dc.contributor.author | Foss, Olav A. | |
dc.contributor.author | Mjønes, Patricia | |
dc.contributor.author | Fismen, Silje | |
dc.contributor.author | Christensen, Eidi | |
dc.date.accessioned | 2020-03-04T12:19:07Z | |
dc.date.available | 2020-03-04T12:19:07Z | |
dc.date.created | 2016-03-05T12:14:12Z | |
dc.date.issued | 2016 | |
dc.identifier.citation | Journal of Skin Cancer. 2016, 2016:6146091 . | nb_NO |
dc.identifier.issn | 2090-2905 | |
dc.identifier.uri | http://hdl.handle.net/11250/2645233 | |
dc.description.abstract | Basal cell carcinoma (BCC) is an invasive epithelial skin tumour. The thickness of the outermost epidermal layer of the skin, the stratum corneum (SC), influences drug uptake and penetration into tumour and may thereby affect the response of BCC to topical treatment. The aim was to investigate a possible relationship between the thickness of the SC and that of the viable part of BCC. Histopathological evaluations of the corresponding SC and viable tumour thickness measurements of individual BCCs of different subtypes were explored. A total of 53 BCCs from 46 patients were studied. The median tumour thickness was 1.7 mm (0.8–3.0 mm), with a significant difference between subtypes (𝑝� < 0.001). The SC had a median thickness of 0.3 mm (0.2–0.4 mm), with no difference between tumour subtypes (𝑝� = 0.415). Additionally, no significant association between the thickness of the SC and that of the viable part of the tumour was demonstrated (𝑝� = 0.381). In conclusion our results indicate that SC thickness is relatively constant in BCC. | nb_NO |
dc.language.iso | eng | nb_NO |
dc.publisher | Hindawi Publishing Corporation | nb_NO |
dc.rights | Navngivelse 4.0 Internasjonal | * |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/deed.no | * |
dc.title | Is there a relationship between the stratum corneum thickness and that of the viable parts of tumour cells in basal cell carcinoma? | nb_NO |
dc.type | Journal article | nb_NO |
dc.type | Peer reviewed | nb_NO |
dc.description.version | publishedVersion | nb_NO |
dc.subject.nsi | VDP::Dermatologi og venerologi: 753 | nb_NO |
dc.subject.nsi | VDP::Dermatology and venereology: 753 | nb_NO |
dc.source.pagenumber | 5 | nb_NO |
dc.source.volume | 2016:6146091 | nb_NO |
dc.source.journal | Journal of Skin Cancer | nb_NO |
dc.identifier.doi | 10.1155/2016/6146091 | |
dc.identifier.cristin | 1342405 | |
dc.description.localcode | © 2016 Olav A. Foss et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. | nb_NO |
cristin.unitcode | 1920,9,0,0 | |
cristin.unitcode | 1920,14,0,0 | |
cristin.unitcode | 194,65,15,0 | |
cristin.unitname | Klinikk for ortopedi, revmatologi og hudsykdommer | |
cristin.unitname | Laboratoriemedisinsk klinikk | |
cristin.unitname | Institutt for klinisk og molekylær medisin | |
cristin.ispublished | true | |
cristin.fulltext | original | |
cristin.qualitycode | 1 | |