Blar i NTNU Open på forfatter "Heerschap, Arend"
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In vivo 31P MRSI for metabolic profiling of human breast cancer xenografts
Esmaeili, Morteza; Moestue, Siver Andreas; Hamans, Bob C.; Veltien, Andor; Kristian, Alexandr; Engebråten, Olav; Mælandsmo, Gunhild; Gribbestad, Ingrid S; Bathen, Tone; Heerschap, Arend (Journal article; Peer reviewed, 2015)Purpose To study cancer associated with abnormal metabolism of phospholipids, of which several have been proposed as biomarkers for malignancy or to monitor response to anticancer therapy. We explored 3D 31P magnetic ... -
Increased levels of choline metabolites are an early marker of docetaxel treatment response in BRCA1-mutated mouse mammary tumors: an assessment by ex vivo proton magnetic resonance spectroscopy
van Asten, Jack JA; Vettukattil, Muhammad Riyas; Buckle, Tessa; Rottenberg, Sven; Leeuwen, Fijs van; Bathen, Tone Frost; Heerschap, Arend (Journal article; Peer reviewed, 2015)Abstract Background Docetaxel is one of the most frequently used drugs to treat breast cancer. However, resistance or incomplete response to docetaxel is a major challenge. The aim of this study was to utilize MR ... -
Simultaneous 18F-fluciclovine Positron Emission Tomography and Magnetic Resonance Spectroscopic Imaging of Prostate Cancer
Esmaeili, Morteza; Tayari, Nassim; Scheenen, Tom WJ; Elschot, Mattijs; Sandsmark, Elise; Bertilsson, Helena; Heerschap, Arend; Selnæs, Kirsten Margrete; Bathen, Tone Frost (Journal article; Peer reviewed, 2018)Purpose: To investigate the associations of metabolite levels derived from magnetic resonance spectroscopic imaging (MRSI) and 18F-fluciclovine positron emission tomography (PET) with prostate tissue characteristics. Methods: ... -
Tissue microstructure is linked to MRI parameters and metabolite levels in prostate cancer
Selnæs, Kirsten Margrete; Vettukattil, Muhammad Riyas; Bertilsson, Helena; Wright, Alan J.; Heerschap, Arend; Angelsen, Anders; Tessem, May-Britt; Bathen, Tone Frost (Peer reviewed; Journal article, 2016)Introduction: Magnetic resonance imaging (MRI) can portray spatial variations in tumor heterogeneity, architecture, and its microenvironment in a non-destructive way. The objective of this study was to assess the relationship ...