Blar i NTNU Open på forfatter "Vettukattil, Muhammad Riyas"
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Anti-vascular effects of the cytosolic phospholipase A2 inhibitor AVX235 in a patient-derived basal-like breast cancer model
Kim, Eugene; Tunset, Hanna Maja; Cebulla, Jana; Vettukattil, Muhammad Riyas; Helgesen, Heidi; Feuerherm, Astrid Jullumstrø; Engebråten, Olav; Mælandsmo, Gunhild; Johansen, Berit; Moestue, Siver Andreas (Journal article; Peer reviewed, 2016)Background: Group IVA cytosolic phospholipase A2 (cPLA2α) plays an important role in tumorigenesis and angiogenesis. It is overexpressed in basal-like breast cancer (BLBC), which is aggressive and usually triple-negative, ... -
Early metabolite changes after melatonin treatment in neonatal rats with hypoxic-ischemic brain injury studied by in-vivo 1H MR spectroscopy
Berger, Hester Rijkje; Nyman, Axel Karl Gottfrid; Morken, Tora Sund; Vettukattil, Muhammad Riyas; Brubakk, Ann-Mari; Widerøe, Marius (Journal article; Peer reviewed, 2017)Melatonin is a promising neuroprotective agent after perinatal hypoxic-ischemic (HI) brain injury. We used in-vivo 1H magnetic resonance spectroscopy to investigate effects of melatonin treatment on brain metabolism after ... -
Evaluation of metabolomic changes during neoadjuvant chemotherapy combined with bevacizumab in breast cancer using MR spectroscopy
Euceda, Leslie R.; Haukaas, Tonje Husby; Giskeødegård, Guro F.; Vettukattil, Muhammad Riyas; Engel, Jasper; Silwal-Pandit, Laxmi; Lundgren, Steinar; Borgen, Elin; Garred, Øystein; Postma, Geert; Buydens, Lutgarde M.C.; Børresen-Dale, Anne-Lise; Engebråten, Olav; Bathen, Tone Frost (Journal article; Peer reviewed, 2017)Introduction Metabolomics investigates biochemical processes directly, potentially complementing transcriptomics and proteomics in providing insight into treatment outcome. Objectives This study aimed to use ... -
Identification and Characterization of Biomarkers using Magnetic Resonance Metabolomics: – Metabolic portraits of cancers and aerobic fitness
Vettukattil, Muhammad Riyas (Doktoravhandlinger ved NTNU, 1503-8181; 2013:234, Doctoral thesis, 2013)Identifisering og karakterisering av biomarkører ved bruk av magnetisk resonans metabolomics Kreft og kardiovaskulære sykdommer er ledende dødsårsaker i industriland og i mange utviklingsland. De eksisterende kliniske og ... -
Impact of Freezing Delay Time on Tissue Samples for Metabolomic Studies.
Haukaas, Tonje Husby; Moestue, Siver Andreas; Vettukattil, Muhammad Riyas; Sitter, Beathe; Lamichlane, Santosh; Segura, Reme; Giskeødegård, Guro F.; Bathen, Tone Frost (Journal article; Peer reviewed, 2016-01-28)Introduction: Metabolic profiling of intact tumor tissue by high-resolution magic angle spinning (HR MAS) MR spectroscopy (MRS) provides important biological information possibly useful for clinical diagnosis and development ... -
Impact of Freezing Delay Time on Tissue Samples for Metabolomic Studies.
Haukaas, Tonje Husby; Moestue, Siver Andreas; Vettukattil, Muhammad Riyas; Sitter, Beathe; Lamichlane, Santosh; Segura, Reme; Giskeødegård, Guro F.; Bathen, Tone Frost (Journal article; Peer reviewed, 2016)Introduction: Metabolic profiling of intact tumor tissue by high-resolution magic angle spinning (HR MAS) MR spectroscopy (MRS) provides important biological information possibly useful for clinical diagnosis and development ... -
Increased levels of choline metabolites are an early marker of docetaxel treatment response in BRCA1-mutated mouse mammary tumors: an assessment by ex vivo proton magnetic resonance spectroscopy
van Asten, Jack JA; Vettukattil, Muhammad Riyas; Buckle, Tessa; Rottenberg, Sven; Leeuwen, Fijs van; Bathen, Tone Frost; Heerschap, Arend (Journal article; Peer reviewed, 2015)Abstract Background Docetaxel is one of the most frequently used drugs to treat breast cancer. However, resistance or incomplete response to docetaxel is a major challenge. The aim of this study was to utilize MR ... -
Lipoprotein subfractions by nuclear magnetic resonance are associated with tumor characteristics in breast cancer
Flote, Vidar Gordon; Vettukattil, Muhammad Riyas; Bathen, Tone Frost; Egeland, Thore; McTiernan, Anne; Frydenberg, Hanne; Husøy, Anders; Finstad, Sissi Espetvedt; Lømo, Jon; Garred, Øystein; Schlichting, Ellen; Wist, Erik; Thune, Inger (Journal article; Peer reviewed, 2016)Background: High-Density Lipoprotein (HDL)-cholesterol, has been associated with breast cancer development, but the association is under debate, and whether lipoprotein subfractions is associated with breast tumor ... -
Metabolite and lipoprotein responses and prediction of weight gain during breast cancer treatment
Madssen, Torfinn Støve; Thune, Inger; Flote, Vidar Gordon; Lundgren, Steinar; Bertheussen, Gro Falkener; Frydenberg, Hanne; Wist, Erik; Schlichting, Ellen; Schäfer, Hartmut; Fjøsne, Hans Erikssønn; Vettukattil, Muhammad Riyas; Lømo, Jon; Bathen, Tone Frost; Giskeødegård, Guro F. (Journal article; Peer reviewed, 2018)Background Breast cancer treatment has metabolic side effects, potentially affecting risk of cardiovascular disease (CVD) and recurrence. We aimed to compare alterations in serum metabolites and lipoproteins during treatment ... -
Tissue microstructure is linked to MRI parameters and metabolite levels in prostate cancer
Selnæs, Kirsten Margrete; Vettukattil, Muhammad Riyas; Bertilsson, Helena; Wright, Alan J.; Heerschap, Arend; Angelsen, Anders; Tessem, May-Britt; Bathen, Tone Frost (Peer reviewed; Journal article, 2016)Introduction: Magnetic resonance imaging (MRI) can portray spatial variations in tumor heterogeneity, architecture, and its microenvironment in a non-destructive way. The objective of this study was to assess the relationship ...