dc.contributor.author | Ervaala, Attina | |
dc.contributor.author | Laivuori, Hannele | |
dc.contributor.author | Gissler, Mika | |
dc.contributor.author | Kere, Juha | |
dc.contributor.author | Kivinen, Katja | |
dc.contributor.author | Pouta, Anneli | |
dc.contributor.author | Kajantie, Eero Olavi | |
dc.contributor.author | Heinonen, Seppo | |
dc.contributor.author | Wedenoja, Satu | |
dc.date.accessioned | 2023-05-09T15:10:19Z | |
dc.date.available | 2023-05-09T15:10:19Z | |
dc.date.created | 2022-04-11T09:26:55Z | |
dc.date.issued | 2022 | |
dc.identifier.citation | Pregnancy Hypertension. 2022, 27 59-61. | en_US |
dc.identifier.issn | 2210-7789 | |
dc.identifier.uri | https://hdl.handle.net/11250/3067369 | |
dc.description.abstract | Pregnancies conceived through donor oocytes or sperm show increased risk for preeclampsia. We studied this issue in a preeclampsia case-control cohort (n = 2778), and found overrepresentation of donor cell gestations among women with preeclampsia (14/1627, 0.86%; OR 1.81; 95% CI: 1.07–3.08; P = 0.025) compared to the population data. Moreover, we observed excess of male births from donor cell pregnancies (male-to-female ratio 2.5 vs. 0.97; OR 2.57; 95% CI 1.02–6.36; P = 0.043). Maternal age (36.7 vs. 30.2; P < 0.0001) and preterm deliveries (64% vs. 38%; P = 0.046) distinguished donor cell gestations from other pregnancies with preeclampsia. These results support foreign fetal antigens as modulators of preeclampsia. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Elsevier | en_US |
dc.rights | Navngivelse 4.0 Internasjonal | * |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/deed.no | * |
dc.title | Characteristics of preeclampsia in donor cell gestations | en_US |
dc.title.alternative | Characteristics of preeclampsia in donor cell gestations | en_US |
dc.type | Peer reviewed | en_US |
dc.type | Journal article | en_US |
dc.description.version | publishedVersion | en_US |
dc.source.pagenumber | 59-61 | en_US |
dc.source.volume | 27 | en_US |
dc.source.journal | Pregnancy Hypertension | en_US |
dc.identifier.doi | 10.1016/j.preghy.2021.12.005 | |
dc.identifier.cristin | 2016586 | |
cristin.ispublished | true | |
cristin.fulltext | original | |
cristin.qualitycode | 1 | |