• Ancient Evolutionary Trade-Offs between Yeast Ploidy States 

      Zörgö, Enikö Beatrix; Chwialkowska, Karolina; Gjuvsland, Arne Bjørke; Garre, Elena; Sunnerhagen, Per; Liti, Gianni; Blomberg, Anders; Omholt, Stig W; Warringer, Jonas (Journal article; Peer reviewed, 2013)
      The number of chromosome sets contained within the nucleus of eukaryotic organisms is a fundamental yet evolutionarily poorly characterized genetic variable of life. Here, we mapped the impact of ploidy on the mitotic ...
    • Concerted Evolution of Life Stage Performances Signals Recent Selection on Yeast Nitrogen Use 

      Ibstedt, Sebastian; Stenberg, Simon; Bages, Sara; Gjuvsland, Arne Bjørke; Salinas, Francisco; Kourtchenko, Olga; Samy, Jeevan K.A.; Blomberg, Anders; Omholt, Stig William; Liti, Gianni; Beltran, Gemma; Warringer, Jonas (Journal article; Peer reviewed, 2015)
      Exposing natural selection driving phenotypic and genotypic adaptive differentiation is an extraordinary challenge. Given that an organism’s life stages are exposed to the same environmental variations, we reasoned that ...
    • Disentangling genetic and epigenetic determinants of ultrafast adaptation 

      Gjuvsland, Arne Bjørke; Zörgö, Enikö Beatrix; Antony Samy, Jeevan Karloss; Stenberg, Simon; Demirsoy, Ibrahim H; Roque, Francisco; Maciaszczyk-Dziubinska, Ewa; Migocka, Magdalena; Alonso-Perez, Elisa; Zackrisson, Martin; Wysocki, Robert; Tamas, Markus J; Jonassen, Inge; Omholt, Stig William; Warringer, Jonas (Journal article; Peer reviewed, 2016)
      A major rationale for the advocacy of epigenetically mediated adaptive responses is that they facilitate faster adaptation to environmental challenges. This motivated us to develop a theoretical–experimental framework for ...
    • Genetically controlled mtDNA deletions prevent ROS damage by arresting oxidative phosphorylation 

      Stenberg, Ulf Simon; Li, Jing; Gjuvsland, Arne Bjørke; Persson, Karl; Demitz-Helin, Erik; Gonzalez-Pena, Carles; Yue, Jia-Xing; Gilchrist, Ciaran; Ärengård, Timmy; Ghiaci, Payam; Larsson-Berglund, Lisa; Zackrisson, Martin; Smits, Silvana; Hallin, Johan; Höög, Johanna L.; Molin, Mikael; Liti, Gianni; Omholt, Stig William; Warringer, Jonas (Journal article; Peer reviewed, 2022)
    • Predictive evolution of metabolic phenotypes using model-designed environments 

      Jouhten, Paula; Konstantinidis, Dimitrios; Pereira, Filipa; Andrejev, Sergej; Grkovska, Kristina; Castillo, Sandra; Ghiachi, Payam; Beltran, Gemma; Almaas, Eivind; Mas, Albert; Warringer, Jonas; Gonzalez, Ramon; Morales, Pilar; Patil, Kiran R. (Peer reviewed; Journal article, 2022)
      Adaptive evolution under controlled laboratory conditions has been highly effective in selecting organisms with beneficial phenotypes such as stress tolerance. The evolution route is particularly attractive when the organisms ...
    • Scan-o-matic: High-Resolution Microbial Phenomics at a Massive Scale 

      Zackrisson, Martin; Hallin, Johan; Ottoson, Lars-Göran; Dahl, Peter; Fernandez-Parada, Esteban; Landström, Erik; Fernandez-Ricaud, Luciano; Kaferle, Petra; Skyman, Andreas; Stenberg, Simon; Omholt, Stig William; Petrovic, Uros; Warringer, Jonas; Blomberg, Anders (Journal article; Peer reviewed, 2016)
      The capacity to map traits over large cohorts of individuals-phenomics-lags far behind the explosive development in genomics. For microbes, the estimation of growth is the key phenotype because of its link to fitness. We ...