Blar i Institutt for sirkulasjon og bildediagnostikk på tidsskrift "Physiological Reports"
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Abdominal aerobic endurance exercise reveals spot reduction exists : a randomized controlled trial
(Peer reviewed; Journal article, 2023)The existence of spot reduction, exercise-induced local body fat reduction, has been debated for half a century. Although the evidence is equivocal, no study has applied aerobic endurance training closely matching interventions ... -
Bronchial microdialysis monitoring of inflammatory response in open abdominal aortic aneurysm repair; an observational study.
(Journal article; Peer reviewed, 2017)Aortic surgery results in ischemia–reperfusion injury that induces an inflammatory response and frequent complications. The magnitude of the inflammatory response in blood and bronchi may be associated with the risk of ... -
Cardiac power integral: a new method for monitoring cardiovascular performance
(Journal article; Peer reviewed, 2013)Cardiac power (PWR) is the continuous product of flow and pressure in the proximal aorta. Our aim was to validate the PWR integral as a marker of left ventricular energy transfer to the aorta, by comparing it to stroke ... -
Cardiac surgery does not lead to loss of oscillatory components in circulatory signals
(Peer reviewed; Journal article, 2020)The circulatory system is oscillatory in its nature. Oscillatory components linked to physiological processes and underlying regulatory mechanisms are identifiable in circulatory signals. Autonomic regulation is essential ... -
Comparison of left versus right atrial myocardium in patients with sinus rhythm or atrial fibrillation - an assessment of mitochondrial function and microRNA expression.
(Journal article; Peer reviewed, 2014)Several of the cellular alterations involved in atrial fibrillation (AF) may be linked to mitochondrial function and altered microRNA (miR) expression. A majority of studies on human myocardium involve right atrial (RA) ... -
Effects of hyperbaric oxygen preconditioning on cardiac stress markers after simulated diving.
(Journal article; Peer reviewed, 2013)Hyperbaric oxygen preconditioning (HBO-PC) can protect the heart from injury during subsequent ischemia. The presence of high loads of venous gas emboli (VGE) induced by a rapid ambient pressure reduction on ascent from ... -
Evaluating PAI-1 as a biomarker for stress in diving: human serum total PAI-1 is unaltered after 2 h dry exposures to 280 kPa hyperbaric air
(Journal article; Peer reviewed, 2015)Plasminogen activator inhibitor (PAI-1) is induced in the vasculature and secreted into the vascular lumen in response to inflammation and oxidative stress. We have previously reported a fivefold increase in plasma PAI-1 ... -
Identification of exercise-regulated genes in mice exposed to cigarette smoke
(Peer reviewed; Journal article, 2022)Cigarette smoke (CS) is the major risk factor for COPD and is linked to cardiopulmonary dysfunction. Exercise training as part of pulmonary rehabilitation is recommended for all COPD patients. It has several physiological ... -
Minimally invasive beat-by-beat monitoring of cardiac power in normal hearts and during acute ventricular dysfunction
(Journal article; Peer reviewed, 2016)Cardiac power, the product of aortic flow and blood pressure, appears to be a fundamental cardiovascular parameter. The simplified version named cardiac power output (CPO), calculated as the product of cardiac output (CO) ... -
Post Cardiac Surgery Stunning Reduces Stroke Work, but Leaves Cardiac Power Output Unchanged in Patients with Normal Ejection Fraction
(Journal article; Peer reviewed, 2018)This study assesses positional changes in cardiac power output and stroke work compared to classic haemodynamic variables, measured before and after elective coronary artery bypass graft surgery. The hypothesis was that ... -
Reduced reactive hyperemia may explain impaired flow-mediated dilation after on-pump cardiac surgery
(Journal article; Peer reviewed, 2017)In previous studies, Flow Mediated Dilation (FMD) was used to study the effect of cardiac surgery on endothelial function. This study investigated the effect of on‐pump cardiac surgery on FMD and reactive hyperemia. The ... -
Reliability of forearm oxygen uptake during handgrip exercise : assessment by ultrasonography and venous blood gas
(Journal article; Peer reviewed, 2018)Assessment of forearm oxygen uptake (O2) during handgrip exercise is a keenly investigated concept for observing small muscle mass metabolism. Although a combination of Doppler ultrasound measurements of brachial artery ... -
S100B and NSE serum concentrations after simulated diving in rats
(Journal article; Peer reviewed, 2015)The purpose of this study was to assess whether one could detect S100 calcium‐binding protein B (S100B) and neuron‐specific enolase (NSE) in serum of rats after a simulated dive breathing air, with the main hypothesis that ... -
The coherence of macrocirculation, microcirculation, and tissue metabolic response during nontraumatic hemorrhagic shock in swine
(Journal article; Peer reviewed, 2017)Hemorrhagic shock is clinically observed as changes in macrocirculatory indices, while its main pathological constituent is cellular asphyxia due to microcirculatory alterations. The coherence between macro‐ and microcirculatory ...