f%0')  (' PTEN%0'  ' MAP2K3%0')  (' PTEN%0'  ' ERK_f%0')  (' PTEN%0'  ' LIF%0')  (' PTEN%0'  ' PPP1CA%0')  (' PTEN%0'  ' GAB_f%0')  (' PTEN%0'  ' SOS1%0')  (' PTEN%0'  ' PRKCA%0')  (' PTEN%0'  ' VAV1%0')  (' PTEN%0'  ' PLCG1%0')  (' PTEN%0'  ' PRKCD%0')  (' PTEN%0'  ' RSK_f%0')  (' PTEN%0'  ' S6K_f%0')  (' PTEN%0'  ' PLK1%0')  (' PTEN%0'  ' ILK%0')  (' PTEN%0'  ' SOCS1%0')  (' PTEN%0'  ' DUSP6%0')  (' PTEN%0'  ' STAT3%0')  (' PTEN%0'  ' LIMK2%0')  (' PTEN%0'  ' EP300%0')  (' PTEN%0'  ' STAT1%0')  (' PTEN%0'  ' IKBKB%0')  (' PTEN%0'  ' SRF%0')  (' PTEN%0'  ' PIAS1%0')  (' PTEN%0'  ' TRAF6%0')  (' PTEN%0'  ' SOCS1_g%0')  (' PTEN%0'  ' ISGF3_c%0')  (' PTEN%0'  ' STAT2%0')  (' PTEN%0'  ' CFLAR%0')  (' PTEN%0'  ' SMAD2%0')  (' PTEN%0'  ' MDM2_g%0')  (' PTEN%0'  ' BAX%0')  (' PTEN%0'  ' PRKACA%0')  (' PTEN%0'  ' TGFB1%0')  (' PTEN%0'  ' MAP3K8%0')  (' PTEN%0'  ' TSC_f%0')  (' PTEN%0'  ' SMAD4%0')  (' PTEN%0'  ' BAD%0')  (' PTEN%0'  ' MAP3K5%0')  (' PTEN%0'  ' AKT1S1%0')  (' PTEN%0'  ' SKI%0')  (' PTEN%0'  ' SMAD3%0')  (' PTEN%0'  ' MAPKAPK2%0')  (' PTEN%0'  ' DUSP1_g%0')  (' PTEN%0'  ' MSK_f%0')  (' PTEN%0'  ' GRAP2%0')  (' PTEN%0'  ' TAB_f%0')  (' PTEN%0'  ' ATF2%0')  (' PTEN%0'  ' SMAD5%0')  (' PTEN%0'  ' SMAD1%0')  (' PTEN%0'  ' FOS%0')  (' PTEN%0'  ' JUN%0')  (' PTEN%0'  ' MAP3K7%0')  (' PTEN%0'  ' NLK%0')  (' PTEN%0'  ' SMAD7_g%0')  (' PTEN%0'  ' SMAD6_g%0')  (' PTEN%0'  ' AP1_c%0')  (' PTEN%0'  ' ACVR1%0')  (' PTEN%0'  ' PTPN6%0')  (' PTEN%0'  ' CDC42%0')  (' PTEN%0'  ' GRB2%0')  (' PTEN%0'  ' TGFBR1%0')  (' PTEN%0'  ' SMURF1%0')  (' PTEN%0'  ' SMURF2%0')  (' PTEN%0'  ' RHOA%0')  (' PTEN%0'  ' BMPR2%0')  (' PTEN%0'  ' PARD6A%0')  (' PTEN%0'  ' DAAM1%0')  (' PTEN%0'  ' SFRP1_g%0')  (' PTEN%0'  ' PPM1A%0')  (' PTEN%0'  ' CFL_f%0')  (' PTEN%0'  ' PAK1%0')  (' PTEN%0'  ' MAP3K11%0')  (' PTEN%0'  ' MAP3K4%0')  (' PTEN%0'  ' LIMK1%0')  (' PTEN%0'  ' ROCK1%0')  (' PTEN%0'  ' ITCH%0')  (' PTEN%0'  ' ARHGAP24%0')  (' PTEN%0'  ' TIAM1%0')  (' PTEN%0'  ' RND3%0')  (' PTEN%0'  ' MAPK8IP3%0')  (' PTEN%0'  ' MXD1%0')  (' PTEN%0'  ' PIP3%0')  (' CASP3%0'  ' SRC%0')  (' CASP3%0'  ' CSK%0')  (' CASP3%0'  ' CHUK%0')  (' CASP3%0'  ' RAC_f%0')  (' CASP3%0'  ' DUSP1%0')  (' CASP3%0'  ' TGFBR2%0')  (' CASP3%0'  ' ILR_f%0')  (' CASP3%0'  ' SYK%0')  (' CASP3%0'  ' IRAK1%0')  (' CASP3%0'  ' SHC1%0')  (' CASP3%0'  ' JAK_f%0')  (' CASP3%0'  ' CBPp300_c%0')  (' CASP3%0'  ' SKP2%0')  (' CASP3%0'  ' TP53%0')  (' CASP3%0'  ' SMAD7%0')  (' CASP3%0'  ' SMAD6%0')  (' CASP3%0'  ' DKK_f%0')  (' CASP3%0'  ' FOXO_f%0')  (' CASP3%0'  ' TCF7_f%0')  (' CASP3%0'  ' DKK_g%0')  (' CASP3%0'  ' MYC%0')  (' CASP3%0'  ' CCND1%0')  (' CASP3%0'  ' EGR1%0')  (' CASP3%0'  ' MMP_f%0')  (' CASP3%0'  ' PTEN_g%0')  (' CASP3%0'  ' RTPK_f%0')  (' CASP3%0'  ' CTNNB1%0')  (' CASP3%0'  'LEF1%0')  (' CASP3%0'  'SFRP1%0')  (' CASP3%0'  'FZD_f%0')  (' CASP3%0'  ' CASP8%0')  (' CASP3%0'  ' REL_f%0')  (' CASP3%0'  ' NFKB_f%0')  (' CASP3%0'  ' DVL_f%0')  (' CASP3%0'  ' LRP_f%0')  (' CASP3%0'  ' BTRC%0')  (' CASP3%0'  ' CK1_f%0')  (' CASP3%0'  ' AXIN1%0')  (' CASP3%0'  ' mTORC2_c%0')  (' CASP3%0'  ' PDPK1%0')  (' CASP3%0'  ' MEK_f%0')  (' CASP3%0'  ' CYCS%0')  (' CASP3%0'  ' CASP9%0')  (' CASP3%0'  ' GSK3_f%0')  (' CASP3%0'  ' IRS1%0')  (' CASP3%0'  ' MDM2%0')  (' CASP3%0'  ' AKT_f%0')  (' CASP3%0'  ' BCL2%0')  (' CASP3%0'  ' RAF_f%0')  (' CASP3%0'  ' mTORC1_c%0')  (' CASP3%0'  ' RHEB%0')  (' CASP3%0'  ' RTPK_g%0')  (' CASP3%0'  ' PTEN%0')  (' CASP3%0'  ' PIK3CA%0')  (' CASP3%0'  ' CREBBP%0')  (' CASP3%0'  ' PTPN11%0')  (' CASP3%0'  ' KRAS%0')  (' CASP3%0'  ' MAP2K4%0')  (' CASP3%0'  ' MAP2K7%0')  (' CASP3%0'  ' MAPK14%0')  (' CASP3%0'  ' JNK_f%0')  (' CASP3%0'  ' MAP2K3%0')  (' CASP3%0'  ' ERK_f%0')  (' CASP3%0'  ' LIF%0')  (' CASP3%0'  ' PPP1CA%0')  (' CASP3%0'  ' GAB_f%0')  (' CASP3%0'  ' SOS1%0')  (' CASP3%0'  ' PRKCA%0')  (' CASP3%0'  ' VAV1%0')  (' CASP3%0'  ' PLCG1%0')  (' CASP3%0'  ' PRKCD%0')  (' CASP3%0'  ' RSK_f%0')  (' CASP3%0'  ' S6K_f%0')  (' CASP3%0'  ' PLK1%0')  (' CASP3%0'  ' ILK%0')  (' CASP3%0'  ' SOCS1%0')  (' CASP3%0'  ' DUSP6%0')  (' CASP3%0'  ' STAT3%0')  (' CASP3%0'  ' LIMK2%0')  (' CASP3%0'  ' EP300%0')  (' CASP3%0'  ' STAT1%0')  (' CASP3%0'  ' IKBKB%0')  (' CASP3%0'  ' SRF%0')  (' CASP3%0'  ' PIAS1%0')  (' CASP3%0'  ' TRAF6%0')  (' CASP3%0'  ' SOCS1_g%0')  (' CASP3%0'  ' ISGF3_c%0')  (' CASP3%0'  ' STAT2%0')  (' CASP3%0'  ' CFLAR%0')  (' CASP3%0'  ' SMAD2%0')  (' CASP3%0'  ' MDM2_g%0')  (' CASP3%0'  ' BAX%0')  (' CASP3%0'  ' PRKACA%0')  (' CASP3%0'  ' TGFB1%0')  (' CASP3%0'  ' MAP3K8%0')  (' CASP3%0'  ' TSC_f%0')  (' CASP3%0'  ' SMAD4%0')  (' CASP3%0'  ' BAD%0')  (' CASP3%0'  ' MAP3K5%0')  (' CASP3%0'  ' AKT1S1%0')  (' CASP3%0'  ' SKI%0')  (' CASP3%0'  ' SMAD3%0')  (' CASP3%0'  ' MAPKAPK2%0')  (' CASP3%0'  ' DUSP1_g%0')  (' CASP3%0'  ' MSK_f%0')  (' CASP3%0'  ' GRAP2%0')  (' CASP3%0'  ' TAB_f%0')  (' CASP3%0'  ' ATF2%0')  (' CASP3%0'  ' SMAD5%0')  (' CASP3%0'  ' SMAD1%0')  (' CASP3%0'  ' FOS%0')  (' CASP3%0'  ' JUN%0')  (' CASP3%0'  ' MAP3K7%0')  (' CASP3%0'  ' NLK%0')  (' CASP3%0'  ' SMAD7_g%0')  (' CASP3%0'  ' SMAD6_g%0')  (' CASP3%0'  ' AP1_c%0')  (' CASP3%0'  ' ACVR1%0')  (' CASP3%0'  ' PTPN6%0')  (' CASP3%0'  ' CDC42%0')  (' CASP3%0'  ' GRB2%0')  (' CASP3%0'  ' TGFBR1%0')  (' CASP3%0'  ' SMURF1%0')  (' CASP3%0'  ' SMURF2%0')  (' CASP3%0'  ' RHOA%0')  (' CASP3%0'  ' BMPR2%0')  (' CASP3%0'  ' PARD6A%0')  (' CASP3%0'  ' DAAM1%0')  (' CASP3%0'  ' SFRP1_g%0')  (' CASP3%0'  ' PPM1A%0')  (' CASP3%0'  ' CFL_f%0')  (' CASP3%0'  ' PAK1%0')  (' CASP3%0'  ' MAP3K11%0')  (' CASP3%0'  ' MAP3K4%0')  (' CASP3%0'  ' LIMK1%0')  (' CASP3%0'  ' ROCK1%0')  (' CASP3%0'  ' ITCH%0')  (' CASP3%0'  ' ARHGAP24%0')  (' CASP3%0'  ' TIAM1%0')  (' CASP3%0'  ' RND3%0')  (' CASP3%0'  ' MAPK8IP3%0')  (' CASP3%0'  ' MXD1%0')  (' CASP3%0'  ' PIP3%0')  (' PIK3CA%0'  ' SRC%0')  (' PIK3CA%0'  ' CSK%0')  (' PIK3CA%0'  ' CHUK%0')  (' PIK3CA%0'  ' RAC_f%0')  (' PIK3CA%0'  ' DUSP1%0')  (' PIK3CA%0'  ' TGFBR2%0')  (' PIK3CA%0'  ' ILR_f%0')  (' PIK3CA%0'  ' SYK%0')  (' PIK3CA%0'  ' IRAK1%0')  (' PIK3CA%0'  ' SHC1%0')  (' PIK3CA%0'  ' JAK_f%0')  (' PIK3CA%0'  ' CBPp300_c%0')  (' PIK3CA%0'  ' SKP2%0')  (' PIK3CA%0'  ' TP53%0')  (' PIK3CA%0'  ' SMAD7%0')  (' PIK3CA%0'  ' SMAD6%0')  (' PIK3CA%0'  ' DKK_f%0')  (' PIK3CA%0'  ' FOXO_f%0')  (' PIK3CA%0'  ' TCF7_f%0')  (' PIK3CA%0'  ' DKK_g%0')  (' PIK3CA%0'  ' MYC%0')  (' PIK3CA%0'  ' CCND1%0')  (' PIK3CA%0'  ' EGR1%0')  (' PIK3CA%0'  ' MMP_f%0')  (' PIK3CA%0'  ' PTEN_g%0')  (' PIK3CA%0'  ' RTPK_f%0')  (' PIK3CA%0'  ' CTNNB1%0')  (' PIK3CA%0'  'LEF1%0')  (' PIK3CA%0'  'SFRP1%0')  (' PIK3CA%0'  'FZD_f%0')  (' PIK3CA%0'  ' CASP8%0')  (' PIK3CA%0'  ' REL_f%0')  (' PIK3CA%0'  ' NFKB_f%0')  (' PIK3CA%0'  ' DVL_f%0')  (' PIK3CA%0'  ' LRP_f%0')  (' PIK3CA%0'  ' BTRC%0')  (' PIK3CA%0'  ' CK1_f%0')  (' PIK3CA%0'  ' AXIN1%0')  (' PIK3CA%0'  ' mTORC2_c%0')  (' PIK3CA%0'  ' PDPK1%0')  (' PIK3CA%0'  ' MEK_f%0')  (' PIK3CA%0'  ' CYCS%0')  (' PIK3CA%0'  ' CASP9%0')  (' PIK3CA%0'  ' GSK3_f%0')  (' PIK3CA%0'  ' IRS1%0')  (' PIK3CA%0'  ' MDM2%0')  (' PIK3CA%0'  ' AKT_f%0')  (' PIK3CA%0'  ' BCL2%0')  (' PIK3CA%0'  ' RAF_f%0')  (' PIK3CA%0'  ' mTORC1_c%0')  (' PIK3CA%0'  ' RHEB%0')  (' PIK3CA%0'  ' RTPK_g%0')  (' PIK3CA%0'  ' PTEN%0')  (' PIK3CA%0'  ' CASP3%0')  (' PIK3CA%0'  ' CREBBP%0')  (' PIK3CA%0'  ' PTPN11%0')  (' PIK3CA%0'  ' KRAS%0')  (' PIK3CA%0'  ' MAP2K4%0')  (' PIK3CA%0'  ' MAP2K7%0')  (' PIK3CA%0'  ' MAPK14%0')  (' PIK3CA%0'  ' JNK_f%0')  (' PIK3CA%0'  ' MAP2K3%0')  (' PIK3CA%0'  ' ERK_f%0')  (' PIK3CA%0'  ' LIF%0')  (' PIK3CA%0'  ' PPP1CA%0')  (' PIK3CA%0'  ' GAB_f%0')  (' PIK3CA%0'  ' SOS1%0')  (' PIK3CA%0'  ' PRKCA%0')  (' PIK3CA%0'  ' VAV1%0')  (' PIK3CA%0'  ' PLCG1%0')  (' PIK3CA%0'  ' PRKCD%0')  (' PIK3CA%0'  ' RSK_f%0')  (' PIK3CA%0'  ' S6K_f%0')  (' PIK3CA%0'  ' PLK1%0')  (' PIK3CA%0'  ' ILK%0')  (' PIK3CA%0'  ' SOCS1%0')  (' PIK3CA%0'  ' DUSP6%0')  (' PIK3CA%0'  ' STAT3%0')  (' PIK3CA%0'  ' LIMK2%0')  (' PIK3CA%0'  ' EP300%0')  (' PIK3CA%0'  ' STAT1%0')  (' PIK3CA%0'  ' IKBKB%0')  (' PIK3CA%0'  ' SRF%0')  (' PIK3CA%0'  ' PIAS1%0')  (' PIK3CA%0'  ' TRAF6%0')  (' PIK3CA%0'  ' SOCS1_g%0')  (' PIK3CA%0'  ' ISGF3_c%0')  (' PIK3CA%0'  ' STAT2%0')  (' PIK3CA%0'  ' CFLAR%0')  (' PIK3CA%0'  ' SMAD2%0')  (' PIK3CA%0'  ' MDM2_g%0')  (' PIK3CA%0'  ' BAX%0')  (' PIK3CA%0'  ' PRKACA%0')  (' PIK3CA%0'  ' TGFB1%0')  (' PIK3CA%0'  ' MAP3K8%0')  (' PIK3CA%0'  ' TSC_f%0')  (' PIK3CA%0'  ' SMAD4%0')  (' PIK3CA%0'  ' BAD%0')  (' PIK3CA%0'  ' MAP3K5%0')  (' PIK3CA%0'  ' AKT1S1%0')  (' PIK3CA%0'  ' SKI%0')  (' PIK3CA%0'  ' SMAD3%0')  (' PIK3CA%0'  ' MAPKAPK2%0')  (' PIK3CA%0'  ' DUSP1_g%0')  (' PIK3CA%0'  ' MSK_f%0')  (' PIK3CA%0'  ' GRAP2%0')  (' PIK3CA%0'  ' TAB_f%0')  (' PIK3CA%0'  ' ATF2%0')  (' PIK3CA%0'  ' SMAD5%0')  (' PIK3CA%0'  ' SMAD1%0')  (' PIK3CA%0'  ' FOS%0')  (' PIK3CA%0'  ' JUN%0')  (' PIK3CA%0'  ' MAP3K7%0')  (' PIK3CA%0'  ' NLK%0')  (' PIK3CA%0'  ' SMAD7_g%0')  (' PIK3CA%0'  ' SMAD6_g%0')  (' PIK3CA%0'  ' AP1_c%0')  (' PIK3CA%0'  ' ACVR1%0')  (' PIK3CA%0'  ' PTPN6%0')  (' PIK3CA%0'  ' CDC42%0')  (' PIK3CA%0'  ' GRB2%0')  (' PIK3CA%0'  ' TGFBR1%0')  (' PIK3CA%0'  ' SMURF1%0')  (' PIK3CA%0'  ' SMURF2%0')  (' PIK3CA%0'  ' RHOA%0')  (' PIK3CA%0'  ' BMPR2%0')  (' PIK3CA%0'  ' PARD6A%0')  (' PIK3CA%0'  ' DAAM1%0')  (' PIK3CA%0'  ' SFRP1_g%0')  (' PIK3CA%0'  ' PPM1A%0')  (' PIK3CA%0'  ' CFL_f%0')  (' PIK3CA%0'  ' PAK1%0')  (' PIK3CA%0'  ' MAP3K11%0')  (' PIK3CA%0'  ' MAP3K4%0')  (' PIK3CA%0'  ' LIMK1%0')  (' PIK3CA%0'  ' ROCK1%0')  (' PIK3CA%0'  ' ITCH%0')  (' PIK3CA%0'  ' ARHGAP24%0')  (' PIK3CA%0'  ' TIAM1%0')  (' PIK3CA%0'  ' RND3%0')  (' PIK3CA%0'  ' MAPK8IP3%0')  (' PIK3CA%0'  ' MXD1%0')  (' PIK3CA%0'  ' PIP3%0')  (' CREBBP%0'  ' SRC%0')  (' CREBBP%0'  ' CSK%0')  (' CREBBP%0'  ' CHUK%0')  (' CREBBP%0'  ' RAC_f%0')  (' CREBBP%0'  ' DUSP1%0')  (' CREBBP%0'  ' TGFBR2%0')  (' CREBBP%0'  ' ILR_f%0')  (' CREBBP%0'  ' SYK%0')  (' CREBBP%0'  ' IRAK1%0')  (' CREBBP%0'  ' SHC1%0')  (' CREBBP%0'  ' JAK_f%0')  (' CREBBP%0'  ' CBPp300_c%0')  (' CREBBP%0'  ' SKP2%0')  (' CREBBP%0'  ' TP53%0')  (' CREBBP%0'  ' SMAD7%0')  (' CREBBP%0'  ' SMAD6%0')  (' CREBBP%0'  ' DKK_f%0')  (' CREBBP%0'  ' FOXO_f%0')  (' CREBBP%0'  ' TCF7_f%0')  (' CREBBP%0'  ' DKK_g%0')  (' CREBBP%0'  ' MYC%0')  (' CREBBP%0'  ' CCND1%0')  (' CREBBP%0'  ' EGR1%0')  (' CREBBP%0'  ' MMP_f%0')  (' CREBBP%0'  ' PTEN_g%0')  (' CREBBP%0'  ' RTPK_f%0')  (' CREBBP%0'  ' CTNNB1%0')  (' CREBBP%0'  'LEF1%0')  (' CREBBP%0'  'SFRP1%0')  (' CREBBP%0'  'FZD_f%0')  (' CREBBP%0'  ' CASP8%0')  (' CREBBP%0'  ' REL_f%0')  (' CREBBP%0'  ' NFKB_f%0')  (' CREBBP%0'  ' DVL_f%0')  (' CREBBP%0'  ' LRP_f%0')  (' CREBBP%0'  ' BTRC%0')  (' CREBBP%0'  ' CK1_f%0')  (' CREBBP%0'  ' AXIN1%0')  (' CREBBP%0'  ' mTORC2_c%0')  (' CREBBP%0'  ' PDPK1%0')  (' CREBBP%0'  ' MEK_f%0')  (' CREBBP%0'  ' CYCS%0')  (' CREBBP%0'  ' CASP9%0')  (' CREBBP%0'  ' GSK3_f%0')  (' CREBBP%0'  ' IRS1%0')  (' CREBBP%0'  ' MDM2%0')  (' CREBBP%0'  ' AKT_f%0')  (' CREBBP%0'  ' BCL2%0')  (' CREBBP%0'  ' RAF_f%0')  (' CREBBP%0'  ' mTORC1_c%0')  (' CREBBP%0'  ' RHEB%0')  (' CREBBP%0'  ' RTPK_g%0')  (' CREBBP%0'  ' PTEN%0')  (' CREBBP%0'  ' CASP3%0')  (' CREBBP%0'  ' PIK3CA%0')  (' CREBBP%0'  ' PTPN11%0')  (' CREBBP%0'  ' KRAS%0')  (' CREBBP%0'  ' MAP2K4%0')  (' CREBBP%0'  ' MAP2K7%0')  (' CREBBP%0'  ' MAPK14%0')  (' CREBBP%0'  ' JNK_f%0')  (' CREBBP%0'  ' MAP2K3%0')  (' CREBBP%0'  ' ERK_f%0')  (' CREBBP%0'  ' LIF%0')  (' CREBBP%0'  ' PPP1CA%0')  (' CREBBP%0'  ' GAB_f%0')  (' CREBBP%0'  ' SOS1%0')  (' CREBBP%0'  ' PRKCA%0')  (' CREBBP%0'  ' VAV1%0')  (' CREBBP%0'  ' PLCG1%0')  (' CREBBP%0'  ' PRKCD%0')  (' CREBBP%0'  ' RSK_f%0')  (' CREBBP%0'  ' S6K_f%0')  (' CREBBP%0'  ' PLK1%0')  (' CREBBP%0'  ' ILK%0')  (' CREBBP%0'  ' SOCS1%0')  (' CREBBP%0'  ' DUSP6%0')  (' CREBBP%0'  ' STAT3%0')  (' CREBBP%0'  ' LIMK2%0')  (' CREBBP%0'  ' EP300%0')  (' CREBBP%0'  ' STAT1%0')  (' CREBBP%0'  ' IKBKB%0')  (' CREBBP%0'  ' SRF%0')  (' CREBBP%0'  ' PIAS1%0')  (' CREBBP%0'  ' TRAF6%0')  (' CREBBP%0'  ' SOCS1_g%0')  (' CREBBP%0'  ' ISGF3_c%0')  (' CREBBP%0'  ' STAT2%0')  (' CREBBP%0'  ' CFLAR%0')  (' CREBBP%0'  ' SMAD2%0')  (' CREBBP%0'  ' MDM2_g%0')  (' CREBBP%0'  ' BAX%0')  (' CREBBP%0'  ' PRKACA%0')  (' CREBBP%0'  ' TGFB1%0')  (' CREBBP%0'  ' MAP3K8%0')  (' CREBBP%0'  ' TSC_f%0')  (' CREBBP%0'  ' SMAD4%0')  (' CREBBP%0'  ' BAD%0')  (' CREBBP%0'  ' MAP3K5%0')  (' CREBBP%0'  ' AKT1S1%0')  (' CREBBP%0'  ' SKI%0')  (' CREBBP%0'  ' SMAD3%0')  (' CREBBP%0'  ' MAPKAPK2%0')  (' CREBBP%0'  ' DUSP1_g%0')  (' CREBBP%0'  ' MSK_f%0')  (' CREBBP%0'  ' GRAP2%0')  (' CREBBP%0'  ' TAB_f%0')  (' CREBBP%0'  ' ATF2%0')  (' CREBBP%0'  ' SMAD5%0')  (' CREBBP%0'  ' SMAD1%0')  (' CREBBP%0'  ' FOS%0')  (' CREBBP%0'  ' JUN%0')  (' CREBBP%0'  ' MAP3K7%0')  (' CREBBP%0'  ' NLK%0')  (' CREBBP%0'  ' SMAD7_g%0')  (' CREBBP%0'  ' SMAD6_g%0')  (' CREBBP%0'  ' AP1_c%0')  (' CREBBP%0'  ' ACVR1%0')  (' CREBBP%0'  ' PTPN6%0')  (' CREBBP%0'  ' CDC42%0')  (' CREBBP%0'  ' GRB2%0')  (' CREBBP%0'  ' TGFBR1%0')  (' CREBBP%0'  ' SMURF1%0')  (' CREBBP%0'  ' SMURF2%0')  (' CREBBP%0'  ' RHOA%0')  (' CREBBP%0'  ' BMPR2%0')  (' CREBBP%0'  ' PARD6A%0')  (' CREBBP%0'  ' DAAM1%0')  (' CREBBP%0'  ' SFRP1_g%0')  (' CREBBP%0'  ' PPM1A%0')  (' CREBBP%0'  ' CFL_f%0')  (' CREBBP%0'  ' PAK1%0')  (' CREBBP%0'  ' MAP3K11%0')  (' CREBBP%0'  ' MAP3K4%0')  (' CREBBP%0'  ' LIMK1%0')  (' CREBBP%0'  ' ROCK1%0')  (' CREBBP%0'  ' ITCH%0')  (' CREBBP%0'  ' ARHGAP24%0')  (' CREBBP%0'  ' TIAM1%0')  (' CREBBP%0'  ' RND3%0')  (' CREBBP%0'  ' MAPK8IP3%0')  (' CREBBP%0'  ' MXD1%0')  (' CREBBP%0'  ' PIP3%0')  (' PTPN11%0'  ' SRC%0')  (' PTPN11%0'  ' CSK%0')  (' PTPN11%0'  ' CHUK%0')  (' PTPN11%0'  ' RAC_f%0')  (' PTPN11%0'  ' DUSP1%0')  (' PTPN11%0'  ' TGFBR2%0')  (' PTPN11%0'  ' ILR_f%0')  (' PTPN11%0'  ' SYK%0')  (' PTPN11%0'  ' IRAK1%0')  (' PTPN11%0'  ' SHC1%0')  (' PTPN11%0'  ' JAK_f%0')  (' PTPN11%0'  ' CBPp300_c%0')  (' PTPN11%0'  ' SKP2%0')  (' PTPN11%0'  ' TP53%0')  (' PTPN11%0'  ' SMAD7%0')  (' PTPN11%0'  ' SMAD6%0')  (' PTPN11%0'  ' DKK_f%0')  (' PTPN11%0'  ' FOXO_f%0')  (' PTPN11%0'  ' TCF7_f%0')  (' PTPN11%0'  ' DKK_g%0')  (' PTPN11%0'  ' MYC%0')  (' PTPN11%0'  ' CCND1%0')  (' PTPN11%0'  ' EGR1%0')  (' PTPN11%0'  ' MMP_f%0')  (' PTPN11%0'  ' PTEN_g%0')  (' PTPN11%0'  ' RTPK_f%0')  (' PTPN11%0'  ' CTNNB1%0')  (' PTPN11%0'  'LEF1%0')  (' PTPN11%0'  'SFRP1%0')  (' PTPN11%0'  'FZD_f%0')  (' PTPN11%0'  ' CASP8%0')  (' PTPN11%0'  ' REL_f%0')  (' PTPN11%0'  ' NFKB_f%0')  (' PTPN11%0'  ' DVL_f%0')  (' PTPN11%0'  ' LRP_f%0')  (' PTPN11%0'  ' BTRC%0')  (' PTPN11%0'  ' CK1_f%0')  (' PTPN11%0'  ' AXIN1%0')  (' PTPN11%0'  ' mTORC2_c%0')  (' PTPN11%0'  ' PDPK1%0')  (' PTPN11%0'  ' MEK_f%0')  (' PTPN11%0'  ' CYCS%0')  (' PTPN11%0'  ' CASP9%0')  (' PTPN11%0'  ' GSK3_f%0')  (' PTPN11%0'  ' IRS1%0')  (' PTPN11%0'  ' MDM2%0')  (' PTPN11%0'  ' AKT_f%0')  (' PTPN11%0'  ' BCL2%0')  (' PTPN11%0'  ' RAF_f%0')  (' PTPN11%0'  ' mTORC1_c%0')  (' PTPN11%0'  ' RHEB%0')  (' PTPN11%0'  ' RTPK_g%0')  (' PTPN11%0'  ' PTEN%0')  (' PTPN11%0'  ' CASP3%0')  (' PTPN11%0'  ' PIK3CA%0')  (' PTPN11%0'  ' CREBBP%0')  (' PTPN11%0'  ' KRAS%0')  (' PTPN11%0'  ' MAP2K4%0')  (' PTPN11%0'  ' MAP2K7%0')  (' PTPN11%0'  ' MAPK14%0')  (' PTPN11%0'  ' JNK_f%0')  (' PTPN11%0'  ' MAP2K3%0')  (' PTPN11%0'  ' ERK_f%0')  (' PTPN11%0'  ' LIF%0')  (' PTPN11%0'  ' PPP1CA%0')  (' PTPN11%0'  ' GAB_f%0')  (' PTPN11%0'  ' SOS1%0')  (' PTPN11%0'  ' PRKCA%0')  (' PTPN11%0'  ' VAV1%0')  (' PTPN11%0'  ' PLCG1%0')  (' PTPN11%0'  ' PRKCD%0')  (' PTPN11%0'  ' RSK_f%0')  (' PTPN11%0'  ' S6K_f%0')  (' PTPN11%0'  ' PLK1%0')  (' PTPN11%0'  ' ILK%0')  (' PTPN11%0'  ' SOCS1%0')  (' PTPN11%0'  ' DUSP6%0')  (' PTPN11%0'  ' STAT3%0')  (' PTPN11%0'  ' LIMK2%0')  (' PTPN11%0'  ' EP300%0')  (' PTPN11%0'  ' STAT1%0')  (' PTPN11%0'  ' IKBKB%0')  (' PTPN11%0'  ' SRF%0')  (' PTPN11%0'  ' PIAS1%0')  (' PTPN11%0'  ' TRAF6%0')  (' PTPN11%0'  ' SOCS1_g%0')  (' PTPN11%0'  ' ISGF3_c%0')  (' PTPN11%0'  ' STAT2%0')  (' PTPN11%0'  ' CFLAR%0')  (' PTPN11%0'  ' SMAD2%0')  (' PTPN11%0'  ' MDM2_g%0')  (' PTPN11%0'  ' BAX%0')  (' PTPN11%0'  ' PRKACA%0')  (' PTPN11%0'  ' TGFB1%0')  (' PTPN11%0'  ' MAP3K8%0')  (' PTPN11%0'  ' TSC_f%0')  (' PTPN11%0'  ' SMAD4%0')  (' PTPN11%0'  ' BAD%0')  (' PTPN11%0'  ' MAP3K5%0')  (' PTPN11%0'  ' AKT1S1%0')  (' PTPN11%0'  ' SKI%0')  (' PTPN11%0'  ' SMAD3%0')  (' PTPN11%0'  ' MAPKAPK2%0')  (' PTPN11%0'  ' DUSP1_g%0')  (' PTPN11%0'  ' MSK_f%0')  (' PTPN11%0'  ' GRAP2%0')  (' PTPN11%0'  ' TAB_f%0')  (' PTPN11%0'  ' ATF2%0')  (' PTPN11%0'  ' SMAD5%0')  (' PTPN11%0'  ' SMAD1%0')  (' PTPN11%0'  ' FOS%0')  (' PTPN11%0'  ' JUN%0')  (' PTPN11%0'  ' MAP3K7%0')  (' PTPN11%0'  ' NLK%0')  (' PTPN11%0'  ' SMAD7_g%0')  (' PTPN11%0'  ' SMAD6_g%0')  (' PTPN11%0'  ' AP1_c%0')  (' PTPN11%0'  ' ACVR1%0')  (' PTPN11%0'  ' PTPN6%0')  (' PTPN11%0'  ' CDC42%0')  (' PTPN11%0'  ' GRB2%0')  (' PTPN11%0'  ' TGFBR1%0')  (' PTPN11%0'  ' SMURF1%0')  (' PTPN11%0'  ' SMURF2%0')  (' PTPN11%0'  ' RHOA%0')  (' PTPN11%0'  ' BMPR2%0')  (' PTPN11%0'  ' PARD6A%0')  (' PTPN11%0'  ' DAAM1%0')  (' PTPN11%0'  ' SFRP1_g%0')  (' PTPN11%0'  ' PPM1A%0')  (' PTPN11%0'  ' CFL_f%0')  (' PTPN11%0'  ' PAK1%0')  (' PTPN11%0'  ' MAP3K11%0')  (' PTPN11%0'  ' MAP3K4%0')  (' PTPN11%0'  ' LIMK1%0')  (' PTPN11%0'  ' ROCK1%0')  (' PTPN11%0'  ' ITCH%0')  (' PTPN11%0'  ' ARHGAP24%0')  (' PTPN11%0'  ' TIAM1%0')  (' PTPN11%0'  ' RND3%0')  (' PTPN11%0'  ' MAPK8IP3%0')  (' PTPN11%0'  ' MXD1%0')  (' PTPN11%0'  ' PIP3%0')  (' KRAS%0'  ' SRC%0')  (' KRAS%0'  ' CSK%0')  (' KRAS%0'  ' CHUK%0')  (' KRAS%0'  ' RAC_f%0')  (' KRAS%0'  ' DUSP1%0')  (' KRAS%0'  ' TGFBR2%0')  (' KRAS%0'  ' ILR_f%0')  (' KRAS%0'  ' SYK%0')  (' KRAS%0'  ' IRAK1%0')  (' KRAS%0'  ' SHC1%0')  (' KRAS%0'  ' JAK_f%0')  (' KRAS%0'  ' CBPp300_c%0')  (' KRAS%0'  ' SKP2%0')  (' KRAS%0'  ' TP53%0')  (' KRAS%0'  ' SMAD7%0')  (' KRAS%0'  ' SMAD6%0')  (' KRAS%0'  ' DKK_f%0')  (' KRAS%0'  ' FOXO_f%0')  (' KRAS%0'  ' TCF7_f%0')  (' KRAS%0'  ' DKK_g%0')  (' KRAS%0'  ' MYC%0')  (' KRAS%0'  ' CCND1%0')  (' KRAS%0'  ' EGR1%0')  (' KRAS%0'  ' MMP_f%0')  (' KRAS%0'  ' PTEN_g%0')  (' KRAS%0'  ' RTPK_f%0')  (' KRAS%0'  ' CTNNB1%0')  (' KRAS%0'  'LEF1%0')  (' KRAS%0'  'SFRP1%0')  (' KRAS%0'  'FZD_f%0')  (' KRAS%0'  ' CASP8%0')  (' KRAS%0'  ' REL_f%0')  (' KRAS%0'  ' NFKB_f%0')  (' KRAS%0'  ' DVL_f%0')  (' KRAS%0'  ' LRP_f%0')  (' KRAS%0'  ' BTRC%0')  (' KRAS%0'  ' CK1_f%0')  (' KRAS%0'  ' AXIN1%0')  (' KRAS%0'  ' mTORC2_c%0')  (' KRAS%0'  ' PDPK1%0')  (' KRAS%0'  ' MEK_f%0')  (' KRAS%0'  ' CYCS%0')  (' KRAS%0'  ' CASP9%0')  (' KRAS%0'  ' GSK3_f%0')  (' KRAS%0'  ' IRS1%0')  (' KRAS%0'  ' MDM2%0')  (' KRAS%0'  ' AKT_f%0')  (' KRAS%0'  ' BCL2%0')  (' KRAS%0'  ' RAF_f%0')  (' KRAS%0'  ' mTORC1_c%0')  (' KRAS%0'  ' RHEB%0')  (' KRAS%0'  ' RTPK_g%0')  (' KRAS%0'  ' PTEN%0')  (' KRAS%0'  ' CASP3%0')  (' KRAS%0'  ' PIK3CA%0')  (' KRAS%0'  ' CREBBP%0')  (' KRAS%0'  ' PTPN11%0')  (' KRAS%0'  ' MAP2K4%0')  (' KRAS%0'  ' MAP2K7%0')  (' KRAS%0'  ' MAPK14%0')  (' KRAS%0'  ' JNK_f%0')  (' KRAS%0'  ' MAP2K3%0')  (' KRAS%0'  ' ERK_f%0')  (' KRAS%0'  ' LIF%0')  (' KRAS%0'  ' PPP1CA%0')  (' KRAS%0'  ' GAB_f%0')  (' KRAS%0'  ' SOS1%0')  (' KRAS%0'  ' PRKCA%0')  (' KRAS%0'  ' VAV1%0')  (' KRAS%0'  ' PLCG1%0')  (' KRAS%0'  ' PRKCD%0')  (' KRAS%0'  ' RSK_f%0')  (' KRAS%0'  ' S6K_f%0')  (' KRAS%0'  ' PLK1%0')  (' KRAS%0'  ' ILK%0')  (' KRAS%0'  ' SOCS1%0')  (' KRAS%0'  ' DUSP6%0')  (' KRAS%0'  ' STAT3%0')  (' KRAS%0'  ' LIMK2%0')  (' KRAS%0'  ' EP300%0')  (' KRAS%0'  ' STAT1%0')  (' KRAS%0'  ' IKBKB%0')  (' KRAS%0'  ' SRF%0')  (' KRAS%0'  ' PIAS1%0')  (' KRAS%0'  ' TRAF6%0')  (' KRAS%0'  ' SOCS1_g%0')  (' KRAS%0'  ' ISGF3_c%0')  (' KRAS%0'  ' STAT2%0')  (' KRAS%0'  ' CFLAR%0')  (' KRAS%0'  ' SMAD2%0')  (' KRAS%0'  ' MDM2_g%0')  (' KRAS%0'  ' BAX%0')  (' KRAS%0'  ' PRKACA%0')  (' KRAS%0'  ' TGFB1%0')  (' KRAS%0'  ' MAP3K8%0')  (' KRAS%0'  ' TSC_f%0')  (' KRAS%0'  ' SMAD4%0')  (' KRAS%0'  ' BAD%0')  (' KRAS%0'  ' MAP3K5%0')  (' KRAS%0'  ' AKT1S1%0')  (' KRAS%0'  ' SKI%0')  (' KRAS%0'  ' SMAD3%0')  (' KRAS%0'  ' MAPKAPK2%0')  (' KRAS%0'  ' DUSP1_g%0')  (' KRAS%0'  ' MSK_f%0')  (' KRAS%0'  ' GRAP2%0')  (' KRAS%0'  ' TAB_f%0')  (' KRAS%0'  ' ATF2%0')  (' KRAS%0'  ' SMAD5%0')  (' KRAS%0'  ' SMAD1%0')  (' KRAS%0'  ' FOS%0')  (' KRAS%0'  ' JUN%0')  (' KRAS%0'  ' MAP3K7%0')  (' KRAS%0'  ' NLK%0')  (' KRAS%0'  ' SMAD7_g%0')  (' KRAS%0'  ' SMAD6_g%0')  (' KRAS%0'  ' AP1_c%0')  (' KRAS%0'  ' ACVR1%0')  (' KRAS%0'  ' PTPN6%0')  (' KRAS%0'  ' CDC42%0')  (' KRAS%0'  ' GRB2%0')  (' KRAS%0'  ' TGFBR1%0')  (' KRAS%0'  ' SMURF1%0')  (' KRAS%0'  ' SMURF2%0')  (' KRAS%0'  ' RHOA%0')  (' KRAS%0'  ' BMPR2%0')  (' KRAS%0'  ' PARD6A%0')  (' KRAS%0'  ' DAAM1%0')  (' KRAS%0'  ' SFRP1_g%0')  (' KRAS%0'  ' PPM1A%0')  (' KRAS%0'  ' CFL_f%0')  (' KRAS%0'  ' PAK1%0')  (' KRAS%0'  ' MAP3K11%0')  (' KRAS%0'  ' MAP3K4%0')  (' KRAS%0'  ' LIMK1%0')  (' KRAS%0'  ' ROCK1%0')  (' KRAS%0'  ' ITCH%0')  (' KRAS%0'  ' ARHGAP24%0')  (' KRAS%0'  ' TIAM1%0')  (' KRAS%0'  ' RND3%0')  (' KRAS%0'  ' MAPK8IP3%0')  (' KRAS%0'  ' MXD1%0')  (' KRAS%0'  ' PIP3%0')  (' MAP2K4%0'  ' SRC%0')  (' MAP2K4%0'  ' CSK%0')  (' MAP2K4%0'  ' CHUK%0')  (' MAP2K4%0'  ' RAC_f%0')  (' MAP2K4%0'  ' DUSP1%0')  (' MAP2K4%0'  ' TGFBR2%0')  (' MAP2K4%0'  ' ILR_f%0')  (' MAP2K4%0'  ' SYK%0')  (' MAP2K4%0'  ' IRAK1%0')  (' MAP2K4%0'  ' SHC1%0')  (' MAP2K4%0'  ' JAK_f%0')  (' MAP2K4%0'  ' CBPp300_c%0')  (' MAP2K4%0'  ' SKP2%0')  (' MAP2K4%0'  ' TP53%0')  (' MAP2K4%0'  ' SMAD7%0')  (' MAP2K4%0'  ' SMAD6%0')  (' MAP2K4%0'  ' DKK_f%0')  (' MAP2K4%0'  ' FOXO_f%0')  (' MAP2K4%0'  ' TCF7_f%0')  (' MAP2K4%0'  ' DKK_g%0')  (' MAP2K4%0'  ' MYC%0')  (' MAP2K4%0'  ' CCND1%0')  (' MAP2K4%0'  ' EGR1%0')  (' MAP2K4%0'  ' MMP_f%0')  (' MAP2K4%0'  ' PTEN_g%0')  (' MAP2K4%0'  ' RTPK_f%0')  (' MAP2K4%0'  ' CTNNB1%0')  (' MAP2K4%0'  'LEF1%0')  (' MAP2K4%0'  'SFRP1%0')  (' MAP2K4%0'  'FZD_f%0')  (' MAP2K4%0'  ' CASP8%0')  (' MAP2K4%0'  ' REL_f%0')  (' MAP2K4%0'  ' NFKB_f%0')  (' MAP2K4%0'  ' DVL_f%0')  (' MAP2K4%0'  ' LRP_f%0')  (' MAP2K4%0'  ' BTRC%0')  (' MAP2K4%0'  ' CK1_f%0')  (' MAP2K4%0'  ' AXIN1%0')  (' MAP2K4%0'  ' mTORC2_c%0')  (' MAP2K4%0'  ' PDPK1%0')  (' MAP2K4%0'  ' MEK_f%0')  (' MAP2K4%0'  ' CYCS%0')  (' MAP2K4%0'  ' CASP9%0')  (' MAP2K4%0'  ' GSK3_f%0')  (' MAP2K4%0'  ' IRS1%0')  (' MAP2K4%0'  ' MDM2%0')  (' MAP2K4%0'  ' AKT_f%0')  (' MAP2K4%0'  ' BCL2%0')  (' MAP2K4%0'  ' RAF_f%0')  (' MAP2K4%0'  ' mTORC1_c%0')  (' MAP2K4%0'  ' RHEB%0')  (' MAP2K4%0'  ' RTPK_g%0')  (' MAP2K4%0'  ' PTEN%0')  (' MAP2K4%0'  ' CASP3%0')  (' MAP2K4%0'  ' PIK3CA%0')  (' MAP2K4%0'  ' CREBBP%0')  (' MAP2K4%0'  ' PTPN11%0')  (' MAP2K4%0'  ' KRAS%0')  (' MAP2K4%0'  ' MAP2K7%0')  (' MAP2K4%0'  ' MAPK14%0')  (' MAP2K4%0'  ' JNK_f%0')  (' MAP2K4%0'  ' MAP2K3%0')  (' MAP2K4%0'  ' ERK_f%0')  (' MAP2K4%0'  ' LIF%0')  (' MAP2K4%0'  ' PPP1CA%0')  (' MAP2K4%0'  ' GAB_f%0')  (' MAP2K4%0'  ' SOS1%0')  (' MAP2K4%0'  ' PRKCA%0')  (' MAP2K4%0'  ' VAV1%0')  (' MAP2K4%0'  ' PLCG1%0')  (' MAP2K4%0'  ' PRKCD%0')  (' MAP2K4%0'  ' RSK_f%0')  (' MAP2K4%0'  ' S6K_f%0')  (' MAP2K4%0'  ' PLK1%0')  (' MAP2K4%0'  ' ILK%0')  (' MAP2K4%0'  ' SOCS1%0')  (' MAP2K4%0'  ' DUSP6%0')  (' MAP2K4%0'  ' STAT3%0')  (' MAP2K4%0'  ' LIMK2%0')  (' MAP2K4%0'  ' EP300%0')  (' MAP2K4%0'  ' STAT1%0')  (' MAP2K4%0'  ' IKBKB%0')  (' MAP2K4%0'  ' SRF%0')  (' MAP2K4%0'  ' PIAS1%0')  (' MAP2K4%0'  ' TRAF6%0')  (' MAP2K4%0'  ' SOCS1_g%0')  (' MAP2K4%0'  ' ISGF3_c%0')  (' MAP2K4%0'  ' STAT2%0')  (' MAP2K4%0'  ' CFLAR%0')  (' MAP2K4%0'  ' SMAD2%0')  (' MAP2K4%0'  ' MDM2_g%0')  (' MAP2K4%0'  ' BAX%0')  (' MAP2K4%0'  ' PRKACA%0')  (' MAP2K4%0'  ' TGFB1%0')  (' MAP2K4%0'  ' MAP3K8%0')  (' MAP2K4%0'  ' TSC_f%0')  (' MAP2K4%0'  ' SMAD4%0')  (' MAP2K4%0'  ' BAD%0')  (' MAP2K4%0'  ' MAP3K5%0')  (' MAP2K4%0'  ' AKT1S1%0')  (' MAP2K4%0'  ' SKI%0')  (' MAP2K4%0'  ' SMAD3%0')  (' MAP2K4%0'  ' MAPKAPK2%0')  (' MAP2K4%0'  ' DUSP1_g%0')  (' MAP2K4%0'  ' MSK_f%0')  (' MAP2K4%0'  ' GRAP2%0')  (' MAP2K4%0'  ' TAB_f%0')  (' MAP2K4%0'  ' ATF2%0')  (' MAP2K4%0'  ' SMAD5%0')  (' MAP2K4%0'  ' SMAD1%0')  (' MAP2K4%0'  ' FOS%0')  (' MAP2K4%0'  ' JUN%0')  (' MAP2K4%0'  ' MAP3K7%0')  (' MAP2K4%0'  ' NLK%0')  (' MAP2K4%0'  ' SMAD7_g%0')  (' MAP2K4%0'  ' SMAD6_g%0')  (' MAP2K4%0'  ' AP1_c%0')  (' MAP2K4%0'  ' ACVR1%0')  (' MAP2K4%0'  ' PTPN6%0')  (' MAP2K4%0'  ' CDC42%0')  (' MAP2K4%0'  ' GRB2%0')  (' MAP2K4%0'  ' TGFBR1%0')  (' MAP2K4%0'  ' SMURF1%0')  (' MAP2K4%0'  ' SMURF2%0')  (' MAP2K4%0'  ' RHOA%0')  (' MAP2K4%0'  ' BMPR2%0')  (' MAP2K4%0'  ' PARD6A%0')  (' MAP2K4%0'  ' DAAM1%0')  (' MAP2K4%0'  ' SFRP1_g%0')  (' MAP2K4%0'  ' PPM1A%0')  (' MAP2K4%0'  ' CFL_f%0')  (' MAP2K4%0'  ' PAK1%0')  (' MAP2K4%0'  ' MAP3K11%0')  (' MAP2K4%0'  ' MAP3K4%0')  (' MAP2K4%0'  ' LIMK1%0')  (' MAP2K4%0'  ' ROCK1%0')  (' MAP2K4%0'  ' ITCH%0')  (' MAP2K4%0'  ' ARHGAP24%0')  (' MAP2K4%0'  ' TIAM1%0')  (' MAP2K4%0'  ' RND3%0')  (' MAP2K4%0'  ' MAPK8IP3%0')  (' MAP2K4%0'  ' MXD1%0')  (' MAP2K4%0'  ' PIP3%0')  (' MAP2K7%0'  ' SRC%0')  (' MAP2K7%0'  ' CSK%0')  (' MAP2K7%0'  ' CHUK%0')  (' MAP2K7%0'  ' RAC_f%0')  (' MAP2K7%0'  ' DUSP1%0')  (' MAP2K7%0'  ' TGFBR2%0')  (' MAP2K7%0'  ' ILR_f%0')  (' MAP2K7%0'  ' SYK%0')  (' MAP2K7%0'  ' IRAK1%0')  (' MAP2K7%0'  ' SHC1%0')  (' MAP2K7%0'  ' JAK_f%0')  (' MAP2K7%0'  ' CBPp300_c%0')  (' MAP2K7%0'  ' SKP2%0')  (' MAP2K7%0'  ' TP53%0')  (' MAP2K7%0'  ' SMAD7%0')  (' MAP2K7%0'  ' SMAD6%0')  (' MAP2K7%0'  ' DKK_f%0')  (' MAP2K7%0'  ' FOXO_f%0')  (' MAP2K7%0'  ' TCF7_f%0')  (' MAP2K7%0'  ' DKK_g%0')  (' MAP2K7%0'  ' MYC%0')  (' MAP2K7%0'  ' CCND1%0')  (' MAP2K7%0'  ' EGR1%0')  (' MAP2K7%0'  ' MMP_f%0')  (' MAP2K7%0'  ' PTEN_g%0')  (' MAP2K7%0'  ' RTPK_f%0')  (' MAP2K7%0'  ' CTNNB1%0')  (' MAP2K7%0'  'LEF1%0')  (' MAP2K7%0'  'SFRP1%0')  (' MAP2K7%0'  'FZD_f%0')  (' MAP2K7%0'  ' CASP8%0')  (' MAP2K7%0'  ' REL_f%0')  (' MAP2K7%0'  ' NFKB_f%0')  (' MAP2K7%0'  ' DVL_f%0')  (' MAP2K7%0'  ' LRP_f%0')  (' MAP2K7%0'  ' BTRC%0')  (' MAP2K7%0'  ' CK1_f%0')  (' MAP2K7%0'  ' AXIN1%0')  (' MAP2K7%0'  ' mTORC2_c%0')  (' MAP2K7%0'  ' PDPK1%0')  (' MAP2K7%0'  ' MEK_f%0')  (' MAP2K7%0'  ' CYCS%0')  (' MAP2K7%0'  ' CASP9%0')  (' MAP2K7%0'  ' GSK3_f%0')  (' MAP2K7%0'  ' IRS1%0')  (' MAP2K7%0'  ' MDM2%0')  (' MAP2K7%0'  ' AKT_f%0')  (' MAP2K7%0'  ' BCL2%0')  (' MAP2K7%0'  ' RAF_f%0')  (' MAP2K7%0'  ' mTORC1_c%0')  (' MAP2K7%0'  ' RHEB%0')  (' MAP2K7%0'  ' RTPK_g%0')  (' MAP2K7%0'  ' PTEN%0')  (' MAP2K7%0'  ' CASP3%0')  (' MAP2K7%0'  ' PIK3CA%0')  (' MAP2K7%0'  ' CREBBP%0')  (' MAP2K7%0'  ' PTPN11%0')  (' MAP2K7%0'  ' KRAS%0')  (' MAP2K7%0'  ' MAP2K4%0')  (' MAP2K7%0'  ' MAPK14%0')  (' MAP2K7%0'  ' JNK_f%0')  (' MAP2K7%0'  ' MAP2K3%0')  (' MAP2K7%0'  ' ERK_f%0')  (' MAP2K7%0'  ' LIF%0')  (' MAP2K7%0'  ' PPP1CA%0')  (' MAP2K7%0'  ' GAB_f%0')  (' MAP2K7%0'  ' SOS1%0')  (' MAP2K7%0'  ' PRKCA%0')  (' MAP2K7%0'  ' VAV1%0')  (' MAP2K7%0'  ' PLCG1%0')  (' MAP2K7%0'  ' PRKCD%0')  (' MAP2K7%0'  ' RSK_f%0')  (' MAP2K7%0'  ' S6K_f%0')  (' MAP2K7%0'  ' PLK1%0')  (' MAP2K7%0'  ' ILK%0')  (' MAP2K7%0'  ' SOCS1%0')  (' MAP2K7%0'  ' DUSP6%0')  (' MAP2K7%0'  ' STAT3%0')  (' MAP2K7%0'  ' LIMK2%0')  (' MAP2K7%0'  ' EP300%0')  (' MAP2K7%0'  ' STAT1%0')  (' MAP2K7%0'  ' IKBKB%0')  (' MAP2K7%0'  ' SRF%0')  (' MAP2K7%0'  ' PIAS1%0')  (' MAP2K7%0'  ' TRAF6%0')  (' MAP2K7%0'  ' SOCS1_g%0')  (' MAP2K7%0'  ' ISGF3_c%0')  (' MAP2K7%0'  ' STAT2%0')  (' MAP2K7%0'  ' CFLAR%0')  (' MAP2K7%0'  ' SMAD2%0')  (' MAP2K7%0'  ' MDM2_g%0')  (' MAP2K7%0'  ' BAX%0')  (' MAP2K7%0'  ' PRKACA%0')  (' MAP2K7%0'  ' TGFB1%0')  (' MAP2K7%0'  ' MAP3K8%0')  (' MAP2K7%0'  ' TSC_f%0')  (' MAP2K7%0'  ' SMAD4%0')  (' MAP2K7%0'  ' BAD%0')  (' MAP2K7%0'  ' MAP3K5%0')  (' MAP2K7%0'  ' AKT1S1%0')  (' MAP2K7%0'  ' SKI%0')  (' MAP2K7%0'  ' SMAD3%0')  (' MAP2K7%0'  ' MAPKAPK2%0')  (' MAP2K7%0'  ' DUSP1_g%0')  (' MAP2K7%0'  ' MSK_f%0')  (' MAP2K7%0'  ' GRAP2%0')  (' MAP2K7%0'  ' TAB_f%0')  (' MAP2K7%0'  ' ATF2%0')  (' MAP2K7%0'  ' SMAD5%0')  (' MAP2K7%0'  ' SMAD1%0')  (' MAP2K7%0'  ' FOS%0')  (' MAP2K7%0'  ' JUN%0')  (' MAP2K7%0'  ' MAP3K7%0')  (' MAP2K7%0'  ' NLK%0')  (' MAP2K7%0'  ' SMAD7_g%0')  (' MAP2K7%0'  ' SMAD6_g%0')  (' MAP2K7%0'  ' AP1_c%0')  (' MAP2K7%0'  ' ACVR1%0')  (' MAP2K7%0'  ' PTPN6%0')  (' MAP2K7%0'  ' CDC42%0')  (' MAP2K7%0'  ' GRB2%0')  (' MAP2K7%0'  ' TGFBR1%0')  (' MAP2K7%0'  ' SMURF1%0')  (' MAP2K7%0'  ' SMURF2%0')  (' MAP2K7%0'  ' RHOA%0')  (' MAP2K7%0'  ' BMPR2%0')  (' MAP2K7%0'  ' PARD6A%0')  (' MAP2K7%0'  ' DAAM1%0')  (' MAP2K7%0'  ' SFRP1_g%0')  (' MAP2K7%0'  ' PPM1A%0')  (' MAP2K7%0'  ' CFL_f%0')  (' MAP2K7%0'  ' PAK1%0')  (' MAP2K7%0'  ' MAP3K11%0')  (' MAP2K7%0'  ' MAP3K4%0')  (' MAP2K7%0'  ' LIMK1%0')  (' MAP2K7%0'  ' ROCK1%0')  (' MAP2K7%0'  ' ITCH%0')  (' MAP2K7%0'  ' ARHGAP24%0')  (' MAP2K7%0'  ' TIAM1%0')  (' MAP2K7%0'  ' RND3%0')  (' MAP2K7%0'  ' MAPK8IP3%0')  (' MAP2K7%0'  ' MXD1%0')  (' MAP2K7%0'  ' PIP3%0')  (' MAPK14%0'  ' SRC%0')  (' MAPK14%0'  ' CSK%0')  (' MAPK14%0'  ' CHUK%0')  (' MAPK14%0'  ' RAC_f%0')  (' MAPK14%0'  ' DUSP1%0')  (' MAPK14%0'  ' TGFBR2%0')  (' MAPK14%0'  ' ILR_f%0')  (' MAPK14%0'  ' SYK%0')  (' MAPK14%0'  ' IRAK1%0')  (' MAPK14%0'  ' SHC1%0')  (' MAPK14%0'  ' JAK_f%0')  (' MAPK14%0'  ' CBPp300_c%0')  (' MAPK14%0'  ' SKP2%0')  (' MAPK14%0'  ' TP53%0')  (' MAPK14%0'  ' SMAD7%0')  (' MAPK14%0'  ' SMAD6%0')  (' MAPK14%0'  ' DKK_f%0')  (' MAPK14%0'  ' FOXO_f%0')  (' MAPK14%0'  ' TCF7_f%0')  (' MAPK14%0'  ' DKK_g%0')  (' MAPK14%0'  ' MYC%0')  (' MAPK14%0'  ' CCND1%0')  (' MAPK14%0'  ' EGR1%0')  (' MAPK14%0'  ' MMP_f%0')  (' MAPK14%0'  ' PTEN_g%0')  (' MAPK14%0'  ' RTPK_f%0')  (' MAPK14%0'  ' CTNNB1%0')  (' MAPK14%0'  'LEF1%0')  (' MAPK14%0'  'SFRP1%0')  (' MAPK14%0'  'FZD_f%0')  (' MAPK14%0'  ' CASP8%0')  (' MAPK14%0'  ' REL_f%0')  (' MAPK14%0'  ' NFKB_f%0')  (' MAPK14%0'  ' DVL_f%0')  (' MAPK14%0'  ' LRP_f%0')  (' MAPK14%0'  ' BTRC%0')  (' MAPK14%0'  ' CK1_f%0')  (' MAPK14%0'  ' AXIN1%0')  (' MAPK14%0'  ' mTORC2_c%0')  (' MAPK14%0'  ' PDPK1%0')  (' MAPK14%0'  ' MEK_f%0')  (' MAPK14%0'  ' CYCS%0')  (' MAPK14%0'  ' CASP9%0')  (' MAPK14%0'  ' GSK3_f%0')  (' MAPK14%0'  ' IRS1%0')  (' MAPK14%0'  ' MDM2%0')  (' MAPK14%0'  ' AKT_f%0')  (' MAPK14%0'  ' BCL2%0')  (' MAPK14%0'  ' RAF_f%0')  (' MAPK14%0'  ' mTORC1_c%0')  (' MAPK14%0'  ' RHEB%0')  (' MAPK14%0'  ' RTPK_g%0')  (' MAPK14%0'  ' PTEN%0')  (' MAPK14%0'  ' CASP3%0')  (' MAPK14%0'  ' PIK3CA%0')  (' MAPK14%0'  ' CREBBP%0')  (' MAPK14%0'  ' PTPN11%0')  (' MAPK14%0'  ' KRAS%0')  (' MAPK14%0'  ' MAP2K4%0')  (' MAPK14%0'  ' MAP2K7%0')  (' MAPK14%0'  ' JNK_f%0')  (' MAPK14%0'  ' MAP2K3%0')  (' MAPK14%0'  ' ERK_f%0')  (' MAPK14%0'  ' LIF%0')  (' MAPK14%0'  ' PPP1CA%0')  (' MAPK14%0'  ' GAB_f%0')  (' MAPK14%0'  ' SOS1%0')  (' MAPK14%0'  ' PRKCA%0')  (' MAPK14%0'  ' VAV1%0')  (' MAPK14%0'  ' PLCG1%0')  (' MAPK14%0'  ' PRKCD%0')  (' MAPK14%0'  ' RSK_f%0')  (' MAPK14%0'  ' S6K_f%0')  (' MAPK14%0'  ' PLK1%0')  (' MAPK14%0'  ' ILK%0')  (' MAPK14%0'  ' SOCS1%0')  (' MAPK14%0'  ' DUSP6%0')  (' MAPK14%0'  ' STAT3%0')  (' MAPK14%0'  ' LIMK2%0')  (' MAPK14%0'  ' EP300%0')  (' MAPK14%0'  ' STAT1%0')  (' MAPK14%0'  ' IKBKB%0')  (' MAPK14%0'  ' SRF%0')  (' MAPK14%0'  ' PIAS1%0')  (' MAPK14%0'  ' TRAF6%0')  (' MAPK14%0'  ' SOCS1_g%0')  (' MAPK14%0'  ' ISGF3_c%0')  (' MAPK14%0'  ' STAT2%0')  (' MAPK14%0'  ' CFLAR%0')  (' MAPK14%0'  ' SMAD2%0')  (' MAPK14%0'  ' MDM2_g%0')  (' MAPK14%0'  ' BAX%0')  (' MAPK14%0'  ' PRKACA%0')  (' MAPK14%0'  ' TGFB1%0')  (' MAPK14%0'  ' MAP3K8%0')  (' MAPK14%0'  ' TSC_f%0')  (' MAPK14%0'  ' SMAD4%0')  (' MAPK14%0'  ' BAD%0')  (' MAPK14%0'  ' MAP3K5%0')  (' MAPK14%0'  ' AKT1S1%0')  (' MAPK14%0'  ' SKI%0')  (' MAPK14%0'  ' SMAD3%0')  (' MAPK14%0'  ' MAPKAPK2%0')  (' MAPK14%0'  ' DUSP1_g%0')  (' MAPK14%0'  ' MSK_f%0')  (' MAPK14%0'  ' GRAP2%0')  (' MAPK14%0'  ' TAB_f%0')  (' MAPK14%0'  ' ATF2%0')  (' MAPK14%0'  ' SMAD5%0')  (' MAPK14%0'  ' SMAD1%0')  (' MAPK14%0'  ' FOS%0')  (' MAPK14%0'  ' JUN%0')  (' MAPK14%0'  ' MAP3K7%0')  (' MAPK14%0'  ' NLK%0')  (' MAPK14%0'  ' SMAD7_g%0')  (' MAPK14%0'  ' SMAD6_g%0')  (' MAPK14%0'  ' AP1_c%0')  (' MAPK14%0'  ' ACVR1%0')  (' MAPK14%0'  ' PTPN6%0')  (' MAPK14%0'  ' CDC42%0')  (' MAPK14%0'  ' GRB2%0')  (' MAPK14%0'  ' TGFBR1%0')  (' MAPK14%0'  ' SMURF1%0')  (' MAPK14%0'  ' SMURF2%0')  (' MAPK14%0'  ' RHOA%0')  (' MAPK14%0'  ' BMPR2%0')  (' MAPK14%0'  ' PARD6A%0')  (' MAPK14%0'  ' DAAM1%0')  (' MAPK14%0'  ' SFRP1_g%0')  (' MAPK14%0'  ' PPM1A%0')  (' MAPK14%0'  ' CFL_f%0')  (' MAPK14%0'  ' PAK1%0')  (' MAPK14%0'  ' MAP3K11%0')  (' MAPK14%0'  ' MAP3K4%0')  (' MAPK14%0'  ' LIMK1%0')  (' MAPK14%0'  ' ROCK1%0')  (' MAPK14%0'  ' ITCH%0')  (' MAPK14%0'  ' ARHGAP24%0')  (' MAPK14%0'  ' TIAM1%0')  (' MAPK14%0'  ' RND3%0')  (' MAPK14%0'  ' MAPK8IP3%0')  (' MAPK14%0'  ' MXD1%0')  (' MAPK14%0'  ' PIP3%0')  (' JNK_f%0'  ' SRC%0')  (' JNK_f%0'  ' CSK%0')  (' JNK_f%0'  ' CHUK%0')  (' JNK_f%0'  ' RAC_f%0')  (' JNK_f%0'  ' DUSP1%0')  (' JNK_f%0'  ' TGFBR2%0')  (' JNK_f%0'  ' ILR_f%0')  (' JNK_f%0'  ' SYK%0')  (' JNK_f%0'  ' IRAK1%0')  (' JNK_f%0'  ' SHC1%0')  (' JNK_f%0'  ' JAK_f%0')  (' JNK_f%0'  ' CBPp300_c%0')  (' JNK_f%0'  ' SKP2%0')  (' JNK_f%0'  ' TP53%0')  (' JNK_f%0'  ' SMAD7%0')  (' JNK_f%0'  ' SMAD6%0')  (' JNK_f%0'  ' DKK_f%0')  (' JNK_f%0'  ' FOXO_f%0')  (' JNK_f%0'  ' TCF7_f%0')  (' JNK_f%0'  ' DKK_g%0')  (' JNK_f%0'  ' MYC%0')  (' JNK_f%0'  ' CCND1%0')  (' JNK_f%0'  ' EGR1%0')  (' JNK_f%0'  ' MMP_f%0')  (' JNK_f%0'  ' PTEN_g%0')  (' JNK_f%0'  ' RTPK_f%0')  (' JNK_f%0'  ' CTNNB1%0')  (' JNK_f%0'  'LEF1%0')  (' JNK_f%0'  'SFRP1%0')  (' JNK_f%0'  'FZD_f%0')  (' JNK_f%0'  ' CASP8%0')  (' JNK_f%0'  ' REL_f%0')  (' JNK_f%0'  ' NFKB_f%0')  (' JNK_f%0'  ' DVL_f%0')  (' JNK_f%0'  ' LRP_f%0')  (' JNK_f%0'  ' BTRC%0')  (' JNK_f%0'  ' CK1_f%0')  (' JNK_f%0'  ' AXIN1%0')  (' JNK_f%0'  ' mTORC2_c%0')  (' JNK_f%0'  ' PDPK1%0')  (' JNK_f%0'  ' MEK_f%0')  (' JNK_f%0'  ' CYCS%0')  (' JNK_f%0'  ' CASP9%0')  (' JNK_f%0'  ' GSK3_f%0')  (' JNK_f%0'  ' IRS1%0')  (' JNK_f%0'  ' MDM2%0')  (' JNK_f%0'  ' AKT_f%0')  (' JNK_f%0'  ' BCL2%0')  (' JNK_f%0'  ' RAF_f%0')  (' JNK_f%0'  ' mTORC1_c%0')  (' JNK_f%0'  ' RHEB%0')  (' JNK_f%0'  ' RTPK_g%0')  (' JNK_f%0'  ' PTEN%0')  (' JNK_f%0'  ' CASP3%0')  (' JNK_f%0'  ' PIK3CA%0')  (' JNK_f%0'  ' CREBBP%0')  (' JNK_f%0'  ' PTPN11%0')  (' JNK_f%0'  ' KRAS%0')  (' JNK_f%0'  ' MAP2K4%0')  (' JNK_f%0'  ' MAP2K7%0')  (' JNK_f%0'  ' MAPK14%0')  (' JNK_f%0'  ' MAP2K3%0')  (' JNK_f%0'  ' ERK_f%0')  (' JNK_f%0'  ' LIF%0')  (' JNK_f%0'  ' PPP1CA%0')  (' JNK_f%0'  ' GAB_f%0')  (' JNK_f%0'  ' SOS1%0')  (' JNK_f%0'  ' PRKCA%0')  (' JNK_f%0'  ' VAV1%0')  (' JNK_f%0'  ' PLCG1%0')  (' JNK_f%0'  ' PRKCD%0')  (' JNK_f%0'  ' RSK_f%0')  (' JNK_f%0'  ' S6K_f%0')  (' JNK_f%0'  ' PLK1%0')  (' JNK_f%0'  ' ILK%0')  (' JNK_f%0'  ' SOCS1%0')  (' JNK_f%0'  ' DUSP6%0')  (' JNK_f%0'  ' STAT3%0')  (' JNK_f%0'  ' LIMK2%0')  (' JNK_f%0'  ' EP300%0')  (' JNK_f%0'  ' STAT1%0')  (' JNK_f%0'  ' IKBKB%0')  (' JNK_f%0'  ' SRF%0')  (' JNK_f%0'  ' PIAS1%0')  (' JNK_f%0'  ' TRAF6%0')  (' JNK_f%0'  ' SOCS1_g%0')  (' JNK_f%0'  ' ISGF3_c%0')  (' JNK_f%0'  ' STAT2%0')  (' JNK_f%0'  ' CFLAR%0')  (' JNK_f%0'  ' SMAD2%0')  (' JNK_f%0'  ' MDM2_g%0')  (' JNK_f%0'  ' BAX%0')  (' JNK_f%0'  ' PRKACA%0')  (' JNK_f%0'  ' TGFB1%0')  (' JNK_f%0'  ' MAP3K8%0')  (' JNK_f%0'  ' TSC_f%0')  (' JNK_f%0'  ' SMAD4%0')  (' JNK_f%0'  ' BAD%0')  (' JNK_f%0'  ' MAP3K5%0')  (' JNK_f%0'  ' AKT1S1%0')  (' JNK_f%0'  ' SKI%0')  (' JNK_f%0'  ' SMAD3%0')  (' JNK_f%0'  ' MAPKAPK2%0')  (' JNK_f%0'  ' DUSP1_g%0')  (' JNK_f%0'  ' MSK_f%0')  (' JNK_f%0'  ' GRAP2%0')  (' JNK_f%0'  ' TAB_f%0')  (' JNK_f%0'  ' ATF2%0')  (' JNK_f%0'  ' SMAD5%0')  (' JNK_f%0'  ' SMAD1%0')  (' JNK_f%0'  ' FOS%0')  (' JNK_f%0'  ' JUN%0')  (' JNK_f%0'  ' MAP3K7%0')  (' JNK_f%0'  ' NLK%0')  (' JNK_f%0'  ' SMAD7_g%0')  (' JNK_f%0'  ' SMAD6_g%0')  (' JNK_f%0'  ' AP1_c%0')  (' JNK_f%0'  ' ACVR1%0')  (' JNK_f%0'  ' PTPN6%0')  (' JNK_f%0'  ' CDC42%0')  (' JNK_f%0'  ' GRB2%0')  (' JNK_f%0'  ' TGFBR1%0')  (' JNK_f%0'  ' SMURF1%0')  (' JNK_f%0'  ' SMURF2%0')  (' JNK_f%0'  ' RHOA%0')  (' JNK_f%0'  ' BMPR2%0')  (' JNK_f%0'  ' PARD6A%0')  (' JNK_f%0'  ' DAAM1%0')  (' JNK_f%0'  ' SFRP1_g%0')  (' JNK_f%0'  ' PPM1A%0')  (' JNK_f%0'  ' CFL_f%0')  (' JNK_f%0'  ' PAK1%0')  (' JNK_f%0'  ' MAP3K11%0')  (' JNK_f%0'  ' MAP3K4%0')  (' JNK_f%0'  ' LIMK1%0')  (' JNK_f%0'  ' ROCK1%0')  (' JNK_f%0'  ' ITCH%0')  (' JNK_f%0'  ' ARHGAP24%0')  (' JNK_f%0'  ' TIAM1%0')  (' JNK_f%0'  ' RND3%0')  (' JNK_f%0'  ' MAPK8IP3%0')  (' JNK_f%0'  ' MXD1%0')  (' JNK_f%0'  ' PIP3%0')  (' MAP2K3%0'  ' SRC%0')  (' MAP2K3%0'  ' CSK%0')  (' MAP2K3%0'  ' CHUK%0')  (' MAP2K3%0'  ' RAC_f%0')  (' MAP2K3%0'  ' DUSP1%0')  (' MAP2K3%0'  ' TGFBR2%0')  (' MAP2K3%0'  ' ILR_f%0')  (' MAP2K3%0'  ' SYK%0')  (' MAP2K3%0'  ' IRAK1%0')  (' MAP2K3%0'  ' SHC1%0')  (' MAP2K3%0'  ' JAK_f%0')  (' MAP2K3%0'  ' CBPp300_c%0')  (' MAP2K3%0'  ' SKP2%0')  (' MAP2K3%0'  ' TP53%0')  (' MAP2K3%0'  ' SMAD7%0')  (' MAP2K3%0'  ' SMAD6%0')  (' MAP2K3%0'  ' DKK_f%0')  (' MAP2K3%0'  ' FOXO_f%0')  (' MAP2K3%0'  ' TCF7_f%0')  (' MAP2K3%0'  ' DKK_g%0')  (' MAP2K3%0'  ' MYC%0')  (' MAP2K3%0'  ' CCND1%0')  (' MAP2K3%0'  ' EGR1%0')  (' MAP2K3%0'  ' MMP_f%0')  (' MAP2K3%0'  ' PTEN_g%0')  (' MAP2K3%0'  ' RTPK_f%0')  (' MAP2K3%0'  ' CTNNB1%0')  (' MAP2K3%0'  'LEF1%0')  (' MAP2K3%0'  'SFRP1%0')  (' MAP2K3%0'  'FZD_f%0')  (' MAP2K3%0'  ' CASP8%0')  (' MAP2K3%0'  ' REL_f%0')  (' MAP2K3%0'  ' NFKB_f%0')  (' MAP2K3%0'  ' DVL_f%0')  (' MAP2K3%0'  ' LRP_f%0')  (' MAP2K3%0'  ' BTRC%0')  (' MAP2K3%0'  ' CK1_f%0')  (' MAP2K3%0'  ' AXIN1%0')  (' MAP2K3%0'  ' mTORC2_c%0')  (' MAP2K3%0'  ' PDPK1%0')  (' MAP2K3%0'  ' MEK_f%0')  (' MAP2K3%0'  ' CYCS%0')  (' MAP2K3%0'  ' CASP9%0')  (' MAP2K3%0'  ' GSK3_f%0')  (' MAP2K3%0'  ' IRS1%0')  (' MAP2K3%0'  ' MDM2%0')  (' MAP2K3%0'  ' AKT_f%0')  (' MAP2K3%0'  ' BCL2%0')  (' MAP2K3%0'  ' RAF_f%0')  (' MAP2K3%0'  ' mTORC1_c%0')  (' MAP2K3%0'  ' RHEB%0')  (' MAP2K3%0'  ' RTPK_g%0')  (' MAP2K3%0'  ' PTEN%0')  (' MAP2K3%0'  ' CASP3%0')  (' MAP2K3%0'  ' PIK3CA%0')  (' MAP2K3%0'  ' CREBBP%0')  (' MAP2K3%0'  ' PTPN11%0')  (' MAP2K3%0'  ' KRAS%0')  (' MAP2K3%0'  ' MAP2K4%0')  (' MAP2K3%0'  ' MAP2K7%0')  (' MAP2K3%0'  ' MAPK14%0')  (' MAP2K3%0'  ' JNK_f%0')  (' MAP2K3%0'  ' ERK_f%0')  (' MAP2K3%0'  ' LIF%0')  (' MAP2K3%0'  ' PPP1CA%0')  (' MAP2K3%0'  ' GAB_f%0')  (' MAP2K3%0'  ' SOS1%0')  (' MAP2K3%0'  ' PRKCA%0')  (' MAP2K3%0'  ' VAV1%0')  (' MAP2K3%0'  ' PLCG1%0')  (' MAP2K3%0'  ' PRKCD%0')  (' MAP2K3%0'  ' RSK_f%0')  (' MAP2K3%0'  ' S6K_f%0')  (' MAP2K3%0'  ' PLK1%0')  (' MAP2K3%0'  ' ILK%0')  (' MAP2K3%0'  ' SOCS1%0')  (' MAP2K3%0'  ' DUSP6%0')  (' MAP2K3%0'  ' STAT3%0')  (' MAP2K3%0'  ' LIMK2%0')  (' MAP2K3%0'  ' EP300%0')  (' MAP2K3%0'  ' STAT1%0')  (' MAP2K3%0'  ' IKBKB%0')  (' MAP2K3%0'  ' SRF%0')  (' MAP2K3%0'  ' PIAS1%0')  (' MAP2K3%0'  ' TRAF6%0')  (' MAP2K3%0'  ' SOCS1_g%0')  (' MAP2K3%0'  ' ISGF3_c%0')  (' MAP2K3%0'  ' STAT2%0')  (' MAP2K3%0'  ' CFLAR%0')  (' MAP2K3%0'  ' SMAD2%0')  (' MAP2K3%0'  ' MDM2_g%0')  (' MAP2K3%0'  ' BAX%0')  (' MAP2K3%0'  ' PRKACA%0')  (' MAP2K3%0'  ' TGFB1%0')  (' MAP2K3%0'  ' MAP3K8%0')  (' MAP2K3%0'  ' TSC_f%0')  (' MAP2K3%0'  ' SMAD4%0')  (' MAP2K3%0'  ' BAD%0')  (' MAP2K3%0'  ' MAP3K5%0')  (' MAP2K3%0'  ' AKT1S1%0')  (' MAP2K3%0'  ' SKI%0')  (' MAP2K3%0'  ' SMAD3%0')  (' MAP2K3%0'  ' MAPKAPK2%0')  (' MAP2K3%0'  ' DUSP1_g%0')  (' MAP2K3%0'  ' MSK_f%0')  (' MAP2K3%0'  ' GRAP2%0')  (' MAP2K3%0'  ' TAB_f%0')  (' MAP2K3%0'  ' ATF2%0')  (' MAP2K3%0'  ' SMAD5%0')  (' MAP2K3%0'  ' SMAD1%0')  (' MAP2K3%0'  ' FOS%0')  (' MAP2K3%0'  ' JUN%0')  (' MAP2K3%0'  ' MAP3K7%0')  (' MAP2K3%0'  ' NLK%0')  (' MAP2K3%0'  ' SMAD7_g%0')  (' MAP2K3%0'  ' SMAD6_g%0')  (' MAP2K3%0'  ' AP1_c%0')  (' MAP2K3%0'  ' ACVR1%0')  (' MAP2K3%0'  ' PTPN6%0')  (' MAP2K3%0'  ' CDC42%0')  (' MAP2K3%0'  ' GRB2%0')  (' MAP2K3%0'  ' TGFBR1%0')  (' MAP2K3%0'  ' SMURF1%0')  (' MAP2K3%0'  ' SMURF2%0')  (' MAP2K3%0'  ' RHOA%0')  (' MAP2K3%0'  ' BMPR2%0')  (' MAP2K3%0'  ' PARD6A%0')  (' MAP2K3%0'  ' DAAM1%0')  (' MAP2K3%0'  ' SFRP1_g%0')  (' MAP2K3%0'  ' PPM1A%0')  (' MAP2K3%0'  ' CFL_f%0')  (' MAP2K3%0'  ' PAK1%0')  (' MAP2K3%0'  ' MAP3K11%0')  (' MAP2K3%0'  ' MAP3K4%0')  (' MAP2K3%0'  ' LIMK1%0')  (' MAP2K3%0'  ' ROCK1%0')  (' MAP2K3%0'  ' ITCH%0')  (' MAP2K3%0'  ' ARHGAP24%0')  (' MAP2K3%0'  ' TIAM1%0')  (' MAP2K3%0'  ' RND3%0')  (' MAP2K3%0'  ' MAPK8IP3%0')  (' MAP2K3%0'  ' MXD1%0')  (' MAP2K3%0'  ' PIP3%0')  (' ERK_f%0'  ' SRC%0')  (' ERK_f%0'  ' CSK%0')  (' ERK_f%0'  ' CHUK%0')  (' ERK_f%0'  ' RAC_f%0')  (' ERK_f%0'  ' DUSP1%0')  (' ERK_f%0'  ' TGFBR2%0')  (' ERK_f%0'  ' ILR_f%0')  (' ERK_f%0'  ' SYK%0')  (' ERK_f%0'  ' IRAK1%0')  (' ERK_f%0'  ' SHC1%0')  (' ERK_f%0'  ' JAK_f%0')  (' ERK_f%0'  ' CBPp300_c%0')  (' ERK_f%0'  ' SKP2%0')  (' ERK_f%0'  ' TP53%0')  (' ERK_f%0'  ' SMAD7%0')  (' ERK_f%0'  ' SMAD6%0')  (' ERK_f%0'  ' DKK_f%0')  (' ERK_f%0'  ' FOXO_f%0')  (' ERK_f%0'  ' TCF7_f%0')  (' ERK_f%0'  ' DKK_g%0')  (' ERK_f%0'  ' MYC%0')  (' ERK_f%0'  ' CCND1%0')  (' ERK_f%0'  ' EGR1%0')  (' ERK_f%0'  ' MMP_f%0')  (' ERK_f%0'  ' PTEN_g%0')  (' ERK_f%0'  ' RTPK_f%0')  (' ERK_f%0'  ' CTNNB1%0')  (' ERK_f%0'  'LEF1%0')  (' ERK_f%0'  'SFRP1%0')  (' ERK_f%0'  'FZD_f%0')  (' ERK_f%0'  ' CASP8%0')  (' ERK_f%0'  ' REL_f%0')  (' ERK_f%0'  ' NFKB_f%0')  (' ERK_f%0'  ' DVL_f%0')  (' ERK_f%0'  ' LRP_f%0')  (' ERK_f%0'  ' BTRC%0')  (' ERK_f%0'  ' CK1_f%0')  (' ERK_f%0'  ' AXIN1%0')  (' ERK_f%0'  ' mTORC2_c%0')  (' ERK_f%0'  ' PDPK1%0')  (' ERK_f%0'  ' MEK_f%0')  (' ERK_f%0'  ' CYCS%0')  (' ERK_f%0'  ' CASP9%0')  (' ERK_f%0'  ' GSK3_f%0')  (' ERK_f%0'  ' IRS1%0')  (' ERK_f%0'  ' MDM2%0')  (' ERK_f%0'  ' AKT_f%0')  (' ERK_f%0'  ' BCL2%0')  (' ERK_f%0'  ' RAF_f%0')  (' ERK_f%0'  ' mTORC1_c%0')  (' ERK_f%0'  ' RHEB%0')  (' ERK_f%0'  ' RTPK_g%0')  (' ERK_f%0'  ' PTEN%0')  (' ERK_f%0'  ' CASP3%0')  (' ERK_f%0'  ' PIK3CA%0')  (' ERK_f%0'  ' CREBBP%0')  (' ERK_f%0'  ' PTPN11%0')  (' ERK_f%0'  ' KRAS%0')  (' ERK_f%0'  ' MAP2K4%0')  (' ERK_f%0'  ' MAP2K7%0')  (' ERK_f%0'  ' MAPK14%0')  (' ERK_f%0'  ' JNK_f%0')  (' ERK_f%0'  ' MAP2K3%0')  (' ERK_f%0'  ' LIF%0')  (' ERK_f%0'  ' PPP1CA%0')  (' ERK_f%0'  ' GAB_f%0')  (' ERK_f%0'  ' SOS1%0')  (' ERK_f%0'  ' PRKCA%0')  (' ERK_f%0'  ' VAV1%0')  (' ERK_f%0'  ' PLCG1%0')  (' ERK_f%0'  ' PRKCD%0')  (' ERK_f%0'  ' RSK_f%0')  (' ERK_f%0'  ' S6K_f%0')  (' ERK_f%0'  ' PLK1%0')  (' ERK_f%0'  ' ILK%0')  (' ERK_f%0'  ' SOCS1%0')  (' ERK_f%0'  ' DUSP6%0')  (' ERK_f%0'  ' STAT3%0')  (' ERK_f%0'  ' LIMK2%0')  (' ERK_f%0'  ' EP300%0')  (' ERK_f%0'  ' STAT1%0')  (' ERK_f%0'  ' IKBKB%0')  (' ERK_f%0'  ' SRF%0')  (' ERK_f%0'  ' PIAS1%0')  (' ERK_f%0'  ' TRAF6%0')  (' ERK_f%0'  ' SOCS1_g%0')  (' ERK_f%0'  ' ISGF3_c%0')  (' ERK_f%0'  ' STAT2%0')  (' ERK_f%0'  ' CFLAR%0')  (' ERK_f%0'  ' SMAD2%0')  (' ERK_f%0'  ' MDM2_g%0')  (' ERK_f%0'  ' BAX%0')  (' ERK_f%0'  ' PRKACA%0')  (' ERK_f%0'  ' TGFB1%0')  (' ERK_f%0'  ' MAP3K8%0')  (' ERK_f%0'  ' TSC_f%0')  (' ERK_f%0'  ' SMAD4%0')  (' ERK_f%0'  ' BAD%0')  (' ERK_f%0'  ' MAP3K5%0')  (' ERK_f%0'  ' AKT1S1%0')  (' ERK_f%0'  ' SKI%0')  (' ERK_f%0'  ' SMAD3%0')  (' ERK_f%0'  ' MAPKAPK2%0')  (' ERK_f%0'  ' DUSP1_g%0')  (' ERK_f%0'  ' MSK_f%0')  (' ERK_f%0'  ' GRAP2%0')  (' ERK_f%0'  ' TAB_f%0')  (' ERK_f%0'  ' ATF2%0')  (' ERK_f%0'  ' SMAD5%0')  (' ERK_f%0'  ' SMAD1%0')  (' ERK_f%0'  ' FOS%0')  (' ERK_f%0'  ' JUN%0')  (' ERK_f%0'  ' MAP3K7%0')  (' ERK_f%0'  ' NLK%0')  (' ERK_f%0'  ' SMAD7_g%0')  (' ERK_f%0'  ' SMAD6_g%0')  (' ERK_f%0'  ' AP1_c%0')  (' ERK_f%0'  ' ACVR1%0')  (' ERK_f%0'  ' PTPN6%0')  (' ERK_f%0'  ' CDC42%0')  (' ERK_f%0'  ' GRB2%0')  (' ERK_f%0'  ' TGFBR1%0')  (' ERK_f%0'  ' SMURF1%0')  (' ERK_f%0'  ' SMURF2%0')  (' ERK_f%0'  ' RHOA%0')  (' ERK_f%0'  ' BMPR2%0')  (' ERK_f%0'  ' PARD6A%0')  (' ERK_f%0'  ' DAAM1%0')  (' ERK_f%0'  ' SFRP1_g%0')  (' ERK_f%0'  ' PPM1A%0')  (' ERK_f%0'  ' CFL_f%0')  (' ERK_f%0'  ' PAK1%0')  (' ERK_f%0'  ' MAP3K11%0')  (' ERK_f%0'  ' MAP3K4%0')  (' ERK_f%0'  ' LIMK1%0')  (' ERK_f%0'  ' ROCK1%0')  (' ERK_f%0'  ' ITCH%0')  (' ERK_f%0'  ' ARHGAP24%0')  (' ERK_f%0'  ' TIAM1%0')  (' ERK_f%0'  ' RND3%0')  (' ERK_f%0'  ' MAPK8IP3%0')  (' ERK_f%0'  ' MXD1%0')  (' ERK_f%0'  ' PIP3%0')  (' LIF%0'  ' SRC%0')  (' LIF%0'  ' CSK%0')  (' LIF%0'  ' CHUK%0')  (' LIF%0'  ' RAC_f%0')  (' LIF%0'  ' DUSP1%0')  (' LIF%0'  ' TGFBR2%0')  (' LIF%0'  ' ILR_f%0')  (' LIF%0'  ' SYK%0')  (' LIF%0'  ' IRAK1%0')  (' LIF%0'  ' SHC1%0')  (' LIF%0'  ' JAK_f%0')  (' LIF%0'  ' CBPp300_c%0')  (' LIF%0'  ' SKP2%0')  (' LIF%0'  ' TP53%0')  (' LIF%0'  ' SMAD7%0')  (' LIF%0'  ' SMAD6%0')  (' LIF%0'  ' DKK_f%0')  (' LIF%0'  ' FOXO_f%0')  (' LIF%0'  ' TCF7_f%0')  (' LIF%0'  ' DKK_g%0')  (' LIF%0'  ' MYC%0')  (' LIF%0'  ' CCND1%0')  (' LIF%0'  ' EGR1%0')  (' LIF%0'  ' MMP_f%0')  (' LIF%0'  ' PTEN_g%0')  (' LIF%0'  ' RTPK_f%0')  (' LIF%0'  ' CTNNB1%0')  (' LIF%0'  'LEF1%0')  (' LIF%0'  'SFRP1%0')  (' LIF%0'  'FZD_f%0')  (' LIF%0'  ' CASP8%0')  (' LIF%0'  ' REL_f%0')  (' LIF%0'  ' NFKB_f%0')  (' LIF%0'  ' DVL_f%0')  (' LIF%0'  ' LRP_f%0')  (' LIF%0'  ' BTRC%0')  (' LIF%0'  ' CK1_f%0')  (' LIF%0'  ' AXIN1%0')  (' LIF%0'  ' mTORC2_c%0')  (' LIF%0'  ' PDPK1%0')  (' LIF%0'  ' MEK_f%0')  (' LIF%0'  ' CYCS%0')  (' LIF%0'  ' CASP9%0')  (' LIF%0'  ' GSK3_f%0')  (' LIF%0'  ' IRS1%0')  (' LIF%0'  ' MDM2%0')  (' LIF%0'  ' AKT_f%0')  (' LIF%0'  ' BCL2%0')  (' LIF%0'  ' RAF_f%0')  (' LIF%0'  ' mTORC1_c%0')  (' LIF%0'  ' RHEB%0')  (' LIF%0'  ' RTPK_g%0')  (' LIF%0'  ' PTEN%0')  (' LIF%0'  ' CASP3%0')  (' LIF%0'  ' PIK3CA%0')  (' LIF%0'  ' CREBBP%0')  (' LIF%0'  ' PTPN11%0')  (' LIF%0'  ' KRAS%0')  (' LIF%0'  ' MAP2K4%0')  (' LIF%0'  ' MAP2K7%0')  (' LIF%0'  ' MAPK14%0')  (' LIF%0'  ' JNK_f%0')  (' LIF%0'  ' MAP2K3%0')  (' LIF%0'  ' ERK_f%0')  (' LIF%0'  ' PPP1CA%0')  (' LIF%0'  ' GAB_f%0')  (' LIF%0'  ' SOS1%0')  (' LIF%0'  ' PRKCA%0')  (' LIF%0'  ' VAV1%0')  (' LIF%0'  ' PLCG1%0')  (' LIF%0'  ' PRKCD%0')  (' LIF%0'  ' RSK_f%0')  (' LIF%0'  ' S6K_f%0')  (' LIF%0'  ' PLK1%0')  (' LIF%0'  ' ILK%0')  (' LIF%0'  ' SOCS1%0')  (' LIF%0'  ' DUSP6%0')  (' LIF%0'  ' STAT3%0')  (' LIF%0'  ' LIMK2%0')  (' LIF%0'  ' EP300%0')  (' LIF%0'  ' STAT1%0')  (' LIF%0'  ' IKBKB%0')  (' LIF%0'  ' SRF%0')  (' LIF%0'  ' PIAS1%0')  (' LIF%0'  ' TRAF6%0')  (' LIF%0'  ' SOCS1_g%0')  (' LIF%0'  ' ISGF3_c%0')  (' LIF%0'  ' STAT2%0')  (' LIF%0'  ' CFLAR%0')  (' LIF%0'  ' SMAD2%0')  (' LIF%0'  ' MDM2_g%0')  (' LIF%0'  ' BAX%0')  (' LIF%0'  ' PRKACA%0')  (' LIF%0'  ' TGFB1%0')  (' LIF%0'  ' MAP3K8%0')  (' LIF%0'  ' TSC_f%0')  (' LIF%0'  ' SMAD4%0')  (' LIF%0'  ' BAD%0')  (' LIF%0'  ' MAP3K5%0')  (' LIF%0'  ' AKT1S1%0')  (' LIF%0'  ' SKI%0')  (' LIF%0'  ' SMAD3%0')  (' LIF%0'  ' MAPKAPK2%0')  (' LIF%0'  ' DUSP1_g%0')  (' LIF%0'  ' MSK_f%0')  (' LIF%0'  ' GRAP2%0')  (' LIF%0'  ' TAB_f%0')  (' LIF%0'  ' ATF2%0')  (' LIF%0'  ' SMAD5%0')  (' LIF%0'  ' SMAD1%0')  (' LIF%0'  ' FOS%0')  (' LIF%0'  ' JUN%0')  (' LIF%0'  ' MAP3K7%0')  (' LIF%0'  ' NLK%0')  (' LIF%0'  ' SMAD7_g%0')  (' LIF%0'  ' SMAD6_g%0')  (' LIF%0'  ' AP1_c%0')  (' LIF%0'  ' ACVR1%0')  (' LIF%0'  ' PTPN6%0')  (' LIF%0'  ' CDC42%0')  (' LIF%0'  ' GRB2%0')  (' LIF%0'  ' TGFBR1%0')  (' LIF%0'  ' SMURF1%0')  (' LIF%0'  ' SMURF2%0')  (' LIF%0'  ' RHOA%0')  (' LIF%0'  ' BMPR2%0')  (' LIF%0'  ' PARD6A%0')  (' LIF%0'  ' DAAM1%0')  (' LIF%0'  ' SFRP1_g%0')  (' LIF%0'  ' PPM1A%0')  (' LIF%0'  ' CFL_f%0')  (' LIF%0'  ' PAK1%0')  (' LIF%0'  ' MAP3K11%0')  (' LIF%0'  ' MAP3K4%0')  (' LIF%0'  ' LIMK1%0')  (' LIF%0'  ' ROCK1%0')  (' LIF%0'  ' ITCH%0')  (' LIF%0'  ' ARHGAP24%0')  (' LIF%0'  ' TIAM1%0')  (' LIF%0'  ' RND3%0')  (' LIF%0'  ' MAPK8IP3%0')  (' LIF%0'  ' MXD1%0')  (' LIF%0'  ' PIP3%0')  (' PPP1CA%0'  ' SRC%0')  (' PPP1CA%0'  ' CSK%0')  (' PPP1CA%0'  ' CHUK%0')  (' PPP1CA%0'  ' RAC_f%0')  (' PPP1CA%0'  ' DUSP1%0')  (' PPP1CA%0'  ' TGFBR2%0')  (' PPP1CA%0'  ' ILR_f%0')  (' PPP1CA%0'  ' SYK%0')  (' PPP1CA%0'  ' IRAK1%0')  (' PPP1CA%0'  ' SHC1%0')  (' PPP1CA%0'  ' JAK_f%0')  (' PPP1CA%0'  ' CBPp300_c%0')  (' PPP1CA%0'  ' SKP2%0')  (' PPP1CA%0'  ' TP53%0')  (' PPP1CA%0'  ' SMAD7%0')  (' PPP1CA%0'  ' SMAD6%0')  (' PPP1CA%0'  ' DKK_f%0')  (' PPP1CA%0'  ' FOXO_f%0')  (' PPP1CA%0'  ' TCF7_f%0')  (' PPP1CA%0'  ' DKK_g%0')  (' PPP1CA%0'  ' MYC%0')  (' PPP1CA%0'  ' CCND1%0')  (' PPP1CA%0'  ' EGR1%0')  (' PPP1CA%0'  ' MMP_f%0')  (' PPP1CA%0'  ' PTEN_g%0')  (' PPP1CA%0'  ' RTPK_f%0')  (' PPP1CA%0'  ' CTNNB1%0')  (' PPP1CA%0'  'LEF1%0')  (' PPP1CA%0'  'SFRP1%0')  (' PPP1CA%0'  'FZD_f%0')  (' PPP1CA%0'  ' CASP8%0')  (' PPP1CA%0'  ' REL_f%0')  (' PPP1CA%0'  ' NFKB_f%0')  (' PPP1CA%0'  ' DVL_f%0')  (' PPP1CA%0'  ' LRP_f%0')  (' PPP1CA%0'  ' BTRC%0')  (' PPP1CA%0'  ' CK1_f%0')  (' PPP1CA%0'  ' AXIN1%0')  (' PPP1CA%0'  ' mTORC2_c%0')  (' PPP1CA%0'  ' PDPK1%0')  (' PPP1CA%0'  ' MEK_f%0')  (' PPP1CA%0'  ' CYCS%0')  (' PPP1CA%0'  ' CASP9%0')  (' PPP1CA%0'  ' GSK3_f%0')  (' PPP1CA%0'  ' IRS1%0')  (' PPP1CA%0'  ' MDM2%0')  (' PPP1CA%0'  ' AKT_f%0')  (' PPP1CA%0'  ' BCL2%0')  (' PPP1CA%0'  ' RAF_f%0')  (' PPP1CA%0'  ' mTORC1_c%0')  (' PPP1CA%0'  ' RHEB%0')  (' PPP1CA%0'  ' RTPK_g%0')  (' PPP1CA%0'  ' PTEN%0')  (' PPP1CA%0'  ' CASP3%0')  (' PPP1CA%0'  ' PIK3CA%0')  (' PPP1CA%0'  ' CREBBP%0')  (' PPP1CA%0'  ' PTPN11%0')  (' PPP1CA%0'  ' KRAS%0')  (' PPP1CA%0'  ' MAP2K4%0')  (' PPP1CA%0'  ' MAP2K7%0')  (' PPP1CA%0'  ' MAPK14%0')  (' PPP1CA%0'  ' JNK_f%0')  (' PPP1CA%0'  ' MAP2K3%0')  (' PPP1CA%0'  ' ERK_f%0')  (' PPP1CA%0'  ' LIF%0')  (' PPP1CA%0'  ' GAB_f%0')  (' PPP1CA%0'  ' SOS1%0')  (' PPP1CA%0'  ' PRKCA%0')  (' PPP1CA%0'  ' VAV1%0')  (' PPP1CA%0'  ' PLCG1%0')  (' PPP1CA%0'  ' PRKCD%0')  (' PPP1CA%0'  ' RSK_f%0')  (' PPP1CA%0'  ' S6K_f%0')  (' PPP1CA%0'  ' PLK1%0')  (' PPP1CA%0'  ' ILK%0')  (' PPP1CA%0'  ' SOCS1%0')  (' PPP1CA%0'  ' DUSP6%0')  (' PPP1CA%0'  ' STAT3%0')  (' PPP1CA%0'  ' LIMK2%0')  (' PPP1CA%0'  ' EP300%0')  (' PPP1CA%0'  ' STAT1%0')  (' PPP1CA%0'  ' IKBKB%0')  (' PPP1CA%0'  ' SRF%0')  (' PPP1CA%0'  ' PIAS1%0')  (' PPP1CA%0'  ' TRAF6%0')  (' PPP1CA%0'  ' SOCS1_g%0')  (' PPP1CA%0'  ' ISGF3_c%0')  (' PPP1CA%0'  ' STAT2%0')  (' PPP1CA%0'  ' CFLAR%0')  (' PPP1CA%0'  ' SMAD2%0')  (' PPP1CA%0'  ' MDM2_g%0')  (' PPP1CA%0'  ' BAX%0')  (' PPP1CA%0'  ' PRKACA%0')  (' PPP1CA%0'  ' TGFB1%0')  (' PPP1CA%0'  ' MAP3K8%0')  (' PPP1CA%0'  ' TSC_f%0')  (' PPP1CA%0'  ' SMAD4%0')  (' PPP1CA%0'  ' BAD%0')  (' PPP1CA%0'  ' MAP3K5%0')  (' PPP1CA%0'  ' AKT1S1%0')  (' PPP1CA%0'  ' SKI%0')  (' PPP1CA%0'  ' SMAD3%0')  (' PPP1CA%0'  ' MAPKAPK2%0')  (' PPP1CA%0'  ' DUSP1_g%0')  (' PPP1CA%0'  ' MSK_f%0')  (' PPP1CA%0'  ' GRAP2%0')  (' PPP1CA%0'  ' TAB_f%0')  (' PPP1CA%0'  ' ATF2%0')  (' PPP1CA%0'  ' SMAD5%0')  (' PPP1CA%0'  ' SMAD1%0')  (' PPP1CA%0'  ' FOS%0')  (' PPP1CA%0'  ' JUN%0')  (' PPP1CA%0'  ' MAP3K7%0')  (' PPP1CA%0'  ' NLK%0')  (' PPP1CA%0'  ' SMAD7_g%0')  (' PPP1CA%0'  ' SMAD6_g%0')  (' PPP1CA%0'  ' AP1_c%0')  (' PPP1CA%0'  ' ACVR1%0')  (' PPP1CA%0'  ' PTPN6%0')  (' PPP1CA%0'  ' CDC42%0')  (' PPP1CA%0'  ' GRB2%0')  (' PPP1CA%0'  ' TGFBR1%0')  (' PPP1CA%0'  ' SMURF1%0')  (' PPP1CA%0'  ' SMURF2%0')  (' PPP1CA%0'  ' RHOA%0')  (' PPP1CA%0'  ' BMPR2%0')  (' PPP1CA%0'  ' PARD6A%0')  (' PPP1CA%0'  ' DAAM1%0')  (' PPP1CA%0'  ' SFRP1_g%0')  (' PPP1CA%0'  ' PPM1A%0')  (' PPP1CA%0'  ' CFL_f%0')  (' PPP1CA%0'  ' PAK1%0')  (' PPP1CA%0'  ' MAP3K11%0')  (' PPP1CA%0'  ' MAP3K4%0')  (' PPP1CA%0'  ' LIMK1%0')  (' PPP1CA%0'  ' ROCK1%0')  (' PPP1CA%0'  ' ITCH%0')  (' PPP1CA%0'  ' ARHGAP24%0')  (' PPP1CA%0'  ' TIAM1%0')  (' PPP1CA%0'  ' RND3%0')  (' PPP1CA%0'  ' MAPK8IP3%0')  (' PPP1CA%0'  ' MXD1%0')  (' PPP1CA%0'  ' PIP3%0')  (' GAB_f%0'  ' SRC%0')  (' GAB_f%0'  ' CSK%0')  (' GAB_f%0'  ' CHUK%0')  (' GAB_f%0'  ' RAC_f%0')  (' GAB_f%0'  ' DUSP1%0')  (' GAB_f%0'  ' TGFBR2%0')  (' GAB_f%0'  ' ILR_f%0')  (' GAB_f%0'  ' SYK%0')  (' GAB_f%0'  ' IRAK1%0')  (' GAB_f%0'  ' SHC1%0')  (' GAB_f%0'  ' JAK_f%0')  (' GAB_f%0'  ' CBPp300_c%0')  (' GAB_f%0'  ' SKP2%0')  (' GAB_f%0'  ' TP53%0')  (' GAB_f%0'  ' SMAD7%0')  (' GAB_f%0'  ' SMAD6%0')  (' GAB_f%0'  ' DKK_f%0')  (' GAB_f%0'  ' FOXO_f%0')  (' GAB_f%0'  ' TCF7_f%0')  (' GAB_f%0'  ' DKK_g%0')  (' GAB_f%0'  ' MYC%0')  (' GAB_f%0'  ' CCND1%0')  (' GAB_f%0'  ' EGR1%0')  (' GAB_f%0'  ' MMP_f%0')  (' GAB_f%0'  ' PTEN_g%0')  (' GAB_f%0'  ' RTPK_f%0')  (' GAB_f%0'  ' CTNNB1%0')  (' GAB_f%0'  'LEF1%0')  (' GAB_f%0'  'SFRP1%0')  (' GAB_f%0'  'FZD_f%0')  (' GAB_f%0'  ' CASP8%0')  (' GAB_f%0'  ' REL_f%0')  (' GAB_f%0'  ' NFKB_f%0')  (' GAB_f%0'  ' DVL_f%0')  (' GAB_f%0'  ' LRP_f%0')  (' GAB_f%0'  ' BTRC%0')  (' GAB_f%0'  ' CK1_f%0')  (' GAB_f%0'  ' AXIN1%0')  (' GAB_f%0'  ' mTORC2_c%0')  (' GAB_f%0'  ' PDPK1%0')  (' GAB_f%0'  ' MEK_f%0')  (' GAB_f%0'  ' CYCS%0')  (' GAB_f%0'  ' CASP9%0')  (' GAB_f%0'  ' GSK3_f%0')  (' GAB_f%0'  ' IRS1%0')  (' GAB_f%0'  ' MDM2%0')  (' GAB_f%0'  ' AKT_f%0')  (' GAB_f%0'  ' BCL2%0')  (' GAB_f%0'  ' RAF_f%0')  (' GAB_f%0'  ' mTORC1_c%0')  (' GAB_f%0'  ' RHEB%0')  (' GAB_f%0'  ' RTPK_g%0')  (' GAB_f%0'  ' PTEN%0')  (' GAB_f%0'  ' CASP3%0')  (' GAB_f%0'  ' PIK3CA%0')  (' GAB_f%0'  ' CREBBP%0')  (' GAB_f%0'  ' PTPN11%0')  (' GAB_f%0'  ' KRAS%0')  (' GAB_f%0'  ' MAP2K4%0')  (' GAB_f%0'  ' MAP2K7%0')  (' GAB_f%0'  ' MAPK14%0')  (' GAB_f%0'  ' JNK_f%0')  (' GAB_f%0'  ' MAP2K3%0')  (' GAB_f%0'  ' ERK_f%0')  (' GAB_f%0'  ' LIF%0')  (' GAB_f%0'  ' PPP1CA%0')  (' GAB_f%0'  ' SOS1%0')  (' GAB_f%0'  ' PRKCA%0')  (' GAB_f%0'  ' VAV1%0')  (' GAB_f%0'  ' PLCG1%0')  (' GAB_f%0'  ' PRKCD%0')  (' GAB_f%0'  ' RSK_f%0')  (' GAB_f%0'  ' S6K_f%0')  (' GAB_f%0'  ' PLK1%0')  (' GAB_f%0'  ' ILK%0')  (' GAB_f%0'  ' SOCS1%0')  (' GAB_f%0'  ' DUSP6%0')  (' GAB_f%0'  ' STAT3%0')  (' GAB_f%0'  ' LIMK2%0')  (' GAB_f%0'  ' EP300%0')  (' GAB_f%0'  ' STAT1%0')  (' GAB_f%0'  ' IKBKB%0')  (' GAB_f%0'  ' SRF%0')  (' GAB_f%0'  ' PIAS1%0')  (' GAB_f%0'  ' TRAF6%0')  (' GAB_f%0'  ' SOCS1_g%0')  (' GAB_f%0'  ' ISGF3_c%0')  (' GAB_f%0'  ' STAT2%0')  (' GAB_f%0'  ' CFLAR%0')  (' GAB_f%0'  ' SMAD2%0')  (' GAB_f%0'  ' MDM2_g%0')  (' GAB_f%0'  ' BAX%0')  (' GAB_f%0'  ' PRKACA%0')  (' GAB_f%0'  ' TGFB1%0')  (' GAB_f%0'  ' MAP3K8%0')  (' GAB_f%0'  ' TSC_f%0')  (' GAB_f%0'  ' SMAD4%0')  (' GAB_f%0'  ' BAD%0')  (' GAB_f%0'  ' MAP3K5%0')  (' GAB_f%0'  ' AKT1S1%0')  (' GAB_f%0'  ' SKI%0')  (' GAB_f%0'  ' SMAD3%0')  (' GAB_f%0'  ' MAPKAPK2%0')  (' GAB_f%0'  ' DUSP1_g%0')  (' GAB_f%0'  ' MSK_f%0')  (' GAB_f%0'  ' GRAP2%0')  (' GAB_f%0'  ' TAB_f%0')  (' GAB_f%0'  ' ATF2%0')  (' GAB_f%0'  ' SMAD5%0')  (' GAB_f%0'  ' SMAD1%0')  (' GAB_f%0'  ' FOS%0')  (' GAB_f%0'  ' JUN%0')  (' GAB_f%0'  ' MAP3K7%0')  (' GAB_f%0'  ' NLK%0')  (' GAB_f%0'  ' SMAD7_g%0')  (' GAB_f%0'  ' SMAD6_g%0')  (' GAB_f%0'  ' AP1_c%0')  (' GAB_f%0'  ' ACVR1%0')  (' GAB_f%0'  ' PTPN6%0')  (' GAB_f%0'  ' CDC42%0')  (' GAB_f%0'  ' GRB2%0')  (' GAB_f%0'  ' TGFBR1%0')  (' GAB_f%0'  ' SMURF1%0')  (' GAB_f%0'  ' SMURF2%0')  (' GAB_f%0'  ' RHOA%0')  (' GAB_f%0'  ' BMPR2%0')  (' GAB_f%0'  ' PARD6A%0')  (' GAB_f%0'  ' DAAM1%0')  (' GAB_f%0'  ' SFRP1_g%0')  (' GAB_f%0'  ' PPM1A%0')  (' GAB_f%0'  ' CFL_f%0')  (' GAB_f%0'  ' PAK1%0')  (' GAB_f%0'  ' MAP3K11%0')  (' GAB_f%0'  ' MAP3K4%0')  (' GAB_f%0'  ' LIMK1%0')  (' GAB_f%0'  ' ROCK1%0')  (' GAB_f%0'  ' ITCH%0')  (' GAB_f%0'  ' ARHGAP24%0')  (' GAB_f%0'  ' TIAM1%0')  (' GAB_f%0'  ' RND3%0')  (' GAB_f%0'  ' MAPK8IP3%0')  (' GAB_f%0'  ' MXD1%0')  (' GAB_f%0'  ' PIP3%0')  (' SOS1%0'  ' SRC%0')  (' SOS1%0'  ' CSK%0')  (' SOS1%0'  ' CHUK%0')  (' SOS1%0'  ' RAC_f%0')  (' SOS1%0'  ' DUSP1%0')  (' SOS1%0'  ' TGFBR2%0')  (' SOS1%0'  ' ILR_f%0')  (' SOS1%0'  ' SYK%0')  (' SOS1%0'  ' IRAK1%0')  (' SOS1%0'  ' SHC1%0')  (' SOS1%0'  ' JAK_f%0')  (' SOS1%0'  ' CBPp300_c%0')  (' SOS1%0'  ' SKP2%0')  (' SOS1%0'  ' TP53%0')  (' SOS1%0'  ' SMAD7%0')  (' SOS1%0'  ' SMAD6%0')  (' SOS1%0'  ' DKK_f%0')  (' SOS1%0'  ' FOXO_f%0')  (' SOS1%0'  ' TCF7_f%0')  (' SOS1%0'  ' DKK_g%0')  (' SOS1%0'  ' MYC%0')  (' SOS1%0'  ' CCND1%0')  (' SOS1%0'  ' EGR1%0')  (' SOS1%0'  ' MMP_f%0')  (' SOS1%0'  ' PTEN_g%0')  (' SOS1%0'  ' RTPK_f%0')  (' SOS1%0'  ' CTNNB1%0')  (' SOS1%0'  'LEF1%0')  (' SOS1%0'  'SFRP1%0')  (' SOS1%0'  'FZD_f%0')  (' SOS1%0'  ' CASP8%0')  (' SOS1%0'  ' REL_f%0')  (' SOS1%0'  ' NFKB_f%0')  (' SOS1%0'  ' DVL_f%0')  (' SOS1%0'  ' LRP_f%0')  (' SOS1%0'  ' BTRC%0')  (' SOS1%0'  ' CK1_f%0')  (' SOS1%0'  ' AXIN1%0')  (' SOS1%0'  ' mTORC2_c%0')  (' SOS1%0'  ' PDPK1%0')  (' SOS1%0'  ' MEK_f%0')  (' SOS1%0'  ' CYCS%0')  (' SOS1%0'  ' CASP9%0')  (' SOS1%0'  ' GSK3_f%0')  (' SOS1%0'  ' IRS1%0')  (' SOS1%0'  ' MDM2%0')  (' SOS1%0'  ' AKT_f%0')  (' SOS1%0'  ' BCL2%0')  (' SOS1%0'  ' RAF_f%0')  (' SOS1%0'  ' mTORC1_c%0')  (' SOS1%0'  ' RHEB%0')  (' SOS1%0'  ' RTPK_g%0')  (' SOS1%0'  ' PTEN%0')  (' SOS1%0'  ' CASP3%0')  (' SOS1%0'  ' PIK3CA%0')  (' SOS1%0'  ' CREBBP%0')  (' SOS1%0'  ' PTPN11%0')  (' SOS1%0'  ' KRAS%0')  (' SOS1%0'  ' MAP2K4%0')  (' SOS1%0'  ' MAP2K7%0')  (' SOS1%0'  ' MAPK14%0')  (' SOS1%0'  ' JNK_f%0')  (' SOS1%0'  ' MAP2K3%0')  (' SOS1%0'  ' ERK_f%0')  (' SOS1%0'  ' LIF%0')  (' SOS1%0'  ' PPP1CA%0')  (' SOS1%0'  ' GAB_f%0')  (' SOS1%0'  ' PRKCA%0')  (' SOS1%0'  ' VAV1%0')  (' SOS1%0'  ' PLCG1%0')  (' SOS1%0'  ' PRKCD%0')  (' SOS1%0'  ' RSK_f%0')  (' SOS1%0'  ' S6K_f%0')  (' SOS1%0'  ' PLK1%0')  (' SOS1%0'  ' ILK%0')  (' SOS1%0'  ' SOCS1%0')  (' SOS1%0'  ' DUSP6%0')  (' SOS1%0'  ' STAT3%0')  (' SOS1%0'  ' LIMK2%0')  (' SOS1%0'  ' EP300%0')  (' SOS1%0'  ' STAT1%0')  (' SOS1%0'  ' IKBKB%0')  (' SOS1%0'  ' SRF%0')  (' SOS1%0'  ' PIAS1%0')  (' SOS1%0'  ' TRAF6%0')  (' SOS1%0'  ' SOCS1_g%0')  (' SOS1%0'  ' ISGF3_c%0')  (' SOS1%0'  ' STAT2%0')  (' SOS1%0'  ' CFLAR%0')  (' SOS1%0'  ' SMAD2%0')  (' SOS1%0'  ' MDM2_g%0')  (' SOS1%0'  ' BAX%0')  (' SOS1%0'  ' PRKACA%0')  (' SOS1%0'  ' TGFB1%0')  (' SOS1%0'  ' MAP3K8%0')  (' SOS1%0'  ' TSC_f%0')  (' SOS1%0'  ' SMAD4%0')  (' SOS1%0'  ' BAD%0')  (' SOS1%0'  ' MAP3K5%0')  (' SOS1%0'  ' AKT1S1%0')  (' SOS1%0'  ' SKI%0')  (' SOS1%0'  ' SMAD3%0')  (' SOS1%0'  ' MAPKAPK2%0')  (' SOS1%0'  ' DUSP1_g%0')  (' SOS1%0'  ' MSK_f%0')  (' SOS1%0'  ' GRAP2%0')  (' SOS1%0'  ' TAB_f%0')  (' SOS1%0'  ' ATF2%0')  (' SOS1%0'  ' SMAD5%0')  (' SOS1%0'  ' SMAD1%0')  (' SOS1%0'  ' FOS%0')  (' SOS1%0'  ' JUN%0')  (' SOS1%0'  ' MAP3K7%0')  (' SOS1%0'  ' NLK%0')  (' SOS1%0'  ' SMAD7_g%0')  (' SOS1%0'  ' SMAD6_g%0')  (' SOS1%0'  ' AP1_c%0')  (' SOS1%0'  ' ACVR1%0')  (' SOS1%0'  ' PTPN6%0')  (' SOS1%0'  ' CDC42%0')  (' SOS1%0'  ' GRB2%0')  (' SOS1%0'  ' TGFBR1%0')  (' SOS1%0'  ' SMURF1%0')  (' SOS1%0'  ' SMURF2%0')  (' SOS1%0'  ' RHOA%0')  (' SOS1%0'  ' BMPR2%0')  (' SOS1%0'  ' PARD6A%0')  (' SOS1%0'  ' DAAM1%0')  (' SOS1%0'  ' SFRP1_g%0')  (' SOS1%0'  ' PPM1A%0')  (' SOS1%0'  ' CFL_f%0')  (' SOS1%0'  ' PAK1%0')  (' SOS1%0'  ' MAP3K11%0')  (' SOS1%0'  ' MAP3K4%0')  (' SOS1%0'  ' LIMK1%0')  (' SOS1%0'  ' ROCK1%0')  (' SOS1%0'  ' ITCH%0')  (' SOS1%0'  ' ARHGAP24%0')  (' SOS1%0'  ' TIAM1%0')  (' SOS1%0'  ' RND3%0')  (' SOS1%0'  ' MAPK8IP3%0')  (' SOS1%0'  ' MXD1%0')  (' SOS1%0'  ' PIP3%0')  (' PRKCA%0'  ' SRC%0')  (' PRKCA%0'  ' CSK%0')  (' PRKCA%0'  ' CHUK%0')  (' PRKCA%0'  ' RAC_f%0')  (' PRKCA%0'  ' DUSP1%0')  (' PRKCA%0'  ' TGFBR2%0')  (' PRKCA%0'  ' ILR_f%0')  (' PRKCA%0'  ' SYK%0')  (' PRKCA%0'  ' IRAK1%0')  (' PRKCA%0'  ' SHC1%0')  (' PRKCA%0'  ' JAK_f%0')  (' PRKCA%0'  ' CBPp300_c%0')  (' PRKCA%0'  ' SKP2%0')  (' PRKCA%0'  ' TP53%0')  (' PRKCA%0'  ' SMAD7%0')  (' PRKCA%0'  ' SMAD6%0')  (' PRKCA%0'  ' DKK_f%0')  (' PRKCA%0'  ' FOXO_f%0')  (' PRKCA%0'  ' TCF7_f%0')  (' PRKCA%0'  ' DKK_g%0')  (' PRKCA%0'  ' MYC%0')  (' PRKCA%0'  ' CCND1%0')  (' PRKCA%0'  ' EGR1%0')  (' PRKCA%0'  ' MMP_f%0')  (' PRKCA%0'  ' PTEN_g%0')  (' PRKCA%0'  ' RTPK_f%0')  (' PRKCA%0'  ' CTNNB1%0')  (' PRKCA%0'  'LEF1%0')  (' PRKCA%0'  'SFRP1%0')  (' PRKCA%0'  'FZD_f%0')  (' PRKCA%0'  ' CASP8%0')  (' PRKCA%0'  ' REL_f%0')  (' PRKCA%0'  ' NFKB_f%0')  (' PRKCA%0'  ' DVL_f%0')  (' PRKCA%0'  ' LRP_f%0')  (' PRKCA%0'  ' BTRC%0')  (' PRKCA%0'  ' CK1_f%0')  (' PRKCA%0'  ' AXIN1%0')  (' PRKCA%0'  ' mTORC2_c%0')  (' PRKCA%0'  ' PDPK1%0')  (' PRKCA%0'  ' MEK_f%0')  (' PRKCA%0'  ' CYCS%0')  (' PRKCA%0'  ' CASP9%0')  (' PRKCA%0'  ' GSK3_f%0')  (' PRKCA%0'  ' IRS1%0')  (' PRKCA%0'  ' MDM2%0')  (' PRKCA%0'  ' AKT_f%0')  (' PRKCA%0'  ' BCL2%0')  (' PRKCA%0'  ' RAF_f%0')  (' PRKCA%0'  ' mTORC1_c%0')  (' PRKCA%0'  ' RHEB%0')  (' PRKCA%0'  ' RTPK_g%0')  (' PRKCA%0'  ' PTEN%0')  (' PRKCA%0'  ' CASP3%0')  (' PRKCA%0'  ' PIK3CA%0')  (' PRKCA%0'  ' CREBBP%0')  (' PRKCA%0'  ' PTPN11%0')  (' PRKCA%0'  ' KRAS%0')  (' PRKCA%0'  ' MAP2K4%0')  (' PRKCA%0'  ' MAP2K7%0')  (' PRKCA%0'  ' MAPK14%0')  (' PRKCA%0'  ' JNK_f%0')  (' PRKCA%0'  ' MAP2K3%0')  (' PRKCA%0'  ' ERK_f%0')  (' PRKCA%0'  ' LIF%0')  (' PRKCA%0'  ' PPP1CA%0')  (' PRKCA%0'  ' GAB_f%0')  (' PRKCA%0'  ' SOS1%0')  (' PRKCA%0'  ' VAV1%0')  (' PRKCA%0'  ' PLCG1%0')  (' PRKCA%0'  ' PRKCD%0')  (' PRKCA%0'  ' RSK_f%0')  (' PRKCA%0'  ' S6K_f%0')  (' PRKCA%0'  ' PLK1%0')  (' PRKCA%0'  ' ILK%0')  (' PRKCA%0'  ' SOCS1%0')  (' PRKCA%0'  ' DUSP6%0')  (' PRKCA%0'  ' STAT3%0')  (' PRKCA%0'  ' LIMK2%0')  (' PRKCA%0'  ' EP300%0')  (' PRKCA%0'  ' STAT1%0')  (' PRKCA%0'  ' IKBKB%0')  (' PRKCA%0'  ' SRF%0')  (' PRKCA%0'  ' PIAS1%0')  (' PRKCA%0'  ' TRAF6%0')  (' PRKCA%0'  ' SOCS1_g%0')  (' PRKCA%0'  ' ISGF3_c%0')  (' PRKCA%0'  ' STAT2%0')  (' PRKCA%0'  ' CFLAR%0')  (' PRKCA%0'  ' SMAD2%0')  (' PRKCA%0'  ' MDM2_g%0')  (' PRKCA%0'  ' BAX%0')  (' PRKCA%0'  ' PRKACA%0')  (' PRKCA%0'  ' TGFB1%0')  (' PRKCA%0'  ' MAP3K8%0')  (' PRKCA%0'  ' TSC_f%0')  (' PRKCA%0'  ' SMAD4%0')  (' PRKCA%0'  ' BAD%0')  (' PRKCA%0'  ' MAP3K5%0')  (' PRKCA%0'  ' AKT1S1%0')  (' PRKCA%0'  ' SKI%0')  (' PRKCA%0'  ' SMAD3%0')  (' PRKCA%0'  ' MAPKAPK2%0')  (' PRKCA%0'  ' DUSP1_g%0')  (' PRKCA%0'  ' MSK_f%0')  (' PRKCA%0'  ' GRAP2%0')  (' PRKCA%0'  ' TAB_f%0')  (' PRKCA%0'  ' ATF2%0')  (' PRKCA%0'  ' SMAD5%0')  (' PRKCA%0'  ' SMAD1%0')  (' PRKCA%0'  ' FOS%0')  (' PRKCA%0'  ' JUN%0')  (' PRKCA%0'  ' MAP3K7%0')  (' PRKCA%0'  ' NLK%0')  (' PRKCA%0'  ' SMAD7_g%0')  (' PRKCA%0'  ' SMAD6_g%0')  (' PRKCA%0'  ' AP1_c%0')  (' PRKCA%0'  ' ACVR1%0')  (' PRKCA%0'  ' PTPN6%0')  (' PRKCA%0'  ' CDC42%0')  (' PRKCA%0'  ' GRB2%0')  (' PRKCA%0'  ' TGFBR1%0')  (' PRKCA%0'  ' SMURF1%0')  (' PRKCA%0'  ' SMURF2%0')  (' PRKCA%0'  ' RHOA%0')  (' PRKCA%0'  ' BMPR2%0')  (' PRKCA%0'  ' PARD6A%0')  (' PRKCA%0'  ' DAAM1%0')  (' PRKCA%0'  ' SFRP1_g%0')  (' PRKCA%0'  ' PPM1A%0')  (' PRKCA%0'  ' CFL_f%0')  (' PRKCA%0'  ' PAK1%0')  (' PRKCA%0'  ' MAP3K11%0')  (' PRKCA%0'  ' MAP3K4%0')  (' PRKCA%0'  ' LIMK1%0')  (' PRKCA%0'  ' ROCK1%0')  (' PRKCA%0'  ' ITCH%0')  (' PRKCA%0'  ' ARHGAP24%0')  (' PRKCA%0'  ' TIAM1%0')  (' PRKCA%0'  ' RND3%0')  (' PRKCA%0'  ' MAPK8IP3%0')  (' PRKCA%0'  ' MXD1%0')  (' PRKCA%0'  ' PIP3%0')  (' VAV1%0'  ' SRC%0')  (' VAV1%0'  ' CSK%0')  (' VAV1%0'  ' CHUK%0')  (' VAV1%0'  ' RAC_f%0')  (' VAV1%0'  ' DUSP1%0')  (' VAV1%0'  ' TGFBR2%0')  (' VAV1%0'  ' ILR_f%0')  (' VAV1%0'  ' SYK%0')  (' VAV1%0'  ' IRAK1%0')  (' VAV1%0'  ' SHC1%0')  (' VAV1%0'  ' JAK_f%0')  (' VAV1%0'  ' CBPp300_c%0')  (' VAV1%0'  ' SKP2%0')  (' VAV1%0'  ' TP53%0')  (' VAV1%0'  ' SMAD7%0')  (' VAV1%0'  ' SMAD6%0')  (' VAV1%0'  ' DKK_f%0')  (' VAV1%0'  ' FOXO_f%0')  (' VAV1%0'  ' TCF7_f%0')  (' VAV1%0'  ' DKK_g%0')  (' VAV1%0'  ' MYC%0')  (' VAV1%0'  ' CCND1%0')  (' VAV1%0'  ' EGR1%0')  (' VAV1%0'  ' MMP_f%0')  (' VAV1%0'  ' PTEN_g%0')  (' VAV1%0'  ' RTPK_f%0')  (' VAV1%0'  ' CTNNB1%0')  (' VAV1%0'  'LEF1%0')  (' VAV1%0'  'SFRP1%0')  (' VAV1%0'  'FZD_f%0')  (' VAV1%0'  ' CASP8%0')  (' VAV1%0'  ' REL_f%0')  (' VAV1%0'  ' NFKB_f%0')  (' VAV1%0'  ' DVL_f%0')  (' VAV1%0'  ' LRP_f%0')  (' VAV1%0'  ' BTRC%0')  (' VAV1%0'  ' CK1_f%0')  (' VAV1%0'  ' AXIN1%0')  (' VAV1%0'  ' mTORC2_c%0')  (' VAV1%0'  ' PDPK1%0')  (' VAV1%0'  ' MEK_f%0')  (' VAV1%0'  ' CYCS%0')  (' VAV1%0'  ' CASP9%0')  (' VAV1%0'  ' GSK3_f%0')  (' VAV1%0'  ' IRS1%0')  (' VAV1%0'  ' MDM2%0')  (' VAV1%0'  ' AKT_f%0')  (' VAV1%0'  ' BCL2%0')  (' VAV1%0'  ' RAF_f%0')  (' VAV1%0'  ' mTORC1_c%0')  (' VAV1%0'  ' RHEB%0')  (' VAV1%0'  ' RTPK_g%0')  (' VAV1%0'  ' PTEN%0')  (' VAV1%0'  ' CASP3%0')  (' VAV1%0'  ' PIK3CA%0')  (' VAV1%0'  ' CREBBP%0')  (' VAV1%0'  ' PTPN11%0')  (' VAV1%0'  ' KRAS%0')  (' VAV1%0'  ' MAP2K4%0')  (' VAV1%0'  ' MAP2K7%0')  (' VAV1%0'  ' MAPK14%0')  (' VAV1%0'  ' JNK_f%0')  (' VAV1%0'  ' MAP2K3%0')  (' VAV1%0'  ' ERK_f%0')  (' VAV1%0'  ' LIF%0')  (' VAV1%0'  ' PPP1CA%0')  (' VAV1%0'  ' GAB_f%0')  (' VAV1%0'  ' SOS1%0')  (' VAV1%0'  ' PRKCA%0')  (' VAV1%0'  ' PLCG1%0')  (' VAV1%0'  ' PRKCD%0')  (' VAV1%0'  ' RSK_f%0')  (' VAV1%0'  ' S6K_f%0')  (' VAV1%0'  ' PLK1%0')  (' VAV1%0'  ' ILK%0')  (' VAV1%0'  ' SOCS1%0')  (' VAV1%0'  ' DUSP6%0')  (' VAV1%0'  ' STAT3%0')  (' VAV1%0'  ' LIMK2%0')  (' VAV1%0'  ' EP300%0')  (' VAV1%0'  ' STAT1%0')  (' VAV1%0'  ' IKBKB%0')  (' VAV1%0'  ' SRF%0')  (' VAV1%0'  ' PIAS1%0')  (' VAV1%0'  ' TRAF6%0')  (' VAV1%0'  ' SOCS1_g%0')  (' VAV1%0'  ' ISGF3_c%0')  (' VAV1%0'  ' STAT2%0')  (' VAV1%0'  ' CFLAR%0')  (' VAV1%0'  ' SMAD2%0')  (' VAV1%0'  ' MDM2_g%0')  (' VAV1%0'  ' BAX%0')  (' VAV1%0'  ' PRKACA%0')  (' VAV1%0'  ' TGFB1%0')  (' VAV1%0'  ' MAP3K8%0')  (' VAV1%0'  ' TSC_f%0')  (' VAV1%0'  ' SMAD4%0')  (' VAV1%0'  ' BAD%0')  (' VAV1%0'  ' MAP3K5%0')  (' VAV1%0'  ' AKT1S1%0')  (' VAV1%0'  ' SKI%0')  (' VAV1%0'  ' SMAD3%0')  (' VAV1%0'  ' MAPKAPK2%0')  (' VAV1%0'  ' DUSP1_g%0')  (' VAV1%0'  ' MSK_f%0')  (' VAV1%0'  ' GRAP2%0')  (' VAV1%0'  ' TAB_f%0')  (' VAV1%0'  ' ATF2%0')  (' VAV1%0'  ' SMAD5%0')  (' VAV1%0'  ' SMAD1%0')  (' VAV1%0'  ' FOS%0')  (' VAV1%0'  ' JUN%0')  (' VAV1%0'  ' MAP3K7%0')  (' VAV1%0'  ' NLK%0')  (' VAV1%0'  ' SMAD7_g%0')  (' VAV1%0'  ' SMAD6_g%0')  (' VAV1%0'  ' AP1_c%0')  (' VAV1%0'  ' ACVR1%0')  (' VAV1%0'  ' PTPN6%0')  (' VAV1%0'  ' CDC42%0')  (' VAV1%0'  ' GRB2%0')  (' VAV1%0'  ' TGFBR1%0')  (' VAV1%0'  ' SMURF1%0')  (' VAV1%0'  ' SMURF2%0')  (' VAV1%0'  ' RHOA%0')  (' VAV1%0'  ' BMPR2%0')  (' VAV1%0'  ' PARD6A%0')  (' VAV1%0'  ' DAAM1%0')  (' VAV1%0'  ' SFRP1_g%0')  (' VAV1%0'  ' PPM1A%0')  (' VAV1%0'  ' CFL_f%0')  (' VAV1%0'  ' PAK1%0')  (' VAV1%0'  ' MAP3K11%0')  (' VAV1%0'  ' MAP3K4%0')  (' VAV1%0'  ' LIMK1%0')  (' VAV1%0'  ' ROCK1%0')  (' VAV1%0'  ' ITCH%0')  (' VAV1%0'  ' ARHGAP24%0')  (' VAV1%0'  ' TIAM1%0')  (' VAV1%0'  ' RND3%0')  (' VAV1%0'  ' MAPK8IP3%0')  (' VAV1%0'  ' MXD1%0')  (' VAV1%0'  ' PIP3%0')  (' PLCG1%0'  ' SRC%0')  (' PLCG1%0'  ' CSK%0')  (' PLCG1%0'  ' CHUK%0')  (' PLCG1%0'  ' RAC_f%0')  (' PLCG1%0'  ' DUSP1%0')  (' PLCG1%0'  ' TGFBR2%0')  (' PLCG1%0'  ' ILR_f%0')  (' PLCG1%0'  ' SYK%0')  (' PLCG1%0'  ' IRAK1%0')  (' PLCG1%0'  ' SHC1%0')  (' PLCG1%0'  ' JAK_f%0')  (' PLCG1%0'  ' CBPp300_c%0')  (' PLCG1%0'  ' SKP2%0')  (' PLCG1%0'  ' TP53%0')  (' PLCG1%0'  ' SMAD7%0')  (' PLCG1%0'  ' SMAD6%0')  (' PLCG1%0'  ' DKK_f%0')  (' PLCG1%0'  ' FOXO_f%0')  (' PLCG1%0'  ' TCF7_f%0')  (' PLCG1%0'  ' DKK_g%0')  (' PLCG1%0'  ' MYC%0')  (' PLCG1%0'  ' CCND1%0')  (' PLCG1%0'  ' EGR1%0')  (' PLCG1%0'  ' MMP_f%0')  (' PLCG1%0'  ' PTEN_g%0')  (' PLCG1%0'  ' RTPK_f%0')  (' PLCG1%0'  ' CTNNB1%0')  (' PLCG1%0'  'LEF1%0')  (' PLCG1%0'  'SFRP1%0')  (' PLCG1%0'  'FZD_f%0')  (' PLCG1%0'  ' CASP8%0')  (' PLCG1%0'  ' REL_f%0')  (' PLCG1%0'  ' NFKB_f%0')  (' PLCG1%0'  ' DVL_f%0')  (' PLCG1%0'  ' LRP_f%0')  (' PLCG1%0'  ' BTRC%0')  (' PLCG1%0'  ' CK1_f%0')  (' PLCG1%0'  ' AXIN1%0')  (' PLCG1%0'  ' mTORC2_c%0')  (' PLCG1%0'  ' PDPK1%0')  (' PLCG1%0'  ' MEK_f%0')  (' PLCG1%0'  ' CYCS%0')  (' PLCG1%0'  ' CASP9%0')  (' PLCG1%0'  ' GSK3_f%0')  (' PLCG1%0'  ' IRS1%0')  (' PLCG1%0'  ' MDM2%0')  (' PLCG1%0'  ' AKT_f%0')  (' PLCG1%0'  ' BCL2%0')  (' PLCG1%0'  ' RAF_f%0')  (' PLCG1%0'  ' mTORC1_c%0')  (' PLCG1%0'  ' RHEB%0')  (' PLCG1%0'  ' RTPK_g%0')  (' PLCG1%0'  ' PTEN%0')  (' PLCG1%0'  ' CASP3%0')  (' PLCG1%0'  ' PIK3CA%0')  (' PLCG1%0'  ' CREBBP%0')  (' PLCG1%0'  ' PTPN11%0')  (' PLCG1%0'  ' KRAS%0')  (' PLCG1%0'  ' MAP2K4%0')  (' PLCG1%0'  ' MAP2K7%0')  (' PLCG1%0'  ' MAPK14%0')  (' PLCG1%0'  ' JNK_f%0')  (' PLCG1%0'  ' MAP2K3%0')  (' PLCG1%0'  ' ERK_f%0')  (' PLCG1%0'  ' LIF%0')  (' PLCG1%0'  ' PPP1CA%0')  (' PLCG1%0'  ' GAB_f%0')  (' PLCG1%0'  ' SOS1%0')  (' PLCG1%0'  ' PRKCA%0')  (' PLCG1%0'  ' VAV1%0')  (' PLCG1%0'  ' PRKCD%0')  (' PLCG1%0'  ' RSK_f%0')  (' PLCG1%0'  ' S6K_f%0')  (' PLCG1%0'  ' PLK1%0')  (' PLCG1%0'  ' ILK%0')  (' PLCG1%0'  ' SOCS1%0')  (' PLCG1%0'  ' DUSP6%0')  (' PLCG1%0'  ' STAT3%0')  (' PLCG1%0'  ' LIMK2%0')  (' PLCG1%0'  ' EP300%0')  (' PLCG1%0'  ' STAT1%0')  (' PLCG1%0'  ' IKBKB%0')  (' PLCG1%0'  ' SRF%0')  (' PLCG1%0'  ' PIAS1%0')  (' PLCG1%0'  ' TRAF6%0')  (' PLCG1%0'  ' SOCS1_g%0')  (' PLCG1%0'  ' ISGF3_c%0')  (' PLCG1%0'  ' STAT2%0')  (' PLCG1%0'  ' CFLAR%0')  (' PLCG1%0'  ' SMAD2%0')  (' PLCG1%0'  ' MDM2_g%0')  (' PLCG1%0'  ' BAX%0')  (' PLCG1%0'  ' PRKACA%0')  (' PLCG1%0'  ' TGFB1%0')  (' PLCG1%0'  ' MAP3K8%0')  (' PLCG1%0'  ' TSC_f%0')  (' PLCG1%0'  ' SMAD4%0')  (' PLCG1%0'  ' BAD%0')  (' PLCG1%0'  ' MAP3K5%0')  (' PLCG1%0'  ' AKT1S1%0')  (' PLCG1%0'  ' SKI%0')  (' PLCG1%0'  ' SMAD3%0')  (' PLCG1%0'  ' MAPKAPK2%0')  (' PLCG1%0'  ' DUSP1_g%0')  (' PLCG1%0'  ' MSK_f%0')  (' PLCG1%0'  ' GRAP2%0')  (' PLCG1%0'  ' TAB_f%0')  (' PLCG1%0'  ' ATF2%0')  (' PLCG1%0'  ' SMAD5%0')  (' PLCG1%0'  ' SMAD1%0')  (' PLCG1%0'  ' FOS%0')  (' PLCG1%0'  ' JUN%0')  (' PLCG1%0'  ' MAP3K7%0')  (' PLCG1%0'  ' NLK%0')  (' PLCG1%0'  ' SMAD7_g%0')  (' PLCG1%0'  ' SMAD6_g%0')  (' PLCG1%0'  ' AP1_c%0')  (' PLCG1%0'  ' ACVR1%0')  (' PLCG1%0'  ' PTPN6%0')  (' PLCG1%0'  ' CDC42%0')  (' PLCG1%0'  ' GRB2%0')  (' PLCG1%0'  ' TGFBR1%0')  (' PLCG1%0'  ' SMURF1%0')  (' PLCG1%0'  ' SMURF2%0')  (' PLCG1%0'  ' RHOA%0')  (' PLCG1%0'  ' BMPR2%0')  (' PLCG1%0'  ' PARD6A%0')  (' PLCG1%0'  ' DAAM1%0')  (' PLCG1%0'  ' SFRP1_g%0')  (' PLCG1%0'  ' PPM1A%0')  (' PLCG1%0'  ' CFL_f%0')  (' PLCG1%0'  ' PAK1%0')  (' PLCG1%0'  ' MAP3K11%0')  (' PLCG1%0'  ' MAP3K4%0')  (' PLCG1%0'  ' LIMK1%0')  (' PLCG1%0'  ' ROCK1%0')  (' PLCG1%0'  ' ITCH%0')  (' PLCG1%0'  ' ARHGAP24%0')  (' PLCG1%0'  ' TIAM1%0')  (' PLCG1%0'  ' RND3%0')  (' PLCG1%0'  ' MAPK8IP3%0')  (' PLCG1%0'  ' MXD1%0')  (' PLCG1%0'  ' PIP3%0')  (' PRKCD%0'  ' SRC%0')  (' PRKCD%0'  ' CSK%0')  (' PRKCD%0'  ' CHUK%0')  (' PRKCD%0'  ' RAC_f%0')  (' PRKCD%0'  ' DUSP1%0')  (' PRKCD%0'  ' TGFBR2%0')  (' PRKCD%0'  ' ILR_f%0')  (' PRKCD%0'  ' SYK%0')  (' PRKCD%0'  ' IRAK1%0')  (' PRKCD%0'  ' SHC1%0')  (' PRKCD%0'  ' JAK_f%0')  (' PRKCD%0'  ' CBPp300_c%0')  (' PRKCD%0'  ' SKP2%0')  (' PRKCD%0'  ' TP53%0')  (' PRKCD%0'  ' SMAD7%0')  (' PRKCD%0'  ' SMAD6%0')  (' PRKCD%0'  ' DKK_f%0')  (' PRKCD%0'  ' FOXO_f%0')  (' PRKCD%0'  ' TCF7_f%0')  (' PRKCD%0'  ' DKK_g%0')  (' PRKCD%0'  ' MYC%0')  (' PRKCD%0'  ' CCND1%0')  (' PRKCD%0'  ' EGR1%0')  (' PRKCD%0'  ' MMP_f%0')  (' PRKCD%0'  ' PTEN_g%0')  (' PRKCD%0'  ' RTPK_f%0')  (' PRKCD%0'  ' CTNNB1%0')  (' PRKCD%0'  'LEF1%0')  (' PRKCD%0'  'SFRP1%0')  (' PRKCD%0'  'FZD_f%0')  (' PRKCD%0'  ' CASP8%0')  (' PRKCD%0'  ' REL_f%0')  (' PRKCD%0'  ' NFKB_f%0')  (' PRKCD%0'  ' DVL_f%0')  (' PRKCD%0'  ' LRP_f%0')  (' PRKCD%0'  ' BTRC%0')  (' PRKCD%0'  ' CK1_f%0')  (' PRKCD%0'  ' AXIN1%0')  (' PRKCD%0'  ' mTORC2_c%0')  (' PRKCD%0'  ' PDPK1%0')  (' PRKCD%0'  ' MEK_f%0')  (' PRKCD%0'  ' CYCS%0')  (' PRKCD%0'  ' CASP9%0')  (' PRKCD%0'  ' GSK3_f%0')  (' PRKCD%0'  ' IRS1%0')  (' PRKCD%0'  ' MDM2%0')  (' PRKCD%0'  ' AKT_f%0')  (' PRKCD%0'  ' BCL2%0')  (' PRKCD%0'  ' RAF_f%0')  (' PRKCD%0'  ' mTORC1_c%0')  (' PRKCD%0'  ' RHEB%0')  (' PRKCD%0'  ' RTPK_g%0')  (' PRKCD%0'  ' PTEN%0')  (' PRKCD%0'  ' CASP3%0')  (' PRKCD%0'  ' PIK3CA%0')  (' PRKCD%0'  ' CREBBP%0')  (' PRKCD%0'  ' PTPN11%0')  (' PRKCD%0'  ' KRAS%0')  (' PRKCD%0'  ' MAP2K4%0')  (' PRKCD%0'  ' MAP2K7%0')  (' PRKCD%0'  ' MAPK14%0')  (' PRKCD%0'  ' JNK_f%0')  (' PRKCD%0'  ' MAP2K3%0')  (' PRKCD%0'  ' ERK_f%0')  (' PRKCD%0'  ' LIF%0')  (' PRKCD%0'  ' PPP1CA%0')  (' PRKCD%0'  ' GAB_f%0')  (' PRKCD%0'  ' SOS1%0')  (' PRKCD%0'  ' PRKCA%0')  (' PRKCD%0'  ' VAV1%0')  (' PRKCD%0'  ' PLCG1%0')  (' PRKCD%0'  ' RSK_f%0')  (' PRKCD%0'  ' S6K_f%0')  (' PRKCD%0'  ' PLK1%0')  (' PRKCD%0'  ' ILK%0')  (' PRKCD%0'  ' SOCS1%0')  (' PRKCD%0'  ' DUSP6%0')  (' PRKCD%0'  ' STAT3%0')  (' PRKCD%0'  ' LIMK2%0')  (' PRKCD%0'  ' EP300%0')  (' PRKCD%0'  ' STAT1%0')  (' PRKCD%0'  ' IKBKB%0')  (' PRKCD%0'  ' SRF%0')  (' PRKCD%0'  ' PIAS1%0')  (' PRKCD%0'  ' TRAF6%0')  (' PRKCD%0'  ' SOCS1_g%0')  (' PRKCD%0'  ' ISGF3_c%0')  (' PRKCD%0'  ' STAT2%0')  (' PRKCD%0'  ' CFLAR%0')  (' PRKCD%0'  ' SMAD2%0')  (' PRKCD%0'  ' MDM2_g%0')  (' PRKCD%0'  ' BAX%0')  (' PRKCD%0'  ' PRKACA%0')  (' PRKCD%0'  ' TGFB1%0')  (' PRKCD%0'  ' MAP3K8%0')  (' PRKCD%0'  ' TSC_f%0')  (' PRKCD%0'  ' SMAD4%0')  (' PRKCD%0'  ' BAD%0')  (' PRKCD%0'  ' MAP3K5%0')  (' PRKCD%0'  ' AKT1S1%0')  (' PRKCD%0'  ' SKI%0')  (' PRKCD%0'  ' SMAD3%0')  (' PRKCD%0'  ' MAPKAPK2%0')  (' PRKCD%0'  ' DUSP1_g%0')  (' PRKCD%0'  ' MSK_f%0')  (' PRKCD%0'  ' GRAP2%0')  (' PRKCD%0'  ' TAB_f%0')  (' PRKCD%0'  ' ATF2%0')  (' PRKCD%0'  ' SMAD5%0')  (' PRKCD%0'  ' SMAD1%0')  (' PRKCD%0'  ' FOS%0')  (' PRKCD%0'  ' JUN%0')  (' PRKCD%0'  ' MAP3K7%0')  (' PRKCD%0'  ' NLK%0')  (' PRKCD%0'  ' SMAD7_g%0')  (' PRKCD%0'  ' SMAD6_g%0')  (' PRKCD%0'  ' AP1_c%0')  (' PRKCD%0'  ' ACVR1%0')  (' PRKCD%0'  ' PTPN6%0')  (' PRKCD%0'  ' CDC42%0')  (' PRKCD%0'  ' GRB2%0')  (' PRKCD%0'  ' TGFBR1%0')  (' PRKCD%0'  ' SMURF1%0')  (' PRKCD%0'  ' SMURF2%0')  (' PRKCD%0'  ' RHOA%0')  (' PRKCD%0'  ' BMPR2%0')  (' PRKCD%0'  ' PARD6A%0')  (' PRKCD%0'  ' DAAM1%0')  (' PRKCD%0'  ' SFRP1_g%0')  (' PRKCD%0'  ' PPM1A%0')  (' PRKCD%0'  ' CFL_f%0')  (' PRKCD%0'  ' PAK1%0')  (' PRKCD%0'  ' MAP3K11%0')  (' PRKCD%0'  ' MAP3K4%0')  (' PRKCD%0'  ' LIMK1%0')  (' PRKCD%0'  ' ROCK1%0')  (' PRKCD%0'  ' ITCH%0')  (' PRKCD%0'  ' ARHGAP24%0')  (' PRKCD%0'  ' TIAM1%0')  (' PRKCD%0'  ' RND3%0')  (' PRKCD%0'  ' MAPK8IP3%0')  (' PRKCD%0'  ' MXD1%0')  (' PRKCD%0'  ' PIP3%0')  (' RSK_f%0'  ' SRC%0')  (' RSK_f%0'  ' CSK%0')  (' RSK_f%0'  ' CHUK%0')  (' RSK_f%0'  ' RAC_f%0')  (' RSK_f%0'  ' DUSP1%0')  (' RSK_f%0'  ' TGFBR2%0')  (' RSK_f%0'  ' ILR_f%0')  (' RSK_f%0'  ' SYK%0')  (' RSK_f%0'  ' IRAK1%0')  (' RSK_f%0'  ' SHC1%0')  (' RSK_f%0'  ' JAK_f%0')  (' RSK_f%0'  ' CBPp300_c%0')  (' RSK_f%0'  ' SKP2%0')  (' RSK_f%0'  ' TP53%0')  (' RSK_f%0'  ' SMAD7%0')  (' RSK_f%0'  ' SMAD6%0')  (' RSK_f%0'  ' DKK_f%0')  (' RSK_f%0'  ' FOXO_f%0')  (' RSK_f%0'  ' TCF7_f%0')  (' RSK_f%0'  ' DKK_g%0')  (' RSK_f%0'  ' MYC%0')  (' RSK_f%0'  ' CCND1%0')  (' RSK_f%0'  ' EGR1%0')  (' RSK_f%0'  ' MMP_f%0')  (' RSK_f%0'  ' PTEN_g%0')  (' RSK_f%0'  ' RTPK_f%0')  (' RSK_f%0'  ' CTNNB1%0')  (' RSK_f%0'  'LEF1%0')  (' RSK_f%0'  'SFRP1%0')  (' RSK_f%0'  'FZD_f%0')  (' RSK_f%0'  ' CASP8%0')  (' RSK_f%0'  ' REL_f%0')  (' RSK_f%0'  ' NFKB_f%0')  (' RSK_f%0'  ' DVL_f%0')  (' RSK_f%0'  ' LRP_f%0')  (' RSK_f%0'  ' BTRC%0')  (' RSK_f%0'  ' CK1_f%0')  (' RSK_f%0'  ' AXIN1%0')  (' RSK_f%0'  ' mTORC2_c%0')  (' RSK_f%0'  ' PDPK1%0')  (' RSK_f%0'  ' MEK_f%0')  (' RSK_f%0'  ' CYCS%0')  (' RSK_f%0'  ' CASP9%0')  (' RSK_f%0'  ' GSK3_f%0')  (' RSK_f%0'  ' IRS1%0')  (' RSK_f%0'  ' MDM2%0')  (' RSK_f%0'  ' AKT_f%0')  (' RSK_f%0'  ' BCL2%0')  (' RSK_f%0'  ' RAF_f%0')  (' RSK_f%0'  ' mTORC1_c%0')  (' RSK_f%0'  ' RHEB%0')  (' RSK_f%0'  ' RTPK_g%0')  (' RSK_f%0'  ' PTEN%0')  (' RSK_f%0'  ' CASP3%0')  (' RSK_f%0'  ' PIK3CA%0')  (' RSK_f%0'  ' CREBBP%0')  (' RSK_f%0'  ' PTPN11%0')  (' RSK_f%0'  ' KRAS%0')  (' RSK_f%0'  ' MAP2K4%0')  (' RSK_f%0'  ' MAP2K7%0')  (' RSK_f%0'  ' MAPK14%0')  (' RSK_f%0'  ' JNK_f%0')  (' RSK_f%0'  ' MAP2K3%0')  (' RSK_f%0'  ' ERK_f%0')  (' RSK_f%0'  ' LIF%0')  (' RSK_f%0'  ' PPP1CA%0')  (' RSK_f%0'  ' GAB_f%0')  (' RSK_f%0'  ' SOS1%0')  (' RSK_f%0'  ' PRKCA%0')  (' RSK_f%0'  ' VAV1%0')  (' RSK_f%0'  ' PLCG1%0')  (' RSK_f%0'  ' PRKCD%0')  (' RSK_f%0'  ' S6K_f%0')  (' RSK_f%0'  ' PLK1%0')  (' RSK_f%0'  ' ILK%0')  (' RSK_f%0'  ' SOCS1%0')  (' RSK_f%0'  ' DUSP6%0')  (' RSK_f%0'  ' STAT3%0')  (' RSK_f%0'  ' LIMK2%0')  (' RSK_f%0'  ' EP300%0')  (' RSK_f%0'  ' STAT1%0')  (' RSK_f%0'  ' IKBKB%0')  (' RSK_f%0'  ' SRF%0')  (' RSK_f%0'  ' PIAS1%0')  (' RSK_f%0'  ' TRAF6%0')  (' RSK_f%0'  ' SOCS1_g%0')  (' RSK_f%0'  ' ISGF3_c%0')  (' RSK_f%0'  ' STAT2%0')  (' RSK_f%0'  ' CFLAR%0')  (' RSK_f%0'  ' SMAD2%0')  (' RSK_f%0'  ' MDM2_g%0')  (' RSK_f%0'  ' BAX%0')  (' RSK_f%0'  ' PRKACA%0')  (' RSK_f%0'  ' TGFB1%0')  (' RSK_f%0'  ' MAP3K8%0')  (' RSK_f%0'  ' TSC_f%0')  (' RSK_f%0'  ' SMAD4%0')  (' RSK_f%0'  ' BAD%0')  (' RSK_f%0'  ' MAP3K5%0')  (' RSK_f%0'  ' AKT1S1%0')  (' RSK_f%0'  ' SKI%0')  (' RSK_f%0'  ' SMAD3%0')  (' RSK_f%0'  ' MAPKAPK2%0')  (' RSK_f%0'  ' DUSP1_g%0')  (' RSK_f%0'  ' MSK_f%0')  (' RSK_f%0'  ' GRAP2%0')  (' RSK_f%0'  ' TAB_f%0')  (' RSK_f%0'  ' ATF2%0')  (' RSK_f%0'  ' SMAD5%0')  (' RSK_f%0'  ' SMAD1%0')  (' RSK_f%0'  ' FOS%0')  (' RSK_f%0'  ' JUN%0')  (' RSK_f%0'  ' MAP3K7%0')  (' RSK_f%0'  ' NLK%0')  (' RSK_f%0'  ' SMAD7_g%0')  (' RSK_f%0'  ' SMAD6_g%0')  (' RSK_f%0'  ' AP1_c%0')  (' RSK_f%0'  ' ACVR1%0')  (' RSK_f%0'  ' PTPN6%0')  (' RSK_f%0'  ' CDC42%0')  (' RSK_f%0'  ' GRB2%0')  (' RSK_f%0'  ' TGFBR1%0')  (' RSK_f%0'  ' SMURF1%0')  (' RSK_f%0'  ' SMURF2%0')  (' RSK_f%0'  ' RHOA%0')  (' RSK_f%0'  ' BMPR2%0')  (' RSK_f%0'  ' PARD6A%0')  (' RSK_f%0'  ' DAAM1%0')  (' RSK_f%0'  ' SFRP1_g%0')  (' RSK_f%0'  ' PPM1A%0')  (' RSK_f%0'  ' CFL_f%0')  (' RSK_f%0'  ' PAK1%0')  (' RSK_f%0'  ' MAP3K11%0')  (' RSK_f%0'  ' MAP3K4%0')  (' RSK_f%0'  ' LIMK1%0')  (' RSK_f%0'  ' ROCK1%0')  (' RSK_f%0'  ' ITCH%0')  (' RSK_f%0'  ' ARHGAP24%0')  (' RSK_f%0'  ' TIAM1%0')  (' RSK_f%0'  ' RND3%0')  (' RSK_f%0'  ' MAPK8IP3%0')  (' RSK_f%0'  ' MXD1%0')  (' RSK_f%0'  ' PIP3%0')  (' S6K_f%0'  ' SRC%0')  (' S6K_f%0'  ' CSK%0')  (' S6K_f%0'  ' CHUK%0')  (' S6K_f%0'  ' RAC_f%0')  (' S6K_f%0'  ' DUSP1%0')  (' S6K_f%0'  ' TGFBR2%0')  (' S6K_f%0'  ' ILR_f%0')  (' S6K_f%0'  ' SYK%0')  (' S6K_f%0'  ' IRAK1%0')  (' S6K_f%0'  ' SHC1%0')  (' S6K_f%0'  ' JAK_f%0')  (' S6K_f%0'  ' CBPp300_c%0')  (' S6K_f%0'  ' SKP2%0')  (' S6K_f%0'  ' TP53%0')  (' S6K_f%0'  ' SMAD7%0')  (' S6K_f%0'  ' SMAD6%0')  (' S6K_f%0'  ' DKK_f%0')  (' S6K_f%0'  ' FOXO_f%0')  (' S6K_f%0'  ' TCF7_f%0')  (' S6K_f%0'  ' DKK_g%0')  (' S6K_f%0'  ' MYC%0')  (' S6K_f%0'  ' CCND1%0')  (' S6K_f%0'  ' EGR1%0')  (' S6K_f%0'  ' MMP_f%0')  (' S6K_f%0'  ' PTEN_g%0')  (' S6K_f%0'  ' RTPK_f%0')  (' S6K_f%0'  ' CTNNB1%0')  (' S6K_f%0'  'LEF1%0')  (' S6K_f%0'  'SFRP1%0')  (' S6K_f%0'  'FZD_f%0')  (' S6K_f%0'  ' CASP8%0')  (' S6K_f%0'  ' REL_f%0')  (' S6K_f%0'  ' NFKB_f%0')  (' S6K_f%0'  ' DVL_f%0')  (' S6K_f%0'  ' LRP_f%0')  (' S6K_f%0'  ' BTRC%0')  (' S6K_f%0'  ' CK1_f%0')  (' S6K_f%0'  ' AXIN1%0')  (' S6K_f%0'  ' mTORC2_c%0')  (' S6K_f%0'  ' PDPK1%0')  (' S6K_f%0'  ' MEK_f%0')  (' S6K_f%0'  ' CYCS%0')  (' S6K_f%0'  ' CASP9%0')  (' S6K_f%0'  ' GSK3_f%0')  (' S6K_f%0'  ' IRS1%0')  (' S6K_f%0'  ' MDM2%0')  (' S6K_f%0'  ' AKT_f%0')  (' S6K_f%0'  ' BCL2%0')  (' S6K_f%0'  ' RAF_f%0')  (' S6K_f%0'  ' mTORC1_c%0')  (' S6K_f%0'  ' RHEB%0')  (' S6K_f%0'  ' RTPK_g%0')  (' S6K_f%0'  ' PTEN%0')  (' S6K_f%0'  ' CASP3%0')  (' S6K_f%0'  ' PIK3CA%0')  (' S6K_f%0'  ' CREBBP%0')  (' S6K_f%0'  ' PTPN11%0')  (' S6K_f%0'  ' KRAS%0')  (' S6K_f%0'  ' MAP2K4%0')  (' S6K_f%0'  ' MAP2K7%0')  (' S6K_f%0'  ' MAPK14%0')  (' S6K_f%0'  ' JNK_f%0')  (' S6K_f%0'  ' MAP2K3%0')  (' S6K_f%0'  ' ERK_f%0')  (' S6K_f%0'  ' LIF%0')  (' S6K_f%0'  ' PPP1CA%0')  (' S6K_f%0'  ' GAB_f%0')  (' S6K_f%0'  ' SOS1%0')  (' S6K_f%0'  ' PRKCA%0')  (' S6K_f%0'  ' VAV1%0')  (' S6K_f%0'  ' PLCG1%0')  (' S6K_f%0'  ' PRKCD%0')  (' S6K_f%0'  ' RSK_f%0')  (' S6K_f%0'  ' PLK1%0')  (' S6K_f%0'  ' ILK%0')  (' S6K_f%0'  ' SOCS1%0')  (' S6K_f%0'  ' DUSP6%0')  (' S6K_f%0'  ' STAT3%0')  (' S6K_f%0'  ' LIMK2%0')  (' S6K_f%0'  ' EP300%0')  (' S6K_f%0'  ' STAT1%0')  (' S6K_f%0'  ' IKBKB%0')  (' S6K_f%0'  ' SRF%0')  (' S6K_f%0'  ' PIAS1%0')  (' S6K_f%0'  ' TRAF6%0')  (' S6K_f%0'  ' SOCS1_g%0')  (' S6K_f%0'  ' ISGF3_c%0')  (' S6K_f%0'  ' STAT2%0')  (' S6K_f%0'  ' CFLAR%0')  (' S6K_f%0'  ' SMAD2%0')  (' S6K_f%0'  ' MDM2_g%0')  (' S6K_f%0'  ' BAX%0')  (' S6K_f%0'  ' PRKACA%0')  (' S6K_f%0'  ' TGFB1%0')  (' S6K_f%0'  ' MAP3K8%0')  (' S6K_f%0'  ' TSC_f%0')  (' S6K_f%0'  ' SMAD4%0')  (' S6K_f%0'  ' BAD%0')  (' S6K_f%0'  ' MAP3K5%0')  (' S6K_f%0'  ' AKT1S1%0')  (' S6K_f%0'  ' SKI%0')  (' S6K_f%0'  ' SMAD3%0')  (' S6K_f%0'  ' MAPKAPK2%0')  (' S6K_f%0'  ' DUSP1_g%0')  (' S6K_f%0'  ' MSK_f%0')  (' S6K_f%0'  ' GRAP2%0')  (' S6K_f%0'  ' TAB_f%0')  (' S6K_f%0'  ' ATF2%0')  (' S6K_f%0'  ' SMAD5%0')  (' S6K_f%0'  ' SMAD1%0')  (' S6K_f%0'  ' FOS%0')  (' S6K_f%0'  ' JUN%0')  (' S6K_f%0'  ' MAP3K7%0')  (' S6K_f%0'  ' NLK%0')  (' S6K_f%0'  ' SMAD7_g%0')  (' S6K_f%0'  ' SMAD6_g%0')  (' S6K_f%0'  ' AP1_c%0')  (' S6K_f%0'  ' ACVR1%0')  (' S6K_f%0'  ' PTPN6%0')  (' S6K_f%0'  ' CDC42%0')  (' S6K_f%0'  ' GRB2%0')  (' S6K_f%0'  ' TGFBR1%0')  (' S6K_f%0'  ' SMURF1%0')  (' S6K_f%0'  ' SMURF2%0')  (' S6K_f%0'  ' RHOA%0')  (' S6K_f%0'  ' BMPR2%0')  (' S6K_f%0'  ' PARD6A%0')  (' S6K_f%0'  ' DAAM1%0')  (' S6K_f%0'  ' SFRP1_g%0')  (' S6K_f%0'  ' PPM1A%0')  (' S6K_f%0'  ' CFL_f%0')  (' S6K_f%0'  ' PAK1%0')  (' S6K_f%0'  ' MAP3K11%0')  (' S6K_f%0'  ' MAP3K4%0')  (' S6K_f%0'  ' LIMK1%0')  (' S6K_f%0'  ' ROCK1%0')  (' S6K_f%0'  ' ITCH%0')  (' S6K_f%0'  ' ARHGAP24%0')  (' S6K_f%0'  ' TIAM1%0')  (' S6K_f%0'  ' RND3%0')  (' S6K_f%0'  ' MAPK8IP3%0')  (' S6K_f%0'  ' MXD1%0')  (' S6K_f%0'  ' PIP3%0')  (' PLK1%0'  ' SRC%0')  (' PLK1%0'  ' CSK%0')  (' PLK1%0'  ' CHUK%0')  (' PLK1%0'  ' RAC_f%0')  (' PLK1%0'  ' DUSP1%0')  (' PLK1%0'  ' TGFBR2%0')  (' PLK1%0'  ' ILR_f%0')  (' PLK1%0'  ' SYK%0')  (' PLK1%0'  ' IRAK1%0')  (' PLK1%0'  ' SHC1%0')  (' PLK1%0'  ' JAK_f%0')  (' PLK1%0'  ' CBPp300_c%0')  (' PLK1%0'  ' SKP2%0')  (' PLK1%0'  ' TP53%0')  (' PLK1%0'  ' SMAD7%0')  (' PLK1%0'  ' SMAD6%0')  (' PLK1%0'  ' DKK_f%0')  (' PLK1%0'  ' FOXO_f%0')  (' PLK1%0'  ' TCF7_f%0')  (' PLK1%0'  ' DKK_g%0')  (' PLK1%0'  ' MYC%0')  (' PLK1%0'  ' CCND1%0')  (' PLK1%0'  ' EGR1%0')  (' PLK1%0'  ' MMP_f%0')  (' PLK1%0'  ' PTEN_g%0')  (' PLK1%0'  ' RTPK_f%0')  (' PLK1%0'  ' CTNNB1%0')  (' PLK1%0'  'LEF1%0')  (' PLK1%0'  'SFRP1%0')  (' PLK1%0'  'FZD_f%0')  (' PLK1%0'  ' CASP8%0')  (' PLK1%0'  ' REL_f%0')  (' PLK1%0'  ' NFKB_f%0')  (' PLK1%0'  ' DVL_f%0')  (' PLK1%0'  ' LRP_f%0')  (' PLK1%0'  ' BTRC%0')  (' PLK1%0'  ' CK1_f%0')  (' PLK1%0'  ' AXIN1%0')  (' PLK1%0'  ' mTORC2_c%0')  (' PLK1%0'  ' PDPK1%0')  (' PLK1%0'  ' MEK_f%0')  (' PLK1%0'  ' CYCS%0')  (' PLK1%0'  ' CASP9%0')  (' PLK1%0'  ' GSK3_f%0')  (' PLK1%0'  ' IRS1%0')  (' PLK1%0'  ' MDM2%0')  (' PLK1%0'  ' AKT_f%0')  (' PLK1%0'  ' BCL2%0')  (' PLK1%0'  ' RAF_f%0')  (' PLK1%0'  ' mTORC1_c%0')  (' PLK1%0'  ' RHEB%0')  (' PLK1%0'  ' RTPK_g%0')  (' PLK1%0'  ' PTEN%0')  (' PLK1%0'  ' CASP3%0')  (' PLK1%0'  ' PIK3CA%0')  (' PLK1%0'  ' CREBBP%0')  (' PLK1%0'  ' PTPN11%0')  (' PLK1%0'  ' KRAS%0')  (' PLK1%0'  ' MAP2K4%0')  (' PLK1%0'  ' MAP2K7%0')  (' PLK1%0'  ' MAPK14%0')  (' PLK1%0'  ' JNK_f%0')  (' PLK1%0'  ' MAP2K3%0')  (' PLK1%0'  ' ERK_f%0')  (' PLK1%0'  ' LIF%0')  (' PLK1%0'  ' PPP1CA%0')  (' PLK1%0'  ' GAB_f%0')  (' PLK1%0'  ' SOS1%0')  (' PLK1%0'  ' PRKCA%0')  (' PLK1%0'  ' VAV1%0')  (' PLK1%0'  ' PLCG1%0')  (' PLK1%0'  ' PRKCD%0')  (' PLK1%0'  ' RSK_f%0')  (' PLK1%0'  ' S6K_f%0')  (' PLK1%0'  ' ILK%0')  (' PLK1%0'  ' SOCS1%0')  (' PLK1%0'  ' DUSP6%0')  (' PLK1%0'  ' STAT3%0')  (' PLK1%0'  ' LIMK2%0')  (' PLK1%0'  ' EP300%0')  (' PLK1%0'  ' STAT1%0')  (' PLK1%0'  ' IKBKB%0')  (' PLK1%0'  ' SRF%0')  (' PLK1%0'  ' PIAS1%0')  (' PLK1%0'  ' TRAF6%0')  (' PLK1%0'  ' SOCS1_g%0')  (' PLK1%0'  ' ISGF3_c%0')  (' PLK1%0'  ' STAT2%0')  (' PLK1%0'  ' CFLAR%0')  (' PLK1%0'  ' SMAD2%0')  (' PLK1%0'  ' MDM2_g%0')  (' PLK1%0'  ' BAX%0')  (' PLK1%0'  ' PRKACA%0')  (' PLK1%0'  ' TGFB1%0')  (' PLK1%0'  ' MAP3K8%0')  (' PLK1%0'  ' TSC_f%0')  (' PLK1%0'  ' SMAD4%0')  (' PLK1%0'  ' BAD%0')  (' PLK1%0'  ' MAP3K5%0')  (' PLK1%0'  ' AKT1S1%0')  (' PLK1%0'  ' SKI%0')  (' PLK1%0'  ' SMAD3%0')  (' PLK1%0'  ' MAPKAPK2%0')  (' PLK1%0'  ' DUSP1_g%0')  (' PLK1%0'  ' MSK_f%0')  (' PLK1%0'  ' GRAP2%0')  (' PLK1%0'  ' TAB_f%0')  (' PLK1%0'  ' ATF2%0')  (' PLK1%0'  ' SMAD5%0')  (' PLK1%0'  ' SMAD1%0')  (' PLK1%0'  ' FOS%0')  (' PLK1%0'  ' JUN%0')  (' PLK1%0'  ' MAP3K7%0')  (' PLK1%0'  ' NLK%0')  (' PLK1%0'  ' SMAD7_g%0')  (' PLK1%0'  ' SMAD6_g%0')  (' PLK1%0'  ' AP1_c%0')  (' PLK1%0'  ' ACVR1%0')  (' PLK1%0'  ' PTPN6%0')  (' PLK1%0'  ' CDC42%0')  (' PLK1%0'  ' GRB2%0')  (' PLK1%0'  ' TGFBR1%0')  (' PLK1%0'  ' SMURF1%0')  (' PLK1%0'  ' SMURF2%0')  (' PLK1%0'  ' RHOA%0')  (' PLK1%0'  ' BMPR2%0')  (' PLK1%0'  ' PARD6A%0')  (' PLK1%0'  ' DAAM1%0')  (' PLK1%0'  ' SFRP1_g%0')  (' PLK1%0'  ' PPM1A%0')  (' PLK1%0'  ' CFL_f%0')  (' PLK1%0'  ' PAK1%0')  (' PLK1%0'  ' MAP3K11%0')  (' PLK1%0'  ' MAP3K4%0')  (' PLK1%0'  ' LIMK1%0')  (' PLK1%0'  ' ROCK1%0')  (' PLK1%0'  ' ITCH%0')  (' PLK1%0'  ' ARHGAP24%0')  (' PLK1%0'  ' TIAM1%0')  (' PLK1%0'  ' RND3%0')  (' PLK1%0'  ' MAPK8IP3%0')  (' PLK1%0'  ' MXD1%0')  (' PLK1%0'  ' PIP3%0')  (' ILK%0'  ' SRC%0')  (' ILK%0'  ' CSK%0')  (' ILK%0'  ' CHUK%0')  (' ILK%0'  ' RAC_f%0')  (' ILK%0'  ' DUSP1%0')  (' ILK%0'  ' TGFBR2%0')  (' ILK%0'  ' ILR_f%0')  (' ILK%0'  ' SYK%0')  (' ILK%0'  ' IRAK1%0')  (' ILK%0'  ' SHC1%0')  (' ILK%0'  ' JAK_f%0')  (' ILK%0'  ' CBPp300_c%0')  (' ILK%0'  ' SKP2%0')  (' ILK%0'  ' TP53%0')  (' ILK%0'  ' SMAD7%0')  (' ILK%0'  ' SMAD6%0')  (' ILK%0'  ' DKK_f%0')  (' ILK%0'  ' FOXO_f%0')  (' ILK%0'  ' TCF7_f%0')  (' ILK%0'  ' DKK_g%0')  (' ILK%0'  ' MYC%0')  (' ILK%0'  ' CCND1%0')  (' ILK%0'  ' EGR1%0')  (' ILK%0'  ' MMP_f%0')  (' ILK%0'  ' PTEN_g%0')  (' ILK%0'  ' RTPK_f%0')  (' ILK%0'  ' CTNNB1%0')  (' ILK%0'  'LEF1%0')  (' ILK%0'  'SFRP1%0')  (' ILK%0'  'FZD_f%0')  (' ILK%0'  ' CASP8%0')  (' ILK%0'  ' REL_f%0')  (' ILK%0'  ' NFKB_f%0')  (' ILK%0'  ' DVL_f%0')  (' ILK%0'  ' LRP_f%0')  (' ILK%0'  ' BTRC%0')  (' ILK%0'  ' CK1_f%0')  (' ILK%0'  ' AXIN1%0')  (' ILK%0'  ' mTORC2_c%0')  (' ILK%0'  ' PDPK1%0')  (' ILK%0'  ' MEK_f%0')  (' ILK%0'  ' CYCS%0')  (' ILK%0'  ' CASP9%0')  (' ILK%0'  ' GSK3_f%0')  (' ILK%0'  ' IRS1%0')  (' ILK%0'  ' MDM2%0')  (' ILK%0'  ' AKT_f%0')  (' ILK%0'  ' BCL2%0')  (' ILK%0'  ' RAF_f%0')  (' ILK%0'  ' mTORC1_c%0')  (' ILK%0'  ' RHEB%0')  (' ILK%0'  ' RTPK_g%0')  (' ILK%0'  ' PTEN%0')  (' ILK%0'  ' CASP3%0')  (' ILK%0'  ' PIK3CA%0')  (' ILK%0'  ' CREBBP%0')  (' ILK%0'  ' PTPN11%0')  (' ILK%0'  ' KRAS%0')  (' ILK%0'  ' MAP2K4%0')  (' ILK%0'  ' MAP2K7%0')  (' ILK%0'  ' MAPK14%0')  (' ILK%0'  ' JNK_f%0')  (' ILK%0'  ' MAP2K3%0')  (' ILK%0'  ' ERK_f%0')  (' ILK%0'  ' LIF%0')  (' ILK%0'  ' PPP1CA%0')  (' ILK%0'  ' GAB_f%0')  (' ILK%0'  ' SOS1%0')  (' ILK%0'  ' PRKCA%0')  (' ILK%0'  ' VAV1%0')  (' ILK%0'  ' PLCG1%0')  (' ILK%0'  ' PRKCD%0')  (' ILK%0'  ' RSK_f%0')  (' ILK%0'  ' S6K_f%0')  (' ILK%0'  ' PLK1%0')  (' ILK%0'  ' SOCS1%0')  (' ILK%0'  ' DUSP6%0')  (' ILK%0'  ' STAT3%0')  (' ILK%0'  ' LIMK2%0')  (' ILK%0'  ' EP300%0')  (' ILK%0'  ' STAT1%0')  (' ILK%0'  ' IKBKB%0')  (' ILK%0'  ' SRF%0')  (' ILK%0'  ' PIAS1%0')  (' ILK%0'  ' TRAF6%0')  (' ILK%0'  ' SOCS1_g%0')  (' ILK%0'  ' ISGF3_c%0')  (' ILK%0'  ' STAT2%0')  (' ILK%0'  ' CFLAR%0')  (' ILK%0'  ' SMAD2%0')  (' ILK%0'  ' MDM2_g%0')  (' ILK%0'  ' BAX%0')  (' ILK%0'  ' PRKACA%0')  (' ILK%0'  ' TGFB1%0')  (' ILK%0'  ' MAP3K8%0')  (' ILK%0'  ' TSC_f%0')  (' ILK%0'  ' SMAD4%0')  (' ILK%0'  ' BAD%0')  (' ILK%0'  ' MAP3K5%0')  (' ILK%0'  ' AKT1S1%0')  (' ILK%0'  ' SKI%0')  (' ILK%0'  ' SMAD3%0')  (' ILK%0'  ' MAPKAPK2%0')  (' ILK%0'  ' DUSP1_g%0')  (' ILK%0'  ' MSK_f%0')  (' ILK%0'  ' GRAP2%0')  (' ILK%0'  ' TAB_f%0')  (' ILK%0'  ' ATF2%0')  (' ILK%0'  ' SMAD5%0')  (' ILK%0'  ' SMAD1%0')  (' ILK%0'  ' FOS%0')  (' ILK%0'  ' JUN%0')  (' ILK%0'  ' MAP3K7%0')  (' ILK%0'  ' NLK%0')  (' ILK%0'  ' SMAD7_g%0')  (' ILK%0'  ' SMAD6_g%0')  (' ILK%0'  ' AP1_c%0')  (' ILK%0'  ' ACVR1%0')  (' ILK%0'  ' PTPN6%0')  (' ILK%0'  ' CDC42%0')  (' ILK%0'  ' GRB2%0')  (' ILK%0'  ' TGFBR1%0')  (' ILK%0'  ' SMURF1%0')  (' ILK%0'  ' SMURF2%0')  (' ILK%0'  ' RHOA%0')  (' ILK%0'  ' BMPR2%0')  (' ILK%0'  ' PARD6A%0')  (' ILK%0'  ' DAAM1%0')  (' ILK%0'  ' SFRP1_g%0')  (' ILK%0'  ' PPM1A%0')  (' ILK%0'  ' CFL_f%0')  (' ILK%0'  ' PAK1%0')  (' ILK%0'  ' MAP3K11%0')  (' ILK%0'  ' MAP3K4%0')  (' ILK%0'  ' LIMK1%0')  (' ILK%0'  ' ROCK1%0')  (' ILK%0'  ' ITCH%0')  (' ILK%0'  ' ARHGAP24%0')  (' ILK%0'  ' TIAM1%0')  (' ILK%0'  ' RND3%0')  (' ILK%0'  ' MAPK8IP3%0')  (' ILK%0'  ' MXD1%0')  (' ILK%0'  ' PIP3%0')  (' SOCS1%0'  ' SRC%0')  (' SOCS1%0'  ' CSK%0')  (' SOCS1%0'  ' CHUK%0')  (' SOCS1%0'  ' RAC_f%0')  (' SOCS1%0'  ' DUSP1%0')  (' SOCS1%0'  ' TGFBR2%0')  (' SOCS1%0'  ' ILR_f%0')  (' SOCS1%0'  ' SYK%0')  (' SOCS1%0'  ' IRAK1%0')  (' SOCS1%0'  ' SHC1%0')  (' SOCS1%0'  ' JAK_f%0')  (' SOCS1%0'  ' CBPp300_c%0')  (' SOCS1%0'  ' SKP2%0')  (' SOCS1%0'  ' TP53%0')  (' SOCS1%0'  ' SMAD7%0')  (' SOCS1%0'  ' SMAD6%0')  (' SOCS1%0'  ' DKK_f%0')  (' SOCS1%0'  ' FOXO_f%0')  (' SOCS1%0'  ' TCF7_f%0')  (' SOCS1%0'  ' DKK_g%0')  (' SOCS1%0'  ' MYC%0')  (' SOCS1%0'  ' CCND1%0')  (' SOCS1%0'  ' EGR1%0')  (' SOCS1%0'  ' MMP_f%0')  (' SOCS1%0'  ' PTEN_g%0')  (' SOCS1%0'  ' RTPK_f%0')  (' SOCS1%0'  ' CTNNB1%0')  (' SOCS1%0'  'LEF1%0')  (' SOCS1%0'  'SFRP1%0')  (' SOCS1%0'  'FZD_f%0')  (' SOCS1%0'  ' CASP8%0')  (' SOCS1%0'  ' REL_f%0')  (' SOCS1%0'  ' NFKB_f%0')  (' SOCS1%0'  ' DVL_f%0')  (' SOCS1%0'  ' LRP_f%0')  (' SOCS1%0'  ' BTRC%0')  (' SOCS1%0'  ' CK1_f%0')  (' SOCS1%0'  ' AXIN1%0')  (' SOCS1%0'  ' mTORC2_c%0')  (' SOCS1%0'  ' PDPK1%0')  (' SOCS1%0'  ' MEK_f%0')  (' SOCS1%0'  ' CYCS%0')  (' SOCS1%0'  ' CASP9%0')  (' SOCS1%0'  ' GSK3_f%0')  (' SOCS1%0'  ' IRS1%0')  (' SOCS1%0'  ' MDM2%0')  (' SOCS1%0'  ' AKT_f%0')  (' SOCS1%0'  ' BCL2%0')  (' SOCS1%0'  ' RAF_f%0')  (' SOCS1%0'  ' mTORC1_c%0')  (' SOCS1%0'  ' RHEB%0')  (' SOCS1%0'  ' RTPK_g%0')  (' SOCS1%0'  ' PTEN%0')  (' SOCS1%0'  ' CASP3%0')  (' SOCS1%0'  ' PIK3CA%0')  (' SOCS1%0'  ' CREBBP%0')  (' SOCS1%0'  ' PTPN11%0')  (' SOCS1%0'  ' KRAS%0')  (' SOCS1%0'  ' MAP2K4%0')  (' SOCS1%0'  ' MAP2K7%0')  (' SOCS1%0'  ' MAPK14%0')  (' SOCS1%0'  ' JNK_f%0')  (' SOCS1%0'  ' MAP2K3%0')  (' SOCS1%0'  ' ERK_f%0')  (' SOCS1%0'  ' LIF%0')  (' SOCS1%0'  ' PPP1CA%0')  (' SOCS1%0'  ' GAB_f%0')  (' SOCS1%0'  ' SOS1%0')  (' SOCS1%0'  ' PRKCA%0')  (' SOCS1%0'  ' VAV1%0')  (' SOCS1%0'  ' PLCG1%0')  (' SOCS1%0'  ' PRKCD%0')  (' SOCS1%0'  ' RSK_f%0')  (' SOCS1%0'  ' S6K_f%0')  (' SOCS1%0'  ' PLK1%0')  (' SOCS1%0'  ' ILK%0')  (' SOCS1%0'  ' DUSP6%0')  (' SOCS1%0'  ' STAT3%0')  (' SOCS1%0'  ' LIMK2%0')  (' SOCS1%0'  ' EP300%0')  (' SOCS1%0'  ' STAT1%0')  (' SOCS1%0'  ' IKBKB%0')  (' SOCS1%0'  ' SRF%0')  (' SOCS1%0'  ' PIAS1%0')  (' SOCS1%0'  ' TRAF6%0')  (' SOCS1%0'  ' SOCS1_g%0')  (' SOCS1%0'  ' ISGF3_c%0')  (' SOCS1%0'  ' STAT2%0')  (' SOCS1%0'  ' CFLAR%0')  (' SOCS1%0'  ' SMAD2%0')  (' SOCS1%0'  ' MDM2_g%0')  (' SOCS1%0'  ' BAX%0')  (' SOCS1%0'  ' PRKACA%0')  (' SOCS1%0'  ' TGFB1%0')  (' SOCS1%0'  ' MAP3K8%0')  (' SOCS1%0'  ' TSC_f%0')  (' SOCS1%0'  ' SMAD4%0')  (' SOCS1%0'  ' BAD%0')  (' SOCS1%0'  ' MAP3K5%0')  (' SOCS1%0'  ' AKT1S1%0')  (' SOCS1%0'  ' SKI%0')  (' SOCS1%0'  ' SMAD3%0')  (' SOCS1%0'  ' MAPKAPK2%0')  (' SOCS1%0'  ' DUSP1_g%0')  (' SOCS1%0'  ' MSK_f%0')  (' SOCS1%0'  ' GRAP2%0')  (' SOCS1%0'  ' TAB_f%0')  (' SOCS1%0'  ' ATF2%0')  (' SOCS1%0'  ' SMAD5%0')  (' SOCS1%0'  ' SMAD1%0')  (' SOCS1%0'  ' FOS%0')  (' SOCS1%0'  ' JUN%0')  (' SOCS1%0'  ' MAP3K7%0')  (' SOCS1%0'  ' NLK%0')  (' SOCS1%0'  ' SMAD7_g%0')  (' SOCS1%0'  ' SMAD6_g%0')  (' SOCS1%0'  ' AP1_c%0')  (' SOCS1%0'  ' ACVR1%0')  (' SOCS1%0'  ' PTPN6%0')  (' SOCS1%0'  ' CDC42%0')  (' SOCS1%0'  ' GRB2%0')  (' SOCS1%0'  ' TGFBR1%0')  (' SOCS1%0'  ' SMURF1%0')  (' SOCS1%0'  ' SMURF2%0')  (' SOCS1%0'  ' RHOA%0')  (' SOCS1%0'  ' BMPR2%0')  (' SOCS1%0'  ' PARD6A%0')  (' SOCS1%0'  ' DAAM1%0')  (' SOCS1%0'  ' SFRP1_g%0')  (' SOCS1%0'  ' PPM1A%0')  (' SOCS1%0'  ' CFL_f%0')  (' SOCS1%0'  ' PAK1%0')  (' SOCS1%0'  ' MAP3K11%0')  (' SOCS1%0'  ' MAP3K4%0')  (' SOCS1%0'  ' LIMK1%0')  (' SOCS1%0'  ' ROCK1%0')  (' SOCS1%0'  ' ITCH%0')  (' SOCS1%0'  ' ARHGAP24%0')  (' SOCS1%0'  ' TIAM1%0')  (' SOCS1%0'  ' RND3%0')  (' SOCS1%0'  ' MAPK8IP3%0')  (' SOCS1%0'  ' MXD1%0')  (' SOCS1%0'  ' PIP3%0')  (' DUSP6%0'  ' SRC%0')  (' DUSP6%0'  ' CSK%0')  (' DUSP6%0'  ' CHUK%0')  (' DUSP6%0'  ' RAC_f%0')  (' DUSP6%0'  ' DUSP1%0')  (' DUSP6%0'  ' TGFBR2%0')  (' DUSP6%0'  ' ILR_f%0')  (' DUSP6%0'  ' SYK%0')  (' DUSP6%0'  ' IRAK1%0')  (' DUSP6%0'  ' SHC1%0')  (' DUSP6%0'  ' JAK_f%0')  (' DUSP6%0'  ' CBPp300_c%0')  (' DUSP6%0'  ' SKP2%0')  (' DUSP6%0'  ' TP53%0')  (' DUSP6%0'  ' SMAD7%0')  (' DUSP6%0'  ' SMAD6%0')  (' DUSP6%0'  ' DKK_f%0')  (' DUSP6%0'  ' FOXO_f%0')  (' DUSP6%0'  ' TCF7_f%0')  (' DUSP6%0'  ' DKK_g%0')  (' DUSP6%0'  ' MYC%0')  (' DUSP6%0'  ' CCND1%0')  (' DUSP6%0'  ' EGR1%0')  (' DUSP6%0'  ' MMP_f%0')  (' DUSP6%0'  ' PTEN_g%0')  (' DUSP6%0'  ' RTPK_f%0')  (' DUSP6%0'  ' CTNNB1%0')  (' DUSP6%0'  'LEF1%0')  (' DUSP6%0'  'SFRP1%0')  (' DUSP6%0'  'FZD_f%0')  (' DUSP6%0'  ' CASP8%0')  (' DUSP6%0'  ' REL_f%0')  (' DUSP6%0'  ' NFKB_f%0')  (' DUSP6%0'  ' DVL_f%0')  (' DUSP6%0'  ' LRP_f%0')  (' DUSP6%0'  ' BTRC%0')  (' DUSP6%0'  ' CK1_f%0')  (' DUSP6%0'  ' AXIN1%0')  (' DUSP6%0'  ' mTORC2_c%0')  (' DUSP6%0'  ' PDPK1%0')  (' DUSP6%0'  ' MEK_f%0')  (' DUSP6%0'  ' CYCS%0')  (' DUSP6%0'  ' CASP9%0')  (' DUSP6%0'  ' GSK3_f%0')  (' DUSP6%0'  ' IRS1%0')  (' DUSP6%0'  ' MDM2%0')  (' DUSP6%0'  ' AKT_f%0')  (' DUSP6%0'  ' BCL2%0')  (' DUSP6%0'  ' RAF_f%0')  (' DUSP6%0'  ' mTORC1_c%0')  (' DUSP6%0'  ' RHEB%0')  (' DUSP6%0'  ' RTPK_g%0')  (' DUSP6%0'  ' PTEN%0')  (' DUSP6%0'  ' CASP3%0')  (' DUSP6%0'  ' PIK3CA%0')  (' DUSP6%0'  ' CREBBP%0')  (' DUSP6%0'  ' PTPN11%0')  (' DUSP6%0'  ' KRAS%0')  (' DUSP6%0'  ' MAP2K4%0')  (' DUSP6%0'  ' MAP2K7%0')  (' DUSP6%0'  ' MAPK14%0')  (' DUSP6%0'  ' JNK_f%0')  (' DUSP6%0'  ' MAP2K3%0')  (' DUSP6%0'  ' ERK_f%0')  (' DUSP6%0'  ' LIF%0')  (' DUSP6%0'  ' PPP1CA%0')  (' DUSP6%0'  ' GAB_f%0')  (' DUSP6%0'  ' SOS1%0')  (' DUSP6%0'  ' PRKCA%0')  (' DUSP6%0'  ' VAV1%0')  (' DUSP6%0'  ' PLCG1%0')  (' DUSP6%0'  ' PRKCD%0')  (' DUSP6%0'  ' RSK_f%0')  (' DUSP6%0'  ' S6K_f%0')  (' DUSP6%0'  ' PLK1%0')  (' DUSP6%0'  ' ILK%0')  (' DUSP6%0'  ' SOCS1%0')  (' DUSP6%0'  ' STAT3%0')  (' DUSP6%0'  ' LIMK2%0')  (' DUSP6%0'  ' EP300%0')  (' DUSP6%0'  ' STAT1%0')  (' DUSP6%0'  ' IKBKB%0')  (' DUSP6%0'  ' SRF%0')  (' DUSP6%0'  ' PIAS1%0')  (' DUSP6%0'  ' TRAF6%0')  (' DUSP6%0'  ' SOCS1_g%0')  (' DUSP6%0'  ' ISGF3_c%0')  (' DUSP6%0'  ' STAT2%0')  (' DUSP6%0'  ' CFLAR%0')  (' DUSP6%0'  ' SMAD2%0')  (' DUSP6%0'  ' MDM2_g%0')  (' DUSP6%0'  ' BAX%0')  (' DUSP6%0'  ' PRKACA%0')  (' DUSP6%0'  ' TGFB1%0')  (' DUSP6%0'  ' MAP3K8%0')  (' DUSP6%0'  ' TSC_f%0')  (' DUSP6%0'  ' SMAD4%0')  (' DUSP6%0'  ' BAD%0')  (' DUSP6%0'  ' MAP3K5%0')  (' DUSP6%0'  ' AKT1S1%0')  (' DUSP6%0'  ' SKI%0')  (' DUSP6%0'  ' SMAD3%0')  (' DUSP6%0'  ' MAPKAPK2%0')  (' DUSP6%0'  ' DUSP1_g%0')  (' DUSP6%0'  ' MSK_f%0')  (' DUSP6%0'  ' GRAP2%0')  (' DUSP6%0'  ' TAB_f%0')  (' DUSP6%0'  ' ATF2%0')  (' DUSP6%0'  ' SMAD5%0')  (' DUSP6%0'  ' SMAD1%0')  (' DUSP6%0'  ' FOS%0')  (' DUSP6%0'  ' JUN%0')  (' DUSP6%0'  ' MAP3K7%0')  (' DUSP6%0'  ' NLK%0')  (' DUSP6%0'  ' SMAD7_g%0')  (' DUSP6%0'  ' SMAD6_g%0')  (' DUSP6%0'  ' AP1_c%0')  (' DUSP6%0'  ' ACVR1%0')  (' DUSP6%0'  ' PTPN6%0')  (' DUSP6%0'  ' CDC42%0')  (' DUSP6%0'  ' GRB2%0')  (' DUSP6%0'  ' TGFBR1%0')  (' DUSP6%0'  ' SMURF1%0')  (' DUSP6%0'  ' SMURF2%0')  (' DUSP6%0'  ' RHOA%0')  (' DUSP6%0'  ' BMPR2%0')  (' DUSP6%0'  ' PARD6A%0')  (' DUSP6%0'  ' DAAM1%0')  (' DUSP6%0'  ' SFRP1_g%0')  (' DUSP6%0'  ' PPM1A%0')  (' DUSP6%0'  ' CFL_f%0')  (' DUSP6%0'  ' PAK1%0')  (' DUSP6%0'  ' MAP3K11%0')  (' DUSP6%0'  ' MAP3K4%0')  (' DUSP6%0'  ' LIMK1%0')  (' DUSP6%0'  ' ROCK1%0')  (' DUSP6%0'  ' ITCH%0')  (' DUSP6%0'  ' ARHGAP24%0')  (' DUSP6%0'  ' TIAM1%0')  (' DUSP6%0'  ' RND3%0')  (' DUSP6%0'  ' MAPK8IP3%0')  (' DUSP6%0'  ' MXD1%0')  (' DUSP6%0'  ' PIP3%0')  (' STAT3%0'  ' SRC%0')  (' STAT3%0'  ' CSK%0')  (' STAT3%0'  ' CHUK%0')  (' STAT3%0'  ' RAC_f%0')  (' STAT3%0'  ' DUSP1%0')  (' STAT3%0'  ' TGFBR2%0')  (' STAT3%0'  ' ILR_f%0')  (' STAT3%0'  ' SYK%0')  (' STAT3%0'  ' IRAK1%0')  (' STAT3%0'  ' SHC1%0')  (' STAT3%0'  ' JAK_f%0')  (' STAT3%0'  ' CBPp300_c%0')  (' STAT3%0'  ' SKP2%0')  (' STAT3%0'  ' TP53%0')  (' STAT3%0'  ' SMAD7%0')  (' STAT3%0'  ' SMAD6%0')  (' STAT3%0'  ' DKK_f%0')  (' STAT3%0'  ' FOXO_f%0')  (' STAT3%0'  ' TCF7_f%0')  (' STAT3%0'  ' DKK_g%0')  (' STAT3%0'  ' MYC%0')  (' STAT3%0'  ' CCND1%0')  (' STAT3%0'  ' EGR1%0')  (' STAT3%0'  ' MMP_f%0')  (' STAT3%0'  ' PTEN_g%0')  (' STAT3%0'  ' RTPK_f%0')  (' STAT3%0'  ' CTNNB1%0')  (' STAT3%0'  'LEF1%0')  (' STAT3%0'  'SFRP1%0')  (' STAT3%0'  'FZD_f%0')  (' STAT3%0'  ' CASP8%0')  (' STAT3%0'  ' REL_f%0')  (' STAT3%0'  ' NFKB_f%0')  (' STAT3%0'  ' DVL_f%0')  (' STAT3%0'  ' LRP_f%0')  (' STAT3%0'  ' BTRC%0')  (' STAT3%0'  ' CK1_f%0')  (' STAT3%0'  ' AXIN1%0')  (' STAT3%0'  ' mTORC2_c%0')  (' STAT3%0'  ' PDPK1%0')  (' STAT3%0'  ' MEK_f%0')  (' STAT3%0'  ' CYCS%0')  (' STAT3%0'  ' CASP9%0')  (' STAT3%0'  ' GSK3_f%0')  (' STAT3%0'  ' IRS1%0')  (' STAT3%0'  ' MDM2%0')  (' STAT3%0'  ' AKT_f%0')  (' STAT3%0'  ' BCL2%0')  (' STAT3%0'  ' RAF_f%0')  (' STAT3%0'  ' mTORC1_c%0')  (' STAT3%0'  ' RHEB%0')  (' STAT3%0'  ' RTPK_g%0')  (' STAT3%0'  ' PTEN%0')  (' STAT3%0'  ' CASP3%0')  (' STAT3%0'  ' PIK3CA%0')  (' STAT3%0'  ' CREBBP%0')  (' STAT3%0'  ' PTPN11%0')  (' STAT3%0'  ' KRAS%0')  (' STAT3%0'  ' MAP2K4%0')  (' STAT3%0'  ' MAP2K7%0')  (' STAT3%0'  ' MAPK14%0')  (' STAT3%0'  ' JNK_f%0')  (' STAT3%0'  ' MAP2K3%0')  (' STAT3%0'  ' ERK_f%0')  (' STAT3%0'  ' LIF%0')  (' STAT3%0'  ' PPP1CA%0')  (' STAT3%0'  ' GAB_f%0')  (' STAT3%0'  ' SOS1%0')  (' STAT3%0'  ' PRKCA%0')  (' STAT3%0'  ' VAV1%0')  (' STAT3%0'  ' PLCG1%0')  (' STAT3%0'  ' PRKCD%0')  (' STAT3%0'  ' RSK_f%0')  (' STAT3%0'  ' S6K_f%0')  (' STAT3%0'  ' PLK1%0')  (' STAT3%0'  ' ILK%0')  (' STAT3%0'  ' SOCS1%0')  (' STAT3%0'  ' DUSP6%0')  (' STAT3%0'  ' LIMK2%0')  (' STAT3%0'  ' EP300%0')  (' STAT3%0'  ' STAT1%0')  (' STAT3%0'  ' IKBKB%0')  (' STAT3%0'  ' SRF%0')  (' STAT3%0'  ' PIAS1%0')  (' STAT3%0'  ' TRAF6%0')  (' STAT3%0'  ' SOCS1_g%0')  (' STAT3%0'  ' ISGF3_c%0')  (' STAT3%0'  ' STAT2%0')  (' STAT3%0'  ' CFLAR%0')  (' STAT3%0'  ' SMAD2%0')  (' STAT3%0'  ' MDM2_g%0')  (' STAT3%0'  ' BAX%0')  (' STAT3%0'  ' PRKACA%0')  (' STAT3%0'  ' TGFB1%0')  (' STAT3%0'  ' MAP3K8%0')  (' STAT3%0'  ' TSC_f%0')  (' STAT3%0'  ' SMAD4%0')  (' STAT3%0'  ' BAD%0')  (' STAT3%0'  ' MAP3K5%0')  (' STAT3%0'  ' AKT1S1%0')  (' STAT3%0'  ' SKI%0')  (' STAT3%0'  ' SMAD3%0')  (' STAT3%0'  ' MAPKAPK2%0')  (' STAT3%0'  ' DUSP1_g%0')  (' STAT3%0'  ' MSK_f%0')  (' STAT3%0'  ' GRAP2%0')  (' STAT3%0'  ' TAB_f%0')  (' STAT3%0'  ' ATF2%0')  (' STAT3%0'  ' SMAD5%0')  (' STAT3%0'  ' SMAD1%0')  (' STAT3%0'  ' FOS%0')  (' STAT3%0'  ' JUN%0')  (' STAT3%0'  ' MAP3K7%0')  (' STAT3%0'  ' NLK%0')  (' STAT3%0'  ' SMAD7_g%0')  (' STAT3%0'  ' SMAD6_g%0')  (' STAT3%0'  ' AP1_c%0')  (' STAT3%0'  ' ACVR1%0')  (' STAT3%0'  ' PTPN6%0')  (' STAT3%0'  ' CDC42%0')  (' STAT3%0'  ' GRB2%0')  (' STAT3%0'  ' TGFBR1%0')  (' STAT3%0'  ' SMURF1%0')  (' STAT3%0'  ' SMURF2%0')  (' STAT3%0'  ' RHOA%0')  (' STAT3%0'  ' BMPR2%0')  (' STAT3%0'  ' PARD6A%0')  (' STAT3%0'  ' DAAM1%0')  (' STAT3%0'  ' SFRP1_g%0')  (' STAT3%0'  ' PPM1A%0')  (' STAT3%0'  ' CFL_f%0')  (' STAT3%0'  ' PAK1%0')  (' STAT3%0'  ' MAP3K11%0')  (' STAT3%0'  ' MAP3K4%0')  (' STAT3%0'  ' LIMK1%0')  (' STAT3%0'  ' ROCK1%0')  (' STAT3%0'  ' ITCH%0')  (' STAT3%0'  ' ARHGAP24%0')  (' STAT3%0'  ' TIAM1%0')  (' STAT3%0'  ' RND3%0')  (' STAT3%0'  ' MAPK8IP3%0')  (' STAT3%0'  ' MXD1%0')  (' STAT3%0'  ' PIP3%0')  (' LIMK2%0'  ' SRC%0')  (' LIMK2%0'  ' CSK%0')  (' LIMK2%0'  ' CHUK%0')  (' LIMK2%0'  ' RAC_f%0')  (' LIMK2%0'  ' DUSP1%0')  (' LIMK2%0'  ' TGFBR2%0')  (' LIMK2%0'  ' ILR_f%0')  (' LIMK2%0'  ' SYK%0')  (' LIMK2%0'  ' IRAK1%0')  (' LIMK2%0'  ' SHC1%0')  (' LIMK2%0'  ' JAK_f%0')  (' LIMK2%0'  ' CBPp300_c%0')  (' LIMK2%0'  ' SKP2%0')  (' LIMK2%0'  ' TP53%0')  (' LIMK2%0'  ' SMAD7%0')  (' LIMK2%0'  ' SMAD6%0')  (' LIMK2%0'  ' DKK_f%0')  (' LIMK2%0'  ' FOXO_f%0')  (' LIMK2%0'  ' TCF7_f%0')  (' LIMK2%0'  ' DKK_g%0')  (' LIMK2%0'  ' MYC%0')  (' LIMK2%0'  ' CCND1%0')  (' LIMK2%0'  ' EGR1%0')  (' LIMK2%0'  ' MMP_f%0')  (' LIMK2%0'  ' PTEN_g%0')  (' LIMK2%0'  ' RTPK_f%0')  (' LIMK2%0'  ' CTNNB1%0')  (' LIMK2%0'  'LEF1%0')  (' LIMK2%0'  'SFRP1%0')  (' LIMK2%0'  'FZD_f%0')  (' LIMK2%0'  ' CASP8%0')  (' LIMK2%0'  ' REL_f%0')  (' LIMK2%0'  ' NFKB_f%0')  (' LIMK2%0'  ' DVL_f%0')  (' LIMK2%0'  ' LRP_f%0')  (' LIMK2%0'  ' BTRC%0')  (' LIMK2%0'  ' CK1_f%0')  (' LIMK2%0'  ' AXIN1%0')  (' LIMK2%0'  ' mTORC2_c%0')  (' LIMK2%0'  ' PDPK1%0')  (' LIMK2%0'  ' MEK_f%0')  (' LIMK2%0'  ' CYCS%0')  (' LIMK2%0'  ' CASP9%0')  (' LIMK2%0'  ' GSK3_f%0')  (' LIMK2%0'  ' IRS1%0')  (' LIMK2%0'  ' MDM2%0')  (' LIMK2%0'  ' AKT_f%0')  (' LIMK2%0'  ' BCL2%0')  (' LIMK2%0'  ' RAF_f%0')  (' LIMK2%0'  ' mTORC1_c%0')  (' LIMK2%0'  ' RHEB%0')  (' LIMK2%0'  ' RTPK_g%0')  (' LIMK2%0'  ' PTEN%0')  (' LIMK2%0'  ' CASP3%0')  (' LIMK2%0'  ' PIK3CA%0')  (' LIMK2%0'  ' CREBBP%0')  (' LIMK2%0'  ' PTPN11%0')  (' LIMK2%0'  ' KRAS%0')  (' LIMK2%0'  ' MAP2K4%0')  (' LIMK2%0'  ' MAP2K7%0')  (' LIMK2%0'  ' MAPK14%0')  (' LIMK2%0'  ' JNK_f%0')  (' LIMK2%0'  ' MAP2K3%0')  (' LIMK2%0'  ' ERK_f%0')  (' LIMK2%0'  ' LIF%0')  (' LIMK2%0'  ' PPP1CA%0')  (' LIMK2%0'  ' GAB_f%0')  (' LIMK2%0'  ' SOS1%0')  (' LIMK2%0'  ' PRKCA%0')  (' LIMK2%0'  ' VAV1%0')  (' LIMK2%0'  ' PLCG1%0')  (' LIMK2%0'  ' PRKCD%0')  (' LIMK2%0'  ' RSK_f%0')  (' LIMK2%0'  ' S6K_f%0')  (' LIMK2%0'  ' PLK1%0')  (' LIMK2%0'  ' ILK%0')  (' LIMK2%0'  ' SOCS1%0')  (' LIMK2%0'  ' DUSP6%0')  (' LIMK2%0'  ' STAT3%0')  (' LIMK2%0'  ' EP300%0')  (' LIMK2%0'  ' STAT1%0')  (' LIMK2%0'  ' IKBKB%0')  (' LIMK2%0'  ' SRF%0')  (' LIMK2%0'  ' PIAS1%0')  (' LIMK2%0'  ' TRAF6%0')  (' LIMK2%0'  ' SOCS1_g%0')  (' LIMK2%0'  ' ISGF3_c%0')  (' LIMK2%0'  ' STAT2%0')  (' LIMK2%0'  ' CFLAR%0')  (' LIMK2%0'  ' SMAD2%0')  (' LIMK2%0'  ' MDM2_g%0')  (' LIMK2%0'  ' BAX%0')  (' LIMK2%0'  ' PRKACA%0')  (' LIMK2%0'  ' TGFB1%0')  (' LIMK2%0'  ' MAP3K8%0')  (' LIMK2%0'  ' TSC_f%0')  (' LIMK2%0'  ' SMAD4%0')  (' LIMK2%0'  ' BAD%0')  (' LIMK2%0'  ' MAP3K5%0')  (' LIMK2%0'  ' AKT1S1%0')  (' LIMK2%0'  ' SKI%0')  (' LIMK2%0'  ' SMAD3%0')  (' LIMK2%0'  ' MAPKAPK2%0')  (' LIMK2%0'  ' DUSP1_g%0')  (' LIMK2%0'  ' MSK_f%0')  (' LIMK2%0'  ' GRAP2%0')  (' LIMK2%0'  ' TAB_f%0')  (' LIMK2%0'  ' ATF2%0')  (' LIMK2%0'  ' SMAD5%0')  (' LIMK2%0'  ' SMAD1%0')  (' LIMK2%0'  ' FOS%0')  (' LIMK2%0'  ' JUN%0')  (' LIMK2%0'  ' MAP3K7%0')  (' LIMK2%0'  ' NLK%0')  (' LIMK2%0'  ' SMAD7_g%0')  (' LIMK2%0'  ' SMAD6_g%0')  (' LIMK2%0'  ' AP1_c%0')  (' LIMK2%0'  ' ACVR1%0')  (' LIMK2%0'  ' PTPN6%0')  (' LIMK2%0'  ' CDC42%0')  (' LIMK2%0'  ' GRB2%0')  (' LIMK2%0'  ' TGFBR1%0')  (' LIMK2%0'  ' SMURF1%0')  (' LIMK2%0'  ' SMURF2%0')  (' LIMK2%0'  ' RHOA%0')  (' LIMK2%0'  ' BMPR2%0')  (' LIMK2%0'  ' PARD6A%0')  (' LIMK2%0'  ' DAAM1%0')  (' LIMK2%0'  ' SFRP1_g%0')  (' LIMK2%0'  ' PPM1A%0')  (' LIMK2%0'  ' CFL_f%0')  (' LIMK2%0'  ' PAK1%0')  (' LIMK2%0'  ' MAP3K11%0')  (' LIMK2%0'  ' MAP3K4%0')  (' LIMK2%0'  ' LIMK1%0')  (' LIMK2%0'  ' ROCK1%0')  (' LIMK2%0'  ' ITCH%0')  (' LIMK2%0'  ' ARHGAP24%0')  (' LIMK2%0'  ' TIAM1%0')  (' LIMK2%0'  ' RND3%0')  (' LIMK2%0'  ' MAPK8IP3%0')  (' LIMK2%0'  ' MXD1%0')  (' LIMK2%0'  ' PIP3%0')  (' EP300%0'  ' SRC%0')  (' EP300%0'  ' CSK%0')  (' EP300%0'  ' CHUK%0')  (' EP300%0'  ' RAC_f%0')  (' EP300%0'  ' DUSP1%0')  (' EP300%0'  ' TGFBR2%0')  (' EP300%0'  ' ILR_f%0')  (' EP300%0'  ' SYK%0')  (' EP300%0'  ' IRAK1%0')  (' EP300%0'  ' SHC1%0')  (' EP300%0'  ' JAK_f%0')  (' EP300%0'  ' CBPp300_c%0')  (' EP300%0'  ' SKP2%0')  (' EP300%0'  ' TP53%0')  (' EP300%0'  ' SMAD7%0')  (' EP300%0'  ' SMAD6%0')  (' EP300%0'  ' DKK_f%0')  (' EP300%0'  ' FOXO_f%0')  (' EP300%0'  ' TCF7_f%0')  (' EP300%0'  ' DKK_g%0')  (' EP300%0'  ' MYC%0')  (' EP300%0'  ' CCND1%0')  (' EP300%0'  ' EGR1%0')  (' EP300%0'  ' MMP_f%0')  (' EP300%0'  ' PTEN_g%0')  (' EP300%0'  ' RTPK_f%0')  (' EP300%0'  ' CTNNB1%0')  (' EP300%0'  'LEF1%0')  (' EP300%0'  'SFRP1%0')  (' EP300%0'  'FZD_f%0')  (' EP300%0'  ' CASP8%0')  (' EP300%0'  ' REL_f%0')  (' EP300%0'  ' NFKB_f%0')  (' EP300%0'  ' DVL_f%0')  (' EP300%0'  ' LRP_f%0')  (' EP300%0'  ' BTRC%0')  (' EP300%0'  ' CK1_f%0')  (' EP300%0'  ' AXIN1%0')  (' EP300%0'  ' mTORC2_c%0')  (' EP300%0'  ' PDPK1%0')  (' EP300%0'  ' MEK_f%0')  (' EP300%0'  ' CYCS%0')  (' EP300%0'  ' CASP9%0')  (' EP300%0'  ' GSK3_f%0')  (' EP300%0'  ' IRS1%0')  (' EP300%0'  ' MDM2%0')  (' EP300%0'  ' AKT_f%0')  (' EP300%0'  ' BCL2%0')  (' EP300%0'  ' RAF_f%0')  (' EP300%0'  ' mTORC1_c%0')  (' EP300%0'  ' RHEB%0')  (' EP300%0'  ' RTPK_g%0')  (' EP300%0'  ' PTEN%0')  (' EP300%0'  ' CASP3%0')  (' EP300%0'  ' PIK3CA%0')  (' EP300%0'  ' CREBBP%0')  (' EP300%0'  ' PTPN11%0')  (' EP300%0'  ' KRAS%0')  (' EP300%0'  ' MAP2K4%0')  (' EP300%0'  ' MAP2K7%0')  (' EP300%0'  ' MAPK14%0')  (' EP300%0'  ' JNK_f%0')  (' EP300%0'  ' MAP2K3%0')  (' EP300%0'  ' ERK_f%0')  (' EP300%0'  ' LIF%0')  (' EP300%0'  ' PPP1CA%0')  (' EP300%0'  ' GAB_f%0')  (' EP300%0'  ' SOS1%0')  (' EP300%0'  ' PRKCA%0')  (' EP300%0'  ' VAV1%0')  (' EP300%0'  ' PLCG1%0')  (' EP300%0'  ' PRKCD%0')  (' EP300%0'  ' RSK_f%0')  (' EP300%0'  ' S6K_f%0')  (' EP300%0'  ' PLK1%0')  (' EP300%0'  ' ILK%0')  (' EP300%0'  ' SOCS1%0')  (' EP300%0'  ' DUSP6%0')  (' EP300%0'  ' STAT3%0')  (' EP300%0'  ' LIMK2%0')  (' EP300%0'  ' STAT1%0')  (' EP300%0'  ' IKBKB%0')  (' EP300%0'  ' SRF%0')  (' EP300%0'  ' PIAS1%0')  (' EP300%0'  ' TRAF6%0')  (' EP300%0'  ' SOCS1_g%0')  (' EP300%0'  ' ISGF3_c%0')  (' EP300%0'  ' STAT2%0')  (' EP300%0'  ' CFLAR%0')  (' EP300%0'  ' SMAD2%0')  (' EP300%0'  ' MDM2_g%0')  (' EP300%0'  ' BAX%0')  (' EP300%0'  ' PRKACA%0')  (' EP300%0'  ' TGFB1%0')  (' EP300%0'  ' MAP3K8%0')  (' EP300%0'  ' TSC_f%0')  (' EP300%0'  ' SMAD4%0')  (' EP300%0'  ' BAD%0')  (' EP300%0'  ' MAP3K5%0')  (' EP300%0'  ' AKT1S1%0')  (' EP300%0'  ' SKI%0')  (' EP300%0'  ' SMAD3%0')  (' EP300%0'  ' MAPKAPK2%0')  (' EP300%0'  ' DUSP1_g%0')  (' EP300%0'  ' MSK_f%0')  (' EP300%0'  ' GRAP2%0')  (' EP300%0'  ' TAB_f%0')  (' EP300%0'  ' ATF2%0')  (' EP300%0'  ' SMAD5%0')  (' EP300%0'  ' SMAD1%0')  (' EP300%0'  ' FOS%0')  (' EP300%0'  ' JUN%0')  (' EP300%0'  ' MAP3K7%0')  (' EP300%0'  ' NLK%0')  (' EP300%0'  ' SMAD7_g%0')  (' EP300%0'  ' SMAD6_g%0')  (' EP300%0'  ' AP1_c%0')  (' EP300%0'  ' ACVR1%0')  (' EP300%0'  ' PTPN6%0')  (' EP300%0'  ' CDC42%0')  (' EP300%0'  ' GRB2%0')  (' EP300%0'  ' TGFBR1%0')  (' EP300%0'  ' SMURF1%0')  (' EP300%0'  ' SMURF2%0')  (' EP300%0'  ' RHOA%0')  (' EP300%0'  ' BMPR2%0')  (' EP300%0'  ' PARD6A%0')  (' EP300%0'  ' DAAM1%0')  (' EP300%0'  ' SFRP1_g%0')  (' EP300%0'  ' PPM1A%0')  (' EP300%0'  ' CFL_f%0')  (' EP300%0'  ' PAK1%0')  (' EP300%0'  ' MAP3K11%0')  (' EP300%0'  ' MAP3K4%0')  (' EP300%0'  ' LIMK1%0')  (' EP300%0'  ' ROCK1%0')  (' EP300%0'  ' ITCH%0')  (' EP300%0'  ' ARHGAP24%0')  (' EP300%0'  ' TIAM1%0')  (' EP300%0'  ' RND3%0')  (' EP300%0'  ' MAPK8IP3%0')  (' EP300%0'  ' MXD1%0')  (' EP300%0'  ' PIP3%0')  (' STAT1%0'  ' SRC%0')  (' STAT1%0'  ' CSK%0')  (' STAT1%0'  ' CHUK%0')  (' STAT1%0'  ' RAC_f%0')  (' STAT1%0'  ' DUSP1%0')  (' STAT1%0'  ' TGFBR2%0')  (' STAT1%0'  ' ILR_f%0')  (' STAT1%0'  ' SYK%0')  (' STAT1%0'  ' IRAK1%0')  (' STAT1%0'  ' SHC1%0')  (' STAT1%0'  ' JAK_f%0')  (' STAT1%0'  ' CBPp300_c%0')  (' STAT1%0'  ' SKP2%0')  (' STAT1%0'  ' TP53%0')  (' STAT1%0'  ' SMAD7%0')  (' STAT1%0'  ' SMAD6%0')  (' STAT1%0'  ' DKK_f%0')  (' STAT1%0'  ' FOXO_f%0')  (' STAT1%0'  ' TCF7_f%0')  (' STAT1%0'  ' DKK_g%0')  (' STAT1%0'  ' MYC%0')  (' STAT1%0'  ' CCND1%0')  (' STAT1%0'  ' EGR1%0')  (' STAT1%0'  ' MMP_f%0')  (' STAT1%0'  ' PTEN_g%0')  (' STAT1%0'  ' RTPK_f%0')  (' STAT1%0'  ' CTNNB1%0')  (' STAT1%0'  'LEF1%0')  (' STAT1%0'  'SFRP1%0')  (' STAT1%0'  'FZD_f%0')  (' STAT1%0'  ' CASP8%0')  (' STAT1%0'  ' REL_f%0')  (' STAT1%0'  ' NFKB_f%0')  (' STAT1%0'  ' DVL_f%0')  (' STAT1%0'  ' LRP_f%0')  (' STAT1%0'  ' BTRC%0')  (' STAT1%0'  ' CK1_f%0')  (' STAT1%0'  ' AXIN1%0')  (' STAT1%0'  ' mTORC2_c%0')  (' STAT1%0'  ' PDPK1%0')  (' STAT1%0'  ' MEK_f%0')  (' STAT1%0'  ' CYCS%0')  (' STAT1%0'  ' CASP9%0')  (' STAT1%0'  ' GSK3_f%0')  (' STAT1%0'  ' IRS1%0')  (' STAT1%0'  ' MDM2%0')  (' STAT1%0'  ' AKT_f%0')  (' STAT1%0'  ' BCL2%0')  (' STAT1%0'  ' RAF_f%0')  (' STAT1%0'  ' mTORC1_c%0')  (' STAT1%0'  ' RHEB%0')  (' STAT1%0'  ' RTPK_g%0')  (' STAT1%0'  ' PTEN%0')  (' STAT1%0'  ' CASP3%0')  (' STAT1%0'  ' PIK3CA%0')  (' STAT1%0'  ' CREBBP%0')  (' STAT1%0'  ' PTPN11%0')  (' STAT1%0'  ' KRAS%0')  (' STAT1%0'  ' MAP2K4%0')  (' STAT1%0'  ' MAP2K7%0')  (' STAT1%0'  ' MAPK14%0')  (' STAT1%0'  ' JNK_f%0')  (' STAT1%0'  ' MAP2K3%0')  (' STAT1%0'  ' ERK_f%0')  (' STAT1%0'  ' LIF%0')  (' STAT1%0'  ' PPP1CA%0')  (' STAT1%0'  ' GAB_f%0')  (' STAT1%0'  ' SOS1%0')  (' STAT1%0'  ' PRKCA%0')  (' STAT1%0'  ' VAV1%0')  (' STAT1%0'  ' PLCG1%0')  (' STAT1%0'  ' PRKCD%0')  (' STAT1%0'  ' RSK_f%0')  (' STAT1%0'  ' S6K_f%0')  (' STAT1%0'  ' PLK1%0')  (' STAT1%0'  ' ILK%0')  (' STAT1%0'  ' SOCS1%0')  (' STAT1%0'  ' DUSP6%0')  (' STAT1%0'  ' STAT3%0')  (' STAT1%0'  ' LIMK2%0')  (' STAT1%0'  ' EP300%0')  (' STAT1%0'  ' IKBKB%0')  (' STAT1%0'  ' SRF%0')  (' STAT1%0'  ' PIAS1%0')  (' STAT1%0'  ' TRAF6%0')  (' STAT1%0'  ' SOCS1_g%0')  (' STAT1%0'  ' ISGF3_c%0')  (' STAT1%0'  ' STAT2%0')  (' STAT1%0'  ' CFLAR%0')  (' STAT1%0'  ' SMAD2%0')  (' STAT1%0'  ' MDM2_g%0')  (' STAT1%0'  ' BAX%0')  (' STAT1%0'  ' PRKACA%0')  (' STAT1%0'  ' TGFB1%0')  (' STAT1%0'  ' MAP3K8%0')  (' STAT1%0'  ' TSC_f%0')  (' STAT1%0'  ' SMAD4%0')  (' STAT1%0'  ' BAD%0')  (' STAT1%0'  ' MAP3K5%0')  (' STAT1%0'  ' AKT1S1%0')  (' STAT1%0'  ' SKI%0')  (' STAT1%0'  ' SMAD3%0')  (' STAT1%0'  ' MAPKAPK2%0')  (' STAT1%0'  ' DUSP1_g%0')  (' STAT1%0'  ' MSK_f%0')  (' STAT1%0'  ' GRAP2%0')  (' STAT1%0'  ' TAB_f%0')  (' STAT1%0'  ' ATF2%0')  (' STAT1%0'  ' SMAD5%0')  (' STAT1%0'  ' SMAD1%0')  (' STAT1%0'  ' FOS%0')  (' STAT1%0'  ' JUN%0')  (' STAT1%0'  ' MAP3K7%0')  (' STAT1%0'  ' NLK%0')  (' STAT1%0'  ' SMAD7_g%0')  (' STAT1%0'  ' SMAD6_g%0')  (' STAT1%0'  ' AP1_c%0')  (' STAT1%0'  ' ACVR1%0')  (' STAT1%0'  ' PTPN6%0')  (' STAT1%0'  ' CDC42%0')  (' STAT1%0'  ' GRB2%0')  (' STAT1%0'  ' TGFBR1%0')  (' STAT1%0'  ' SMURF1%0')  (' STAT1%0'  ' SMURF2%0')  (' STAT1%0'  ' RHOA%0')  (' STAT1%0'  ' BMPR2%0')  (' STAT1%0'  ' PARD6A%0')  (' STAT1%0'  ' DAAM1%0')  (' STAT1%0'  ' SFRP1_g%0')  (' STAT1%0'  ' PPM1A%0')  (' STAT1%0'  ' CFL_f%0')  (' STAT1%0'  ' PAK1%0')  (' STAT1%0'  ' MAP3K11%0')  (' STAT1%0'  ' MAP3K4%0')  (' STAT1%0'  ' LIMK1%0')  (' STAT1%0'  ' ROCK1%0')  (' STAT1%0'  ' ITCH%0')  (' STAT1%0'  ' ARHGAP24%0')  (' STAT1%0'  ' TIAM1%0')  (' STAT1%0'  ' RND3%0')  (' STAT1%0'  ' MAPK8IP3%0')  (' STAT1%0'  ' MXD1%0')  (' STAT1%0'  ' PIP3%0')  (' IKBKB%0'  ' SRC%0')  (' IKBKB%0'  ' CSK%0')  (' IKBKB%0'  ' CHUK%0')  (' IKBKB%0'  ' RAC_f%0')  (' IKBKB%0'  ' DUSP1%0')  (' IKBKB%0'  ' TGFBR2%0')  (' IKBKB%0'  ' ILR_f%0')  (' IKBKB%0'  ' SYK%0')  (' IKBKB%0'  ' IRAK1%0')  (' IKBKB%0'  ' SHC1%0')  (' IKBKB%0'  ' JAK_f%0')  (' IKBKB%0'  ' CBPp300_c%0')  (' IKBKB%0'  ' SKP2%0')  (' IKBKB%0'  ' TP53%0')  (' IKBKB%0'  ' SMAD7%0')  (' IKBKB%0'  ' SMAD6%0')  (' IKBKB%0'  ' DKK_f%0')  (' IKBKB%0'  ' FOXO_f%0')  (' IKBKB%0'  ' TCF7_f%0')  (' IKBKB%0'  ' DKK_g%0')  (' IKBKB%0'  ' MYC%0')  (' IKBKB%0'  ' CCND1%0')  (' IKBKB%0'  ' EGR1%0')  (' IKBKB%0'  ' MMP_f%0')  (' IKBKB%0'  ' PTEN_g%0')  (' IKBKB%0'  ' RTPK_f%0')  (' IKBKB%0'  ' CTNNB1%0')  (' IKBKB%0'  'LEF1%0')  (' IKBKB%0'  'SFRP1%0')  (' IKBKB%0'  'FZD_f%0')  (' IKBKB%0'  ' CASP8%0')  (' IKBKB%0'  ' REL_f%0')  (' IKBKB%0'  ' NFKB_f%0')  (' IKBKB%0'  ' DVL_f%0')  (' IKBKB%0'  ' LRP_f%0')  (' IKBKB%0'  ' BTRC%0')  (' IKBKB%0'  ' CK1_f%0')  (' IKBKB%0'  ' AXIN1%0')  (' IKBKB%0'  ' mTORC2_c%0')  (' IKBKB%0'  ' PDPK1%0')  (' IKBKB%0'  ' MEK_f%0')  (' IKBKB%0'  ' CYCS%0')  (' IKBKB%0'  ' CASP9%0')  (' IKBKB%0'  ' GSK3_f%0')  (' IKBKB%0'  ' IRS1%0')  (' IKBKB%0'  ' MDM2%0')  (' IKBKB%0'  ' AKT_f%0')  (' IKBKB%0'  ' BCL2%0')  (' IKBKB%0'  ' RAF_f%0')  (' IKBKB%0'  ' mTORC1_c%0')  (' IKBKB%0'  ' RHEB%0')  (' IKBKB%0'  ' RTPK_g%0')  (' IKBKB%0'  ' PTEN%0')  (' IKBKB%0'  ' CASP3%0')  (' IKBKB%0'  ' PIK3CA%0')  (' IKBKB%0'  ' CREBBP%0')  (' IKBKB%0'  ' PTPN11%0')  (' IKBKB%0'  ' KRAS%0')  (' IKBKB%0'  ' MAP2K4%0')  (' IKBKB%0'  ' MAP2K7%0')  (' IKBKB%0'  ' MAPK14%0')  (' IKBKB%0'  ' JNK_f%0')  (' IKBKB%0'  ' MAP2K3%0')  (' IKBKB%0'  ' ERK_f%0')  (' IKBKB%0'  ' LIF%0')  (' IKBKB%0'  ' PPP1CA%0')  (' IKBKB%0'  ' GAB_f%0')  (' IKBKB%0'  ' SOS1%0')  (' IKBKB%0'  ' PRKCA%0')  (' IKBKB%0'  ' VAV1%0')  (' IKBKB%0'  ' PLCG1%0')  (' IKBKB%0'  ' PRKCD%0')  (' IKBKB%0'  ' RSK_f%0')  (' IKBKB%0'  ' S6K_f%0')  (' IKBKB%0'  ' PLK1%0')  (' IKBKB%0'  ' ILK%0')  (' IKBKB%0'  ' SOCS1%0')  (' IKBKB%0'  ' DUSP6%0')  (' IKBKB%0'  ' STAT3%0')  (' IKBKB%0'  ' LIMK2%0')  (' IKBKB%0'  ' EP300%0')  (' IKBKB%0'  ' STAT1%0')  (' IKBKB%0'  ' SRF%0')  (' IKBKB%0'  ' PIAS1%0')  (' IKBKB%0'  ' TRAF6%0')  (' IKBKB%0'  ' SOCS1_g%0')  (' IKBKB%0'  ' ISGF3_c%0')  (' IKBKB%0'  ' STAT2%0')  (' IKBKB%0'  ' CFLAR%0')  (' IKBKB%0'  ' SMAD2%0')  (' IKBKB%0'  ' MDM2_g%0')  (' IKBKB%0'  ' BAX%0')  (' IKBKB%0'  ' PRKACA%0')  (' IKBKB%0'  ' TGFB1%0')  (' IKBKB%0'  ' MAP3K8%0')  (' IKBKB%0'  ' TSC_f%0')  (' IKBKB%0'  ' SMAD4%0')  (' IKBKB%0'  ' BAD%0')  (' IKBKB%0'  ' MAP3K5%0')  (' IKBKB%0'  ' AKT1S1%0')  (' IKBKB%0'  ' SKI%0')  (' IKBKB%0'  ' SMAD3%0')  (' IKBKB%0'  ' MAPKAPK2%0')  (' IKBKB%0'  ' DUSP1_g%0')  (' IKBKB%0'  ' MSK_f%0')  (' IKBKB%0'  ' GRAP2%0')  (' IKBKB%0'  ' TAB_f%0')  (' IKBKB%0'  ' ATF2%0')  (' IKBKB%0'  ' SMAD5%0')  (' IKBKB%0'  ' SMAD1%0')  (' IKBKB%0'  ' FOS%0')  (' IKBKB%0'  ' JUN%0')  (' IKBKB%0'  ' MAP3K7%0')  (' IKBKB%0'  ' NLK%0')  (' IKBKB%0'  ' SMAD7_g%0')  (' IKBKB%0'  ' SMAD6_g%0')  (' IKBKB%0'  ' AP1_c%0')  (' IKBKB%0'  ' ACVR1%0')  (' IKBKB%0'  ' PTPN6%0')  (' IKBKB%0'  ' CDC42%0')  (' IKBKB%0'  ' GRB2%0')  (' IKBKB%0'  ' TGFBR1%0')  (' IKBKB%0'  ' SMURF1%0')  (' IKBKB%0'  ' SMURF2%0')  (' IKBKB%0'  ' RHOA%0')  (' IKBKB%0'  ' BMPR2%0')  (' IKBKB%0'  ' PARD6A%0')  (' IKBKB%0'  ' DAAM1%0')  (' IKBKB%0'  ' SFRP1_g%0')  (' IKBKB%0'  ' PPM1A%0')  (' IKBKB%0'  ' CFL_f%0')  (' IKBKB%0'  ' PAK1%0')  (' IKBKB%0'  ' MAP3K11%0')  (' IKBKB%0'  ' MAP3K4%0')  (' IKBKB%0'  ' LIMK1%0')  (' IKBKB%0'  ' ROCK1%0')  (' IKBKB%0'  ' ITCH%0')  (' IKBKB%0'  ' ARHGAP24%0')  (' IKBKB%0'  ' TIAM1%0')  (' IKBKB%0'  ' RND3%0')  (' IKBKB%0'  ' MAPK8IP3%0')  (' IKBKB%0'  ' MXD1%0')  (' IKBKB%0'  ' PIP3%0')  (' SRF%0'  ' SRC%0')  (' SRF%0'  ' CSK%0')  (' SRF%0'  ' CHUK%0')  (' SRF%0'  ' RAC_f%0')  (' SRF%0'  ' DUSP1%0')  (' SRF%0'  ' TGFBR2%0')  (' SRF%0'  ' ILR_f%0')  (' SRF%0'  ' SYK%0')  (' SRF%0'  ' IRAK1%0')  (' SRF%0'  ' SHC1%0')  (' SRF%0'  ' JAK_f%0')  (' SRF%0'  ' CBPp300_c%0')  (' SRF%0'  ' SKP2%0')  (' SRF%0'  ' TP53%0')  (' SRF%0'  ' SMAD7%0')  (' SRF%0'  ' SMAD6%0')  (' SRF%0'  ' DKK_f%0')  (' SRF%0'  ' FOXO_f%0')  (' SRF%0'  ' TCF7_f%0')  (' SRF%0'  ' DKK_g%0')  (' SRF%0'  ' MYC%0')  (' SRF%0'  ' CCND1%0')  (' SRF%0'  ' EGR1%0')  (' SRF%0'  ' MMP_f%0')  (' SRF%0'  ' PTEN_g%0')  (' SRF%0'  ' RTPK_f%0')  (' SRF%0'  ' CTNNB1%0')  (' SRF%0'  'LEF1%0')  (' SRF%0'  'SFRP1%0')  (' SRF%0'  'FZD_f%0')  (' SRF%0'  ' CASP8%0')  (' SRF%0'  ' REL_f%0')  (' SRF%0'  ' NFKB_f%0')  (' SRF%0'  ' DVL_f%0')  (' SRF%0'  ' LRP_f%0')  (' SRF%0'  ' BTRC%0')  (' SRF%0'  ' CK1_f%0')  (' SRF%0'  ' AXIN1%0')  (' SRF%0'  ' mTORC2_c%0')  (' SRF%0'  ' PDPK1%0')  (' SRF%0'  ' MEK_f%0')  (' SRF%0'  ' CYCS%0')  (' SRF%0'  ' CASP9%0')  (' SRF%0'  ' GSK3_f%0')  (' SRF%0'  ' IRS1%0')  (' SRF%0'  ' MDM2%0')  (' SRF%0'  ' AKT_f%0')  (' SRF%0'  ' BCL2%0')  (' SRF%0'  ' RAF_f%0')  (' SRF%0'  ' mTORC1_c%0')  (' SRF%0'  ' RHEB%0')  (' SRF%0'  ' RTPK_g%0')  (' SRF%0'  ' PTEN%0')  (' SRF%0'  ' CASP3%0')  (' SRF%0'  ' PIK3CA%0')  (' SRF%0'  ' CREBBP%0')  (' SRF%0'  ' PTPN11%0')  (' SRF%0'  ' KRAS%0')  (' SRF%0'  ' MAP2K4%0')  (' SRF%0'  ' MAP2K7%0')  (' SRF%0'  ' MAPK14%0')  (' SRF%0'  ' JNK_f%0')  (' SRF%0'  ' MAP2K3%0')  (' SRF%0'  ' ERK_f%0')  (' SRF%0'  ' LIF%0')  (' SRF%0'  ' PPP1CA%0')  (' SRF%0'  ' GAB_f%0')  (' SRF%0'  ' SOS1%0')  (' SRF%0'  ' PRKCA%0')  (' SRF%0'  ' VAV1%0')  (' SRF%0'  ' PLCG1%0')  (' SRF%0'  ' PRKCD%0')  (' SRF%0'  ' RSK_f%0')  (' SRF%0'  ' S6K_f%0')  (' SRF%0'  ' PLK1%0')  (' SRF%0'  ' ILK%0')  (' SRF%0'  ' SOCS1%0')  (' SRF%0'  ' DUSP6%0')  (' SRF%0'  ' STAT3%0')  (' SRF%0'  ' LIMK2%0')  (' SRF%0'  ' EP300%0')  (' SRF%0'  ' STAT1%0')  (' SRF%0'  ' IKBKB%0')  (' SRF%0'  ' PIAS1%0')  (' SRF%0'  ' TRAF6%0')  (' SRF%0'  ' SOCS1_g%0')  (' SRF%0'  ' ISGF3_c%0')  (' SRF%0'  ' STAT2%0')  (' SRF%0'  ' CFLAR%0')  (' SRF%0'  ' SMAD2%0')  (' SRF%0'  ' MDM2_g%0')  (' SRF%0'  ' BAX%0')  (' SRF%0'  ' PRKACA%0')  (' SRF%0'  ' TGFB1%0')  (' SRF%0'  ' MAP3K8%0')  (' SRF%0'  ' TSC_f%0')  (' SRF%0'  ' SMAD4%0')  (' SRF%0'  ' BAD%0')  (' SRF%0'  ' MAP3K5%0')  (' SRF%0'  ' AKT1S1%0')  (' SRF%0'  ' SKI%0')  (' SRF%0'  ' SMAD3%0')  (' SRF%0'  ' MAPKAPK2%0')  (' SRF%0'  ' DUSP1_g%0')  (' SRF%0'  ' MSK_f%0')  (' SRF%0'  ' GRAP2%0')  (' SRF%0'  ' TAB_f%0')  (' SRF%0'  ' ATF2%0')  (' SRF%0'  ' SMAD5%0')  (' SRF%0'  ' SMAD1%0')  (' SRF%0'  ' FOS%0')  (' SRF%0'  ' JUN%0')  (' SRF%0'  ' MAP3K7%0')  (' SRF%0'  ' NLK%0')  (' SRF%0'  ' SMAD7_g%0')  (' SRF%0'  ' SMAD6_g%0')  (' SRF%0'  ' AP1_c%0')  (' SRF%0'  ' ACVR1%0')  (' SRF%0'  ' PTPN6%0')  (' SRF%0'  ' CDC42%0')  (' SRF%0'  ' GRB2%0')  (' SRF%0'  ' TGFBR1%0')  (' SRF%0'  ' SMURF1%0')  (' SRF%0'  ' SMURF2%0')  (' SRF%0'  ' RHOA%0')  (' SRF%0'  ' BMPR2%0')  (' SRF%0'  ' PARD6A%0')  (' SRF%0'  ' DAAM1%0')  (' SRF%0'  ' SFRP1_g%0')  (' SRF%0'  ' PPM1A%0')  (' SRF%0'  ' CFL_f%0')  (' SRF%0'  ' PAK1%0')  (' SRF%0'  ' MAP3K11%0')  (' SRF%0'  ' MAP3K4%0')  (' SRF%0'  ' LIMK1%0')  (' SRF%0'  ' ROCK1%0')  (' SRF%0'  ' ITCH%0')  (' SRF%0'  ' ARHGAP24%0')  (' SRF%0'  ' TIAM1%0')  (' SRF%0'  ' RND3%0')  (' SRF%0'  ' MAPK8IP3%0')  (' SRF%0'  ' MXD1%0')  (' SRF%0'  ' PIP3%0')  (' PIAS1%0'  ' SRC%0')  (' PIAS1%0'  ' CSK%0')  (' PIAS1%0'  ' CHUK%0')  (' PIAS1%0'  ' RAC_f%0')  (' PIAS1%0'  ' DUSP1%0')  (' PIAS1%0'  ' TGFBR2%0')  (' PIAS1%0'  ' ILR_f%0')  (' PIAS1%0'  ' SYK%0')  (' PIAS1%0'  ' IRAK1%0')  (' PIAS1%0'  ' SHC1%0')  (' PIAS1%0'  ' JAK_f%0')  (' PIAS1%0'  ' CBPp300_c%0')  (' PIAS1%0'  ' SKP2%0')  (' PIAS1%0'  ' TP53%0')  (' PIAS1%0'  ' SMAD7%0')  (' PIAS1%0'  ' SMAD6%0')  (' PIAS1%0'  ' DKK_f%0')  (' PIAS1%0'  ' FOXO_f%0')  (' PIAS1%0'  ' TCF7_f%0')  (' PIAS1%0'  ' DKK_g%0')  (' PIAS1%0'  ' MYC%0')  (' PIAS1%0'  ' CCND1%0')  (' PIAS1%0'  ' EGR1%0')  (' PIAS1%0'  ' MMP_f%0')  (' PIAS1%0'  ' PTEN_g%0')  (' PIAS1%0'  ' RTPK_f%0')  (' PIAS1%0'  ' CTNNB1%0')  (' PIAS1%0'  'LEF1%0')  (' PIAS1%0'  'SFRP1%0')  (' PIAS1%0'  'FZD_f%0')  (' PIAS1%0'  ' CASP8%0')  (' PIAS1%0'  ' REL_f%0')  (' PIAS1%0'  ' NFKB_f%0')  (' PIAS1%0'  ' DVL_f%0')  (' PIAS1%0'  ' LRP_f%0')  (' PIAS1%0'  ' BTRC%0')  (' PIAS1%0'  ' CK1_f%0')  (' PIAS1%0'  ' AXIN1%0')  (' PIAS1%0'  ' mTORC2_c%0')  (' PIAS1%0'  ' PDPK1%0')  (' PIAS1%0'  ' MEK_f%0')  (' PIAS1%0'  ' CYCS%0')  (' PIAS1%0'  ' CASP9%0')  (' PIAS1%0'  ' GSK3_f%0')  (' PIAS1%0'  ' IRS1%0')  (' PIAS1%0'  ' MDM2%0')  (' PIAS1%0'  ' AKT_f%0')  (' PIAS1%0'  ' BCL2%0')  (' PIAS1%0'  ' RAF_f%0')  (' PIAS1%0'  ' mTORC1_c%0')  (' PIAS1%0'  ' RHEB%0')  (' PIAS1%0'  ' RTPK_g%0')  (' PIAS1%0'  ' PTEN%0')  (' PIAS1%0'  ' CASP3%0')  (' PIAS1%0'  ' PIK3CA%0')  (' PIAS1%0'  ' CREBBP%0')  (' PIAS1%0'  ' PTPN11%0')  (' PIAS1%0'  ' KRAS%0')  (' PIAS1%0'  ' MAP2K4%0')  (' PIAS1%0'  ' MAP2K7%0')  (' PIAS1%0'  ' MAPK14%0')  (' PIAS1%0'  ' JNK_f%0')  (' PIAS1%0'  ' MAP2K3%0')  (' PIAS1%0'  ' ERK_f%0')  (' PIAS1%0'  ' LIF%0')  (' PIAS1%0'  ' PPP1CA%0')  (' PIAS1%0'  ' GAB_f%0')  (' PIAS1%0'  ' SOS1%0')  (' PIAS1%0'  ' PRKCA%0')  (' PIAS1%0'  ' VAV1%0')  (' PIAS1%0'  ' PLCG1%0')  (' PIAS1%0'  ' PRKCD%0')  (' PIAS1%0'  ' RSK_f%0')  (' PIAS1%0'  ' S6K_f%0')  (' PIAS1%0'  ' PLK1%0')  (' PIAS1%0'  ' ILK%0')  (' PIAS1%0'  ' SOCS1%0')  (' PIAS1%0'  ' DUSP6%0')  (' PIAS1%0'  ' STAT3%0')  (' PIAS1%0'  ' LIMK2%0')  (' PIAS1%0'  ' EP300%0')  (' PIAS1%0'  ' STAT1%0')  (' PIAS1%0'  ' IKBKB%0')  (' PIAS1%0'  ' SRF%0')  (' PIAS1%0'  ' TRAF6%0')  (' PIAS1%0'  ' SOCS1_g%0')  (' PIAS1%0'  ' ISGF3_c%0')  (' PIAS1%0'  ' STAT2%0')  (' PIAS1%0'  ' CFLAR%0')  (' PIAS1%0'  ' SMAD2%0')  (' PIAS1%0'  ' MDM2_g%0')  (' PIAS1%0'  ' BAX%0')  (' PIAS1%0'  ' PRKACA%0')  (' PIAS1%0'  ' TGFB1%0')  (' PIAS1%0'  ' MAP3K8%0')  (' PIAS1%0'  ' TSC_f%0')  (' PIAS1%0'  ' SMAD4%0')  (' PIAS1%0'  ' BAD%0')  (' PIAS1%0'  ' MAP3K5%0')  (' PIAS1%0'  ' AKT1S1%0')  (' PIAS1%0'  ' SKI%0')  (' PIAS1%0'  ' SMAD3%0')  (' PIAS1%0'  ' MAPKAPK2%0')  (' PIAS1%0'  ' DUSP1_g%0')  (' PIAS1%0'  ' MSK_f%0')  (' PIAS1%0'  ' GRAP2%0')  (' PIAS1%0'  ' TAB_f%0')  (' PIAS1%0'  ' ATF2%0')  (' PIAS1%0'  ' SMAD5%0')  (' PIAS1%0'  ' SMAD1%0')  (' PIAS1%0'  ' FOS%0')  (' PIAS1%0'  ' JUN%0')  (' PIAS1%0'  ' MAP3K7%0')  (' PIAS1%0'  ' NLK%0')  (' PIAS1%0'  ' SMAD7_g%0')  (' PIAS1%0'  ' SMAD6_g%0')  (' PIAS1%0'  ' AP1_c%0')  (' PIAS1%0'  ' ACVR1%0')  (' PIAS1%0'  ' PTPN6%0')  (' PIAS1%0'  ' CDC42%0')  (' PIAS1%0'  ' GRB2%0')  (' PIAS1%0'  ' TGFBR1%0')  (' PIAS1%0'  ' SMURF1%0')  (' PIAS1%0'  ' SMURF2%0')  (' PIAS1%0'  ' RHOA%0')  (' PIAS1%0'  ' BMPR2%0')  (' PIAS1%0'  ' PARD6A%0')  (' PIAS1%0'  ' DAAM1%0')  (' PIAS1%0'  ' SFRP1_g%0')  (' PIAS1%0'  ' PPM1A%0')  (' PIAS1%0'  ' CFL_f%0')  (' PIAS1%0'  ' PAK1%0')  (' PIAS1%0'  ' MAP3K11%0')  (' PIAS1%0'  ' MAP3K4%0')  (' PIAS1%0'  ' LIMK1%0')  (' PIAS1%0'  ' ROCK1%0')  (' PIAS1%0'  ' ITCH%0')  (' PIAS1%0'  ' ARHGAP24%0')  (' PIAS1%0'  ' TIAM1%0')  (' PIAS1%0'  ' RND3%0')  (' PIAS1%0'  ' MAPK8IP3%0')  (' PIAS1%0'  ' MXD1%0')  (' PIAS1%0'  ' PIP3%0')  (' TRAF6%0'  ' SRC%0')  (' TRAF6%0'  ' CSK%0')  (' TRAF6%0'  ' CHUK%0')  (' TRAF6%0'  ' RAC_f%0')  (' TRAF6%0'  ' DUSP1%0')  (' TRAF6%0'  ' TGFBR2%0')  (' TRAF6%0'  ' ILR_f%0')  (' TRAF6%0'  ' SYK%0')  (' TRAF6%0'  ' IRAK1%0')  (' TRAF6%0'  ' SHC1%0')  (' TRAF6%0'  ' JAK_f%0')  (' TRAF6%0'  ' CBPp300_c%0')  (' TRAF6%0'  ' SKP2%0')  (' TRAF6%0'  ' TP53%0')  (' TRAF6%0'  ' SMAD7%0')  (' TRAF6%0'  ' SMAD6%0')  (' TRAF6%0'  ' DKK_f%0')  (' TRAF6%0'  ' FOXO_f%0')  (' TRAF6%0'  ' TCF7_f%0')  (' TRAF6%0'  ' DKK_g%0')  (' TRAF6%0'  ' MYC%0')  (' TRAF6%0'  ' CCND1%0')  (' TRAF6%0'  ' EGR1%0')  (' TRAF6%0'  ' MMP_f%0')  (' TRAF6%0'  ' PTEN_g%0')  (' TRAF6%0'  ' RTPK_f%0')  (' TRAF6%0'  ' CTNNB1%0')  (' TRAF6%0'  'LEF1%0')  (' TRAF6%0'  'SFRP1%0')  (' TRAF6%0'  'FZD_f%0')  (' TRAF6%0'  ' CASP8%0')  (' TRAF6%0'  ' REL_f%0')  (' TRAF6%0'  ' NFKB_f%0')  (' TRAF6%0'  ' DVL_f%0')  (' TRAF6%0'  ' LRP_f%0')  (' TRAF6%0'  ' BTRC%0')  (' TRAF6%0'  ' CK1_f%0')  (' TRAF6%0'  ' AXIN1%0')  (' TRAF6%0'  ' mTORC2_c%0')  (' TRAF6%0'  ' PDPK1%0')  (' TRAF6%0'  ' MEK_f%0')  (' TRAF6%0'  ' CYCS%0')  (' TRAF6%0'  ' CASP9%0')  (' TRAF6%0'  ' GSK3_f%0')  (' TRAF6%0'  ' IRS1%0')  (' TRAF6%0'  ' MDM2%0')  (' TRAF6%0'  ' AKT_f%0')  (' TRAF6%0'  ' BCL2%0')  (' TRAF6%0'  ' RAF_f%0')  (' TRAF6%0'  ' mTORC1_c%0')  (' TRAF6%0'  ' RHEB%0')  (' TRAF6%0'  ' RTPK_g%0')  (' TRAF6%0'  ' PTEN%0')  (' TRAF6%0'  ' CASP3%0')  (' TRAF6%0'  ' PIK3CA%0')  (' TRAF6%0'  ' CREBBP%0')  (' TRAF6%0'  ' PTPN11%0')  (' TRAF6%0'  ' KRAS%0')  (' TRAF6%0'  ' MAP2K4%0')  (' TRAF6%0'  ' MAP2K7%0')  (' TRAF6%0'  ' MAPK14%0')  (' TRAF6%0'  ' JNK_f%0')  (' TRAF6%0'  ' MAP2K3%0')  (' TRAF6%0'  ' ERK_f%0')  (' TRAF6%0'  ' LIF%0')  (' TRAF6%0'  ' PPP1CA%0')  (' TRAF6%0'  ' GAB_f%0')  (' TRAF6%0'  ' SOS1%0')  (' TRAF6%0'  ' PRKCA%0')  (' TRAF6%0'  ' VAV1%0')  (' TRAF6%0'  ' PLCG1%0')  (' TRAF6%0'  ' PRKCD%0')  (' TRAF6%0'  ' RSK_f%0')  (' TRAF6%0'  ' S6K_f%0')  (' TRAF6%0'  ' PLK1%0')  (' TRAF6%0'  ' ILK%0')  (' TRAF6%0'  ' SOCS1%0')  (' TRAF6%0'  ' DUSP6%0')  (' TRAF6%0'  ' STAT3%0')  (' TRAF6%0'  ' LIMK2%0')  (' TRAF6%0'  ' EP300%0')  (' TRAF6%0'  ' STAT1%0')  (' TRAF6%0'  ' IKBKB%0')  (' TRAF6%0'  ' SRF%0')  (' TRAF6%0'  ' PIAS1%0')  (' TRAF6%0'  ' SOCS1_g%0')  (' TRAF6%0'  ' ISGF3_c%0')  (' TRAF6%0'  ' STAT2%0')  (' TRAF6%0'  ' CFLAR%0')  (' TRAF6%0'  ' SMAD2%0')  (' TRAF6%0'  ' MDM2_g%0')  (' TRAF6%0'  ' BAX%0')  (' TRAF6%0'  ' PRKACA%0')  (' TRAF6%0'  ' TGFB1%0')  (' TRAF6%0'  ' MAP3K8%0')  (' TRAF6%0'  ' TSC_f%0')  (' TRAF6%0'  ' SMAD4%0')  (' TRAF6%0'  ' BAD%0')  (' TRAF6%0'  ' MAP3K5%0')  (' TRAF6%0'  ' AKT1S1%0')  (' TRAF6%0'  ' SKI%0')  (' TRAF6%0'  ' SMAD3%0')  (' TRAF6%0'  ' MAPKAPK2%0')  (' TRAF6%0'  ' DUSP1_g%0')  (' TRAF6%0'  ' MSK_f%0')  (' TRAF6%0'  ' GRAP2%0')  (' TRAF6%0'  ' TAB_f%0')  (' TRAF6%0'  ' ATF2%0')  (' TRAF6%0'  ' SMAD5%0')  (' TRAF6%0'  ' SMAD1%0')  (' TRAF6%0'  ' FOS%0')  (' TRAF6%0'  ' JUN%0')  (' TRAF6%0'  ' MAP3K7%0')  (' TRAF6%0'  ' NLK%0')  (' TRAF6%0'  ' SMAD7_g%0')  (' TRAF6%0'  ' SMAD6_g%0')  (' TRAF6%0'  ' AP1_c%0')  (' TRAF6%0'  ' ACVR1%0')  (' TRAF6%0'  ' PTPN6%0')  (' TRAF6%0'  ' CDC42%0')  (' TRAF6%0'  ' GRB2%0')  (' TRAF6%0'  ' TGFBR1%0')  (' TRAF6%0'  ' SMURF1%0')  (' TRAF6%0'  ' SMURF2%0')  (' TRAF6%0'  ' RHOA%0')  (' TRAF6%0'  ' BMPR2%0')  (' TRAF6%0'  ' PARD6A%0')  (' TRAF6%0'  ' DAAM1%0')  (' TRAF6%0'  ' SFRP1_g%0')  (' TRAF6%0'  ' PPM1A%0')  (' TRAF6%0'  ' CFL_f%0')  (' TRAF6%0'  ' PAK1%0')  (' TRAF6%0'  ' MAP3K11%0')  (' TRAF6%0'  ' MAP3K4%0')  (' TRAF6%0'  ' LIMK1%0')  (' TRAF6%0'  ' ROCK1%0')  (' TRAF6%0'  ' ITCH%0')  (' TRAF6%0'  ' ARHGAP24%0')  (' TRAF6%0'  ' TIAM1%0')  (' TRAF6%0'  ' RND3%0')  (' TRAF6%0'  ' MAPK8IP3%0')  (' TRAF6%0'  ' MXD1%0')  (' TRAF6%0'  ' PIP3%0')  (' SOCS1_g%0'  ' SRC%0')  (' SOCS1_g%0'  ' CSK%0')  (' SOCS1_g%0'  ' CHUK%0')  (' SOCS1_g%0'  ' RAC_f%0')  (' SOCS1_g%0'  ' DUSP1%0')  (' SOCS1_g%0'  ' TGFBR2%0')  (' SOCS1_g%0'  ' ILR_f%0')  (' SOCS1_g%0'  ' SYK%0')  (' SOCS1_g%0'  ' IRAK1%0')  (' SOCS1_g%0'  ' SHC1%0')  (' SOCS1_g%0'  ' JAK_f%0')  (' SOCS1_g%0'  ' CBPp300_c%0')  (' SOCS1_g%0'  ' SKP2%0')  (' SOCS1_g%0'  ' TP53%0')  (' SOCS1_g%0'  ' SMAD7%0')  (' SOCS1_g%0'  ' SMAD6%0')  (' SOCS1_g%0'  ' DKK_f%0')  (' SOCS1_g%0'  ' FOXO_f%0')  (' SOCS1_g%0'  ' TCF7_f%0')  (' SOCS1_g%0'  ' DKK_g%0')  (' SOCS1_g%0'  ' MYC%0')  (' SOCS1_g%0'  ' CCND1%0')  (' SOCS1_g%0'  ' EGR1%0')  (' SOCS1_g%0'  ' MMP_f%0')  (' SOCS1_g%0'  ' PTEN_g%0')  (' SOCS1_g%0'  ' RTPK_f%0')  (' SOCS1_g%0'  ' CTNNB1%0')  (' SOCS1_g%0'  'LEF1%0')  (' SOCS1_g%0'  'SFRP1%0')  (' SOCS1_g%0'  'FZD_f%0')  (' SOCS1_g%0'  ' CASP8%0')  (' SOCS1_g%0'  ' REL_f%0')  (' SOCS1_g%0'  ' NFKB_f%0')  (' SOCS1_g%0'  ' DVL_f%0')  (' SOCS1_g%0'  ' LRP_f%0')  (' SOCS1_g%0'  ' BTRC%0')  (' SOCS1_g%0'  ' CK1_f%0')  (' SOCS1_g%0'  ' AXIN1%0')  (' SOCS1_g%0'  ' mTORC2_c%0')  (' SOCS1_g%0'  ' PDPK1%0')  (' SOCS1_g%0'  ' MEK_f%0')  (' SOCS1_g%0'  ' CYCS%0')  (' SOCS1_g%0'  ' CASP9%0')  (' SOCS1_g%0'  ' GSK3_f%0')  (' SOCS1_g%0'  ' IRS1%0')  (' SOCS1_g%0'  ' MDM2%0')  (' SOCS1_g%0'  ' AKT_f%0')  (' SOCS1_g%0'  ' BCL2%0')  (' SOCS1_g%0'  ' RAF_f%0')  (' SOCS1_g%0'  ' mTORC1_c%0')  (' SOCS1_g%0'  ' RHEB%0')  (' SOCS1_g%0'  ' RTPK_g%0')  (' SOCS1_g%0'  ' PTEN%0')  (' SOCS1_g%0'  ' CASP3%0')  (' SOCS1_g%0'  ' PIK3CA%0')  (' SOCS1_g%0'  ' CREBBP%0')  (' SOCS1_g%0'  ' PTPN11%0')  (' SOCS1_g%0'  ' KRAS%0')  (' SOCS1_g%0'  ' MAP2K4%0')  (' SOCS1_g%0'  ' MAP2K7%0')  (' SOCS1_g%0'  ' MAPK14%0')  (' SOCS1_g%0'  ' JNK_f%0')  (' SOCS1_g%0'  ' MAP2K3%0')  (' SOCS1_g%0'  ' ERK_f%0')  (' SOCS1_g%0'  ' LIF%0')  (' SOCS1_g%0'  ' PPP1CA%0')  (' SOCS1_g%0'  ' GAB_f%0')  (' SOCS1_g%0'  ' SOS1%0')  (' SOCS1_g%0'  ' PRKCA%0')  (' SOCS1_g%0'  ' VAV1%0')  (' SOCS1_g%0'  ' PLCG1%0')  (' SOCS1_g%0'  ' PRKCD%0')  (' SOCS1_g%0'  ' RSK_f%0')  (' SOCS1_g%0'  ' S6K_f%0')  (' SOCS1_g%0'  ' PLK1%0')  (' SOCS1_g%0'  ' ILK%0')  (' SOCS1_g%0'  ' SOCS1%0')  (' SOCS1_g%0'  ' DUSP6%0')  (' SOCS1_g%0'  ' STAT3%0')  (' SOCS1_g%0'  ' LIMK2%0')  (' SOCS1_g%0'  ' EP300%0')  (' SOCS1_g%0'  ' STAT1%0')  (' SOCS1_g%0'  ' IKBKB%0')  (' SOCS1_g%0'  ' SRF%0')  (' SOCS1_g%0'  ' PIAS1%0')  (' SOCS1_g%0'  ' TRAF6%0')  (' SOCS1_g%0'  ' ISGF3_c%0')  (' SOCS1_g%0'  ' STAT2%0')  (' SOCS1_g%0'  ' CFLAR%0')  (' SOCS1_g%0'  ' SMAD2%0')  (' SOCS1_g%0'  ' MDM2_g%0')  (' SOCS1_g%0'  ' BAX%0')  (' SOCS1_g%0'  ' PRKACA%0')  (' SOCS1_g%0'  ' TGFB1%0')  (' SOCS1_g%0'  ' MAP3K8%0')  (' SOCS1_g%0'  ' TSC_f%0')  (' SOCS1_g%0'  ' SMAD4%0')  (' SOCS1_g%0'  ' BAD%0')  (' SOCS1_g%0'  ' MAP3K5%0')  (' SOCS1_g%0'  ' AKT1S1%0')  (' SOCS1_g%0'  ' SKI%0')  (' SOCS1_g%0'  ' SMAD3%0')  (' SOCS1_g%0'  ' MAPKAPK2%0')  (' SOCS1_g%0'  ' DUSP1_g%0')  (' SOCS1_g%0'  ' MSK_f%0')  (' SOCS1_g%0'  ' GRAP2%0')  (' SOCS1_g%0'  ' TAB_f%0')  (' SOCS1_g%0'  ' ATF2%0')  (' SOCS1_g%0'  ' SMAD5%0')  (' SOCS1_g%0'  ' SMAD1%0')  (' SOCS1_g%0'  ' FOS%0')  (' SOCS1_g%0'  ' JUN%0')  (' SOCS1_g%0'  ' MAP3K7%0')  (' SOCS1_g%0'  ' NLK%0')  (' SOCS1_g%0'  ' SMAD7_g%0')  (' SOCS1_g%0'  ' SMAD6_g%0')  (' SOCS1_g%0'  ' AP1_c%0')  (' SOCS1_g%0'  ' ACVR1%0')  (' SOCS1_g%0'  ' PTPN6%0')  (' SOCS1_g%0'  ' CDC42%0')  (' SOCS1_g%0'  ' GRB2%0')  (' SOCS1_g%0'  ' TGFBR1%0')  (' SOCS1_g%0'  ' SMURF1%0')  (' SOCS1_g%0'  ' SMURF2%0')  (' SOCS1_g%0'  ' RHOA%0')  (' SOCS1_g%0'  ' BMPR2%0')  (' SOCS1_g%0'  ' PARD6A%0')  (' SOCS1_g%0'  ' DAAM1%0')  (' SOCS1_g%0'  ' SFRP1_g%0')  (' SOCS1_g%0'  ' PPM1A%0')  (' SOCS1_g%0'  ' CFL_f%0')  (' SOCS1_g%0'  ' PAK1%0')  (' SOCS1_g%0'  ' MAP3K11%0')  (' SOCS1_g%0'  ' MAP3K4%0')  (' SOCS1_g%0'  ' LIMK1%0')  (' SOCS1_g%0'  ' ROCK1%0')  (' SOCS1_g%0'  ' ITCH%0')  (' SOCS1_g%0'  ' ARHGAP24%0')  (' SOCS1_g%0'  ' TIAM1%0')  (' SOCS1_g%0'  ' RND3%0')  (' SOCS1_g%0'  ' MAPK8IP3%0')  (' SOCS1_g%0'  ' MXD1%0')  (' SOCS1_g%0'  ' PIP3%0')  (' ISGF3_c%0'  ' SRC%0')  (' ISGF3_c%0'  ' CSK%0')  (' ISGF3_c%0'  ' CHUK%0')  (' ISGF3_c%0'  ' RAC_f%0')  (' ISGF3_c%0'  ' DUSP1%0')  (' ISGF3_c%0'  ' TGFBR2%0')  (' ISGF3_c%0'  ' ILR_f%0')  (' ISGF3_c%0'  ' SYK%0')  (' ISGF3_c%0'  ' IRAK1%0')  (' ISGF3_c%0'  ' SHC1%0')  (' ISGF3_c%0'  ' JAK_f%0')  (' ISGF3_c%0'  ' CBPp300_c%0')  (' ISGF3_c%0'  ' SKP2%0')  (' ISGF3_c%0'  ' TP53%0')  (' ISGF3_c%0'  ' SMAD7%0')  (' ISGF3_c%0'  ' SMAD6%0')  (' ISGF3_c%0'  ' DKK_f%0')  (' ISGF3_c%0'  ' FOXO_f%0')  (' ISGF3_c%0'  ' TCF7_f%0')  (' ISGF3_c%0'  ' DKK_g%0')  (' ISGF3_c%0'  ' MYC%0')  (' ISGF3_c%0'  ' CCND1%0')  (' ISGF3_c%0'  ' EGR1%0')  (' ISGF3_c%0'  ' MMP_f%0')  (' ISGF3_c%0'  ' PTEN_g%0')  (' ISGF3_c%0'  ' RTPK_f%0')  (' ISGF3_c%0'  ' CTNNB1%0')  (' ISGF3_c%0'  'LEF1%0')  (' ISGF3_c%0'  'SFRP1%0')  (' ISGF3_c%0'  'FZD_f%0')  (' ISGF3_c%0'  ' CASP8%0')  (' ISGF3_c%0'  ' REL_f%0')  (' ISGF3_c%0'  ' NFKB_f%0')  (' ISGF3_c%0'  ' DVL_f%0')  (' ISGF3_c%0'  ' LRP_f%0')  (' ISGF3_c%0'  ' BTRC%0')  (' ISGF3_c%0'  ' CK1_f%0')  (' ISGF3_c%0'  ' AXIN1%0')  (' ISGF3_c%0'  ' mTORC2_c%0')  (' ISGF3_c%0'  ' PDPK1%0')  (' ISGF3_c%0'  ' MEK_f%0')  (' ISGF3_c%0'  ' CYCS%0')  (' ISGF3_c%0'  ' CASP9%0')  (' ISGF3_c%0'  ' GSK3_f%0')  (' ISGF3_c%0'  ' IRS1%0')  (' ISGF3_c%0'  ' MDM2%0')  (' ISGF3_c%0'  ' AKT_f%0')  (' ISGF3_c%0'  ' BCL2%0')  (' ISGF3_c%0'  ' RAF_f%0')  (' ISGF3_c%0'  ' mTORC1_c%0')  (' ISGF3_c%0'  ' RHEB%0')  (' ISGF3_c%0'  ' RTPK_g%0')  (' ISGF3_c%0'  ' PTEN%0')  (' ISGF3_c%0'  ' CASP3%0')  (' ISGF3_c%0'  ' PIK3CA%0')  (' ISGF3_c%0'  ' CREBBP%0')  (' ISGF3_c%0'  ' PTPN11%0')  (' ISGF3_c%0'  ' KRAS%0')  (' ISGF3_c%0'  ' MAP2K4%0')  (' ISGF3_c%0'  ' MAP2K7%0')  (' ISGF3_c%0'  ' MAPK14%0')  (' ISGF3_c%0'  ' JNK_f%0')  (' ISGF3_c%0'  ' MAP2K3%0')  (' ISGF3_c%0'  ' ERK_f%0')  (' ISGF3_c%0'  ' LIF%0')  (' ISGF3_c%0'  ' PPP1CA%0')  (' ISGF3_c%0'  ' GAB_f%0')  (' ISGF3_c%0'  ' SOS1%0')  (' ISGF3_c%0'  ' PRKCA%0')  (' ISGF3_c%0'  ' VAV1%0')  (' ISGF3_c%0'  ' PLCG1%0')  (' ISGF3_c%0'  ' PRKCD%0')  (' ISGF3_c%0'  ' RSK_f%0')  (' ISGF3_c%0'  ' S6K_f%0')  (' ISGF3_c%0'  ' PLK1%0')  (' ISGF3_c%0'  ' ILK%0')  (' ISGF3_c%0'  ' SOCS1%0')  (' ISGF3_c%0'  ' DUSP6%0')  (' ISGF3_c%0'  ' STAT3%0')  (' ISGF3_c%0'  ' LIMK2%0')  (' ISGF3_c%0'  ' EP300%0')  (' ISGF3_c%0'  ' STAT1%0')  (' ISGF3_c%0'  ' IKBKB%0')  (' ISGF3_c%0'  ' SRF%0')  (' ISGF3_c%0'  ' PIAS1%0')  (' ISGF3_c%0'  ' TRAF6%0')  (' ISGF3_c%0'  ' SOCS1_g%0')  (' ISGF3_c%0'  ' STAT2%0')  (' ISGF3_c%0'  ' CFLAR%0')  (' ISGF3_c%0'  ' SMAD2%0')  (' ISGF3_c%0'  ' MDM2_g%0')  (' ISGF3_c%0'  ' BAX%0')  (' ISGF3_c%0'  ' PRKACA%0')  (' ISGF3_c%0'  ' TGFB1%0')  (' ISGF3_c%0'  ' MAP3K8%0')  (' ISGF3_c%0'  ' TSC_f%0')  (' ISGF3_c%0'  ' SMAD4%0')  (' ISGF3_c%0'  ' BAD%0')  (' ISGF3_c%0'  ' MAP3K5%0')  (' ISGF3_c%0'  ' AKT1S1%0')  (' ISGF3_c%0'  ' SKI%0')  (' ISGF3_c%0'  ' SMAD3%0')  (' ISGF3_c%0'  ' MAPKAPK2%0')  (' ISGF3_c%0'  ' DUSP1_g%0')  (' ISGF3_c%0'  ' MSK_f%0')  (' ISGF3_c%0'  ' GRAP2%0')  (' ISGF3_c%0'  ' TAB_f%0')  (' ISGF3_c%0'  ' ATF2%0')  (' ISGF3_c%0'  ' SMAD5%0')  (' ISGF3_c%0'  ' SMAD1%0')  (' ISGF3_c%0'  ' FOS%0')  (' ISGF3_c%0'  ' JUN%0')  (' ISGF3_c%0'  ' MAP3K7%0')  (' ISGF3_c%0'  ' NLK%0')  (' ISGF3_c%0'  ' SMAD7_g%0')  (' ISGF3_c%0'  ' SMAD6_g%0')  (' ISGF3_c%0'  ' AP1_c%0')  (' ISGF3_c%0'  ' ACVR1%0')  (' ISGF3_c%0'  ' PTPN6%0')  (' ISGF3_c%0'  ' CDC42%0')  (' ISGF3_c%0'  ' GRB2%0')  (' ISGF3_c%0'  ' TGFBR1%0')  (' ISGF3_c%0'  ' SMURF1%0')  (' ISGF3_c%0'  ' SMURF2%0')  (' ISGF3_c%0'  ' RHOA%0')  (' ISGF3_c%0'  ' BMPR2%0')  (' ISGF3_c%0'  ' PARD6A%0')  (' ISGF3_c%0'  ' DAAM1%0')  (' ISGF3_c%0'  ' SFRP1_g%0')  (' ISGF3_c%0'  ' PPM1A%0')  (' ISGF3_c%0'  ' CFL_f%0')  (' ISGF3_c%0'  ' PAK1%0')  (' ISGF3_c%0'  ' MAP3K11%0')  (' ISGF3_c%0'  ' MAP3K4%0')  (' ISGF3_c%0'  ' LIMK1%0')  (' ISGF3_c%0'  ' ROCK1%0')  (' ISGF3_c%0'  ' ITCH%0')  (' ISGF3_c%0'  ' ARHGAP24%0')  (' ISGF3_c%0'  ' TIAM1%0')  (' ISGF3_c%0'  ' RND3%0')  (' ISGF3_c%0'  ' MAPK8IP3%0')  (' ISGF3_c%0'  ' MXD1%0')  (' ISGF3_c%0'  ' PIP3%0')  (' STAT2%0'  ' SRC%0')  (' STAT2%0'  ' CSK%0')  (' STAT2%0'  ' CHUK%0')  (' STAT2%0'  ' RAC_f%0')  (' STAT2%0'  ' DUSP1%0')  (' STAT2%0'  ' TGFBR2%0')  (' STAT2%0'  ' ILR_f%0')  (' STAT2%0'  ' SYK%0')  (' STAT2%0'  ' IRAK1%0')  (' STAT2%0'  ' SHC1%0')  (' STAT2%0'  ' JAK_f%0')  (' STAT2%0'  ' CBPp300_c%0')  (' STAT2%0'  ' SKP2%0')  (' STAT2%0'  ' TP53%0')  (' STAT2%0'  ' SMAD7%0')  (' STAT2%0'  ' SMAD6%0')  (' STAT2%0'  ' DKK_f%0')  (' STAT2%0'  ' FOXO_f%0')  (' STAT2%0'  ' TCF7_f%0')  (' STAT2%0'  ' DKK_g%0')  (' STAT2%0'  ' MYC%0')  (' STAT2%0'  ' CCND1%0')  (' STAT2%0'  ' EGR1%0')  (' STAT2%0'  ' MMP_f%0')  (' STAT2%0'  ' PTEN_g%0')  (' STAT2%0'  ' RTPK_f%0')  (' STAT2%0'  ' CTNNB1%0')  (' STAT2%0'  'LEF1%0')  (' STAT2%0'  'SFRP1%0')  (' STAT2%0'  'FZD_f%0')  (' STAT2%0'  ' CASP8%0')  (' STAT2%0'  ' REL_f%0')  (' STAT2%0'  ' NFKB_f%0')  (' STAT2%0'  ' DVL_f%0')  (' STAT2%0'  ' LRP_f%0')  (' STAT2%0'  ' BTRC%0')  (' STAT2%0'  ' CK1_f%0')  (' STAT2%0'  ' AXIN1%0')  (' STAT2%0'  ' mTORC2_c%0')  (' STAT2%0'  ' PDPK1%0')  (' STAT2%0'  ' MEK_f%0')  (' STAT2%0'  ' CYCS%0')  (' STAT2%0'  ' CASP9%0')  (' STAT2%0'  ' GSK3_f%0')  (' STAT2%0'  ' IRS1%0')  (' STAT2%0'  ' MDM2%0')  (' STAT2%0'  ' AKT_f%0')  (' STAT2%0'  ' BCL2%0')  (' STAT2%0'  ' RAF_f%0')  (' STAT2%0'  ' mTORC1_c%0')  (' STAT2%0'  ' RHEB%0')  (' STAT2%0'  ' RTPK_g%0')  (' STAT2%0'  ' PTEN%0')  (' STAT2%0'  ' CASP3%0')  (' STAT2%0'  ' PIK3CA%0')  (' STAT2%0'  ' CREBBP%0')  (' STAT2%0'  ' PTPN11%0')  (' STAT2%0'  ' KRAS%0')  (' STAT2%0'  ' MAP2K4%0')  (' STAT2%0'  ' MAP2K7%0')  (' STAT2%0'  ' MAPK14%0')  (' STAT2%0'  ' JNK_f%0')  (' STAT2%0'  ' MAP2K3%0')  (' STAT2%0'  ' ERK_f%0')  (' STAT2%0'  ' LIF%0')  (' STAT2%0'  ' PPP1CA%0')  (' STAT2%0'  ' GAB_f%0')  (' STAT2%0'  ' SOS1%0')  (' STAT2%0'  ' PRKCA%0')  (' STAT2%0'  ' VAV1%0')  (' STAT2%0'  ' PLCG1%0')  (' STAT2%0'  ' PRKCD%0')  (' STAT2%0'  ' RSK_f%0')  (' STAT2%0'  ' S6K_f%0')  (' STAT2%0'  ' PLK1%0')  (' STAT2%0'  ' ILK%0')  (' STAT2%0'  ' SOCS1%0')  (' STAT2%0'  ' DUSP6%0')  (' STAT2%0'  ' STAT3%0')  (' STAT2%0'  ' LIMK2%0')  (' STAT2%0'  ' EP300%0')  (' STAT2%0'  ' STAT1%0')  (' STAT2%0'  ' IKBKB%0')  (' STAT2%0'  ' SRF%0')  (' STAT2%0'  ' PIAS1%0')  (' STAT2%0'  ' TRAF6%0')  (' STAT2%0'  ' SOCS1_g%0')  (' STAT2%0'  ' ISGF3_c%0')  (' STAT2%0'  ' CFLAR%0')  (' STAT2%0'  ' SMAD2%0')  (' STAT2%0'  ' MDM2_g%0')  (' STAT2%0'  ' BAX%0')  (' STAT2%0'  ' PRKACA%0')  (' STAT2%0'  ' TGFB1%0')  (' STAT2%0'  ' MAP3K8%0')  (' STAT2%0'  ' TSC_f%0')  (' STAT2%0'  ' SMAD4%0')  (' STAT2%0'  ' BAD%0')  (' STAT2%0'  ' MAP3K5%0')  (' STAT2%0'  ' AKT1S1%0')  (' STAT2%0'  ' SKI%0')  (' STAT2%0'  ' SMAD3%0')  (' STAT2%0'  ' MAPKAPK2%0')  (' STAT2%0'  ' DUSP1_g%0')  (' STAT2%0'  ' MSK_f%0')  (' STAT2%0'  ' GRAP2%0')  (' STAT2%0'  ' TAB_f%0')  (' STAT2%0'  ' ATF2%0')  (' STAT2%0'  ' SMAD5%0')  (' STAT2%0'  ' SMAD1%0')  (' STAT2%0'  ' FOS%0')  (' STAT2%0'  ' JUN%0')  (' STAT2%0'  ' MAP3K7%0')  (' STAT2%0'  ' NLK%0')  (' STAT2%0'  ' SMAD7_g%0')  (' STAT2%0'  ' SMAD6_g%0')  (' STAT2%0'  ' AP1_c%0')  (' STAT2%0'  ' ACVR1%0')  (' STAT2%0'  ' PTPN6%0')  (' STAT2%0'  ' CDC42%0')  (' STAT2%0'  ' GRB2%0')  (' STAT2%0'  ' TGFBR1%0')  (' STAT2%0'  ' SMURF1%0')  (' STAT2%0'  ' SMURF2%0')  (' STAT2%0'  ' RHOA%0')  (' STAT2%0'  ' BMPR2%0')  (' STAT2%0'  ' PARD6A%0')  (' STAT2%0'  ' DAAM1%0')  (' STAT2%0'  ' SFRP1_g%0')  (' STAT2%0'  ' PPM1A%0')  (' STAT2%0'  ' CFL_f%0')  (' STAT2%0'  ' PAK1%0')  (' STAT2%0'  ' MAP3K11%0')  (' STAT2%0'  ' MAP3K4%0')  (' STAT2%0'  ' LIMK1%0')  (' STAT2%0'  ' ROCK1%0')  (' STAT2%0'  ' ITCH%0')  (' STAT2%0'  ' ARHGAP24%0')  (' STAT2%0'  ' TIAM1%0')  (' STAT2%0'  ' RND3%0')  (' STAT2%0'  ' MAPK8IP3%0')  (' STAT2%0'  ' MXD1%0')  (' STAT2%0'  ' PIP3%0')  (' CFLAR%0'  ' SRC%0')  (' CFLAR%0'  ' CSK%0')  (' CFLAR%0'  ' CHUK%0')  (' CFLAR%0'  ' RAC_f%0')  (' CFLAR%0'  ' DUSP1%0')  (' CFLAR%0'  ' TGFBR2%0')  (' CFLAR%0'  ' ILR_f%0')  (' CFLAR%0'  ' SYK%0')  (' CFLAR%0'  ' IRAK1%0')  (' CFLAR%0'  ' SHC1%0')  (' CFLAR%0'  ' JAK_f%0')  (' CFLAR%0'  ' CBPp300_c%0')  (' CFLAR%0'  ' SKP2%0')  (' CFLAR%0'  ' TP53%0')  (' CFLAR%0'  ' SMAD7%0')  (' CFLAR%0'  ' SMAD6%0')  (' CFLAR%0'  ' DKK_f%0')  (' CFLAR%0'  ' FOXO_f%0')  (' CFLAR%0'  ' TCF7_f%0')  (' CFLAR%0'  ' DKK_g%0')  (' CFLAR%0'  ' MYC%0')  (' CFLAR%0'  ' CCND1%0')  (' CFLAR%0'  ' EGR1%0')  (' CFLAR%0'  ' MMP_f%0')  (' CFLAR%0'  ' PTEN_g%0')  (' CFLAR%0'  ' RTPK_f%0')  (' CFLAR%0'  ' CTNNB1%0')  (' CFLAR%0'  'LEF1%0')  (' CFLAR%0'  'SFRP1%0')  (' CFLAR%0'  'FZD_f%0')  (' CFLAR%0'  ' CASP8%0')  (' CFLAR%0'  ' REL_f%0')  (' CFLAR%0'  ' NFKB_f%0')  (' CFLAR%0'  ' DVL_f%0')  (' CFLAR%0'  ' LRP_f%0')  (' CFLAR%0'  ' BTRC%0')  (' CFLAR%0'  ' CK1_f%0')  (' CFLAR%0'  ' AXIN1%0')  (' CFLAR%0'  ' mTORC2_c%0')  (' CFLAR%0'  ' PDPK1%0')  (' CFLAR%0'  ' MEK_f%0')  (' CFLAR%0'  ' CYCS%0')  (' CFLAR%0'  ' CASP9%0')  (' CFLAR%0'  ' GSK3_f%0')  (' CFLAR%0'  ' IRS1%0')  (' CFLAR%0'  ' MDM2%0')  (' CFLAR%0'  ' AKT_f%0')  (' CFLAR%0'  ' BCL2%0')  (' CFLAR%0'  ' RAF_f%0')  (' CFLAR%0'  ' mTORC1_c%0')  (' CFLAR%0'  ' RHEB%0')  (' CFLAR%0'  ' RTPK_g%0')  (' CFLAR%0'  ' PTEN%0')  (' CFLAR%0'  ' CASP3%0')  (' CFLAR%0'  ' PIK3CA%0')  (' CFLAR%0'  ' CREBBP%0')  (' CFLAR%0'  ' PTPN11%0')  (' CFLAR%0'  ' KRAS%0')  (' CFLAR%0'  ' MAP2K4%0')  (' CFLAR%0'  ' MAP2K7%0')  (' CFLAR%0'  ' MAPK14%0')  (' CFLAR%0'  ' JNK_f%0')  (' CFLAR%0'  ' MAP2K3%0')  (' CFLAR%0'  ' ERK_f%0')  (' CFLAR%0'  ' LIF%0')  (' CFLAR%0'  ' PPP1CA%0')  (' CFLAR%0'  ' GAB_f%0')  (' CFLAR%0'  ' SOS1%0')  (' CFLAR%0'  ' PRKCA%0')  (' CFLAR%0'  ' VAV1%0')  (' CFLAR%0'  ' PLCG1%0')  (' CFLAR%0'  ' PRKCD%0')  (' CFLAR%0'  ' RSK_f%0')  (' CFLAR%0'  ' S6K_f%0')  (' CFLAR%0'  ' PLK1%0')  (' CFLAR%0'  ' ILK%0')  (' CFLAR%0'  ' SOCS1%0')  (' CFLAR%0'  ' DUSP6%0')  (' CFLAR%0'  ' STAT3%0')  (' CFLAR%0'  ' LIMK2%0')  (' CFLAR%0'  ' EP300%0')  (' CFLAR%0'  ' STAT1%0')  (' CFLAR%0'  ' IKBKB%0')  (' CFLAR%0'  ' SRF%0')  (' CFLAR%0'  ' PIAS1%0')  (' CFLAR%0'  ' TRAF6%0')  (' CFLAR%0'  ' SOCS1_g%0')  (' CFLAR%0'  ' ISGF3_c%0')  (' CFLAR%0'  ' STAT2%0')  (' CFLAR%0'  ' SMAD2%0')  (' CFLAR%0'  ' MDM2_g%0')  (' CFLAR%0'  ' BAX%0')  (' CFLAR%0'  ' PRKACA%0')  (' CFLAR%0'  ' TGFB1%0')  (' CFLAR%0'  ' MAP3K8%0')  (' CFLAR%0'  ' TSC_f%0')  (' CFLAR%0'  ' SMAD4%0')  (' CFLAR%0'  ' BAD%0')  (' CFLAR%0'  ' MAP3K5%0')  (' CFLAR%0'  ' AKT1S1%0')  (' CFLAR%0'  ' SKI%0')  (' CFLAR%0'  ' SMAD3%0')  (' CFLAR%0'  ' MAPKAPK2%0')  (' CFLAR%0'  ' DUSP1_g%0')  (' CFLAR%0'  ' MSK_f%0')  (' CFLAR%0'  ' GRAP2%0')  (' CFLAR%0'  ' TAB_f%0')  (' CFLAR%0'  ' ATF2%0')  (' CFLAR%0'  ' SMAD5%0')  (' CFLAR%0'  ' SMAD1%0')  (' CFLAR%0'  ' FOS%0')  (' CFLAR%0'  ' JUN%0')  (' CFLAR%0'  ' MAP3K7%0')  (' CFLAR%0'  ' NLK%0')  (' CFLAR%0'  ' SMAD7_g%0')  (' CFLAR%0'  ' SMAD6_g%0')  (' CFLAR%0'  ' AP1_c%0')  (' CFLAR%0'  ' ACVR1%0')  (' CFLAR%0'  ' PTPN6%0')  (' CFLAR%0'  ' CDC42%0')  (' CFLAR%0'  ' GRB2%0')  (' CFLAR%0'  ' TGFBR1%0')  (' CFLAR%0'  ' SMURF1%0')  (' CFLAR%0'  ' SMURF2%0')  (' CFLAR%0'  ' RHOA%0')  (' CFLAR%0'  ' BMPR2%0')  (' CFLAR%0'  ' PARD6A%0')  (' CFLAR%0'  ' DAAM1%0')  (' CFLAR%0'  ' SFRP1_g%0')  (' CFLAR%0'  ' PPM1A%0')  (' CFLAR%0'  ' CFL_f%0')  (' CFLAR%0'  ' PAK1%0')  (' CFLAR%0'  ' MAP3K11%0')  (' CFLAR%0'  ' MAP3K4%0')  (' CFLAR%0'  ' LIMK1%0')  (' CFLAR%0'  ' ROCK1%0')  (' CFLAR%0'  ' ITCH%0')  (' CFLAR%0'  ' ARHGAP24%0')  (' CFLAR%0'  ' TIAM1%0')  (' CFLAR%0'  ' RND3%0')  (' CFLAR%0'  ' MAPK8IP3%0')  (' CFLAR%0'  ' MXD1%0')  (' CFLAR%0'  ' PIP3%0')  (' SMAD2%0'  ' SRC%0')  (' SMAD2%0'  ' CSK%0')  (' SMAD2%0'  ' CHUK%0')  (' SMAD2%0'  ' RAC_f%0')  (' SMAD2%0'  ' DUSP1%0')  (' SMAD2%0'  ' TGFBR2%0')  (' SMAD2%0'  ' ILR_f%0')  (' SMAD2%0'  ' SYK%0')  (' SMAD2%0'  ' IRAK1%0')  (' SMAD2%0'  ' SHC1%0')  (' SMAD2%0'  ' JAK_f%0')  (' SMAD2%0'  ' CBPp300_c%0')  (' SMAD2%0'  ' SKP2%0')  (' SMAD2%0'  ' TP53%0')  (' SMAD2%0'  ' SMAD7%0')  (' SMAD2%0'  ' SMAD6%0')  (' SMAD2%0'  ' DKK_f%0')  (' SMAD2%0'  ' FOXO_f%0')  (' SMAD2%0'  ' TCF7_f%0')  (' SMAD2%0'  ' DKK_g%0')  (' SMAD2%0'  ' MYC%0')  (' SMAD2%0'  ' CCND1%0')  (' SMAD2%0'  ' EGR1%0')  (' SMAD2%0'  ' MMP_f%0')  (' SMAD2%0'  ' PTEN_g%0')  (' SMAD2%0'  ' RTPK_f%0')  (' SMAD2%0'  ' CTNNB1%0')  (' SMAD2%0'  'LEF1%0')  (' SMAD2%0'  'SFRP1%0')  (' SMAD2%0'  'FZD_f%0')  (' SMAD2%0'  ' CASP8%0')  (' SMAD2%0'  ' REL_f%0')  (' SMAD2%0'  ' NFKB_f%0')  (' SMAD2%0'  ' DVL_f%0')  (' SMAD2%0'  ' LRP_f%0')  (' SMAD2%0'  ' BTRC%0')  (' SMAD2%0'  ' CK1_f%0')  (' SMAD2%0'  ' AXIN1%0')  (' SMAD2%0'  ' mTORC2_c%0')  (' SMAD2%0'  ' PDPK1%0')  (' SMAD2%0'  ' MEK_f%0')  (' SMAD2%0'  ' CYCS%0')  (' SMAD2%0'  ' CASP9%0')  (' SMAD2%0'  ' GSK3_f%0')  (' SMAD2%0'  ' IRS1%0')  (' SMAD2%0'  ' MDM2%0')  (' SMAD2%0'  ' AKT_f%0')  (' SMAD2%0'  ' BCL2%0')  (' SMAD2%0'  ' RAF_f%0')  (' SMAD2%0'  ' mTORC1_c%0')  (' SMAD2%0'  ' RHEB%0')  (' SMAD2%0'  ' RTPK_g%0')  (' SMAD2%0'  ' PTEN%0')  (' SMAD2%0'  ' CASP3%0')  (' SMAD2%0'  ' PIK3CA%0')  (' SMAD2%0'  ' CREBBP%0')  (' SMAD2%0'  ' PTPN11%0')  (' SMAD2%0'  ' KRAS%0')  (' SMAD2%0'  ' MAP2K4%0')  (' SMAD2%0'  ' MAP2K7%0')  (' SMAD2%0'  ' MAPK14%0')  (' SMAD2%0'  ' JNK_f%0')  (' SMAD2%0'  ' MAP2K3%0')  (' SMAD2%0'  ' ERK_f%0')  (' SMAD2%0'  ' LIF%0')  (' SMAD2%0'  ' PPP1CA%0')  (' SMAD2%0'  ' GAB_f%0')  (' SMAD2%0'  ' SOS1%0')  (' SMAD2%0'  ' PRKCA%0')  (' SMAD2%0'  ' VAV1%0')  (' SMAD2%0'  ' PLCG1%0')  (' SMAD2%0'  ' PRKCD%0')  (' SMAD2%0'  ' RSK_f%0')  (' SMAD2%0'  ' S6K_f%0')  (' SMAD2%0'  ' PLK1%0')  (' SMAD2%0'  ' ILK%0')  (' SMAD2%0'  ' SOCS1%0')  (' SMAD2%0'  ' DUSP6%0')  (' SMAD2%0'  ' STAT3%0')  (' SMAD2%0'  ' LIMK2%0')  (' SMAD2%0'  ' EP300%0')  (' SMAD2%0'  ' STAT1%0')  (' SMAD2%0'  ' IKBKB%0')  (' SMAD2%0'  ' SRF%0')  (' SMAD2%0'  ' PIAS1%0')  (' SMAD2%0'  ' TRAF6%0')  (' SMAD2%0'  ' SOCS1_g%0')  (' SMAD2%0'  ' ISGF3_c%0')  (' SMAD2%0'  ' STAT2%0')  (' SMAD2%0'  ' CFLAR%0')  (' SMAD2%0'  ' MDM2_g%0')  (' SMAD2%0'  ' BAX%0')  (' SMAD2%0'  ' PRKACA%0')  (' SMAD2%0'  ' TGFB1%0')  (' SMAD2%0'  ' MAP3K8%0')  (' SMAD2%0'  ' TSC_f%0')  (' SMAD2%0'  ' SMAD4%0')  (' SMAD2%0'  ' BAD%0')  (' SMAD2%0'  ' MAP3K5%0')  (' SMAD2%0'  ' AKT1S1%0')  (' SMAD2%0'  ' SKI%0')  (' SMAD2%0'  ' SMAD3%0')  (' SMAD2%0'  ' MAPKAPK2%0')  (' SMAD2%0'  ' DUSP1_g%0')  (' SMAD2%0'  ' MSK_f%0')  (' SMAD2%0'  ' GRAP2%0')  (' SMAD2%0'  ' TAB_f%0')  (' SMAD2%0'  ' ATF2%0')  (' SMAD2%0'  ' SMAD5%0')  (' SMAD2%0'  ' SMAD1%0')  (' SMAD2%0'  ' FOS%0')  (' SMAD2%0'  ' JUN%0')  (' SMAD2%0'  ' MAP3K7%0')  (' SMAD2%0'  ' NLK%0')  (' SMAD2%0'  ' SMAD7_g%0')  (' SMAD2%0'  ' SMAD6_g%0')  (' SMAD2%0'  ' AP1_c%0')  (' SMAD2%0'  ' ACVR1%0')  (' SMAD2%0'  ' PTPN6%0')  (' SMAD2%0'  ' CDC42%0')  (' SMAD2%0'  ' GRB2%0')  (' SMAD2%0'  ' TGFBR1%0')  (' SMAD2%0'  ' SMURF1%0')  (' SMAD2%0'  ' SMURF2%0')  (' SMAD2%0'  ' RHOA%0')  (' SMAD2%0'  ' BMPR2%0')  (' SMAD2%0'  ' PARD6A%0')  (' SMAD2%0'  ' DAAM1%0')  (' SMAD2%0'  ' SFRP1_g%0')  (' SMAD2%0'  ' PPM1A%0')  (' SMAD2%0'  ' CFL_f%0')  (' SMAD2%0'  ' PAK1%0')  (' SMAD2%0'  ' MAP3K11%0')  (' SMAD2%0'  ' MAP3K4%0')  (' SMAD2%0'  ' LIMK1%0')  (' SMAD2%0'  ' ROCK1%0')  (' SMAD2%0'  ' ITCH%0')  (' SMAD2%0'  ' ARHGAP24%0')  (' SMAD2%0'  ' TIAM1%0')  (' SMAD2%0'  ' RND3%0')  (' SMAD2%0'  ' MAPK8IP3%0')  (' SMAD2%0'  ' MXD1%0')  (' SMAD2%0'  ' PIP3%0')  (' MDM2_g%0'  ' SRC%0')  (' MDM2_g%0'  ' CSK%0')  (' MDM2_g%0'  ' CHUK%0')  (' MDM2_g%0'  ' RAC_f%0')  (' MDM2_g%0'  ' DUSP1%0')  (' MDM2_g%0'  ' TGFBR2%0')  (' MDM2_g%0'  ' ILR_f%0')  (' MDM2_g%0'  ' SYK%0')  (' MDM2_g%0'  ' IRAK1%0')  (' MDM2_g%0'  ' SHC1%0')  (' MDM2_g%0'  ' JAK_f%0')  (' MDM2_g%0'  ' CBPp300_c%0')  (' MDM2_g%0'  ' SKP2%0')  (' MDM2_g%0'  ' TP53%0')  (' MDM2_g%0'  ' SMAD7%0')  (' MDM2_g%0'  ' SMAD6%0')  (' MDM2_g%0'  ' DKK_f%0')  (' MDM2_g%0'  ' FOXO_f%0')  (' MDM2_g%0'  ' TCF7_f%0')  (' MDM2_g%0'  ' DKK_g%0')  (' MDM2_g%0'  ' MYC%0')  (' MDM2_g%0'  ' CCND1%0')  (' MDM2_g%0'  ' EGR1%0')  (' MDM2_g%0'  ' MMP_f%0')  (' MDM2_g%0'  ' PTEN_g%0')  (' MDM2_g%0'  ' RTPK_f%0')  (' MDM2_g%0'  ' CTNNB1%0')  (' MDM2_g%0'  'LEF1%0')  (' MDM2_g%0'  'SFRP1%0')  (' MDM2_g%0'  'FZD_f%0')  (' MDM2_g%0'  ' CASP8%0')  (' MDM2_g%0'  ' REL_f%0')  (' MDM2_g%0'  ' NFKB_f%0')  (' MDM2_g%0'  ' DVL_f%0')  (' MDM2_g%0'  ' LRP_f%0')  (' MDM2_g%0'  ' BTRC%0')  (' MDM2_g%0'  ' CK1_f%0')  (' MDM2_g%0'  ' AXIN1%0')  (' MDM2_g%0'  ' mTORC2_c%0')  (' MDM2_g%0'  ' PDPK1%0')  (' MDM2_g%0'  ' MEK_f%0')  (' MDM2_g%0'  ' CYCS%0')  (' MDM2_g%0'  ' CASP9%0')  (' MDM2_g%0'  ' GSK3_f%0')  (' MDM2_g%0'  ' IRS1%0')  (' MDM2_g%0'  ' MDM2%0')  (' MDM2_g%0'  ' AKT_f%0')  (' MDM2_g%0'  ' BCL2%0')  (' MDM2_g%0'  ' RAF_f%0')  (' MDM2_g%0'  ' mTORC1_c%0')  (' MDM2_g%0'  ' RHEB%0')  (' MDM2_g%0'  ' RTPK_g%0')  (' MDM2_g%0'  ' PTEN%0')  (' MDM2_g%0'  ' CASP3%0')  (' MDM2_g%0'  ' PIK3CA%0')  (' MDM2_g%0'  ' CREBBP%0')  (' MDM2_g%0'  ' PTPN11%0')  (' MDM2_g%0'  ' KRAS%0')  (' MDM2_g%0'  ' MAP2K4%0')  (' MDM2_g%0'  ' MAP2K7%0')  (' MDM2_g%0'  ' MAPK14%0')  (' MDM2_g%0'  ' JNK_f%0')  (' MDM2_g%0'  ' MAP2K3%0')  (' MDM2_g%0'  ' ERK_f%0')  (' MDM2_g%0'  ' LIF%0')  (' MDM2_g%0'  ' PPP1CA%0')  (' MDM2_g%0'  ' GAB_f%0')  (' MDM2_g%0'  ' SOS1%0')  (' MDM2_g%0'  ' PRKCA%0')  (' MDM2_g%0'  ' VAV1%0')  (' MDM2_g%0'  ' PLCG1%0')  (' MDM2_g%0'  ' PRKCD%0')  (' MDM2_g%0'  ' RSK_f%0')  (' MDM2_g%0'  ' S6K_f%0')  (' MDM2_g%0'  ' PLK1%0')  (' MDM2_g%0'  ' ILK%0')  (' MDM2_g%0'  ' SOCS1%0')  (' MDM2_g%0'  ' DUSP6%0')  (' MDM2_g%0'  ' STAT3%0')  (' MDM2_g%0'  ' LIMK2%0')  (' MDM2_g%0'  ' EP300%0')  (' MDM2_g%0'  ' STAT1%0')  (' MDM2_g%0'  ' IKBKB%0')  (' MDM2_g%0'  ' SRF%0')  (' MDM2_g%0'  ' PIAS1%0')  (' MDM2_g%0'  ' TRAF6%0')  (' MDM2_g%0'  ' SOCS1_g%0')  (' MDM2_g%0'  ' ISGF3_c%0')  (' MDM2_g%0'  ' STAT2%0')  (' MDM2_g%0'  ' CFLAR%0')  (' MDM2_g%0'  ' SMAD2%0')  (' MDM2_g%0'  ' BAX%0')  (' MDM2_g%0'  ' PRKACA%0')  (' MDM2_g%0'  ' TGFB1%0')  (' MDM2_g%0'  ' MAP3K8%0')  (' MDM2_g%0'  ' TSC_f%0')  (' MDM2_g%0'  ' SMAD4%0')  (' MDM2_g%0'  ' BAD%0')  (' MDM2_g%0'  ' MAP3K5%0')  (' MDM2_g%0'  ' AKT1S1%0')  (' MDM2_g%0'  ' SKI%0')  (' MDM2_g%0'  ' SMAD3%0')  (' MDM2_g%0'  ' MAPKAPK2%0')  (' MDM2_g%0'  ' DUSP1_g%0')  (' MDM2_g%0'  ' MSK_f%0')  (' MDM2_g%0'  ' GRAP2%0')  (' MDM2_g%0'  ' TAB_f%0')  (' MDM2_g%0'  ' ATF2%0')  (' MDM2_g%0'  ' SMAD5%0')  (' MDM2_g%0'  ' SMAD1%0')  (' MDM2_g%0'  ' FOS%0')  (' MDM2_g%0'  ' JUN%0')  (' MDM2_g%0'  ' MAP3K7%0')  (' MDM2_g%0'  ' NLK%0')  (' MDM2_g%0'  ' SMAD7_g%0')  (' MDM2_g%0'  ' SMAD6_g%0')  (' MDM2_g%0'  ' AP1_c%0')  (' MDM2_g%0'  ' ACVR1%0')  (' MDM2_g%0'  ' PTPN6%0')  (' MDM2_g%0'  ' CDC42%0')  (' MDM2_g%0'  ' GRB2%0')  (' MDM2_g%0'  ' TGFBR1%0')  (' MDM2_g%0'  ' SMURF1%0')  (' MDM2_g%0'  ' SMURF2%0')  (' MDM2_g%0'  ' RHOA%0')  (' MDM2_g%0'  ' BMPR2%0')  (' MDM2_g%0'  ' PARD6A%0')  (' MDM2_g%0'  ' DAAM1%0')  (' MDM2_g%0'  ' SFRP1_g%0')  (' MDM2_g%0'  ' PPM1A%0')  (' MDM2_g%0'  ' CFL_f%0')  (' MDM2_g%0'  ' PAK1%0')  (' MDM2_g%0'  ' MAP3K11%0')  (' MDM2_g%0'  ' MAP3K4%0')  (' MDM2_g%0'  ' LIMK1%0')  (' MDM2_g%0'  ' ROCK1%0')  (' MDM2_g%0'  ' ITCH%0')  (' MDM2_g%0'  ' ARHGAP24%0')  (' MDM2_g%0'  ' TIAM1%0')  (' MDM2_g%0'  ' RND3%0')  (' MDM2_g%0'  ' MAPK8IP3%0')  (' MDM2_g%0'  ' MXD1%0')  (' MDM2_g%0'  ' PIP3%0')  (' BAX%0'  ' SRC%0')  (' BAX%0'  ' CSK%0')  (' BAX%0'  ' CHUK%0')  (' BAX%0'  ' RAC_f%0')  (' BAX%0'  ' DUSP1%0')  (' BAX%0'  ' TGFBR2%0')  (' BAX%0'  ' ILR_f%0')  (' BAX%0'  ' SYK%0')  (' BAX%0'  ' IRAK1%0')  (' BAX%0'  ' SHC1%0')  (' BAX%0'  ' JAK_f%0')  (' BAX%0'  ' CBPp300_c%0')  (' BAX%0'  ' SKP2%0')  (' BAX%0'  ' TP53%0')  (' BAX%0'  ' SMAD7%0')  (' BAX%0'  ' SMAD6%0')  (' BAX%0'  ' DKK_f%0')  (' BAX%0'  ' FOXO_f%0')  (' BAX%0'  ' TCF7_f%0')  (' BAX%0'  ' DKK_g%0')  (' BAX%0'  ' MYC%0')  (' BAX%0'  ' CCND1%0')  (' BAX%0'  ' EGR1%0')  (' BAX%0'  ' MMP_f%0')  (' BAX%0'  ' PTEN_g%0')  (' BAX%0'  ' RTPK_f%0')  (' BAX%0'  ' CTNNB1%0')  (' BAX%0'  'LEF1%0')  (' BAX%0'  'SFRP1%0')  (' BAX%0'  'FZD_f%0')  (' BAX%0'  ' CASP8%0')  (' BAX%0'  ' REL_f%0')  (' BAX%0'  ' NFKB_f%0')  (' BAX%0'  ' DVL_f%0')  (' BAX%0'  ' LRP_f%0')  (' BAX%0'  ' BTRC%0')  (' BAX%0'  ' CK1_f%0')  (' BAX%0'  ' AXIN1%0')  (' BAX%0'  ' mTORC2_c%0')  (' BAX%0'  ' PDPK1%0')  (' BAX%0'  ' MEK_f%0')  (' BAX%0'  ' CYCS%0')  (' BAX%0'  ' CASP9%0')  (' BAX%0'  ' GSK3_f%0')  (' BAX%0'  ' IRS1%0')  (' BAX%0'  ' MDM2%0')  (' BAX%0'  ' AKT_f%0')  (' BAX%0'  ' BCL2%0')  (' BAX%0'  ' RAF_f%0')  (' BAX%0'  ' mTORC1_c%0')  (' BAX%0'  ' RHEB%0')  (' BAX%0'  ' RTPK_g%0')  (' BAX%0'  ' PTEN%0')  (' BAX%0'  ' CASP3%0')  (' BAX%0'  ' PIK3CA%0')  (' BAX%0'  ' CREBBP%0')  (' BAX%0'  ' PTPN11%0')  (' BAX%0'  ' KRAS%0')  (' BAX%0'  ' MAP2K4%0')  (' BAX%0'  ' MAP2K7%0')  (' BAX%0'  ' MAPK14%0')  (' BAX%0'  ' JNK_f%0')  (' BAX%0'  ' MAP2K3%0')  (' BAX%0'  ' ERK_f%0')  (' BAX%0'  ' LIF%0')  (' BAX%0'  ' PPP1CA%0')  (' BAX%0'  ' GAB_f%0')  (' BAX%0'  ' SOS1%0')  (' BAX%0'  ' PRKCA%0')  (' BAX%0'  ' VAV1%0')  (' BAX%0'  ' PLCG1%0')  (' BAX%0'  ' PRKCD%0')  (' BAX%0'  ' RSK_f%0')  (' BAX%0'  ' S6K_f%0')  (' BAX%0'  ' PLK1%0')  (' BAX%0'  ' ILK%0')  (' BAX%0'  ' SOCS1%0')  (' BAX%0'  ' DUSP6%0')  (' BAX%0'  ' STAT3%0')  (' BAX%0'  ' LIMK2%0')  (' BAX%0'  ' EP300%0')  (' BAX%0'  ' STAT1%0')  (' BAX%0'  ' IKBKB%0')  (' BAX%0'  ' SRF%0')  (' BAX%0'  ' PIAS1%0')  (' BAX%0'  ' TRAF6%0')  (' BAX%0'  ' SOCS1_g%0')  (' BAX%0'  ' ISGF3_c%0')  (' BAX%0'  ' STAT2%0')  (' BAX%0'  ' CFLAR%0')  (' BAX%0'  ' SMAD2%0')  (' BAX%0'  ' MDM2_g%0')  (' BAX%0'  ' PRKACA%0')  (' BAX%0'  ' TGFB1%0')  (' BAX%0'  ' MAP3K8%0')  (' BAX%0'  ' TSC_f%0')  (' BAX%0'  ' SMAD4%0')  (' BAX%0'  ' BAD%0')  (' BAX%0'  ' MAP3K5%0')  (' BAX%0'  ' AKT1S1%0')  (' BAX%0'  ' SKI%0')  (' BAX%0'  ' SMAD3%0')  (' BAX%0'  ' MAPKAPK2%0')  (' BAX%0'  ' DUSP1_g%0')  (' BAX%0'  ' MSK_f%0')  (' BAX%0'  ' GRAP2%0')  (' BAX%0'  ' TAB_f%0')  (' BAX%0'  ' ATF2%0')  (' BAX%0'  ' SMAD5%0')  (' BAX%0'  ' SMAD1%0')  (' BAX%0'  ' FOS%0')  (' BAX%0'  ' JUN%0')  (' BAX%0'  ' MAP3K7%0')  (' BAX%0'  ' NLK%0')  (' BAX%0'  ' SMAD7_g%0')  (' BAX%0'  ' SMAD6_g%0')  (' BAX%0'  ' AP1_c%0')  (' BAX%0'  ' ACVR1%0')  (' BAX%0'  ' PTPN6%0')  (' BAX%0'  ' CDC42%0')  (' BAX%0'  ' GRB2%0')  (' BAX%0'  ' TGFBR1%0')  (' BAX%0'  ' SMURF1%0')  (' BAX%0'  ' SMURF2%0')  (' BAX%0'  ' RHOA%0')  (' BAX%0'  ' BMPR2%0')  (' BAX%0'  ' PARD6A%0')  (' BAX%0'  ' DAAM1%0')  (' BAX%0'  ' SFRP1_g%0')  (' BAX%0'  ' PPM1A%0')  (' BAX%0'  ' CFL_f%0')  (' BAX%0'  ' PAK1%0')  (' BAX%0'  ' MAP3K11%0')  (' BAX%0'  ' MAP3K4%0')  (' BAX%0'  ' LIMK1%0')  (' BAX%0'  ' ROCK1%0')  (' BAX%0'  ' ITCH%0')  (' BAX%0'  ' ARHGAP24%0')  (' BAX%0'  ' TIAM1%0')  (' BAX%0'  ' RND3%0')  (' BAX%0'  ' MAPK8IP3%0')  (' BAX%0'  ' MXD1%0')  (' BAX%0'  ' PIP3%0')  (' PRKACA%0'  ' SRC%0')  (' PRKACA%0'  ' CSK%0')  (' PRKACA%0'  ' CHUK%0')  (' PRKACA%0'  ' RAC_f%0')  (' PRKACA%0'  ' DUSP1%0')  (' PRKACA%0'  ' TGFBR2%0')  (' PRKACA%0'  ' ILR_f%0')  (' PRKACA%0'  ' SYK%0')  (' PRKACA%0'  ' IRAK1%0')  (' PRKACA%0'  ' SHC1%0')  (' PRKACA%0'  ' JAK_f%0')  (' PRKACA%0'  ' CBPp300_c%0')  (' PRKACA%0'  ' SKP2%0')  (' PRKACA%0'  ' TP53%0')  (' PRKACA%0'  ' SMAD7%0')  (' PRKACA%0'  ' SMAD6%0')  (' PRKACA%0'  ' DKK_f%0')  (' PRKACA%0'  ' FOXO_f%0')  (' PRKACA%0'  ' TCF7_f%0')  (' PRKACA%0'  ' DKK_g%0')  (' PRKACA%0'  ' MYC%0')  (' PRKACA%0'  ' CCND1%0')  (' PRKACA%0'  ' EGR1%0')  (' PRKACA%0'  ' MMP_f%0')  (' PRKACA%0'  ' PTEN_g%0')  (' PRKACA%0'  ' RTPK_f%0')  (' PRKACA%0'  ' CTNNB1%0')  (' PRKACA%0'  'LEF1%0')  (' PRKACA%0'  'SFRP1%0')  (' PRKACA%0'  'FZD_f%0')  (' PRKACA%0'  ' CASP8%0')  (' PRKACA%0'  ' REL_f%0')  (' PRKACA%0'  ' NFKB_f%0')  (' PRKACA%0'  ' DVL_f%0')  (' PRKACA%0'  ' LRP_f%0')  (' PRKACA%0'  ' BTRC%0')  (' PRKACA%0'  ' CK1_f%0')  (' PRKACA%0'  ' AXIN1%0')  (' PRKACA%0'  ' mTORC2_c%0')  (' PRKACA%0'  ' PDPK1%0')  (' PRKACA%0'  ' MEK_f%0')  (' PRKACA%0'  ' CYCS%0')  (' PRKACA%0'  ' CASP9%0')  (' PRKACA%0'  ' GSK3_f%0')  (' PRKACA%0'  ' IRS1%0')  (' PRKACA%0'  ' MDM2%0')  (' PRKACA%0'  ' AKT_f%0')  (' PRKACA%0'  ' BCL2%0')  (' PRKACA%0'  ' RAF_f%0')  (' PRKACA%0'  ' mTORC1_c%0')  (' PRKACA%0'  ' RHEB%0')  (' PRKACA%0'  ' RTPK_g%0')  (' PRKACA%0'  ' PTEN%0')  (' PRKACA%0'  ' CASP3%0')  (' PRKACA%0'  ' PIK3CA%0')  (' PRKACA%0'  ' CREBBP%0')  (' PRKACA%0'  ' PTPN11%0')  (' PRKACA%0'  ' KRAS%0')  (' PRKACA%0'  ' MAP2K4%0')  (' PRKACA%0'  ' MAP2K7%0')  (' PRKACA%0'  ' MAPK14%0')  (' PRKACA%0'  ' JNK_f%0')  (' PRKACA%0'  ' MAP2K3%0')  (' PRKACA%0'  ' ERK_f%0')  (' PRKACA%0'  ' LIF%0')  (' PRKACA%0'  ' PPP1CA%0')  (' PRKACA%0'  ' GAB_f%0')  (' PRKACA%0'  ' SOS1%0')  (' PRKACA%0'  ' PRKCA%0')  (' PRKACA%0'  ' VAV1%0')  (' PRKACA%0'  ' PLCG1%0')  (' PRKACA%0'  ' PRKCD%0')  (' PRKACA%0'  ' RSK_f%0')  (' PRKACA%0'  ' S6K_f%0')  (' PRKACA%0'  ' PLK1%0')  (' PRKACA%0'  ' ILK%0')  (' PRKACA%0'  ' SOCS1%0')  (' PRKACA%0'  ' DUSP6%0')  (' PRKACA%0'  ' STAT3%0')  (' PRKACA%0'  ' LIMK2%0')  (' PRKACA%0'  ' EP300%0')  (' PRKACA%0'  ' STAT1%0')  (' PRKACA%0'  ' IKBKB%0')  (' PRKACA%0'  ' SRF%0')  (' PRKACA%0'  ' PIAS1%0')  (' PRKACA%0'  ' TRAF6%0')  (' PRKACA%0'  ' SOCS1_g%0')  (' PRKACA%0'  ' ISGF3_c%0')  (' PRKACA%0'  ' STAT2%0')  (' PRKACA%0'  ' CFLAR%0')  (' PRKACA%0'  ' SMAD2%0')  (' PRKACA%0'  ' MDM2_g%0')  (' PRKACA%0'  ' BAX%0')  (' PRKACA%0'  ' TGFB1%0')  (' PRKACA%0'  ' MAP3K8%0')  (' PRKACA%0'  ' TSC_f%0')  (' PRKACA%0'  ' SMAD4%0')  (' PRKACA%0'  ' BAD%0')  (' PRKACA%0'  ' MAP3K5%0')  (' PRKACA%0'  ' AKT1S1%0')  (' PRKACA%0'  ' SKI%0')  (' PRKACA%0'  ' SMAD3%0')  (' PRKACA%0'  ' MAPKAPK2%0')  (' PRKACA%0'  ' DUSP1_g%0')  (' PRKACA%0'  ' MSK_f%0')  (' PRKACA%0'  ' GRAP2%0')  (' PRKACA%0'  ' TAB_f%0')  (' PRKACA%0'  ' ATF2%0')  (' PRKACA%0'  ' SMAD5%0')  (' PRKACA%0'  ' SMAD1%0')  (' PRKACA%0'  ' FOS%0')  (' PRKACA%0'  ' JUN%0')  (' PRKACA%0'  ' MAP3K7%0')  (' PRKACA%0'  ' NLK%0')  (' PRKACA%0'  ' SMAD7_g%0')  (' PRKACA%0'  ' SMAD6_g%0')  (' PRKACA%0'  ' AP1_c%0')  (' PRKACA%0'  ' ACVR1%0')  (' PRKACA%0'  ' PTPN6%0')  (' PRKACA%0'  ' CDC42%0')  (' PRKACA%0'  ' GRB2%0')  (' PRKACA%0'  ' TGFBR1%0')  (' PRKACA%0'  ' SMURF1%0')  (' PRKACA%0'  ' SMURF2%0')  (' PRKACA%0'  ' RHOA%0')  (' PRKACA%0'  ' BMPR2%0')  (' PRKACA%0'  ' PARD6A%0')  (' PRKACA%0'  ' DAAM1%0')  (' PRKACA%0'  ' SFRP1_g%0')  (' PRKACA%0'  ' PPM1A%0')  (' PRKACA%0'  ' CFL_f%0')  (' PRKACA%0'  ' PAK1%0')  (' PRKACA%0'  ' MAP3K11%0')  (' PRKACA%0'  ' MAP3K4%0')  (' PRKACA%0'  ' LIMK1%0')  (' PRKACA%0'  ' ROCK1%0')  (' PRKACA%0'  ' ITCH%0')  (' PRKACA%0'  ' ARHGAP24%0')  (' PRKACA%0'  ' TIAM1%0')  (' PRKACA%0'  ' RND3%0')  (' PRKACA%0'  ' MAPK8IP3%0')  (' PRKACA%0'  ' MXD1%0')  (' PRKACA%0'  ' PIP3%0')  (' TGFB1%0'  ' SRC%0')  (' TGFB1%0'  ' CSK%0')  (' TGFB1%0'  ' CHUK%0')  (' TGFB1%0'  ' RAC_f%0')  (' TGFB1%0'  ' DUSP1%0')  (' TGFB1%0'  ' TGFBR2%0')  (' TGFB1%0'  ' ILR_f%0')  (' TGFB1%0'  ' SYK%0')  (' TGFB1%0'  ' IRAK1%0')  (' TGFB1%0'  ' SHC1%0')  (' TGFB1%0'  ' JAK_f%0')  (' TGFB1%0'  ' CBPp300_c%0')  (' TGFB1%0'  ' SKP2%0')  (' TGFB1%0'  ' TP53%0')  (' TGFB1%0'  ' SMAD7%0')  (' TGFB1%0'  ' SMAD6%0')  (' TGFB1%0'  ' DKK_f%0')  (' TGFB1%0'  ' FOXO_f%0')  (' TGFB1%0'  ' TCF7_f%0')  (' TGFB1%0'  ' DKK_g%0')  (' TGFB1%0'  ' MYC%0')  (' TGFB1%0'  ' CCND1%0')  (' TGFB1%0'  ' EGR1%0')  (' TGFB1%0'  ' MMP_f%0')  (' TGFB1%0'  ' PTEN_g%0')  (' TGFB1%0'  ' RTPK_f%0')  (' TGFB1%0'  ' CTNNB1%0')  (' TGFB1%0'  'LEF1%0')  (' TGFB1%0'  'SFRP1%0')  (' TGFB1%0'  'FZD_f%0')  (' TGFB1%0'  ' CASP8%0')  (' TGFB1%0'  ' REL_f%0')  (' TGFB1%0'  ' NFKB_f%0')  (' TGFB1%0'  ' DVL_f%0')  (' TGFB1%0'  ' LRP_f%0')  (' TGFB1%0'  ' BTRC%0')  (' TGFB1%0'  ' CK1_f%0')  (' TGFB1%0'  ' AXIN1%0')  (' TGFB1%0'  ' mTORC2_c%0')  (' TGFB1%0'  ' PDPK1%0')  (' TGFB1%0'  ' MEK_f%0')  (' TGFB1%0'  ' CYCS%0')  (' TGFB1%0'  ' CASP9%0')  (' TGFB1%0'  ' GSK3_f%0')  (' TGFB1%0'  ' IRS1%0')  (' TGFB1%0'  ' MDM2%0')  (' TGFB1%0'  ' AKT_f%0')  (' TGFB1%0'  ' BCL2%0')  (' TGFB1%0'  ' RAF_f%0')  (' TGFB1%0'  ' mTORC1_c%0')  (' TGFB1%0'  ' RHEB%0')  (' TGFB1%0'  ' RTPK_g%0')  (' TGFB1%0'  ' PTEN%0')  (' TGFB1%0'  ' CASP3%0')  (' TGFB1%0'  ' PIK3CA%0')  (' TGFB1%0'  ' CREBBP%0')  (' TGFB1%0'  ' PTPN11%0')  (' TGFB1%0'  ' KRAS%0')  (' TGFB1%0'  ' MAP2K4%0')  (' TGFB1%0'  ' MAP2K7%0')  (' TGFB1%0'  ' MAPK14%0')  (' TGFB1%0'  ' JNK_f%0')  (' TGFB1%0'  ' MAP2K3%0')  (' TGFB1%0'  ' ERK_f%0')  (' TGFB1%0'  ' LIF%0')  (' TGFB1%0'  ' PPP1CA%0')  (' TGFB1%0'  ' GAB_f%0')  (' TGFB1%0'  ' SOS1%0')  (' TGFB1%0'  ' PRKCA%0')  (' TGFB1%0'  ' VAV1%0')  (' TGFB1%0'  ' PLCG1%0')  (' TGFB1%0'  ' PRKCD%0')  (' TGFB1%0'  ' RSK_f%0')  (' TGFB1%0'  ' S6K_f%0')  (' TGFB1%0'  ' PLK1%0')  (' TGFB1%0'  ' ILK%0')  (' TGFB1%0'  ' SOCS1%0')  (' TGFB1%0'  ' DUSP6%0')  (' TGFB1%0'  ' STAT3%0')  (' TGFB1%0'  ' LIMK2%0')  (' TGFB1%0'  ' EP300%0')  (' TGFB1%0'  ' STAT1%0')  (' TGFB1%0'  ' IKBKB%0')  (' TGFB1%0'  ' SRF%0')  (' TGFB1%0'  ' PIAS1%0')  (' TGFB1%0'  ' TRAF6%0')  (' TGFB1%0'  ' SOCS1_g%0')  (' TGFB1%0'  ' ISGF3_c%0')  (' TGFB1%0'  ' STAT2%0')  (' TGFB1%0'  ' CFLAR%0')  (' TGFB1%0'  ' SMAD2%0')  (' TGFB1%0'  ' MDM2_g%0')  (' TGFB1%0'  ' BAX%0')  (' TGFB1%0'  ' PRKACA%0')  (' TGFB1%0'  ' MAP3K8%0')  (' TGFB1%0'  ' TSC_f%0')  (' TGFB1%0'  ' SMAD4%0')  (' TGFB1%0'  ' BAD%0')  (' TGFB1%0'  ' MAP3K5%0')  (' TGFB1%0'  ' AKT1S1%0')  (' TGFB1%0'  ' SKI%0')  (' TGFB1%0'  ' SMAD3%0')  (' TGFB1%0'  ' MAPKAPK2%0')  (' TGFB1%0'  ' DUSP1_g%0')  (' TGFB1%0'  ' MSK_f%0')  (' TGFB1%0'  ' GRAP2%0')  (' TGFB1%0'  ' TAB_f%0')  (' TGFB1%0'  ' ATF2%0')  (' TGFB1%0'  ' SMAD5%0')  (' TGFB1%0'  ' SMAD1%0')  (' TGFB1%0'  ' FOS%0')  (' TGFB1%0'  ' JUN%0')  (' TGFB1%0'  ' MAP3K7%0')  (' TGFB1%0'  ' NLK%0')  (' TGFB1%0'  ' SMAD7_g%0')  (' TGFB1%0'  ' SMAD6_g%0')  (' TGFB1%0'  ' AP1_c%0')  (' TGFB1%0'  ' ACVR1%0')  (' TGFB1%0'  ' PTPN6%0')  (' TGFB1%0'  ' CDC42%0')  (' TGFB1%0'  ' GRB2%0')  (' TGFB1%0'  ' TGFBR1%0')  (' TGFB1%0'  ' SMURF1%0')  (' TGFB1%0'  ' SMURF2%0')  (' TGFB1%0'  ' RHOA%0')  (' TGFB1%0'  ' BMPR2%0')  (' TGFB1%0'  ' PARD6A%0')  (' TGFB1%0'  ' DAAM1%0')  (' TGFB1%0'  ' SFRP1_g%0')  (' TGFB1%0'  ' PPM1A%0')  (' TGFB1%0'  ' CFL_f%0')  (' TGFB1%0'  ' PAK1%0')  (' TGFB1%0'  ' MAP3K11%0')  (' TGFB1%0'  ' MAP3K4%0')  (' TGFB1%0'  ' LIMK1%0')  (' TGFB1%0'  ' ROCK1%0')  (' TGFB1%0'  ' ITCH%0')  (' TGFB1%0'  ' ARHGAP24%0')  (' TGFB1%0'  ' TIAM1%0')  (' TGFB1%0'  ' RND3%0')  (' TGFB1%0'  ' MAPK8IP3%0')  (' TGFB1%0'  ' MXD1%0')  (' TGFB1%0'  ' PIP3%0')  (' MAP3K8%0'  ' SRC%0')  (' MAP3K8%0'  ' CSK%0')  (' MAP3K8%0'  ' CHUK%0')  (' MAP3K8%0'  ' RAC_f%0')  (' MAP3K8%0'  ' DUSP1%0')  (' MAP3K8%0'  ' TGFBR2%0')  (' MAP3K8%0'  ' ILR_f%0')  (' MAP3K8%0'  ' SYK%0')  (' MAP3K8%0'  ' IRAK1%0')  (' MAP3K8%0'  ' SHC1%0')  (' MAP3K8%0'  ' JAK_f%0')  (' MAP3K8%0'  ' CBPp300_c%0')  (' MAP3K8%0'  ' SKP2%0')  (' MAP3K8%0'  ' TP53%0')  (' MAP3K8%0'  ' SMAD7%0')  (' MAP3K8%0'  ' SMAD6%0')  (' MAP3K8%0'  ' DKK_f%0')  (' MAP3K8%0'  ' FOXO_f%0')  (' MAP3K8%0'  ' TCF7_f%0')  (' MAP3K8%0'  ' DKK_g%0')  (' MAP3K8%0'  ' MYC%0')  (' MAP3K8%0'  ' CCND1%0')  (' MAP3K8%0'  ' EGR1%0')  (' MAP3K8%0'  ' MMP_f%0')  (' MAP3K8%0'  ' PTEN_g%0')  (' MAP3K8%0'  ' RTPK_f%0')  (' MAP3K8%0'  ' CTNNB1%0')  (' MAP3K8%0'  'LEF1%0')  (' MAP3K8%0'  'SFRP1%0')  (' MAP3K8%0'  'FZD_f%0')  (' MAP3K8%0'  ' CASP8%0')  (' MAP3K8%0'  ' REL_f%0')  (' MAP3K8%0'  ' NFKB_f%0')  (' MAP3K8%0'  ' DVL_f%0')  (' MAP3K8%0'  ' LRP_f%0')  (' MAP3K8%0'  ' BTRC%0')  (' MAP3K8%0'  ' CK1_f%0')  (' MAP3K8%0'  ' AXIN1%0')  (' MAP3K8%0'  ' mTORC2_c%0')  (' MAP3K8%0'  ' PDPK1%0')  (' MAP3K8%0'  ' MEK_f%0')  (' MAP3K8%0'  ' CYCS%0')  (' MAP3K8%0'  ' CASP9%0')  (' MAP3K8%0'  ' GSK3_f%0')  (' MAP3K8%0'  ' IRS1%0')  (' MAP3K8%0'  ' MDM2%0')  (' MAP3K8%0'  ' AKT_f%0')  (' MAP3K8%0'  ' BCL2%0')  (' MAP3K8%0'  ' RAF_f%0')  (' MAP3K8%0'  ' mTORC1_c%0')  (' MAP3K8%0'  ' RHEB%0')  (' MAP3K8%0'  ' RTPK_g%0')  (' MAP3K8%0'  ' PTEN%0')  (' MAP3K8%0'  ' CASP3%0')  (' MAP3K8%0'  ' PIK3CA%0')  (' MAP3K8%0'  ' CREBBP%0')  (' MAP3K8%0'  ' PTPN11%0')  (' MAP3K8%0'  ' KRAS%0')  (' MAP3K8%0'  ' MAP2K4%0')  (' MAP3K8%0'  ' MAP2K7%0')  (' MAP3K8%0'  ' MAPK14%0')  (' MAP3K8%0'  ' JNK_f%0')  (' MAP3K8%0'  ' MAP2K3%0')  (' MAP3K8%0'  ' ERK_f%0')  (' MAP3K8%0'  ' LIF%0')  (' MAP3K8%0'  ' PPP1CA%0')  (' MAP3K8%0'  ' GAB_f%0')  (' MAP3K8%0'  ' SOS1%0')  (' MAP3K8%0'  ' PRKCA%0')  (' MAP3K8%0'  ' VAV1%0')  (' MAP3K8%0'  ' PLCG1%0')  (' MAP3K8%0'  ' PRKCD%0')  (' MAP3K8%0'  ' RSK_f%0')  (' MAP3K8%0'  ' S6K_f%0')  (' MAP3K8%0'  ' PLK1%0')  (' MAP3K8%0'  ' ILK%0')  (' MAP3K8%0'  ' SOCS1%0')  (' MAP3K8%0'  ' DUSP6%0')  (' MAP3K8%0'  ' STAT3%0')  (' MAP3K8%0'  ' LIMK2%0')  (' MAP3K8%0'  ' EP300%0')  (' MAP3K8%0'  ' STAT1%0')  (' MAP3K8%0'  ' IKBKB%0')  (' MAP3K8%0'  ' SRF%0')  (' MAP3K8%0'  ' PIAS1%0')  (' MAP3K8%0'  ' TRAF6%0')  (' MAP3K8%0'  ' SOCS1_g%0')  (' MAP3K8%0'  ' ISGF3_c%0')  (' MAP3K8%0'  ' STAT2%0')  (' MAP3K8%0'  ' CFLAR%0')  (' MAP3K8%0'  ' SMAD2%0')  (' MAP3K8%0'  ' MDM2_g%0')  (' MAP3K8%0'  ' BAX%0')  (' MAP3K8%0'  ' PRKACA%0')  (' MAP3K8%0'  ' TGFB1%0')  (' MAP3K8%0'  ' TSC_f%0')  (' MAP3K8%0'  ' SMAD4%0')  (' MAP3K8%0'  ' BAD%0')  (' MAP3K8%0'  ' MAP3K5%0')  (' MAP3K8%0'  ' AKT1S1%0')  (' MAP3K8%0'  ' SKI%0')  (' MAP3K8%0'  ' SMAD3%0')  (' MAP3K8%0'  ' MAPKAPK2%0')  (' MAP3K8%0'  ' DUSP1_g%0')  (' MAP3K8%0'  ' MSK_f%0')  (' MAP3K8%0'  ' GRAP2%0')  (' MAP3K8%0'  ' TAB_f%0')  (' MAP3K8%0'  ' ATF2%0')  (' MAP3K8%0'  ' SMAD5%0')  (' MAP3K8%0'  ' SMAD1%0')  (' MAP3K8%0'  ' FOS%0')  (' MAP3K8%0'  ' JUN%0')  (' MAP3K8%0'  ' MAP3K7%0')  (' MAP3K8%0'  ' NLK%0')  (' MAP3K8%0'  ' SMAD7_g%0')  (' MAP3K8%0'  ' SMAD6_g%0')  (' MAP3K8%0'  ' AP1_c%0')  (' MAP3K8%0'  ' ACVR1%0')  (' MAP3K8%0'  ' PTPN6%0')  (' MAP3K8%0'  ' CDC42%0')  (' MAP3K8%0'  ' GRB2%0')  (' MAP3K8%0'  ' TGFBR1%0')  (' MAP3K8%0'  ' SMURF1%0')  (' MAP3K8%0'  ' SMURF2%0')  (' MAP3K8%0'  ' RHOA%0')  (' MAP3K8%0'  ' BMPR2%0')  (' MAP3K8%0'  ' PARD6A%0')  (' MAP3K8%0'  ' DAAM1%0')  (' MAP3K8%0'  ' SFRP1_g%0')  (' MAP3K8%0'  ' PPM1A%0')  (' MAP3K8%0'  ' CFL_f%0')  (' MAP3K8%0'  ' PAK1%0')  (' MAP3K8%0'  ' MAP3K11%0')  (' MAP3K8%0'  ' MAP3K4%0')  (' MAP3K8%0'  ' LIMK1%0')  (' MAP3K8%0'  ' ROCK1%0')  (' MAP3K8%0'  ' ITCH%0')  (' MAP3K8%0'  ' ARHGAP24%0')  (' MAP3K8%0'  ' TIAM1%0')  (' MAP3K8%0'  ' RND3%0')  (' MAP3K8%0'  ' MAPK8IP3%0')  (' MAP3K8%0'  ' MXD1%0')  (' MAP3K8%0'  ' PIP3%0')  (' TSC_f%0'  ' SRC%0')  (' TSC_f%0'  ' CSK%0')  (' TSC_f%0'  ' CHUK%0')  (' TSC_f%0'  ' RAC_f%0')  (' TSC_f%0'  ' DUSP1%0')  (' TSC_f%0'  ' TGFBR2%0')  (' TSC_f%0'  ' ILR_f%0')  (' TSC_f%0'  ' SYK%0')  (' TSC_f%0'  ' IRAK1%0')  (' TSC_f%0'  ' SHC1%0')  (' TSC_f%0'  ' JAK_f%0')  (' TSC_f%0'  ' CBPp300_c%0')  (' TSC_f%0'  ' SKP2%0')  (' TSC_f%0'  ' TP53%0')  (' TSC_f%0'  ' SMAD7%0')  (' TSC_f%0'  ' SMAD6%0')  (' TSC_f%0'  ' DKK_f%0')  (' TSC_f%0'  ' FOXO_f%0')  (' TSC_f%0'  ' TCF7_f%0')  (' TSC_f%0'  ' DKK_g%0')  (' TSC_f%0'  ' MYC%0')  (' TSC_f%0'  ' CCND1%0')  (' TSC_f%0'  ' EGR1%0')  (' TSC_f%0'  ' MMP_f%0')  (' TSC_f%0'  ' PTEN_g%0')  (' TSC_f%0'  ' RTPK_f%0')  (' TSC_f%0'  ' CTNNB1%0')  (' TSC_f%0'  'LEF1%0')  (' TSC_f%0'  'SFRP1%0')  (' TSC_f%0'  'FZD_f%0')  (' TSC_f%0'  ' CASP8%0')  (' TSC_f%0'  ' REL_f%0')  (' TSC_f%0'  ' NFKB_f%0')  (' TSC_f%0'  ' DVL_f%0')  (' TSC_f%0'  ' LRP_f%0')  (' TSC_f%0'  ' BTRC%0')  (' TSC_f%0'  ' CK1_f%0')  (' TSC_f%0'  ' AXIN1%0')  (' TSC_f%0'  ' mTORC2_c%0')  (' TSC_f%0'  ' PDPK1%0')  (' TSC_f%0'  ' MEK_f%0')  (' TSC_f%0'  ' CYCS%0')  (' TSC_f%0'  ' CASP9%0')  (' TSC_f%0'  ' GSK3_f%0')  (' TSC_f%0'  ' IRS1%0')  (' TSC_f%0'  ' MDM2%0')  (' TSC_f%0'  ' AKT_f%0')  (' TSC_f%0'  ' BCL2%0')  (' TSC_f%0'  ' RAF_f%0')  (' TSC_f%0'  ' mTORC1_c%0')  (' TSC_f%0'  ' RHEB%0')  (' TSC_f%0'  ' RTPK_g%0')  (' TSC_f%0'  ' PTEN%0')  (' TSC_f%0'  ' CASP3%0')  (' TSC_f%0'  ' PIK3CA%0')  (' TSC_f%0'  ' CREBBP%0')  (' TSC_f%0'  ' PTPN11%0')  (' TSC_f%0'  ' KRAS%0')  (' TSC_f%0'  ' MAP2K4%0')  (' TSC_f%0'  ' MAP2K7%0')  (' TSC_f%0'  ' MAPK14%0')  (' TSC_f%0'  ' JNK_f%0')  (' TSC_f%0'  ' MAP2K3%0')  (' TSC_f%0'  ' ERK_f%0')  (' TSC_f%0'  ' LIF%0')  (' TSC_f%0'  ' PPP1CA%0')  (' TSC_f%0'  ' GAB_f%0')  (' TSC_f%0'  ' SOS1%0')  (' TSC_f%0'  ' PRKCA%0')  (' TSC_f%0'  ' VAV1%0')  (' TSC_f%0'  ' PLCG1%0')  (' TSC_f%0'  ' PRKCD%0')  (' TSC_f%0'  ' RSK_f%0')  (' TSC_f%0'  ' S6K_f%0')  (' TSC_f%0'  ' PLK1%0')  (' TSC_f%0'  ' ILK%0')  (' TSC_f%0'  ' SOCS1%0')  (' TSC_f%0'  ' DUSP6%0')  (' TSC_f%0'  ' STAT3%0')  (' TSC_f%0'  ' LIMK2%0')  (' TSC_f%0'  ' EP300%0')  (' TSC_f%0'  ' STAT1%0')  (' TSC_f%0'  ' IKBKB%0')  (' TSC_f%0'  ' SRF%0')  (' TSC_f%0'  ' PIAS1%0')  (' TSC_f%0'  ' TRAF6%0')  (' TSC_f%0'  ' SOCS1_g%0')  (' TSC_f%0'  ' ISGF3_c%0')  (' TSC_f%0'  ' STAT2%0')  (' TSC_f%0'  ' CFLAR%0')  (' TSC_f%0'  ' SMAD2%0')  (' TSC_f%0'  ' MDM2_g%0')  (' TSC_f%0'  ' BAX%0')  (' TSC_f%0'  ' PRKACA%0')  (' TSC_f%0'  ' TGFB1%0')  (' TSC_f%0'  ' MAP3K8%0')  (' TSC_f%0'  ' SMAD4%0')  (' TSC_f%0'  ' BAD%0')  (' TSC_f%0'  ' MAP3K5%0')  (' TSC_f%0'  ' AKT1S1%0')  (' TSC_f%0'  ' SKI%0')  (' TSC_f%0'  ' SMAD3%0')  (' TSC_f%0'  ' MAPKAPK2%0')  (' TSC_f%0'  ' DUSP1_g%0')  (' TSC_f%0'  ' MSK_f%0')  (' TSC_f%0'  ' GRAP2%0')  (' TSC_f%0'  ' TAB_f%0')  (' TSC_f%0'  ' ATF2%0')  (' TSC_f%0'  ' SMAD5%0')  (' TSC_f%0'  ' SMAD1%0')  (' TSC_f%0'  ' FOS%0')  (' TSC_f%0'  ' JUN%0')  (' TSC_f%0'  ' MAP3K7%0')  (' TSC_f%0'  ' NLK%0')  (' TSC_f%0'  ' SMAD7_g%0')  (' TSC_f%0'  ' SMAD6_g%0')  (' TSC_f%0'  ' AP1_c%0')  (' TSC_f%0'  ' ACVR1%0')  (' TSC_f%0'  ' PTPN6%0')  (' TSC_f%0'  ' CDC42%0')  (' TSC_f%0'  ' GRB2%0')  (' TSC_f%0'  ' TGFBR1%0')  (' TSC_f%0'  ' SMURF1%0')  (' TSC_f%0'  ' SMURF2%0')  (' TSC_f%0'  ' RHOA%0')  (' TSC_f%0'  ' BMPR2%0')  (' TSC_f%0'  ' PARD6A%0')  (' TSC_f%0'  ' DAAM1%0')  (' TSC_f%0'  ' SFRP1_g%0')  (' TSC_f%0'  ' PPM1A%0')  (' TSC_f%0'  ' CFL_f%0')  (' TSC_f%0'  ' PAK1%0')  (' TSC_f%0'  ' MAP3K11%0')  (' TSC_f%0'  ' MAP3K4%0')  (' TSC_f%0'  ' LIMK1%0')  (' TSC_f%0'  ' ROCK1%0')  (' TSC_f%0'  ' ITCH%0')  (' TSC_f%0'  ' ARHGAP24%0')  (' TSC_f%0'  ' TIAM1%0')  (' TSC_f%0'  ' RND3%0')  (' TSC_f%0'  ' MAPK8IP3%0')  (' TSC_f%0'  ' MXD1%0')  (' TSC_f%0'  ' PIP3%0')  (' SMAD4%0'  ' SRC%0')  (' SMAD4%0'  ' CSK%0')  (' SMAD4%0'  ' CHUK%0')  (' SMAD4%0'  ' RAC_f%0')  (' SMAD4%0'  ' DUSP1%0')  (' SMAD4%0'  ' TGFBR2%0')  (' SMAD4%0'  ' ILR_f%0')  (' SMAD4%0'  ' SYK%0')  (' SMAD4%0'  ' IRAK1%0')  (' SMAD4%0'  ' SHC1%0')  (' SMAD4%0'  ' JAK_f%0')  (' SMAD4%0'  ' CBPp300_c%0')  (' SMAD4%0'  ' SKP2%0')  (' SMAD4%0'  ' TP53%0')  (' SMAD4%0'  ' SMAD7%0')  (' SMAD4%0'  ' SMAD6%0')  (' SMAD4%0'  ' DKK_f%0')  (' SMAD4%0'  ' FOXO_f%0')  (' SMAD4%0'  ' TCF7_f%0')  (' SMAD4%0'  ' DKK_g%0')  (' SMAD4%0'  ' MYC%0')  (' SMAD4%0'  ' CCND1%0')  (' SMAD4%0'  ' EGR1%0')  (' SMAD4%0'  ' MMP_f%0')  (' SMAD4%0'  ' PTEN_g%0')  (' SMAD4%0'  ' RTPK_f%0')  (' SMAD4%0'  ' CTNNB1%0')  (' SMAD4%0'  'LEF1%0')  (' SMAD4%0'  'SFRP1%0')  (' SMAD4%0'  'FZD_f%0')  (' SMAD4%0'  ' CASP8%0')  (' SMAD4%0'  ' REL_f%0')  (' SMAD4%0'  ' NFKB_f%0')  (' SMAD4%0'  ' DVL_f%0')  (' SMAD4%0'  ' LRP_f%0')  (' SMAD4%0'  ' BTRC%0')  (' SMAD4%0'  ' CK1_f%0')  (' SMAD4%0'  ' AXIN1%0')  (' SMAD4%0'  ' mTORC2_c%0')  (' SMAD4%0'  ' PDPK1%0')  (' SMAD4%0'  ' MEK_f%0')  (' SMAD4%0'  ' CYCS%0')  (' SMAD4%0'  ' CASP9%0')  (' SMAD4%0'  ' GSK3_f%0')  (' SMAD4%0'  ' IRS1%0')  (' SMAD4%0'  ' MDM2%0')  (' SMAD4%0'  ' AKT_f%0')  (' SMAD4%0'  ' BCL2%0')  (' SMAD4%0'  ' RAF_f%0')  (' SMAD4%0'  ' mTORC1_c%0')  (' SMAD4%0'  ' RHEB%0')  (' SMAD4%0'  ' RTPK_g%0')  (' SMAD4%0'  ' PTEN%0')  (' SMAD4%0'  ' CASP3%0')  (' SMAD4%0'  ' PIK3CA%0')  (' SMAD4%0'  ' CREBBP%0')  (' SMAD4%0'  ' PTPN11%0')  (' SMAD4%0'  ' KRAS%0')  (' SMAD4%0'  ' MAP2K4%0')  (' SMAD4%0'  ' MAP2K7%0')  (' SMAD4%0'  ' MAPK14%0')  (' SMAD4%0'  ' JNK_f%0')  (' SMAD4%0'  ' MAP2K3%0')  (' SMAD4%0'  ' ERK_f%0')  (' SMAD4%0'  ' LIF%0')  (' SMAD4%0'  ' PPP1CA%0')  (' SMAD4%0'  ' GAB_f%0')  (' SMAD4%0'  ' SOS1%0')  (' SMAD4%0'  ' PRKCA%0')  (' SMAD4%0'  ' VAV1%0')  (' SMAD4%0'  ' PLCG1%0')  (' SMAD4%0'  ' PRKCD%0')  (' SMAD4%0'  ' RSK_f%0')  (' SMAD4%0'  ' S6K_f%0')  (' SMAD4%0'  ' PLK1%0')  (' SMAD4%0'  ' ILK%0')  (' SMAD4%0'  ' SOCS1%0')  (' SMAD4%0'  ' DUSP6%0')  (' SMAD4%0'  ' STAT3%0')  (' SMAD4%0'  ' LIMK2%0')  (' SMAD4%0'  ' EP300%0')  (' SMAD4%0'  ' STAT1%0')  (' SMAD4%0'  ' IKBKB%0')  (' SMAD4%0'  ' SRF%0')  (' SMAD4%0'  ' PIAS1%0')  (' SMAD4%0'  ' TRAF6%0')  (' SMAD4%0'  ' SOCS1_g%0')  (' SMAD4%0'  ' ISGF3_c%0')  (' SMAD4%0'  ' STAT2%0')  (' SMAD4%0'  ' CFLAR%0')  (' SMAD4%0'  ' SMAD2%0')  (' SMAD4%0'  ' MDM2_g%0')  (' SMAD4%0'  ' BAX%0')  (' SMAD4%0'  ' PRKACA%0')  (' SMAD4%0'  ' TGFB1%0')  (' SMAD4%0'  ' MAP3K8%0')  (' SMAD4%0'  ' TSC_f%0')  (' SMAD4%0'  ' BAD%0')  (' SMAD4%0'  ' MAP3K5%0')  (' SMAD4%0'  ' AKT1S1%0')  (' SMAD4%0'  ' SKI%0')  (' SMAD4%0'  ' SMAD3%0')  (' SMAD4%0'  ' MAPKAPK2%0')  (' SMAD4%0'  ' DUSP1_g%0')  (' SMAD4%0'  ' MSK_f%0')  (' SMAD4%0'  ' GRAP2%0')  (' SMAD4%0'  ' TAB_f%0')  (' SMAD4%0'  ' ATF2%0')  (' SMAD4%0'  ' SMAD5%0')  (' SMAD4%0'  ' SMAD1%0')  (' SMAD4%0'  ' FOS%0')  (' SMAD4%0'  ' JUN%0')  (' SMAD4%0'  ' MAP3K7%0')  (' SMAD4%0'  ' NLK%0')  (' SMAD4%0'  ' SMAD7_g%0')  (' SMAD4%0'  ' SMAD6_g%0')  (' SMAD4%0'  ' AP1_c%0')  (' SMAD4%0'  ' ACVR1%0')  (' SMAD4%0'  ' PTPN6%0')  (' SMAD4%0'  ' CDC42%0')  (' SMAD4%0'  ' GRB2%0')  (' SMAD4%0'  ' TGFBR1%0')  (' SMAD4%0'  ' SMURF1%0')  (' SMAD4%0'  ' SMURF2%0')  (' SMAD4%0'  ' RHOA%0')  (' SMAD4%0'  ' BMPR2%0')  (' SMAD4%0'  ' PARD6A%0')  (' SMAD4%0'  ' DAAM1%0')  (' SMAD4%0'  ' SFRP1_g%0')  (' SMAD4%0'  ' PPM1A%0')  (' SMAD4%0'  ' CFL_f%0')  (' SMAD4%0'  ' PAK1%0')  (' SMAD4%0'  ' MAP3K11%0')  (' SMAD4%0'  ' MAP3K4%0')  (' SMAD4%0'  ' LIMK1%0')  (' SMAD4%0'  ' ROCK1%0')  (' SMAD4%0'  ' ITCH%0')  (' SMAD4%0'  ' ARHGAP24%0')  (' SMAD4%0'  ' TIAM1%0')  (' SMAD4%0'  ' RND3%0')  (' SMAD4%0'  ' MAPK8IP3%0')  (' SMAD4%0'  ' MXD1%0')  (' SMAD4%0'  ' PIP3%0')  (' BAD%0'  ' SRC%0')  (' BAD%0'  ' CSK%0')  (' BAD%0'  ' CHUK%0')  (' BAD%0'  ' RAC_f%0')  (' BAD%0'  ' DUSP1%0')  (' BAD%0'  ' TGFBR2%0')  (' BAD%0'  ' ILR_f%0')  (' BAD%0'  ' SYK%0')  (' BAD%0'  ' IRAK1%0')  (' BAD%0'  ' SHC1%0')  (' BAD%0'  ' JAK_f%0')  (' BAD%0'  ' CBPp300_c%0')  (' BAD%0'  ' SKP2%0')  (' BAD%0'  ' TP53%0')  (' BAD%0'  ' SMAD7%0')  (' BAD%0'  ' SMAD6%0')  (' BAD%0'  ' DKK_f%0')  (' BAD%0'  ' FOXO_f%0')  (' BAD%0'  ' TCF7_f%0')  (' BAD%0'  ' DKK_g%0')  (' BAD%0'  ' MYC%0')  (' BAD%0'  ' CCND1%0')  (' BAD%0'  ' EGR1%0')  (' BAD%0'  ' MMP_f%0')  (' BAD%0'  ' PTEN_g%0')  (' BAD%0'  ' RTPK_f%0')  (' BAD%0'  ' CTNNB1%0')  (' BAD%0'  'LEF1%0')  (' BAD%0'  'SFRP1%0')  (' BAD%0'  'FZD_f%0')  (' BAD%0'  ' CASP8%0')  (' BAD%0'  ' REL_f%0')  (' BAD%0'  ' NFKB_f%0')  (' BAD%0'  ' DVL_f%0')  (' BAD%0'  ' LRP_f%0')  (' BAD%0'  ' BTRC%0')  (' BAD%0'  ' CK1_f%0')  (' BAD%0'  ' AXIN1%0')  (' BAD%0'  ' mTORC2_c%0')  (' BAD%0'  ' PDPK1%0')  (' BAD%0'  ' MEK_f%0')  (' BAD%0'  ' CYCS%0')  (' BAD%0'  ' CASP9%0')  (' BAD%0'  ' GSK3_f%0')  (' BAD%0'  ' IRS1%0')  (' BAD%0'  ' MDM2%0')  (' BAD%0'  ' AKT_f%0')  (' BAD%0'  ' BCL2%0')  (' BAD%0'  ' RAF_f%0')  (' BAD%0'  ' mTORC1_c%0')  (' BAD%0'  ' RHEB%0')  (' BAD%0'  ' RTPK_g%0')  (' BAD%0'  ' PTEN%0')  (' BAD%0'  ' CASP3%0')  (' BAD%0'  ' PIK3CA%0')  (' BAD%0'  ' CREBBP%0')  (' BAD%0'  ' PTPN11%0')  (' BAD%0'  ' KRAS%0')  (' BAD%0'  ' MAP2K4%0')  (' BAD%0'  ' MAP2K7%0')  (' BAD%0'  ' MAPK14%0')  (' BAD%0'  ' JNK_f%0')  (' BAD%0'  ' MAP2K3%0')  (' BAD%0'  ' ERK_f%0')  (' BAD%0'  ' LIF%0')  (' BAD%0'  ' PPP1CA%0')  (' BAD%0'  ' GAB_f%0')  (' BAD%0'  ' SOS1%0')  (' BAD%0'  ' PRKCA%0')  (' BAD%0'  ' VAV1%0')  (' BAD%0'  ' PLCG1%0')  (' BAD%0'  ' PRKCD%0')  (' BAD%0'  ' RSK_f%0')  (' BAD%0'  ' S6K_f%0')  (' BAD%0'  ' PLK1%0')  (' BAD%0'  ' ILK%0')  (' BAD%0'  ' SOCS1%0')  (' BAD%0'  ' DUSP6%0')  (' BAD%0'  ' STAT3%0')  (' BAD%0'  ' LIMK2%0')  (' BAD%0'  ' EP300%0')  (' BAD%0'  ' STAT1%0')  (' BAD%0'  ' IKBKB%0')  (' BAD%0'  ' SRF%0')  (' BAD%0'  ' PIAS1%0')  (' BAD%0'  ' TRAF6%0')  (' BAD%0'  ' SOCS1_g%0')  (' BAD%0'  ' ISGF3_c%0')  (' BAD%0'  ' STAT2%0')  (' BAD%0'  ' CFLAR%0')  (' BAD%0'  ' SMAD2%0')  (' BAD%0'  ' MDM2_g%0')  (' BAD%0'  ' BAX%0')  (' BAD%0'  ' PRKACA%0')  (' BAD%0'  ' TGFB1%0')  (' BAD%0'  ' MAP3K8%0')  (' BAD%0'  ' TSC_f%0')  (' BAD%0'  ' SMAD4%0')  (' BAD%0'  ' MAP3K5%0')  (' BAD%0'  ' AKT1S1%0')  (' BAD%0'  ' SKI%0')  (' BAD%0'  ' SMAD3%0')  (' BAD%0'  ' MAPKAPK2%0')  (' BAD%0'  ' DUSP1_g%0')  (' BAD%0'  ' MSK_f%0')  (' BAD%0'  ' GRAP2%0')  (' BAD%0'  ' TAB_f%0')  (' BAD%0'  ' ATF2%0')  (' BAD%0'  ' SMAD5%0')  (' BAD%0'  ' SMAD1%0')  (' BAD%0'  ' FOS%0')  (' BAD%0'  ' JUN%0')  (' BAD%0'  ' MAP3K7%0')  (' BAD%0'  ' NLK%0')  (' BAD%0'  ' SMAD7_g%0')  (' BAD%0'  ' SMAD6_g%0')  (' BAD%0'  ' AP1_c%0')  (' BAD%0'  ' ACVR1%0')  (' BAD%0'  ' PTPN6%0')  (' BAD%0'  ' CDC42%0')  (' BAD%0'  ' GRB2%0')  (' BAD%0'  ' TGFBR1%0')  (' BAD%0'  ' SMURF1%0')  (' BAD%0'  ' SMURF2%0')  (' BAD%0'  ' RHOA%0')  (' BAD%0'  ' BMPR2%0')  (' BAD%0'  ' PARD6A%0')  (' BAD%0'  ' DAAM1%0')  (' BAD%0'  ' SFRP1_g%0')  (' BAD%0'  ' PPM1A%0')  (' BAD%0'  ' CFL_f%0')  (' BAD%0'  ' PAK1%0')  (' BAD%0'  ' MAP3K11%0')  (' BAD%0'  ' MAP3K4%0')  (' BAD%0'  ' LIMK1%0')  (' BAD%0'  ' ROCK1%0')  (' BAD%0'  ' ITCH%0')  (' BAD%0'  ' ARHGAP24%0')  (' BAD%0'  ' TIAM1%0')  (' BAD%0'  ' RND3%0')  (' BAD%0'  ' MAPK8IP3%0')  (' BAD%0'  ' MXD1%0')  (' BAD%0'  ' PIP3%0')  (' MAP3K5%0'  ' SRC%0')  (' MAP3K5%0'  ' CSK%0')  (' MAP3K5%0'  ' CHUK%0')  (' MAP3K5%0'  ' RAC_f%0')  (' MAP3K5%0'  ' DUSP1%0')  (' MAP3K5%0'  ' TGFBR2%0')  (' MAP3K5%0'  ' ILR_f%0')  (' MAP3K5%0'  ' SYK%0')  (' MAP3K5%0'  ' IRAK1%0')  (' MAP3K5%0'  ' SHC1%0')  (' MAP3K5%0'  ' JAK_f%0')  (' MAP3K5%0'  ' CBPp300_c%0')  (' MAP3K5%0'  ' SKP2%0')  (' MAP3K5%0'  ' TP53%0')  (' MAP3K5%0'  ' SMAD7%0')  (' MAP3K5%0'  ' SMAD6%0')  (' MAP3K5%0'  ' DKK_f%0')  (' MAP3K5%0'  ' FOXO_f%0')  (' MAP3K5%0'  ' TCF7_f%0')  (' MAP3K5%0'  ' DKK_g%0')  (' MAP3K5%0'  ' MYC%0')  (' MAP3K5%0'  ' CCND1%0')  (' MAP3K5%0'  ' EGR1%0')  (' MAP3K5%0'  ' MMP_f%0')  (' MAP3K5%0'  ' PTEN_g%0')  (' MAP3K5%0'  ' RTPK_f%0')  (' MAP3K5%0'  ' CTNNB1%0')  (' MAP3K5%0'  'LEF1%0')  (' MAP3K5%0'  'SFRP1%0')  (' MAP3K5%0'  'FZD_f%0')  (' MAP3K5%0'  ' CASP8%0')  (' MAP3K5%0'  ' REL_f%0')  (' MAP3K5%0'  ' NFKB_f%0')  (' MAP3K5%0'  ' DVL_f%0')  (' MAP3K5%0'  ' LRP_f%0')  (' MAP3K5%0'  ' BTRC%0')  (' MAP3K5%0'  ' CK1_f%0')  (' MAP3K5%0'  ' AXIN1%0')  (' MAP3K5%0'  ' mTORC2_c%0')  (' MAP3K5%0'  ' PDPK1%0')  (' MAP3K5%0'  ' MEK_f%0')  (' MAP3K5%0'  ' CYCS%0')  (' MAP3K5%0'  ' CASP9%0')  (' MAP3K5%0'  ' GSK3_f%0')  (' MAP3K5%0'  ' IRS1%0')  (' MAP3K5%0'  ' MDM2%0')  (' MAP3K5%0'  ' AKT_f%0')  (' MAP3K5%0'  ' BCL2%0')  (' MAP3K5%0'  ' RAF_f%0')  (' MAP3K5%0'  ' mTORC1_c%0')  (' MAP3K5%0'  ' RHEB%0')  (' MAP3K5%0'  ' RTPK_g%0')  (' MAP3K5%0'  ' PTEN%0')  (' MAP3K5%0'  ' CASP3%0')  (' MAP3K5%0'  ' PIK3CA%0')  (' MAP3K5%0'  ' CREBBP%0')  (' MAP3K5%0'  ' PTPN11%0')  (' MAP3K5%0'  ' KRAS%0')  (' MAP3K5%0'  ' MAP2K4%0')  (' MAP3K5%0'  ' MAP2K7%0')  (' MAP3K5%0'  ' MAPK14%0')  (' MAP3K5%0'  ' JNK_f%0')  (' MAP3K5%0'  ' MAP2K3%0')  (' MAP3K5%0'  ' ERK_f%0')  (' MAP3K5%0'  ' LIF%0')  (' MAP3K5%0'  ' PPP1CA%0')  (' MAP3K5%0'  ' GAB_f%0')  (' MAP3K5%0'  ' SOS1%0')  (' MAP3K5%0'  ' PRKCA%0')  (' MAP3K5%0'  ' VAV1%0')  (' MAP3K5%0'  ' PLCG1%0')  (' MAP3K5%0'  ' PRKCD%0')  (' MAP3K5%0'  ' RSK_f%0')  (' MAP3K5%0'  ' S6K_f%0')  (' MAP3K5%0'  ' PLK1%0')  (' MAP3K5%0'  ' ILK%0')  (' MAP3K5%0'  ' SOCS1%0')  (' MAP3K5%0'  ' DUSP6%0')  (' MAP3K5%0'  ' STAT3%0')  (' MAP3K5%0'  ' LIMK2%0')  (' MAP3K5%0'  ' EP300%0')  (' MAP3K5%0'  ' STAT1%0')  (' MAP3K5%0'  ' IKBKB%0')  (' MAP3K5%0'  ' SRF%0')  (' MAP3K5%0'  ' PIAS1%0')  (' MAP3K5%0'  ' TRAF6%0')  (' MAP3K5%0'  ' SOCS1_g%0')  (' MAP3K5%0'  ' ISGF3_c%0')  (' MAP3K5%0'  ' STAT2%0')  (' MAP3K5%0'  ' CFLAR%0')  (' MAP3K5%0'  ' SMAD2%0')  (' MAP3K5%0'  ' MDM2_g%0')  (' MAP3K5%0'  ' BAX%0')  (' MAP3K5%0'  ' PRKACA%0')  (' MAP3K5%0'  ' TGFB1%0')  (' MAP3K5%0'  ' MAP3K8%0')  (' MAP3K5%0'  ' TSC_f%0')  (' MAP3K5%0'  ' SMAD4%0')  (' MAP3K5%0'  ' BAD%0')  (' MAP3K5%0'  ' AKT1S1%0')  (' MAP3K5%0'  ' SKI%0')  (' MAP3K5%0'  ' SMAD3%0')  (' MAP3K5%0'  ' MAPKAPK2%0')  (' MAP3K5%0'  ' DUSP1_g%0')  (' MAP3K5%0'  ' MSK_f%0')  (' MAP3K5%0'  ' GRAP2%0')  (' MAP3K5%0'  ' TAB_f%0')  (' MAP3K5%0'  ' ATF2%0')  (' MAP3K5%0'  ' SMAD5%0')  (' MAP3K5%0'  ' SMAD1%0')  (' MAP3K5%0'  ' FOS%0')  (' MAP3K5%0'  ' JUN%0')  (' MAP3K5%0'  ' MAP3K7%0')  (' MAP3K5%0'  ' NLK%0')  (' MAP3K5%0'  ' SMAD7_g%0')  (' MAP3K5%0'  ' SMAD6_g%0')  (' MAP3K5%0'  ' AP1_c%0')  (' MAP3K5%0'  ' ACVR1%0')  (' MAP3K5%0'  ' PTPN6%0')  (' MAP3K5%0'  ' CDC42%0')  (' MAP3K5%0'  ' GRB2%0')  (' MAP3K5%0'  ' TGFBR1%0')  (' MAP3K5%0'  ' SMURF1%0')  (' MAP3K5%0'  ' SMURF2%0')  (' MAP3K5%0'  ' RHOA%0')  (' MAP3K5%0'  ' BMPR2%0')  (' MAP3K5%0'  ' PARD6A%0')  (' MAP3K5%0'  ' DAAM1%0')  (' MAP3K5%0'  ' SFRP1_g%0')  (' MAP3K5%0'  ' PPM1A%0')  (' MAP3K5%0'  ' CFL_f%0')  (' MAP3K5%0'  ' PAK1%0')  (' MAP3K5%0'  ' MAP3K11%0')  (' MAP3K5%0'  ' MAP3K4%0')  (' MAP3K5%0'  ' LIMK1%0')  (' MAP3K5%0'  ' ROCK1%0')  (' MAP3K5%0'  ' ITCH%0')  (' MAP3K5%0'  ' ARHGAP24%0')  (' MAP3K5%0'  ' TIAM1%0')  (' MAP3K5%0'  ' RND3%0')  (' MAP3K5%0'  ' MAPK8IP3%0')  (' MAP3K5%0'  ' MXD1%0')  (' MAP3K5%0'  ' PIP3%0')  (' AKT1S1%0'  ' SRC%0')  (' AKT1S1%0'  ' CSK%0')  (' AKT1S1%0'  ' CHUK%0')  (' AKT1S1%0'  ' RAC_f%0')  (' AKT1S1%0'  ' DUSP1%0')  (' AKT1S1%0'  ' TGFBR2%0')  (' AKT1S1%0'  ' ILR_f%0')  (' AKT1S1%0'  ' SYK%0')  (' AKT1S1%0'  ' IRAK1%0')  (' AKT1S1%0'  ' SHC1%0')  (' AKT1S1%0'  ' JAK_f%0')  (' AKT1S1%0'  ' CBPp300_c%0')  (' AKT1S1%0'  ' SKP2%0')  (' AKT1S1%0'  ' TP53%0')  (' AKT1S1%0'  ' SMAD7%0')  (' AKT1S1%0'  ' SMAD6%0')  (' AKT1S1%0'  ' DKK_f%0')  (' AKT1S1%0'  ' FOXO_f%0')  (' AKT1S1%0'  ' TCF7_f%0')  (' AKT1S1%0'  ' DKK_g%0')  (' AKT1S1%0'  ' MYC%0')  (' AKT1S1%0'  ' CCND1%0')  (' AKT1S1%0'  ' EGR1%0')  (' AKT1S1%0'  ' MMP_f%0')  (' AKT1S1%0'  ' PTEN_g%0')  (' AKT1S1%0'  ' RTPK_f%0')  (' AKT1S1%0'  ' CTNNB1%0')  (' AKT1S1%0'  'LEF1%0')  (' AKT1S1%0'  'SFRP1%0')  (' AKT1S1%0'  'FZD_f%0')  (' AKT1S1%0'  ' CASP8%0')  (' AKT1S1%0'  ' REL_f%0')  (' AKT1S1%0'  ' NFKB_f%0')  (' AKT1S1%0'  ' DVL_f%0')  (' AKT1S1%0'  ' LRP_f%0')  (' AKT1S1%0'  ' BTRC%0')  (' AKT1S1%0'  ' CK1_f%0')  (' AKT1S1%0'  ' AXIN1%0')  (' AKT1S1%0'  ' mTORC2_c%0')  (' AKT1S1%0'  ' PDPK1%0')  (' AKT1S1%0'  ' MEK_f%0')  (' AKT1S1%0'  ' CYCS%0')  (' AKT1S1%0'  ' CASP9%0')  (' AKT1S1%0'  ' GSK3_f%0')  (' AKT1S1%0'  ' IRS1%0')  (' AKT1S1%0'  ' MDM2%0')  (' AKT1S1%0'  ' AKT_f%0')  (' AKT1S1%0'  ' BCL2%0')  (' AKT1S1%0'  ' RAF_f%0')  (' AKT1S1%0'  ' mTORC1_c%0')  (' AKT1S1%0'  ' RHEB%0')  (' AKT1S1%0'  ' RTPK_g%0')  (' AKT1S1%0'  ' PTEN%0')  (' AKT1S1%0'  ' CASP3%0')  (' AKT1S1%0'  ' PIK3CA%0')  (' AKT1S1%0'  ' CREBBP%0')  (' AKT1S1%0'  ' PTPN11%0')  (' AKT1S1%0'  ' KRAS%0')  (' AKT1S1%0'  ' MAP2K4%0')  (' AKT1S1%0'  ' MAP2K7%0')  (' AKT1S1%0'  ' MAPK14%0')  (' AKT1S1%0'  ' JNK_f%0')  (' AKT1S1%0'  ' MAP2K3%0')  (' AKT1S1%0'  ' ERK_f%0')  (' AKT1S1%0'  ' LIF%0')  (' AKT1S1%0'  ' PPP1CA%0')  (' AKT1S1%0'  ' GAB_f%0')  (' AKT1S1%0'  ' SOS1%0')  (' AKT1S1%0'  ' PRKCA%0')  (' AKT1S1%0'  ' VAV1%0')  (' AKT1S1%0'  ' PLCG1%0')  (' AKT1S1%0'  ' PRKCD%0')  (' AKT1S1%0'  ' RSK_f%0')  (' AKT1S1%0'  ' S6K_f%0')  (' AKT1S1%0'  ' PLK1%0')  (' AKT1S1%0'  ' ILK%0')  (' AKT1S1%0'  ' SOCS1%0')  (' AKT1S1%0'  ' DUSP6%0')  (' AKT1S1%0'  ' STAT3%0')  (' AKT1S1%0'  ' LIMK2%0')  (' AKT1S1%0'  ' EP300%0')  (' AKT1S1%0'  ' STAT1%0')  (' AKT1S1%0'  ' IKBKB%0')  (' AKT1S1%0'  ' SRF%0')  (' AKT1S1%0'  ' PIAS1%0')  (' AKT1S1%0'  ' TRAF6%0')  (' AKT1S1%0'  ' SOCS1_g%0')  (' AKT1S1%0'  ' ISGF3_c%0')  (' AKT1S1%0'  ' STAT2%0')  (' AKT1S1%0'  ' CFLAR%0')  (' AKT1S1%0'  ' SMAD2%0')  (' AKT1S1%0'  ' MDM2_g%0')  (' AKT1S1%0'  ' BAX%0')  (' AKT1S1%0'  ' PRKACA%0')  (' AKT1S1%0'  ' TGFB1%0')  (' AKT1S1%0'  ' MAP3K8%0')  (' AKT1S1%0'  ' TSC_f%0')  (' AKT1S1%0'  ' SMAD4%0')  (' AKT1S1%0'  ' BAD%0')  (' AKT1S1%0'  ' MAP3K5%0')  (' AKT1S1%0'  ' SKI%0')  (' AKT1S1%0'  ' SMAD3%0')  (' AKT1S1%0'  ' MAPKAPK2%0')  (' AKT1S1%0'  ' DUSP1_g%0')  (' AKT1S1%0'  ' MSK_f%0')  (' AKT1S1%0'  ' GRAP2%0')  (' AKT1S1%0'  ' TAB_f%0')  (' AKT1S1%0'  ' ATF2%0')  (' AKT1S1%0'  ' SMAD5%0')  (' AKT1S1%0'  ' SMAD1%0')  (' AKT1S1%0'  ' FOS%0')  (' AKT1S1%0'  ' JUN%0')  (' AKT1S1%0'  ' MAP3K7%0')  (' AKT1S1%0'  ' NLK%0')  (' AKT1S1%0'  ' SMAD7_g%0')  (' AKT1S1%0'  ' SMAD6_g%0')  (' AKT1S1%0'  ' AP1_c%0')  (' AKT1S1%0'  ' ACVR1%0')  (' AKT1S1%0'  ' PTPN6%0')  (' AKT1S1%0'  ' CDC42%0')  (' AKT1S1%0'  ' GRB2%0')  (' AKT1S1%0'  ' TGFBR1%0')  (' AKT1S1%0'  ' SMURF1%0')  (' AKT1S1%0'  ' SMURF2%0')  (' AKT1S1%0'  ' RHOA%0')  (' AKT1S1%0'  ' BMPR2%0')  (' AKT1S1%0'  ' PARD6A%0')  (' AKT1S1%0'  ' DAAM1%0')  (' AKT1S1%0'  ' SFRP1_g%0')  (' AKT1S1%0'  ' PPM1A%0')  (' AKT1S1%0'  ' CFL_f%0')  (' AKT1S1%0'  ' PAK1%0')  (' AKT1S1%0'  ' MAP3K11%0')  (' AKT1S1%0'  ' MAP3K4%0')  (' AKT1S1%0'  ' LIMK1%0')  (' AKT1S1%0'  ' ROCK1%0')  (' AKT1S1%0'  ' ITCH%0')  (' AKT1S1%0'  ' ARHGAP24%0')  (' AKT1S1%0'  ' TIAM1%0')  (' AKT1S1%0'  ' RND3%0')  (' AKT1S1%0'  ' MAPK8IP3%0')  (' AKT1S1%0'  ' MXD1%0')  (' AKT1S1%0'  ' PIP3%0')  (' SKI%0'  ' SRC%0')  (' SKI%0'  ' CSK%0')  (' SKI%0'  ' CHUK%0')  (' SKI%0'  ' RAC_f%0')  (' SKI%0'  ' DUSP1%0')  (' SKI%0'  ' TGFBR2%0')  (' SKI%0'  ' ILR_f%0')  (' SKI%0'  ' SYK%0')  (' SKI%0'  ' IRAK1%0')  (' SKI%0'  ' SHC1%0')  (' SKI%0'  ' JAK_f%0')  (' SKI%0'  ' CBPp300_c%0')  (' SKI%0'  ' SKP2%0')  (' SKI%0'  ' TP53%0')  (' SKI%0'  ' SMAD7%0')  (' SKI%0'  ' SMAD6%0')  (' SKI%0'  ' DKK_f%0')  (' SKI%0'  ' FOXO_f%0')  (' SKI%0'  ' TCF7_f%0')  (' SKI%0'  ' DKK_g%0')  (' SKI%0'  ' MYC%0')  (' SKI%0'  ' CCND1%0')  (' SKI%0'  ' EGR1%0')  (' SKI%0'  ' MMP_f%0')  (' SKI%0'  ' PTEN_g%0')  (' SKI%0'  ' RTPK_f%0')  (' SKI%0'  ' CTNNB1%0')  (' SKI%0'  'LEF1%0')  (' SKI%0'  'SFRP1%0')  (' SKI%0'  'FZD_f%0')  (' SKI%0'  ' CASP8%0')  (' SKI%0'  ' REL_f%0')  (' SKI%0'  ' NFKB_f%0')  (' SKI%0'  ' DVL_f%0')  (' SKI%0'  ' LRP_f%0')  (' SKI%0'  ' BTRC%0')  (' SKI%0'  ' CK1_f%0')  (' SKI%0'  ' AXIN1%0')  (' SKI%0'  ' mTORC2_c%0')  (' SKI%0'  ' PDPK1%0')  (' SKI%0'  ' MEK_f%0')  (' SKI%0'  ' CYCS%0')  (' SKI%0'  ' CASP9%0')  (' SKI%0'  ' GSK3_f%0')  (' SKI%0'  ' IRS1%0')  (' SKI%0'  ' MDM2%0')  (' SKI%0'  ' AKT_f%0')  (' SKI%0'  ' BCL2%0')  (' SKI%0'  ' RAF_f%0')  (' SKI%0'  ' mTORC1_c%0')  (' SKI%0'  ' RHEB%0')  (' SKI%0'  ' RTPK_g%0')  (' SKI%0'  ' PTEN%0')  (' SKI%0'  ' CASP3%0')  (' SKI%0'  ' PIK3CA%0')  (' SKI%0'  ' CREBBP%0')  (' SKI%0'  ' PTPN11%0')  (' SKI%0'  ' KRAS%0')  (' SKI%0'  ' MAP2K4%0')  (' SKI%0'  ' MAP2K7%0')  (' SKI%0'  ' MAPK14%0')  (' SKI%0'  ' JNK_f%0')  (' SKI%0'  ' MAP2K3%0')  (' SKI%0'  ' ERK_f%0')  (' SKI%0'  ' LIF%0')  (' SKI%0'  ' PPP1CA%0')  (' SKI%0'  ' GAB_f%0')  (' SKI%0'  ' SOS1%0')  (' SKI%0'  ' PRKCA%0')  (' SKI%0'  ' VAV1%0')  (' SKI%0'  ' PLCG1%0')  (' SKI%0'  ' PRKCD%0')  (' SKI%0'  ' RSK_f%0')  (' SKI%0'  ' S6K_f%0')  (' SKI%0'  ' PLK1%0')  (' SKI%0'  ' ILK%0')  (' SKI%0'  ' SOCS1%0')  (' SKI%0'  ' DUSP6%0')  (' SKI%0'  ' STAT3%0')  (' SKI%0'  ' LIMK2%0')  (' SKI%0'  ' EP300%0')  (' SKI%0'  ' STAT1%0')  (' SKI%0'  ' IKBKB%0')  (' SKI%0'  ' SRF%0')  (' SKI%0'  ' PIAS1%0')  (' SKI%0'  ' TRAF6%0')  (' SKI%0'  ' SOCS1_g%0')  (' SKI%0'  ' ISGF3_c%0')  (' SKI%0'  ' STAT2%0')  (' SKI%0'  ' CFLAR%0')  (' SKI%0'  ' SMAD2%0')  (' SKI%0'  ' MDM2_g%0')  (' SKI%0'  ' BAX%0')  (' SKI%0'  ' PRKACA%0')  (' SKI%0'  ' TGFB1%0')  (' SKI%0'  ' MAP3K8%0')  (' SKI%0'  ' TSC_f%0')  (' SKI%0'  ' SMAD4%0')  (' SKI%0'  ' BAD%0')  (' SKI%0'  ' MAP3K5%0')  (' SKI%0'  ' AKT1S1%0')  (' SKI%0'  ' SMAD3%0')  (' SKI%0'  ' MAPKAPK2%0')  (' SKI%0'  ' DUSP1_g%0')  (' SKI%0'  ' MSK_f%0')  (' SKI%0'  ' GRAP2%0')  (' SKI%0'  ' TAB_f%0')  (' SKI%0'  ' ATF2%0')  (' SKI%0'  ' SMAD5%0')  (' SKI%0'  ' SMAD1%0')  (' SKI%0'  ' FOS%0')  (' SKI%0'  ' JUN%0')  (' SKI%0'  ' MAP3K7%0')  (' SKI%0'  ' NLK%0')  (' SKI%0'  ' SMAD7_g%0')  (' SKI%0'  ' SMAD6_g%0')  (' SKI%0'  ' AP1_c%0')  (' SKI%0'  ' ACVR1%0')  (' SKI%0'  ' PTPN6%0')  (' SKI%0'  ' CDC42%0')  (' SKI%0'  ' GRB2%0')  (' SKI%0'  ' TGFBR1%0')  (' SKI%0'  ' SMURF1%0')  (' SKI%0'  ' SMURF2%0')  (' SKI%0'  ' RHOA%0')  (' SKI%0'  ' BMPR2%0')  (' SKI%0'  ' PARD6A%0')  (' SKI%0'  ' DAAM1%0')  (' SKI%0'  ' SFRP1_g%0')  (' SKI%0'  ' PPM1A%0')  (' SKI%0'  ' CFL_f%0')  (' SKI%0'  ' PAK1%0')  (' SKI%0'  ' MAP3K11%0')  (' SKI%0'  ' MAP3K4%0')  (' SKI%0'  ' LIMK1%0')  (' SKI%0'  ' ROCK1%0')  (' SKI%0'  ' ITCH%0')  (' SKI%0'  ' ARHGAP24%0')  (' SKI%0'  ' TIAM1%0')  (' SKI%0'  ' RND3%0')  (' SKI%0'  ' MAPK8IP3%0')  (' SKI%0'  ' MXD1%0')  (' SKI%0'  ' PIP3%0')  (' SMAD3%0'  ' SRC%0')  (' SMAD3%0'  ' CSK%0')  (' SMAD3%0'  ' CHUK%0')  (' SMAD3%0'  ' RAC_f%0')  (' SMAD3%0'  ' DUSP1%0')  (' SMAD3%0'  ' TGFBR2%0')  (' SMAD3%0'  ' ILR_f%0')  (' SMAD3%0'  ' SYK%0')  (' SMAD3%0'  ' IRAK1%0')  (' SMAD3%0'  ' SHC1%0')  (' SMAD3%0'  ' JAK_f%0')  (' SMAD3%0'  ' CBPp300_c%0')  (' SMAD3%0'  ' SKP2%0')  (' SMAD3%0'  ' TP53%0')  (' SMAD3%0'  ' SMAD7%0')  (' SMAD3%0'  ' SMAD6%0')  (' SMAD3%0'  ' DKK_f%0')  (' SMAD3%0'  ' FOXO_f%0')  (' SMAD3%0'  ' TCF7_f%0')  (' SMAD3%0'  ' DKK_g%0')  (' SMAD3%0'  ' MYC%0')  (' SMAD3%0'  ' CCND1%0')  (' SMAD3%0'  ' EGR1%0')  (' SMAD3%0'  ' MMP_f%0')  (' SMAD3%0'  ' PTEN_g%0')  (' SMAD3%0'  ' RTPK_f%0')  (' SMAD3%0'  ' CTNNB1%0')  (' SMAD3%0'  'LEF1%0')  (' SMAD3%0'  'SFRP1%0')  (' SMAD3%0'  'FZD_f%0')  (' SMAD3%0'  ' CASP8%0')  (' SMAD3%0'  ' REL_f%0')  (' SMAD3%0'  ' NFKB_f%0')  (' SMAD3%0'  ' DVL_f%0')  (' SMAD3%0'  ' LRP_f%0')  (' SMAD3%0'  ' BTRC%0')  (' SMAD3%0'  ' CK1_f%0')  (' SMAD3%0'  ' AXIN1%0')  (' SMAD3%0'  ' mTORC2_c%0')  (' SMAD3%0'  ' PDPK1%0')  (' SMAD3%0'  ' MEK_f%0')  (' SMAD3%0'  ' CYCS%0')  (' SMAD3%0'  ' CASP9%0')  (' SMAD3%0'  ' GSK3_f%0')  (' SMAD3%0'  ' IRS1%0')  (' SMAD3%0'  ' MDM2%0')  (' SMAD3%0'  ' AKT_f%0')  (' SMAD3%0'  ' BCL2%0')  (' SMAD3%0'  ' RAF_f%0')  (' SMAD3%0'  ' mTORC1_c%0')  (' SMAD3%0'  ' RHEB%0')  (' SMAD3%0'  ' RTPK_g%0')  (' SMAD3%0'  ' PTEN%0')  (' SMAD3%0'  ' CASP3%0')  (' SMAD3%0'  ' PIK3CA%0')  (' SMAD3%0'  ' CREBBP%0')  (' SMAD3%0'  ' PTPN11%0')  (' SMAD3%0'  ' KRAS%0')  (' SMAD3%0'  ' MAP2K4%0')  (' SMAD3%0'  ' MAP2K7%0')  (' SMAD3%0'  ' MAPK14%0')  (' SMAD3%0'  ' JNK_f%0')  (' SMAD3%0'  ' MAP2K3%0')  (' SMAD3%0'  ' ERK_f%0')  (' SMAD3%0'  ' LIF%0')  (' SMAD3%0'  ' PPP1CA%0')  (' SMAD3%0'  ' GAB_f%0')  (' SMAD3%0'  ' SOS1%0')  (' SMAD3%0'  ' PRKCA%0')  (' SMAD3%0'  ' VAV1%0')  (' SMAD3%0'  ' PLCG1%0')  (' SMAD3%0'  ' PRKCD%0')  (' SMAD3%0'  ' RSK_f%0')  (' SMAD3%0'  ' S6K_f%0')  (' SMAD3%0'  ' PLK1%0')  (' SMAD3%0'  ' ILK%0')  (' SMAD3%0'  ' SOCS1%0')  (' SMAD3%0'  ' DUSP6%0')  (' SMAD3%0'  ' STAT3%0')  (' SMAD3%0'  ' LIMK2%0')  (' SMAD3%0'  ' EP300%0')  (' SMAD3%0'  ' STAT1%0')  (' SMAD3%0'  ' IKBKB%0')  (' SMAD3%0'  ' SRF%0')  (' SMAD3%0'  ' PIAS1%0')  (' SMAD3%0'  ' TRAF6%0')  (' SMAD3%0'  ' SOCS1_g%0')  (' SMAD3%0'  ' ISGF3_c%0')  (' SMAD3%0'  ' STAT2%0')  (' SMAD3%0'  ' CFLAR%0')  (' SMAD3%0'  ' SMAD2%0')  (' SMAD3%0'  ' MDM2_g%0')  (' SMAD3%0'  ' BAX%0')  (' SMAD3%0'  ' PRKACA%0')  (' SMAD3%0'  ' TGFB1%0')  (' SMAD3%0'  ' MAP3K8%0')  (' SMAD3%0'  ' TSC_f%0')  (' SMAD3%0'  ' SMAD4%0')  (' SMAD3%0'  ' BAD%0')  (' SMAD3%0'  ' MAP3K5%0')  (' SMAD3%0'  ' AKT1S1%0')  (' SMAD3%0'  ' SKI%0')  (' SMAD3%0'  ' MAPKAPK2%0')  (' SMAD3%0'  ' DUSP1_g%0')  (' SMAD3%0'  ' MSK_f%0')  (' SMAD3%0'  ' GRAP2%0')  (' SMAD3%0'  ' TAB_f%0')  (' SMAD3%0'  ' ATF2%0')  (' SMAD3%0'  ' SMAD5%0')  (' SMAD3%0'  ' SMAD1%0')  (' SMAD3%0'  ' FOS%0')  (' SMAD3%0'  ' JUN%0')  (' SMAD3%0'  ' MAP3K7%0')  (' SMAD3%0'  ' NLK%0')  (' SMAD3%0'  ' SMAD7_g%0')  (' SMAD3%0'  ' SMAD6_g%0')  (' SMAD3%0'  ' AP1_c%0')  (' SMAD3%0'  ' ACVR1%0')  (' SMAD3%0'  ' PTPN6%0')  (' SMAD3%0'  ' CDC42%0')  (' SMAD3%0'  ' GRB2%0')  (' SMAD3%0'  ' TGFBR1%0')  (' SMAD3%0'  ' SMURF1%0')  (' SMAD3%0'  ' SMURF2%0')  (' SMAD3%0'  ' RHOA%0')  (' SMAD3%0'  ' BMPR2%0')  (' SMAD3%0'  ' PARD6A%0')  (' SMAD3%0'  ' DAAM1%0')  (' SMAD3%0'  ' SFRP1_g%0')  (' SMAD3%0'  ' PPM1A%0')  (' SMAD3%0'  ' CFL_f%0')  (' SMAD3%0'  ' PAK1%0')  (' SMAD3%0'  ' MAP3K11%0')  (' SMAD3%0'  ' MAP3K4%0')  (' SMAD3%0'  ' LIMK1%0')  (' SMAD3%0'  ' ROCK1%0')  (' SMAD3%0'  ' ITCH%0')  (' SMAD3%0'  ' ARHGAP24%0')  (' SMAD3%0'  ' TIAM1%0')  (' SMAD3%0'  ' RND3%0')  (' SMAD3%0'  ' MAPK8IP3%0')  (' SMAD3%0'  ' MXD1%0')  (' SMAD3%0'  ' PIP3%0')  (' MAPKAPK2%0'  ' SRC%0')  (' MAPKAPK2%0'  ' CSK%0')  (' MAPKAPK2%0'  ' CHUK%0')  (' MAPKAPK2%0'  ' RAC_f%0')  (' MAPKAPK2%0'  ' DUSP1%0')  (' MAPKAPK2%0'  ' TGFBR2%0')  (' MAPKAPK2%0'  ' ILR_f%0')  (' MAPKAPK2%0'  ' SYK%0')  (' MAPKAPK2%0'  ' IRAK1%0')  (' MAPKAPK2%0'  ' SHC1%0')  (' MAPKAPK2%0'  ' JAK_f%0')  (' MAPKAPK2%0'  ' CBPp300_c%0')  (' MAPKAPK2%0'  ' SKP2%0')  (' MAPKAPK2%0'  ' TP53%0')  (' MAPKAPK2%0'  ' SMAD7%0')  (' MAPKAPK2%0'  ' SMAD6%0')  (' MAPKAPK2%0'  ' DKK_f%0')  (' MAPKAPK2%0'  ' FOXO_f%0')  (' MAPKAPK2%0'  ' TCF7_f%0')  (' MAPKAPK2%0'  ' DKK_g%0')  (' MAPKAPK2%0'  ' MYC%0')  (' MAPKAPK2%0'  ' CCND1%0')  (' MAPKAPK2%0'  ' EGR1%0')  (' MAPKAPK2%0'  ' MMP_f%0')  (' MAPKAPK2%0'  ' PTEN_g%0')  (' MAPKAPK2%0'  ' RTPK_f%0')  (' MAPKAPK2%0'  ' CTNNB1%0')  (' MAPKAPK2%0'  'LEF1%0')  (' MAPKAPK2%0'  'SFRP1%0')  (' MAPKAPK2%0'  'FZD_f%0')  (' MAPKAPK2%0'  ' CASP8%0')  (' MAPKAPK2%0'  ' REL_f%0')  (' MAPKAPK2%0'  ' NFKB_f%0')  (' MAPKAPK2%0'  ' DVL_f%0')  (' MAPKAPK2%0'  ' LRP_f%0')  (' MAPKAPK2%0'  ' BTRC%0')  (' MAPKAPK2%0'  ' CK1_f%0')  (' MAPKAPK2%0'  ' AXIN1%0')  (' MAPKAPK2%0'  ' mTORC2_c%0')  (' MAPKAPK2%0'  ' PDPK1%0')  (' MAPKAPK2%0'  ' MEK_f%0')  (' MAPKAPK2%0'  ' CYCS%0')  (' MAPKAPK2%0'  ' CASP9%0')  (' MAPKAPK2%0'  ' GSK3_f%0')  (' MAPKAPK2%0'  ' IRS1%0')  (' MAPKAPK2%0'  ' MDM2%0')  (' MAPKAPK2%0'  ' AKT_f%0')  (' MAPKAPK2%0'  ' BCL2%0')  (' MAPKAPK2%0'  ' RAF_f%0')  (' MAPKAPK2%0'  ' mTORC1_c%0')  (' MAPKAPK2%0'  ' RHEB%0')  (' MAPKAPK2%0'  ' RTPK_g%0')  (' MAPKAPK2%0'  ' PTEN%0')  (' MAPKAPK2%0'  ' CASP3%0')  (' MAPKAPK2%0'  ' PIK3CA%0')  (' MAPKAPK2%0'  ' CREBBP%0')  (' MAPKAPK2%0'  ' PTPN11%0')  (' MAPKAPK2%0'  ' KRAS%0')  (' MAPKAPK2%0'  ' MAP2K4%0')  (' MAPKAPK2%0'  ' MAP2K7%0')  (' MAPKAPK2%0'  ' MAPK14%0')  (' MAPKAPK2%0'  ' JNK_f%0')  (' MAPKAPK2%0'  ' MAP2K3%0')  (' MAPKAPK2%0'  ' ERK_f%0')  (' MAPKAPK2%0'  ' LIF%0')  (' MAPKAPK2%0'  ' PPP1CA%0')  (' MAPKAPK2%0'  ' GAB_f%0')  (' MAPKAPK2%0'  ' SOS1%0')  (' MAPKAPK2%0'  ' PRKCA%0')  (' MAPKAPK2%0'  ' VAV1%0')  (' MAPKAPK2%0'  ' PLCG1%0')  (' MAPKAPK2%0'  ' PRKCD%0')  (' MAPKAPK2%0'  ' RSK_f%0')  (' MAPKAPK2%0'  ' S6K_f%0')  (' MAPKAPK2%0'  ' PLK1%0')  (' MAPKAPK2%0'  ' ILK%0')  (' MAPKAPK2%0'  ' SOCS1%0')  (' MAPKAPK2%0'  ' DUSP6%0')  (' MAPKAPK2%0'  ' STAT3%0')  (' MAPKAPK2%0'  ' LIMK2%0')  (' MAPKAPK2%0'  ' EP300%0')  (' MAPKAPK2%0'  ' STAT1%0')  (' MAPKAPK2%0'  ' IKBKB%0')  (' MAPKAPK2%0'  ' SRF%0')  (' MAPKAPK2%0'  ' PIAS1%0')  (' MAPKAPK2%0'  ' TRAF6%0')  (' MAPKAPK2%0'  ' SOCS1_g%0')  (' MAPKAPK2%0'  ' ISGF3_c%0')  (' MAPKAPK2%0'  ' STAT2%0')  (' MAPKAPK2%0'  ' CFLAR%0')  (' MAPKAPK2%0'  ' SMAD2%0')  (' MAPKAPK2%0'  ' MDM2_g%0')  (' MAPKAPK2%0'  ' BAX%0')  (' MAPKAPK2%0'  ' PRKACA%0')  (' MAPKAPK2%0'  ' TGFB1%0')  (' MAPKAPK2%0'  ' MAP3K8%0')  (' MAPKAPK2%0'  ' TSC_f%0')  (' MAPKAPK2%0'  ' SMAD4%0')  (' MAPKAPK2%0'  ' BAD%0')  (' MAPKAPK2%0'  ' MAP3K5%0')  (' MAPKAPK2%0'  ' AKT1S1%0')  (' MAPKAPK2%0'  ' SKI%0')  (' MAPKAPK2%0'  ' SMAD3%0')  (' MAPKAPK2%0'  ' DUSP1_g%0')  (' MAPKAPK2%0'  ' MSK_f%0')  (' MAPKAPK2%0'  ' GRAP2%0')  (' MAPKAPK2%0'  ' TAB_f%0')  (' MAPKAPK2%0'  ' ATF2%0')  (' MAPKAPK2%0'  ' SMAD5%0')  (' MAPKAPK2%0'  ' SMAD1%0')  (' MAPKAPK2%0'  ' FOS%0')  (' MAPKAPK2%0'  ' JUN%0')  (' MAPKAPK2%0'  ' MAP3K7%0')  (' MAPKAPK2%0'  ' NLK%0')  (' MAPKAPK2%0'  ' SMAD7_g%0')  (' MAPKAPK2%0'  ' SMAD6_g%0')  (' MAPKAPK2%0'  ' AP1_c%0')  (' MAPKAPK2%0'  ' ACVR1%0')  (' MAPKAPK2%0'  ' PTPN6%0')  (' MAPKAPK2%0'  ' CDC42%0')  (' MAPKAPK2%0'  ' GRB2%0')  (' MAPKAPK2%0'  ' TGFBR1%0')  (' MAPKAPK2%0'  ' SMURF1%0')  (' MAPKAPK2%0'  ' SMURF2%0')  (' MAPKAPK2%0'  ' RHOA%0')  (' MAPKAPK2%0'  ' BMPR2%0')  (' MAPKAPK2%0'  ' PARD6A%0')  (' MAPKAPK2%0'  ' DAAM1%0')  (' MAPKAPK2%0'  ' SFRP1_g%0')  (' MAPKAPK2%0'  ' PPM1A%0')  (' MAPKAPK2%0'  ' CFL_f%0')  (' MAPKAPK2%0'  ' PAK1%0')  (' MAPKAPK2%0'  ' MAP3K11%0')  (' MAPKAPK2%0'  ' MAP3K4%0')  (' MAPKAPK2%0'  ' LIMK1%0')  (' MAPKAPK2%0'  ' ROCK1%0')  (' MAPKAPK2%0'  ' ITCH%0')  (' MAPKAPK2%0'  ' ARHGAP24%0')  (' MAPKAPK2%0'  ' TIAM1%0')  (' MAPKAPK2%0'  ' RND3%0')  (' MAPKAPK2%0'  ' MAPK8IP3%0')  (' MAPKAPK2%0'  ' MXD1%0')  (' MAPKAPK2%0'  ' PIP3%0')  (' DUSP1_g%0'  ' SRC%0')  (' DUSP1_g%0'  ' CSK%0')  (' DUSP1_g%0'  ' CHUK%0')  (' DUSP1_g%0'  ' RAC_f%0')  (' DUSP1_g%0'  ' DUSP1%0')  (' DUSP1_g%0'  ' TGFBR2%0')  (' DUSP1_g%0'  ' ILR_f%0')  (' DUSP1_g%0'  ' SYK%0')  (' DUSP1_g%0'  ' IRAK1%0')  (' DUSP1_g%0'  ' SHC1%0')  (' DUSP1_g%0'  ' JAK_f%0')  (' DUSP1_g%0'  ' CBPp300_c%0')  (' DUSP1_g%0'  ' SKP2%0')  (' DUSP1_g%0'  ' TP53%0')  (' DUSP1_g%0'  ' SMAD7%0')  (' DUSP1_g%0'  ' SMAD6%0')  (' DUSP1_g%0'  ' DKK_f%0')  (' DUSP1_g%0'  ' FOXO_f%0')  (' DUSP1_g%0'  ' TCF7_f%0')  (' DUSP1_g%0'  ' DKK_g%0')  (' DUSP1_g%0'  ' MYC%0')  (' DUSP1_g%0'  ' CCND1%0')  (' DUSP1_g%0'  ' EGR1%0')  (' DUSP1_g%0'  ' MMP_f%0')  (' DUSP1_g%0'  ' PTEN_g%0')  (' DUSP1_g%0'  ' RTPK_f%0')  (' DUSP1_g%0'  ' CTNNB1%0')  (' DUSP1_g%0'  'LEF1%0')  (' DUSP1_g%0'  'SFRP1%0')  (' DUSP1_g%0'  'FZD_f%0')  (' DUSP1_g%0'  ' CASP8%0')  (' DUSP1_g%0'  ' REL_f%0')  (' DUSP1_g%0'  ' NFKB_f%0')  (' DUSP1_g%0'  ' DVL_f%0')  (' DUSP1_g%0'  ' LRP_f%0')  (' DUSP1_g%0'  ' BTRC%0')  (' DUSP1_g%0'  ' CK1_f%0')  (' DUSP1_g%0'  ' AXIN1%0')  (' DUSP1_g%0'  ' mTORC2_c%0')  (' DUSP1_g%0'  ' PDPK1%0')  (' DUSP1_g%0'  ' MEK_f%0')  (' DUSP1_g%0'  ' CYCS%0')  (' DUSP1_g%0'  ' CASP9%0')  (' DUSP1_g%0'  ' GSK3_f%0')  (' DUSP1_g%0'  ' IRS1%0')  (' DUSP1_g%0'  ' MDM2%0')  (' DUSP1_g%0'  ' AKT_f%0')  (' DUSP1_g%0'  ' BCL2%0')  (' DUSP1_g%0'  ' RAF_f%0')  (' DUSP1_g%0'  ' mTORC1_c%0')  (' DUSP1_g%0'  ' RHEB%0')  (' DUSP1_g%0'  ' RTPK_g%0')  (' DUSP1_g%0'  ' PTEN%0')  (' DUSP1_g%0'  ' CASP3%0')  (' DUSP1_g%0'  ' PIK3CA%0')  (' DUSP1_g%0'  ' CREBBP%0')  (' DUSP1_g%0'  ' PTPN11%0')  (' DUSP1_g%0'  ' KRAS%0')  (' DUSP1_g%0'  ' MAP2K4%0')  (' DUSP1_g%0'  ' MAP2K7%0')  (' DUSP1_g%0'  ' MAPK14%0')  (' DUSP1_g%0'  ' JNK_f%0')  (' DUSP1_g%0'  ' MAP2K3%0')  (' DUSP1_g%0'  ' ERK_f%0')  (' DUSP1_g%0'  ' LIF%0')  (' DUSP1_g%0'  ' PPP1CA%0')  (' DUSP1_g%0'  ' GAB_f%0')  (' DUSP1_g%0'  ' SOS1%0')  (' DUSP1_g%0'  ' PRKCA%0')  (' DUSP1_g%0'  ' VAV1%0')  (' DUSP1_g%0'  ' PLCG1%0')  (' DUSP1_g%0'  ' PRKCD%0')  (' DUSP1_g%0'  ' RSK_f%0')  (' DUSP1_g%0'  ' S6K_f%0')  (' DUSP1_g%0'  ' PLK1%0')  (' DUSP1_g%0'  ' ILK%0')  (' DUSP1_g%0'  ' SOCS1%0')  (' DUSP1_g%0'  ' DUSP6%0')  (' DUSP1_g%0'  ' STAT3%0')  (' DUSP1_g%0'  ' LIMK2%0')  (' DUSP1_g%0'  ' EP300%0')  (' DUSP1_g%0'  ' STAT1%0')  (' DUSP1_g%0'  ' IKBKB%0')  (' DUSP1_g%0'  ' SRF%0')  (' DUSP1_g%0'  ' PIAS1%0')  (' DUSP1_g%0'  ' TRAF6%0')  (' DUSP1_g%0'  ' SOCS1_g%0')  (' DUSP1_g%0'  ' ISGF3_c%0')  (' DUSP1_g%0'  ' STAT2%0')  (' DUSP1_g%0'  ' CFLAR%0')  (' DUSP1_g%0'  ' SMAD2%0')  (' DUSP1_g%0'  ' MDM2_g%0')  (' DUSP1_g%0'  ' BAX%0')  (' DUSP1_g%0'  ' PRKACA%0')  (' DUSP1_g%0'  ' TGFB1%0')  (' DUSP1_g%0'  ' MAP3K8%0')  (' DUSP1_g%0'  ' TSC_f%0')  (' DUSP1_g%0'  ' SMAD4%0')  (' DUSP1_g%0'  ' BAD%0')  (' DUSP1_g%0'  ' MAP3K5%0')  (' DUSP1_g%0'  ' AKT1S1%0')  (' DUSP1_g%0'  ' SKI%0')  (' DUSP1_g%0'  ' SMAD3%0')  (' DUSP1_g%0'  ' MAPKAPK2%0')  (' DUSP1_g%0'  ' MSK_f%0')  (' DUSP1_g%0'  ' GRAP2%0')  (' DUSP1_g%0'  ' TAB_f%0')  (' DUSP1_g%0'  ' ATF2%0')  (' DUSP1_g%0'  ' SMAD5%0')  (' DUSP1_g%0'  ' SMAD1%0')  (' DUSP1_g%0'  ' FOS%0')  (' DUSP1_g%0'  ' JUN%0')  (' DUSP1_g%0'  ' MAP3K7%0')  (' DUSP1_g%0'  ' NLK%0')  (' DUSP1_g%0'  ' SMAD7_g%0')  (' DUSP1_g%0'  ' SMAD6_g%0')  (' DUSP1_g%0'  ' AP1_c%0')  (' DUSP1_g%0'  ' ACVR1%0')  (' DUSP1_g%0'  ' PTPN6%0')  (' DUSP1_g%0'  ' CDC42%0')  (' DUSP1_g%0'  ' GRB2%0')  (' DUSP1_g%0'  ' TGFBR1%0')  (' DUSP1_g%0'  ' SMURF1%0')  (' DUSP1_g%0'  ' SMURF2%0')  (' DUSP1_g%0'  ' RHOA%0')  (' DUSP1_g%0'  ' BMPR2%0')  (' DUSP1_g%0'  ' PARD6A%0')  (' DUSP1_g%0'  ' DAAM1%0')  (' DUSP1_g%0'  ' SFRP1_g%0')  (' DUSP1_g%0'  ' PPM1A%0')  (' DUSP1_g%0'  ' CFL_f%0')  (' DUSP1_g%0'  ' PAK1%0')  (' DUSP1_g%0'  ' MAP3K11%0')  (' DUSP1_g%0'  ' MAP3K4%0')  (' DUSP1_g%0'  ' LIMK1%0')  (' DUSP1_g%0'  ' ROCK1%0')  (' DUSP1_g%0'  ' ITCH%0')  (' DUSP1_g%0'  ' ARHGAP24%0')  (' DUSP1_g%0'  ' TIAM1%0')  (' DUSP1_g%0'  ' RND3%0')  (' DUSP1_g%0'  ' MAPK8IP3%0')  (' DUSP1_g%0'  ' MXD1%0')  (' DUSP1_g%0'  ' PIP3%0')  (' MSK_f%0'  ' SRC%0')  (' MSK_f%0'  ' CSK%0')  (' MSK_f%0'  ' CHUK%0')  (' MSK_f%0'  ' RAC_f%0')  (' MSK_f%0'  ' DUSP1%0')  (' MSK_f%0'  ' TGFBR2%0')  (' MSK_f%0'  ' ILR_f%0')  (' MSK_f%0'  ' SYK%0')  (' MSK_f%0'  ' IRAK1%0')  (' MSK_f%0'  ' SHC1%0')  (' MSK_f%0'  ' JAK_f%0')  (' MSK_f%0'  ' CBPp300_c%0')  (' MSK_f%0'  ' SKP2%0')  (' MSK_f%0'  ' TP53%0')  (' MSK_f%0'  ' SMAD7%0')  (' MSK_f%0'  ' SMAD6%0')  (' MSK_f%0'  ' DKK_f%0')  (' MSK_f%0'  ' FOXO_f%0')  (' MSK_f%0'  ' TCF7_f%0')  (' MSK_f%0'  ' DKK_g%0')  (' MSK_f%0'  ' MYC%0')  (' MSK_f%0'  ' CCND1%0')  (' MSK_f%0'  ' EGR1%0')  (' MSK_f%0'  ' MMP_f%0')  (' MSK_f%0'  ' PTEN_g%0')  (' MSK_f%0'  ' RTPK_f%0')  (' MSK_f%0'  ' CTNNB1%0')  (' MSK_f%0'  'LEF1%0')  (' MSK_f%0'  'SFRP1%0')  (' MSK_f%0'  'FZD_f%0')  (' MSK_f%0'  ' CASP8%0')  (' MSK_f%0'  ' REL_f%0')  (' MSK_f%0'  ' NFKB_f%0')  (' MSK_f%0'  ' DVL_f%0')  (' MSK_f%0'  ' LRP_f%0')  (' MSK_f%0'  ' BTRC%0')  (' MSK_f%0'  ' CK1_f%0')  (' MSK_f%0'  ' AXIN1%0')  (' MSK_f%0'  ' mTORC2_c%0')  (' MSK_f%0'  ' PDPK1%0')  (' MSK_f%0'  ' MEK_f%0')  (' MSK_f%0'  ' CYCS%0')  (' MSK_f%0'  ' CASP9%0')  (' MSK_f%0'  ' GSK3_f%0')  (' MSK_f%0'  ' IRS1%0')  (' MSK_f%0'  ' MDM2%0')  (' MSK_f%0'  ' AKT_f%0')  (' MSK_f%0'  ' BCL2%0')  (' MSK_f%0'  ' RAF_f%0')  (' MSK_f%0'  ' mTORC1_c%0')  (' MSK_f%0'  ' RHEB%0')  (' MSK_f%0'  ' RTPK_g%0')  (' MSK_f%0'  ' PTEN%0')  (' MSK_f%0'  ' CASP3%0')  (' MSK_f%0'  ' PIK3CA%0')  (' MSK_f%0'  ' CREBBP%0')  (' MSK_f%0'  ' PTPN11%0')  (' MSK_f%0'  ' KRAS%0')  (' MSK_f%0'  ' MAP2K4%0')  (' MSK_f%0'  ' MAP2K7%0')  (' MSK_f%0'  ' MAPK14%0')  (' MSK_f%0'  ' JNK_f%0')  (' MSK_f%0'  ' MAP2K3%0')  (' MSK_f%0'  ' ERK_f%0')  (' MSK_f%0'  ' LIF%0')  (' MSK_f%0'  ' PPP1CA%0')  (' MSK_f%0'  ' GAB_f%0')  (' MSK_f%0'  ' SOS1%0')  (' MSK_f%0'  ' PRKCA%0')  (' MSK_f%0'  ' VAV1%0')  (' MSK_f%0'  ' PLCG1%0')  (' MSK_f%0'  ' PRKCD%0')  (' MSK_f%0'  ' RSK_f%0')  (' MSK_f%0'  ' S6K_f%0')  (' MSK_f%0'  ' PLK1%0')  (' MSK_f%0'  ' ILK%0')  (' MSK_f%0'  ' SOCS1%0')  (' MSK_f%0'  ' DUSP6%0')  (' MSK_f%0'  ' STAT3%0')  (' MSK_f%0'  ' LIMK2%0')  (' MSK_f%0'  ' EP300%0')  (' MSK_f%0'  ' STAT1%0')  (' MSK_f%0'  ' IKBKB%0')  (' MSK_f%0'  ' SRF%0')  (' MSK_f%0'  ' PIAS1%0')  (' MSK_f%0'  ' TRAF6%0')  (' MSK_f%0'  ' SOCS1_g%0')  (' MSK_f%0'  ' ISGF3_c%0')  (' MSK_f%0'  ' STAT2%0')  (' MSK_f%0'  ' CFLAR%0')  (' MSK_f%0'  ' SMAD2%0')  (' MSK_f%0'  ' MDM2_g%0')  (' MSK_f%0'  ' BAX%0')  (' MSK_f%0'  ' PRKACA%0')  (' MSK_f%0'  ' TGFB1%0')  (' MSK_f%0'  ' MAP3K8%0')  (' MSK_f%0'  ' TSC_f%0')  (' MSK_f%0'  ' SMAD4%0')  (' MSK_f%0'  ' BAD%0')  (' MSK_f%0'  ' MAP3K5%0')  (' MSK_f%0'  ' AKT1S1%0')  (' MSK_f%0'  ' SKI%0')  (' MSK_f%0'  ' SMAD3%0')  (' MSK_f%0'  ' MAPKAPK2%0')  (' MSK_f%0'  ' DUSP1_g%0')  (' MSK_f%0'  ' GRAP2%0')  (' MSK_f%0'  ' TAB_f%0')  (' MSK_f%0'  ' ATF2%0')  (' MSK_f%0'  ' SMAD5%0')  (' MSK_f%0'  ' SMAD1%0')  (' MSK_f%0'  ' FOS%0')  (' MSK_f%0'  ' JUN%0')  (' MSK_f%0'  ' MAP3K7%0')  (' MSK_f%0'  ' NLK%0')  (' MSK_f%0'  ' SMAD7_g%0')  (' MSK_f%0'  ' SMAD6_g%0')  (' MSK_f%0'  ' AP1_c%0')  (' MSK_f%0'  ' ACVR1%0')  (' MSK_f%0'  ' PTPN6%0')  (' MSK_f%0'  ' CDC42%0')  (' MSK_f%0'  ' GRB2%0')  (' MSK_f%0'  ' TGFBR1%0')  (' MSK_f%0'  ' SMURF1%0')  (' MSK_f%0'  ' SMURF2%0')  (' MSK_f%0'  ' RHOA%0')  (' MSK_f%0'  ' BMPR2%0')  (' MSK_f%0'  ' PARD6A%0')  (' MSK_f%0'  ' DAAM1%0')  (' MSK_f%0'  ' SFRP1_g%0')  (' MSK_f%0'  ' PPM1A%0')  (' MSK_f%0'  ' CFL_f%0')  (' MSK_f%0'  ' PAK1%0')  (' MSK_f%0'  ' MAP3K11%0')  (' MSK_f%0'  ' MAP3K4%0')  (' MSK_f%0'  ' LIMK1%0')  (' MSK_f%0'  ' ROCK1%0')  (' MSK_f%0'  ' ITCH%0')  (' MSK_f%0'  ' ARHGAP24%0')  (' MSK_f%0'  ' TIAM1%0')  (' MSK_f%0'  ' RND3%0')  (' MSK_f%0'  ' MAPK8IP3%0')  (' MSK_f%0'  ' MXD1%0')  (' MSK_f%0'  ' PIP3%0')  (' GRAP2%0'  ' SRC%0')  (' GRAP2%0'  ' CSK%0')  (' GRAP2%0'  ' CHUK%0')  (' GRAP2%0'  ' RAC_f%0')  (' GRAP2%0'  ' DUSP1%0')  (' GRAP2%0'  ' TGFBR2%0')  (' GRAP2%0'  ' ILR_f%0')  (' GRAP2%0'  ' SYK%0')  (' GRAP2%0'  ' IRAK1%0')  (' GRAP2%0'  ' SHC1%0')  (' GRAP2%0'  ' JAK_f%0')  (' GRAP2%0'  ' CBPp300_c%0')  (' GRAP2%0'  ' SKP2%0')  (' GRAP2%0'  ' TP53%0')  (' GRAP2%0'  ' SMAD7%0')  (' GRAP2%0'  ' SMAD6%0')  (' GRAP2%0'  ' DKK_f%0')  (' GRAP2%0'  ' FOXO_f%0')  (' GRAP2%0'  ' TCF7_f%0')  (' GRAP2%0'  ' DKK_g%0')  (' GRAP2%0'  ' MYC%0')  (' GRAP2%0'  ' CCND1%0')  (' GRAP2%0'  ' EGR1%0')  (' GRAP2%0'  ' MMP_f%0')  (' GRAP2%0'  ' PTEN_g%0')  (' GRAP2%0'  ' RTPK_f%0')  (' GRAP2%0'  ' CTNNB1%0')  (' GRAP2%0'  'LEF1%0')  (' GRAP2%0'  'SFRP1%0')  (' GRAP2%0'  'FZD_f%0')  (' GRAP2%0'  ' CASP8%0')  (' GRAP2%0'  ' REL_f%0')  (' GRAP2%0'  ' NFKB_f%0')  (' GRAP2%0'  ' DVL_f%0')  (' GRAP2%0'  ' LRP_f%0')  (' GRAP2%0'  ' BTRC%0')  (' GRAP2%0'  ' CK1_f%0')  (' GRAP2%0'  ' AXIN1%0')  (' GRAP2%0'  ' mTORC2_c%0')  (' GRAP2%0'  ' PDPK1%0')  (' GRAP2%0'  ' MEK_f%0')  (' GRAP2%0'  ' CYCS%0')  (' GRAP2%0'  ' CASP9%0')  (' GRAP2%0'  ' GSK3_f%0')  (' GRAP2%0'  ' IRS1%0')  (' GRAP2%0'  ' MDM2%0')  (' GRAP2%0'  ' AKT_f%0')  (' GRAP2%0'  ' BCL2%0')  (' GRAP2%0'  ' RAF_f%0')  (' GRAP2%0'  ' mTORC1_c%0')  (' GRAP2%0'  ' RHEB%0')  (' GRAP2%0'  ' RTPK_g%0')  (' GRAP2%0'  ' PTEN%0')  (' GRAP2%0'  ' CASP3%0')  (' GRAP2%0'  ' PIK3CA%0')  (' GRAP2%0'  ' CREBBP%0')  (' GRAP2%0'  ' PTPN11%0')  (' GRAP2%0'  ' KRAS%0')  (' GRAP2%0'  ' MAP2K4%0')  (' GRAP2%0'  ' MAP2K7%0')  (' GRAP2%0'  ' MAPK14%0')  (' GRAP2%0'  ' JNK_f%0')  (' GRAP2%0'  ' MAP2K3%0')  (' GRAP2%0'  ' ERK_f%0')  (' GRAP2%0'  ' LIF%0')  (' GRAP2%0'  ' PPP1CA%0')  (' GRAP2%0'  ' GAB_f%0')  (' GRAP2%0'  ' SOS1%0')  (' GRAP2%0'  ' PRKCA%0')  (' GRAP2%0'  ' VAV1%0')  (' GRAP2%0'  ' PLCG1%0')  (' GRAP2%0'  ' PRKCD%0')  (' GRAP2%0'  ' RSK_f%0')  (' GRAP2%0'  ' S6K_f%0')  (' GRAP2%0'  ' PLK1%0')  (' GRAP2%0'  ' ILK%0')  (' GRAP2%0'  ' SOCS1%0')  (' GRAP2%0'  ' DUSP6%0')  (' GRAP2%0'  ' STAT3%0')  (' GRAP2%0'  ' LIMK2%0')  (' GRAP2%0'  ' EP300%0')  (' GRAP2%0'  ' STAT1%0')  (' GRAP2%0'  ' IKBKB%0')  (' GRAP2%0'  ' SRF%0')  (' GRAP2%0'  ' PIAS1%0')  (' GRAP2%0'  ' TRAF6%0')  (' GRAP2%0'  ' SOCS1_g%0')  (' GRAP2%0'  ' ISGF3_c%0')  (' GRAP2%0'  ' STAT2%0')  (' GRAP2%0'  ' CFLAR%0')  (' GRAP2%0'  ' SMAD2%0')  (' GRAP2%0'  ' MDM2_g%0')  (' GRAP2%0'  ' BAX%0')  (' GRAP2%0'  ' PRKACA%0')  (' GRAP2%0'  ' TGFB1%0')  (' GRAP2%0'  ' MAP3K8%0')  (' GRAP2%0'  ' TSC_f%0')  (' GRAP2%0'  ' SMAD4%0')  (' GRAP2%0'  ' BAD%0')  (' GRAP2%0'  ' MAP3K5%0')  (' GRAP2%0'  ' AKT1S1%0')  (' GRAP2%0'  ' SKI%0')  (' GRAP2%0'  ' SMAD3%0')  (' GRAP2%0'  ' MAPKAPK2%0')  (' GRAP2%0'  ' DUSP1_g%0')  (' GRAP2%0'  ' MSK_f%0')  (' GRAP2%0'  ' TAB_f%0')  (' GRAP2%0'  ' ATF2%0')  (' GRAP2%0'  ' SMAD5%0')  (' GRAP2%0'  ' SMAD1%0')  (' GRAP2%0'  ' FOS%0')  (' GRAP2%0'  ' JUN%0')  (' GRAP2%0'  ' MAP3K7%0')  (' GRAP2%0'  ' NLK%0')  (' GRAP2%0'  ' SMAD7_g%0')  (' GRAP2%0'  ' SMAD6_g%0')  (' GRAP2%0'  ' AP1_c%0')  (' GRAP2%0'  ' ACVR1%0')  (' GRAP2%0'  ' PTPN6%0')  (' GRAP2%0'  ' CDC42%0')  (' GRAP2%0'  ' GRB2%0')  (' GRAP2%0'  ' TGFBR1%0')  (' GRAP2%0'  ' SMURF1%0')  (' GRAP2%0'  ' SMURF2%0')  (' GRAP2%0'  ' RHOA%0')  (' GRAP2%0'  ' BMPR2%0')  (' GRAP2%0'  ' PARD6A%0')  (' GRAP2%0'  ' DAAM1%0')  (' GRAP2%0'  ' SFRP1_g%0')  (' GRAP2%0'  ' PPM1A%0')  (' GRAP2%0'  ' CFL_f%0')  (' GRAP2%0'  ' PAK1%0')  (' GRAP2%0'  ' MAP3K11%0')  (' GRAP2%0'  ' MAP3K4%0')  (' GRAP2%0'  ' LIMK1%0')  (' GRAP2%0'  ' ROCK1%0')  (' GRAP2%0'  ' ITCH%0')  (' GRAP2%0'  ' ARHGAP24%0')  (' GRAP2%0'  ' TIAM1%0')  (' GRAP2%0'  ' RND3%0')  (' GRAP2%0'  ' MAPK8IP3%0')  (' GRAP2%0'  ' MXD1%0')  (' GRAP2%0'  ' PIP3%0')  (' TAB_f%0'  ' SRC%0')  (' TAB_f%0'  ' CSK%0')  (' TAB_f%0'  ' CHUK%0')  (' TAB_f%0'  ' RAC_f%0')  (' TAB_f%0'  ' DUSP1%0')  (' TAB_f%0'  ' TGFBR2%0')  (' TAB_f%0'  ' ILR_f%0')  (' TAB_f%0'  ' SYK%0')  (' TAB_f%0'  ' IRAK1%0')  (' TAB_f%0'  ' SHC1%0')  (' TAB_f%0'  ' JAK_f%0')  (' TAB_f%0'  ' CBPp300_c%0')  (' TAB_f%0'  ' SKP2%0')  (' TAB_f%0'  ' TP53%0')  (' TAB_f%0'  ' SMAD7%0')  (' TAB_f%0'  ' SMAD6%0')  (' TAB_f%0'  ' DKK_f%0')  (' TAB_f%0'  ' FOXO_f%0')  (' TAB_f%0'  ' TCF7_f%0')  (' TAB_f%0'  ' DKK_g%0')  (' TAB_f%0'  ' MYC%0')  (' TAB_f%0'  ' CCND1%0')  (' TAB_f%0'  ' EGR1%0')  (' TAB_f%0'  ' MMP_f%0')  (' TAB_f%0'  ' PTEN_g%0')  (' TAB_f%0'  ' RTPK_f%0')  (' TAB_f%0'  ' CTNNB1%0')  (' TAB_f%0'  'LEF1%0')  (' TAB_f%0'  'SFRP1%0')  (' TAB_f%0'  'FZD_f%0')  (' TAB_f%0'  ' CASP8%0')  (' TAB_f%0'  ' REL_f%0')  (' TAB_f%0'  ' NFKB_f%0')  (' TAB_f%0'  ' DVL_f%0')  (' TAB_f%0'  ' LRP_f%0')  (' TAB_f%0'  ' BTRC%0')  (' TAB_f%0'  ' CK1_f%0')  (' TAB_f%0'  ' AXIN1%0')  (' TAB_f%0'  ' mTORC2_c%0')  (' TAB_f%0'  ' PDPK1%0')  (' TAB_f%0'  ' MEK_f%0')  (' TAB_f%0'  ' CYCS%0')  (' TAB_f%0'  ' CASP9%0')  (' TAB_f%0'  ' GSK3_f%0')  (' TAB_f%0'  ' IRS1%0')  (' TAB_f%0'  ' MDM2%0')  (' TAB_f%0'  ' AKT_f%0')  (' TAB_f%0'  ' BCL2%0')  (' TAB_f%0'  ' RAF_f%0')  (' TAB_f%0'  ' mTORC1_c%0')  (' TAB_f%0'  ' RHEB%0')  (' TAB_f%0'  ' RTPK_g%0')  (' TAB_f%0'  ' PTEN%0')  (' TAB_f%0'  ' CASP3%0')  (' TAB_f%0'  ' PIK3CA%0')  (' TAB_f%0'  ' CREBBP%0')  (' TAB_f%0'  ' PTPN11%0')  (' TAB_f%0'  ' KRAS%0')  (' TAB_f%0'  ' MAP2K4%0')  (' TAB_f%0'  ' MAP2K7%0')  (' TAB_f%0'  ' MAPK14%0')  (' TAB_f%0'  ' JNK_f%0')  (' TAB_f%0'  ' MAP2K3%0')  (' TAB_f%0'  ' ERK_f%0')  (' TAB_f%0'  ' LIF%0')  (' TAB_f%0'  ' PPP1CA%0')  (' TAB_f%0'  ' GAB_f%0')  (' TAB_f%0'  ' SOS1%0')  (' TAB_f%0'  ' PRKCA%0')  (' TAB_f%0'  ' VAV1%0')  (' TAB_f%0'  ' PLCG1%0')  (' TAB_f%0'  ' PRKCD%0')  (' TAB_f%0'  ' RSK_f%0')  (' TAB_f%0'  ' S6K_f%0')  (' TAB_f%0'  ' PLK1%0')  (' TAB_f%0'  ' ILK%0')  (' TAB_f%0'  ' SOCS1%0')  (' TAB_f%0'  ' DUSP6%0')  (' TAB_f%0'  ' STAT3%0')  (' TAB_f%0'  ' LIMK2%0')  (' TAB_f%0'  ' EP300%0')  (' TAB_f%0'  ' STAT1%0')  (' TAB_f%0'  ' IKBKB%0')  (' TAB_f%0'  ' SRF%0')  (' TAB_f%0'  ' PIAS1%0')  (' TAB_f%0'  ' TRAF6%0')  (' TAB_f%0'  ' SOCS1_g%0')  (' TAB_f%0'  ' ISGF3_c%0')  (' TAB_f%0'  ' STAT2%0')  (' TAB_f%0'  ' CFLAR%0')  (' TAB_f%0'  ' SMAD2%0')  (' TAB_f%0'  ' MDM2_g%0')  (' TAB_f%0'  ' BAX%0')  (' TAB_f%0'  ' PRKACA%0')  (' TAB_f%0'  ' TGFB1%0')  (' TAB_f%0'  ' MAP3K8%0')  (' TAB_f%0'  ' TSC_f%0')  (' TAB_f%0'  ' SMAD4%0')  (' TAB_f%0'  ' BAD%0')  (' TAB_f%0'  ' MAP3K5%0')  (' TAB_f%0'  ' AKT1S1%0')  (' TAB_f%0'  ' SKI%0')  (' TAB_f%0'  ' SMAD3%0')  (' TAB_f%0'  ' MAPKAPK2%0')  (' TAB_f%0'  ' DUSP1_g%0')  (' TAB_f%0'  ' MSK_f%0')  (' TAB_f%0'  ' GRAP2%0')  (' TAB_f%0'  ' ATF2%0')  (' TAB_f%0'  ' SMAD5%0')  (' TAB_f%0'  ' SMAD1%0')  (' TAB_f%0'  ' FOS%0')  (' TAB_f%0'  ' JUN%0')  (' TAB_f%0'  ' MAP3K7%0')  (' TAB_f%0'  ' NLK%0')  (' TAB_f%0'  ' SMAD7_g%0')  (' TAB_f%0'  ' SMAD6_g%0')  (' TAB_f%0'  ' AP1_c%0')  (' TAB_f%0'  ' ACVR1%0')  (' TAB_f%0'  ' PTPN6%0')  (' TAB_f%0'  ' CDC42%0')  (' TAB_f%0'  ' GRB2%0')  (' TAB_f%0'  ' TGFBR1%0')  (' TAB_f%0'  ' SMURF1%0')  (' TAB_f%0'  ' SMURF2%0')  (' TAB_f%0'  ' RHOA%0')  (' TAB_f%0'  ' BMPR2%0')  (' TAB_f%0'  ' PARD6A%0')  (' TAB_f%0'  ' DAAM1%0')  (' TAB_f%0'  ' SFRP1_g%0')  (' TAB_f%0'  ' PPM1A%0')  (' TAB_f%0'  ' CFL_f%0')  (' TAB_f%0'  ' PAK1%0')  (' TAB_f%0'  ' MAP3K11%0')  (' TAB_f%0'  ' MAP3K4%0')  (' TAB_f%0'  ' LIMK1%0')  (' TAB_f%0'  ' ROCK1%0')  (' TAB_f%0'  ' ITCH%0')  (' TAB_f%0'  ' ARHGAP24%0')  (' TAB_f%0'  ' TIAM1%0')  (' TAB_f%0'  ' RND3%0')  (' TAB_f%0'  ' MAPK8IP3%0')  (' TAB_f%0'  ' MXD1%0')  (' TAB_f%0'  ' PIP3%0')  (' ATF2%0'  ' SRC%0')  (' ATF2%0'  ' CSK%0')  (' ATF2%0'  ' CHUK%0')  (' ATF2%0'  ' RAC_f%0')  (' ATF2%0'  ' DUSP1%0')  (' ATF2%0'  ' TGFBR2%0')  (' ATF2%0'  ' ILR_f%0')  (' ATF2%0'  ' SYK%0')  (' ATF2%0'  ' IRAK1%0')  (' ATF2%0'  ' SHC1%0')  (' ATF2%0'  ' JAK_f%0')  (' ATF2%0'  ' CBPp300_c%0')  (' ATF2%0'  ' SKP2%0')  (' ATF2%0'  ' TP53%0')  (' ATF2%0'  ' SMAD7%0')  (' ATF2%0'  ' SMAD6%0')  (' ATF2%0'  ' DKK_f%0')  (' ATF2%0'  ' FOXO_f%0')  (' ATF2%0'  ' TCF7_f%0')  (' ATF2%0'  ' DKK_g%0')  (' ATF2%0'  ' MYC%0')  (' ATF2%0'  ' CCND1%0')  (' ATF2%0'  ' EGR1%0')  (' ATF2%0'  ' MMP_f%0')  (' ATF2%0'  ' PTEN_g%0')  (' ATF2%0'  ' RTPK_f%0')  (' ATF2%0'  ' CTNNB1%0')  (' ATF2%0'  'LEF1%0')  (' ATF2%0'  'SFRP1%0')  (' ATF2%0'  'FZD_f%0')  (' ATF2%0'  ' CASP8%0')  (' ATF2%0'  ' REL_f%0')  (' ATF2%0'  ' NFKB_f%0')  (' ATF2%0'  ' DVL_f%0')  (' ATF2%0'  ' LRP_f%0')  (' ATF2%0'  ' BTRC%0')  (' ATF2%0'  ' CK1_f%0')  (' ATF2%0'  ' AXIN1%0')  (' ATF2%0'  ' mTORC2_c%0')  (' ATF2%0'  ' PDPK1%0')  (' ATF2%0'  ' MEK_f%0')  (' ATF2%0'  ' CYCS%0')  (' ATF2%0'  ' CASP9%0')  (' ATF2%0'  ' GSK3_f%0')  (' ATF2%0'  ' IRS1%0')  (' ATF2%0'  ' MDM2%0')  (' ATF2%0'  ' AKT_f%0')  (' ATF2%0'  ' BCL2%0')  (' ATF2%0'  ' RAF_f%0')  (' ATF2%0'  ' mTORC1_c%0')  (' ATF2%0'  ' RHEB%0')  (' ATF2%0'  ' RTPK_g%0')  (' ATF2%0'  ' PTEN%0')  (' ATF2%0'  ' CASP3%0')  (' ATF2%0'  ' PIK3CA%0')  (' ATF2%0'  ' CREBBP%0')  (' ATF2%0'  ' PTPN11%0')  (' ATF2%0'  ' KRAS%0')  (' ATF2%0'  ' MAP2K4%0')  (' ATF2%0'  ' MAP2K7%0')  (' ATF2%0'  ' MAPK14%0')  (' ATF2%0'  ' JNK_f%0')  (' ATF2%0'  ' MAP2K3%0')  (' ATF2%0'  ' ERK_f%0')  (' ATF2%0'  ' LIF%0')  (' ATF2%0'  ' PPP1CA%0')  (' ATF2%0'  ' GAB_f%0')  (' ATF2%0'  ' SOS1%0')  (' ATF2%0'  ' PRKCA%0')  (' ATF2%0'  ' VAV1%0')  (' ATF2%0'  ' PLCG1%0')  (' ATF2%0'  ' PRKCD%0')  (' ATF2%0'  ' RSK_f%0')  (' ATF2%0'  ' S6K_f%0')  (' ATF2%0'  ' PLK1%0')  (' ATF2%0'  ' ILK%0')  (' ATF2%0'  ' SOCS1%0')  (' ATF2%0'  ' DUSP6%0')  (' ATF2%0'  ' STAT3%0')  (' ATF2%0'  ' LIMK2%0')  (' ATF2%0'  ' EP300%0')  (' ATF2%0'  ' STAT1%0')  (' ATF2%0'  ' IKBKB%0')  (' ATF2%0'  ' SRF%0')  (' ATF2%0'  ' PIAS1%0')  (' ATF2%0'  ' TRAF6%0')  (' ATF2%0'  ' SOCS1_g%0')  (' ATF2%0'  ' ISGF3_c%0')  (' ATF2%0'  ' STAT2%0')  (' ATF2%0'  ' CFLAR%0')  (' ATF2%0'  ' SMAD2%0')  (' ATF2%0'  ' MDM2_g%0')  (' ATF2%0'  ' BAX%0')  (' ATF2%0'  ' PRKACA%0')  (' ATF2%0'  ' TGFB1%0')  (' ATF2%0'  ' MAP3K8%0')  (' ATF2%0'  ' TSC_f%0')  (' ATF2%0'  ' SMAD4%0')  (' ATF2%0'  ' BAD%0')  (' ATF2%0'  ' MAP3K5%0')  (' ATF2%0'  ' AKT1S1%0')  (' ATF2%0'  ' SKI%0')  (' ATF2%0'  ' SMAD3%0')  (' ATF2%0'  ' MAPKAPK2%0')  (' ATF2%0'  ' DUSP1_g%0')  (' ATF2%0'  ' MSK_f%0')  (' ATF2%0'  ' GRAP2%0')  (' ATF2%0'  ' TAB_f%0')  (' ATF2%0'  ' SMAD5%0')  (' ATF2%0'  ' SMAD1%0')  (' ATF2%0'  ' FOS%0')  (' ATF2%0'  ' JUN%0')  (' ATF2%0'  ' MAP3K7%0')  (' ATF2%0'  ' NLK%0')  (' ATF2%0'  ' SMAD7_g%0')  (' ATF2%0'  ' SMAD6_g%0')  (' ATF2%0'  ' AP1_c%0')  (' ATF2%0'  ' ACVR1%0')  (' ATF2%0'  ' PTPN6%0')  (' ATF2%0'  ' CDC42%0')  (' ATF2%0'  ' GRB2%0')  (' ATF2%0'  ' TGFBR1%0')  (' ATF2%0'  ' SMURF1%0')  (' ATF2%0'  ' SMURF2%0')  (' ATF2%0'  ' RHOA%0')  (' ATF2%0'  ' BMPR2%0')  (' ATF2%0'  ' PARD6A%0')  (' ATF2%0'  ' DAAM1%0')  (' ATF2%0'  ' SFRP1_g%0')  (' ATF2%0'  ' PPM1A%0')  (' ATF2%0'  ' CFL_f%0')  (' ATF2%0'  ' PAK1%0')  (' ATF2%0'  ' MAP3K11%0')  (' ATF2%0'  ' MAP3K4%0')  (' ATF2%0'  ' LIMK1%0')  (' ATF2%0'  ' ROCK1%0')  (' ATF2%0'  ' ITCH%0')  (' ATF2%0'  ' ARHGAP24%0')  (' ATF2%0'  ' TIAM1%0')  (' ATF2%0'  ' RND3%0')  (' ATF2%0'  ' MAPK8IP3%0')  (' ATF2%0'  ' MXD1%0')  (' ATF2%0'  ' PIP3%0')  (' SMAD5%0'  ' SRC%0')  (' SMAD5%0'  ' CSK%0')  (' SMAD5%0'  ' CHUK%0')  (' SMAD5%0'  ' RAC_f%0')  (' SMAD5%0'  ' DUSP1%0')  (' SMAD5%0'  ' TGFBR2%0')  (' SMAD5%0'  ' ILR_f%0')  (' SMAD5%0'  ' SYK%0')  (' SMAD5%0'  ' IRAK1%0')  (' SMAD5%0'  ' SHC1%0')  (' SMAD5%0'  ' JAK_f%0')  (' SMAD5%0'  ' CBPp300_c%0')  (' SMAD5%0'  ' SKP2%0')  (' SMAD5%0'  ' TP53%0')  (' SMAD5%0'  ' SMAD7%0')  (' SMAD5%0'  ' SMAD6%0')  (' SMAD5%0'  ' DKK_f%0')  (' SMAD5%0'  ' FOXO_f%0')  (' SMAD5%0'  ' TCF7_f%0')  (' SMAD5%0'  ' DKK_g%0')  (' SMAD5%0'  ' MYC%0')  (' SMAD5%0'  ' CCND1%0')  (' SMAD5%0'  ' EGR1%0')  (' SMAD5%0'  ' MMP_f%0')  (' SMAD5%0'  ' PTEN_g%0')  (' SMAD5%0'  ' RTPK_f%0')  (' SMAD5%0'  ' CTNNB1%0')  (' SMAD5%0'  'LEF1%0')  (' SMAD5%0'  'SFRP1%0')  (' SMAD5%0'  'FZD_f%0')  (' SMAD5%0'  ' CASP8%0')  (' SMAD5%0'  ' REL_f%0')  (' SMAD5%0'  ' NFKB_f%0')  (' SMAD5%0'  ' DVL_f%0')  (' SMAD5%0'  ' LRP_f%0')  (' SMAD5%0'  ' BTRC%0')  (' SMAD5%0'  ' CK1_f%0')  (' SMAD5%0'  ' AXIN1%0')  (' SMAD5%0'  ' mTORC2_c%0')  (' SMAD5%0'  ' PDPK1%0')  (' SMAD5%0'  ' MEK_f%0')  (' SMAD5%0'  ' CYCS%0')  (' SMAD5%0'  ' CASP9%0')  (' SMAD5%0'  ' GSK3_f%0')  (' SMAD5%0'  ' IRS1%0')  (' SMAD5%0'  ' MDM2%0')  (' SMAD5%0'  ' AKT_f%0')  (' SMAD5%0'  ' BCL2%0')  (' SMAD5%0'  ' RAF_f%0')  (' SMAD5%0'  ' mTORC1_c%0')  (' SMAD5%0'  ' RHEB%0')  (' SMAD5%0'  ' RTPK_g%0')  (' SMAD5%0'  ' PTEN%0')  (' SMAD5%0'  ' CASP3%0')  (' SMAD5%0'  ' PIK3CA%0')  (' SMAD5%0'  ' CREBBP%0')  (' SMAD5%0'  ' PTPN11%0')  (' SMAD5%0'  ' KRAS%0')  (' SMAD5%0'  ' MAP2K4%0')  (' SMAD5%0'  ' MAP2K7%0')  (' SMAD5%0'  ' MAPK14%0')  (' SMAD5%0'  ' JNK_f%0')  (' SMAD5%0'  ' MAP2K3%0')  (' SMAD5%0'  ' ERK_f%0')  (' SMAD5%0'  ' LIF%0')  (' SMAD5%0'  ' PPP1CA%0')  (' SMAD5%0'  ' GAB_f%0')  (' SMAD5%0'  ' SOS1%0')  (' SMAD5%0'  ' PRKCA%0')  (' SMAD5%0'  ' VAV1%0')  (' SMAD5%0'  ' PLCG1%0')  (' SMAD5%0'  ' PRKCD%0')  (' SMAD5%0'  ' RSK_f%0')  (' SMAD5%0'  ' S6K_f%0')  (' SMAD5%0'  ' PLK1%0')  (' SMAD5%0'  ' ILK%0')  (' SMAD5%0'  ' SOCS1%0')  (' SMAD5%0'  ' DUSP6%0')  (' SMAD5%0'  ' STAT3%0')  (' SMAD5%0'  ' LIMK2%0')  (' SMAD5%0'  ' EP300%0')  (' SMAD5%0'  ' STAT1%0')  (' SMAD5%0'  ' IKBKB%0')  (' SMAD5%0'  ' SRF%0')  (' SMAD5%0'  ' PIAS1%0')  (' SMAD5%0'  ' TRAF6%0')  (' SMAD5%0'  ' SOCS1_g%0')  (' SMAD5%0'  ' ISGF3_c%0')  (' SMAD5%0'  ' STAT2%0')  (' SMAD5%0'  ' CFLAR%0')  (' SMAD5%0'  ' SMAD2%0')  (' SMAD5%0'  ' MDM2_g%0')  (' SMAD5%0'  ' BAX%0')  (' SMAD5%0'  ' PRKACA%0')  (' SMAD5%0'  ' TGFB1%0')  (' SMAD5%0'  ' MAP3K8%0')  (' SMAD5%0'  ' TSC_f%0')  (' SMAD5%0'  ' SMAD4%0')  (' SMAD5%0'  ' BAD%0')  (' SMAD5%0'  ' MAP3K5%0')  (' SMAD5%0'  ' AKT1S1%0')  (' SMAD5%0'  ' SKI%0')  (' SMAD5%0'  ' SMAD3%0')  (' SMAD5%0'  ' MAPKAPK2%0')  (' SMAD5%0'  ' DUSP1_g%0')  (' SMAD5%0'  ' MSK_f%0')  (' SMAD5%0'  ' GRAP2%0')  (' SMAD5%0'  ' TAB_f%0')  (' SMAD5%0'  ' ATF2%0')  (' SMAD5%0'  ' SMAD1%0')  (' SMAD5%0'  ' FOS%0')  (' SMAD5%0'  ' JUN%0')  (' SMAD5%0'  ' MAP3K7%0')  (' SMAD5%0'  ' NLK%0')  (' SMAD5%0'  ' SMAD7_g%0')  (' SMAD5%0'  ' SMAD6_g%0')  (' SMAD5%0'  ' AP1_c%0')  (' SMAD5%0'  ' ACVR1%0')  (' SMAD5%0'  ' PTPN6%0')  (' SMAD5%0'  ' CDC42%0')  (' SMAD5%0'  ' GRB2%0')  (' SMAD5%0'  ' TGFBR1%0')  (' SMAD5%0'  ' SMURF1%0')  (' SMAD5%0'  ' SMURF2%0')  (' SMAD5%0'  ' RHOA%0')  (' SMAD5%0'  ' BMPR2%0')  (' SMAD5%0'  ' PARD6A%0')  (' SMAD5%0'  ' DAAM1%0')  (' SMAD5%0'  ' SFRP1_g%0')  (' SMAD5%0'  ' PPM1A%0')  (' SMAD5%0'  ' CFL_f%0')  (' SMAD5%0'  ' PAK1%0')  (' SMAD5%0'  ' MAP3K11%0')  (' SMAD5%0'  ' MAP3K4%0')  (' SMAD5%0'  ' LIMK1%0')  (' SMAD5%0'  ' ROCK1%0')  (' SMAD5%0'  ' ITCH%0')  (' SMAD5%0'  ' ARHGAP24%0')  (' SMAD5%0'  ' TIAM1%0')  (' SMAD5%0'  ' RND3%0')  (' SMAD5%0'  ' MAPK8IP3%0')  (' SMAD5%0'  ' MXD1%0')  (' SMAD5%0'  ' PIP3%0')  (' SMAD1%0'  ' SRC%0')  (' SMAD1%0'  ' CSK%0')  (' SMAD1%0'  ' CHUK%0')  (' SMAD1%0'  ' RAC_f%0')  (' SMAD1%0'  ' DUSP1%0')  (' SMAD1%0'  ' TGFBR2%0')  (' SMAD1%0'  ' ILR_f%0')  (' SMAD1%0'  ' SYK%0')  (' SMAD1%0'  ' IRAK1%0')  (' SMAD1%0'  ' SHC1%0')  (' SMAD1%0'  ' JAK_f%0')  (' SMAD1%0'  ' CBPp300_c%0')  (' SMAD1%0'  ' SKP2%0')  (' SMAD1%0'  ' TP53%0')  (' SMAD1%0'  ' SMAD7%0')  (' SMAD1%0'  ' SMAD6%0')  (' SMAD1%0'  ' DKK_f%0')  (' SMAD1%0'  ' FOXO_f%0')  (' SMAD1%0'  ' TCF7_f%0')  (' SMAD1%0'  ' DKK_g%0')  (' SMAD1%0'  ' MYC%0')  (' SMAD1%0'  ' CCND1%0')  (' SMAD1%0'  ' EGR1%0')  (' SMAD1%0'  ' MMP_f%0')  (' SMAD1%0'  ' PTEN_g%0')  (' SMAD1%0'  ' RTPK_f%0')  (' SMAD1%0'  ' CTNNB1%0')  (' SMAD1%0'  'LEF1%0')  (' SMAD1%0'  'SFRP1%0')  (' SMAD1%0'  'FZD_f%0')  (' SMAD1%0'  ' CASP8%0')  (' SMAD1%0'  ' REL_f%0')  (' SMAD1%0'  ' NFKB_f%0')  (' SMAD1%0'  ' DVL_f%0')  (' SMAD1%0'  ' LRP_f%0')  (' SMAD1%0'  ' BTRC%0')  (' SMAD1%0'  ' CK1_f%0')  (' SMAD1%0'  ' AXIN1%0')  (' SMAD1%0'  ' mTORC2_c%0')  (' SMAD1%0'  ' PDPK1%0')  (' SMAD1%0'  ' MEK_f%0')  (' SMAD1%0'  ' CYCS%0')  (' SMAD1%0'  ' CASP9%0')  (' SMAD1%0'  ' GSK3_f%0')  (' SMAD1%0'  ' IRS1%0')  (' SMAD1%0'  ' MDM2%0')  (' SMAD1%0'  ' AKT_f%0')  (' SMAD1%0'  ' BCL2%0')  (' SMAD1%0'  ' RAF_f%0')  (' SMAD1%0'  ' mTORC1_c%0')  (' SMAD1%0'  ' RHEB%0')  (' SMAD1%0'  ' RTPK_g%0')  (' SMAD1%0'  ' PTEN%0')  (' SMAD1%0'  ' CASP3%0')  (' SMAD1%0'  ' PIK3CA%0')  (' SMAD1%0'  ' CREBBP%0')  (' SMAD1%0'  ' PTPN11%0')  (' SMAD1%0'  ' KRAS%0')  (' SMAD1%0'  ' MAP2K4%0')  (' SMAD1%0'  ' MAP2K7%0')  (' SMAD1%0'  ' MAPK14%0')  (' SMAD1%0'  ' JNK_f%0')  (' SMAD1%0'  ' MAP2K3%0')  (' SMAD1%0'  ' ERK_f%0')  (' SMAD1%0'  ' LIF%0')  (' SMAD1%0'  ' PPP1CA%0')  (' SMAD1%0'  ' GAB_f%0')  (' SMAD1%0'  ' SOS1%0')  (' SMAD1%0'  ' PRKCA%0')  (' SMAD1%0'  ' VAV1%0')  (' SMAD1%0'  ' PLCG1%0')  (' SMAD1%0'  ' PRKCD%0')  (' SMAD1%0'  ' RSK_f%0')  (' SMAD1%0'  ' S6K_f%0')  (' SMAD1%0'  ' PLK1%0')  (' SMAD1%0'  ' ILK%0')  (' SMAD1%0'  ' SOCS1%0')  (' SMAD1%0'  ' DUSP6%0')  (' SMAD1%0'  ' STAT3%0')  (' SMAD1%0'  ' LIMK2%0')  (' SMAD1%0'  ' EP300%0')  (' SMAD1%0'  ' STAT1%0')  (' SMAD1%0'  ' IKBKB%0')  (' SMAD1%0'  ' SRF%0')  (' SMAD1%0'  ' PIAS1%0')  (' SMAD1%0'  ' TRAF6%0')  (' SMAD1%0'  ' SOCS1_g%0')  (' SMAD1%0'  ' ISGF3_c%0')  (' SMAD1%0'  ' STAT2%0')  (' SMAD1%0'  ' CFLAR%0')  (' SMAD1%0'  ' SMAD2%0')  (' SMAD1%0'  ' MDM2_g%0')  (' SMAD1%0'  ' BAX%0')  (' SMAD1%0'  ' PRKACA%0')  (' SMAD1%0'  ' TGFB1%0')  (' SMAD1%0'  ' MAP3K8%0')  (' SMAD1%0'  ' TSC_f%0')  (' SMAD1%0'  ' SMAD4%0')  (' SMAD1%0'  ' BAD%0')  (' SMAD1%0'  ' MAP3K5%0')  (' SMAD1%0'  ' AKT1S1%0')  (' SMAD1%0'  ' SKI%0')  (' SMAD1%0'  ' SMAD3%0')  (' SMAD1%0'  ' MAPKAPK2%0')  (' SMAD1%0'  ' DUSP1_g%0')  (' SMAD1%0'  ' MSK_f%0')  (' SMAD1%0'  ' GRAP2%0')  (' SMAD1%0'  ' TAB_f%0')  (' SMAD1%0'  ' ATF2%0')  (' SMAD1%0'  ' SMAD5%0')  (' SMAD1%0'  ' FOS%0')  (' SMAD1%0'  ' JUN%0')  (' SMAD1%0'  ' MAP3K7%0')  (' SMAD1%0'  ' NLK%0')  (' SMAD1%0'  ' SMAD7_g%0')  (' SMAD1%0'  ' SMAD6_g%0')  (' SMAD1%0'  ' AP1_c%0')  (' SMAD1%0'  ' ACVR1%0')  (' SMAD1%0'  ' PTPN6%0')  (' SMAD1%0'  ' CDC42%0')  (' SMAD1%0'  ' GRB2%0')  (' SMAD1%0'  ' TGFBR1%0')  (' SMAD1%0'  ' SMURF1%0')  (' SMAD1%0'  ' SMURF2%0')  (' SMAD1%0'  ' RHOA%0')  (' SMAD1%0'  ' BMPR2%0')  (' SMAD1%0'  ' PARD6A%0')  (' SMAD1%0'  ' DAAM1%0')  (' SMAD1%0'  ' SFRP1_g%0')  (' SMAD1%0'  ' PPM1A%0')  (' SMAD1%0'  ' CFL_f%0')  (' SMAD1%0'  ' PAK1%0')  (' SMAD1%0'  ' MAP3K11%0')  (' SMAD1%0'  ' MAP3K4%0')  (' SMAD1%0'  ' LIMK1%0')  (' SMAD1%0'  ' ROCK1%0')  (' SMAD1%0'  ' ITCH%0')  (' SMAD1%0'  ' ARHGAP24%0')  (' SMAD1%0'  ' TIAM1%0')  (' SMAD1%0'  ' RND3%0')  (' SMAD1%0'  ' MAPK8IP3%0')  (' SMAD1%0'  ' MXD1%0')  (' SMAD1%0'  ' PIP3%0')  (' FOS%0'  ' SRC%0')  (' FOS%0'  ' CSK%0')  (' FOS%0'  ' CHUK%0')  (' FOS%0'  ' RAC_f%0')  (' FOS%0'  ' DUSP1%0')  (' FOS%0'  ' TGFBR2%0')  (' FOS%0'  ' ILR_f%0')  (' FOS%0'  ' SYK%0')  (' FOS%0'  ' IRAK1%0')  (' FOS%0'  ' SHC1%0')  (' FOS%0'  ' JAK_f%0')  (' FOS%0'  ' CBPp300_c%0')  (' FOS%0'  ' SKP2%0')  (' FOS%0'  ' TP53%0')  (' FOS%0'  ' SMAD7%0')  (' FOS%0'  ' SMAD6%0')  (' FOS%0'  ' DKK_f%0')  (' FOS%0'  ' FOXO_f%0')  (' FOS%0'  ' TCF7_f%0')  (' FOS%0'  ' DKK_g%0')  (' FOS%0'  ' MYC%0')  (' FOS%0'  ' CCND1%0')  (' FOS%0'  ' EGR1%0')  (' FOS%0'  ' MMP_f%0')  (' FOS%0'  ' PTEN_g%0')  (' FOS%0'  ' RTPK_f%0')  (' FOS%0'  ' CTNNB1%0')  (' FOS%0'  'LEF1%0')  (' FOS%0'  'SFRP1%0')  (' FOS%0'  'FZD_f%0')  (' FOS%0'  ' CASP8%0')  (' FOS%0'  ' REL_f%0')  (' FOS%0'  ' NFKB_f%0')  (' FOS%0'  ' DVL_f%0')  (' FOS%0'  ' LRP_f%0')  (' FOS%0'  ' BTRC%0')  (' FOS%0'  ' CK1_f%0')  (' FOS%0'  ' AXIN1%0')  (' FOS%0'  ' mTORC2_c%0')  (' FOS%0'  ' PDPK1%0')  (' FOS%0'  ' MEK_f%0')  (' FOS%0'  ' CYCS%0')  (' FOS%0'  ' CASP9%0')  (' FOS%0'  ' GSK3_f%0')  (' FOS%0'  ' IRS1%0')  (' FOS%0'  ' MDM2%0')  (' FOS%0'  ' AKT_f%0')  (' FOS%0'  ' BCL2%0')  (' FOS%0'  ' RAF_f%0')  (' FOS%0'  ' mTORC1_c%0')  (' FOS%0'  ' RHEB%0')  (' FOS%0'  ' RTPK_g%0')  (' FOS%0'  ' PTEN%0')  (' FOS%0'  ' CASP3%0')  (' FOS%0'  ' PIK3CA%0')  (' FOS%0'  ' CREBBP%0')  (' FOS%0'  ' PTPN11%0')  (' FOS%0'  ' KRAS%0')  (' FOS%0'  ' MAP2K4%0')  (' FOS%0'  ' MAP2K7%0')  (' FOS%0'  ' MAPK14%0')  (' FOS%0'  ' JNK_f%0')  (' FOS%0'  ' MAP2K3%0')  (' FOS%0'  ' ERK_f%0')  (' FOS%0'  ' LIF%0')  (' FOS%0'  ' PPP1CA%0')  (' FOS%0'  ' GAB_f%0')  (' FOS%0'  ' SOS1%0')  (' FOS%0'  ' PRKCA%0')  (' FOS%0'  ' VAV1%0')  (' FOS%0'  ' PLCG1%0')  (' FOS%0'  ' PRKCD%0')  (' FOS%0'  ' RSK_f%0')  (' FOS%0'  ' S6K_f%0')  (' FOS%0'  ' PLK1%0')  (' FOS%0'  ' ILK%0')  (' FOS%0'  ' SOCS1%0')  (' FOS%0'  ' DUSP6%0')  (' FOS%0'  ' STAT3%0')  (' FOS%0'  ' LIMK2%0')  (' FOS%0'  ' EP300%0')  (' FOS%0'  ' STAT1%0')  (' FOS%0'  ' IKBKB%0')  (' FOS%0'  ' SRF%0')  (' FOS%0'  ' PIAS1%0')  (' FOS%0'  ' TRAF6%0')  (' FOS%0'  ' SOCS1_g%0')  (' FOS%0'  ' ISGF3_c%0')  (' FOS%0'  ' STAT2%0')  (' FOS%0'  ' CFLAR%0')  (' FOS%0'  ' SMAD2%0')  (' FOS%0'  ' MDM2_g%0')  (' FOS%0'  ' BAX%0')  (' FOS%0'  ' PRKACA%0')  (' FOS%0'  ' TGFB1%0')  (' FOS%0'  ' MAP3K8%0')  (' FOS%0'  ' TSC_f%0')  (' FOS%0'  ' SMAD4%0')  (' FOS%0'  ' BAD%0')  (' FOS%0'  ' MAP3K5%0')  (' FOS%0'  ' AKT1S1%0')  (' FOS%0'  ' SKI%0')  (' FOS%0'  ' SMAD3%0')  (' FOS%0'  ' MAPKAPK2%0')  (' FOS%0'  ' DUSP1_g%0')  (' FOS%0'  ' MSK_f%0')  (' FOS%0'  ' GRAP2%0')  (' FOS%0'  ' TAB_f%0')  (' FOS%0'  ' ATF2%0')  (' FOS%0'  ' SMAD5%0')  (' FOS%0'  ' SMAD1%0')  (' FOS%0'  ' JUN%0')  (' FOS%0'  ' MAP3K7%0')  (' FOS%0'  ' NLK%0')  (' FOS%0'  ' SMAD7_g%0')  (' FOS%0'  ' SMAD6_g%0')  (' FOS%0'  ' AP1_c%0')  (' FOS%0'  ' ACVR1%0')  (' FOS%0'  ' PTPN6%0')  (' FOS%0'  ' CDC42%0')  (' FOS%0'  ' GRB2%0')  (' FOS%0'  ' TGFBR1%0')  (' FOS%0'  ' SMURF1%0')  (' FOS%0'  ' SMURF2%0')  (' FOS%0'  ' RHOA%0')  (' FOS%0'  ' BMPR2%0')  (' FOS%0'  ' PARD6A%0')  (' FOS%0'  ' DAAM1%0')  (' FOS%0'  ' SFRP1_g%0')  (' FOS%0'  ' PPM1A%0')  (' FOS%0'  ' CFL_f%0')  (' FOS%0'  ' PAK1%0')  (' FOS%0'  ' MAP3K11%0')  (' FOS%0'  ' MAP3K4%0')  (' FOS%0'  ' LIMK1%0')  (' FOS%0'  ' ROCK1%0')  (' FOS%0'  ' ITCH%0')  (' FOS%0'  ' ARHGAP24%0')  (' FOS%0'  ' TIAM1%0')  (' FOS%0'  ' RND3%0')  (' FOS%0'  ' MAPK8IP3%0')  (' FOS%0'  ' MXD1%0')  (' FOS%0'  ' PIP3%0')  (' JUN%0'  ' SRC%0')  (' JUN%0'  ' CSK%0')  (' JUN%0'  ' CHUK%0')  (' JUN%0'  ' RAC_f%0')  (' JUN%0'  ' DUSP1%0')  (' JUN%0'  ' TGFBR2%0')  (' JUN%0'  ' ILR_f%0')  (' JUN%0'  ' SYK%0')  (' JUN%0'  ' IRAK1%0')  (' JUN%0'  ' SHC1%0')  (' JUN%0'  ' JAK_f%0')  (' JUN%0'  ' CBPp300_c%0')  (' JUN%0'  ' SKP2%0')  (' JUN%0'  ' TP53%0')  (' JUN%0'  ' SMAD7%0')  (' JUN%0'  ' SMAD6%0')  (' JUN%0'  ' DKK_f%0')  (' JUN%0'  ' FOXO_f%0')  (' JUN%0'  ' TCF7_f%0')  (' JUN%0'  ' DKK_g%0')  (' JUN%0'  ' MYC%0')  (' JUN%0'  ' CCND1%0')  (' JUN%0'  ' EGR1%0')  (' JUN%0'  ' MMP_f%0')  (' JUN%0'  ' PTEN_g%0')  (' JUN%0'  ' RTPK_f%0')  (' JUN%0'  ' CTNNB1%0')  (' JUN%0'  'LEF1%0')  (' JUN%0'  'SFRP1%0')  (' JUN%0'  'FZD_f%0')  (' JUN%0'  ' CASP8%0')  (' JUN%0'  ' REL_f%0')  (' JUN%0'  ' NFKB_f%0')  (' JUN%0'  ' DVL_f%0')  (' JUN%0'  ' LRP_f%0')  (' JUN%0'  ' BTRC%0')  (' JUN%0'  ' CK1_f%0')  (' JUN%0'  ' AXIN1%0')  (' JUN%0'  ' mTORC2_c%0')  (' JUN%0'  ' PDPK1%0')  (' JUN%0'  ' MEK_f%0')  (' JUN%0'  ' CYCS%0')  (' JUN%0'  ' CASP9%0')  (' JUN%0'  ' GSK3_f%0')  (' JUN%0'  ' IRS1%0')  (' JUN%0'  ' MDM2%0')  (' JUN%0'  ' AKT_f%0')  (' JUN%0'  ' BCL2%0')  (' JUN%0'  ' RAF_f%0')  (' JUN%0'  ' mTORC1_c%0')  (' JUN%0'  ' RHEB%0')  (' JUN%0'  ' RTPK_g%0')  (' JUN%0'  ' PTEN%0')  (' JUN%0'  ' CASP3%0')  (' JUN%0'  ' PIK3CA%0')  (' JUN%0'  ' CREBBP%0')  (' JUN%0'  ' PTPN11%0')  (' JUN%0'  ' KRAS%0')  (' JUN%0'  ' MAP2K4%0')  (' JUN%0'  ' MAP2K7%0')  (' JUN%0'  ' MAPK14%0')  (' JUN%0'  ' JNK_f%0')  (' JUN%0'  ' MAP2K3%0')  (' JUN%0'  ' ERK_f%0')  (' JUN%0'  ' LIF%0')  (' JUN%0'  ' PPP1CA%0')  (' JUN%0'  ' GAB_f%0')  (' JUN%0'  ' SOS1%0')  (' JUN%0'  ' PRKCA%0')  (' JUN%0'  ' VAV1%0')  (' JUN%0'  ' PLCG1%0')  (' JUN%0'  ' PRKCD%0')  (' JUN%0'  ' RSK_f%0')  (' JUN%0'  ' S6K_f%0')  (' JUN%0'  ' PLK1%0')  (' JUN%0'  ' ILK%0')  (' JUN%0'  ' SOCS1%0')  (' JUN%0'  ' DUSP6%0')  (' JUN%0'  ' STAT3%0')  (' JUN%0'  ' LIMK2%0')  (' JUN%0'  ' EP300%0')  (' JUN%0'  ' STAT1%0')  (' JUN%0'  ' IKBKB%0')  (' JUN%0'  ' SRF%0')  (' JUN%0'  ' PIAS1%0')  (' JUN%0'  ' TRAF6%0')  (' JUN%0'  ' SOCS1_g%0')  (' JUN%0'  ' ISGF3_c%0')  (' JUN%0'  ' STAT2%0')  (' JUN%0'  ' CFLAR%0')  (' JUN%0'  ' SMAD2%0')  (' JUN%0'  ' MDM2_g%0')  (' JUN%0'  ' BAX%0')  (' JUN%0'  ' PRKACA%0')  (' JUN%0'  ' TGFB1%0')  (' JUN%0'  ' MAP3K8%0')  (' JUN%0'  ' TSC_f%0')  (' JUN%0'  ' SMAD4%0')  (' JUN%0'  ' BAD%0')  (' JUN%0'  ' MAP3K5%0')  (' JUN%0'  ' AKT1S1%0')  (' JUN%0'  ' SKI%0')  (' JUN%0'  ' SMAD3%0')  (' JUN%0'  ' MAPKAPK2%0')  (' JUN%0'  ' DUSP1_g%0')  (' JUN%0'  ' MSK_f%0')  (' JUN%0'  ' GRAP2%0')  (' JUN%0'  ' TAB_f%0')  (' JUN%0'  ' ATF2%0')  (' JUN%0'  ' SMAD5%0')  (' JUN%0'  ' SMAD1%0')  (' JUN%0'  ' FOS%0')  (' JUN%0'  ' MAP3K7%0')  (' JUN%0'  ' NLK%0')  (' JUN%0'  ' SMAD7_g%0')  (' JUN%0'  ' SMAD6_g%0')  (' JUN%0'  ' AP1_c%0')  (' JUN%0'  ' ACVR1%0')  (' JUN%0'  ' PTPN6%0')  (' JUN%0'  ' CDC42%0')  (' JUN%0'  ' GRB2%0')  (' JUN%0'  ' TGFBR1%0')  (' JUN%0'  ' SMURF1%0')  (' JUN%0'  ' SMURF2%0')  (' JUN%0'  ' RHOA%0')  (' JUN%0'  ' BMPR2%0')  (' JUN%0'  ' PARD6A%0')  (' JUN%0'  ' DAAM1%0')  (' JUN%0'  ' SFRP1_g%0')  (' JUN%0'  ' PPM1A%0')  (' JUN%0'  ' CFL_f%0')  (' JUN%0'  ' PAK1%0')  (' JUN%0'  ' MAP3K11%0')  (' JUN%0'  ' MAP3K4%0')  (' JUN%0'  ' LIMK1%0')  (' JUN%0'  ' ROCK1%0')  (' JUN%0'  ' ITCH%0')  (' JUN%0'  ' ARHGAP24%0')  (' JUN%0'  ' TIAM1%0')  (' JUN%0'  ' RND3%0')  (' JUN%0'  ' MAPK8IP3%0')  (' JUN%0'  ' MXD1%0')  (' JUN%0'  ' PIP3%0')  (' MAP3K7%0'  ' SRC%0')  (' MAP3K7%0'  ' CSK%0')  (' MAP3K7%0'  ' CHUK%0')  (' MAP3K7%0'  ' RAC_f%0')  (' MAP3K7%0'  ' DUSP1%0')  (' MAP3K7%0'  ' TGFBR2%0')  (' MAP3K7%0'  ' ILR_f%0')  (' MAP3K7%0'  ' SYK%0')  (' MAP3K7%0'  ' IRAK1%0')  (' MAP3K7%0'  ' SHC1%0')  (' MAP3K7%0'  ' JAK_f%0')  (' MAP3K7%0'  ' CBPp300_c%0')  (' MAP3K7%0'  ' SKP2%0')  (' MAP3K7%0'  ' TP53%0')  (' MAP3K7%0'  ' SMAD7%0')  (' MAP3K7%0'  ' SMAD6%0')  (' MAP3K7%0'  ' DKK_f%0')  (' MAP3K7%0'  ' FOXO_f%0')  (' MAP3K7%0'  ' TCF7_f%0')  (' MAP3K7%0'  ' DKK_g%0')  (' MAP3K7%0'  ' MYC%0')  (' MAP3K7%0'  ' CCND1%0')  (' MAP3K7%0'  ' EGR1%0')  (' MAP3K7%0'  ' MMP_f%0')  (' MAP3K7%0'  ' PTEN_g%0')  (' MAP3K7%0'  ' RTPK_f%0')  (' MAP3K7%0'  ' CTNNB1%0')  (' MAP3K7%0'  'LEF1%0')  (' MAP3K7%0'  'SFRP1%0')  (' MAP3K7%0'  'FZD_f%0')  (' MAP3K7%0'  ' CASP8%0')  (' MAP3K7%0'  ' REL_f%0')  (' MAP3K7%0'  ' NFKB_f%0')  (' MAP3K7%0'  ' DVL_f%0')  (' MAP3K7%0'  ' LRP_f%0')  (' MAP3K7%0'  ' BTRC%0')  (' MAP3K7%0'  ' CK1_f%0')  (' MAP3K7%0'  ' AXIN1%0')  (' MAP3K7%0'  ' mTORC2_c%0')  (' MAP3K7%0'  ' PDPK1%0')  (' MAP3K7%0'  ' MEK_f%0')  (' MAP3K7%0'  ' CYCS%0')  (' MAP3K7%0'  ' CASP9%0')  (' MAP3K7%0'  ' GSK3_f%0')  (' MAP3K7%0'  ' IRS1%0')  (' MAP3K7%0'  ' MDM2%0')  (' MAP3K7%0'  ' AKT_f%0')  (' MAP3K7%0'  ' BCL2%0')  (' MAP3K7%0'  ' RAF_f%0')  (' MAP3K7%0'  ' mTORC1_c%0')  (' MAP3K7%0'  ' RHEB%0')  (' MAP3K7%0'  ' RTPK_g%0')  (' MAP3K7%0'  ' PTEN%0')  (' MAP3K7%0'  ' CASP3%0')  (' MAP3K7%0'  ' PIK3CA%0')  (' MAP3K7%0'  ' CREBBP%0')  (' MAP3K7%0'  ' PTPN11%0')  (' MAP3K7%0'  ' KRAS%0')  (' MAP3K7%0'  ' MAP2K4%0')  (' MAP3K7%0'  ' MAP2K7%0')  (' MAP3K7%0'  ' MAPK14%0')  (' MAP3K7%0'  ' JNK_f%0')  (' MAP3K7%0'  ' MAP2K3%0')  (' MAP3K7%0'  ' ERK_f%0')  (' MAP3K7%0'  ' LIF%0')  (' MAP3K7%0'  ' PPP1CA%0')  (' MAP3K7%0'  ' GAB_f%0')  (' MAP3K7%0'  ' SOS1%0')  (' MAP3K7%0'  ' PRKCA%0')  (' MAP3K7%0'  ' VAV1%0')  (' MAP3K7%0'  ' PLCG1%0')  (' MAP3K7%0'  ' PRKCD%0')  (' MAP3K7%0'  ' RSK_f%0')  (' MAP3K7%0'  ' S6K_f%0')  (' MAP3K7%0'  ' PLK1%0')  (' MAP3K7%0'  ' ILK%0')  (' MAP3K7%0'  ' SOCS1%0')  (' MAP3K7%0'  ' DUSP6%0')  (' MAP3K7%0'  ' STAT3%0')  (' MAP3K7%0'  ' LIMK2%0')  (' MAP3K7%0'  ' EP300%0')  (' MAP3K7%0'  ' STAT1%0')  (' MAP3K7%0'  ' IKBKB%0')  (' MAP3K7%0'  ' SRF%0')  (' MAP3K7%0'  ' PIAS1%0')  (' MAP3K7%0'  ' TRAF6%0')  (' MAP3K7%0'  ' SOCS1_g%0')  (' MAP3K7%0'  ' ISGF3_c%0')  (' MAP3K7%0'  ' STAT2%0')  (' MAP3K7%0'  ' CFLAR%0')  (' MAP3K7%0'  ' SMAD2%0')  (' MAP3K7%0'  ' MDM2_g%0')  (' MAP3K7%0'  ' BAX%0')  (' MAP3K7%0'  ' PRKACA%0')  (' MAP3K7%0'  ' TGFB1%0')  (' MAP3K7%0'  ' MAP3K8%0')  (' MAP3K7%0'  ' TSC_f%0')  (' MAP3K7%0'  ' SMAD4%0')  (' MAP3K7%0'  ' BAD%0')  (' MAP3K7%0'  ' MAP3K5%0')  (' MAP3K7%0'  ' AKT1S1%0')  (' MAP3K7%0'  ' SKI%0')  (' MAP3K7%0'  ' SMAD3%0')  (' MAP3K7%0'  ' MAPKAPK2%0')  (' MAP3K7%0'  ' DUSP1_g%0')  (' MAP3K7%0'  ' MSK_f%0')  (' MAP3K7%0'  ' GRAP2%0')  (' MAP3K7%0'  ' TAB_f%0')  (' MAP3K7%0'  ' ATF2%0')  (' MAP3K7%0'  ' SMAD5%0')  (' MAP3K7%0'  ' SMAD1%0')  (' MAP3K7%0'  ' FOS%0')  (' MAP3K7%0'  ' JUN%0')  (' MAP3K7%0'  ' NLK%0')  (' MAP3K7%0'  ' SMAD7_g%0')  (' MAP3K7%0'  ' SMAD6_g%0')  (' MAP3K7%0'  ' AP1_c%0')  (' MAP3K7%0'  ' ACVR1%0')  (' MAP3K7%0'  ' PTPN6%0')  (' MAP3K7%0'  ' CDC42%0')  (' MAP3K7%0'  ' GRB2%0')  (' MAP3K7%0'  ' TGFBR1%0')  (' MAP3K7%0'  ' SMURF1%0')  (' MAP3K7%0'  ' SMURF2%0')  (' MAP3K7%0'  ' RHOA%0')  (' MAP3K7%0'  ' BMPR2%0')  (' MAP3K7%0'  ' PARD6A%0')  (' MAP3K7%0'  ' DAAM1%0')  (' MAP3K7%0'  ' SFRP1_g%0')  (' MAP3K7%0'  ' PPM1A%0')  (' MAP3K7%0'  ' CFL_f%0')  (' MAP3K7%0'  ' PAK1%0')  (' MAP3K7%0'  ' MAP3K11%0')  (' MAP3K7%0'  ' MAP3K4%0')  (' MAP3K7%0'  ' LIMK1%0')  (' MAP3K7%0'  ' ROCK1%0')  (' MAP3K7%0'  ' ITCH%0')  (' MAP3K7%0'  ' ARHGAP24%0')  (' MAP3K7%0'  ' TIAM1%0')  (' MAP3K7%0'  ' RND3%0')  (' MAP3K7%0'  ' MAPK8IP3%0')  (' MAP3K7%0'  ' MXD1%0')  (' MAP3K7%0'  ' PIP3%0')  (' NLK%0'  ' SRC%0')  (' NLK%0'  ' CSK%0')  (' NLK%0'  ' CHUK%0')  (' NLK%0'  ' RAC_f%0')  (' NLK%0'  ' DUSP1%0')  (' NLK%0'  ' TGFBR2%0')  (' NLK%0'  ' ILR_f%0')  (' NLK%0'  ' SYK%0')  (' NLK%0'  ' IRAK1%0')  (' NLK%0'  ' SHC1%0')  (' NLK%0'  ' JAK_f%0')  (' NLK%0'  ' CBPp300_c%0')  (' NLK%0'  ' SKP2%0')  (' NLK%0'  ' TP53%0')  (' NLK%0'  ' SMAD7%0')  (' NLK%0'  ' SMAD6%0')  (' NLK%0'  ' DKK_f%0')  (' NLK%0'  ' FOXO_f%0')  (' NLK%0'  ' TCF7_f%0')  (' NLK%0'  ' DKK_g%0')  (' NLK%0'  ' MYC%0')  (' NLK%0'  ' CCND1%0')  (' NLK%0'  ' EGR1%0')  (' NLK%0'  ' MMP_f%0')  (' NLK%0'  ' PTEN_g%0')  (' NLK%0'  ' RTPK_f%0')  (' NLK%0'  ' CTNNB1%0')  (' NLK%0'  'LEF1%0')  (' NLK%0'  'SFRP1%0')  (' NLK%0'  'FZD_f%0')  (' NLK%0'  ' CASP8%0')  (' NLK%0'  ' REL_f%0')  (' NLK%0'  ' NFKB_f%0')  (' NLK%0'  ' DVL_f%0')  (' NLK%0'  ' LRP_f%0')  (' NLK%0'  ' BTRC%0')  (' NLK%0'  ' CK1_f%0')  (' NLK%0'  ' AXIN1%0')  (' NLK%0'  ' mTORC2_c%0')  (' NLK%0'  ' PDPK1%0')  (' NLK%0'  ' MEK_f%0')  (' NLK%0'  ' CYCS%0')  (' NLK%0'  ' CASP9%0')  (' NLK%0'  ' GSK3_f%0')  (' NLK%0'  ' IRS1%0')  (' NLK%0'  ' MDM2%0')  (' NLK%0'  ' AKT_f%0')  (' NLK%0'  ' BCL2%0')  (' NLK%0'  ' RAF_f%0')  (' NLK%0'  ' mTORC1_c%0')  (' NLK%0'  ' RHEB%0')  (' NLK%0'  ' RTPK_g%0')  (' NLK%0'  ' PTEN%0')  (' NLK%0'  ' CASP3%0')  (' NLK%0'  ' PIK3CA%0')  (' NLK%0'  ' CREBBP%0')  (' NLK%0'  ' PTPN11%0')  (' NLK%0'  ' KRAS%0')  (' NLK%0'  ' MAP2K4%0')  (' NLK%0'  ' MAP2K7%0')  (' NLK%0'  ' MAPK14%0')  (' NLK%0'  ' JNK_f%0')  (' NLK%0'  ' MAP2K3%0')  (' NLK%0'  ' ERK_f%0')  (' NLK%0'  ' LIF%0')  (' NLK%0'  ' PPP1CA%0')  (' NLK%0'  ' GAB_f%0')  (' NLK%0'  ' SOS1%0')  (' NLK%0'  ' PRKCA%0')  (' NLK%0'  ' VAV1%0')  (' NLK%0'  ' PLCG1%0')  (' NLK%0'  ' PRKCD%0')  (' NLK%0'  ' RSK_f%0')  (' NLK%0'  ' S6K_f%0')  (' NLK%0'  ' PLK1%0')  (' NLK%0'  ' ILK%0')  (' NLK%0'  ' SOCS1%0')  (' NLK%0'  ' DUSP6%0')  (' NLK%0'  ' STAT3%0')  (' NLK%0'  ' LIMK2%0')  (' NLK%0'  ' EP300%0')  (' NLK%0'  ' STAT1%0')  (' NLK%0'  ' IKBKB%0')  (' NLK%0'  ' SRF%0')  (' NLK%0'  ' PIAS1%0')  (' NLK%0'  ' TRAF6%0')  (' NLK%0'  ' SOCS1_g%0')  (' NLK%0'  ' ISGF3_c%0')  (' NLK%0'  ' STAT2%0')  (' NLK%0'  ' CFLAR%0')  (' NLK%0'  ' SMAD2%0')  (' NLK%0'  ' MDM2_g%0')  (' NLK%0'  ' BAX%0')  (' NLK%0'  ' PRKACA%0')  (' NLK%0'  ' TGFB1%0')  (' NLK%0'  ' MAP3K8%0')  (' NLK%0'  ' TSC_f%0')  (' NLK%0'  ' SMAD4%0')  (' NLK%0'  ' BAD%0')  (' NLK%0'  ' MAP3K5%0')  (' NLK%0'  ' AKT1S1%0')  (' NLK%0'  ' SKI%0')  (' NLK%0'  ' SMAD3%0')  (' NLK%0'  ' MAPKAPK2%0')  (' NLK%0'  ' DUSP1_g%0')  (' NLK%0'  ' MSK_f%0')  (' NLK%0'  ' GRAP2%0')  (' NLK%0'  ' TAB_f%0')  (' NLK%0'  ' ATF2%0')  (' NLK%0'  ' SMAD5%0')  (' NLK%0'  ' SMAD1%0')  (' NLK%0'  ' FOS%0')  (' NLK%0'  ' JUN%0')  (' NLK%0'  ' MAP3K7%0')  (' NLK%0'  ' SMAD7_g%0')  (' NLK%0'  ' SMAD6_g%0')  (' NLK%0'  ' AP1_c%0')  (' NLK%0'  ' ACVR1%0')  (' NLK%0'  ' PTPN6%0')  (' NLK%0'  ' CDC42%0')  (' NLK%0'  ' GRB2%0')  (' NLK%0'  ' TGFBR1%0')  (' NLK%0'  ' SMURF1%0')  (' NLK%0'  ' SMURF2%0')  (' NLK%0'  ' RHOA%0')  (' NLK%0'  ' BMPR2%0')  (' NLK%0'  ' PARD6A%0')  (' NLK%0'  ' DAAM1%0')  (' NLK%0'  ' SFRP1_g%0')  (' NLK%0'  ' PPM1A%0')  (' NLK%0'  ' CFL_f%0')  (' NLK%0'  ' PAK1%0')  (' NLK%0'  ' MAP3K11%0')  (' NLK%0'  ' MAP3K4%0')  (' NLK%0'  ' LIMK1%0')  (' NLK%0'  ' ROCK1%0')  (' NLK%0'  ' ITCH%0')  (' NLK%0'  ' ARHGAP24%0')  (' NLK%0'  ' TIAM1%0')  (' NLK%0'  ' RND3%0')  (' NLK%0'  ' MAPK8IP3%0')  (' NLK%0'  ' MXD1%0')  (' NLK%0'  ' PIP3%0')  (' SMAD7_g%0'  ' SRC%0')  (' SMAD7_g%0'  ' CSK%0')  (' SMAD7_g%0'  ' CHUK%0')  (' SMAD7_g%0'  ' RAC_f%0')  (' SMAD7_g%0'  ' DUSP1%0')  (' SMAD7_g%0'  ' TGFBR2%0')  (' SMAD7_g%0'  ' ILR_f%0')  (' SMAD7_g%0'  ' SYK%0')  (' SMAD7_g%0'  ' IRAK1%0')  (' SMAD7_g%0'  ' SHC1%0')  (' SMAD7_g%0'  ' JAK_f%0')  (' SMAD7_g%0'  ' CBPp300_c%0')  (' SMAD7_g%0'  ' SKP2%0')  (' SMAD7_g%0'  ' TP53%0')  (' SMAD7_g%0'  ' SMAD7%0')  (' SMAD7_g%0'  ' SMAD6%0')  (' SMAD7_g%0'  ' DKK_f%0')  (' SMAD7_g%0'  ' FOXO_f%0')  (' SMAD7_g%0'  ' TCF7_f%0')  (' SMAD7_g%0'  ' DKK_g%0')  (' SMAD7_g%0'  ' MYC%0')  (' SMAD7_g%0'  ' CCND1%0')  (' SMAD7_g%0'  ' EGR1%0')  (' SMAD7_g%0'  ' MMP_f%0')  (' SMAD7_g%0'  ' PTEN_g%0')  (' SMAD7_g%0'  ' RTPK_f%0')  (' SMAD7_g%0'  ' CTNNB1%0')  (' SMAD7_g%0'  'LEF1%0')  (' SMAD7_g%0'  'SFRP1%0')  (' SMAD7_g%0'  'FZD_f%0')  (' SMAD7_g%0'  ' CASP8%0')  (' SMAD7_g%0'  ' REL_f%0')  (' SMAD7_g%0'  ' NFKB_f%0')  (' SMAD7_g%0'  ' DVL_f%0')  (' SMAD7_g%0'  ' LRP_f%0')  (' SMAD7_g%0'  ' BTRC%0')  (' SMAD7_g%0'  ' CK1_f%0')  (' SMAD7_g%0'  ' AXIN1%0')  (' SMAD7_g%0'  ' mTORC2_c%0')  (' SMAD7_g%0'  ' PDPK1%0')  (' SMAD7_g%0'  ' MEK_f%0')  (' SMAD7_g%0'  ' CYCS%0')  (' SMAD7_g%0'  ' CASP9%0')  (' SMAD7_g%0'  ' GSK3_f%0')  (' SMAD7_g%0'  ' IRS1%0')  (' SMAD7_g%0'  ' MDM2%0')  (' SMAD7_g%0'  ' AKT_f%0')  (' SMAD7_g%0'  ' BCL2%0')  (' SMAD7_g%0'  ' RAF_f%0')  (' SMAD7_g%0'  ' mTORC1_c%0')  (' SMAD7_g%0'  ' RHEB%0')  (' SMAD7_g%0'  ' RTPK_g%0')  (' SMAD7_g%0'  ' PTEN%0')  (' SMAD7_g%0'  ' CASP3%0')  (' SMAD7_g%0'  ' PIK3CA%0')  (' SMAD7_g%0'  ' CREBBP%0')  (' SMAD7_g%0'  ' PTPN11%0')  (' SMAD7_g%0'  ' KRAS%0')  (' SMAD7_g%0'  ' MAP2K4%0')  (' SMAD7_g%0'  ' MAP2K7%0')  (' SMAD7_g%0'  ' MAPK14%0')  (' SMAD7_g%0'  ' JNK_f%0')  (' SMAD7_g%0'  ' MAP2K3%0')  (' SMAD7_g%0'  ' ERK_f%0')  (' SMAD7_g%0'  ' LIF%0')  (' SMAD7_g%0'  ' PPP1CA%0')  (' SMAD7_g%0'  ' GAB_f%0')  (' SMAD7_g%0'  ' SOS1%0')  (' SMAD7_g%0'  ' PRKCA%0')  (' SMAD7_g%0'  ' VAV1%0')  (' SMAD7_g%0'  ' PLCG1%0')  (' SMAD7_g%0'  ' PRKCD%0')  (' SMAD7_g%0'  ' RSK_f%0')  (' SMAD7_g%0'  ' S6K_f%0')  (' SMAD7_g%0'  ' PLK1%0')  (' SMAD7_g%0'  ' ILK%0')  (' SMAD7_g%0'  ' SOCS1%0')  (' SMAD7_g%0'  ' DUSP6%0')  (' SMAD7_g%0'  ' STAT3%0')  (' SMAD7_g%0'  ' LIMK2%0')  (' SMAD7_g%0'  ' EP300%0')  (' SMAD7_g%0'  ' STAT1%0')  (' SMAD7_g%0'  ' IKBKB%0')  (' SMAD7_g%0'  ' SRF%0')  (' SMAD7_g%0'  ' PIAS1%0')  (' SMAD7_g%0'  ' TRAF6%0')  (' SMAD7_g%0'  ' SOCS1_g%0')  (' SMAD7_g%0'  ' ISGF3_c%0')  (' SMAD7_g%0'  ' STAT2%0')  (' SMAD7_g%0'  ' CFLAR%0')  (' SMAD7_g%0'  ' SMAD2%0')  (' SMAD7_g%0'  ' MDM2_g%0')  (' SMAD7_g%0'  ' BAX%0')  (' SMAD7_g%0'  ' PRKACA%0')  (' SMAD7_g%0'  ' TGFB1%0')  (' SMAD7_g%0'  ' MAP3K8%0')  (' SMAD7_g%0'  ' TSC_f%0')  (' SMAD7_g%0'  ' SMAD4%0')  (' SMAD7_g%0'  ' BAD%0')  (' SMAD7_g%0'  ' MAP3K5%0')  (' SMAD7_g%0'  ' AKT1S1%0')  (' SMAD7_g%0'  ' SKI%0')  (' SMAD7_g%0'  ' SMAD3%0')  (' SMAD7_g%0'  ' MAPKAPK2%0')  (' SMAD7_g%0'  ' DUSP1_g%0')  (' SMAD7_g%0'  ' MSK_f%0')  (' SMAD7_g%0'  ' GRAP2%0')  (' SMAD7_g%0'  ' TAB_f%0')  (' SMAD7_g%0'  ' ATF2%0')  (' SMAD7_g%0'  ' SMAD5%0')  (' SMAD7_g%0'  ' SMAD1%0')  (' SMAD7_g%0'  ' FOS%0')  (' SMAD7_g%0'  ' JUN%0')  (' SMAD7_g%0'  ' MAP3K7%0')  (' SMAD7_g%0'  ' NLK%0')  (' SMAD7_g%0'  ' SMAD6_g%0')  (' SMAD7_g%0'  ' AP1_c%0')  (' SMAD7_g%0'  ' ACVR1%0')  (' SMAD7_g%0'  ' PTPN6%0')  (' SMAD7_g%0'  ' CDC42%0')  (' SMAD7_g%0'  ' GRB2%0')  (' SMAD7_g%0'  ' TGFBR1%0')  (' SMAD7_g%0'  ' SMURF1%0')  (' SMAD7_g%0'  ' SMURF2%0')  (' SMAD7_g%0'  ' RHOA%0')  (' SMAD7_g%0'  ' BMPR2%0')  (' SMAD7_g%0'  ' PARD6A%0')  (' SMAD7_g%0'  ' DAAM1%0')  (' SMAD7_g%0'  ' SFRP1_g%0')  (' SMAD7_g%0'  ' PPM1A%0')  (' SMAD7_g%0'  ' CFL_f%0')  (' SMAD7_g%0'  ' PAK1%0')  (' SMAD7_g%0'  ' MAP3K11%0')  (' SMAD7_g%0'  ' MAP3K4%0')  (' SMAD7_g%0'  ' LIMK1%0')  (' SMAD7_g%0'  ' ROCK1%0')  (' SMAD7_g%0'  ' ITCH%0')  (' SMAD7_g%0'  ' ARHGAP24%0')  (' SMAD7_g%0'  ' TIAM1%0')  (' SMAD7_g%0'  ' RND3%0')  (' SMAD7_g%0'  ' MAPK8IP3%0')  (' SMAD7_g%0'  ' MXD1%0')  (' SMAD7_g%0'  ' PIP3%0')  (' SMAD6_g%0'  ' SRC%0')  (' SMAD6_g%0'  ' CSK%0')  (' SMAD6_g%0'  ' CHUK%0')  (' SMAD6_g%0'  ' RAC_f%0')  (' SMAD6_g%0'  ' DUSP1%0')  (' SMAD6_g%0'  ' TGFBR2%0')  (' SMAD6_g%0'  ' ILR_f%0')  (' SMAD6_g%0'  ' SYK%0')  (' SMAD6_g%0'  ' IRAK1%0')  (' SMAD6_g%0'  ' SHC1%0')  (' SMAD6_g%0'  ' JAK_f%0')  (' SMAD6_g%0'  ' CBPp300_c%0')  (' SMAD6_g%0'  ' SKP2%0')  (' SMAD6_g%0'  ' TP53%0')  (' SMAD6_g%0'  ' SMAD7%0')  (' SMAD6_g%0'  ' SMAD6%0')  (' SMAD6_g%0'  ' DKK_f%0')  (' SMAD6_g%0'  ' FOXO_f%0')  (' SMAD6_g%0'  ' TCF7_f%0')  (' SMAD6_g%0'  ' DKK_g%0')  (' SMAD6_g%0'  ' MYC%0')  (' SMAD6_g%0'  ' CCND1%0')  (' SMAD6_g%0'  ' EGR1%0')  (' SMAD6_g%0'  ' MMP_f%0')  (' SMAD6_g%0'  ' PTEN_g%0')  (' SMAD6_g%0'  ' RTPK_f%0')  (' SMAD6_g%0'  ' CTNNB1%0')  (' SMAD6_g%0'  'LEF1%0')  (' SMAD6_g%0'  'SFRP1%0')  (' SMAD6_g%0'  'FZD_f%0')  (' SMAD6_g%0'  ' CASP8%0')  (' SMAD6_g%0'  ' REL_f%0')  (' SMAD6_g%0'  ' NFKB_f%0')  (' SMAD6_g%0'  ' DVL_f%0')  (' SMAD6_g%0'  ' LRP_f%0')  (' SMAD6_g%0'  ' BTRC%0')  (' SMAD6_g%0'  ' CK1_f%0')  (' SMAD6_g%0'  ' AXIN1%0')  (' SMAD6_g%0'  ' mTORC2_c%0')  (' SMAD6_g%0'  ' PDPK1%0')  (' SMAD6_g%0'  ' MEK_f%0')  (' SMAD6_g%0'  ' CYCS%0')  (' SMAD6_g%0'  ' CASP9%0')  (' SMAD6_g%0'  ' GSK3_f%0')  (' SMAD6_g%0'  ' IRS1%0')  (' SMAD6_g%0'  ' MDM2%0')  (' SMAD6_g%0'  ' AKT_f%0')  (' SMAD6_g%0'  ' BCL2%0')  (' SMAD6_g%0'  ' RAF_f%0')  (' SMAD6_g%0'  ' mTORC1_c%0')  (' SMAD6_g%0'  ' RHEB%0')  (' SMAD6_g%0'  ' RTPK_g%0')  (' SMAD6_g%0'  ' PTEN%0')  (' SMAD6_g%0'  ' CASP3%0')  (' SMAD6_g%0'  ' PIK3CA%0')  (' SMAD6_g%0'  ' CREBBP%0')  (' SMAD6_g%0'  ' PTPN11%0')  (' SMAD6_g%0'  ' KRAS%0')  (' SMAD6_g%0'  ' MAP2K4%0')  (' SMAD6_g%0'  ' MAP2K7%0')  (' SMAD6_g%0'  ' MAPK14%0')  (' SMAD6_g%0'  ' JNK_f%0')  (' SMAD6_g%0'  ' MAP2K3%0')  (' SMAD6_g%0'  ' ERK_f%0')  (' SMAD6_g%0'  ' LIF%0')  (' SMAD6_g%0'  ' PPP1CA%0')  (' SMAD6_g%0'  ' GAB_f%0')  (' SMAD6_g%0'  ' SOS1%0')  (' SMAD6_g%0'  ' PRKCA%0')  (' SMAD6_g%0'  ' VAV1%0')  (' SMAD6_g%0'  ' PLCG1%0')  (' SMAD6_g%0'  ' PRKCD%0')  (' SMAD6_g%0'  ' RSK_f%0')  (' SMAD6_g%0'  ' S6K_f%0')  (' SMAD6_g%0'  ' PLK1%0')  (' SMAD6_g%0'  ' ILK%0')  (' SMAD6_g%0'  ' SOCS1%0')  (' SMAD6_g%0'  ' DUSP6%0')  (' SMAD6_g%0'  ' STAT3%0')  (' SMAD6_g%0'  ' LIMK2%0')  (' SMAD6_g%0'  ' EP300%0')  (' SMAD6_g%0'  ' STAT1%0')  (' SMAD6_g%0'  ' IKBKB%0')  (' SMAD6_g%0'  ' SRF%0')  (' SMAD6_g%0'  ' PIAS1%0')  (' SMAD6_g%0'  ' TRAF6%0')  (' SMAD6_g%0'  ' SOCS1_g%0')  (' SMAD6_g%0'  ' ISGF3_c%0')  (' SMAD6_g%0'  ' STAT2%0')  (' SMAD6_g%0'  ' CFLAR%0')  (' SMAD6_g%0'  ' SMAD2%0')  (' SMAD6_g%0'  ' MDM2_g%0')  (' SMAD6_g%0'  ' BAX%0')  (' SMAD6_g%0'  ' PRKACA%0')  (' SMAD6_g%0'  ' TGFB1%0')  (' SMAD6_g%0'  ' MAP3K8%0')  (' SMAD6_g%0'  ' TSC_f%0')  (' SMAD6_g%0'  ' SMAD4%0')  (' SMAD6_g%0'  ' BAD%0')  (' SMAD6_g%0'  ' MAP3K5%0')  (' SMAD6_g%0'  ' AKT1S1%0')  (' SMAD6_g%0'  ' SKI%0')  (' SMAD6_g%0'  ' SMAD3%0')  (' SMAD6_g%0'  ' MAPKAPK2%0')  (' SMAD6_g%0'  ' DUSP1_g%0')  (' SMAD6_g%0'  ' MSK_f%0')  (' SMAD6_g%0'  ' GRAP2%0')  (' SMAD6_g%0'  ' TAB_f%0')  (' SMAD6_g%0'  ' ATF2%0')  (' SMAD6_g%0'  ' SMAD5%0')  (' SMAD6_g%0'  ' SMAD1%0')  (' SMAD6_g%0'  ' FOS%0')  (' SMAD6_g%0'  ' JUN%0')  (' SMAD6_g%0'  ' MAP3K7%0')  (' SMAD6_g%0'  ' NLK%0')  (' SMAD6_g%0'  ' SMAD7_g%0')  (' SMAD6_g%0'  ' AP1_c%0')  (' SMAD6_g%0'  ' ACVR1%0')  (' SMAD6_g%0'  ' PTPN6%0')  (' SMAD6_g%0'  ' CDC42%0')  (' SMAD6_g%0'  ' GRB2%0')  (' SMAD6_g%0'  ' TGFBR1%0')  (' SMAD6_g%0'  ' SMURF1%0')  (' SMAD6_g%0'  ' SMURF2%0')  (' SMAD6_g%0'  ' RHOA%0')  (' SMAD6_g%0'  ' BMPR2%0')  (' SMAD6_g%0'  ' PARD6A%0')  (' SMAD6_g%0'  ' DAAM1%0')  (' SMAD6_g%0'  ' SFRP1_g%0')  (' SMAD6_g%0'  ' PPM1A%0')  (' SMAD6_g%0'  ' CFL_f%0')  (' SMAD6_g%0'  ' PAK1%0')  (' SMAD6_g%0'  ' MAP3K11%0')  (' SMAD6_g%0'  ' MAP3K4%0')  (' SMAD6_g%0'  ' LIMK1%0')  (' SMAD6_g%0'  ' ROCK1%0')  (' SMAD6_g%0'  ' ITCH%0')  (' SMAD6_g%0'  ' ARHGAP24%0')  (' SMAD6_g%0'  ' TIAM1%0')  (' SMAD6_g%0'  ' RND3%0')  (' SMAD6_g%0'  ' MAPK8IP3%0')  (' SMAD6_g%0'  ' MXD1%0')  (' SMAD6_g%0'  ' PIP3%0')  (' AP1_c%0'  ' SRC%0')  (' AP1_c%0'  ' CSK%0')  (' AP1_c%0'  ' CHUK%0')  (' AP1_c%0'  ' RAC_f%0')  (' AP1_c%0'  ' DUSP1%0')  (' AP1_c%0'  ' TGFBR2%0')  (' AP1_c%0'  ' ILR_f%0')  (' AP1_c%0'  ' SYK%0')  (' AP1_c%0'  ' IRAK1%0')  (' AP1_c%0'  ' SHC1%0')  (' AP1_c%0'  ' JAK_f%0')  (' AP1_c%0'  ' CBPp300_c%0')  (' AP1_c%0'  ' SKP2%0')  (' AP1_c%0'  ' TP53%0')  (' AP1_c%0'  ' SMAD7%0')  (' AP1_c%0'  ' SMAD6%0')  (' AP1_c%0'  ' DKK_f%0')  (' AP1_c%0'  ' FOXO_f%0')  (' AP1_c%0'  ' TCF7_f%0')  (' AP1_c%0'  ' DKK_g%0')  (' AP1_c%0'  ' MYC%0')  (' AP1_c%0'  ' CCND1%0')  (' AP1_c%0'  ' EGR1%0')  (' AP1_c%0'  ' MMP_f%0')  (' AP1_c%0'  ' PTEN_g%0')  (' AP1_c%0'  ' RTPK_f%0')  (' AP1_c%0'  ' CTNNB1%0')  (' AP1_c%0'  'LEF1%0')  (' AP1_c%0'  'SFRP1%0')  (' AP1_c%0'  'FZD_f%0')  (' AP1_c%0'  ' CASP8%0')  (' AP1_c%0'  ' REL_f%0')  (' AP1_c%0'  ' NFKB_f%0')  (' AP1_c%0'  ' DVL_f%0')  (' AP1_c%0'  ' LRP_f%0')  (' AP1_c%0'  ' BTRC%0')  (' AP1_c%0'  ' CK1_f%0')  (' AP1_c%0'  ' AXIN1%0')  (' AP1_c%0'  ' mTORC2_c%0')  (' AP1_c%0'  ' PDPK1%0')  (' AP1_c%0'  ' MEK_f%0')  (' AP1_c%0'  ' CYCS%0')  (' AP1_c%0'  ' CASP9%0')  (' AP1_c%0'  ' GSK3_f%0')  (' AP1_c%0'  ' IRS1%0')  (' AP1_c%0'  ' MDM2%0')  (' AP1_c%0'  ' AKT_f%0')  (' AP1_c%0'  ' BCL2%0')  (' AP1_c%0'  ' RAF_f%0')  (' AP1_c%0'  ' mTORC1_c%0')  (' AP1_c%0'  ' RHEB%0')  (' AP1_c%0'  ' RTPK_g%0')  (' AP1_c%0'  ' PTEN%0')  (' AP1_c%0'  ' CASP3%0')  (' AP1_c%0'  ' PIK3CA%0')  (' AP1_c%0'  ' CREBBP%0')  (' AP1_c%0'  ' PTPN11%0')  (' AP1_c%0'  ' KRAS%0')  (' AP1_c%0'  ' MAP2K4%0')  (' AP1_c%0'  ' MAP2K7%0')  (' AP1_c%0'  ' MAPK14%0')  (' AP1_c%0'  ' JNK_f%0')  (' AP1_c%0'  ' MAP2K3%0')  (' AP1_c%0'  ' ERK_f%0')  (' AP1_c%0'  ' LIF%0')  (' AP1_c%0'  ' PPP1CA%0')  (' AP1_c%0'  ' GAB_f%0')  (' AP1_c%0'  ' SOS1%0')  (' AP1_c%0'  ' PRKCA%0')  (' AP1_c%0'  ' VAV1%0')  (' AP1_c%0'  ' PLCG1%0')  (' AP1_c%0'  ' PRKCD%0')  (' AP1_c%0'  ' RSK_f%0')  (' AP1_c%0'  ' S6K_f%0')  (' AP1_c%0'  ' PLK1%0')  (' AP1_c%0'  ' ILK%0')  (' AP1_c%0'  ' SOCS1%0')  (' AP1_c%0'  ' DUSP6%0')  (' AP1_c%0'  ' STAT3%0')  (' AP1_c%0'  ' LIMK2%0')  (' AP1_c%0'  ' EP300%0')  (' AP1_c%0'  ' STAT1%0')  (' AP1_c%0'  ' IKBKB%0')  (' AP1_c%0'  ' SRF%0')  (' AP1_c%0'  ' PIAS1%0')  (' AP1_c%0'  ' TRAF6%0')  (' AP1_c%0'  ' SOCS1_g%0')  (' AP1_c%0'  ' ISGF3_c%0')  (' AP1_c%0'  ' STAT2%0')  (' AP1_c%0'  ' CFLAR%0')  (' AP1_c%0'  ' SMAD2%0')  (' AP1_c%0'  ' MDM2_g%0')  (' AP1_c%0'  ' BAX%0')  (' AP1_c%0'  ' PRKACA%0')  (' AP1_c%0'  ' TGFB1%0')  (' AP1_c%0'  ' MAP3K8%0')  (' AP1_c%0'  ' TSC_f%0')  (' AP1_c%0'  ' SMAD4%0')  (' AP1_c%0'  ' BAD%0')  (' AP1_c%0'  ' MAP3K5%0')  (' AP1_c%0'  ' AKT1S1%0')  (' AP1_c%0'  ' SKI%0')  (' AP1_c%0'  ' SMAD3%0')  (' AP1_c%0'  ' MAPKAPK2%0')  (' AP1_c%0'  ' DUSP1_g%0')  (' AP1_c%0'  ' MSK_f%0')  (' AP1_c%0'  ' GRAP2%0')  (' AP1_c%0'  ' TAB_f%0')  (' AP1_c%0'  ' ATF2%0')  (' AP1_c%0'  ' SMAD5%0')  (' AP1_c%0'  ' SMAD1%0')  (' AP1_c%0'  ' FOS%0')  (' AP1_c%0'  ' JUN%0')  (' AP1_c%0'  ' MAP3K7%0')  (' AP1_c%0'  ' NLK%0')  (' AP1_c%0'  ' SMAD7_g%0')  (' AP1_c%0'  ' SMAD6_g%0')  (' AP1_c%0'  ' ACVR1%0')  (' AP1_c%0'  ' PTPN6%0')  (' AP1_c%0'  ' CDC42%0')  (' AP1_c%0'  ' GRB2%0')  (' AP1_c%0'  ' TGFBR1%0')  (' AP1_c%0'  ' SMURF1%0')  (' AP1_c%0'  ' SMURF2%0')  (' AP1_c%0'  ' RHOA%0')  (' AP1_c%0'  ' BMPR2%0')  (' AP1_c%0'  ' PARD6A%0')  (' AP1_c%0'  ' DAAM1%0')  (' AP1_c%0'  ' SFRP1_g%0')  (' AP1_c%0'  ' PPM1A%0')  (' AP1_c%0'  ' CFL_f%0')  (' AP1_c%0'  ' PAK1%0')  (' AP1_c%0'  ' MAP3K11%0')  (' AP1_c%0'  ' MAP3K4%0')  (' AP1_c%0'  ' LIMK1%0')  (' AP1_c%0'  ' ROCK1%0')  (' AP1_c%0'  ' ITCH%0')  (' AP1_c%0'  ' ARHGAP24%0')  (' AP1_c%0'  ' TIAM1%0')  (' AP1_c%0'  ' RND3%0')  (' AP1_c%0'  ' MAPK8IP3%0')  (' AP1_c%0'  ' MXD1%0')  (' AP1_c%0'  ' PIP3%0')  (' ACVR1%0'  ' SRC%0')  (' ACVR1%0'  ' CSK%0')  (' ACVR1%0'  ' CHUK%0')  (' ACVR1%0'  ' RAC_f%0')  (' ACVR1%0'  ' DUSP1%0')  (' ACVR1%0'  ' TGFBR2%0')  (' ACVR1%0'  ' ILR_f%0')  (' ACVR1%0'  ' SYK%0')  (' ACVR1%0'  ' IRAK1%0')  (' ACVR1%0'  ' SHC1%0')  (' ACVR1%0'  ' JAK_f%0')  (' ACVR1%0'  ' CBPp300_c%0')  (' ACVR1%0'  ' SKP2%0')  (' ACVR1%0'  ' TP53%0')  (' ACVR1%0'  ' SMAD7%0')  (' ACVR1%0'  ' SMAD6%0')  (' ACVR1%0'  ' DKK_f%0')  (' ACVR1%0'  ' FOXO_f%0')  (' ACVR1%0'  ' TCF7_f%0')  (' ACVR1%0'  ' DKK_g%0')  (' ACVR1%0'  ' MYC%0')  (' ACVR1%0'  ' CCND1%0')  (' ACVR1%0'  ' EGR1%0')  (' ACVR1%0'  ' MMP_f%0')  (' ACVR1%0'  ' PTEN_g%0')  (' ACVR1%0'  ' RTPK_f%0')  (' ACVR1%0'  ' CTNNB1%0')  (' ACVR1%0'  'LEF1%0')  (' ACVR1%0'  'SFRP1%0')  (' ACVR1%0'  'FZD_f%0')  (' ACVR1%0'  ' CASP8%0')  (' ACVR1%0'  ' REL_f%0')  (' ACVR1%0'  ' NFKB_f%0')  (' ACVR1%0'  ' DVL_f%0')  (' ACVR1%0'  ' LRP_f%0')  (' ACVR1%0'  ' BTRC%0')  (' ACVR1%0'  ' CK1_f%0')  (' ACVR1%0'  ' AXIN1%0')  (' ACVR1%0'  ' mTORC2_c%0')  (' ACVR1%0'  ' PDPK1%0')  (' ACVR1%0'  ' MEK_f%0')  (' ACVR1%0'  ' CYCS%0')  (' ACVR1%0'  ' CASP9%0')  (' ACVR1%0'  ' GSK3_f%0')  (' ACVR1%0'  ' IRS1%0')  (' ACVR1%0'  ' MDM2%0')  (' ACVR1%0'  ' AKT_f%0')  (' ACVR1%0'  ' BCL2%0')  (' ACVR1%0'  ' RAF_f%0')  (' ACVR1%0'  ' mTORC1_c%0')  (' ACVR1%0'  ' RHEB%0')  (' ACVR1%0'  ' RTPK_g%0')  (' ACVR1%0'  ' PTEN%0')  (' ACVR1%0'  ' CASP3%0')  (' ACVR1%0'  ' PIK3CA%0')  (' ACVR1%0'  ' CREBBP%0')  (' ACVR1%0'  ' PTPN11%0')  (' ACVR1%0'  ' KRAS%0')  (' ACVR1%0'  ' MAP2K4%0')  (' ACVR1%0'  ' MAP2K7%0')  (' ACVR1%0'  ' MAPK14%0')  (' ACVR1%0'  ' JNK_f%0')  (' ACVR1%0'  ' MAP2K3%0')  (' ACVR1%0'  ' ERK_f%0')  (' ACVR1%0'  ' LIF%0')  (' ACVR1%0'  ' PPP1CA%0')  (' ACVR1%0'  ' GAB_f%0')  (' ACVR1%0'  ' SOS1%0')  (' ACVR1%0'  ' PRKCA%0')  (' ACVR1%0'  ' VAV1%0')  (' ACVR1%0'  ' PLCG1%0')  (' ACVR1%0'  ' PRKCD%0')  (' ACVR1%0'  ' RSK_f%0')  (' ACVR1%0'  ' S6K_f%0')  (' ACVR1%0'  ' PLK1%0')  (' ACVR1%0'  ' ILK%0')  (' ACVR1%0'  ' SOCS1%0')  (' ACVR1%0'  ' DUSP6%0')  (' ACVR1%0'  ' STAT3%0')  (' ACVR1%0'  ' LIMK2%0')  (' ACVR1%0'  ' EP300%0')  (' ACVR1%0'  ' STAT1%0')  (' ACVR1%0'  ' IKBKB%0')  (' ACVR1%0'  ' SRF%0')  (' ACVR1%0'  ' PIAS1%0')  (' ACVR1%0'  ' TRAF6%0')  (' ACVR1%0'  ' SOCS1_g%0')  (' ACVR1%0'  ' ISGF3_c%0')  (' ACVR1%0'  ' STAT2%0')  (' ACVR1%0'  ' CFLAR%0')  (' ACVR1%0'  ' SMAD2%0')  (' ACVR1%0'  ' MDM2_g%0')  (' ACVR1%0'  ' BAX%0')  (' ACVR1%0'  ' PRKACA%0')  (' ACVR1%0'  ' TGFB1%0')  (' ACVR1%0'  ' MAP3K8%0')  (' ACVR1%0'  ' TSC_f%0')  (' ACVR1%0'  ' SMAD4%0')  (' ACVR1%0'  ' BAD%0')  (' ACVR1%0'  ' MAP3K5%0')  (' ACVR1%0'  ' AKT1S1%0')  (' ACVR1%0'  ' SKI%0')  (' ACVR1%0'  ' SMAD3%0')  (' ACVR1%0'  ' MAPKAPK2%0')  (' ACVR1%0'  ' DUSP1_g%0')  (' ACVR1%0'  ' MSK_f%0')  (' ACVR1%0'  ' GRAP2%0')  (' ACVR1%0'  ' TAB_f%0')  (' ACVR1%0'  ' ATF2%0')  (' ACVR1%0'  ' SMAD5%0')  (' ACVR1%0'  ' SMAD1%0')  (' ACVR1%0'  ' FOS%0')  (' ACVR1%0'  ' JUN%0')  (' ACVR1%0'  ' MAP3K7%0')  (' ACVR1%0'  ' NLK%0')  (' ACVR1%0'  ' SMAD7_g%0')  (' ACVR1%0'  ' SMAD6_g%0')  (' ACVR1%0'  ' AP1_c%0')  (' ACVR1%0'  ' PTPN6%0')  (' ACVR1%0'  ' CDC42%0')  (' ACVR1%0'  ' GRB2%0')  (' ACVR1%0'  ' TGFBR1%0')  (' ACVR1%0'  ' SMURF1%0')  (' ACVR1%0'  ' SMURF2%0')  (' ACVR1%0'  ' RHOA%0')  (' ACVR1%0'  ' BMPR2%0')  (' ACVR1%0'  ' PARD6A%0')  (' ACVR1%0'  ' DAAM1%0')  (' ACVR1%0'  ' SFRP1_g%0')  (' ACVR1%0'  ' PPM1A%0')  (' ACVR1%0'  ' CFL_f%0')  (' ACVR1%0'  ' PAK1%0')  (' ACVR1%0'  ' MAP3K11%0')  (' ACVR1%0'  ' MAP3K4%0')  (' ACVR1%0'  ' LIMK1%0')  (' ACVR1%0'  ' ROCK1%0')  (' ACVR1%0'  ' ITCH%0')  (' ACVR1%0'  ' ARHGAP24%0')  (' ACVR1%0'  ' TIAM1%0')  (' ACVR1%0'  ' RND3%0')  (' ACVR1%0'  ' MAPK8IP3%0')  (' ACVR1%0'  ' MXD1%0')  (' ACVR1%0'  ' PIP3%0')  (' PTPN6%0'  ' SRC%0')  (' PTPN6%0'  ' CSK%0')  (' PTPN6%0'  ' CHUK%0')  (' PTPN6%0'  ' RAC_f%0')  (' PTPN6%0'  ' DUSP1%0')  (' PTPN6%0'  ' TGFBR2%0')  (' PTPN6%0'  ' ILR_f%0')  (' PTPN6%0'  ' SYK%0')  (' PTPN6%0'  ' IRAK1%0')  (' PTPN6%0'  ' SHC1%0')  (' PTPN6%0'  ' JAK_f%0')  (' PTPN6%0'  ' CBPp300_c%0')  (' PTPN6%0'  ' SKP2%0')  (' PTPN6%0'  ' TP53%0')  (' PTPN6%0'  ' SMAD7%0')  (' PTPN6%0'  ' SMAD6%0')  (' PTPN6%0'  ' DKK_f%0')  (' PTPN6%0'  ' FOXO_f%0')  (' PTPN6%0'  ' TCF7_f%0')  (' PTPN6%0'  ' DKK_g%0')  (' PTPN6%0'  ' MYC%0')  (' PTPN6%0'  ' CCND1%0')  (' PTPN6%0'  ' EGR1%0')  (' PTPN6%0'  ' MMP_f%0')  (' PTPN6%0'  ' PTEN_g%0')  (' PTPN6%0'  ' RTPK_f%0')  (' PTPN6%0'  ' CTNNB1%0')  (' PTPN6%0'  'LEF1%0')  (' PTPN6%0'  'SFRP1%0')  (' PTPN6%0'  'FZD_f%0')  (' PTPN6%0'  ' CASP8%0')  (' PTPN6%0'  ' REL_f%0')  (' PTPN6%0'  ' NFKB_f%0')  (' PTPN6%0'  ' DVL_f%0')  (' PTPN6%0'  ' LRP_f%0')  (' PTPN6%0'  ' BTRC%0')  (' PTPN6%0'  ' CK1_f%0')  (' PTPN6%0'  ' AXIN1%0')  (' PTPN6%0'  ' mTORC2_c%0')  (' PTPN6%0'  ' PDPK1%0')  (' PTPN6%0'  ' MEK_f%0')  (' PTPN6%0'  ' CYCS%0')  (' PTPN6%0'  ' CASP9%0')  (' PTPN6%0'  ' GSK3_f%0')  (' PTPN6%0'  ' IRS1%0')  (' PTPN6%0'  ' MDM2%0')  (' PTPN6%0'  ' AKT_f%0')  (' PTPN6%0'  ' BCL2%0')  (' PTPN6%0'  ' RAF_f%0')  (' PTPN6%0'  ' mTORC1_c%0')  (' PTPN6%0'  ' RHEB%0')  (' PTPN6%0'  ' RTPK_g%0')  (' PTPN6%0'  ' PTEN%0')  (' PTPN6%0'  ' CASP3%0')  (' PTPN6%0'  ' PIK3CA%0')  (' PTPN6%0'  ' CREBBP%0')  (' PTPN6%0'  ' PTPN11%0')  (' PTPN6%0'  ' KRAS%0')  (' PTPN6%0'  ' MAP2K4%0')  (' PTPN6%0'  ' MAP2K7%0')  (' PTPN6%0'  ' MAPK14%0')  (' PTPN6%0'  ' JNK_f%0')  (' PTPN6%0'  ' MAP2K3%0')  (' PTPN6%0'  ' ERK_f%0')  (' PTPN6%0'  ' LIF%0')  (' PTPN6%0'  ' PPP1CA%0')  (' PTPN6%0'  ' GAB_f%0')  (' PTPN6%0'  ' SOS1%0')  (' PTPN6%0'  ' PRKCA%0')  (' PTPN6%0'  ' VAV1%0')  (' PTPN6%0'  ' PLCG1%0')  (' PTPN6%0'  ' PRKCD%0')  (' PTPN6%0'  ' RSK_f%0')  (' PTPN6%0'  ' S6K_f%0')  (' PTPN6%0'  ' PLK1%0')  (' PTPN6%0'  ' ILK%0')  (' PTPN6%0'  ' SOCS1%0')  (' PTPN6%0'  ' DUSP6%0')  (' PTPN6%0'  ' STAT3%0')  (' PTPN6%0'  ' LIMK2%0')  (' PTPN6%0'  ' EP300%0')  (' PTPN6%0'  ' STAT1%0')  (' PTPN6%0'  ' IKBKB%0')  (' PTPN6%0'  ' SRF%0')  (' PTPN6%0'  ' PIAS1%0')  (' PTPN6%0'  ' TRAF6%0')  (' PTPN6%0'  ' SOCS1_g%0')  (' PTPN6%0'  ' ISGF3_c%0')  (' PTPN6%0'  ' STAT2%0')  (' PTPN6%0'  ' CFLAR%0')  (' PTPN6%0'  ' SMAD2%0')  (' PTPN6%0'  ' MDM2_g%0')  (' PTPN6%0'  ' BAX%0')  (' PTPN6%0'  ' PRKACA%0')  (' PTPN6%0'  ' TGFB1%0')  (' PTPN6%0'  ' MAP3K8%0')  (' PTPN6%0'  ' TSC_f%0')  (' PTPN6%0'  ' SMAD4%0')  (' PTPN6%0'  ' BAD%0')  (' PTPN6%0'  ' MAP3K5%0')  (' PTPN6%0'  ' AKT1S1%0')  (' PTPN6%0'  ' SKI%0')  (' PTPN6%0'  ' SMAD3%0')  (' PTPN6%0'  ' MAPKAPK2%0')  (' PTPN6%0'  ' DUSP1_g%0')  (' PTPN6%0'  ' MSK_f%0')  (' PTPN6%0'  ' GRAP2%0')  (' PTPN6%0'  ' TAB_f%0')  (' PTPN6%0'  ' ATF2%0')  (' PTPN6%0'  ' SMAD5%0')  (' PTPN6%0'  ' SMAD1%0')  (' PTPN6%0'  ' FOS%0')  (' PTPN6%0'  ' JUN%0')  (' PTPN6%0'  ' MAP3K7%0')  (' PTPN6%0'  ' NLK%0')  (' PTPN6%0'  ' SMAD7_g%0')  (' PTPN6%0'  ' SMAD6_g%0')  (' PTPN6%0'  ' AP1_c%0')  (' PTPN6%0'  ' ACVR1%0')  (' PTPN6%0'  ' CDC42%0')  (' PTPN6%0'  ' GRB2%0')  (' PTPN6%0'  ' TGFBR1%0')  (' PTPN6%0'  ' SMURF1%0')  (' PTPN6%0'  ' SMURF2%0')  (' PTPN6%0'  ' RHOA%0')  (' PTPN6%0'  ' BMPR2%0')  (' PTPN6%0'  ' PARD6A%0')  (' PTPN6%0'  ' DAAM1%0')  (' PTPN6%0'  ' SFRP1_g%0')  (' PTPN6%0'  ' PPM1A%0')  (' PTPN6%0'  ' CFL_f%0')  (' PTPN6%0'  ' PAK1%0')  (' PTPN6%0'  ' MAP3K11%0')  (' PTPN6%0'  ' MAP3K4%0')  (' PTPN6%0'  ' LIMK1%0')  (' PTPN6%0'  ' ROCK1%0')  (' PTPN6%0'  ' ITCH%0')  (' PTPN6%0'  ' ARHGAP24%0')  (' PTPN6%0'  ' TIAM1%0')  (' PTPN6%0'  ' RND3%0')  (' PTPN6%0'  ' MAPK8IP3%0')  (' PTPN6%0'  ' MXD1%0')  (' PTPN6%0'  ' PIP3%0')  (' CDC42%0'  ' SRC%0')  (' CDC42%0'  ' CSK%0')  (' CDC42%0'  ' CHUK%0')  (' CDC42%0'  ' RAC_f%0')  (' CDC42%0'  ' DUSP1%0')  (' CDC42%0'  ' TGFBR2%0')  (' CDC42%0'  ' ILR_f%0')  (' CDC42%0'  ' SYK%0')  (' CDC42%0'  ' IRAK1%0')  (' CDC42%0'  ' SHC1%0')  (' CDC42%0'  ' JAK_f%0')  (' CDC42%0'  ' CBPp300_c%0')  (' CDC42%0'  ' SKP2%0')  (' CDC42%0'  ' TP53%0')  (' CDC42%0'  ' SMAD7%0')  (' CDC42%0'  ' SMAD6%0')  (' CDC42%0'  ' DKK_f%0')  (' CDC42%0'  ' FOXO_f%0')  (' CDC42%0'  ' TCF7_f%0')  (' CDC42%0'  ' DKK_g%0')  (' CDC42%0'  ' MYC%0')  (' CDC42%0'  ' CCND1%0')  (' CDC42%0'  ' EGR1%0')  (' CDC42%0'  ' MMP_f%0')  (' CDC42%0'  ' PTEN_g%0')  (' CDC42%0'  ' RTPK_f%0')  (' CDC42%0'  ' CTNNB1%0')  (' CDC42%0'  'LEF1%0')  (' CDC42%0'  'SFRP1%0')  (' CDC42%0'  'FZD_f%0')  (' CDC42%0'  ' CASP8%0')  (' CDC42%0'  ' REL_f%0')  (' CDC42%0'  ' NFKB_f%0')  (' CDC42%0'  ' DVL_f%0')  (' CDC42%0'  ' LRP_f%0')  (' CDC42%0'  ' BTRC%0')  (' CDC42%0'  ' CK1_f%0')  (' CDC42%0'  ' AXIN1%0')  (' CDC42%0'  ' mTORC2_c%0')  (' CDC42%0'  ' PDPK1%0')  (' CDC42%0'  ' MEK_f%0')  (' CDC42%0'  ' CYCS%0')  (' CDC42%0'  ' CASP9%0')  (' CDC42%0'  ' GSK3_f%0')  (' CDC42%0'  ' IRS1%0')  (' CDC42%0'  ' MDM2%0')  (' CDC42%0'  ' AKT_f%0')  (' CDC42%0'  ' BCL2%0')  (' CDC42%0'  ' RAF_f%0')  (' CDC42%0'  ' mTORC1_c%0')  (' CDC42%0'  ' RHEB%0')  (' CDC42%0'  ' RTPK_g%0')  (' CDC42%0'  ' PTEN%0')  (' CDC42%0'  ' CASP3%0')  (' CDC42%0'  ' PIK3CA%0')  (' CDC42%0'  ' CREBBP%0')  (' CDC42%0'  ' PTPN11%0')  (' CDC42%0'  ' KRAS%0')  (' CDC42%0'  ' MAP2K4%0')  (' CDC42%0'  ' MAP2K7%0')  (' CDC42%0'  ' MAPK14%0')  (' CDC42%0'  ' JNK_f%0')  (' CDC42%0'  ' MAP2K3%0')  (' CDC42%0'  ' ERK_f%0')  (' CDC42%0'  ' LIF%0')  (' CDC42%0'  ' PPP1CA%0')  (' CDC42%0'  ' GAB_f%0')  (' CDC42%0'  ' SOS1%0')  (' CDC42%0'  ' PRKCA%0')  (' CDC42%0'  ' VAV1%0')  (' CDC42%0'  ' PLCG1%0')  (' CDC42%0'  ' PRKCD%0')  (' CDC42%0'  ' RSK_f%0')  (' CDC42%0'  ' S6K_f%0')  (' CDC42%0'  ' PLK1%0')  (' CDC42%0'  ' ILK%0')  (' CDC42%0'  ' SOCS1%0')  (' CDC42%0'  ' DUSP6%0')  (' CDC42%0'  ' STAT3%0')  (' CDC42%0'  ' LIMK2%0')  (' CDC42%0'  ' EP300%0')  (' CDC42%0'  ' STAT1%0')  (' CDC42%0'  ' IKBKB%0')  (' CDC42%0'  ' SRF%0')  (' CDC42%0'  ' PIAS1%0')  (' CDC42%0'  ' TRAF6%0')  (' CDC42%0'  ' SOCS1_g%0')  (' CDC42%0'  ' ISGF3_c%0')  (' CDC42%0'  ' STAT2%0')  (' CDC42%0'  ' CFLAR%0')  (' CDC42%0'  ' SMAD2%0')  (' CDC42%0'  ' MDM2_g%0')  (' CDC42%0'  ' BAX%0')  (' CDC42%0'  ' PRKACA%0')  (' CDC42%0'  ' TGFB1%0')  (' CDC42%0'  ' MAP3K8%0')  (' CDC42%0'  ' TSC_f%0')  (' CDC42%0'  ' SMAD4%0')  (' CDC42%0'  ' BAD%0')  (' CDC42%0'  ' MAP3K5%0')  (' CDC42%0'  ' AKT1S1%0')  (' CDC42%0'  ' SKI%0')  (' CDC42%0'  ' SMAD3%0')  (' CDC42%0'  ' MAPKAPK2%0')  (' CDC42%0'  ' DUSP1_g%0')  (' CDC42%0'  ' MSK_f%0')  (' CDC42%0'  ' GRAP2%0')  (' CDC42%0'  ' TAB_f%0')  (' CDC42%0'  ' ATF2%0')  (' CDC42%0'  ' SMAD5%0')  (' CDC42%0'  ' SMAD1%0')  (' CDC42%0'  ' FOS%0')  (' CDC42%0'  ' JUN%0')  (' CDC42%0'  ' MAP3K7%0')  (' CDC42%0'  ' NLK%0')  (' CDC42%0'  ' SMAD7_g%0')  (' CDC42%0'  ' SMAD6_g%0')  (' CDC42%0'  ' AP1_c%0')  (' CDC42%0'  ' ACVR1%0')  (' CDC42%0'  ' PTPN6%0')  (' CDC42%0'  ' GRB2%0')  (' CDC42%0'  ' TGFBR1%0')  (' CDC42%0'  ' SMURF1%0')  (' CDC42%0'  ' SMURF2%0')  (' CDC42%0'  ' RHOA%0')  (' CDC42%0'  ' BMPR2%0')  (' CDC42%0'  ' PARD6A%0')  (' CDC42%0'  ' DAAM1%0')  (' CDC42%0'  ' SFRP1_g%0')  (' CDC42%0'  ' PPM1A%0')  (' CDC42%0'  ' CFL_f%0')  (' CDC42%0'  ' PAK1%0')  (' CDC42%0'  ' MAP3K11%0')  (' CDC42%0'  ' MAP3K4%0')  (' CDC42%0'  ' LIMK1%0')  (' CDC42%0'  ' ROCK1%0')  (' CDC42%0'  ' ITCH%0')  (' CDC42%0'  ' ARHGAP24%0')  (' CDC42%0'  ' TIAM1%0')  (' CDC42%0'  ' RND3%0')  (' CDC42%0'  ' MAPK8IP3%0')  (' CDC42%0'  ' MXD1%0')  (' CDC42%0'  ' PIP3%0')  (' GRB2%0'  ' SRC%0')  (' GRB2%0'  ' CSK%0')  (' GRB2%0'  ' CHUK%0')  (' GRB2%0'  ' RAC_f%0')  (' GRB2%0'  ' DUSP1%0')  (' GRB2%0'  ' TGFBR2%0')  (' GRB2%0'  ' ILR_f%0')  (' GRB2%0'  ' SYK%0')  (' GRB2%0'  ' IRAK1%0')  (' GRB2%0'  ' SHC1%0')  (' GRB2%0'  ' JAK_f%0')  (' GRB2%0'  ' CBPp300_c%0')  (' GRB2%0'  ' SKP2%0')  (' GRB2%0'  ' TP53%0')  (' GRB2%0'  ' SMAD7%0')  (' GRB2%0'  ' SMAD6%0')  (' GRB2%0'  ' DKK_f%0')  (' GRB2%0'  ' FOXO_f%0')  (' GRB2%0'  ' TCF7_f%0')  (' GRB2%0'  ' DKK_g%0')  (' GRB2%0'  ' MYC%0')  (' GRB2%0'  ' CCND1%0')  (' GRB2%0'  ' EGR1%0')  (' GRB2%0'  ' MMP_f%0')  (' GRB2%0'  ' PTEN_g%0')  (' GRB2%0'  ' RTPK_f%0')  (' GRB2%0'  ' CTNNB1%0')  (' GRB2%0'  'LEF1%0')  (' GRB2%0'  'SFRP1%0')  (' GRB2%0'  'FZD_f%0')  (' GRB2%0'  ' CASP8%0')  (' GRB2%0'  ' REL_f%0')  (' GRB2%0'  ' NFKB_f%0')  (' GRB2%0'  ' DVL_f%0')  (' GRB2%0'  ' LRP_f%0')  (' GRB2%0'  ' BTRC%0')  (' GRB2%0'  ' CK1_f%0')  (' GRB2%0'  ' AXIN1%0')  (' GRB2%0'  ' mTORC2_c%0')  (' GRB2%0'  ' PDPK1%0')  (' GRB2%0'  ' MEK_f%0')  (' GRB2%0'  ' CYCS%0')  (' GRB2%0'  ' CASP9%0')  (' GRB2%0'  ' GSK3_f%0')  (' GRB2%0'  ' IRS1%0')  (' GRB2%0'  ' MDM2%0')  (' GRB2%0'  ' AKT_f%0')  (' GRB2%0'  ' BCL2%0')  (' GRB2%0'  ' RAF_f%0')  (' GRB2%0'  ' mTORC1_c%0')  (' GRB2%0'  ' RHEB%0')  (' GRB2%0'  ' RTPK_g%0')  (' GRB2%0'  ' PTEN%0')  (' GRB2%0'  ' CASP3%0')  (' GRB2%0'  ' PIK3CA%0')  (' GRB2%0'  ' CREBBP%0')  (' GRB2%0'  ' PTPN11%0')  (' GRB2%0'  ' KRAS%0')  (' GRB2%0'  ' MAP2K4%0')  (' GRB2%0'  ' MAP2K7%0')  (' GRB2%0'  ' MAPK14%0')  (' GRB2%0'  ' JNK_f%0')  (' GRB2%0'  ' MAP2K3%0')  (' GRB2%0'  ' ERK_f%0')  (' GRB2%0'  ' LIF%0')  (' GRB2%0'  ' PPP1CA%0')  (' GRB2%0'  ' GAB_f%0')  (' GRB2%0'  ' SOS1%0')  (' GRB2%0'  ' PRKCA%0')  (' GRB2%0'  ' VAV1%0')  (' GRB2%0'  ' PLCG1%0')  (' GRB2%0'  ' PRKCD%0')  (' GRB2%0'  ' RSK_f%0')  (' GRB2%0'  ' S6K_f%0')  (' GRB2%0'  ' PLK1%0')  (' GRB2%0'  ' ILK%0')  (' GRB2%0'  ' SOCS1%0')  (' GRB2%0'  ' DUSP6%0')  (' GRB2%0'  ' STAT3%0')  (' GRB2%0'  ' LIMK2%0')  (' GRB2%0'  ' EP300%0')  (' GRB2%0'  ' STAT1%0')  (' GRB2%0'  ' IKBKB%0')  (' GRB2%0'  ' SRF%0')  (' GRB2%0'  ' PIAS1%0')  (' GRB2%0'  ' TRAF6%0')  (' GRB2%0'  ' SOCS1_g%0')  (' GRB2%0'  ' ISGF3_c%0')  (' GRB2%0'  ' STAT2%0')  (' GRB2%0'  ' CFLAR%0')  (' GRB2%0'  ' SMAD2%0')  (' GRB2%0'  ' MDM2_g%0')  (' GRB2%0'  ' BAX%0')  (' GRB2%0'  ' PRKACA%0')  (' GRB2%0'  ' TGFB1%0')  (' GRB2%0'  ' MAP3K8%0')  (' GRB2%0'  ' TSC_f%0')  (' GRB2%0'  ' SMAD4%0')  (' GRB2%0'  ' BAD%0')  (' GRB2%0'  ' MAP3K5%0')  (' GRB2%0'  ' AKT1S1%0')  (' GRB2%0'  ' SKI%0')  (' GRB2%0'  ' SMAD3%0')  (' GRB2%0'  ' MAPKAPK2%0')  (' GRB2%0'  ' DUSP1_g%0')  (' GRB2%0'  ' MSK_f%0')  (' GRB2%0'  ' GRAP2%0')  (' GRB2%0'  ' TAB_f%0')  (' GRB2%0'  ' ATF2%0')  (' GRB2%0'  ' SMAD5%0')  (' GRB2%0'  ' SMAD1%0')  (' GRB2%0'  ' FOS%0')  (' GRB2%0'  ' JUN%0')  (' GRB2%0'  ' MAP3K7%0')  (' GRB2%0'  ' NLK%0')  (' GRB2%0'  ' SMAD7_g%0')  (' GRB2%0'  ' SMAD6_g%0')  (' GRB2%0'  ' AP1_c%0')  (' GRB2%0'  ' ACVR1%0')  (' GRB2%0'  ' PTPN6%0')  (' GRB2%0'  ' CDC42%0')  (' GRB2%0'  ' TGFBR1%0')  (' GRB2%0'  ' SMURF1%0')  (' GRB2%0'  ' SMURF2%0')  (' GRB2%0'  ' RHOA%0')  (' GRB2%0'  ' BMPR2%0')  (' GRB2%0'  ' PARD6A%0')  (' GRB2%0'  ' DAAM1%0')  (' GRB2%0'  ' SFRP1_g%0')  (' GRB2%0'  ' PPM1A%0')  (' GRB2%0'  ' CFL_f%0')  (' GRB2%0'  ' PAK1%0')  (' GRB2%0'  ' MAP3K11%0')  (' GRB2%0'  ' MAP3K4%0')  (' GRB2%0'  ' LIMK1%0')  (' GRB2%0'  ' ROCK1%0')  (' GRB2%0'  ' ITCH%0')  (' GRB2%0'  ' ARHGAP24%0')  (' GRB2%0'  ' TIAM1%0')  (' GRB2%0'  ' RND3%0')  (' GRB2%0'  ' MAPK8IP3%0')  (' GRB2%0'  ' MXD1%0')  (' GRB2%0'  ' PIP3%0')  (' TGFBR1%0'  ' SRC%0')  (' TGFBR1%0'  ' CSK%0')  (' TGFBR1%0'  ' CHUK%0')  (' TGFBR1%0'  ' RAC_f%0')  (' TGFBR1%0'  ' DUSP1%0')  (' TGFBR1%0'  ' TGFBR2%0')  (' TGFBR1%0'  ' ILR_f%0')  (' TGFBR1%0'  ' SYK%0')  (' TGFBR1%0'  ' IRAK1%0')  (' TGFBR1%0'  ' SHC1%0')  (' TGFBR1%0'  ' JAK_f%0')  (' TGFBR1%0'  ' CBPp300_c%0')  (' TGFBR1%0'  ' SKP2%0')  (' TGFBR1%0'  ' TP53%0')  (' TGFBR1%0'  ' SMAD7%0')  (' TGFBR1%0'  ' SMAD6%0')  (' TGFBR1%0'  ' DKK_f%0')  (' TGFBR1%0'  ' FOXO_f%0')  (' TGFBR1%0'  ' TCF7_f%0')  (' TGFBR1%0'  ' DKK_g%0')  (' TGFBR1%0'  ' MYC%0')  (' TGFBR1%0'  ' CCND1%0')  (' TGFBR1%0'  ' EGR1%0')  (' TGFBR1%0'  ' MMP_f%0')  (' TGFBR1%0'  ' PTEN_g%0')  (' TGFBR1%0'  ' RTPK_f%0')  (' TGFBR1%0'  ' CTNNB1%0')  (' TGFBR1%0'  'LEF1%0')  (' TGFBR1%0'  'SFRP1%0')  (' TGFBR1%0'  'FZD_f%0')  (' TGFBR1%0'  ' CASP8%0')  (' TGFBR1%0'  ' REL_f%0')  (' TGFBR1%0'  ' NFKB_f%0')  (' TGFBR1%0'  ' DVL_f%0')  (' TGFBR1%0'  ' LRP_f%0')  (' TGFBR1%0'  ' BTRC%0')  (' TGFBR1%0'  ' CK1_f%0')  (' TGFBR1%0'  ' AXIN1%0')  (' TGFBR1%0'  ' mTORC2_c%0')  (' TGFBR1%0'  ' PDPK1%0')  (' TGFBR1%0'  ' MEK_f%0')  (' TGFBR1%0'  ' CYCS%0')  (' TGFBR1%0'  ' CASP9%0')  (' TGFBR1%0'  ' GSK3_f%0')  (' TGFBR1%0'  ' IRS1%0')  (' TGFBR1%0'  ' MDM2%0')  (' TGFBR1%0'  ' AKT_f%0')  (' TGFBR1%0'  ' BCL2%0')  (' TGFBR1%0'  ' RAF_f%0')  (' TGFBR1%0'  ' mTORC1_c%0')  (' TGFBR1%0'  ' RHEB%0')  (' TGFBR1%0'  ' RTPK_g%0')  (' TGFBR1%0'  ' PTEN%0')  (' TGFBR1%0'  ' CASP3%0')  (' TGFBR1%0'  ' PIK3CA%0')  (' TGFBR1%0'  ' CREBBP%0')  (' TGFBR1%0'  ' PTPN11%0')  (' TGFBR1%0'  ' KRAS%0')  (' TGFBR1%0'  ' MAP2K4%0')  (' TGFBR1%0'  ' MAP2K7%0')  (' TGFBR1%0'  ' MAPK14%0')  (' TGFBR1%0'  ' JNK_f%0')  (' TGFBR1%0'  ' MAP2K3%0')  (' TGFBR1%0'  ' ERK_f%0')  (' TGFBR1%0'  ' LIF%0')  (' TGFBR1%0'  ' PPP1CA%0')  (' TGFBR1%0'  ' GAB_f%0')  (' TGFBR1%0'  ' SOS1%0')  (' TGFBR1%0'  ' PRKCA%0')  (' TGFBR1%0'  ' VAV1%0')  (' TGFBR1%0'  ' PLCG1%0')  (' TGFBR1%0'  ' PRKCD%0')  (' TGFBR1%0'  ' RSK_f%0')  (' TGFBR1%0'  ' S6K_f%0')  (' TGFBR1%0'  ' PLK1%0')  (' TGFBR1%0'  ' ILK%0')  (' TGFBR1%0'  ' SOCS1%0')  (' TGFBR1%0'  ' DUSP6%0')  (' TGFBR1%0'  ' STAT3%0')  (' TGFBR1%0'  ' LIMK2%0')  (' TGFBR1%0'  ' EP300%0')  (' TGFBR1%0'  ' STAT1%0')  (' TGFBR1%0'  ' IKBKB%0')  (' TGFBR1%0'  ' SRF%0')  (' TGFBR1%0'  ' PIAS1%0')  (' TGFBR1%0'  ' TRAF6%0')  (' TGFBR1%0'  ' SOCS1_g%0')  (' TGFBR1%0'  ' ISGF3_c%0')  (' TGFBR1%0'  ' STAT2%0')  (' TGFBR1%0'  ' CFLAR%0')  (' TGFBR1%0'  ' SMAD2%0')  (' TGFBR1%0'  ' MDM2_g%0')  (' TGFBR1%0'  ' BAX%0')  (' TGFBR1%0'  ' PRKACA%0')  (' TGFBR1%0'  ' TGFB1%0')  (' TGFBR1%0'  ' MAP3K8%0')  (' TGFBR1%0'  ' TSC_f%0')  (' TGFBR1%0'  ' SMAD4%0')  (' TGFBR1%0'  ' BAD%0')  (' TGFBR1%0'  ' MAP3K5%0')  (' TGFBR1%0'  ' AKT1S1%0')  (' TGFBR1%0'  ' SKI%0')  (' TGFBR1%0'  ' SMAD3%0')  (' TGFBR1%0'  ' MAPKAPK2%0')  (' TGFBR1%0'  ' DUSP1_g%0')  (' TGFBR1%0'  ' MSK_f%0')  (' TGFBR1%0'  ' GRAP2%0')  (' TGFBR1%0'  ' TAB_f%0')  (' TGFBR1%0'  ' ATF2%0')  (' TGFBR1%0'  ' SMAD5%0')  (' TGFBR1%0'  ' SMAD1%0')  (' TGFBR1%0'  ' FOS%0')  (' TGFBR1%0'  ' JUN%0')  (' TGFBR1%0'  ' MAP3K7%0')  (' TGFBR1%0'  ' NLK%0')  (' TGFBR1%0'  ' SMAD7_g%0')  (' TGFBR1%0'  ' SMAD6_g%0')  (' TGFBR1%0'  ' AP1_c%0')  (' TGFBR1%0'  ' ACVR1%0')  (' TGFBR1%0'  ' PTPN6%0')  (' TGFBR1%0'  ' CDC42%0')  (' TGFBR1%0'  ' GRB2%0')  (' TGFBR1%0'  ' SMURF1%0')  (' TGFBR1%0'  ' SMURF2%0')  (' TGFBR1%0'  ' RHOA%0')  (' TGFBR1%0'  ' BMPR2%0')  (' TGFBR1%0'  ' PARD6A%0')  (' TGFBR1%0'  ' DAAM1%0')  (' TGFBR1%0'  ' SFRP1_g%0')  (' TGFBR1%0'  ' PPM1A%0')  (' TGFBR1%0'  ' CFL_f%0')  (' TGFBR1%0'  ' PAK1%0')  (' TGFBR1%0'  ' MAP3K11%0')  (' TGFBR1%0'  ' MAP3K4%0')  (' TGFBR1%0'  ' LIMK1%0')  (' TGFBR1%0'  ' ROCK1%0')  (' TGFBR1%0'  ' ITCH%0')  (' TGFBR1%0'  ' ARHGAP24%0')  (' TGFBR1%0'  ' TIAM1%0')  (' TGFBR1%0'  ' RND3%0')  (' TGFBR1%0'  ' MAPK8IP3%0')  (' TGFBR1%0'  ' MXD1%0')  (' TGFBR1%0'  ' PIP3%0')  (' SMURF1%0'  ' SRC%0')  (' SMURF1%0'  ' CSK%0')  (' SMURF1%0'  ' CHUK%0')  (' SMURF1%0'  ' RAC_f%0')  (' SMURF1%0'  ' DUSP1%0')  (' SMURF1%0'  ' TGFBR2%0')  (' SMURF1%0'  ' ILR_f%0')  (' SMURF1%0'  ' SYK%0')  (' SMURF1%0'  ' IRAK1%0')  (' SMURF1%0'  ' SHC1%0')  (' SMURF1%0'  ' JAK_f%0')  (' SMURF1%0'  ' CBPp300_c%0')  (' SMURF1%0'  ' SKP2%0')  (' SMURF1%0'  ' TP53%0')  (' SMURF1%0'  ' SMAD7%0')  (' SMURF1%0'  ' SMAD6%0')  (' SMURF1%0'  ' DKK_f%0')  (' SMURF1%0'  ' FOXO_f%0')  (' SMURF1%0'  ' TCF7_f%0')  (' SMURF1%0'  ' DKK_g%0')  (' SMURF1%0'  ' MYC%0')  (' SMURF1%0'  ' CCND1%0')  (' SMURF1%0'  ' EGR1%0')  (' SMURF1%0'  ' MMP_f%0')  (' SMURF1%0'  ' PTEN_g%0')  (' SMURF1%0'  ' RTPK_f%0')  (' SMURF1%0'  ' CTNNB1%0')  (' SMURF1%0'  'LEF1%0')  (' SMURF1%0'  'SFRP1%0')  (' SMURF1%0'  'FZD_f%0')  (' SMURF1%0'  ' CASP8%0')  (' SMURF1%0'  ' REL_f%0')  (' SMURF1%0'  ' NFKB_f%0')  (' SMURF1%0'  ' DVL_f%0')  (' SMURF1%0'  ' LRP_f%0')  (' SMURF1%0'  ' BTRC%0')  (' SMURF1%0'  ' CK1_f%0')  (' SMURF1%0'  ' AXIN1%0')  (' SMURF1%0'  ' mTORC2_c%0')  (' SMURF1%0'  ' PDPK1%0')  (' SMURF1%0'  ' MEK_f%0')  (' SMURF1%0'  ' CYCS%0')  (' SMURF1%0'  ' CASP9%0')  (' SMURF1%0'  ' GSK3_f%0')  (' SMURF1%0'  ' IRS1%0')  (' SMURF1%0'  ' MDM2%0')  (' SMURF1%0'  ' AKT_f%0')  (' SMURF1%0'  ' BCL2%0')  (' SMURF1%0'  ' RAF_f%0')  (' SMURF1%0'  ' mTORC1_c%0')  (' SMURF1%0'  ' RHEB%0')  (' SMURF1%0'  ' RTPK_g%0')  (' SMURF1%0'  ' PTEN%0')  (' SMURF1%0'  ' CASP3%0')  (' SMURF1%0'  ' PIK3CA%0')  (' SMURF1%0'  ' CREBBP%0')  (' SMURF1%0'  ' PTPN11%0')  (' SMURF1%0'  ' KRAS%0')  (' SMURF1%0'  ' MAP2K4%0')  (' SMURF1%0'  ' MAP2K7%0')  (' SMURF1%0'  ' MAPK14%0')  (' SMURF1%0'  ' JNK_f%0')  (' SMURF1%0'  ' MAP2K3%0')  (' SMURF1%0'  ' ERK_f%0')  (' SMURF1%0'  ' LIF%0')  (' SMURF1%0'  ' PPP1CA%0')  (' SMURF1%0'  ' GAB_f%0')  (' SMURF1%0'  ' SOS1%0')  (' SMURF1%0'  ' PRKCA%0')  (' SMURF1%0'  ' VAV1%0')  (' SMURF1%0'  ' PLCG1%0')  (' SMURF1%0'  ' PRKCD%0')  (' SMURF1%0'  ' RSK_f%0')  (' SMURF1%0'  ' S6K_f%0')  (' SMURF1%0'  ' PLK1%0')  (' SMURF1%0'  ' ILK%0')  (' SMURF1%0'  ' SOCS1%0')  (' SMURF1%0'  ' DUSP6%0')  (' SMURF1%0'  ' STAT3%0')  (' SMURF1%0'  ' LIMK2%0')  (' SMURF1%0'  ' EP300%0')  (' SMURF1%0'  ' STAT1%0')  (' SMURF1%0'  ' IKBKB%0')  (' SMURF1%0'  ' SRF%0')  (' SMURF1%0'  ' PIAS1%0')  (' SMURF1%0'  ' TRAF6%0')  (' SMURF1%0'  ' SOCS1_g%0')  (' SMURF1%0'  ' ISGF3_c%0')  (' SMURF1%0'  ' STAT2%0')  (' SMURF1%0'  ' CFLAR%0')  (' SMURF1%0'  ' SMAD2%0')  (' SMURF1%0'  ' MDM2_g%0')  (' SMURF1%0'  ' BAX%0')  (' SMURF1%0'  ' PRKACA%0')  (' SMURF1%0'  ' TGFB1%0')  (' SMURF1%0'  ' MAP3K8%0')  (' SMURF1%0'  ' TSC_f%0')  (' SMURF1%0'  ' SMAD4%0')  (' SMURF1%0'  ' BAD%0')  (' SMURF1%0'  ' MAP3K5%0')  (' SMURF1%0'  ' AKT1S1%0')  (' SMURF1%0'  ' SKI%0')  (' SMURF1%0'  ' SMAD3%0')  (' SMURF1%0'  ' MAPKAPK2%0')  (' SMURF1%0'  ' DUSP1_g%0')  (' SMURF1%0'  ' MSK_f%0')  (' SMURF1%0'  ' GRAP2%0')  (' SMURF1%0'  ' TAB_f%0')  (' SMURF1%0'  ' ATF2%0')  (' SMURF1%0'  ' SMAD5%0')  (' SMURF1%0'  ' SMAD1%0')  (' SMURF1%0'  ' FOS%0')  (' SMURF1%0'  ' JUN%0')  (' SMURF1%0'  ' MAP3K7%0')  (' SMURF1%0'  ' NLK%0')  (' SMURF1%0'  ' SMAD7_g%0')  (' SMURF1%0'  ' SMAD6_g%0')  (' SMURF1%0'  ' AP1_c%0')  (' SMURF1%0'  ' ACVR1%0')  (' SMURF1%0'  ' PTPN6%0')  (' SMURF1%0'  ' CDC42%0')  (' SMURF1%0'  ' GRB2%0')  (' SMURF1%0'  ' TGFBR1%0')  (' SMURF1%0'  ' SMURF2%0')  (' SMURF1%0'  ' RHOA%0')  (' SMURF1%0'  ' BMPR2%0')  (' SMURF1%0'  ' PARD6A%0')  (' SMURF1%0'  ' DAAM1%0')  (' SMURF1%0'  ' SFRP1_g%0')  (' SMURF1%0'  ' PPM1A%0')  (' SMURF1%0'  ' CFL_f%0')  (' SMURF1%0'  ' PAK1%0')  (' SMURF1%0'  ' MAP3K11%0')  (' SMURF1%0'  ' MAP3K4%0')  (' SMURF1%0'  ' LIMK1%0')  (' SMURF1%0'  ' ROCK1%0')  (' SMURF1%0'  ' ITCH%0')  (' SMURF1%0'  ' ARHGAP24%0')  (' SMURF1%0'  ' TIAM1%0')  (' SMURF1%0'  ' RND3%0')  (' SMURF1%0'  ' MAPK8IP3%0')  (' SMURF1%0'  ' MXD1%0')  (' SMURF1%0'  ' PIP3%0')  (' SMURF2%0'  ' SRC%0')  (' SMURF2%0'  ' CSK%0')  (' SMURF2%0'  ' CHUK%0')  (' SMURF2%0'  ' RAC_f%0')  (' SMURF2%0'  ' DUSP1%0')  (' SMURF2%0'  ' TGFBR2%0')  (' SMURF2%0'  ' ILR_f%0')  (' SMURF2%0'  ' SYK%0')  (' SMURF2%0'  ' IRAK1%0')  (' SMURF2%0'  ' SHC1%0')  (' SMURF2%0'  ' JAK_f%0')  (' SMURF2%0'  ' CBPp300_c%0')  (' SMURF2%0'  ' SKP2%0')  (' SMURF2%0'  ' TP53%0')  (' SMURF2%0'  ' SMAD7%0')  (' SMURF2%0'  ' SMAD6%0')  (' SMURF2%0'  ' DKK_f%0')  (' SMURF2%0'  ' FOXO_f%0')  (' SMURF2%0'  ' TCF7_f%0')  (' SMURF2%0'  ' DKK_g%0')  (' SMURF2%0'  ' MYC%0')  (' SMURF2%0'  ' CCND1%0')  (' SMURF2%0'  ' EGR1%0')  (' SMURF2%0'  ' MMP_f%0')  (' SMURF2%0'  ' PTEN_g%0')  (' SMURF2%0'  ' RTPK_f%0')  (' SMURF2%0'  ' CTNNB1%0')  (' SMURF2%0'  'LEF1%0')  (' SMURF2%0'  'SFRP1%0')  (' SMURF2%0'  'FZD_f%0')  (' SMURF2%0'  ' CASP8%0')  (' SMURF2%0'  ' REL_f%0')  (' SMURF2%0'  ' NFKB_f%0')  (' SMURF2%0'  ' DVL_f%0')  (' SMURF2%0'  ' LRP_f%0')  (' SMURF2%0'  ' BTRC%0')  (' SMURF2%0'  ' CK1_f%0')  (' SMURF2%0'  ' AXIN1%0')  (' SMURF2%0'  ' mTORC2_c%0')  (' SMURF2%0'  ' PDPK1%0')  (' SMURF2%0'  ' MEK_f%0')  (' SMURF2%0'  ' CYCS%0')  (' SMURF2%0'  ' CASP9%0')  (' SMURF2%0'  ' GSK3_f%0')  (' SMURF2%0'  ' IRS1%0')  (' SMURF2%0'  ' MDM2%0')  (' SMURF2%0'  ' AKT_f%0')  (' SMURF2%0'  ' BCL2%0')  (' SMURF2%0'  ' RAF_f%0')  (' SMURF2%0'  ' mTORC1_c%0')  (' SMURF2%0'  ' RHEB%0')  (' SMURF2%0'  ' RTPK_g%0')  (' SMURF2%0'  ' PTEN%0')  (' SMURF2%0'  ' CASP3%0')  (' SMURF2%0'  ' PIK3CA%0')  (' SMURF2%0'  ' CREBBP%0')  (' SMURF2%0'  ' PTPN11%0')  (' SMURF2%0'  ' KRAS%0')  (' SMURF2%0'  ' MAP2K4%0')  (' SMURF2%0'  ' MAP2K7%0')  (' SMURF2%0'  ' MAPK14%0')  (' SMURF2%0'  ' JNK_f%0')  (' SMURF2%0'  ' MAP2K3%0')  (' SMURF2%0'  ' ERK_f%0')  (' SMURF2%0'  ' LIF%0')  (' SMURF2%0'  ' PPP1CA%0')  (' SMURF2%0'  ' GAB_f%0')  (' SMURF2%0'  ' SOS1%0')  (' SMURF2%0'  ' PRKCA%0')  (' SMURF2%0'  ' VAV1%0')  (' SMURF2%0'  ' PLCG1%0')  (' SMURF2%0'  ' PRKCD%0')  (' SMURF2%0'  ' RSK_f%0')  (' SMURF2%0'  ' S6K_f%0')  (' SMURF2%0'  ' PLK1%0')  (' SMURF2%0'  ' ILK%0')  (' SMURF2%0'  ' SOCS1%0')  (' SMURF2%0'  ' DUSP6%0')  (' SMURF2%0'  ' STAT3%0')  (' SMURF2%0'  ' LIMK2%0')  (' SMURF2%0'  ' EP300%0')  (' SMURF2%0'  ' STAT1%0')  (' SMURF2%0'  ' IKBKB%0')  (' SMURF2%0'  ' SRF%0')  (' SMURF2%0'  ' PIAS1%0')  (' SMURF2%0'  ' TRAF6%0')  (' SMURF2%0'  ' SOCS1_g%0')  (' SMURF2%0'  ' ISGF3_c%0')  (' SMURF2%0'  ' STAT2%0')  (' SMURF2%0'  ' CFLAR%0')  (' SMURF2%0'  ' SMAD2%0')  (' SMURF2%0'  ' MDM2_g%0')  (' SMURF2%0'  ' BAX%0')  (' SMURF2%0'  ' PRKACA%0')  (' SMURF2%0'  ' TGFB1%0')  (' SMURF2%0'  ' MAP3K8%0')  (' SMURF2%0'  ' TSC_f%0')  (' SMURF2%0'  ' SMAD4%0')  (' SMURF2%0'  ' BAD%0')  (' SMURF2%0'  ' MAP3K5%0')  (' SMURF2%0'  ' AKT1S1%0')  (' SMURF2%0'  ' SKI%0')  (' SMURF2%0'  ' SMAD3%0')  (' SMURF2%0'  ' MAPKAPK2%0')  (' SMURF2%0'  ' DUSP1_g%0')  (' SMURF2%0'  ' MSK_f%0')  (' SMURF2%0'  ' GRAP2%0')  (' SMURF2%0'  ' TAB_f%0')  (' SMURF2%0'  ' ATF2%0')  (' SMURF2%0'  ' SMAD5%0')  (' SMURF2%0'  ' SMAD1%0')  (' SMURF2%0'  ' FOS%0')  (' SMURF2%0'  ' JUN%0')  (' SMURF2%0'  ' MAP3K7%0')  (' SMURF2%0'  ' NLK%0')  (' SMURF2%0'  ' SMAD7_g%0')  (' SMURF2%0'  ' SMAD6_g%0')  (' SMURF2%0'  ' AP1_c%0')  (' SMURF2%0'  ' ACVR1%0')  (' SMURF2%0'  ' PTPN6%0')  (' SMURF2%0'  ' CDC42%0')  (' SMURF2%0'  ' GRB2%0')  (' SMURF2%0'  ' TGFBR1%0')  (' SMURF2%0'  ' SMURF1%0')  (' SMURF2%0'  ' RHOA%0')  (' SMURF2%0'  ' BMPR2%0')  (' SMURF2%0'  ' PARD6A%0')  (' SMURF2%0'  ' DAAM1%0')  (' SMURF2%0'  ' SFRP1_g%0')  (' SMURF2%0'  ' PPM1A%0')  (' SMURF2%0'  ' CFL_f%0')  (' SMURF2%0'  ' PAK1%0')  (' SMURF2%0'  ' MAP3K11%0')  (' SMURF2%0'  ' MAP3K4%0')  (' SMURF2%0'  ' LIMK1%0')  (' SMURF2%0'  ' ROCK1%0')  (' SMURF2%0'  ' ITCH%0')  (' SMURF2%0'  ' ARHGAP24%0')  (' SMURF2%0'  ' TIAM1%0')  (' SMURF2%0'  ' RND3%0')  (' SMURF2%0'  ' MAPK8IP3%0')  (' SMURF2%0'  ' MXD1%0')  (' SMURF2%0'  ' PIP3%0')  (' RHOA%0'  ' SRC%0')  (' RHOA%0'  ' CSK%0')  (' RHOA%0'  ' CHUK%0')  (' RHOA%0'  ' RAC_f%0')  (' RHOA%0'  ' DUSP1%0')  (' RHOA%0'  ' TGFBR2%0')  (' RHOA%0'  ' ILR_f%0')  (' RHOA%0'  ' SYK%0')  (' RHOA%0'  ' IRAK1%0')  (' RHOA%0'  ' SHC1%0')  (' RHOA%0'  ' JAK_f%0')  (' RHOA%0'  ' CBPp300_c%0')  (' RHOA%0'  ' SKP2%0')  (' RHOA%0'  ' TP53%0')  (' RHOA%0'  ' SMAD7%0')  (' RHOA%0'  ' SMAD6%0')  (' RHOA%0'  ' DKK_f%0')  (' RHOA%0'  ' FOXO_f%0')  (' RHOA%0'  ' TCF7_f%0')  (' RHOA%0'  ' DKK_g%0')  (' RHOA%0'  ' MYC%0')  (' RHOA%0'  ' CCND1%0')  (' RHOA%0'  ' EGR1%0')  (' RHOA%0'  ' MMP_f%0')  (' RHOA%0'  ' PTEN_g%0')  (' RHOA%0'  ' RTPK_f%0')  (' RHOA%0'  ' CTNNB1%0')  (' RHOA%0'  'LEF1%0')  (' RHOA%0'  'SFRP1%0')  (' RHOA%0'  'FZD_f%0')  (' RHOA%0'  ' CASP8%0')  (' RHOA%0'  ' REL_f%0')  (' RHOA%0'  ' NFKB_f%0')  (' RHOA%0'  ' DVL_f%0')  (' RHOA%0'  ' LRP_f%0')  (' RHOA%0'  ' BTRC%0')  (' RHOA%0'  ' CK1_f%0')  (' RHOA%0'  ' AXIN1%0')  (' RHOA%0'  ' mTORC2_c%0')  (' RHOA%0'  ' PDPK1%0')  (' RHOA%0'  ' MEK_f%0')  (' RHOA%0'  ' CYCS%0')  (' RHOA%0'  ' CASP9%0')  (' RHOA%0'  ' GSK3_f%0')  (' RHOA%0'  ' IRS1%0')  (' RHOA%0'  ' MDM2%0')  (' RHOA%0'  ' AKT_f%0')  (' RHOA%0'  ' BCL2%0')  (' RHOA%0'  ' RAF_f%0')  (' RHOA%0'  ' mTORC1_c%0')  (' RHOA%0'  ' RHEB%0')  (' RHOA%0'  ' RTPK_g%0')  (' RHOA%0'  ' PTEN%0')  (' RHOA%0'  ' CASP3%0')  (' RHOA%0'  ' PIK3CA%0')  (' RHOA%0'  ' CREBBP%0')  (' RHOA%0'  ' PTPN11%0')  (' RHOA%0'  ' KRAS%0')  (' RHOA%0'  ' MAP2K4%0')  (' RHOA%0'  ' MAP2K7%0')  (' RHOA%0'  ' MAPK14%0')  (' RHOA%0'  ' JNK_f%0')  (' RHOA%0'  ' MAP2K3%0')  (' RHOA%0'  ' ERK_f%0')  (' RHOA%0'  ' LIF%0')  (' RHOA%0'  ' PPP1CA%0')  (' RHOA%0'  ' GAB_f%0')  (' RHOA%0'  ' SOS1%0')  (' RHOA%0'  ' PRKCA%0')  (' RHOA%0'  ' VAV1%0')  (' RHOA%0'  ' PLCG1%0')  (' RHOA%0'  ' PRKCD%0')  (' RHOA%0'  ' RSK_f%0')  (' RHOA%0'  ' S6K_f%0')  (' RHOA%0'  ' PLK1%0')  (' RHOA%0'  ' ILK%0')  (' RHOA%0'  ' SOCS1%0')  (' RHOA%0'  ' DUSP6%0')  (' RHOA%0'  ' STAT3%0')  (' RHOA%0'  ' LIMK2%0')  (' RHOA%0'  ' EP300%0')  (' RHOA%0'  ' STAT1%0')  (' RHOA%0'  ' IKBKB%0')  (' RHOA%0'  ' SRF%0')  (' RHOA%0'  ' PIAS1%0')  (' RHOA%0'  ' TRAF6%0')  (' RHOA%0'  ' SOCS1_g%0')  (' RHOA%0'  ' ISGF3_c%0')  (' RHOA%0'  ' STAT2%0')  (' RHOA%0'  ' CFLAR%0')  (' RHOA%0'  ' SMAD2%0')  (' RHOA%0'  ' MDM2_g%0')  (' RHOA%0'  ' BAX%0')  (' RHOA%0'  ' PRKACA%0')  (' RHOA%0'  ' TGFB1%0')  (' RHOA%0'  ' MAP3K8%0')  (' RHOA%0'  ' TSC_f%0')  (' RHOA%0'  ' SMAD4%0')  (' RHOA%0'  ' BAD%0')  (' RHOA%0'  ' MAP3K5%0')  (' RHOA%0'  ' AKT1S1%0')  (' RHOA%0'  ' SKI%0')  (' RHOA%0'  ' SMAD3%0')  (' RHOA%0'  ' MAPKAPK2%0')  (' RHOA%0'  ' DUSP1_g%0')  (' RHOA%0'  ' MSK_f%0')  (' RHOA%0'  ' GRAP2%0')  (' RHOA%0'  ' TAB_f%0')  (' RHOA%0'  ' ATF2%0')  (' RHOA%0'  ' SMAD5%0')  (' RHOA%0'  ' SMAD1%0')  (' RHOA%0'  ' FOS%0')  (' RHOA%0'  ' JUN%0')  (' RHOA%0'  ' MAP3K7%0')  (' RHOA%0'  ' NLK%0')  (' RHOA%0'  ' SMAD7_g%0')  (' RHOA%0'  ' SMAD6_g%0')  (' RHOA%0'  ' AP1_c%0')  (' RHOA%0'  ' ACVR1%0')  (' RHOA%0'  ' PTPN6%0')  (' RHOA%0'  ' CDC42%0')  (' RHOA%0'  ' GRB2%0')  (' RHOA%0'  ' TGFBR1%0')  (' RHOA%0'  ' SMURF1%0')  (' RHOA%0'  ' SMURF2%0')  (' RHOA%0'  ' BMPR2%0')  (' RHOA%0'  ' PARD6A%0')  (' RHOA%0'  ' DAAM1%0')  (' RHOA%0'  ' SFRP1_g%0')  (' RHOA%0'  ' PPM1A%0')  (' RHOA%0'  ' CFL_f%0')  (' RHOA%0'  ' PAK1%0')  (' RHOA%0'  ' MAP3K11%0')  (' RHOA%0'  ' MAP3K4%0')  (' RHOA%0'  ' LIMK1%0')  (' RHOA%0'  ' ROCK1%0')  (' RHOA%0'  ' ITCH%0')  (' RHOA%0'  ' ARHGAP24%0')  (' RHOA%0'  ' TIAM1%0')  (' RHOA%0'  ' RND3%0')  (' RHOA%0'  ' MAPK8IP3%0')  (' RHOA%0'  ' MXD1%0')  (' RHOA%0'  ' PIP3%0')  (' BMPR2%0'  ' SRC%0')  (' BMPR2%0'  ' CSK%0')  (' BMPR2%0'  ' CHUK%0')  (' BMPR2%0'  ' RAC_f%0')  (' BMPR2%0'  ' DUSP1%0')  (' BMPR2%0'  ' TGFBR2%0')  (' BMPR2%0'  ' ILR_f%0')  (' BMPR2%0'  ' SYK%0')  (' BMPR2%0'  ' IRAK1%0')  (' BMPR2%0'  ' SHC1%0')  (' BMPR2%0'  ' JAK_f%0')  (' BMPR2%0'  ' CBPp300_c%0')  (' BMPR2%0'  ' SKP2%0')  (' BMPR2%0'  ' TP53%0')  (' BMPR2%0'  ' SMAD7%0')  (' BMPR2%0'  ' SMAD6%0')  (' BMPR2%0'  ' DKK_f%0')  (' BMPR2%0'  ' FOXO_f%0')  (' BMPR2%0'  ' TCF7_f%0')  (' BMPR2%0'  ' DKK_g%0')  (' BMPR2%0'  ' MYC%0')  (' BMPR2%0'  ' CCND1%0')  (' BMPR2%0'  ' EGR1%0')  (' BMPR2%0'  ' MMP_f%0')  (' BMPR2%0'  ' PTEN_g%0')  (' BMPR2%0'  ' RTPK_f%0')  (' BMPR2%0'  ' CTNNB1%0')  (' BMPR2%0'  'LEF1%0')  (' BMPR2%0'  'SFRP1%0')  (' BMPR2%0'  'FZD_f%0')  (' BMPR2%0'  ' CASP8%0')  (' BMPR2%0'  ' REL_f%0')  (' BMPR2%0'  ' NFKB_f%0')  (' BMPR2%0'  ' DVL_f%0')  (' BMPR2%0'  ' LRP_f%0')  (' BMPR2%0'  ' BTRC%0')  (' BMPR2%0'  ' CK1_f%0')  (' BMPR2%0'  ' AXIN1%0')  (' BMPR2%0'  ' mTORC2_c%0')  (' BMPR2%0'  ' PDPK1%0')  (' BMPR2%0'  ' MEK_f%0')  (' BMPR2%0'  ' CYCS%0')  (' BMPR2%0'  ' CASP9%0')  (' BMPR2%0'  ' GSK3_f%0')  (' BMPR2%0'  ' IRS1%0')  (' BMPR2%0'  ' MDM2%0')  (' BMPR2%0'  ' AKT_f%0')  (' BMPR2%0'  ' BCL2%0')  (' BMPR2%0'  ' RAF_f%0')  (' BMPR2%0'  ' mTORC1_c%0')  (' BMPR2%0'  ' RHEB%0')  (' BMPR2%0'  ' RTPK_g%0')  (' BMPR2%0'  ' PTEN%0')  (' BMPR2%0'  ' CASP3%0')  (' BMPR2%0'  ' PIK3CA%0')  (' BMPR2%0'  ' CREBBP%0')  (' BMPR2%0'  ' PTPN11%0')  (' BMPR2%0'  ' KRAS%0')  (' BMPR2%0'  ' MAP2K4%0')  (' BMPR2%0'  ' MAP2K7%0')  (' BMPR2%0'  ' MAPK14%0')  (' BMPR2%0'  ' JNK_f%0')  (' BMPR2%0'  ' MAP2K3%0')  (' BMPR2%0'  ' ERK_f%0')  (' BMPR2%0'  ' LIF%0')  (' BMPR2%0'  ' PPP1CA%0')  (' BMPR2%0'  ' GAB_f%0')  (' BMPR2%0'  ' SOS1%0')  (' BMPR2%0'  ' PRKCA%0')  (' BMPR2%0'  ' VAV1%0')  (' BMPR2%0'  ' PLCG1%0')  (' BMPR2%0'  ' PRKCD%0')  (' BMPR2%0'  ' RSK_f%0')  (' BMPR2%0'  ' S6K_f%0')  (' BMPR2%0'  ' PLK1%0')  (' BMPR2%0'  ' ILK%0')  (' BMPR2%0'  ' SOCS1%0')  (' BMPR2%0'  ' DUSP6%0')  (' BMPR2%0'  ' STAT3%0')  (' BMPR2%0'  ' LIMK2%0')  (' BMPR2%0'  ' EP300%0')  (' BMPR2%0'  ' STAT1%0')  (' BMPR2%0'  ' IKBKB%0')  (' BMPR2%0'  ' SRF%0')  (' BMPR2%0'  ' PIAS1%0')  (' BMPR2%0'  ' TRAF6%0')  (' BMPR2%0'  ' SOCS1_g%0')  (' BMPR2%0'  ' ISGF3_c%0')  (' BMPR2%0'  ' STAT2%0')  (' BMPR2%0'  ' CFLAR%0')  (' BMPR2%0'  ' SMAD2%0')  (' BMPR2%0'  ' MDM2_g%0')  (' BMPR2%0'  ' BAX%0')  (' BMPR2%0'  ' PRKACA%0')  (' BMPR2%0'  ' TGFB1%0')  (' BMPR2%0'  ' MAP3K8%0')  (' BMPR2%0'  ' TSC_f%0')  (' BMPR2%0'  ' SMAD4%0')  (' BMPR2%0'  ' BAD%0')  (' BMPR2%0'  ' MAP3K5%0')  (' BMPR2%0'  ' AKT1S1%0')  (' BMPR2%0'  ' SKI%0')  (' BMPR2%0'  ' SMAD3%0')  (' BMPR2%0'  ' MAPKAPK2%0')  (' BMPR2%0'  ' DUSP1_g%0')  (' BMPR2%0'  ' MSK_f%0')  (' BMPR2%0'  ' GRAP2%0')  (' BMPR2%0'  ' TAB_f%0')  (' BMPR2%0'  ' ATF2%0')  (' BMPR2%0'  ' SMAD5%0')  (' BMPR2%0'  ' SMAD1%0')  (' BMPR2%0'  ' FOS%0')  (' BMPR2%0'  ' JUN%0')  (' BMPR2%0'  ' MAP3K7%0')  (' BMPR2%0'  ' NLK%0')  (' BMPR2%0'  ' SMAD7_g%0')  (' BMPR2%0'  ' SMAD6_g%0')  (' BMPR2%0'  ' AP1_c%0')  (' BMPR2%0'  ' ACVR1%0')  (' BMPR2%0'  ' PTPN6%0')  (' BMPR2%0'  ' CDC42%0')  (' BMPR2%0'  ' GRB2%0')  (' BMPR2%0'  ' TGFBR1%0')  (' BMPR2%0'  ' SMURF1%0')  (' BMPR2%0'  ' SMURF2%0')  (' BMPR2%0'  ' RHOA%0')  (' BMPR2%0'  ' PARD6A%0')  (' BMPR2%0'  ' DAAM1%0')  (' BMPR2%0'  ' SFRP1_g%0')  (' BMPR2%0'  ' PPM1A%0')  (' BMPR2%0'  ' CFL_f%0')  (' BMPR2%0'  ' PAK1%0')  (' BMPR2%0'  ' MAP3K11%0')  (' BMPR2%0'  ' MAP3K4%0')  (' BMPR2%0'  ' LIMK1%0')  (' BMPR2%0'  ' ROCK1%0')  (' BMPR2%0'  ' ITCH%0')  (' BMPR2%0'  ' ARHGAP24%0')  (' BMPR2%0'  ' TIAM1%0')  (' BMPR2%0'  ' RND3%0')  (' BMPR2%0'  ' MAPK8IP3%0')  (' BMPR2%0'  ' MXD1%0')  (' BMPR2%0'  ' PIP3%0')  (' PARD6A%0'  ' SRC%0')  (' PARD6A%0'  ' CSK%0')  (' PARD6A%0'  ' CHUK%0')  (' PARD6A%0'  ' RAC_f%0')  (' PARD6A%0'  ' DUSP1%0')  (' PARD6A%0'  ' TGFBR2%0')  (' PARD6A%0'  ' ILR_f%0')  (' PARD6A%0'  ' SYK%0')  (' PARD6A%0'  ' IRAK1%0')  (' PARD6A%0'  ' SHC1%0')  (' PARD6A%0'  ' JAK_f%0')  (' PARD6A%0'  ' CBPp300_c%0')  (' PARD6A%0'  ' SKP2%0')  (' PARD6A%0'  ' TP53%0')  (' PARD6A%0'  ' SMAD7%0')  (' PARD6A%0'  ' SMAD6%0')  (' PARD6A%0'  ' DKK_f%0')  (' PARD6A%0'  ' FOXO_f%0')  (' PARD6A%0'  ' TCF7_f%0')  (' PARD6A%0'  ' DKK_g%0')  (' PARD6A%0'  ' MYC%0')  (' PARD6A%0'  ' CCND1%0')  (' PARD6A%0'  ' EGR1%0')  (' PARD6A%0'  ' MMP_f%0')  (' PARD6A%0'  ' PTEN_g%0')  (' PARD6A%0'  ' RTPK_f%0')  (' PARD6A%0'  ' CTNNB1%0')  (' PARD6A%0'  'LEF1%0')  (' PARD6A%0'  'SFRP1%0')  (' PARD6A%0'  'FZD_f%0')  (' PARD6A%0'  ' CASP8%0')  (' PARD6A%0'  ' REL_f%0')  (' PARD6A%0'  ' NFKB_f%0')  (' PARD6A%0'  ' DVL_f%0')  (' PARD6A%0'  ' LRP_f%0')  (' PARD6A%0'  ' BTRC%0')  (' PARD6A%0'  ' CK1_f%0')  (' PARD6A%0'  ' AXIN1%0')  (' PARD6A%0'  ' mTORC2_c%0')  (' PARD6A%0'  ' PDPK1%0')  (' PARD6A%0'  ' MEK_f%0')  (' PARD6A%0'  ' CYCS%0')  (' PARD6A%0'  ' CASP9%0')  (' PARD6A%0'  ' GSK3_f%0')  (' PARD6A%0'  ' IRS1%0')  (' PARD6A%0'  ' MDM2%0')  (' PARD6A%0'  ' AKT_f%0')  (' PARD6A%0'  ' BCL2%0')  (' PARD6A%0'  ' RAF_f%0')  (' PARD6A%0'  ' mTORC1_c%0')  (' PARD6A%0'  ' RHEB%0')  (' PARD6A%0'  ' RTPK_g%0')  (' PARD6A%0'  ' PTEN%0')  (' PARD6A%0'  ' CASP3%0')  (' PARD6A%0'  ' PIK3CA%0')  (' PARD6A%0'  ' CREBBP%0')  (' PARD6A%0'  ' PTPN11%0')  (' PARD6A%0'  ' KRAS%0')  (' PARD6A%0'  ' MAP2K4%0')  (' PARD6A%0'  ' MAP2K7%0')  (' PARD6A%0'  ' MAPK14%0')  (' PARD6A%0'  ' JNK_f%0')  (' PARD6A%0'  ' MAP2K3%0')  (' PARD6A%0'  ' ERK_f%0')  (' PARD6A%0'  ' LIF%0')  (' PARD6A%0'  ' PPP1CA%0')  (' PARD6A%0'  ' GAB_f%0')  (' PARD6A%0'  ' SOS1%0')  (' PARD6A%0'  ' PRKCA%0')  (' PARD6A%0'  ' VAV1%0')  (' PARD6A%0'  ' PLCG1%0')  (' PARD6A%0'  ' PRKCD%0')  (' PARD6A%0'  ' RSK_f%0')  (' PARD6A%0'  ' S6K_f%0')  (' PARD6A%0'  ' PLK1%0')  (' PARD6A%0'  ' ILK%0')  (' PARD6A%0'  ' SOCS1%0')  (' PARD6A%0'  ' DUSP6%0')  (' PARD6A%0'  ' STAT3%0')  (' PARD6A%0'  ' LIMK2%0')  (' PARD6A%0'  ' EP300%0')  (' PARD6A%0'  ' STAT1%0')  (' PARD6A%0'  ' IKBKB%0')  (' PARD6A%0'  ' SRF%0')  (' PARD6A%0'  ' PIAS1%0')  (' PARD6A%0'  ' TRAF6%0')  (' PARD6A%0'  ' SOCS1_g%0')  (' PARD6A%0'  ' ISGF3_c%0')  (' PARD6A%0'  ' STAT2%0')  (' PARD6A%0'  ' CFLAR%0')  (' PARD6A%0'  ' SMAD2%0')  (' PARD6A%0'  ' MDM2_g%0')  (' PARD6A%0'  ' BAX%0')  (' PARD6A%0'  ' PRKACA%0')  (' PARD6A%0'  ' TGFB1%0')  (' PARD6A%0'  ' MAP3K8%0')  (' PARD6A%0'  ' TSC_f%0')  (' PARD6A%0'  ' SMAD4%0')  (' PARD6A%0'  ' BAD%0')  (' PARD6A%0'  ' MAP3K5%0')  (' PARD6A%0'  ' AKT1S1%0')  (' PARD6A%0'  ' SKI%0')  (' PARD6A%0'  ' SMAD3%0')  (' PARD6A%0'  ' MAPKAPK2%0')  (' PARD6A%0'  ' DUSP1_g%0')  (' PARD6A%0'  ' MSK_f%0')  (' PARD6A%0'  ' GRAP2%0')  (' PARD6A%0'  ' TAB_f%0')  (' PARD6A%0'  ' ATF2%0')  (' PARD6A%0'  ' SMAD5%0')  (' PARD6A%0'  ' SMAD1%0')  (' PARD6A%0'  ' FOS%0')  (' PARD6A%0'  ' JUN%0')  (' PARD6A%0'  ' MAP3K7%0')  (' PARD6A%0'  ' NLK%0')  (' PARD6A%0'  ' SMAD7_g%0')  (' PARD6A%0'  ' SMAD6_g%0')  (' PARD6A%0'  ' AP1_c%0')  (' PARD6A%0'  ' ACVR1%0')  (' PARD6A%0'  ' PTPN6%0')  (' PARD6A%0'  ' CDC42%0')  (' PARD6A%0'  ' GRB2%0')  (' PARD6A%0'  ' TGFBR1%0')  (' PARD6A%0'  ' SMURF1%0')  (' PARD6A%0'  ' SMURF2%0')  (' PARD6A%0'  ' RHOA%0')  (' PARD6A%0'  ' BMPR2%0')  (' PARD6A%0'  ' DAAM1%0')  (' PARD6A%0'  ' SFRP1_g%0')  (' PARD6A%0'  ' PPM1A%0')  (' PARD6A%0'  ' CFL_f%0')  (' PARD6A%0'  ' PAK1%0')  (' PARD6A%0'  ' MAP3K11%0')  (' PARD6A%0'  ' MAP3K4%0')  (' PARD6A%0'  ' LIMK1%0')  (' PARD6A%0'  ' ROCK1%0')  (' PARD6A%0'  ' ITCH%0')  (' PARD6A%0'  ' ARHGAP24%0')  (' PARD6A%0'  ' TIAM1%0')  (' PARD6A%0'  ' RND3%0')  (' PARD6A%0'  ' MAPK8IP3%0')  (' PARD6A%0'  ' MXD1%0')  (' PARD6A%0'  ' PIP3%0')  (' DAAM1%0'  ' SRC%0')  (' DAAM1%0'  ' CSK%0')  (' DAAM1%0'  ' CHUK%0')  (' DAAM1%0'  ' RAC_f%0')  (' DAAM1%0'  ' DUSP1%0')  (' DAAM1%0'  ' TGFBR2%0')  (' DAAM1%0'  ' ILR_f%0')  (' DAAM1%0'  ' SYK%0')  (' DAAM1%0'  ' IRAK1%0')  (' DAAM1%0'  ' SHC1%0')  (' DAAM1%0'  ' JAK_f%0')  (' DAAM1%0'  ' CBPp300_c%0')  (' DAAM1%0'  ' SKP2%0')  (' DAAM1%0'  ' TP53%0')  (' DAAM1%0'  ' SMAD7%0')  (' DAAM1%0'  ' SMAD6%0')  (' DAAM1%0'  ' DKK_f%0')  (' DAAM1%0'  ' FOXO_f%0')  (' DAAM1%0'  ' TCF7_f%0')  (' DAAM1%0'  ' DKK_g%0')  (' DAAM1%0'  ' MYC%0')  (' DAAM1%0'  ' CCND1%0')  (' DAAM1%0'  ' EGR1%0')  (' DAAM1%0'  ' MMP_f%0')  (' DAAM1%0'  ' PTEN_g%0')  (' DAAM1%0'  ' RTPK_f%0')  (' DAAM1%0'  ' CTNNB1%0')  (' DAAM1%0'  'LEF1%0')  (' DAAM1%0'  'SFRP1%0')  (' DAAM1%0'  'FZD_f%0')  (' DAAM1%0'  ' CASP8%0')  (' DAAM1%0'  ' REL_f%0')  (' DAAM1%0'  ' NFKB_f%0')  (' DAAM1%0'  ' DVL_f%0')  (' DAAM1%0'  ' LRP_f%0')  (' DAAM1%0'  ' BTRC%0')  (' DAAM1%0'  ' CK1_f%0')  (' DAAM1%0'  ' AXIN1%0')  (' DAAM1%0'  ' mTORC2_c%0')  (' DAAM1%0'  ' PDPK1%0')  (' DAAM1%0'  ' MEK_f%0')  (' DAAM1%0'  ' CYCS%0')  (' DAAM1%0'  ' CASP9%0')  (' DAAM1%0'  ' GSK3_f%0')  (' DAAM1%0'  ' IRS1%0')  (' DAAM1%0'  ' MDM2%0')  (' DAAM1%0'  ' AKT_f%0')  (' DAAM1%0'  ' BCL2%0')  (' DAAM1%0'  ' RAF_f%0')  (' DAAM1%0'  ' mTORC1_c%0')  (' DAAM1%0'  ' RHEB%0')  (' DAAM1%0'  ' RTPK_g%0')  (' DAAM1%0'  ' PTEN%0')  (' DAAM1%0'  ' CASP3%0')  (' DAAM1%0'  ' PIK3CA%0')  (' DAAM1%0'  ' CREBBP%0')  (' DAAM1%0'  ' PTPN11%0')  (' DAAM1%0'  ' KRAS%0')  (' DAAM1%0'  ' MAP2K4%0')  (' DAAM1%0'  ' MAP2K7%0')  (' DAAM1%0'  ' MAPK14%0')  (' DAAM1%0'  ' JNK_f%0')  (' DAAM1%0'  ' MAP2K3%0')  (' DAAM1%0'  ' ERK_f%0')  (' DAAM1%0'  ' LIF%0')  (' DAAM1%0'  ' PPP1CA%0')  (' DAAM1%0'  ' GAB_f%0')  (' DAAM1%0'  ' SOS1%0')  (' DAAM1%0'  ' PRKCA%0')  (' DAAM1%0'  ' VAV1%0')  (' DAAM1%0'  ' PLCG1%0')  (' DAAM1%0'  ' PRKCD%0')  (' DAAM1%0'  ' RSK_f%0')  (' DAAM1%0'  ' S6K_f%0')  (' DAAM1%0'  ' PLK1%0')  (' DAAM1%0'  ' ILK%0')  (' DAAM1%0'  ' SOCS1%0')  (' DAAM1%0'  ' DUSP6%0')  (' DAAM1%0'  ' STAT3%0')  (' DAAM1%0'  ' LIMK2%0')  (' DAAM1%0'  ' EP300%0')  (' DAAM1%0'  ' STAT1%0')  (' DAAM1%0'  ' IKBKB%0')  (' DAAM1%0'  ' SRF%0')  (' DAAM1%0'  ' PIAS1%0')  (' DAAM1%0'  ' TRAF6%0')  (' DAAM1%0'  ' SOCS1_g%0')  (' DAAM1%0'  ' ISGF3_c%0')  (' DAAM1%0'  ' STAT2%0')  (' DAAM1%0'  ' CFLAR%0')  (' DAAM1%0'  ' SMAD2%0')  (' DAAM1%0'  ' MDM2_g%0')  (' DAAM1%0'  ' BAX%0')  (' DAAM1%0'  ' PRKACA%0')  (' DAAM1%0'  ' TGFB1%0')  (' DAAM1%0'  ' MAP3K8%0')  (' DAAM1%0'  ' TSC_f%0')  (' DAAM1%0'  ' SMAD4%0')  (' DAAM1%0'  ' BAD%0')  (' DAAM1%0'  ' MAP3K5%0')  (' DAAM1%0'  ' AKT1S1%0')  (' DAAM1%0'  ' SKI%0')  (' DAAM1%0'  ' SMAD3%0')  (' DAAM1%0'  ' MAPKAPK2%0')  (' DAAM1%0'  ' DUSP1_g%0')  (' DAAM1%0'  ' MSK_f%0')  (' DAAM1%0'  ' GRAP2%0')  (' DAAM1%0'  ' TAB_f%0')  (' DAAM1%0'  ' ATF2%0')  (' DAAM1%0'  ' SMAD5%0')  (' DAAM1%0'  ' SMAD1%0')  (' DAAM1%0'  ' FOS%0')  (' DAAM1%0'  ' JUN%0')  (' DAAM1%0'  ' MAP3K7%0')  (' DAAM1%0'  ' NLK%0')  (' DAAM1%0'  ' SMAD7_g%0')  (' DAAM1%0'  ' SMAD6_g%0')  (' DAAM1%0'  ' AP1_c%0')  (' DAAM1%0'  ' ACVR1%0')  (' DAAM1%0'  ' PTPN6%0')  (' DAAM1%0'  ' CDC42%0')  (' DAAM1%0'  ' GRB2%0')  (' DAAM1%0'  ' TGFBR1%0')  (' DAAM1%0'  ' SMURF1%0')  (' DAAM1%0'  ' SMURF2%0')  (' DAAM1%0'  ' RHOA%0')  (' DAAM1%0'  ' BMPR2%0')  (' DAAM1%0'  ' PARD6A%0')  (' DAAM1%0'  ' SFRP1_g%0')  (' DAAM1%0'  ' PPM1A%0')  (' DAAM1%0'  ' CFL_f%0')  (' DAAM1%0'  ' PAK1%0')  (' DAAM1%0'  ' MAP3K11%0')  (' DAAM1%0'  ' MAP3K4%0')  (' DAAM1%0'  ' LIMK1%0')  (' DAAM1%0'  ' ROCK1%0')  (' DAAM1%0'  ' ITCH%0')  (' DAAM1%0'  ' ARHGAP24%0')  (' DAAM1%0'  ' TIAM1%0')  (' DAAM1%0'  ' RND3%0')  (' DAAM1%0'  ' MAPK8IP3%0')  (' DAAM1%0'  ' MXD1%0')  (' DAAM1%0'  ' PIP3%0')  (' SFRP1_g%0'  ' SRC%0')  (' SFRP1_g%0'  ' CSK%0')  (' SFRP1_g%0'  ' CHUK%0')  (' SFRP1_g%0'  ' RAC_f%0')  (' SFRP1_g%0'  ' DUSP1%0')  (' SFRP1_g%0'  ' TGFBR2%0')  (' SFRP1_g%0'  ' ILR_f%0')  (' SFRP1_g%0'  ' SYK%0')  (' SFRP1_g%0'  ' IRAK1%0')  (' SFRP1_g%0'  ' SHC1%0')  (' SFRP1_g%0'  ' JAK_f%0')  (' SFRP1_g%0'  ' CBPp300_c%0')  (' SFRP1_g%0'  ' SKP2%0')  (' SFRP1_g%0'  ' TP53%0')  (' SFRP1_g%0'  ' SMAD7%0')  (' SFRP1_g%0'  ' SMAD6%0')  (' SFRP1_g%0'  ' DKK_f%0')  (' SFRP1_g%0'  ' FOXO_f%0')  (' SFRP1_g%0'  ' TCF7_f%0')  (' SFRP1_g%0'  ' DKK_g%0')  (' SFRP1_g%0'  ' MYC%0')  (' SFRP1_g%0'  ' CCND1%0')  (' SFRP1_g%0'  ' EGR1%0')  (' SFRP1_g%0'  ' MMP_f%0')  (' SFRP1_g%0'  ' PTEN_g%0')  (' SFRP1_g%0'  ' RTPK_f%0')  (' SFRP1_g%0'  ' CTNNB1%0')  (' SFRP1_g%0'  'LEF1%0')  (' SFRP1_g%0'  'SFRP1%0')  (' SFRP1_g%0'  'FZD_f%0')  (' SFRP1_g%0'  ' CASP8%0')  (' SFRP1_g%0'  ' REL_f%0')  (' SFRP1_g%0'  ' NFKB_f%0')  (' SFRP1_g%0'  ' DVL_f%0')  (' SFRP1_g%0'  ' LRP_f%0')  (' SFRP1_g%0'  ' BTRC%0')  (' SFRP1_g%0'  ' CK1_f%0')  (' SFRP1_g%0'  ' AXIN1%0')  (' SFRP1_g%0'  ' mTORC2_c%0')  (' SFRP1_g%0'  ' PDPK1%0')  (' SFRP1_g%0'  ' MEK_f%0')  (' SFRP1_g%0'  ' CYCS%0')  (' SFRP1_g%0'  ' CASP9%0')  (' SFRP1_g%0'  ' GSK3_f%0')  (' SFRP1_g%0'  ' IRS1%0')  (' SFRP1_g%0'  ' MDM2%0')  (' SFRP1_g%0'  ' AKT_f%0')  (' SFRP1_g%0'  ' BCL2%0')  (' SFRP1_g%0'  ' RAF_f%0')  (' SFRP1_g%0'  ' mTORC1_c%0')  (' SFRP1_g%0'  ' RHEB%0')  (' SFRP1_g%0'  ' RTPK_g%0')  (' SFRP1_g%0'  ' PTEN%0')  (' SFRP1_g%0'  ' CASP3%0')  (' SFRP1_g%0'  ' PIK3CA%0')  (' SFRP1_g%0'  ' CREBBP%0')  (' SFRP1_g%0'  ' PTPN11%0')  (' SFRP1_g%0'  ' KRAS%0')  (' SFRP1_g%0'  ' MAP2K4%0')  (' SFRP1_g%0'  ' MAP2K7%0')  (' SFRP1_g%0'  ' MAPK14%0')  (' SFRP1_g%0'  ' JNK_f%0')  (' SFRP1_g%0'  ' MAP2K3%0')  (' SFRP1_g%0'  ' ERK_f%0')  (' SFRP1_g%0'  ' LIF%0')  (' SFRP1_g%0'  ' PPP1CA%0')  (' SFRP1_g%0'  ' GAB_f%0')  (' SFRP1_g%0'  ' SOS1%0')  (' SFRP1_g%0'  ' PRKCA%0')  (' SFRP1_g%0'  ' VAV1%0')  (' SFRP1_g%0'  ' PLCG1%0')  (' SFRP1_g%0'  ' PRKCD%0')  (' SFRP1_g%0'  ' RSK_f%0')  (' SFRP1_g%0'  ' S6K_f%0')  (' SFRP1_g%0'  ' PLK1%0')  (' SFRP1_g%0'  ' ILK%0')  (' SFRP1_g%0'  ' SOCS1%0')  (' SFRP1_g%0'  ' DUSP6%0')  (' SFRP1_g%0'  ' STAT3%0')  (' SFRP1_g%0'  ' LIMK2%0')  (' SFRP1_g%0'  ' EP300%0')  (' SFRP1_g%0'  ' STAT1%0')  (' SFRP1_g%0'  ' IKBKB%0')  (' SFRP1_g%0'  ' SRF%0')  (' SFRP1_g%0'  ' PIAS1%0')  (' SFRP1_g%0'  ' TRAF6%0')  (' SFRP1_g%0'  ' SOCS1_g%0')  (' SFRP1_g%0'  ' ISGF3_c%0')  (' SFRP1_g%0'  ' STAT2%0')  (' SFRP1_g%0'  ' CFLAR%0')  (' SFRP1_g%0'  ' SMAD2%0')  (' SFRP1_g%0'  ' MDM2_g%0')  (' SFRP1_g%0'  ' BAX%0')  (' SFRP1_g%0'  ' PRKACA%0')  (' SFRP1_g%0'  ' TGFB1%0')  (' SFRP1_g%0'  ' MAP3K8%0')  (' SFRP1_g%0'  ' TSC_f%0')  (' SFRP1_g%0'  ' SMAD4%0')  (' SFRP1_g%0'  ' BAD%0')  (' SFRP1_g%0'  ' MAP3K5%0')  (' SFRP1_g%0'  ' AKT1S1%0')  (' SFRP1_g%0'  ' SKI%0')  (' SFRP1_g%0'  ' SMAD3%0')  (' SFRP1_g%0'  ' MAPKAPK2%0')  (' SFRP1_g%0'  ' DUSP1_g%0')  (' SFRP1_g%0'  ' MSK_f%0')  (' SFRP1_g%0'  ' GRAP2%0')  (' SFRP1_g%0'  ' TAB_f%0')  (' SFRP1_g%0'  ' ATF2%0')  (' SFRP1_g%0'  ' SMAD5%0')  (' SFRP1_g%0'  ' SMAD1%0')  (' SFRP1_g%0'  ' FOS%0')  (' SFRP1_g%0'  ' JUN%0')  (' SFRP1_g%0'  ' MAP3K7%0')  (' SFRP1_g%0'  ' NLK%0')  (' SFRP1_g%0'  ' SMAD7_g%0')  (' SFRP1_g%0'  ' SMAD6_g%0')  (' SFRP1_g%0'  ' AP1_c%0')  (' SFRP1_g%0'  ' ACVR1%0')  (' SFRP1_g%0'  ' PTPN6%0')  (' SFRP1_g%0'  ' CDC42%0')  (' SFRP1_g%0'  ' GRB2%0')  (' SFRP1_g%0'  ' TGFBR1%0')  (' SFRP1_g%0'  ' SMURF1%0')  (' SFRP1_g%0'  ' SMURF2%0')  (' SFRP1_g%0'  ' RHOA%0')  (' SFRP1_g%0'  ' BMPR2%0')  (' SFRP1_g%0'  ' PARD6A%0')  (' SFRP1_g%0'  ' DAAM1%0')  (' SFRP1_g%0'  ' PPM1A%0')  (' SFRP1_g%0'  ' CFL_f%0')  (' SFRP1_g%0'  ' PAK1%0')  (' SFRP1_g%0'  ' MAP3K11%0')  (' SFRP1_g%0'  ' MAP3K4%0')  (' SFRP1_g%0'  ' LIMK1%0')  (' SFRP1_g%0'  ' ROCK1%0')  (' SFRP1_g%0'  ' ITCH%0')  (' SFRP1_g%0'  ' ARHGAP24%0')  (' SFRP1_g%0'  ' TIAM1%0')  (' SFRP1_g%0'  ' RND3%0')  (' SFRP1_g%0'  ' MAPK8IP3%0')  (' SFRP1_g%0'  ' MXD1%0')  (' SFRP1_g%0'  ' PIP3%0')  (' PPM1A%0'  ' SRC%0')  (' PPM1A%0'  ' CSK%0')  (' PPM1A%0'  ' CHUK%0')  (' PPM1A%0'  ' RAC_f%0')  (' PPM1A%0'  ' DUSP1%0')  (' PPM1A%0'  ' TGFBR2%0')  (' PPM1A%0'  ' ILR_f%0')  (' PPM1A%0'  ' SYK%0')  (' PPM1A%0'  ' IRAK1%0')  (' PPM1A%0'  ' SHC1%0')  (' PPM1A%0'  ' JAK_f%0')  (' PPM1A%0'  ' CBPp300_c%0')  (' PPM1A%0'  ' SKP2%0')  (' PPM1A%0'  ' TP53%0')  (' PPM1A%0'  ' SMAD7%0')  (' PPM1A%0'  ' SMAD6%0')  (' PPM1A%0'  ' DKK_f%0')  (' PPM1A%0'  ' FOXO_f%0')  (' PPM1A%0'  ' TCF7_f%0')  (' PPM1A%0'  ' DKK_g%0')  (' PPM1A%0'  ' MYC%0')  (' PPM1A%0'  ' CCND1%0')  (' PPM1A%0'  ' EGR1%0')  (' PPM1A%0'  ' MMP_f%0')  (' PPM1A%0'  ' PTEN_g%0')  (' PPM1A%0'  ' RTPK_f%0')  (' PPM1A%0'  ' CTNNB1%0')  (' PPM1A%0'  'LEF1%0')  (' PPM1A%0'  'SFRP1%0')  (' PPM1A%0'  'FZD_f%0')  (' PPM1A%0'  ' CASP8%0')  (' PPM1A%0'  ' REL_f%0')  (' PPM1A%0'  ' NFKB_f%0')  (' PPM1A%0'  ' DVL_f%0')  (' PPM1A%0'  ' LRP_f%0')  (' PPM1A%0'  ' BTRC%0')  (' PPM1A%0'  ' CK1_f%0')  (' PPM1A%0'  ' AXIN1%0')  (' PPM1A%0'  ' mTORC2_c%0')  (' PPM1A%0'  ' PDPK1%0')  (' PPM1A%0'  ' MEK_f%0')  (' PPM1A%0'  ' CYCS%0')  (' PPM1A%0'  ' CASP9%0')  (' PPM1A%0'  ' GSK3_f%0')  (' PPM1A%0'  ' IRS1%0')  (' PPM1A%0'  ' MDM2%0')  (' PPM1A%0'  ' AKT_f%0')  (' PPM1A%0'  ' BCL2%0')  (' PPM1A%0'  ' RAF_f%0')  (' PPM1A%0'  ' mTORC1_c%0')  (' PPM1A%0'  ' RHEB%0')  (' PPM1A%0'  ' RTPK_g%0')  (' PPM1A%0'  ' PTEN%0')  (' PPM1A%0'  ' CASP3%0')  (' PPM1A%0'  ' PIK3CA%0')  (' PPM1A%0'  ' CREBBP%0')  (' PPM1A%0'  ' PTPN11%0')  (' PPM1A%0'  ' KRAS%0')  (' PPM1A%0'  ' MAP2K4%0')  (' PPM1A%0'  ' MAP2K7%0')  (' PPM1A%0'  ' MAPK14%0')  (' PPM1A%0'  ' JNK_f%0')  (' PPM1A%0'  ' MAP2K3%0')  (' PPM1A%0'  ' ERK_f%0')  (' PPM1A%0'  ' LIF%0')  (' PPM1A%0'  ' PPP1CA%0')  (' PPM1A%0'  ' GAB_f%0')  (' PPM1A%0'  ' SOS1%0')  (' PPM1A%0'  ' PRKCA%0')  (' PPM1A%0'  ' VAV1%0')  (' PPM1A%0'  ' PLCG1%0')  (' PPM1A%0'  ' PRKCD%0')  (' PPM1A%0'  ' RSK_f%0')  (' PPM1A%0'  ' S6K_f%0')  (' PPM1A%0'  ' PLK1%0')  (' PPM1A%0'  ' ILK%0')  (' PPM1A%0'  ' SOCS1%0')  (' PPM1A%0'  ' DUSP6%0')  (' PPM1A%0'  ' STAT3%0')  (' PPM1A%0'  ' LIMK2%0')  (' PPM1A%0'  ' EP300%0')  (' PPM1A%0'  ' STAT1%0')  (' PPM1A%0'  ' IKBKB%0')  (' PPM1A%0'  ' SRF%0')  (' PPM1A%0'  ' PIAS1%0')  (' PPM1A%0'  ' TRAF6%0')  (' PPM1A%0'  ' SOCS1_g%0')  (' PPM1A%0'  ' ISGF3_c%0')  (' PPM1A%0'  ' STAT2%0')  (' PPM1A%0'  ' CFLAR%0')  (' PPM1A%0'  ' SMAD2%0')  (' PPM1A%0'  ' MDM2_g%0')  (' PPM1A%0'  ' BAX%0')  (' PPM1A%0'  ' PRKACA%0')  (' PPM1A%0'  ' TGFB1%0')  (' PPM1A%0'  ' MAP3K8%0')  (' PPM1A%0'  ' TSC_f%0')  (' PPM1A%0'  ' SMAD4%0')  (' PPM1A%0'  ' BAD%0')  (' PPM1A%0'  ' MAP3K5%0')  (' PPM1A%0'  ' AKT1S1%0')  (' PPM1A%0'  ' SKI%0')  (' PPM1A%0'  ' SMAD3%0')  (' PPM1A%0'  ' MAPKAPK2%0')  (' PPM1A%0'  ' DUSP1_g%0')  (' PPM1A%0'  ' MSK_f%0')  (' PPM1A%0'  ' GRAP2%0')  (' PPM1A%0'  ' TAB_f%0')  (' PPM1A%0'  ' ATF2%0')  (' PPM1A%0'  ' SMAD5%0')  (' PPM1A%0'  ' SMAD1%0')  (' PPM1A%0'  ' FOS%0')  (' PPM1A%0'  ' JUN%0')  (' PPM1A%0'  ' MAP3K7%0')  (' PPM1A%0'  ' NLK%0')  (' PPM1A%0'  ' SMAD7_g%0')  (' PPM1A%0'  ' SMAD6_g%0')  (' PPM1A%0'  ' AP1_c%0')  (' PPM1A%0'  ' ACVR1%0')  (' PPM1A%0'  ' PTPN6%0')  (' PPM1A%0'  ' CDC42%0')  (' PPM1A%0'  ' GRB2%0')  (' PPM1A%0'  ' TGFBR1%0')  (' PPM1A%0'  ' SMURF1%0')  (' PPM1A%0'  ' SMURF2%0')  (' PPM1A%0'  ' RHOA%0')  (' PPM1A%0'  ' BMPR2%0')  (' PPM1A%0'  ' PARD6A%0')  (' PPM1A%0'  ' DAAM1%0')  (' PPM1A%0'  ' SFRP1_g%0')  (' PPM1A%0'  ' CFL_f%0')  (' PPM1A%0'  ' PAK1%0')  (' PPM1A%0'  ' MAP3K11%0')  (' PPM1A%0'  ' MAP3K4%0')  (' PPM1A%0'  ' LIMK1%0')  (' PPM1A%0'  ' ROCK1%0')  (' PPM1A%0'  ' ITCH%0')  (' PPM1A%0'  ' ARHGAP24%0')  (' PPM1A%0'  ' TIAM1%0')  (' PPM1A%0'  ' RND3%0')  (' PPM1A%0'  ' MAPK8IP3%0')  (' PPM1A%0'  ' MXD1%0')  (' PPM1A%0'  ' PIP3%0')  (' CFL_f%0'  ' SRC%0')  (' CFL_f%0'  ' CSK%0')  (' CFL_f%0'  ' CHUK%0')  (' CFL_f%0'  ' RAC_f%0')  (' CFL_f%0'  ' DUSP1%0')  (' CFL_f%0'  ' TGFBR2%0')  (' CFL_f%0'  ' ILR_f%0')  (' CFL_f%0'  ' SYK%0')  (' CFL_f%0'  ' IRAK1%0')  (' CFL_f%0'  ' SHC1%0')  (' CFL_f%0'  ' JAK_f%0')  (' CFL_f%0'  ' CBPp300_c%0')  (' CFL_f%0'  ' SKP2%0')  (' CFL_f%0'  ' TP53%0')  (' CFL_f%0'  ' SMAD7%0')  (' CFL_f%0'  ' SMAD6%0')  (' CFL_f%0'  ' DKK_f%0')  (' CFL_f%0'  ' FOXO_f%0')  (' CFL_f%0'  ' TCF7_f%0')  (' CFL_f%0'  ' DKK_g%0')  (' CFL_f%0'  ' MYC%0')  (' CFL_f%0'  ' CCND1%0')  (' CFL_f%0'  ' EGR1%0')  (' CFL_f%0'  ' MMP_f%0')  (' CFL_f%0'  ' PTEN_g%0')  (' CFL_f%0'  ' RTPK_f%0')  (' CFL_f%0'  ' CTNNB1%0')  (' CFL_f%0'  'LEF1%0')  (' CFL_f%0'  'SFRP1%0')  (' CFL_f%0'  'FZD_f%0')  (' CFL_f%0'  ' CASP8%0')  (' CFL_f%0'  ' REL_f%0')  (' CFL_f%0'  ' NFKB_f%0')  (' CFL_f%0'  ' DVL_f%0')  (' CFL_f%0'  ' LRP_f%0')  (' CFL_f%0'  ' BTRC%0')  (' CFL_f%0'  ' CK1_f%0')  (' CFL_f%0'  ' AXIN1%0')  (' CFL_f%0'  ' mTORC2_c%0')  (' CFL_f%0'  ' PDPK1%0')  (' CFL_f%0'  ' MEK_f%0')  (' CFL_f%0'  ' CYCS%0')  (' CFL_f%0'  ' CASP9%0')  (' CFL_f%0'  ' GSK3_f%0')  (' CFL_f%0'  ' IRS1%0')  (' CFL_f%0'  ' MDM2%0')  (' CFL_f%0'  ' AKT_f%0')  (' CFL_f%0'  ' BCL2%0')  (' CFL_f%0'  ' RAF_f%0')  (' CFL_f%0'  ' mTORC1_c%0')  (' CFL_f%0'  ' RHEB%0')  (' CFL_f%0'  ' RTPK_g%0')  (' CFL_f%0'  ' PTEN%0')  (' CFL_f%0'  ' CASP3%0')  (' CFL_f%0'  ' PIK3CA%0')  (' CFL_f%0'  ' CREBBP%0')  (' CFL_f%0'  ' PTPN11%0')  (' CFL_f%0'  ' KRAS%0')  (' CFL_f%0'  ' MAP2K4%0')  (' CFL_f%0'  ' MAP2K7%0')  (' CFL_f%0'  ' MAPK14%0')  (' CFL_f%0'  ' JNK_f%0')  (' CFL_f%0'  ' MAP2K3%0')  (' CFL_f%0'  ' ERK_f%0')  (' CFL_f%0'  ' LIF%0')  (' CFL_f%0'  ' PPP1CA%0')  (' CFL_f%0'  ' GAB_f%0')  (' CFL_f%0'  ' SOS1%0')  (' CFL_f%0'  ' PRKCA%0')  (' CFL_f%0'  ' VAV1%0')  (' CFL_f%0'  ' PLCG1%0')  (' CFL_f%0'  ' PRKCD%0')  (' CFL_f%0'  ' RSK_f%0')  (' CFL_f%0'  ' S6K_f%0')  (' CFL_f%0'  ' PLK1%0')  (' CFL_f%0'  ' ILK%0')  (' CFL_f%0'  ' SOCS1%0')  (' CFL_f%0'  ' DUSP6%0')  (' CFL_f%0'  ' STAT3%0')  (' CFL_f%0'  ' LIMK2%0')  (' CFL_f%0'  ' EP300%0')  (' CFL_f%0'  ' STAT1%0')  (' CFL_f%0'  ' IKBKB%0')  (' CFL_f%0'  ' SRF%0')  (' CFL_f%0'  ' PIAS1%0')  (' CFL_f%0'  ' TRAF6%0')  (' CFL_f%0'  ' SOCS1_g%0')  (' CFL_f%0'  ' ISGF3_c%0')  (' CFL_f%0'  ' STAT2%0')  (' CFL_f%0'  ' CFLAR%0')  (' CFL_f%0'  ' SMAD2%0')  (' CFL_f%0'  ' MDM2_g%0')  (' CFL_f%0'  ' BAX%0')  (' CFL_f%0'  ' PRKACA%0')  (' CFL_f%0'  ' TGFB1%0')  (' CFL_f%0'  ' MAP3K8%0')  (' CFL_f%0'  ' TSC_f%0')  (' CFL_f%0'  ' SMAD4%0')  (' CFL_f%0'  ' BAD%0')  (' CFL_f%0'  ' MAP3K5%0')  (' CFL_f%0'  ' AKT1S1%0')  (' CFL_f%0'  ' SKI%0')  (' CFL_f%0'  ' SMAD3%0')  (' CFL_f%0'  ' MAPKAPK2%0')  (' CFL_f%0'  ' DUSP1_g%0')  (' CFL_f%0'  ' MSK_f%0')  (' CFL_f%0'  ' GRAP2%0')  (' CFL_f%0'  ' TAB_f%0')  (' CFL_f%0'  ' ATF2%0')  (' CFL_f%0'  ' SMAD5%0')  (' CFL_f%0'  ' SMAD1%0')  (' CFL_f%0'  ' FOS%0')  (' CFL_f%0'  ' JUN%0')  (' CFL_f%0'  ' MAP3K7%0')  (' CFL_f%0'  ' NLK%0')  (' CFL_f%0'  ' SMAD7_g%0')  (' CFL_f%0'  ' SMAD6_g%0')  (' CFL_f%0'  ' AP1_c%0')  (' CFL_f%0'  ' ACVR1%0')  (' CFL_f%0'  ' PTPN6%0')  (' CFL_f%0'  ' CDC42%0')  (' CFL_f%0'  ' GRB2%0')  (' CFL_f%0'  ' TGFBR1%0')  (' CFL_f%0'  ' SMURF1%0')  (' CFL_f%0'  ' SMURF2%0')  (' CFL_f%0'  ' RHOA%0')  (' CFL_f%0'  ' BMPR2%0')  (' CFL_f%0'  ' PARD6A%0')  (' CFL_f%0'  ' DAAM1%0')  (' CFL_f%0'  ' SFRP1_g%0')  (' CFL_f%0'  ' PPM1A%0')  (' CFL_f%0'  ' PAK1%0')  (' CFL_f%0'  ' MAP3K11%0')  (' CFL_f%0'  ' MAP3K4%0')  (' CFL_f%0'  ' LIMK1%0')  (' CFL_f%0'  ' ROCK1%0')  (' CFL_f%0'  ' ITCH%0')  (' CFL_f%0'  ' ARHGAP24%0')  (' CFL_f%0'  ' TIAM1%0')  (' CFL_f%0'  ' RND3%0')  (' CFL_f%0'  ' MAPK8IP3%0')  (' CFL_f%0'  ' MXD1%0')  (' CFL_f%0'  ' PIP3%0')  (' PAK1%0'  ' SRC%0')  (' PAK1%0'  ' CSK%0')  (' PAK1%0'  ' CHUK%0')  (' PAK1%0'  ' RAC_f%0')  (' PAK1%0'  ' DUSP1%0')  (' PAK1%0'  ' TGFBR2%0')  (' PAK1%0'  ' ILR_f%0')  (' PAK1%0'  ' SYK%0')  (' PAK1%0'  ' IRAK1%0')  (' PAK1%0'  ' SHC1%0')  (' PAK1%0'  ' JAK_f%0')  (' PAK1%0'  ' CBPp300_c%0')  (' PAK1%0'  ' SKP2%0')  (' PAK1%0'  ' TP53%0')  (' PAK1%0'  ' SMAD7%0')  (' PAK1%0'  ' SMAD6%0')  (' PAK1%0'  ' DKK_f%0')  (' PAK1%0'  ' FOXO_f%0')  (' PAK1%0'  ' TCF7_f%0')  (' PAK1%0'  ' DKK_g%0')  (' PAK1%0'  ' MYC%0')  (' PAK1%0'  ' CCND1%0')  (' PAK1%0'  ' EGR1%0')  (' PAK1%0'  ' MMP_f%0')  (' PAK1%0'  ' PTEN_g%0')  (' PAK1%0'  ' RTPK_f%0')  (' PAK1%0'  ' CTNNB1%0')  (' PAK1%0'  'LEF1%0')  (' PAK1%0'  'SFRP1%0')  (' PAK1%0'  'FZD_f%0')  (' PAK1%0'  ' CASP8%0')  (' PAK1%0'  ' REL_f%0')  (' PAK1%0'  ' NFKB_f%0')  (' PAK1%0'  ' DVL_f%0')  (' PAK1%0'  ' LRP_f%0')  (' PAK1%0'  ' BTRC%0')  (' PAK1%0'  ' CK1_f%0')  (' PAK1%0'  ' AXIN1%0')  (' PAK1%0'  ' mTORC2_c%0')  (' PAK1%0'  ' PDPK1%0')  (' PAK1%0'  ' MEK_f%0')  (' PAK1%0'  ' CYCS%0')  (' PAK1%0'  ' CASP9%0')  (' PAK1%0'  ' GSK3_f%0')  (' PAK1%0'  ' IRS1%0')  (' PAK1%0'  ' MDM2%0')  (' PAK1%0'  ' AKT_f%0')  (' PAK1%0'  ' BCL2%0')  (' PAK1%0'  ' RAF_f%0')  (' PAK1%0'  ' mTORC1_c%0')  (' PAK1%0'  ' RHEB%0')  (' PAK1%0'  ' RTPK_g%0')  (' PAK1%0'  ' PTEN%0')  (' PAK1%0'  ' CASP3%0')  (' PAK1%0'  ' PIK3CA%0')  (' PAK1%0'  ' CREBBP%0')  (' PAK1%0'  ' PTPN11%0')  (' PAK1%0'  ' KRAS%0')  (' PAK1%0'  ' MAP2K4%0')  (' PAK1%0'  ' MAP2K7%0')  (' PAK1%0'  ' MAPK14%0')  (' PAK1%0'  ' JNK_f%0')  (' PAK1%0'  ' MAP2K3%0')  (' PAK1%0'  ' ERK_f%0')  (' PAK1%0'  ' LIF%0')  (' PAK1%0'  ' PPP1CA%0')  (' PAK1%0'  ' GAB_f%0')  (' PAK1%0'  ' SOS1%0')  (' PAK1%0'  ' PRKCA%0')  (' PAK1%0'  ' VAV1%0')  (' PAK1%0'  ' PLCG1%0')  (' PAK1%0'  ' PRKCD%0')  (' PAK1%0'  ' RSK_f%0')  (' PAK1%0'  ' S6K_f%0')  (' PAK1%0'  ' PLK1%0')  (' PAK1%0'  ' ILK%0')  (' PAK1%0'  ' SOCS1%0')  (' PAK1%0'  ' DUSP6%0')  (' PAK1%0'  ' STAT3%0')  (' PAK1%0'  ' LIMK2%0')  (' PAK1%0'  ' EP300%0')  (' PAK1%0'  ' STAT1%0')  (' PAK1%0'  ' IKBKB%0')  (' PAK1%0'  ' SRF%0')  (' PAK1%0'  ' PIAS1%0')  (' PAK1%0'  ' TRAF6%0')  (' PAK1%0'  ' SOCS1_g%0')  (' PAK1%0'  ' ISGF3_c%0')  (' PAK1%0'  ' STAT2%0')  (' PAK1%0'  ' CFLAR%0')  (' PAK1%0'  ' SMAD2%0')  (' PAK1%0'  ' MDM2_g%0')  (' PAK1%0'  ' BAX%0')  (' PAK1%0'  ' PRKACA%0')  (' PAK1%0'  ' TGFB1%0')  (' PAK1%0'  ' MAP3K8%0')  (' PAK1%0'  ' TSC_f%0')  (' PAK1%0'  ' SMAD4%0')  (' PAK1%0'  ' BAD%0')  (' PAK1%0'  ' MAP3K5%0')  (' PAK1%0'  ' AKT1S1%0')  (' PAK1%0'  ' SKI%0')  (' PAK1%0'  ' SMAD3%0')  (' PAK1%0'  ' MAPKAPK2%0')  (' PAK1%0'  ' DUSP1_g%0')  (' PAK1%0'  ' MSK_f%0')  (' PAK1%0'  ' GRAP2%0')  (' PAK1%0'  ' TAB_f%0')  (' PAK1%0'  ' ATF2%0')  (' PAK1%0'  ' SMAD5%0')  (' PAK1%0'  ' SMAD1%0')  (' PAK1%0'  ' FOS%0')  (' PAK1%0'  ' JUN%0')  (' PAK1%0'  ' MAP3K7%0')  (' PAK1%0'  ' NLK%0')  (' PAK1%0'  ' SMAD7_g%0')  (' PAK1%0'  ' SMAD6_g%0')  (' PAK1%0'  ' AP1_c%0')  (' PAK1%0'  ' ACVR1%0')  (' PAK1%0'  ' PTPN6%0')  (' PAK1%0'  ' CDC42%0')  (' PAK1%0'  ' GRB2%0')  (' PAK1%0'  ' TGFBR1%0')  (' PAK1%0'  ' SMURF1%0')  (' PAK1%0'  ' SMURF2%0')  (' PAK1%0'  ' RHOA%0')  (' PAK1%0'  ' BMPR2%0')  (' PAK1%0'  ' PARD6A%0')  (' PAK1%0'  ' DAAM1%0')  (' PAK1%0'  ' SFRP1_g%0')  (' PAK1%0'  ' PPM1A%0')  (' PAK1%0'  ' CFL_f%0')  (' PAK1%0'  ' MAP3K11%0')  (' PAK1%0'  ' MAP3K4%0')  (' PAK1%0'  ' LIMK1%0')  (' PAK1%0'  ' ROCK1%0')  (' PAK1%0'  ' ITCH%0')  (' PAK1%0'  ' ARHGAP24%0')  (' PAK1%0'  ' TIAM1%0')  (' PAK1%0'  ' RND3%0')  (' PAK1%0'  ' MAPK8IP3%0')  (' PAK1%0'  ' MXD1%0')  (' PAK1%0'  ' PIP3%0')  (' MAP3K11%0'  ' SRC%0')  (' MAP3K11%0'  ' CSK%0')  (' MAP3K11%0'  ' CHUK%0')  (' MAP3K11%0'  ' RAC_f%0')  (' MAP3K11%0'  ' DUSP1%0')  (' MAP3K11%0'  ' TGFBR2%0')  (' MAP3K11%0'  ' ILR_f%0')  (' MAP3K11%0'  ' SYK%0')  (' MAP3K11%0'  ' IRAK1%0')  (' MAP3K11%0'  ' SHC1%0')  (' MAP3K11%0'  ' JAK_f%0')  (' MAP3K11%0'  ' CBPp300_c%0')  (' MAP3K11%0'  ' SKP2%0')  (' MAP3K11%0'  ' TP53%0')  (' MAP3K11%0'  ' SMAD7%0')  (' MAP3K11%0'  ' SMAD6%0')  (' MAP3K11%0'  ' DKK_f%0')  (' MAP3K11%0'  ' FOXO_f%0')  (' MAP3K11%0'  ' TCF7_f%0')  (' MAP3K11%0'  ' DKK_g%0')  (' MAP3K11%0'  ' MYC%0')  (' MAP3K11%0'  ' CCND1%0')  (' MAP3K11%0'  ' EGR1%0')  (' MAP3K11%0'  ' MMP_f%0')  (' MAP3K11%0'  ' PTEN_g%0')  (' MAP3K11%0'  ' RTPK_f%0')  (' MAP3K11%0'  ' CTNNB1%0')  (' MAP3K11%0'  'LEF1%0')  (' MAP3K11%0'  'SFRP1%0')  (' MAP3K11%0'  'FZD_f%0')  (' MAP3K11%0'  ' CASP8%0')  (' MAP3K11%0'  ' REL_f%0')  (' MAP3K11%0'  ' NFKB_f%0')  (' MAP3K11%0'  ' DVL_f%0')  (' MAP3K11%0'  ' LRP_f%0')  (' MAP3K11%0'  ' BTRC%0')  (' MAP3K11%0'  ' CK1_f%0')  (' MAP3K11%0'  ' AXIN1%0')  (' MAP3K11%0'  ' mTORC2_c%0')  (' MAP3K11%0'  ' PDPK1%0')  (' MAP3K11%0'  ' MEK_f%0')  (' MAP3K11%0'  ' CYCS%0')  (' MAP3K11%0'  ' CASP9%0')  (' MAP3K11%0'  ' GSK3_f%0')  (' MAP3K11%0'  ' IRS1%0')  (' MAP3K11%0'  ' MDM2%0')  (' MAP3K11%0'  ' AKT_f%0')  (' MAP3K11%0'  ' BCL2%0')  (' MAP3K11%0'  ' RAF_f%0')  (' MAP3K11%0'  ' mTORC1_c%0')  (' MAP3K11%0'  ' RHEB%0')  (' MAP3K11%0'  ' RTPK_g%0')  (' MAP3K11%0'  ' PTEN%0')  (' MAP3K11%0'  ' CASP3%0')  (' MAP3K11%0'  ' PIK3CA%0')  (' MAP3K11%0'  ' CREBBP%0')  (' MAP3K11%0'  ' PTPN11%0')  (' MAP3K11%0'  ' KRAS%0')  (' MAP3K11%0'  ' MAP2K4%0')  (' MAP3K11%0'  ' MAP2K7%0')  (' MAP3K11%0'  ' MAPK14%0')  (' MAP3K11%0'  ' JNK_f%0')  (' MAP3K11%0'  ' MAP2K3%0')  (' MAP3K11%0'  ' ERK_f%0')  (' MAP3K11%0'  ' LIF%0')  (' MAP3K11%0'  ' PPP1CA%0')  (' MAP3K11%0'  ' GAB_f%0')  (' MAP3K11%0'  ' SOS1%0')  (' MAP3K11%0'  ' PRKCA%0')  (' MAP3K11%0'  ' VAV1%0')  (' MAP3K11%0'  ' PLCG1%0')  (' MAP3K11%0'  ' PRKCD%0')  (' MAP3K11%0'  ' RSK_f%0')  (' MAP3K11%0'  ' S6K_f%0')  (' MAP3K11%0'  ' PLK1%0')  (' MAP3K11%0'  ' ILK%0')  (' MAP3K11%0'  ' SOCS1%0')  (' MAP3K11%0'  ' DUSP6%0')  (' MAP3K11%0'  ' STAT3%0')  (' MAP3K11%0'  ' LIMK2%0')  (' MAP3K11%0'  ' EP300%0')  (' MAP3K11%0'  ' STAT1%0')  (' MAP3K11%0'  ' IKBKB%0')  (' MAP3K11%0'  ' SRF%0')  (' MAP3K11%0'  ' PIAS1%0')  (' MAP3K11%0'  ' TRAF6%0')  (' MAP3K11%0'  ' SOCS1_g%0')  (' MAP3K11%0'  ' ISGF3_c%0')  (' MAP3K11%0'  ' STAT2%0')  (' MAP3K11%0'  ' CFLAR%0')  (' MAP3K11%0'  ' SMAD2%0')  (' MAP3K11%0'  ' MDM2_g%0')  (' MAP3K11%0'  ' BAX%0')  (' MAP3K11%0'  ' PRKACA%0')  (' MAP3K11%0'  ' TGFB1%0')  (' MAP3K11%0'  ' MAP3K8%0')  (' MAP3K11%0'  ' TSC_f%0')  (' MAP3K11%0'  ' SMAD4%0')  (' MAP3K11%0'  ' BAD%0')  (' MAP3K11%0'  ' MAP3K5%0')  (' MAP3K11%0'  ' AKT1S1%0')  (' MAP3K11%0'  ' SKI%0')  (' MAP3K11%0'  ' SMAD3%0')  (' MAP3K11%0'  ' MAPKAPK2%0')  (' MAP3K11%0'  ' DUSP1_g%0')  (' MAP3K11%0'  ' MSK_f%0')  (' MAP3K11%0'  ' GRAP2%0')  (' MAP3K11%0'  ' TAB_f%0')  (' MAP3K11%0'  ' ATF2%0')  (' MAP3K11%0'  ' SMAD5%0')  (' MAP3K11%0'  ' SMAD1%0')  (' MAP3K11%0'  ' FOS%0')  (' MAP3K11%0'  ' JUN%0')  (' MAP3K11%0'  ' MAP3K7%0')  (' MAP3K11%0'  ' NLK%0')  (' MAP3K11%0'  ' SMAD7_g%0')  (' MAP3K11%0'  ' SMAD6_g%0')  (' MAP3K11%0'  ' AP1_c%0')  (' MAP3K11%0'  ' ACVR1%0')  (' MAP3K11%0'  ' PTPN6%0')  (' MAP3K11%0'  ' CDC42%0')  (' MAP3K11%0'  ' GRB2%0')  (' MAP3K11%0'  ' TGFBR1%0')  (' MAP3K11%0'  ' SMURF1%0')  (' MAP3K11%0'  ' SMURF2%0')  (' MAP3K11%0'  ' RHOA%0')  (' MAP3K11%0'  ' BMPR2%0')  (' MAP3K11%0'  ' PARD6A%0')  (' MAP3K11%0'  ' DAAM1%0')  (' MAP3K11%0'  ' SFRP1_g%0')  (' MAP3K11%0'  ' PPM1A%0')  (' MAP3K11%0'  ' CFL_f%0')  (' MAP3K11%0'  ' PAK1%0')  (' MAP3K11%0'  ' MAP3K4%0')  (' MAP3K11%0'  ' LIMK1%0')  (' MAP3K11%0'  ' ROCK1%0')  (' MAP3K11%0'  ' ITCH%0')  (' MAP3K11%0'  ' ARHGAP24%0')  (' MAP3K11%0'  ' TIAM1%0')  (' MAP3K11%0'  ' RND3%0')  (' MAP3K11%0'  ' MAPK8IP3%0')  (' MAP3K11%0'  ' MXD1%0')  (' MAP3K11%0'  ' PIP3%0')  (' MAP3K4%0'  ' SRC%0')  (' MAP3K4%0'  ' CSK%0')  (' MAP3K4%0'  ' CHUK%0')  (' MAP3K4%0'  ' RAC_f%0')  (' MAP3K4%0'  ' DUSP1%0')  (' MAP3K4%0'  ' TGFBR2%0')  (' MAP3K4%0'  ' ILR_f%0')  (' MAP3K4%0'  ' SYK%0')  (' MAP3K4%0'  ' IRAK1%0')  (' MAP3K4%0'  ' SHC1%0')  (' MAP3K4%0'  ' JAK_f%0')  (' MAP3K4%0'  ' CBPp300_c%0')  (' MAP3K4%0'  ' SKP2%0')  (' MAP3K4%0'  ' TP53%0')  (' MAP3K4%0'  ' SMAD7%0')  (' MAP3K4%0'  ' SMAD6%0')  (' MAP3K4%0'  ' DKK_f%0')  (' MAP3K4%0'  ' FOXO_f%0')  (' MAP3K4%0'  ' TCF7_f%0')  (' MAP3K4%0'  ' DKK_g%0')  (' MAP3K4%0'  ' MYC%0')  (' MAP3K4%0'  ' CCND1%0')  (' MAP3K4%0'  ' EGR1%0')  (' MAP3K4%0'  ' MMP_f%0')  (' MAP3K4%0'  ' PTEN_g%0')  (' MAP3K4%0'  ' RTPK_f%0')  (' MAP3K4%0'  ' CTNNB1%0')  (' MAP3K4%0'  'LEF1%0')  (' MAP3K4%0'  'SFRP1%0')  (' MAP3K4%0'  'FZD_f%0')  (' MAP3K4%0'  ' CASP8%0')  (' MAP3K4%0'  ' REL_f%0')  (' MAP3K4%0'  ' NFKB_f%0')  (' MAP3K4%0'  ' DVL_f%0')  (' MAP3K4%0'  ' LRP_f%0')  (' MAP3K4%0'  ' BTRC%0')  (' MAP3K4%0'  ' CK1_f%0')  (' MAP3K4%0'  ' AXIN1%0')  (' MAP3K4%0'  ' mTORC2_c%0')  (' MAP3K4%0'  ' PDPK1%0')  (' MAP3K4%0'  ' MEK_f%0')  (' MAP3K4%0'  ' CYCS%0')  (' MAP3K4%0'  ' CASP9%0')  (' MAP3K4%0'  ' GSK3_f%0')  (' MAP3K4%0'  ' IRS1%0')  (' MAP3K4%0'  ' MDM2%0')  (' MAP3K4%0'  ' AKT_f%0')  (' MAP3K4%0'  ' BCL2%0')  (' MAP3K4%0'  ' RAF_f%0')  (' MAP3K4%0'  ' mTORC1_c%0')  (' MAP3K4%0'  ' RHEB%0')  (' MAP3K4%0'  ' RTPK_g%0')  (' MAP3K4%0'  ' PTEN%0')  (' MAP3K4%0'  ' CASP3%0')  (' MAP3K4%0'  ' PIK3CA%0')  (' MAP3K4%0'  ' CREBBP%0')  (' MAP3K4%0'  ' PTPN11%0')  (' MAP3K4%0'  ' KRAS%0')  (' MAP3K4%0'  ' MAP2K4%0')  (' MAP3K4%0'  ' MAP2K7%0')  (' MAP3K4%0'  ' MAPK14%0')  (' MAP3K4%0'  ' JNK_f%0')  (' MAP3K4%0'  ' MAP2K3%0')  (' MAP3K4%0'  ' ERK_f%0')  (' MAP3K4%0'  ' LIF%0')  (' MAP3K4%0'  ' PPP1CA%0')  (' MAP3K4%0'  ' GAB_f%0')  (' MAP3K4%0'  ' SOS1%0')  (' MAP3K4%0'  ' PRKCA%0')  (' MAP3K4%0'  ' VAV1%0')  (' MAP3K4%0'  ' PLCG1%0')  (' MAP3K4%0'  ' PRKCD%0')  (' MAP3K4%0'  ' RSK_f%0')  (' MAP3K4%0'  ' S6K_f%0')  (' MAP3K4%0'  ' PLK1%0')  (' MAP3K4%0'  ' ILK%0')  (' MAP3K4%0'  ' SOCS1%0')  (' MAP3K4%0'  ' DUSP6%0')  (' MAP3K4%0'  ' STAT3%0')  (' MAP3K4%0'  ' LIMK2%0')  (' MAP3K4%0'  ' EP300%0')  (' MAP3K4%0'  ' STAT1%0')  (' MAP3K4%0'  ' IKBKB%0')  (' MAP3K4%0'  ' SRF%0')  (' MAP3K4%0'  ' PIAS1%0')  (' MAP3K4%0'  ' TRAF6%0')  (' MAP3K4%0'  ' SOCS1_g%0')  (' MAP3K4%0'  ' ISGF3_c%0')  (' MAP3K4%0'  ' STAT2%0')  (' MAP3K4%0'  ' CFLAR%0')  (' MAP3K4%0'  ' SMAD2%0')  (' MAP3K4%0'  ' MDM2_g%0')  (' MAP3K4%0'  ' BAX%0')  (' MAP3K4%0'  ' PRKACA%0')  (' MAP3K4%0'  ' TGFB1%0')  (' MAP3K4%0'  ' MAP3K8%0')  (' MAP3K4%0'  ' TSC_f%0')  (' MAP3K4%0'  ' SMAD4%0')  (' MAP3K4%0'  ' BAD%0')  (' MAP3K4%0'  ' MAP3K5%0')  (' MAP3K4%0'  ' AKT1S1%0')  (' MAP3K4%0'  ' SKI%0')  (' MAP3K4%0'  ' SMAD3%0')  (' MAP3K4%0'  ' MAPKAPK2%0')  (' MAP3K4%0'  ' DUSP1_g%0')  (' MAP3K4%0'  ' MSK_f%0')  (' MAP3K4%0'  ' GRAP2%0')  (' MAP3K4%0'  ' TAB_f%0')  (' MAP3K4%0'  ' ATF2%0')  (' MAP3K4%0'  ' SMAD5%0')  (' MAP3K4%0'  ' SMAD1%0')  (' MAP3K4%0'  ' FOS%0')  (' MAP3K4%0'  ' JUN%0')  (' MAP3K4%0'  ' MAP3K7%0')  (' MAP3K4%0'  ' NLK%0')  (' MAP3K4%0'  ' SMAD7_g%0')  (' MAP3K4%0'  ' SMAD6_g%0')  (' MAP3K4%0'  ' AP1_c%0')  (' MAP3K4%0'  ' ACVR1%0')  (' MAP3K4%0'  ' PTPN6%0')  (' MAP3K4%0'  ' CDC42%0')  (' MAP3K4%0'  ' GRB2%0')  (' MAP3K4%0'  ' TGFBR1%0')  (' MAP3K4%0'  ' SMURF1%0')  (' MAP3K4%0'  ' SMURF2%0')  (' MAP3K4%0'  ' RHOA%0')  (' MAP3K4%0'  ' BMPR2%0')  (' MAP3K4%0'  ' PARD6A%0')  (' MAP3K4%0'  ' DAAM1%0')  (' MAP3K4%0'  ' SFRP1_g%0')  (' MAP3K4%0'  ' PPM1A%0')  (' MAP3K4%0'  ' CFL_f%0')  (' MAP3K4%0'  ' PAK1%0')  (' MAP3K4%0'  ' MAP3K11%0')  (' MAP3K4%0'  ' LIMK1%0')  (' MAP3K4%0'  ' ROCK1%0')  (' MAP3K4%0'  ' ITCH%0')  (' MAP3K4%0'  ' ARHGAP24%0')  (' MAP3K4%0'  ' TIAM1%0')  (' MAP3K4%0'  ' RND3%0')  (' MAP3K4%0'  ' MAPK8IP3%0')  (' MAP3K4%0'  ' MXD1%0')  (' MAP3K4%0'  ' PIP3%0')  (' LIMK1%0'  ' SRC%0')  (' LIMK1%0'  ' CSK%0')  (' LIMK1%0'  ' CHUK%0')  (' LIMK1%0'  ' RAC_f%0')  (' LIMK1%0'  ' DUSP1%0')  (' LIMK1%0'  ' TGFBR2%0')  (' LIMK1%0'  ' ILR_f%0')  (' LIMK1%0'  ' SYK%0')  (' LIMK1%0'  ' IRAK1%0')  (' LIMK1%0'  ' SHC1%0')  (' LIMK1%0'  ' JAK_f%0')  (' LIMK1%0'  ' CBPp300_c%0')  (' LIMK1%0'  ' SKP2%0')  (' LIMK1%0'  ' TP53%0')  (' LIMK1%0'  ' SMAD7%0')  (' LIMK1%0'  ' SMAD6%0')  (' LIMK1%0'  ' DKK_f%0')  (' LIMK1%0'  ' FOXO_f%0')  (' LIMK1%0'  ' TCF7_f%0')  (' LIMK1%0'  ' DKK_g%0')  (' LIMK1%0'  ' MYC%0')  (' LIMK1%0'  ' CCND1%0')  (' LIMK1%0'  ' EGR1%0')  (' LIMK1%0'  ' MMP_f%0')  (' LIMK1%0'  ' PTEN_g%0')  (' LIMK1%0'  ' RTPK_f%0')  (' LIMK1%0'  ' CTNNB1%0')  (' LIMK1%0'  'LEF1%0')  (' LIMK1%0'  'SFRP1%0')  (' LIMK1%0'  'FZD_f%0')  (' LIMK1%0'  ' CASP8%0')  (' LIMK1%0'  ' REL_f%0')  (' LIMK1%0'  ' NFKB_f%0')  (' LIMK1%0'  ' DVL_f%0')  (' LIMK1%0'  ' LRP_f%0')  (' LIMK1%0'  ' BTRC%0')  (' LIMK1%0'  ' CK1_f%0')  (' LIMK1%0'  ' AXIN1%0')  (' LIMK1%0'  ' mTORC2_c%0')  (' LIMK1%0'  ' PDPK1%0')  (' LIMK1%0'  ' MEK_f%0')  (' LIMK1%0'  ' CYCS%0')  (' LIMK1%0'  ' CASP9%0')  (' LIMK1%0'  ' GSK3_f%0')  (' LIMK1%0'  ' IRS1%0')  (' LIMK1%0'  ' MDM2%0')  (' LIMK1%0'  ' AKT_f%0')  (' LIMK1%0'  ' BCL2%0')  (' LIMK1%0'  ' RAF_f%0')  (' LIMK1%0'  ' mTORC1_c%0')  (' LIMK1%0'  ' RHEB%0')  (' LIMK1%0'  ' RTPK_g%0')  (' LIMK1%0'  ' PTEN%0')  (' LIMK1%0'  ' CASP3%0')  (' LIMK1%0'  ' PIK3CA%0')  (' LIMK1%0'  ' CREBBP%0')  (' LIMK1%0'  ' PTPN11%0')  (' LIMK1%0'  ' KRAS%0')  (' LIMK1%0'  ' MAP2K4%0')  (' LIMK1%0'  ' MAP2K7%0')  (' LIMK1%0'  ' MAPK14%0')  (' LIMK1%0'  ' JNK_f%0')  (' LIMK1%0'  ' MAP2K3%0')  (' LIMK1%0'  ' ERK_f%0')  (' LIMK1%0'  ' LIF%0')  (' LIMK1%0'  ' PPP1CA%0')  (' LIMK1%0'  ' GAB_f%0')  (' LIMK1%0'  ' SOS1%0')  (' LIMK1%0'  ' PRKCA%0')  (' LIMK1%0'  ' VAV1%0')  (' LIMK1%0'  ' PLCG1%0')  (' LIMK1%0'  ' PRKCD%0')  (' LIMK1%0'  ' RSK_f%0')  (' LIMK1%0'  ' S6K_f%0')  (' LIMK1%0'  ' PLK1%0')  (' LIMK1%0'  ' ILK%0')  (' LIMK1%0'  ' SOCS1%0')  (' LIMK1%0'  ' DUSP6%0')  (' LIMK1%0'  ' STAT3%0')  (' LIMK1%0'  ' LIMK2%0')  (' LIMK1%0'  ' EP300%0')  (' LIMK1%0'  ' STAT1%0')  (' LIMK1%0'  ' IKBKB%0')  (' LIMK1%0'  ' SRF%0')  (' LIMK1%0'  ' PIAS1%0')  (' LIMK1%0'  ' TRAF6%0')  (' LIMK1%0'  ' SOCS1_g%0')  (' LIMK1%0'  ' ISGF3_c%0')  (' LIMK1%0'  ' STAT2%0')  (' LIMK1%0'  ' CFLAR%0')  (' LIMK1%0'  ' SMAD2%0')  (' LIMK1%0'  ' MDM2_g%0')  (' LIMK1%0'  ' BAX%0')  (' LIMK1%0'  ' PRKACA%0')  (' LIMK1%0'  ' TGFB1%0')  (' LIMK1%0'  ' MAP3K8%0')  (' LIMK1%0'  ' TSC_f%0')  (' LIMK1%0'  ' SMAD4%0')  (' LIMK1%0'  ' BAD%0')  (' LIMK1%0'  ' MAP3K5%0')  (' LIMK1%0'  ' AKT1S1%0')  (' LIMK1%0'  ' SKI%0')  (' LIMK1%0'  ' SMAD3%0')  (' LIMK1%0'  ' MAPKAPK2%0')  (' LIMK1%0'  ' DUSP1_g%0')  (' LIMK1%0'  ' MSK_f%0')  (' LIMK1%0'  ' GRAP2%0')  (' LIMK1%0'  ' TAB_f%0')  (' LIMK1%0'  ' ATF2%0')  (' LIMK1%0'  ' SMAD5%0')  (' LIMK1%0'  ' SMAD1%0')  (' LIMK1%0'  ' FOS%0')  (' LIMK1%0'  ' JUN%0')  (' LIMK1%0'  ' MAP3K7%0')  (' LIMK1%0'  ' NLK%0')  (' LIMK1%0'  ' SMAD7_g%0')  (' LIMK1%0'  ' SMAD6_g%0')  (' LIMK1%0'  ' AP1_c%0')  (' LIMK1%0'  ' ACVR1%0')  (' LIMK1%0'  ' PTPN6%0')  (' LIMK1%0'  ' CDC42%0')  (' LIMK1%0'  ' GRB2%0')  (' LIMK1%0'  ' TGFBR1%0')  (' LIMK1%0'  ' SMURF1%0')  (' LIMK1%0'  ' SMURF2%0')  (' LIMK1%0'  ' RHOA%0')  (' LIMK1%0'  ' BMPR2%0')  (' LIMK1%0'  ' PARD6A%0')  (' LIMK1%0'  ' DAAM1%0')  (' LIMK1%0'  ' SFRP1_g%0')  (' LIMK1%0'  ' PPM1A%0')  (' LIMK1%0'  ' CFL_f%0')  (' LIMK1%0'  ' PAK1%0')  (' LIMK1%0'  ' MAP3K11%0')  (' LIMK1%0'  ' MAP3K4%0')  (' LIMK1%0'  ' ROCK1%0')  (' LIMK1%0'  ' ITCH%0')  (' LIMK1%0'  ' ARHGAP24%0')  (' LIMK1%0'  ' TIAM1%0')  (' LIMK1%0'  ' RND3%0')  (' LIMK1%0'  ' MAPK8IP3%0')  (' LIMK1%0'  ' MXD1%0')  (' LIMK1%0'  ' PIP3%0')  (' ROCK1%0'  ' SRC%0')  (' ROCK1%0'  ' CSK%0')  (' ROCK1%0'  ' CHUK%0')  (' ROCK1%0'  ' RAC_f%0')  (' ROCK1%0'  ' DUSP1%0')  (' ROCK1%0'  ' TGFBR2%0')  (' ROCK1%0'  ' ILR_f%0')  (' ROCK1%0'  ' SYK%0')  (' ROCK1%0'  ' IRAK1%0')  (' ROCK1%0'  ' SHC1%0')  (' ROCK1%0'  ' JAK_f%0')  (' ROCK1%0'  ' CBPp300_c%0')  (' ROCK1%0'  ' SKP2%0')  (' ROCK1%0'  ' TP53%0')  (' ROCK1%0'  ' SMAD7%0')  (' ROCK1%0'  ' SMAD6%0')  (' ROCK1%0'  ' DKK_f%0')  (' ROCK1%0'  ' FOXO_f%0')  (' ROCK1%0'  ' TCF7_f%0')  (' ROCK1%0'  ' DKK_g%0')  (' ROCK1%0'  ' MYC%0')  (' ROCK1%0'  ' CCND1%0')  (' ROCK1%0'  ' EGR1%0')  (' ROCK1%0'  ' MMP_f%0')  (' ROCK1%0'  ' PTEN_g%0')  (' ROCK1%0'  ' RTPK_f%0')  (' ROCK1%0'  ' CTNNB1%0')  (' ROCK1%0'  'LEF1%0')  (' ROCK1%0'  'SFRP1%0')  (' ROCK1%0'  'FZD_f%0')  (' ROCK1%0'  ' CASP8%0')  (' ROCK1%0'  ' REL_f%0')  (' ROCK1%0'  ' NFKB_f%0')  (' ROCK1%0'  ' DVL_f%0')  (' ROCK1%0'  ' LRP_f%0')  (' ROCK1%0'  ' BTRC%0')  (' ROCK1%0'  ' CK1_f%0')  (' ROCK1%0'  ' AXIN1%0')  (' ROCK1%0'  ' mTORC2_c%0')  (' ROCK1%0'  ' PDPK1%0')  (' ROCK1%0'  ' MEK_f%0')  (' ROCK1%0'  ' CYCS%0')  (' ROCK1%0'  ' CASP9%0')  (' ROCK1%0'  ' GSK3_f%0')  (' ROCK1%0'  ' IRS1%0')  (' ROCK1%0'  ' MDM2%0')  (' ROCK1%0'  ' AKT_f%0')  (' ROCK1%0'  ' BCL2%0')  (' ROCK1%0'  ' RAF_f%0')  (' ROCK1%0'  ' mTORC1_c%0')  (' ROCK1%0'  ' RHEB%0')  (' ROCK1%0'  ' RTPK_g%0')  (' ROCK1%0'  ' PTEN%0')  (' ROCK1%0'  ' CASP3%0')  (' ROCK1%0'  ' PIK3CA%0')  (' ROCK1%0'  ' CREBBP%0')  (' ROCK1%0'  ' PTPN11%0')  (' ROCK1%0'  ' KRAS%0')  (' ROCK1%0'  ' MAP2K4%0')  (' ROCK1%0'  ' MAP2K7%0')  (' ROCK1%0'  ' MAPK14%0')  (' ROCK1%0'  ' JNK_f%0')  (' ROCK1%0'  ' MAP2K3%0')  (' ROCK1%0'  ' ERK_f%0')  (' ROCK1%0'  ' LIF%0')  (' ROCK1%0'  ' PPP1CA%0')  (' ROCK1%0'  ' GAB_f%0')  (' ROCK1%0'  ' SOS1%0')  (' ROCK1%0'  ' PRKCA%0')  (' ROCK1%0'  ' VAV1%0')  (' ROCK1%0'  ' PLCG1%0')  (' ROCK1%0'  ' PRKCD%0')  (' ROCK1%0'  ' RSK_f%0')  (' ROCK1%0'  ' S6K_f%0')  (' ROCK1%0'  ' PLK1%0')  (' ROCK1%0'  ' ILK%0')  (' ROCK1%0'  ' SOCS1%0')  (' ROCK1%0'  ' DUSP6%0')  (' ROCK1%0'  ' STAT3%0')  (' ROCK1%0'  ' LIMK2%0')  (' ROCK1%0'  ' EP300%0')  (' ROCK1%0'  ' STAT1%0')  (' ROCK1%0'  ' IKBKB%0')  (' ROCK1%0'  ' SRF%0')  (' ROCK1%0'  ' PIAS1%0')  (' ROCK1%0'  ' TRAF6%0')  (' ROCK1%0'  ' SOCS1_g%0')  (' ROCK1%0'  ' ISGF3_c%0')  (' ROCK1%0'  ' STAT2%0')  (' ROCK1%0'  ' CFLAR%0')  (' ROCK1%0'  ' SMAD2%0')  (' ROCK1%0'  ' MDM2_g%0')  (' ROCK1%0'  ' BAX%0')  (' ROCK1%0'  ' PRKACA%0')  (' ROCK1%0'  ' TGFB1%0')  (' ROCK1%0'  ' MAP3K8%0')  (' ROCK1%0'  ' TSC_f%0')  (' ROCK1%0'  ' SMAD4%0')  (' ROCK1%0'  ' BAD%0')  (' ROCK1%0'  ' MAP3K5%0')  (' ROCK1%0'  ' AKT1S1%0')  (' ROCK1%0'  ' SKI%0')  (' ROCK1%0'  ' SMAD3%0')  (' ROCK1%0'  ' MAPKAPK2%0')  (' ROCK1%0'  ' DUSP1_g%0')  (' ROCK1%0'  ' MSK_f%0')  (' ROCK1%0'  ' GRAP2%0')  (' ROCK1%0'  ' TAB_f%0')  (' ROCK1%0'  ' ATF2%0')  (' ROCK1%0'  ' SMAD5%0')  (' ROCK1%0'  ' SMAD1%0')  (' ROCK1%0'  ' FOS%0')  (' ROCK1%0'  ' JUN%0')  (' ROCK1%0'  ' MAP3K7%0')  (' ROCK1%0'  ' NLK%0')  (' ROCK1%0'  ' SMAD7_g%0')  (' ROCK1%0'  ' SMAD6_g%0')  (' ROCK1%0'  ' AP1_c%0')  (' ROCK1%0'  ' ACVR1%0')  (' ROCK1%0'  ' PTPN6%0')  (' ROCK1%0'  ' CDC42%0')  (' ROCK1%0'  ' GRB2%0')  (' ROCK1%0'  ' TGFBR1%0')  (' ROCK1%0'  ' SMURF1%0')  (' ROCK1%0'  ' SMURF2%0')  (' ROCK1%0'  ' RHOA%0')  (' ROCK1%0'  ' BMPR2%0')  (' ROCK1%0'  ' PARD6A%0')  (' ROCK1%0'  ' DAAM1%0')  (' ROCK1%0'  ' SFRP1_g%0')  (' ROCK1%0'  ' PPM1A%0')  (' ROCK1%0'  ' CFL_f%0')  (' ROCK1%0'  ' PAK1%0')  (' ROCK1%0'  ' MAP3K11%0')  (' ROCK1%0'  ' MAP3K4%0')  (' ROCK1%0'  ' LIMK1%0')  (' ROCK1%0'  ' ITCH%0')  (' ROCK1%0'  ' ARHGAP24%0')  (' ROCK1%0'  ' TIAM1%0')  (' ROCK1%0'  ' RND3%0')  (' ROCK1%0'  ' MAPK8IP3%0')  (' ROCK1%0'  ' MXD1%0')  (' ROCK1%0'  ' PIP3%0')  (' ITCH%0'  ' SRC%0')  (' ITCH%0'  ' CSK%0')  (' ITCH%0'  ' CHUK%0')  (' ITCH%0'  ' RAC_f%0')  (' ITCH%0'  ' DUSP1%0')  (' ITCH%0'  ' TGFBR2%0')  (' ITCH%0'  ' ILR_f%0')  (' ITCH%0'  ' SYK%0')  (' ITCH%0'  ' IRAK1%0')  (' ITCH%0'  ' SHC1%0')  (' ITCH%0'  ' JAK_f%0')  (' ITCH%0'  ' CBPp300_c%0')  (' ITCH%0'  ' SKP2%0')  (' ITCH%0'  ' TP53%0')  (' ITCH%0'  ' SMAD7%0')  (' ITCH%0'  ' SMAD6%0')  (' ITCH%0'  ' DKK_f%0')  (' ITCH%0'  ' FOXO_f%0')  (' ITCH%0'  ' TCF7_f%0')  (' ITCH%0'  ' DKK_g%0')  (' ITCH%0'  ' MYC%0')  (' ITCH%0'  ' CCND1%0')  (' ITCH%0'  ' EGR1%0')  (' ITCH%0'  ' MMP_f%0')  (' ITCH%0'  ' PTEN_g%0')  (' ITCH%0'  ' RTPK_f%0')  (' ITCH%0'  ' CTNNB1%0')  (' ITCH%0'  'LEF1%0')  (' ITCH%0'  'SFRP1%0')  (' ITCH%0'  'FZD_f%0')  (' ITCH%0'  ' CASP8%0')  (' ITCH%0'  ' REL_f%0')  (' ITCH%0'  ' NFKB_f%0')  (' ITCH%0'  ' DVL_f%0')  (' ITCH%0'  ' LRP_f%0')  (' ITCH%0'  ' BTRC%0')  (' ITCH%0'  ' CK1_f%0')  (' ITCH%0'  ' AXIN1%0')  (' ITCH%0'  ' mTORC2_c%0')  (' ITCH%0'  ' PDPK1%0')  (' ITCH%0'  ' MEK_f%0')  (' ITCH%0'  ' CYCS%0')  (' ITCH%0'  ' CASP9%0')  (' ITCH%0'  ' GSK3_f%0')  (' ITCH%0'  ' IRS1%0')  (' ITCH%0'  ' MDM2%0')  (' ITCH%0'  ' AKT_f%0')  (' ITCH%0'  ' BCL2%0')  (' ITCH%0'  ' RAF_f%0')  (' ITCH%0'  ' mTORC1_c%0')  (' ITCH%0'  ' RHEB%0')  (' ITCH%0'  ' RTPK_g%0')  (' ITCH%0'  ' PTEN%0')  (' ITCH%0'  ' CASP3%0')  (' ITCH%0'  ' PIK3CA%0')  (' ITCH%0'  ' CREBBP%0')  (' ITCH%0'  ' PTPN11%0')  (' ITCH%0'  ' KRAS%0')  (' ITCH%0'  ' MAP2K4%0')  (' ITCH%0'  ' MAP2K7%0')  (' ITCH%0'  ' MAPK14%0')  (' ITCH%0'  ' JNK_f%0')  (' ITCH%0'  ' MAP2K3%0')  (' ITCH%0'  ' ERK_f%0')  (' ITCH%0'  ' LIF%0')  (' ITCH%0'  ' PPP1CA%0')  (' ITCH%0'  ' GAB_f%0')  (' ITCH%0'  ' SOS1%0')  (' ITCH%0'  ' PRKCA%0')  (' ITCH%0'  ' VAV1%0')  (' ITCH%0'  ' PLCG1%0')  (' ITCH%0'  ' PRKCD%0')  (' ITCH%0'  ' RSK_f%0')  (' ITCH%0'  ' S6K_f%0')  (' ITCH%0'  ' PLK1%0')  (' ITCH%0'  ' ILK%0')  (' ITCH%0'  ' SOCS1%0')  (' ITCH%0'  ' DUSP6%0')  (' ITCH%0'  ' STAT3%0')  (' ITCH%0'  ' LIMK2%0')  (' ITCH%0'  ' EP300%0')  (' ITCH%0'  ' STAT1%0')  (' ITCH%0'  ' IKBKB%0')  (' ITCH%0'  ' SRF%0')  (' ITCH%0'  ' PIAS1%0')  (' ITCH%0'  ' TRAF6%0')  (' ITCH%0'  ' SOCS1_g%0')  (' ITCH%0'  ' ISGF3_c%0')  (' ITCH%0'  ' STAT2%0')  (' ITCH%0'  ' CFLAR%0')  (' ITCH%0'  ' SMAD2%0')  (' ITCH%0'  ' MDM2_g%0')  (' ITCH%0'  ' BAX%0')  (' ITCH%0'  ' PRKACA%0')  (' ITCH%0'  ' TGFB1%0')  (' ITCH%0'  ' MAP3K8%0')  (' ITCH%0'  ' TSC_f%0')  (' ITCH%0'  ' SMAD4%0')  (' ITCH%0'  ' BAD%0')  (' ITCH%0'  ' MAP3K5%0')  (' ITCH%0'  ' AKT1S1%0')  (' ITCH%0'  ' SKI%0')  (' ITCH%0'  ' SMAD3%0')  (' ITCH%0'  ' MAPKAPK2%0')  (' ITCH%0'  ' DUSP1_g%0')  (' ITCH%0'  ' MSK_f%0')  (' ITCH%0'  ' GRAP2%0')  (' ITCH%0'  ' TAB_f%0')  (' ITCH%0'  ' ATF2%0')  (' ITCH%0'  ' SMAD5%0')  (' ITCH%0'  ' SMAD1%0')  (' ITCH%0'  ' FOS%0')  (' ITCH%0'  ' JUN%0')  (' ITCH%0'  ' MAP3K7%0')  (' ITCH%0'  ' NLK%0')  (' ITCH%0'  ' SMAD7_g%0')  (' ITCH%0'  ' SMAD6_g%0')  (' ITCH%0'  ' AP1_c%0')  (' ITCH%0'  ' ACVR1%0')  (' ITCH%0'  ' PTPN6%0')  (' ITCH%0'  ' CDC42%0')  (' ITCH%0'  ' GRB2%0')  (' ITCH%0'  ' TGFBR1%0')  (' ITCH%0'  ' SMURF1%0')  (' ITCH%0'  ' SMURF2%0')  (' ITCH%0'  ' RHOA%0')  (' ITCH%0'  ' BMPR2%0')  (' ITCH%0'  ' PARD6A%0')  (' ITCH%0'  ' DAAM1%0')  (' ITCH%0'  ' SFRP1_g%0')  (' ITCH%0'  ' PPM1A%0')  (' ITCH%0'  ' CFL_f%0')  (' ITCH%0'  ' PAK1%0')  (' ITCH%0'  ' MAP3K11%0')  (' ITCH%0'  ' MAP3K4%0')  (' ITCH%0'  ' LIMK1%0')  (' ITCH%0'  ' ROCK1%0')  (' ITCH%0'  ' ARHGAP24%0')  (' ITCH%0'  ' TIAM1%0')  (' ITCH%0'  ' RND3%0')  (' ITCH%0'  ' MAPK8IP3%0')  (' ITCH%0'  ' MXD1%0')  (' ITCH%0'  ' PIP3%0')  (' ARHGAP24%0'  ' SRC%0')  (' ARHGAP24%0'  ' CSK%0')  (' ARHGAP24%0'  ' CHUK%0')  (' ARHGAP24%0'  ' RAC_f%0')  (' ARHGAP24%0'  ' DUSP1%0')  (' ARHGAP24%0'  ' TGFBR2%0')  (' ARHGAP24%0'  ' ILR_f%0')  (' ARHGAP24%0'  ' SYK%0')  (' ARHGAP24%0'  ' IRAK1%0')  (' ARHGAP24%0'  ' SHC1%0')  (' ARHGAP24%0'  ' JAK_f%0')  (' ARHGAP24%0'  ' CBPp300_c%0')  (' ARHGAP24%0'  ' SKP2%0')  (' ARHGAP24%0'  ' TP53%0')  (' ARHGAP24%0'  ' SMAD7%0')  (' ARHGAP24%0'  ' SMAD6%0')  (' ARHGAP24%0'  ' DKK_f%0')  (' ARHGAP24%0'  ' FOXO_f%0')  (' ARHGAP24%0'  ' TCF7_f%0')  (' ARHGAP24%0'  ' DKK_g%0')  (' ARHGAP24%0'  ' MYC%0')  (' ARHGAP24%0'  ' CCND1%0')  (' ARHGAP24%0'  ' EGR1%0')  (' ARHGAP24%0'  ' MMP_f%0')  (' ARHGAP24%0'  ' PTEN_g%0')  (' ARHGAP24%0'  ' RTPK_f%0')  (' ARHGAP24%0'  ' CTNNB1%0')  (' ARHGAP24%0'  'LEF1%0')  (' ARHGAP24%0'  'SFRP1%0')  (' ARHGAP24%0'  'FZD_f%0')  (' ARHGAP24%0'  ' CASP8%0')  (' ARHGAP24%0'  ' REL_f%0')  (' ARHGAP24%0'  ' NFKB_f%0')  (' ARHGAP24%0'  ' DVL_f%0')  (' ARHGAP24%0'  ' LRP_f%0')  (' ARHGAP24%0'  ' BTRC%0')  (' ARHGAP24%0'  ' CK1_f%0')  (' ARHGAP24%0'  ' AXIN1%0')  (' ARHGAP24%0'  ' mTORC2_c%0')  (' ARHGAP24%0'  ' PDPK1%0')  (' ARHGAP24%0'  ' MEK_f%0')  (' ARHGAP24%0'  ' CYCS%0')  (' ARHGAP24%0'  ' CASP9%0')  (' ARHGAP24%0'  ' GSK3_f%0')  (' ARHGAP24%0'  ' IRS1%0')  (' ARHGAP24%0'  ' MDM2%0')  (' ARHGAP24%0'  ' AKT_f%0')  (' ARHGAP24%0'  ' BCL2%0')  (' ARHGAP24%0'  ' RAF_f%0')  (' ARHGAP24%0'  ' mTORC1_c%0')  (' ARHGAP24%0'  ' RHEB%0')  (' ARHGAP24%0'  ' RTPK_g%0')  (' ARHGAP24%0'  ' PTEN%0')  (' ARHGAP24%0'  ' CASP3%0')  (' ARHGAP24%0'  ' PIK3CA%0')  (' ARHGAP24%0'  ' CREBBP%0')  (' ARHGAP24%0'  ' PTPN11%0')  (' ARHGAP24%0'  ' KRAS%0')  (' ARHGAP24%0'  ' MAP2K4%0')  (' ARHGAP24%0'  ' MAP2K7%0')  (' ARHGAP24%0'  ' MAPK14%0')  (' ARHGAP24%0'  ' JNK_f%0')  (' ARHGAP24%0'  ' MAP2K3%0')  (' ARHGAP24%0'  ' ERK_f%0')  (' ARHGAP24%0'  ' LIF%0')  (' ARHGAP24%0'  ' PPP1CA%0')  (' ARHGAP24%0'  ' GAB_f%0')  (' ARHGAP24%0'  ' SOS1%0')  (' ARHGAP24%0'  ' PRKCA%0')  (' ARHGAP24%0'  ' VAV1%0')  (' ARHGAP24%0'  ' PLCG1%0')  (' ARHGAP24%0'  ' PRKCD%0')  (' ARHGAP24%0'  ' RSK_f%0')  (' ARHGAP24%0'  ' S6K_f%0')  (' ARHGAP24%0'  ' PLK1%0')  (' ARHGAP24%0'  ' ILK%0')  (' ARHGAP24%0'  ' SOCS1%0')  (' ARHGAP24%0'  ' DUSP6%0')  (' ARHGAP24%0'  ' STAT3%0')  (' ARHGAP24%0'  ' LIMK2%0')  (' ARHGAP24%0'  ' EP300%0')  (' ARHGAP24%0'  ' STAT1%0')  (' ARHGAP24%0'  ' IKBKB%0')  (' ARHGAP24%0'  ' SRF%0')  (' ARHGAP24%0'  ' PIAS1%0')  (' ARHGAP24%0'  ' TRAF6%0')  (' ARHGAP24%0'  ' SOCS1_g%0')  (' ARHGAP24%0'  ' ISGF3_c%0')  (' ARHGAP24%0'  ' STAT2%0')  (' ARHGAP24%0'  ' CFLAR%0')  (' ARHGAP24%0'  ' SMAD2%0')  (' ARHGAP24%0'  ' MDM2_g%0')  (' ARHGAP24%0'  ' BAX%0')  (' ARHGAP24%0'  ' PRKACA%0')  (' ARHGAP24%0'  ' TGFB1%0')  (' ARHGAP24%0'  ' MAP3K8%0')  (' ARHGAP24%0'  ' TSC_f%0')  (' ARHGAP24%0'  ' SMAD4%0')  (' ARHGAP24%0'  ' BAD%0')  (' ARHGAP24%0'  ' MAP3K5%0')  (' ARHGAP24%0'  ' AKT1S1%0')  (' ARHGAP24%0'  ' SKI%0')  (' ARHGAP24%0'  ' SMAD3%0')  (' ARHGAP24%0'  ' MAPKAPK2%0')  (' ARHGAP24%0'  ' DUSP1_g%0')  (' ARHGAP24%0'  ' MSK_f%0')  (' ARHGAP24%0'  ' GRAP2%0')  (' ARHGAP24%0'  ' TAB_f%0')  (' ARHGAP24%0'  ' ATF2%0')  (' ARHGAP24%0'  ' SMAD5%0')  (' ARHGAP24%0'  ' SMAD1%0')  (' ARHGAP24%0'  ' FOS%0')  (' ARHGAP24%0'  ' JUN%0')  (' ARHGAP24%0'  ' MAP3K7%0')  (' ARHGAP24%0'  ' NLK%0')  (' ARHGAP24%0'  ' SMAD7_g%0')  (' ARHGAP24%0'  ' SMAD6_g%0')  (' ARHGAP24%0'  ' AP1_c%0')  (' ARHGAP24%0'  ' ACVR1%0')  (' ARHGAP24%0'  ' PTPN6%0')  (' ARHGAP24%0'  ' CDC42%0')  (' ARHGAP24%0'  ' GRB2%0')  (' ARHGAP24%0'  ' TGFBR1%0')  (' ARHGAP24%0'  ' SMURF1%0')  (' ARHGAP24%0'  ' SMURF2%0')  (' ARHGAP24%0'  ' RHOA%0')  (' ARHGAP24%0'  ' BMPR2%0')  (' ARHGAP24%0'  ' PARD6A%0')  (' ARHGAP24%0'  ' DAAM1%0')  (' ARHGAP24%0'  ' SFRP1_g%0')  (' ARHGAP24%0'  ' PPM1A%0')  (' ARHGAP24%0'  ' CFL_f%0')  (' ARHGAP24%0'  ' PAK1%0')  (' ARHGAP24%0'  ' MAP3K11%0')  (' ARHGAP24%0'  ' MAP3K4%0')  (' ARHGAP24%0'  ' LIMK1%0')  (' ARHGAP24%0'  ' ROCK1%0')  (' ARHGAP24%0'  ' ITCH%0')  (' ARHGAP24%0'  ' TIAM1%0')  (' ARHGAP24%0'  ' RND3%0')  (' ARHGAP24%0'  ' MAPK8IP3%0')  (' ARHGAP24%0'  ' MXD1%0')  (' ARHGAP24%0'  ' PIP3%0')  (' TIAM1%0'  ' SRC%0')  (' TIAM1%0'  ' CSK%0')  (' TIAM1%0'  ' CHUK%0')  (' TIAM1%0'  ' RAC_f%0')  (' TIAM1%0'  ' DUSP1%0')  (' TIAM1%0'  ' TGFBR2%0')  (' TIAM1%0'  ' ILR_f%0')  (' TIAM1%0'  ' SYK%0')  (' TIAM1%0'  ' IRAK1%0')  (' TIAM1%0'  ' SHC1%0')  (' TIAM1%0'  ' JAK_f%0')  (' TIAM1%0'  ' CBPp300_c%0')  (' TIAM1%0'  ' SKP2%0')  (' TIAM1%0'  ' TP53%0')  (' TIAM1%0'  ' SMAD7%0')  (' TIAM1%0'  ' SMAD6%0')  (' TIAM1%0'  ' DKK_f%0')  (' TIAM1%0'  ' FOXO_f%0')  (' TIAM1%0'  ' TCF7_f%0')  (' TIAM1%0'  ' DKK_g%0')  (' TIAM1%0'  ' MYC%0')  (' TIAM1%0'  ' CCND1%0')  (' TIAM1%0'  ' EGR1%0')  (' TIAM1%0'  ' MMP_f%0')  (' TIAM1%0'  ' PTEN_g%0')  (' TIAM1%0'  ' RTPK_f%0')  (' TIAM1%0'  ' CTNNB1%0')  (' TIAM1%0'  'LEF1%0')  (' TIAM1%0'  'SFRP1%0')  (' TIAM1%0'  'FZD_f%0')  (' TIAM1%0'  ' CASP8%0')  (' TIAM1%0'  ' REL_f%0')  (' TIAM1%0'  ' NFKB_f%0')  (' TIAM1%0'  ' DVL_f%0')  (' TIAM1%0'  ' LRP_f%0')  (' TIAM1%0'  ' BTRC%0')  (' TIAM1%0'  ' CK1_f%0')  (' TIAM1%0'  ' AXIN1%0')  (' TIAM1%0'  ' mTORC2_c%0')  (' TIAM1%0'  ' PDPK1%0')  (' TIAM1%0'  ' MEK_f%0')  (' TIAM1%0'  ' CYCS%0')  (' TIAM1%0'  ' CASP9%0')  (' TIAM1%0'  ' GSK3_f%0')  (' TIAM1%0'  ' IRS1%0')  (' TIAM1%0'  ' MDM2%0')  (' TIAM1%0'  ' AKT_f%0')  (' TIAM1%0'  ' BCL2%0')  (' TIAM1%0'  ' RAF_f%0')  (' TIAM1%0'  ' mTORC1_c%0')  (' TIAM1%0'  ' RHEB%0')  (' TIAM1%0'  ' RTPK_g%0')  (' TIAM1%0'  ' PTEN%0')  (' TIAM1%0'  ' CASP3%0')  (' TIAM1%0'  ' PIK3CA%0')  (' TIAM1%0'  ' CREBBP%0')  (' TIAM1%0'  ' PTPN11%0')  (' TIAM1%0'  ' KRAS%0')  (' TIAM1%0'  ' MAP2K4%0')  (' TIAM1%0'  ' MAP2K7%0')  (' TIAM1%0'  ' MAPK14%0')  (' TIAM1%0'  ' JNK_f%0')  (' TIAM1%0'  ' MAP2K3%0')  (' TIAM1%0'  ' ERK_f%0')  (' TIAM1%0'  ' LIF%0')  (' TIAM1%0'  ' PPP1CA%0')  (' TIAM1%0'  ' GAB_f%0')  (' TIAM1%0'  ' SOS1%0')  (' TIAM1%0'  ' PRKCA%0')  (' TIAM1%0'  ' VAV1%0')  (' TIAM1%0'  ' PLCG1%0')  (' TIAM1%0'  ' PRKCD%0')  (' TIAM1%0'  ' RSK_f%0')  (' TIAM1%0'  ' S6K_f%0')  (' TIAM1%0'  ' PLK1%0')  (' TIAM1%0'  ' ILK%0')  (' TIAM1%0'  ' SOCS1%0')  (' TIAM1%0'  ' DUSP6%0')  (' TIAM1%0'  ' STAT3%0')  (' TIAM1%0'  ' LIMK2%0')  (' TIAM1%0'  ' EP300%0')  (' TIAM1%0'  ' STAT1%0')  (' TIAM1%0'  ' IKBKB%0')  (' TIAM1%0'  ' SRF%0')  (' TIAM1%0'  ' PIAS1%0')  (' TIAM1%0'  ' TRAF6%0')  (' TIAM1%0'  ' SOCS1_g%0')  (' TIAM1%0'  ' ISGF3_c%0')  (' TIAM1%0'  ' STAT2%0')  (' TIAM1%0'  ' CFLAR%0')  (' TIAM1%0'  ' SMAD2%0')  (' TIAM1%0'  ' MDM2_g%0')  (' TIAM1%0'  ' BAX%0')  (' TIAM1%0'  ' PRKACA%0')  (' TIAM1%0'  ' TGFB1%0')  (' TIAM1%0'  ' MAP3K8%0')  (' TIAM1%0'  ' TSC_f%0')  (' TIAM1%0'  ' SMAD4%0')  (' TIAM1%0'  ' BAD%0')  (' TIAM1%0'  ' MAP3K5%0')  (' TIAM1%0'  ' AKT1S1%0')  (' TIAM1%0'  ' SKI%0')  (' TIAM1%0'  ' SMAD3%0')  (' TIAM1%0'  ' MAPKAPK2%0')  (' TIAM1%0'  ' DUSP1_g%0')  (' TIAM1%0'  ' MSK_f%0')  (' TIAM1%0'  ' GRAP2%0')  (' TIAM1%0'  ' TAB_f%0')  (' TIAM1%0'  ' ATF2%0')  (' TIAM1%0'  ' SMAD5%0')  (' TIAM1%0'  ' SMAD1%0')  (' TIAM1%0'  ' FOS%0')  (' TIAM1%0'  ' JUN%0')  (' TIAM1%0'  ' MAP3K7%0')  (' TIAM1%0'  ' NLK%0')  (' TIAM1%0'  ' SMAD7_g%0')  (' TIAM1%0'  ' SMAD6_g%0')  (' TIAM1%0'  ' AP1_c%0')  (' TIAM1%0'  ' ACVR1%0')  (' TIAM1%0'  ' PTPN6%0')  (' TIAM1%0'  ' CDC42%0')  (' TIAM1%0'  ' GRB2%0')  (' TIAM1%0'  ' TGFBR1%0')  (' TIAM1%0'  ' SMURF1%0')  (' TIAM1%0'  ' SMURF2%0')  (' TIAM1%0'  ' RHOA%0')  (' TIAM1%0'  ' BMPR2%0')  (' TIAM1%0'  ' PARD6A%0')  (' TIAM1%0'  ' DAAM1%0')  (' TIAM1%0'  ' SFRP1_g%0')  (' TIAM1%0'  ' PPM1A%0')  (' TIAM1%0'  ' CFL_f%0')  (' TIAM1%0'  ' PAK1%0')  (' TIAM1%0'  ' MAP3K11%0')  (' TIAM1%0'  ' MAP3K4%0')  (' TIAM1%0'  ' LIMK1%0')  (' TIAM1%0'  ' ROCK1%0')  (' TIAM1%0'  ' ITCH%0')  (' TIAM1%0'  ' ARHGAP24%0')  (' TIAM1%0'  ' RND3%0')  (' TIAM1%0'  ' MAPK8IP3%0')  (' TIAM1%0'  ' MXD1%0')  (' TIAM1%0'  ' PIP3%0')  (' RND3%0'  ' SRC%0')  (' RND3%0'  ' CSK%0')  (' RND3%0'  ' CHUK%0')  (' RND3%0'  ' RAC_f%0')  (' RND3%0'  ' DUSP1%0')  (' RND3%0'  ' TGFBR2%0')  (' RND3%0'  ' ILR_f%0')  (' RND3%0'  ' SYK%0')  (' RND3%0'  ' IRAK1%0')  (' RND3%0'  ' SHC1%0')  (' RND3%0'  ' JAK_f%0')  (' RND3%0'  ' CBPp300_c%0')  (' RND3%0'  ' SKP2%0')  (' RND3%0'  ' TP53%0')  (' RND3%0'  ' SMAD7%0')  (' RND3%0'  ' SMAD6%0')  (' RND3%0'  ' DKK_f%0')  (' RND3%0'  ' FOXO_f%0')  (' RND3%0'  ' TCF7_f%0')  (' RND3%0'  ' DKK_g%0')  (' RND3%0'  ' MYC%0')  (' RND3%0'  ' CCND1%0')  (' RND3%0'  ' EGR1%0')  (' RND3%0'  ' MMP_f%0')  (' RND3%0'  ' PTEN_g%0')  (' RND3%0'  ' RTPK_f%0')  (' RND3%0'  ' CTNNB1%0')  (' RND3%0'  'LEF1%0')  (' RND3%0'  'SFRP1%0')  (' RND3%0'  'FZD_f%0')  (' RND3%0'  ' CASP8%0')  (' RND3%0'  ' REL_f%0')  (' RND3%0'  ' NFKB_f%0')  (' RND3%0'  ' DVL_f%0')  (' RND3%0'  ' LRP_f%0')  (' RND3%0'  ' BTRC%0')  (' RND3%0'  ' CK1_f%0')  (' RND3%0'  ' AXIN1%0')  (' RND3%0'  ' mTORC2_c%0')  (' RND3%0'  ' PDPK1%0')  (' RND3%0'  ' MEK_f%0')  (' RND3%0'  ' CYCS%0')  (' RND3%0'  ' CASP9%0')  (' RND3%0'  ' GSK3_f%0')  (' RND3%0'  ' IRS1%0')  (' RND3%0'  ' MDM2%0')  (' RND3%0'  ' AKT_f%0')  (' RND3%0'  ' BCL2%0')  (' RND3%0'  ' RAF_f%0')  (' RND3%0'  ' mTORC1_c%0')  (' RND3%0'  ' RHEB%0')  (' RND3%0'  ' RTPK_g%0')  (' RND3%0'  ' PTEN%0')  (' RND3%0'  ' CASP3%0')  (' RND3%0'  ' PIK3CA%0')  (' RND3%0'  ' CREBBP%0')  (' RND3%0'  ' PTPN11%0')  (' RND3%0'  ' KRAS%0')  (' RND3%0'  ' MAP2K4%0')  (' RND3%0'  ' MAP2K7%0')  (' RND3%0'  ' MAPK14%0')  (' RND3%0'  ' JNK_f%0')  (' RND3%0'  ' MAP2K3%0')  (' RND3%0'  ' ERK_f%0')  (' RND3%0'  ' LIF%0')  (' RND3%0'  ' PPP1CA%0')  (' RND3%0'  ' GAB_f%0')  (' RND3%0'  ' SOS1%0')  (' RND3%0'  ' PRKCA%0')  (' RND3%0'  ' VAV1%0')  (' RND3%0'  ' PLCG1%0')  (' RND3%0'  ' PRKCD%0')  (' RND3%0'  ' RSK_f%0')  (' RND3%0'  ' S6K_f%0')  (' RND3%0'  ' PLK1%0')  (' RND3%0'  ' ILK%0')  (' RND3%0'  ' SOCS1%0')  (' RND3%0'  ' DUSP6%0')  (' RND3%0'  ' STAT3%0')  (' RND3%0'  ' LIMK2%0')  (' RND3%0'  ' EP300%0')  (' RND3%0'  ' STAT1%0')  (' RND3%0'  ' IKBKB%0')  (' RND3%0'  ' SRF%0')  (' RND3%0'  ' PIAS1%0')  (' RND3%0'  ' TRAF6%0')  (' RND3%0'  ' SOCS1_g%0')  (' RND3%0'  ' ISGF3_c%0')  (' RND3%0'  ' STAT2%0')  (' RND3%0'  ' CFLAR%0')  (' RND3%0'  ' SMAD2%0')  (' RND3%0'  ' MDM2_g%0')  (' RND3%0'  ' BAX%0')  (' RND3%0'  ' PRKACA%0')  (' RND3%0'  ' TGFB1%0')  (' RND3%0'  ' MAP3K8%0')  (' RND3%0'  ' TSC_f%0')  (' RND3%0'  ' SMAD4%0')  (' RND3%0'  ' BAD%0')  (' RND3%0'  ' MAP3K5%0')  (' RND3%0'  ' AKT1S1%0')  (' RND3%0'  ' SKI%0')  (' RND3%0'  ' SMAD3%0')  (' RND3%0'  ' MAPKAPK2%0')  (' RND3%0'  ' DUSP1_g%0')  (' RND3%0'  ' MSK_f%0')  (' RND3%0'  ' GRAP2%0')  (' RND3%0'  ' TAB_f%0')  (' RND3%0'  ' ATF2%0')  (' RND3%0'  ' SMAD5%0')  (' RND3%0'  ' SMAD1%0')  (' RND3%0'  ' FOS%0')  (' RND3%0'  ' JUN%0')  (' RND3%0'  ' MAP3K7%0')  (' RND3%0'  ' NLK%0')  (' RND3%0'  ' SMAD7_g%0')  (' RND3%0'  ' SMAD6_g%0')  (' RND3%0'  ' AP1_c%0')  (' RND3%0'  ' ACVR1%0')  (' RND3%0'  ' PTPN6%0')  (' RND3%0'  ' CDC42%0')  (' RND3%0'  ' GRB2%0')  (' RND3%0'  ' TGFBR1%0')  (' RND3%0'  ' SMURF1%0')  (' RND3%0'  ' SMURF2%0')  (' RND3%0'  ' RHOA%0')  (' RND3%0'  ' BMPR2%0')  (' RND3%0'  ' PARD6A%0')  (' RND3%0'  ' DAAM1%0')  (' RND3%0'  ' SFRP1_g%0')  (' RND3%0'  ' PPM1A%0')  (' RND3%0'  ' CFL_f%0')  (' RND3%0'  ' PAK1%0')  (' RND3%0'  ' MAP3K11%0')  (' RND3%0'  ' MAP3K4%0')  (' RND3%0'  ' LIMK1%0')  (' RND3%0'  ' ROCK1%0')  (' RND3%0'  ' ITCH%0')  (' RND3%0'  ' ARHGAP24%0')  (' RND3%0'  ' TIAM1%0')  (' RND3%0'  ' MAPK8IP3%0')  (' RND3%0'  ' MXD1%0')  (' RND3%0'  ' PIP3%0')  (' MAPK8IP3%0'  ' SRC%0')  (' MAPK8IP3%0'  ' CSK%0')  (' MAPK8IP3%0'  ' CHUK%0')  (' MAPK8IP3%0'  ' RAC_f%0')  (' MAPK8IP3%0'  ' DUSP1%0')  (' MAPK8IP3%0'  ' TGFBR2%0')  (' MAPK8IP3%0'  ' ILR_f%0')  (' MAPK8IP3%0'  ' SYK%0')  (' MAPK8IP3%0'  ' IRAK1%0')  (' MAPK8IP3%0'  ' SHC1%0')  (' MAPK8IP3%0'  ' JAK_f%0')  (' MAPK8IP3%0'  ' CBPp300_c%0')  (' MAPK8IP3%0'  ' SKP2%0')  (' MAPK8IP3%0'  ' TP53%0')  (' MAPK8IP3%0'  ' SMAD7%0')  (' MAPK8IP3%0'  ' SMAD6%0')  (' MAPK8IP3%0'  ' DKK_f%0')  (' MAPK8IP3%0'  ' FOXO_f%0')  (' MAPK8IP3%0'  ' TCF7_f%0')  (' MAPK8IP3%0'  ' DKK_g%0')  (' MAPK8IP3%0'  ' MYC%0')  (' MAPK8IP3%0'  ' CCND1%0')  (' MAPK8IP3%0'  ' EGR1%0')  (' MAPK8IP3%0'  ' MMP_f%0')  (' MAPK8IP3%0'  ' PTEN_g%0')  (' MAPK8IP3%0'  ' RTPK_f%0')  (' MAPK8IP3%0'  ' CTNNB1%0')  (' MAPK8IP3%0'  'LEF1%0')  (' MAPK8IP3%0'  'SFRP1%0')  (' MAPK8IP3%0'  'FZD_f%0')  (' MAPK8IP3%0'  ' CASP8%0')  (' MAPK8IP3%0'  ' REL_f%0')  (' MAPK8IP3%0'  ' NFKB_f%0')  (' MAPK8IP3%0'  ' DVL_f%0')  (' MAPK8IP3%0'  ' LRP_f%0')  (' MAPK8IP3%0'  ' BTRC%0')  (' MAPK8IP3%0'  ' CK1_f%0')  (' MAPK8IP3%0'  ' AXIN1%0')  (' MAPK8IP3%0'  ' mTORC2_c%0')  (' MAPK8IP3%0'  ' PDPK1%0')  (' MAPK8IP3%0'  ' MEK_f%0')  (' MAPK8IP3%0'  ' CYCS%0')  (' MAPK8IP3%0'  ' CASP9%0')  (' MAPK8IP3%0'  ' GSK3_f%0')  (' MAPK8IP3%0'  ' IRS1%0')  (' MAPK8IP3%0'  ' MDM2%0')  (' MAPK8IP3%0'  ' AKT_f%0')  (' MAPK8IP3%0'  ' BCL2%0')  (' MAPK8IP3%0'  ' RAF_f%0')  (' MAPK8IP3%0'  ' mTORC1_c%0')  (' MAPK8IP3%0'  ' RHEB%0')  (' MAPK8IP3%0'  ' RTPK_g%0')  (' MAPK8IP3%0'  ' PTEN%0')  (' MAPK8IP3%0'  ' CASP3%0')  (' MAPK8IP3%0'  ' PIK3CA%0')  (' MAPK8IP3%0'  ' CREBBP%0')  (' MAPK8IP3%0'  ' PTPN11%0')  (' MAPK8IP3%0'  ' KRAS%0')  (' MAPK8IP3%0'  ' MAP2K4%0')  (' MAPK8IP3%0'  ' MAP2K7%0')  (' MAPK8IP3%0'  ' MAPK14%0')  (' MAPK8IP3%0'  ' JNK_f%0')  (' MAPK8IP3%0'  ' MAP2K3%0')  (' MAPK8IP3%0'  ' ERK_f%0')  (' MAPK8IP3%0'  ' LIF%0')  (' MAPK8IP3%0'  ' PPP1CA%0')  (' MAPK8IP3%0'  ' GAB_f%0')  (' MAPK8IP3%0'  ' SOS1%0')  (' MAPK8IP3%0'  ' PRKCA%0')  (' MAPK8IP3%0'  ' VAV1%0')  (' MAPK8IP3%0'  ' PLCG1%0')  (' MAPK8IP3%0'  ' PRKCD%0')  (' MAPK8IP3%0'  ' RSK_f%0')  (' MAPK8IP3%0'  ' S6K_f%0')  (' MAPK8IP3%0'  ' PLK1%0')  (' MAPK8IP3%0'  ' ILK%0')  (' MAPK8IP3%0'  ' SOCS1%0')  (' MAPK8IP3%0'  ' DUSP6%0')  (' MAPK8IP3%0'  ' STAT3%0')  (' MAPK8IP3%0'  ' LIMK2%0')  (' MAPK8IP3%0'  ' EP300%0')  (' MAPK8IP3%0'  ' STAT1%0')  (' MAPK8IP3%0'  ' IKBKB%0')  (' MAPK8IP3%0'  ' SRF%0')  (' MAPK8IP3%0'  ' PIAS1%0')  (' MAPK8IP3%0'  ' TRAF6%0')  (' MAPK8IP3%0'  ' SOCS1_g%0')  (' MAPK8IP3%0'  ' ISGF3_c%0')  (' MAPK8IP3%0'  ' STAT2%0')  (' MAPK8IP3%0'  ' CFLAR%0')  (' MAPK8IP3%0'  ' SMAD2%0')  (' MAPK8IP3%0'  ' MDM2_g%0')  (' MAPK8IP3%0'  ' BAX%0')  (' MAPK8IP3%0'  ' PRKACA%0')  (' MAPK8IP3%0'  ' TGFB1%0')  (' MAPK8IP3%0'  ' MAP3K8%0')  (' MAPK8IP3%0'  ' TSC_f%0')  (' MAPK8IP3%0'  ' SMAD4%0')  (' MAPK8IP3%0'  ' BAD%0')  (' MAPK8IP3%0'  ' MAP3K5%0')  (' MAPK8IP3%0'  ' AKT1S1%0')  (' MAPK8IP3%0'  ' SKI%0')  (' MAPK8IP3%0'  ' SMAD3%0')  (' MAPK8IP3%0'  ' MAPKAPK2%0')  (' MAPK8IP3%0'  ' DUSP1_g%0')  (' MAPK8IP3%0'  ' MSK_f%0')  (' MAPK8IP3%0'  ' GRAP2%0')  (' MAPK8IP3%0'  ' TAB_f%0')  (' MAPK8IP3%0'  ' ATF2%0')  (' MAPK8IP3%0'  ' SMAD5%0')  (' MAPK8IP3%0'  ' SMAD1%0')  (' MAPK8IP3%0'  ' FOS%0')  (' MAPK8IP3%0'  ' JUN%0')  (' MAPK8IP3%0'  ' MAP3K7%0')  (' MAPK8IP3%0'  ' NLK%0')  (' MAPK8IP3%0'  ' SMAD7_g%0')  (' MAPK8IP3%0'  ' SMAD6_g%0')  (' MAPK8IP3%0'  ' AP1_c%0')  (' MAPK8IP3%0'  ' ACVR1%0')  (' MAPK8IP3%0'  ' PTPN6%0')  (' MAPK8IP3%0'  ' CDC42%0')  (' MAPK8IP3%0'  ' GRB2%0')  (' MAPK8IP3%0'  ' TGFBR1%0')  (' MAPK8IP3%0'  ' SMURF1%0')  (' MAPK8IP3%0'  ' SMURF2%0')  (' MAPK8IP3%0'  ' RHOA%0')  (' MAPK8IP3%0'  ' BMPR2%0')  (' MAPK8IP3%0'  ' PARD6A%0')  (' MAPK8IP3%0'  ' DAAM1%0')  (' MAPK8IP3%0'  ' SFRP1_g%0')  (' MAPK8IP3%0'  ' PPM1A%0')  (' MAPK8IP3%0'  ' CFL_f%0')  (' MAPK8IP3%0'  ' PAK1%0')  (' MAPK8IP3%0'  ' MAP3K11%0')  (' MAPK8IP3%0'  ' MAP3K4%0')  (' MAPK8IP3%0'  ' LIMK1%0')  (' MAPK8IP3%0'  ' ROCK1%0')  (' MAPK8IP3%0'  ' ITCH%0')  (' MAPK8IP3%0'  ' ARHGAP24%0')  (' MAPK8IP3%0'  ' TIAM1%0')  (' MAPK8IP3%0'  ' RND3%0')  (' MAPK8IP3%0'  ' MXD1%0')  (' MAPK8IP3%0'  ' PIP3%0')  (' MXD1%0'  ' SRC%0')  (' MXD1%0'  ' CSK%0')  (' MXD1%0'  ' CHUK%0')  (' MXD1%0'  ' RAC_f%0')  (' MXD1%0'  ' DUSP1%0')  (' MXD1%0'  ' TGFBR2%0')  (' MXD1%0'  ' ILR_f%0')  (' MXD1%0'  ' SYK%0')  (' MXD1%0'  ' IRAK1%0')  (' MXD1%0'  ' SHC1%0')  (' MXD1%0'  ' JAK_f%0')  (' MXD1%0'  ' CBPp300_c%0')  (' MXD1%0'  ' SKP2%0')  (' MXD1%0'  ' TP53%0')  (' MXD1%0'  ' SMAD7%0')  (' MXD1%0'  ' SMAD6%0')  (' MXD1%0'  ' DKK_f%0')  (' MXD1%0'  ' FOXO_f%0')  (' MXD1%0'  ' TCF7_f%0')  (' MXD1%0'  ' DKK_g%0')  (' MXD1%0'  ' MYC%0')  (' MXD1%0'  ' CCND1%0')  (' MXD1%0'  ' EGR1%0')  (' MXD1%0'  ' MMP_f%0')  (' MXD1%0'  ' PTEN_g%0')  (' MXD1%0'  ' RTPK_f%0')  (' MXD1%0'  ' CTNNB1%0')  (' MXD1%0'  'LEF1%0')  (' MXD1%0'  'SFRP1%0')  (' MXD1%0'  'FZD_f%0')  (' MXD1%0'  ' CASP8%0')  (' MXD1%0'  ' REL_f%0')  (' MXD1%0'  ' NFKB_f%0')  (' MXD1%0'  ' DVL_f%0')  (' MXD1%0'  ' LRP_f%0')  (' MXD1%0'  ' BTRC%0')  (' MXD1%0'  ' CK1_f%0')  (' MXD1%0'  ' AXIN1%0')  (' MXD1%0'  ' mTORC2_c%0')  (' MXD1%0'  ' PDPK1%0')  (' MXD1%0'  ' MEK_f%0')  (' MXD1%0'  ' CYCS%0')  (' MXD1%0'  ' CASP9%0')  (' MXD1%0'  ' GSK3_f%0')  (' MXD1%0'  ' IRS1%0')  (' MXD1%0'  ' MDM2%0')  (' MXD1%0'  ' AKT_f%0')  (' MXD1%0'  ' BCL2%0')  (' MXD1%0'  ' RAF_f%0')  (' MXD1%0'  ' mTORC1_c%0')  (' MXD1%0'  ' RHEB%0')  (' MXD1%0'  ' RTPK_g%0')  (' MXD1%0'  ' PTEN%0')  (' MXD1%0'  ' CASP3%0')  (' MXD1%0'  ' PIK3CA%0')  (' MXD1%0'  ' CREBBP%0')  (' MXD1%0'  ' PTPN11%0')  (' MXD1%0'  ' KRAS%0')  (' MXD1%0'  ' MAP2K4%0')  (' MXD1%0'  ' MAP2K7%0')  (' MXD1%0'  ' MAPK14%0')  (' MXD1%0'  ' JNK_f%0')  (' MXD1%0'  ' MAP2K3%0')  (' MXD1%0'  ' ERK_f%0')  (' MXD1%0'  ' LIF%0')  (' MXD1%0'  ' PPP1CA%0')  (' MXD1%0'  ' GAB_f%0')  (' MXD1%0'  ' SOS1%0')  (' MXD1%0'  ' PRKCA%0')  (' MXD1%0'  ' VAV1%0')  (' MXD1%0'  ' PLCG1%0')  (' MXD1%0'  ' PRKCD%0')  (' MXD1%0'  ' RSK_f%0')  (' MXD1%0'  ' S6K_f%0')  (' MXD1%0'  ' PLK1%0')  (' MXD1%0'  ' ILK%0')  (' MXD1%0'  ' SOCS1%0')  (' MXD1%0'  ' DUSP6%0')  (' MXD1%0'  ' STAT3%0')  (' MXD1%0'  ' LIMK2%0')  (' MXD1%0'  ' EP300%0')  (' MXD1%0'  ' STAT1%0')  (' MXD1%0'  ' IKBKB%0')  (' MXD1%0'  ' SRF%0')  (' MXD1%0'  ' PIAS1%0')  (' MXD1%0'  ' TRAF6%0')  (' MXD1%0'  ' SOCS1_g%0')  (' MXD1%0'  ' ISGF3_c%0')  (' MXD1%0'  ' STAT2%0')  (' MXD1%0'  ' CFLAR%0')  (' MXD1%0'  ' SMAD2%0')  (' MXD1%0'  ' MDM2_g%0')  (' MXD1%0'  ' BAX%0')  (' MXD1%0'  ' PRKACA%0')  (' MXD1%0'  ' TGFB1%0')  (' MXD1%0'  ' MAP3K8%0')  (' MXD1%0'  ' TSC_f%0')  (' MXD1%0'  ' SMAD4%0')  (' MXD1%0'  ' BAD%0')  (' MXD1%0'  ' MAP3K5%0')  (' MXD1%0'  ' AKT1S1%0')  (' MXD1%0'  ' SKI%0')  (' MXD1%0'  ' SMAD3%0')  (' MXD1%0'  ' MAPKAPK2%0')  (' MXD1%0'  ' DUSP1_g%0')  (' MXD1%0'  ' MSK_f%0')  (' MXD1%0'  ' GRAP2%0')  (' MXD1%0'  ' TAB_f%0')  (' MXD1%0'  ' ATF2%0')  (' MXD1%0'  ' SMAD5%0')  (' MXD1%0'  ' SMAD1%0')  (' MXD1%0'  ' FOS%0')  (' MXD1%0'  ' JUN%0')  (' MXD1%0'  ' MAP3K7%0')  (' MXD1%0'  ' NLK%0')  (' MXD1%0'  ' SMAD7_g%0')  (' MXD1%0'  ' SMAD6_g%0')  (' MXD1%0'  ' AP1_c%0')  (' MXD1%0'  ' ACVR1%0')  (' MXD1%0'  ' PTPN6%0')  (' MXD1%0'  ' CDC42%0')  (' MXD1%0'  ' GRB2%0')  (' MXD1%0'  ' TGFBR1%0')  (' MXD1%0'  ' SMURF1%0')  (' MXD1%0'  ' SMURF2%0')  (' MXD1%0'  ' RHOA%0')  (' MXD1%0'  ' BMPR2%0')  (' MXD1%0'  ' PARD6A%0')  (' MXD1%0'  ' DAAM1%0')  (' MXD1%0'  ' SFRP1_g%0')  (' MXD1%0'  ' PPM1A%0')  (' MXD1%0'  ' CFL_f%0')  (' MXD1%0'  ' PAK1%0')  (' MXD1%0'  ' MAP3K11%0')  (' MXD1%0'  ' MAP3K4%0')  (' MXD1%0'  ' LIMK1%0')  (' MXD1%0'  ' ROCK1%0')  (' MXD1%0'  ' ITCH%0')  (' MXD1%0'  ' ARHGAP24%0')  (' MXD1%0'  ' TIAM1%0')  (' MXD1%0'  ' RND3%0')  (' MXD1%0'  ' MAPK8IP3%0')  (' MXD1%0'  ' PIP3%0')  (' PIP3%0'  ' SRC%0')  (' PIP3%0'  ' CSK%0')  (' PIP3%0'  ' CHUK%0')  (' PIP3%0'  ' RAC_f%0')  (' PIP3%0'  ' DUSP1%0')  (' PIP3%0'  ' TGFBR2%0')  (' PIP3%0'  ' ILR_f%0')  (' PIP3%0'  ' SYK%0')  (' PIP3%0'  ' IRAK1%0')  (' PIP3%0'  ' SHC1%0')  (' PIP3%0'  ' JAK_f%0')  (' PIP3%0'  ' CBPp300_c%0')  (' PIP3%0'  ' SKP2%0')  (' PIP3%0'  ' TP53%0')  (' PIP3%0'  ' SMAD7%0')  (' PIP3%0'  ' SMAD6%0')  (' PIP3%0'  ' DKK_f%0')  (' PIP3%0'  ' FOXO_f%0')  (' PIP3%0'  ' TCF7_f%0')  (' PIP3%0'  ' DKK_g%0')  (' PIP3%0'  ' MYC%0')  (' PIP3%0'  ' CCND1%0')  (' PIP3%0'  ' EGR1%0')  (' PIP3%0'  ' MMP_f%0')  (' PIP3%0'  ' PTEN_g%0')  (' PIP3%0'  ' RTPK_f%0')  (' PIP3%0'  ' CTNNB1%0')  (' PIP3%0'  'LEF1%0')  (' PIP3%0'  'SFRP1%0')  (' PIP3%0'  'FZD_f%0')  (' PIP3%0'  ' CASP8%0')  (' PIP3%0'  ' REL_f%0')  (' PIP3%0'  ' NFKB_f%0')  (' PIP3%0'  ' DVL_f%0')  (' PIP3%0'  ' LRP_f%0')  (' PIP3%0'  ' BTRC%0')  (' PIP3%0'  ' CK1_f%0')  (' PIP3%0'  ' AXIN1%0')  (' PIP3%0'  ' mTORC2_c%0')  (' PIP3%0'  ' PDPK1%0')  (' PIP3%0'  ' MEK_f%0')  (' PIP3%0'  ' CYCS%0')  (' PIP3%0'  ' CASP9%0')  (' PIP3%0'  ' GSK3_f%0')  (' PIP3%0'  ' IRS1%0')  (' PIP3%0'  ' MDM2%0')  (' PIP3%0'  ' AKT_f%0')  (' PIP3%0'  ' BCL2%0')  (' PIP3%0'  ' RAF_f%0')  (' PIP3%0'  ' mTORC1_c%0')  (' PIP3%0'  ' RHEB%0')  (' PIP3%0'  ' RTPK_g%0')  (' PIP3%0'  ' PTEN%0')  (' PIP3%0'  ' CASP3%0')  (' PIP3%0'  ' PIK3CA%0')  (' PIP3%0'  ' CREBBP%0')  (' PIP3%0'  ' PTPN11%0')  (' PIP3%0'  ' KRAS%0')  (' PIP3%0'  ' MAP2K4%0')  (' PIP3%0'  ' MAP2K7%0')  (' PIP3%0'  ' MAPK14%0')  (' PIP3%0'  ' JNK_f%0')  (' PIP3%0'  ' MAP2K3%0')  (' PIP3%0'  ' ERK_f%0')  (' PIP3%0'  ' LIF%0')  (' PIP3%0'  ' PPP1CA%0')  (' PIP3%0'  ' GAB_f%0')  (' PIP3%0'  ' SOS1%0')  (' PIP3%0'  ' PRKCA%0')  (' PIP3%0'  ' VAV1%0')  (' PIP3%0'  ' PLCG1%0')  (' PIP3%0'  ' PRKCD%0')  (' PIP3%0'  ' RSK_f%0')  (' PIP3%0'  ' S6K_f%0')  (' PIP3%0'  ' PLK1%0')  (' PIP3%0'  ' ILK%0')  (' PIP3%0'  ' SOCS1%0')  (' PIP3%0'  ' DUSP6%0')  (' PIP3%0'  ' STAT3%0')  (' PIP3%0'  ' LIMK2%0')  (' PIP3%0'  ' EP300%0')  (' PIP3%0'  ' STAT1%0')  (' PIP3%0'  ' IKBKB%0')  (' PIP3%0'  ' SRF%0')  (' PIP3%0'  ' PIAS1%0')  (' PIP3%0'  ' TRAF6%0')  (' PIP3%0'  ' SOCS1_g%0')  (' PIP3%0'  ' ISGF3_c%0')  (' PIP3%0'  ' STAT2%0')  (' PIP3%0'  ' CFLAR%0')  (' PIP3%0'  ' SMAD2%0')  (' PIP3%0'  ' MDM2_g%0')  (' PIP3%0'  ' BAX%0')  (' PIP3%0'  ' PRKACA%0')  (' PIP3%0'  ' TGFB1%0')  (' PIP3%0'  ' MAP3K8%0')  (' PIP3%0'  ' TSC_f%0')  (' PIP3%0'  ' SMAD4%0')  (' PIP3%0'  ' BAD%0')  (' PIP3%0'  ' MAP3K5%0')  (' PIP3%0'  ' AKT1S1%0')  (' PIP3%0'  ' SKI%0')  (' PIP3%0'  ' SMAD3%0')  (' PIP3%0'  ' MAPKAPK2%0')  (' PIP3%0'  ' DUSP1_g%0')  (' PIP3%0'  ' MSK_f%0')  (' PIP3%0'  ' GRAP2%0')  (' PIP3%0'  ' TAB_f%0')  (' PIP3%0'  ' ATF2%0')  (' PIP3%0'  ' SMAD5%0')  (' PIP3%0'  ' SMAD1%0')  (' PIP3%0'  ' FOS%0')  (' PIP3%0'  ' JUN%0')  (' PIP3%0'  ' MAP3K7%0')  (' PIP3%0'  ' NLK%0')  (' PIP3%0'  ' SMAD7_g%0')  (' PIP3%0'  ' SMAD6_g%0')  (' PIP3%0'  ' AP1_c%0')  (' PIP3%0'  ' ACVR1%0')  (' PIP3%0'  ' PTPN6%0')  (' PIP3%0'  ' CDC42%0')  (' PIP3%0'  ' GRB2%0')  (' PIP3%0'  ' TGFBR1%0')  (' PIP3%0'  ' SMURF1%0')  (' PIP3%0'  ' SMURF2%0')  (' PIP3%0'  ' RHOA%0')  (' PIP3%0'  ' BMPR2%0')  (' PIP3%0'  ' PARD6A%0')  (' PIP3%0'  ' DAAM1%0')  (' PIP3%0'  ' SFRP1_g%0')  (' PIP3%0'  ' PPM1A%0')  (' PIP3%0'  ' CFL_f%0')  (' PIP3%0'  ' PAK1%0')  (' PIP3%0'  ' MAP3K11%0')  (' PIP3%0'  ' MAP3K4%0')  (' PIP3%0'  ' LIMK1%0')  (' PIP3%0'  ' ROCK1%0')  (' PIP3%0'  ' ITCH%0')  (' PIP3%0'  ' ARHGAP24%0')  (' PIP3%0'  ' TIAM1%0')  (' PIP3%0'  ' RND3%0')  (' PIP3%0'  ' MAPK8IP3%0')  (' PIP3%0'  ' MXD1%0')]"

'''Define dictionaries to store attractors for each perturbation'''
fixpointlist = {}

'''trapspacelist is used for perturbations where no stable state is found
    to find eventual cyclic attractors.'''
trapspacelist = {}

for p in perturbations:
    fixpoints = biolqm.fixpoints(biolqm.perturbation(generic_lqm, p))
    if(fixpoints):
        fixpointlist[p] = fixpoints
    else:
        '''No stable state found, so we look for cycles'''
        trapspace = biolqm.trapspace(biolqm.perturbation(generic_lqm, p))
        trapspacelist[p] = trapspace

#see attractors in tabulated tables for each perturbation
for k, v in fixpointlist.items():
    print(k)
    sys.displayhook(tabulate(v))
    print()
    
for k, v in trapspacelist.items():
    print(k)
    sys.displayhook(tabulate(v))
    print()

 SRC%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 CSK%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	0	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 CHUK%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 RAC_f%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 DUSP1%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	1	0	1	0	1	1	1	1	0	1	0	0	0	0	0	1	2	1	1	0	1	0	1	0	0	1	1	1	0	1	1	1	0	0	0	1	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	1	0	1	0	1	1	1	1	0	0	0	0	1	1	1	1	1	0	0	1	0	0	0	1	0	0	0	0	1	1	1	0	0	1	0	0	1	0	1	1	0	0	0	1	1	1	1	0	1	1	1	0	0	1	0	0	1	1	0	0	0	0	1	1	0	0	0	1	0	0	0	1	1	0	1	1	1	0	0	0	1	1	1	1	0	1	1	1	0

 TGFBR2%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 ILR_f%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 SYK%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 IRAK1%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 SHC1%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 JAK_f%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 CBPp300_c%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 SKP2%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 TP53%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 SMAD7%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 SMAD6%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 DKK_f%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 FOXO_f%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	1	0	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 TCF7_f%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 DKK_g%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 MYC%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 CCND1%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	0	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	0	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 EGR1%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	0	1	0	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 MMP_f%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	0	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 PTEN_g%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	0	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 RTPK_f%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 CTNNB1%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

LEF1%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

SFRP1%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	0	1	1	1	1	1	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	1	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

FZD_f%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 CASP8%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	1	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	0	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	0	1	1	0	1	0	0	0	1	0	1	0	1	0	0	0	0	0	0	0	0	0	0	0	1	1	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	1	1	1	1	0	0	0	1	0	0	1	0

 REL_f%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	0	0	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	0	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 NFKB_f%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	0	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	0	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 DVL_f%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 LRP_f%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	0	0	1	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 BTRC%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 CK1_f%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 AXIN1%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 mTORC2_c%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	0	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 PDPK1%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 MEK_f%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 CYCS%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 CASP9%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 GSK3_f%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 IRS1%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	0	0	0	0	0	0	0	1	0	0	0	0	1	3	1	1	1	0	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 MDM2%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	1	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	1	1	0	1	0	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	1	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 AKT_f%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 BCL2%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 RAF_f%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 mTORC1_c%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 RHEB%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	0	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 RTPK_g%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	0	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 PTEN%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	0	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	0	1	0	0	0	1	1	0	1	0	1	1	1	0

 CASP3%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	1	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	0	1	1	0	1	0	0	0	1	0	1	0	1	0	0	0	0	0	0	0	0	0	0	0	1	1	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	1	1	1	1	0	0	0	1	0	0	1	0

 PIK3CA%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	0	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	0	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 CREBBP%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 PTPN11%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 KRAS%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 MAP2K4%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 MAP2K7%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	0	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 JNK_f%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 ERK_f%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 LIF%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 PPP1CA%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 GAB_f%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 SOS1%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 PRKCA%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 VAV1%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 PLCG1%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 PRKCD%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	0	0	0	1	0	0	0	1	1	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 RSK_f%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 S6K_f%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 PLK1%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 ILK%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 SOCS1%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 DUSP6%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 STAT3%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	0	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	0	1	0	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	0	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 LIMK2%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 EP300%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 STAT1%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 IKBKB%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 SRF%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	0	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 PIAS1%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	0	0	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	1	0	1	0	0	1	0	1	0	0	1	0	0	0	0	0	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 TRAF6%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 SOCS1_g%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 ISGF3_c%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 STAT2%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 CFLAR%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 SMAD2%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 MDM2_g%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	0	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 BAX%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 PRKACA%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	0	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	0	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 TGFB1%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 MAP3K8%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 TSC_f%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 SMAD4%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 BAD%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	1	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	0	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 AKT1S1%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	1	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	1	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	0	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 SKI%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	1	1	1	1	0	0	1	1	1	0	0	0	1	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 SMAD3%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 DUSP1_g%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	0	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 MSK_f%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	0	0	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	0	0	1	0	0	0	0	1	1	1	1	0	1	1	0	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 GRAP2%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 TAB_f%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 ATF2%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 SMAD5%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 SMAD1%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 FOS%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	0	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 JUN%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 MAP3K7%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 NLK%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 SMAD7_g%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 SMAD6_g%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 AP1_c%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 ACVR1%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 PTPN6%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 CDC42%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 GRB2%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 TGFBR1%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 SMURF1%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 SMURF2%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	0	1	0	0	0	0	0	0	0	0	0	1	0	0	2	0	0	0	0	1	0	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	1	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	1	0	0	0	0	0	1	0	0	1	0	0	0	0	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	0	0	0	0	0	1	0	0	0	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0
1	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 RHOA%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 BMPR2%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 PARD6A%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 DAAM1%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 SFRP1_g%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	0	1	1	1	1	1	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	1	0	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 PPM1A%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	0	1	0	0	0	1	1	0	1	0	1	1	1	0

 CFL_f%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	0	0	0	0	1	1	0	1	0	1	1	1	0

 PAK1%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 MAP3K11%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 MAP3K4%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 LIMK1%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	0	0	0	0	0	1	0	1	0	1	1	1	0

 ROCK1%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	1	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	1	0	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	1	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	1	1	1	1	0	0	0	1	0	0	1	0

 ITCH%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 ARHGAP24%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	1	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	1	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	1	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	1	1	1	1	1	0	0	0	1	1	1	0

 TIAM1%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 RND3%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	0	1	1	0

 MAPK8IP3%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	0	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	0	1	0

 MXD1%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	2	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	1	1	1	1	1	0	0	0	0	1	1	1	1	1	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	1	0	1	1	0	0	0	1	1	0	1	0	1	1	0	0

 PIP3%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

 MAPK14%0

	SRC	CSK	CHUK	RAC_f	Prosurvival_b1	Prosurvival_b2	Prosurvival_b3	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f_b1	FOXO_f_b2	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival_b1	Antisurvival_b2	Antisurvival_b3	Antisurvival_b4	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	1	1	0	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	0	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	0	254	254	1	254	0	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254

 MAP2K3%0

	SRC	CSK	CHUK	RAC_f	Prosurvival_b1	Prosurvival_b2	Prosurvival_b3	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f_b1	FOXO_f_b2	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival_b1	Antisurvival_b2	Antisurvival_b3	Antisurvival_b4	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	0	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254

 MAP3K5%0

	SRC	CSK	CHUK	RAC_f	Prosurvival_b1	Prosurvival_b2	Prosurvival_b3	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f_b1	FOXO_f_b2	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival_b1	Antisurvival_b2	Antisurvival_b3	Antisurvival_b4	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	0	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254

 MAPKAPK2%0

	SRC	CSK	CHUK	RAC_f	Prosurvival_b1	Prosurvival_b2	Prosurvival_b3	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f_b1	FOXO_f_b2	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival_b1	Antisurvival_b2	Antisurvival_b3	Antisurvival_b4	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	0	0	1	0	0	0	0	0	0	0	0	254	0	0	0	1	1	0	0	0	1	1	1	1	0	0	0	1	0	1	0	0	0	1	0	0	0	1	0	0	254	254	0	1	254	0	0	0	0	1	1	1	1	0	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	0	0	1	0	1	0	0	1	0	1	0	0	1	0	0	0	0	254	254	1	0	0	0	0	1	1	1	1	0	0	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

CASCADE 2.0 Pint prediction for new synergised combinations

#Convert the GINsim model to a Pint model
cascade_pint = ginsim.to_pint(generic_model)

# Then we specified the goal.
from pypint import Goal


# Using (having) method to Define the new initial state to our model here for exampe MEK and PI3K
model_initial = cascade_pint.having({"MYC": 0, "CCND1": 0})

alt = Goal("Antisurvival=2", "Prosurvival=3") | Goal("Antisurvival=1", "Prosurvival=2") | Goal("Antisurvival=0", "Prosurvival=1")

# To see if the goal is reachable in the original model initial state or not 
model_initial.reachability(alt) 

True

# To make sure that our modified initial state reach the goal or not
model_initial.having(MYC=0 , CCND1=0).reachability(alt)

True

# Pint reachability analysis can be used to identify mutations that control goal reachability.

mutations = model_initial.oneshot_mutations_for_cut(alt,maxsize=3)
mutations

This computation is an under-approximation: returned mutations are all valid, but they may be non-minimal, and some solutions may be missed.

Limiting solutions to mutations of at most 3 automata. Use maxsize argument to change.

[{'CHUK': 0, 'MYC': 0, 'PPP1CA': 1},
 {'CHUK': 0, 'GSK3_f': 1, 'PPP1CA': 1},
 {'CHUK': 0, 'PPP1CA': 1, 'PLK1': 0},
 {'CHUK': 0, 'PPP1CA': 1, 'MXD1': 1},
 {'ILR_f': 0, 'GSK3_f': 1, 'PPP1CA': 1},
 {'SHC1': 0, 'CCND1': 0, 'GSK3_f': 1},
 {'SHC1': 0, 'GSK3_f': 1, 'PPP1CA': 1},
 {'FOXO_f': 0, 'GSK3_f': 1, 'PPP1CA': 1},
 {'FOXO_f': 0, 'GSK3_f': 1, 'STAT3': 0},
 {'TCF7_f': 0, 'MYC': 0, 'PPP1CA': 1},
 {'TCF7_f': 0, 'GSK3_f': 1, 'PPP1CA': 1},
 {'TCF7_f': 0, 'PPP1CA': 1, 'PLK1': 0},
 {'TCF7_f': 0, 'PPP1CA': 1, 'MXD1': 1},
 {'MYC': 0, 'CCND1': 0, 'RTPK_f': 0},
 {'MYC': 0, 'CCND1': 0, 'PDPK1': 0},
 {'MYC': 0, 'CCND1': 0, 'MEK_f': 0},
 {'MYC': 0, 'CCND1': 0, 'MEK_f': 1},
 {'MYC': 0, 'CCND1': 0, 'MAPK14': 1},
 {'MYC': 0, 'CCND1': 0, 'ERK_f': 0},
 {'MYC': 0, 'CCND1': 0, 'PPP1CA': 1},
 {'MYC': 0, 'CCND1': 0, 'RSK_f': 0},
 {'MYC': 0, 'CCND1': 0, 'DUSP6': 1},
 {'MYC': 0, 'CTNNB1': 0, 'PPP1CA': 1},
 {'MYC': 0, 'BTRC': 1, 'PPP1CA': 1},
 {'MYC': 0, 'PPP1CA': 1, 'NLK': 1},
 {'CCND1': 0, 'RTPK_f': 0, 'GSK3_f': 1},
 {'CCND1': 0, 'RTPK_f': 0, 'MXD1': 1},
 {'CCND1': 0, 'PDPK1': 0, 'GSK3_f': 1},
 {'CCND1': 0, 'PDPK1': 0, 'MXD1': 1},
 {'CCND1': 0, 'MEK_f': 0, 'GSK3_f': 1},
 {'CCND1': 0, 'MEK_f': 0, 'MXD1': 1},
 {'CCND1': 0, 'MEK_f': 1, 'GSK3_f': 1},
 {'CCND1': 0, 'MEK_f': 1, 'MXD1': 1},
 {'CCND1': 0, 'GSK3_f': 1, 'AKT_f': 1},
 {'CCND1': 0, 'GSK3_f': 1, 'RAF_f': 0},
 {'CCND1': 0, 'GSK3_f': 1, 'RHEB': 1},
 {'CCND1': 0, 'GSK3_f': 1, 'PTEN': 1},
 {'CCND1': 0, 'GSK3_f': 1, 'KRAS': 0},
 {'CCND1': 0, 'GSK3_f': 1, 'MAPK14': 1},
 {'CCND1': 0, 'GSK3_f': 1, 'ERK_f': 0},
 {'CCND1': 0, 'GSK3_f': 1, 'PPP1CA': 1},
 {'CCND1': 0, 'GSK3_f': 1, 'RSK_f': 0},
 {'CCND1': 0, 'GSK3_f': 1, 'DUSP6': 1},
 {'CCND1': 0, 'GSK3_f': 1, 'GRB2': 0},
 {'CCND1': 0, 'MAPK14': 1, 'MXD1': 1},
 {'CCND1': 0, 'ERK_f': 0, 'MXD1': 1},
 {'CCND1': 0, 'PPP1CA': 1, 'MXD1': 1},
 {'CCND1': 0, 'RSK_f': 0, 'MXD1': 1},
 {'CCND1': 0, 'DUSP6': 1, 'MXD1': 1},
 {'RTPK_f': 0, 'GSK3_f': 1, 'PPP1CA': 1},
 {'RTPK_f': 0, 'GSK3_f': 1, 'STAT3': 0},
 {'CTNNB1': 0, 'GSK3_f': 1, 'PPP1CA': 1},
 {'CTNNB1': 0, 'PPP1CA': 1, 'PLK1': 0},
 {'CTNNB1': 0, 'PPP1CA': 1, 'MXD1': 1},
 {'BTRC': 1, 'GSK3_f': 1, 'PPP1CA': 1},
 {'BTRC': 1, 'PPP1CA': 1, 'PLK1': 0},
 {'BTRC': 1, 'PPP1CA': 1, 'MXD1': 1},
 {'MEK_f': 1, 'GSK3_f': 1, 'PPP1CA': 1},
 {'MEK_f': 1, 'GSK3_f': 1, 'STAT3': 0},
 {'GSK3_f': 1, 'RAF_f': 0, 'PPP1CA': 1},
 {'GSK3_f': 1, 'RHEB': 1, 'PPP1CA': 1},
 {'GSK3_f': 1, 'RTPK_g': 0, 'PPP1CA': 1},
 {'GSK3_f': 1, 'RTPK_g': 0, 'STAT3': 0},
 {'GSK3_f': 1, 'PTEN': 1, 'PPP1CA': 1},
 {'GSK3_f': 1, 'PTEN': 1, 'STAT3': 0},
 {'GSK3_f': 1, 'KRAS': 0, 'PPP1CA': 1},
 {'GSK3_f': 1, 'MAPK14': 1, 'PPP1CA': 1},
 {'GSK3_f': 1, 'MAPK14': 1, 'STAT3': 0},
 {'GSK3_f': 1, 'LIF': 0, 'PPP1CA': 1},
 {'GSK3_f': 1, 'PPP1CA': 1, 'NLK': 1},
 {'GSK3_f': 1, 'PPP1CA': 1, 'GRB2': 0},
 {'PPP1CA': 1, 'PLK1': 0, 'NLK': 1},
 {'PPP1CA': 1, 'NLK': 1, 'MXD1': 1}]

# Single perturbation for the node CCND1 as we noticed that it has high freqence among the combinations.
mbs_CCND1 = biolqm.to_maboss(generic_lqm)
mbs_CCND1.mutate("CCND1","OFF")


output = ['Prosurvival_b1','Prosurvival_b2','Prosurvival_b3', 'Antisurvival_b1', 'Antisurvival_b2','Antisurvival_b3']

maboss.set_output(mbs_CCND1,output)

mbs_CCND1.update_parameters(sample_count=1000,time_tick=1.0, max_time=100)

CCND1_sim = mbs_CCND1.run()

CCND1_sim.plot_trajectory()

CCND1_sim.plot_piechart()

CCND1 showed maximum value of Antisurvival = -3 so we decided to exclue it from the predicted compinations.

Maboss stocastic simulation used to confirm pint predicted combinations for the nodes that were predicted as high influence in addition to having high synergy scores combinations predicted using CASCADE 2.0 model and the results gave 100% of the antisurvival output at its maximum value = 3 which gives good indication regards the combinations synergy.

# running prediction by changing the initial state to see if there any change in the predicted combinations

 #Using (having) method to Define the new initial state to our model here for exampe MEK and PI3K
model_ini = cascade_pint.having({"RTPK_f": 0,"RSK_f": 0})

alt = Goal("Antisurvival=2", "Prosurvival=3") | Goal("Antisurvival=1", "Prosurvival=2") | Goal("Antisurvival=0", "Prosurvival=1")

# To see if the goal is reachable in the original model initial state or not 
model_ini.reachability(alt) 

# To make sure that our modified initial state reach the goal or not
model_ini.having(RTPK_f=0 , RSK_f=0).reachability(alt)

# Pint reachability analysis can be used to identify mutations that control goal reachability.

mutations = model_ini.oneshot_mutations_for_cut(alt,maxsize=3)
mutations

This computation is an under-approximation: returned mutations are all valid, but they may be non-minimal, and some solutions may be missed.

Limiting solutions to mutations of at most 3 automata. Use maxsize argument to change.

[{'CHUK': 0, 'MYC': 0, 'PPP1CA': 1},
 {'CHUK': 0, 'GSK3_f': 1, 'PPP1CA': 1},
 {'CHUK': 0, 'PPP1CA': 1, 'PLK1': 0},
 {'CHUK': 0, 'PPP1CA': 1, 'MXD1': 1},
 {'ILR_f': 0, 'GSK3_f': 1, 'PPP1CA': 1},
 {'SHC1': 0, 'CCND1': 0, 'GSK3_f': 1},
 {'SHC1': 0, 'GSK3_f': 1, 'PPP1CA': 1},
 {'FOXO_f': 0, 'GSK3_f': 1, 'PPP1CA': 1},
 {'FOXO_f': 0, 'GSK3_f': 1, 'STAT3': 0},
 {'TCF7_f': 0, 'MYC': 0, 'PPP1CA': 1},
 {'TCF7_f': 0, 'GSK3_f': 1, 'PPP1CA': 1},
 {'TCF7_f': 0, 'PPP1CA': 1, 'PLK1': 0},
 {'TCF7_f': 0, 'PPP1CA': 1, 'MXD1': 1},
 {'MYC': 0, 'CCND1': 0, 'RTPK_f': 0},
 {'MYC': 0, 'CCND1': 0, 'PDPK1': 0},
 {'MYC': 0, 'CCND1': 0, 'MEK_f': 0},
 {'MYC': 0, 'CCND1': 0, 'MEK_f': 1},
 {'MYC': 0, 'CCND1': 0, 'MAPK14': 1},
 {'MYC': 0, 'CCND1': 0, 'ERK_f': 0},
 {'MYC': 0, 'CCND1': 0, 'PPP1CA': 1},
 {'MYC': 0, 'CCND1': 0, 'RSK_f': 0},
 {'MYC': 0, 'CCND1': 0, 'DUSP6': 1},
 {'MYC': 0, 'CTNNB1': 0, 'PPP1CA': 1},
 {'MYC': 0, 'BTRC': 1, 'PPP1CA': 1},
 {'MYC': 0, 'PPP1CA': 1, 'NLK': 1},
 {'CCND1': 0, 'RTPK_f': 0, 'GSK3_f': 1},
 {'CCND1': 0, 'RTPK_f': 0, 'MXD1': 1},
 {'CCND1': 0, 'PDPK1': 0, 'GSK3_f': 1},
 {'CCND1': 0, 'PDPK1': 0, 'MXD1': 1},
 {'CCND1': 0, 'MEK_f': 0, 'GSK3_f': 1},
 {'CCND1': 0, 'MEK_f': 0, 'MXD1': 1},
 {'CCND1': 0, 'MEK_f': 1, 'GSK3_f': 1},
 {'CCND1': 0, 'MEK_f': 1, 'MXD1': 1},
 {'CCND1': 0, 'GSK3_f': 1, 'AKT_f': 1},
 {'CCND1': 0, 'GSK3_f': 1, 'RAF_f': 0},
 {'CCND1': 0, 'GSK3_f': 1, 'RHEB': 1},
 {'CCND1': 0, 'GSK3_f': 1, 'PTEN': 1},
 {'CCND1': 0, 'GSK3_f': 1, 'KRAS': 0},
 {'CCND1': 0, 'GSK3_f': 1, 'MAPK14': 1},
 {'CCND1': 0, 'GSK3_f': 1, 'ERK_f': 0},
 {'CCND1': 0, 'GSK3_f': 1, 'PPP1CA': 1},
 {'CCND1': 0, 'GSK3_f': 1, 'RSK_f': 0},
 {'CCND1': 0, 'GSK3_f': 1, 'DUSP6': 1},
 {'CCND1': 0, 'GSK3_f': 1, 'GRB2': 0},
 {'CCND1': 0, 'MAPK14': 1, 'MXD1': 1},
 {'CCND1': 0, 'ERK_f': 0, 'MXD1': 1},
 {'CCND1': 0, 'PPP1CA': 1, 'MXD1': 1},
 {'CCND1': 0, 'RSK_f': 0, 'MXD1': 1},
 {'CCND1': 0, 'DUSP6': 1, 'MXD1': 1},
 {'RTPK_f': 0, 'GSK3_f': 1, 'PPP1CA': 1},
 {'RTPK_f': 0, 'GSK3_f': 1, 'STAT3': 0},
 {'CTNNB1': 0, 'GSK3_f': 1, 'PPP1CA': 1},
 {'CTNNB1': 0, 'PPP1CA': 1, 'PLK1': 0},
 {'CTNNB1': 0, 'PPP1CA': 1, 'MXD1': 1},
 {'BTRC': 1, 'GSK3_f': 1, 'PPP1CA': 1},
 {'BTRC': 1, 'PPP1CA': 1, 'PLK1': 0},
 {'BTRC': 1, 'PPP1CA': 1, 'MXD1': 1},
 {'MEK_f': 1, 'GSK3_f': 1, 'PPP1CA': 1},
 {'MEK_f': 1, 'GSK3_f': 1, 'STAT3': 0},
 {'GSK3_f': 1, 'RAF_f': 0, 'PPP1CA': 1},
 {'GSK3_f': 1, 'RHEB': 1, 'PPP1CA': 1},
 {'GSK3_f': 1, 'RTPK_g': 0, 'PPP1CA': 1},
 {'GSK3_f': 1, 'RTPK_g': 0, 'STAT3': 0},
 {'GSK3_f': 1, 'PTEN': 1, 'PPP1CA': 1},
 {'GSK3_f': 1, 'PTEN': 1, 'STAT3': 0},
 {'GSK3_f': 1, 'KRAS': 0, 'PPP1CA': 1},
 {'GSK3_f': 1, 'MAPK14': 1, 'PPP1CA': 1},
 {'GSK3_f': 1, 'MAPK14': 1, 'STAT3': 0},
 {'GSK3_f': 1, 'LIF': 0, 'PPP1CA': 1},
 {'GSK3_f': 1, 'PPP1CA': 1, 'NLK': 1},
 {'GSK3_f': 1, 'PPP1CA': 1, 'GRB2': 0},
 {'PPP1CA': 1, 'PLK1': 0, 'NLK': 1},
 {'PPP1CA': 1, 'NLK': 1, 'MXD1': 1}]

By changing the initial state, the same predicted combinations were noticed.

Single perturbation for nodes in pint predicted combinations

generic_perturbations = ["CCND1%0" , "STAT3%0" , "CHUK%0", "MYC%0", "RTPK_f%0" ,"RTPK_g%0", "MYC%0", "RSK_f%0" , "TCF7_f%0", "PLK1%0", "GRB2%0" , "ERK_f%0"]

'''Define dictionaries to store attractors for each perturbation'''
fixpointlist = {}

'''trapspacelist is used for perturbations where no stable state is found
    to find eventual cyclic attractors.'''
trapspacelist = {}

for p in generic_perturbations:
    fixpoints = biolqm.fixpoints(biolqm.perturbation(generic_lqm, p))
    if(fixpoints):
        fixpointlist[p] = fixpoints
    else:
        '''No stable state found, so we look for cycles'''
        trapspace = biolqm.trapspace(biolqm.perturbation(generic_lqm, p))
        trapspacelist[p] = trapspace

#see attractors in tabulated tables for each perturbation
for k, v in fixpointlist.items():
    print(k)
    sys.displayhook(tabulate(v))
    print()
    
for k, v in trapspacelist.items():
    print(k)
    sys.displayhook(tabulate(v))
    print()

CCND1%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	0	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	0	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

STAT3%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	0	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	0	1	0	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	0	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

CHUK%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

MYC%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

RTPK_f%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

RTPK_g%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	0	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

RSK_f%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

TCF7_f%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

PLK1%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

GRB2%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

ERK_f%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

growth CCND1 = -3 RTPK_f = -2 RTPK_g = -2 RSK_f = -2 GRB2 = -2 ERK_f = -2 STAT3 = -3 CHUK = -2 MYC= -2 TCF7_f = -2 PLK1 = -2

Double perturbation for the predicted combinations from pint

Double_perturbation = ["MYC%0 RTPK_f%0", "MYC%0 ERK_f%0", "MYC%0 RSK_f%0", "TCF7_f%0 MYC%0", "TCF7_f%0 PLK1%0", "CHUK%0 MYC%0", "CHUK%0 PLK1%0", "RTPK_g%0 STAT3%0"]

'''Define dictionaries to store attractors for each perturbation'''
fixpointlist = {}

'''trapspacelist is used for perturbations where no stable state is found
    to find eventual cyclic attractors.'''
trapspacelist = {}

for p in Double_perturbation:
    fixpoints = biolqm.fixpoints(biolqm.perturbation(generic_lqm, p))
    if(fixpoints):
        fixpointlist[p] = fixpoints
    else:
        '''No stable state found, so we look for cycles'''
        trapspace = biolqm.trapspace(biolqm.perturbation(generic_lqm, p))
        trapspacelist[p] = trapspace

#see attractors in tabulated tables for each perturbation
for k, v in fixpointlist.items():
    print(k)
    sys.displayhook(tabulate(v))
    print()
    
for k, v in trapspacelist.items():
    print(k)
    sys.displayhook(tabulate(v))
    print()

MYC%0 RTPK_f%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

MYC%0 ERK_f%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

MYC%0 RSK_f%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

TCF7_f%0 MYC%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

TCF7_f%0 PLK1%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

CHUK%0 MYC%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

CHUK%0 PLK1%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	1	1	1	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	1	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

RTPK_g%0 STAT3%0

	SRC	CSK	CHUK	RAC_f	Prosurvival	DUSP1	TGFBR2	ILR_f	SYK	IRAK1	SHC1	JAK_f	CBPp300_c	SKP2	TP53	SMAD7	SMAD6	DKK_f	FOXO_f	TCF7_f	DKK_g	MYC	CCND1	EGR1	MMP_f	PTEN_g	RTPK_f	CTNNB1	LEF1	SFRP1	FZD_f	CASP8	REL_f	NFKB_f	DVL_f	LRP_f	BTRC	CK1_f	AXIN1	mTORC2_c	PDPK1	MEK_f	CYCS	CASP9	GSK3_f	IRS1	MDM2	AKT_f	BCL2	RAF_f	mTORC1_c	RHEB	Antisurvival	RTPK_g	PTEN	CASP3	PIK3CA	CREBBP	PTPN11	KRAS	MAP2K4	MAP2K7	MAPK14	JNK_f	MAP2K3	ERK_f	LIF	PPP1CA	GAB_f	SOS1	PRKCA	VAV1	PLCG1	PRKCD	RSK_f	S6K_f	PLK1	ILK	SOCS1	DUSP6	STAT3	LIMK2	EP300	STAT1	IKBKB	SRF	PIAS1	TRAF6	SOCS1_g	ISGF3_c	STAT2	CFLAR	SMAD2	MDM2_g	BAX	PRKACA	TGFB1	MAP3K8	TSC_f	SMAD4	BAD	MAP3K5	AKT1S1	SKI	SMAD3	MAPKAPK2	DUSP1_g	MSK_f	GRAP2	TAB_f	ATF2	SMAD5	SMAD1	FOS	JUN	MAP3K7	NLK	SMAD7_g	SMAD6_g	AP1_c	ACVR1	PTPN6	CDC42	GRB2	TGFBR1	SMURF1	SMURF2	RHOA	BMPR2	PARD6A	DAAM1	SFRP1_g	PPM1A	CFL_f	PAK1	MAP3K11	MAP3K4	LIMK1	ROCK1	ITCH	ARHGAP24	TIAM1	RND3	MAPK8IP3	MXD1	PIP3
0	0	1	0	0	0	1	0	0	0	0	0	0	0	0	0	0	0	0	2	0	0	0	0	1	0	1	0	0	0	1	0	1	1	1	0	1	0	0	0	1	0	0	0	0	0	1	1	0	0	0	0	1	3	0	1	1	1	0	0	0	0	1	1	0	1	0	0	0	0	0	0	0	0	1	0	0	1	0	0	0	0	0	0	0	0	1	1	0	0	0	0	0	0	1	0	1	0	0	0	0	1	1	1	1	0	1	1	1	0	0	0	0	0	1	0	0	0	0	0	0	1	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	0	1	1	0	1	0	1	1	1	0

Double perturbation showed that there is no synergy so we tried to use maboss simulation to run triple perturbation

MaBoSS simulation used to confirm the triple perturbation

mbs_MYC = biolqm.to_maboss(generic_lqm)
mbs_MYC.mutate("MYC","OFF")


output = ['Prosurvival_b1','Prosurvival_b2','Prosurvival_b3', 'Antisurvival_b1', 'Antisurvival_b2','Antisurvival_b3']

maboss.set_output(mbs_MYC,output)

mbs_MYC.update_parameters(sample_count=1000,time_tick=1.0, max_time=100)

MYC_sim = mbs_MYC.run()

MYC_sim.plot_trajectory()

MYC_sim.plot_piechart()

Growth = -2

mbs_CHUK = biolqm.to_maboss(generic_lqm)
mbs_CHUK.mutate("CHUK","OFF")


output = ['Prosurvival_b1','Prosurvival_b2','Prosurvival_b3', 'Antisurvival_b1', 'Antisurvival_b2','Antisurvival_b3']

maboss.set_output(mbs_CHUK,output)

mbs_CHUK.update_parameters(sample_count=1000,time_tick=1.0, max_time=100)

CHUK_sim = mbs_MYC.run()

CHUK_sim.plot_trajectory()

CHUK_sim.plot_piechart()

 Growth = -2

double  = biolqm.to_maboss(generic_lqm)
double.mutate("MYC","OFF")
double.mutate("CHUK","OFF")

output = ['Prosurvival_b1','Prosurvival_b2','Prosurvival_b3', 'Antisurvival_b1', 'Antisurvival_b2','Antisurvival_b3']

maboss.set_output(double,output)

double.update_parameters(sample_count=1000,time_tick=1.0, max_time=100)

double_sim = double.run()

double_sim.plot_trajectory()

double_sim.plot_piechart()

Growth = -2 which means that there is no synergy in double perturbation

Triple perturbation was done to see if there is any synergy or not

a = biolqm.to_maboss(generic_lqm)
a.mutate("MYC","OFF")
a.mutate("CHUK","OFF")
a.mutate("PPP1CA","ON")

output = ['Prosurvival_b1','Prosurvival_b2','Prosurvival_b3', 'Antisurvival_b1', 'Antisurvival_b2','Antisurvival_b3']

maboss.set_output(a,output)

a.update_parameters(sample_count=1000,time_tick=1.0, max_time=100)

a_sim = a.run()

a_sim.plot_trajectory()

a_sim.plot_piechart()

Growth = -3

Triple prediction showed strong synergy and more growth inhibition than single and double perturbation the same simulation used for all the predicted combinations and it gives the same results which means that there is a synergy in triple combinations.

a = biolqm.to_maboss(generic_lqm)
a.mutate("PLK1","OFF")
a.mutate("CHUK","OFF")
a.mutate("PPP1CA","ON")

output = ['Prosurvival_b1','Prosurvival_b2','Prosurvival_b3', 'Antisurvival_b1', 'Antisurvival_b2','Antisurvival_b3']

maboss.set_output(a,output)

a.update_parameters(sample_count=1000,time_tick=1.0, max_time=100)

a_sim = a.run()

a_sim.plot_trajectory()
a_sim.plot_piechart()

CASCADE 1.0

confirmation of predicted combinations from pint using maboss stochastic simulation.

ags = ginsim.load("/tmp/colomotogioncrpg_Flobak_FullModel_S2_Dataset.zginml")

ags_lqm= ginsim.to_biolqm(ags)

b = biolqm.to_maboss(ags_lqm)
b.mutate("TCF","OFF")
output = ['Prosurvival_b1','Prosurvival_b2','Prosurvival_b3', 'Antisurvival_b1', 'Antisurvival_b2','Antisurvival_b3']

maboss.set_output(b,output)

b.update_parameters(sample_count=1000,time_tick=1.0, max_time=100)

b_sim = b.run()

b_sim.plot_trajectory()
b_sim.plot_piechart()

b = biolqm.to_maboss(ags_lqm)
b.mutate("TCF","OFF")
b.mutate("ERK","OFF")

output = ['Prosurvival_b1','Prosurvival_b2','Prosurvival_b3', 'Antisurvival_b1', 'Antisurvival_b2','Antisurvival_b3']

maboss.set_output(b,output)

b.update_parameters(sample_count=1000,time_tick=1.0, max_time=100)

b_sim = b.run()

b_sim.plot_trajectory()
b_sim.plot_piechart()

b = biolqm.to_maboss(ags_lqm)
b.mutate("TCF","OFF")
b.mutate("RSK","OFF")

output = ['Prosurvival_b1','Prosurvival_b2','Prosurvival_b3', 'Antisurvival_b1', 'Antisurvival_b2','Antisurvival_b3']

maboss.set_output(b,output)

b.update_parameters(sample_count=1000,time_tick=1.0, max_time=100)

b_sim = b.run()

b_sim.plot_trajectory()
b_sim.plot_piechart()

c = biolqm.to_maboss(ags_lqm)
c.mutate("TCF","OFF")
c.mutate("PI3K","OFF")

output = ['Prosurvival_b1','Prosurvival_b2','Prosurvival_b3', 'Antisurvival_b1', 'Antisurvival_b2','Antisurvival_b3']

maboss.set_output(c,output)

c.update_parameters(sample_count=1000,time_tick=1.0, max_time=100)

c_sim = b.run()

c_sim.plot_trajectory()
c_sim.plot_piechart()

~ 53% predicted to have growth of -1

BioLQM perturbation used to see the growth inhibition value for single and double mutation for the pint predicted combinations (CASCADE 1.0)

ags = ginsim.load("/tmp/colomotoqwjmz4j__Flobak_FullModel_S2_Dataset.zginml")

ags_lqm = ginsim.to_biolqm(ags)

Double perturbation

ags_perturbation = ["cMYC%0 CCND1%0", "TCF%0 ERK%0", "PI3K%0 TCF%0", "TCF%0 PDK1%0", "TCF%0 RSK%0" , "TCF%0 CCND1%0"]

'''Define dictionaries to store attractors for each perturbation'''
fixpointlist = {}

'''trapspacelist is used for perturbations where no stable state is found
    to find eventual cyclic attractors.'''
trapspacelist = {}

for p in ags_perturbation:
    fixpoints = biolqm.fixpoints(biolqm.perturbation(ags_lqm, p))
    if(fixpoints):
        fixpointlist[p] = fixpoints
    else:
        '''No stable state found, so we look for cycles'''
        trapspace = biolqm.trapspace(biolqm.perturbation(ags_lqm, p))
        trapspacelist[p] = trapspace

#see attractors in tabulated tables for each perturbation
for k, v in fixpointlist.items():
    print(k)
    sys.displayhook(tabulate(v))
    print()
    
for k, v in trapspacelist.items():
    print(k)
    sys.displayhook(tabulate(v))
    print()

cMYC%0 CCND1%0

	RTPK	SHC1	GRB2	SOS	Ras	Raf	MEK	ERK	DUSP6	TAK1	MKK3	ASK1	TAB	p38alpha	DUSP1	MKK4	MKK7	MEKK4	MLK3	Rac	JNK	GRAP2	SHP2	GAB	IKKB	IKKA	AKT	IRS1	Caspase8	PTENgene	Caspase9	FOXO	TSC	pras40	BCL2	p53	Rheb	mTORC1	PTEN	BAD	mTORC2	MDM2gene	S6K	MDM2	CytochromeC	BAX	NFkB	MAP3K8	PI3K	PDK1	LRP	ITCH	DKK1	Fz	Antisurvival	Axin	GSK3	RTPKgene	RSK	MSK	CFLAR	CK1	Dvl	SFRP1	SFRP1gene	Caspase37	betacatenin	betaTrCP	MMP	Egr1	LEF	Prosurvival	cMYC	TCF	NLK	DKK1gene	CCND1
0	0	1	1	1	1	1	1	1	1	1	1	0	1	0	1	1	1	0	0	0	0	1	0	0	1	1	1	0	0	0	0	0	0	0	1	0	1	1	0	0	0	1	1	0	0	0	1	1	1	1	0	0	1	0	0	1	0	0	1	1	1	1	0	1	1	0	1	0	1	0	1	0	0	1	1	1	0

PI3K%0 TCF%0

	RTPK	SHC1	GRB2	SOS	Ras	Raf	MEK	ERK	DUSP6	TAK1	MKK3	ASK1	TAB	p38alpha	DUSP1	MKK4	MKK7	MEKK4	MLK3	Rac	JNK	GRAP2	SHP2	GAB	IKKB	IKKA	AKT	IRS1	Caspase8	PTENgene	Caspase9	FOXO	TSC	pras40	BCL2	p53	Rheb	mTORC1	PTEN	BAD	mTORC2	MDM2gene	S6K	MDM2	CytochromeC	BAX	NFkB	MAP3K8	PI3K	PDK1	LRP	ITCH	DKK1	Fz	Antisurvival	Axin	GSK3	RTPKgene	RSK	MSK	CFLAR	CK1	Dvl	SFRP1	SFRP1gene	Caspase37	betacatenin	betaTrCP	MMP	Egr1	LEF	Prosurvival	cMYC	TCF	NLK	DKK1gene	CCND1
0	0	0	0	0	0	0	1	1	1	1	1	1	1	0	1	1	1	0	0	0	0	1	0	0	1	0	0	0	1	1	0	0	0	1	0	0	1	0	1	1	0	1	0	1	0	0	1	1	0	0	1	0	0	0	1	0	0	0	0	1	0	0	0	1	1	1	1	0	1	1	1	0	0	0	1	0	0

TCF%0 PDK1%0

	RTPK	SHC1	GRB2	SOS	Ras	Raf	MEK	ERK	DUSP6	TAK1	MKK3	ASK1	TAB	p38alpha	DUSP1	MKK4	MKK7	MEKK4	MLK3	Rac	JNK	GRAP2	SHP2	GAB	IKKB	IKKA	AKT	IRS1	Caspase8	PTENgene	Caspase9	FOXO	TSC	pras40	BCL2	p53	Rheb	mTORC1	PTEN	BAD	mTORC2	MDM2gene	S6K	MDM2	CytochromeC	BAX	NFkB	MAP3K8	PI3K	PDK1	LRP	ITCH	DKK1	Fz	Antisurvival	Axin	GSK3	RTPKgene	RSK	MSK	CFLAR	CK1	Dvl	SFRP1	SFRP1gene	Caspase37	betacatenin	betaTrCP	MMP	Egr1	LEF	Prosurvival	cMYC	TCF	NLK	DKK1gene	CCND1
0	0	0	0	0	0	0	1	1	1	1	1	1	1	0	1	1	1	0	0	0	0	1	0	0	1	0	0	0	1	1	0	0	0	1	0	0	1	0	1	1	0	1	0	1	0	0	1	1	0	0	1	0	0	0	1	0	0	0	0	1	0	0	0	1	1	1	1	0	1	1	1	0	0	0	1	0	0

TCF%0 RSK%0

	RTPK	SHC1	GRB2	SOS	Ras	Raf	MEK	ERK	DUSP6	TAK1	MKK3	ASK1	TAB	p38alpha	DUSP1	MKK4	MKK7	MEKK4	MLK3	Rac	JNK	GRAP2	SHP2	GAB	IKKB	IKKA	AKT	IRS1	Caspase8	PTENgene	Caspase9	FOXO	TSC	pras40	BCL2	p53	Rheb	mTORC1	PTEN	BAD	mTORC2	MDM2gene	S6K	MDM2	CytochromeC	BAX	NFkB	MAP3K8	PI3K	PDK1	LRP	ITCH	DKK1	Fz	Antisurvival	Axin	GSK3	RTPKgene	RSK	MSK	CFLAR	CK1	Dvl	SFRP1	SFRP1gene	Caspase37	betacatenin	betaTrCP	MMP	Egr1	LEF	Prosurvival	cMYC	TCF	NLK	DKK1gene	CCND1
0	0	0	0	0	0	0	1	1	1	1	1	1	1	0	1	1	1	0	0	0	0	1	0	0	1	0	0	0	1	1	0	0	0	1	0	0	1	0	1	1	0	1	0	1	0	0	1	1	0	0	1	0	0	0	1	0	0	0	0	1	0	0	0	1	1	1	1	0	1	1	1	0	0	0	1	0	0

TCF%0 CCND1%0

	RTPK	SHC1	GRB2	SOS	Ras	Raf	MEK	ERK	DUSP6	TAK1	MKK3	ASK1	TAB	p38alpha	DUSP1	MKK4	MKK7	MEKK4	MLK3	Rac	JNK	GRAP2	SHP2	GAB	IKKB	IKKA	AKT	IRS1	Caspase8	PTENgene	Caspase9	FOXO	TSC	pras40	BCL2	p53	Rheb	mTORC1	PTEN	BAD	mTORC2	MDM2gene	S6K	MDM2	CytochromeC	BAX	NFkB	MAP3K8	PI3K	PDK1	LRP	ITCH	DKK1	Fz	Antisurvival	Axin	GSK3	RTPKgene	RSK	MSK	CFLAR	CK1	Dvl	SFRP1	SFRP1gene	Caspase37	betacatenin	betaTrCP	MMP	Egr1	LEF	Prosurvival	cMYC	TCF	NLK	DKK1gene	CCND1
0	0	0	0	0	0	0	1	1	1	1	1	1	1	0	1	1	1	0	0	0	0	1	0	0	1	0	0	0	1	1	0	0	0	1	0	0	1	0	1	1	0	1	0	1	0	0	1	1	0	0	1	0	0	0	1	0	0	0	0	1	0	0	0	1	1	1	1	0	1	1	1	0	0	0	1	0	0

TCF%0 ERK%0

	RTPK	SHC1	GRB2	SOS	Ras	Raf	MEK	ERK	DUSP6	TAK1	MKK3	ASK1	TAB	p38alpha	DUSP1	MKK4	MKK7	MEKK4	MLK3	Rac	JNK	GRAP2	SHP2	GAB	IKKB	IKKA	AKT	IRS1	Caspase8	PTENgene	Caspase9	FOXO	TSC	pras40	BCL2	p53	Rheb	mTORC1	PTEN	BAD	mTORC2	MDM2gene	S6K	MDM2	CytochromeC	BAX	NFkB	MAP3K8	PI3K	PDK1	LRP	ITCH	DKK1	Fz	Antisurvival_b1	Antisurvival_b2	Antisurvival_b3	Axin	GSK3	RTPKgene	RSK	MSK	CFLAR	CK1	Dvl	SFRP1	SFRP1gene	Caspase37_b1	Caspase37_b2	betacatenin	betaTrCP	MMP	Egr1	LEF	Prosurvival_b1	Prosurvival_b2	Prosurvival_b3	cMYC	TCF	NLK	DKK1gene	CCND1_b1	CCND1_b2
0	0	254	254	1	1	1	1	0	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	1	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	254	1	254	254	254	0	0	254	254	254	254	254	254	0	254	254	254	0	1	1	254	254	254	254	254	1	254	0	0	0	0	0	254	0	0	0

All the compinations have no growth inhibition than the single perturbation except TCF with ERK