Blar i NTNU Open på forfatter "Hofsli, Eva"
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The prognostic value of pre-treatment circulating biomarkers of systemic inflammation (CRP, dNLR, YKL-40, and IL-6) in vulnerable older patients with metastatic colorectal cancer receiving palliative chemotherapy—The Randomized NORDIC9-Study
Liposits, Gabor; Skuladottir, Halla; Ryg, Jesper; Winther, Stine Brændegaard; Möller, Sören; Hofsli, Eva; Shah, Carl-Henrik; Poulsen, Laurids Østergaard; Berglund, Åke; Qvortrup, Camilla; Osterlund, Pia; Johansen, Julia S.; Glimelius, Bengt; Sorbye, Halfdan; Pfeiffer, Per (Peer reviewed; Journal article, 2022)Appropriate patient selection for palliative chemotherapy is crucial in patients with metastatic colorectal cancer (mCRC). We investigated the prognostic value of C-reactive protein (CRP), derived neutrophil-to-lymphocyte ... -
Quality of life in vulnerable older patients with metastatic colorectal cancer receiving palliative chemotherapy—the randomized nordic9-study
Liposits, Gabor; Eshoj, Henrik; Möller, Sören; Winther, Stine Brændegaard; Skuladottir, Halla; Ryg, Jesper; Hofsli, Eva; Shah, Carl-Henrik; Poulsen, Laurids Østergaard; Berglund, Åke; Qvortrup, Camilla; Österlund, Pia; Glimelius, Bengt; Sorbye, Halfdan; Pfeiffer, Per (Peer reviewed; Journal article, 2021)Bowel cancer is one of the leading cancer-types in both sexes worldwide. Despite that most new cases and deaths occur in people aged 70 years or older, few clinical trials have investigated the best way to administer ... -
Retrospektiv studie av pasienter med inoperabel lokalavansert eller metastatisk pancreascancer behandlet ved St. Olavs Hospital i tidsperioden 2012-2015
Bogen, Guro Bergsli; Fjellstad, Kjesti Egeland (Master thesis, 2017)Bakgrunn: Cancer pancreatis er i stor grad en letal tilstand, og majoriteten av pasientene er i ikke-kurativ setting på diagnosetidspunktet. Det har de senere årene kommet nye kjemoterapiregimer som gir håp om bedre ... -
Sex hormones and sperm parameters after adjuvant oxaliplatin-based treatment for colorectal cancer
Falk, Philip; Severin, Mira; Berglund, Åke; Guren, Marianne; Hofsli, Eva; Österlund, Pia; Tandberg, Anne; Eberhard, Jakob; Sorbye, Halfdan (Peer reviewed; Journal article, 2022)Background The incidence of colorectal cancer (CRC) in individuals of fertile age is increasing. Oxaliplatin is a cornerstone treatment in the adjuvant setting for stage III and high-risk stage II CRC. Limited data exist ... -
Small RNA expression from viruses, bacteria and human miRNAs in colon cancer tissue and its association with microsatellite instability and tumor location
Mjelle, Robin; Sjursen, Wenche; Thommesen, Liv; Sætrom, Pål; Hofsli, Eva (Journal article; Peer reviewed, 2019)Background MicroRNAs (miRNA) and other small RNAs are frequently dysregulated in cancer and are promising biomarkers for colon cancer. Here we profile human, virus and bacteria small RNAs in normal and tumor tissue from ... -
sMETASeq: combined profiling of microbiota and host small RNAs
Mjelle, Robin; Aass, Kristin Roseth; Sjursen, Wenche; Hofsli, Eva; Sætrom, Pål (Peer reviewed; Journal article, 2020)Understanding microbial communities' roles in human health and disease requires methods that accurately characterize the microbial composition and their activity and effects within human biological samples. We present ... -
Ultrasound and microbubble-enhanced therapy of Gastrointestinal tumors using conventional cytotoxic drugs in preclinical and clinical settings
Haram, Margrete (Doctoral theses at NTNU;2024:94, Doctoral thesis, 2024)Pancreatic ducal adenocarcinoma (PDAC) remains one of the deadliest cancers, with a very short life expectancy. Together with late diagnosis and aggressive biology, chemoresistance is one important cause of poor survival. ...