dc.contributor.author | Ness, Henning Ofstad | |
dc.contributor.author | Ljones, Kristine | |
dc.contributor.author | Gjelsvik, Randi H | |
dc.contributor.author | Tjønna, Arnt Erik | |
dc.contributor.author | Malmo, Vegard | |
dc.contributor.author | Nilsen, Hans-Olav | |
dc.contributor.author | Hollekim-Strand, Siri Marte | |
dc.contributor.author | Dalen, Håvard | |
dc.contributor.author | Høydal, Morten | |
dc.date.accessioned | 2023-01-26T10:25:09Z | |
dc.date.available | 2023-01-26T10:25:09Z | |
dc.date.created | 2022-11-17T10:21:12Z | |
dc.date.issued | 2022 | |
dc.identifier.issn | 2045-2322 | |
dc.identifier.uri | https://hdl.handle.net/11250/3046559 | |
dc.description.abstract | This study evaluated acute cardiac stress after a high-intensity interval training session in patients with type 2 diabetes (T2D) versus healthy controls. High intensity aerobic exercise was performed by 4 × 4-min intervals (90–95% of maximal heart rate), followed by a ramp protocol to peak oxygen uptake. Echocardiography was performed before and 30 min after exercise. Holter electrocardiography monitored heart rhythms 24 h before, during, and 24 h after the exercise. Left atrial end-systolic volume, peak early diastolic mitral annular velocity, and the ratio of peak early to late diastolic mitral inflow velocity were reduced by approximately 18%, 15%, and 31%, respectively, after exercise across groups. Left ventricular end-diastolic wall thickness was the only echo parameter that significantly differed between groups in response to exercise. The T2D group had a rate of supraventricular extrasystoles per hour that was 265% greater than that of the controls before exercise, which remained higher after exercise. A single exhaustive exercise session impaired left ventricular diastolic function in both groups. The findings also indicated impaired right ventricular function in patients with T2D after exercise. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Nature | en_US |
dc.rights | Navngivelse 4.0 Internasjonal | * |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/deed.no | * |
dc.title | Acute effects of high intensity training on cardiac function: a pilot study comparing subjects with type 2 diabetes to healthy controls | en_US |
dc.title.alternative | Acute effects of high intensity training on cardiac function: a pilot study comparing subjects with type 2 diabetes to healthy controls | en_US |
dc.type | Peer reviewed | en_US |
dc.type | Journal article | en_US |
dc.description.version | publishedVersion | en_US |
dc.source.journal | Scientific Reports | en_US |
dc.identifier.doi | 10.1038/s41598-022-12375-2 | |
dc.identifier.cristin | 2075363 | |
dc.relation.project | Norges forskningsråd: 237887 | en_US |
cristin.ispublished | true | |
cristin.fulltext | original | |
cristin.qualitycode | 1 | |