Blar i Institutt for klinisk og molekylær medisin på tittel
Viser treff 2579-2598 av 3434
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Protocol of a randomised, controlled trial comparing immediate curative therapy with conservative treatment in men aged ≥75 years with non-metastatic high-risk prostate cancer (SPCG 19/GRand-P)
(Peer reviewed; Journal article, 2024)Background Older men (aged ≥75 years) with high risk, non-metastatic prostate cancer (PCa) are increasingly treated with curative therapy (surgery or radiotherapy). However, it is unclear if curative therapy prolongs ... -
Proton pump inhibitors and fracture risk. The HUNT study, Norway.
(Journal article; Peer reviewed, 2019)Summary Proton pump inhibitors (PPIs) have been linked to increased risk of fracture; the data have, however, been diverging. We did not find any increased risk of fractures among users of PPIs in a Norwegian population ... -
Protozoan ALKBH8 Oxygenases Display both DNA Repair and tRNA Modification Activities
(Journal article; Peer reviewed, 2014)The ALKBH family of Fe(II) and 2-oxoglutarate dependent oxygenases comprises enzymes that display sequence homology to AlkB from E. coli, a DNA repair enzyme that uses an oxidative mechanism to dealkylate methyl and etheno ... -
Pseudo-anaphylaxis to polyethylene glycol (PEG)-coated liposomes: Roles of anti-PEG IgM and complement activation in a porcine model of human infusion reactions
(Journal article; Peer reviewed, 2019)Polyethylene glycol (PEG)-coated nanopharmaceuticals can cause mild to severe hypersensitivity reactions (HSRs), which can occasionally be life threatening or even lethal. The phenomenon represents an unsolved immune barrier ... -
Pseudo-T2 mapping for normalization of T2-weighted prostate MRI
(Peer reviewed; Journal article, 2022)Objective Signal intensity normalization is necessary to reduce heterogeneity in T2-weighted (T2W) magnetic resonance imaging (MRI) for quantitative analysis of multicenter data. AutoRef is an automated dual-reference ... -
Psoriasis and associated variables in classification and outcome of juvenile idiopathic arthritis - an eight-year follow-up study
(Journal article; Peer reviewed, 2017)Background To study the impact of psoriasis and features associated with psoriasis on classification and outcome in a population-based follow-up cohort of children with juvenile idiopathic arthritis (JIA). Methods In ... -
Psoriasis pathogenesis – Pso p27 constitutes a compact structure forming large aggregates
(Journal article; Peer reviewed, 2015)Psoriasis is a chronic inflammatory skin disease. The absence of microbial organisms as potential causal agents has given rise to the hypothesis that the inflammation is due to an autoimmune reaction. The defined inflamed ... -
Psychiatric Disorders and General Functioning in Low Birthweight Adults: A Longitudinal Study
(Journal article; Peer reviewed, 2017)OBJECTIVE: To examine psychiatric morbidity and overall functioning in adults born with low birth weight compared with normal birth weight controls at age 26 years and to study longitudinal trajectories of psychiatric ... -
Psychiatric disorders in individuals born very preterm / very low-birth weight: An individual participant data (IPD) meta-analysis
(Peer reviewed; Journal article, 2021)Background Data on psychiatric disorders in survivors born very preterm (VP; <32 weeks) or very low birthweight (VLBW; <1500 g) are sparse. We compared rates of psychiatric diagnoses between VP/VLBW and term-born, normal ... -
Psychiatric morbidity, somatic comorbidity and substance use in an adolescent psychiatric population at 3-year follow-up
(Peer reviewed; Journal article, 2020)Knowledge is scarce on the course of psychiatric disorders in adolescence. We aimed to assess changes in the frequency of psychiatric disorders, somatic disorders, pain, and substance use in a clinical psychiatric cohort ... -
Psychiatric Symptoms and Risk Factors in Adults Born Preterm with Very Low Birthweight or Born Small for Gestational Age at Term
(Journal article; Peer reviewed, 2019)Background We aimed to examine psychiatric symptoms in adults born preterm with very low birthweight or born at term small for gestational age compared with normal birthweight peers, and examine associations with perinatal ... -
Psychomotor skills assessment by motion analysis in minimally invasive surgery on an animal organ
(Journal article; Peer reviewed, 2017)Background: A high level of psychomotor skills is required to perform minimally invasive surgery (MIS) safely. To be able to measure these skills is important in the assessment of surgeons, as it enables constructive ... -
Psychosocial Vulnerability Among Patients Contacting a Norwegian Sexual Assault Center
(Journal article, 2016)In this study, the objective was to assess the occurrence of specific vulnerability factors among adult and adolescent females attending a Norwegian sexual assault center (SAC). We also explored assault characteristics and ... -
Psykisk helse hos personer med moderat lav IQ
(Master thesis, 2016)Introduksjon: Kognitive funksjoner er definert som funksjoner som har betydning for erkjennelse, tenkning og kunnskapservervelse1. Intelligens er menneskers evne til nettopp det å tenke, oppfatte, forstå og erfare2. IQ ... -
PUFA-induced stress in cancer cells –autophagy as a potential determinant for cell survival
(Master thesis, 2010)Polyunsaturated fatty acids (PUFAs) show diverse effects on cancer cells. The explanation to why some cancer cells seem to be sensitive of PUFAs and some do not is, however, still a debated topic. Autophagy is a disease ... -
Pulmonary manifestations and progression of lung disease in juvenile-onset mixed connective tissue disease
(Journal article; Peer reviewed, 2019)Objective. To assess the occurrence and extent of interstitial lung disease (ILD) in patients with juvenile mixed connective tissue disease (JMCTD), compare pulmonary function in patients and matched controls, study ... -
Put your weight behind it—Effect of body mass index on the active second stage of labour: A retrospective cohort study
(Journal article; Peer reviewed, 2022) -
PyRanges: efficient comparison of genomic intervals in Python
(Journal article; Peer reviewed, 2019)Complex genomic analyses often use sequences of simple set operations like intersection, overlap and nearest on genomic intervals. These operations, coupled with some custom programming, allow a wide range of analyses to ...