Vitamin D Status among Women in a Rural District of Nepal: Determinants and Association with Metabolic Profile—A Population-Based Study
dc.contributor.author | Yogal, Chandra | |
dc.contributor.author | Borgen, Marianne | |
dc.contributor.author | Shakya, Sunila | |
dc.contributor.author | Karmarcharya, Biraj | |
dc.contributor.author | Koju, Rajendra | |
dc.contributor.author | Mosti, Mats Peder | |
dc.contributor.author | Gustafsson, Miriam K. | |
dc.contributor.author | Åsvold, Bjørn Olav | |
dc.contributor.author | Schei, Berit | |
dc.contributor.author | Stunes, Astrid Kamilla | |
dc.contributor.author | Syversen, Unni | |
dc.date.accessioned | 2023-01-31T10:03:03Z | |
dc.date.available | 2023-01-31T10:03:03Z | |
dc.date.created | 2022-09-01T19:05:26Z | |
dc.date.issued | 2022 | |
dc.identifier.citation | Nutrients. 2022, 14 (11), . | en_US |
dc.identifier.issn | 2072-6643 | |
dc.identifier.uri | https://hdl.handle.net/11250/3047312 | |
dc.description.abstract | Hypovitaminosis D is prevalent worldwide, and especially in South-Asia. According to the Institute of Medicine (IOM), 25(OH)D levels below 30 nmol/L are defined as vitamin D deficiency (VDD) and levels between 30–50 nmol/L as insufficiency (VDI). Besides its role in calcium homeostasis, it has been postulated that vitamin D is involved in metabolic syndrome. Given the scarcity of data on vitamin D status in Nepal, we aimed to examine the prevalence of VDD and VDI, as well as the determinants and association with metabolic parameters (lipids, HbA1c), in a cohort of women in rural Nepal. Altogether, 733 women 48.5 ± 11.7 years of age were included. VDD and VDI were observed in 6.3 and 42.4% of the participants, respectively, and the prevalence increased by age. Women reporting intake of milk and eggs > 2 times weekly had higher 25(OH)D levels than those reporting intake < 2 times weekly. Women with vitamin D levels < 50 nmol/L displayed higher levels of cholesterol, LDL-cholesterol, triglycerides, and HbA1c. Additionally, a regression analysis showed a significant association between hypovitaminosis D, dyslipidemia, and HbA1c elevation. In conclusion, VDI was prevalent and increased with age. Milk and egg intake > 2 times weekly seemed to decrease the risk of VDI. Moreover, hypovitaminosis D was associated with an adverse metabolic profile. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | MDPI | en_US |
dc.rights | Navngivelse 4.0 Internasjonal | * |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/deed.no | * |
dc.title | Vitamin D Status among Women in a Rural District of Nepal: Determinants and Association with Metabolic Profile—A Population-Based Study | en_US |
dc.title.alternative | Vitamin D Status among Women in a Rural District of Nepal: Determinants and Association with Metabolic Profile—A Population-Based Study | en_US |
dc.type | Peer reviewed | en_US |
dc.type | Journal article | en_US |
dc.description.version | publishedVersion | en_US |
dc.source.pagenumber | 0 | en_US |
dc.source.volume | 14 | en_US |
dc.source.journal | Nutrients | en_US |
dc.source.issue | 11 | en_US |
dc.identifier.doi | 10.3390/nu14112309 | |
dc.identifier.cristin | 2048077 | |
cristin.ispublished | true | |
cristin.fulltext | original | |
cristin.qualitycode | 1 |