dc.contributor.author | Mai, Xiao-Mei | |
dc.contributor.author | Chen, Yue | |
dc.contributor.author | Camargo, Carlos Arthuro | |
dc.contributor.author | Langhammer, Arnulf | |
dc.date.accessioned | 2017-06-12T07:04:47Z | |
dc.date.available | 2017-06-12T07:04:47Z | |
dc.date.created | 2012-10-03T14:35:41Z | |
dc.date.issued | 2012 | |
dc.identifier.citation | American Journal of Epidemiology. 2012, 175 (10), 1029-1036. | nb_NO |
dc.identifier.issn | 0002-9262 | |
dc.identifier.uri | http://hdl.handle.net/11250/2445685 | |
dc.description.abstract | Experimental studies suggest that vitamin D modulates the activity of adipocytes. The authors examined baseline serum 25-hydroxyvitamin D (25(OH)D) level in relation to prevalent and cumulative incident obesity in Norway. A cohort of 25,616 adults aged 19–55 years participated in both the second and third surveys of the Nord-Trøndelag Health Study (HUNT 2 (1995–1997) and HUNT 3 (2006–2008)). Serum 25(OH)D levels measured at baseline and anthropometric measurements taken at both baseline and follow-up were available for a random sample of 2,460 subjects. Overall, 40% of the 2,460 subjects had a serum 25(OH)D level less than 50.0 nmol/L, and 37% had a level of 50.0–74.9 nmol/L. The prevalence and cumulative incidence of obesity, defined as body mass index (weight (kg)/height (m)2) ≥30, were 12% and 15%, respectively. Lower serum 25(OH)D level was associated with a higher prevalence of obesity. In the 2,165 subjects with baseline BMI less than 30, a serum 25(OH)D level less than 50.0 nmol/L was associated with a significantly increased odds ratio for incident obesity during follow-up (adjusted odds ratio = 1.73, 95% confidence interval: 1.24, 2.41). When prevalent and incident obesity were classified according to waist circumference (≥88 cm for women, ≥102 cm for men), similar results were obtained. In addition to prevalent obesity, a serum 25(OH)D level less than 50.0 nmol/L was significantly associated with new-onset obesity in adults. | nb_NO |
dc.language.iso | eng | nb_NO |
dc.publisher | Oxford University Press | nb_NO |
dc.title | Cross-Sectional and Prospective Cohort Study of Serum 25-Hydroxyvitamin D Level and Obesity in Adults | nb_NO |
dc.type | Journal article | nb_NO |
dc.type | Peer reviewed | nb_NO |
dc.description.version | acceptedVersion | nb_NO |
dc.source.pagenumber | 1029-1036 | nb_NO |
dc.source.volume | 175 | nb_NO |
dc.source.journal | American Journal of Epidemiology | nb_NO |
dc.source.issue | 10 | nb_NO |
dc.identifier.doi | 10.1093/aje/kwr456 | |
dc.identifier.cristin | 948451 | |
dc.relation.project | Norges forskningsråd: 201895 | nb_NO |
dc.description.localcode | American Journal of Epidemiology © The Author 2012. Published by Oxford University Press on behalf of the Johns Hopkins Bloomberg School of Public Health. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com. This is the authors' accepted and refereed manuscript to the article. | nb_NO |
cristin.unitcode | 194,65,20,0 | |
cristin.unitname | Institutt for samfunnsmedisin | |
cristin.ispublished | true | |
cristin.fulltext | postprint | |
cristin.qualitycode | 2 | |