InterPregGen: Genetic studies of pre-eclampsia in three continents
Morgan, Linda; McGinnis, Ralph; Steinthorsdottir, Valgerdur; Syvatova, Gulnara; Zakhidova, Nodira; Lee, Wai Kwong; Iversen, Ann-Charlotte; Magnus, Per; Walker, James; Casas, Juan Pablo; Sultanov, Saidazim; Laivuori, Hannele
Original version
Norsk Epidemiologi 2014, 24(1-2):141-146Abstract
Pre-eclampsia is a major cause of maternal and fetal mortality in pregnancy. The identification of genetic
variants which predispose to pre-eclampsia demands large DNA collections from affected mothers and
babies and controls, with reliable supporting phenotypic data. The InterPregGen study has assembled a
consortium of researchers from Europe, Central Asia and South America with the aim of elucidating the
genetic architecture of pre-eclampsia. The MoBa collection is playing a vital role in this collaborative
venture, which has the potential to provide new insights into the causes of pre-eclampsia, and provide a
rational basis for novel approaches to prevention and treatment.
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