dc.contributor.author | Holta, Ann Christin Reiersølmoen | |
dc.contributor.author | Solvi, Thomas Nordbø | |
dc.contributor.author | Fiksdahl, Anne | |
dc.date.accessioned | 2022-09-19T12:19:24Z | |
dc.date.available | 2022-09-19T12:19:24Z | |
dc.date.created | 2021-02-23T16:01:56Z | |
dc.date.issued | 2021 | |
dc.identifier.citation | Beilstein Journal of Organic Chemistry. 2021, 17 186-192. | en_US |
dc.identifier.issn | 2195-951X | |
dc.identifier.uri | https://hdl.handle.net/11250/3018902 | |
dc.description.abstract | Chiral cyclam (1,4,8,11-tetraazacyclotetradecane) derivatives were synthesized stepwise from chiral mono-Boc-1,2-diamines and (dialkyl)malonyl dichloride via open diamide-bis(N-Boc-amino) intermediates (65–91%). Deprotection and ring closure with a second malonyl unit afforded the cyclam tetraamide precursors (80–95%). The new protocol allowed the preparation of the target cyclam derivatives (53–59%) by a final optimized hydride reduction. Both the open tetraamine intermediates and the cyclam derivatives successfully coordinated with AuCl3 to give moderate to excellent yields (50–96%) of the corresponding novel tetra-coordinated N,N,N,N-Au(III) complexes with alternating five- and six-membered chelate rings. The testing of the catalytic ability of the cyclam-based N,N,N,N-Au(III) complexes demonstrated high catalytic activity of some complexes in selected test reactions (full conversion in 1–24 h, 62–97% product yields). | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Beilstein-Institut | en_US |
dc.rights | Navngivelse 4.0 Internasjonal | * |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/deed.no | * |
dc.title | Au(III) complexes with tetradentate-cyclam-based ligands | en_US |
dc.title.alternative | Au(III) complexes with tetradentate-cyclam-based ligands | en_US |
dc.type | Peer reviewed | en_US |
dc.type | Journal article | en_US |
dc.description.version | publishedVersion | en_US |
dc.source.pagenumber | 186-192 | en_US |
dc.source.volume | 17 | en_US |
dc.source.journal | Beilstein Journal of Organic Chemistry | en_US |
dc.identifier.doi | 10.3762/BJOC.17.18 | |
dc.identifier.cristin | 1892851 | |
dc.relation.project | Norges forskningsråd: 226244 | en_US |
cristin.ispublished | true | |
cristin.fulltext | original | |
cristin.qualitycode | 1 | |