dc.contributor.author | Brenne, Hilde Birgitte Hanssen | |
dc.date.accessioned | 2015-04-14T08:15:07Z | |
dc.date.available | 2015-04-14T08:15:07Z | |
dc.date.issued | 2014 | |
dc.identifier.uri | http://hdl.handle.net/11250/281597 | |
dc.description.abstract | Background: Nasal Continuous Positive Airway Pressure (NCPAP) has recognised benefits
as noninvasive respiratory support in preterm infants. There is now a widespread use of
heated humidified high flow nasal cannula (HHHFNC) as a noninvasive respiratory support in
this population in Newborn Intensive Care Units both nationally and global. There is still a
lack of knowledge of short and long-term clinical effects in the use of HHHFNC, and
especially because it delivers unregulated end expiratory pressure.
Purpose: To test feasibility of a method to measure the work of breathing (WOB) in preterm
infants treated with HHHFNC versus NCPAP.
Material and methods: Electrical activity in the diaphragm (Edi signals) in a randomised
crossover pilot study (2 X 4 hours) with HHHHFNC 6 l/min and NCPAP 2-3cm H2O. Ten
preterm infants with mild to moderate respiratory distress syndrome requiring NCPAP within
48 hours after birth participated.
Outcome: Electrical activity in the diaphragm (Edi peak and Edi min) r espiratory rate and
heart rate.
Results: We found no difference in Edi peak, Edi min or heart rate between the HHHFNC
and NCPAP interventions. Mean respiratory rate was lower during HHHFNC than NCPAP.
No adverse effects.
Conclusion: This randomised crossover pilot study was feasible concerning process,
resources and management. The use of a new and standardised method measuring the neural
drive of the respiration (Edi peak and Edi min) by electromyography is safe and efficient. | nb_NO |
dc.language.iso | eng | nb_NO |
dc.publisher | NTNU | nb_NO |
dc.subject | Masteroppgave | nb_NO |
dc.subject | Anvendt klinisk forskning | nb_NO |
dc.subject | Master i klinisk helsevitenskap | nb_NO |
dc.subject | Edi signals | nb_NO |
dc.subject | Edi peak | nb_NO |
dc.subject | Edi min | nb_NO |
dc.subject | work of breathing | nb_NO |
dc.subject | high flow nasal cannula | nb_NO |
dc.subject | continuous positive airway pressure | nb_NO |
dc.title | The work of breathing (WOB) in preterm infants - Is there a difference in the electrical activity in the diaphragm (Edi signals) and cardiorespiratory parameters during heated humidified nasal cannula (HHHNNC) vs. nasal continuous positive airway pressure (NCPAP)? - A Randomised Crossover Pilot Study | nb_NO |
dc.type | Master thesis | nb_NO |
dc.subject.nsi | VDP::Medical disciplines: 700 | nb_NO |