dc.contributor.author | Thomsen, Per Hove | |
dc.contributor.author | Torp, Nor Christian | |
dc.contributor.author | Dahl, Kitty | |
dc.contributor.author | Christensen, K | |
dc.contributor.author | Englyst, Inger | |
dc.contributor.author | Melin, Karin | |
dc.contributor.author | Nissen, Judith Becker | |
dc.contributor.author | Valderhaug, Robert | |
dc.contributor.author | Weidle, Bernhard | |
dc.contributor.author | Skarphedinsson, Gudmundur Águst | |
dc.contributor.author | von bahr, p.l. | |
dc.contributor.author | Ivarsson, Tord | |
dc.contributor.author | Hybel, Katja A. | |
dc.date.accessioned | 2015-09-29T11:17:47Z | |
dc.date.accessioned | 2015-10-15T08:22:59Z | |
dc.date.available | 2015-09-29T11:17:47Z | |
dc.date.available | 2015-10-15T08:22:59Z | |
dc.date.issued | 2013 | |
dc.identifier.citation | Child and Adolescent Psychiatry and Mental Health 2013, 7(1) | nb_NO |
dc.identifier.issn | 1753-2000 | |
dc.identifier.uri | http://hdl.handle.net/11250/2356207 | |
dc.description | - | nb_NO |
dc.description.abstract | BACKGROUND: This paper describes and discusses the methodology of the Nordic long-term OCD-treatment study (NordLOTS). The purpose of this effectiveness study was to study treatment outcome of CBT, to identify CBT non- or partial responders and to investigate whether an increased number of CBT-sessions or sertraline treatment gives the best outcome; to identify treatment refractory patients and to investigate the outcome of aripiprazole augmentation; to study the outcome over a three year period for each responder including the risk of relapse, and finally to study predictors, moderators and mediators of treatment response.
METHODS: Step 1 was an open and uncontrolled clinical trial with CBT, step 2 was a controlled, randomised non-blinded study of CBT non-responders from step 1. Patients were randomized to receive either sertraline plus CBT-support or continued and modified CBT. In step 3 patients who did not respond to either CBT or sertraline were treated with aripiprazole augmentation to sertraline.
CONCLUSIONS: This multicenter trial covering three Scandinavian countries is going to be the largest CBT-study for paediatric OCD to date. It is not funded by industry and tries in the short and long-term to answer the question whether further CBT or SSRI is better in CBT non-responders. | nb_NO |
dc.language.iso | eng | nb_NO |
dc.publisher | BioMed Central | nb_NO |
dc.title | The Nordic long-term OCD treatment study (NordLOTS): rationale, design, and methods | nb_NO |
dc.type | Journal article | nb_NO |
dc.type | Peer reviewed | en_GB |
dc.date.updated | 2015-09-29T11:17:47Z | |
dc.source.volume | 7 | nb_NO |
dc.source.journal | Child and Adolescent Psychiatry and Mental Health | nb_NO |
dc.source.issue | 1 | nb_NO |
dc.identifier.doi | 10.1186/1753-2000-7-41 | |
dc.identifier.cristin | 1151830 | |
dc.description.localcode | © 2013 Thomsen et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. | nb_NO |