Mass spectrometry- based metabolite analyses in Streptomyces coelicolor

dc.contributor.advisor	Bruheim, Per	nb_NO
dc.contributor.author	Klubicka, Lidija	nb_NO
dc.date.accessioned	2014-12-19T13:14:40Z
dc.date.available	2014-12-19T13:14:40Z
dc.date.created	2011-10-11	nb_NO
dc.date.issued	2011	nb_NO
dc.identifier	447278	nb_NO
dc.identifier	ntnudaim:6710	nb_NO
dc.identifier.uri	http://hdl.handle.net/11250/245753
dc.description.abstract	A set of mutants with inactivated genes encoding different parts of the butanolide system in Streptomyces coelicolor are cultivated in fermenters. We want to identify and characterize the signaling molecules, gamma- butyrolactones and their role in context to antibiotic production. Extracellular concentrations of the gamma- butyrolactones are determined by LC-MS. Also, intracellular metabolites in a mutant with an inactivated gene responsible for a part of the nitrogen metabolism in S.coelicolor are analysed using GC-MS.	nb_NO
dc.language	eng	nb_NO
dc.publisher	Institutt for bioteknologi	nb_NO
dc.subject	ntnudaim:6710	no_NO
dc.subject	MBIOT5 Bioteknologi	no_NO
dc.subject	Molekylærbiologi	no_NO
dc.title	Mass spectrometry- based metabolite analyses in Streptomyces coelicolor	nb_NO
dc.type	Master thesis	nb_NO
dc.source.pagenumber	106	nb_NO
dc.contributor.department	Norges teknisk-naturvitenskapelige universitet, Fakultet for naturvitenskap og teknologi, Institutt for bioteknologi	nb_NO