Browsing NTNU Open by Author "Schneider, Olha"
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An orthogonal system for heterologous expression of actinobacterial lasso peptides in Streptomyces hosts
Mevaere, Jimmy; Goulard, Christophe; Schneider, Olha; Sekurova, Olga N.; Ma, Haiyan; Zirah, Severine; Afonso, Carlos; Rebuffat, Sylvie; Zotchev, Sergey B; Li, Yanyan (Journal article; Peer reviewed, 2018)Lasso peptides are ribosomally synthesized and post-translationally modified peptides produced by bacteria. They are characterized by an unusual lariat-knot structure. Targeted genome scanning revealed a wide diversity of ... -
Genome Mining of actinomycete bacteria for new natural products
Schneider, Olha (Doctoral theses at NTNU;2018:348, Doctoral thesis, 2018)Here, the genome data of seven different strains of Streptomyces and a strain from the Actinoalloteichus genus were analysed for the presence of biosynthetic gene clusters (BGC) encoding for potential new natural products ... -
Genome Mining of Streptomyces sp. YIM 130001 Isolated From Lichen Affords New Thiopeptide Antibiotic
Schneider, Olha; Simic, Nebojsa; Aachmann, Finn Lillelund; Rückert, Christian; Kristiansen, Kåre Andre; Kalinowski, Jörn; Jiang, Yi; Wang, Lisong; Jiang, Cheng-Lin; Lale, Rahmi; Zotchev, Sergey B (Journal article; Peer reviewed, 2018)Streptomyces bacteria are recognized as an important source for antibiotics with broad applications in human medicine and animal health. Here, we report the isolation of a new lichen-associating Streptomyces sp. YIM 130001 ... -
Genomics-based insights into the biosynthesis and unusually high accumulation of free fatty acids by Streptomyces sp. NP10
Schneider, Olha; Ilic-Tomic, Tatjana; Rückert, Christian; Kalinowski, Jörn; Gencic, Marija S; Zivkovic, Milena Z; Stankovic, Nada; Radulovic, Niko S; Vasiljevic, Branka; Nikodinovic-Runic, Jasmina; Zotchev, Sergey B (Journal article; Peer reviewed, 2018)Streptomyces sp. NP10 was previously shown to synthesize large amounts of free fatty acids (FFAs). In this work, we report the first insights into the biosynthesis of these fatty acids (FAs) gained after genome sequencing ... -
Methylotrophic Bacillus methanolicus encodes two chromosomal and one plasmid born NAD+ dependent methanol dehydrogenase paralogs with different catalytic and biochemical properties
Krog, Anne; Heggeset, Tonje Marita Bjerkan; Müller, Jonas E.N.; Kupper, Christiane E.; Schneider, Olha; Vorholt, Julia A.; Ellingsen, Trond Erling; Brautaset, Trygve (Journal article; Peer reviewed, 2013-03-19)Bacillus methanolicus can utilize methanol as the sole carbon source for growth and it encodes an NAD+-dependent methanol dehydrogenase (Mdh), catalyzing the oxidation of methanol to formaldehyde. Recently, the genomes of ...