Risk assessment of "other substances" - L-arginine and arginine alpha-ketoglutarate. Opinion of the Panel on Nutrition, Dietetic Products, Novel Food and Allergy of the Norwegian Scientific Committee for Food Safety
Tell, Grethe S.; Frøyland, Livar; Haugen, Margaretha; Holvik, Kristin; Løvik, Martinus; Strand, Tor A; Iversen, Per Ole
Research report
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http://hdl.handle.net/11250/2461203Utgivelsesdato
2016Metadata
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Sammendrag
The Norwegian Scientific Committee for Food Safety (VKM) has, at the request of the Norwegian Food Safety Authority, assessed the risk of specified doses of L-arginine and arginine alpha-ketoglutarate in food supplements. VKM concludes that:
• In adults (≥18 years), the specified doses of 3000, 3500, 4000, 4500, 5000, 5500 and 6000 mg/day of arginine in food supplements are considered unlikely to cause adverse health effects. The dose 6800 mg/day may represent a risk of adverse health effects.
• In adolescents (14 to <18 years), the specified doses 3000, 3500, 4000, 4500, 5000, 5500 mg/day L-arginine in food supplements are considered unlikely to cause adverse health effects, whereas the doses 6000 and 6800 mg/day may represent a risk of adverse health effects.
• In children (10 to <14 years), the specified doses 3000 and 3500 mg/day L-arginine in food supplements are considered unlikely to cause adverse health effects, whereas the doses 4000, 4500, 5000, 5500, 6000 and 6800 mg/day may represent a risk of adverse health effect.
No dosage of arginine alpha-ketoglutarate in food supplements can be evaluated, due to lack of data.