• Preeclampsia and cardiovascular disease share genetic risk factors on chromosome 2q22 

      Løset, Mari; Johnson, Matthew P.; Melton, Philip E.; Ang, Wei; Huang, Rae-Chi; Mori, Trevor; Beilin, Lawrence J.; Pennell, Craig E.; Roten, Linda Tømmerdal; Iversen, Ann-Charlotte; Austgulen, Rigmor; East, Christine E.; Blangero, John; Brennecke, Shaun P.; Moses, Eric K (Journal article; Peer reviewed, 2014)
      Objective Four putative single nucleotide polymorphism (SNP) risk variants at the preeclampsia susceptibility locus on chromosome 2q22; rs2322659 (LCT), rs35821928 (LRP1B), rs115015150 (RND3) and rs17783344 (GCA), were ...
    • Refined phenotyping identifies links between preeclampsia and related diseases in a Norwegian preeclampsia family cohort 

      Thomsen, Liv Cecilie Vestrheim; Melton, Philip E.; Tollaksen, Kjersti; Lyslo, Ingvill; Roten, Linda Tømmerdal; Odland, Maria Lisa; Strand, Kristin Melheim; Nygård, Ottar; Sun, Chen; Iversen, Ann-Charlotte; Austgulen, Rigmor; Moses, Eric; Bjørge, Line (Peer reviewed; Journal article, 2015)
      Objective: Preeclampsia is a complex genetic disease of pregnancy with a heterogenous presentation, unknown cause and potential severe outcomes for both mother and child. Preeclamptic women have increased risk for ...
    • The antihypertensive MTHFR gene polymorphism rs17367504-G is a possible novel protective locus for preeclampsia 

      Thomsen, Liv Cecilie Vestrheim; McCarthy, Nina; Melton, Philip E.; Cadby, Gemma; Austgulen, Rigmor; Nygård, Ottar; Johnson, Matthew P; Brennecke, Shaun P.; Moses, Eric K; Bjørge, Line; Iversen, Ann-Charlotte (Journal article; Peer reviewed, 2016)
      Objective: Preeclampsia is a complex heterogeneous disease commonly defined by newonset hypertension and proteinuria in pregnancy. Women experiencing preeclampsia have increased risk for cardiovascular diseases (CVD) later ...